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DE69435155D1 - Zusuammensetzungen zur Behandlung von Krebs mittels Viren - Google Patents

Zusuammensetzungen zur Behandlung von Krebs mittels Viren

Info

Publication number
DE69435155D1
DE69435155D1 DE69435155T DE69435155T DE69435155D1 DE 69435155 D1 DE69435155 D1 DE 69435155D1 DE 69435155 T DE69435155 T DE 69435155T DE 69435155 T DE69435155 T DE 69435155T DE 69435155 D1 DE69435155 D1 DE 69435155D1
Authority
DE
Germany
Prior art keywords
compositions
cancer
viruses
treatment
mammal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69435155T
Other languages
English (en)
Inventor
Robert M Lorence
Kirk W Reichard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellstat Biologics Corp
Original Assignee
Wellstat Biologics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellstat Biologics Corp filed Critical Wellstat Biologics Corp
Application granted granted Critical
Publication of DE69435155D1 publication Critical patent/DE69435155D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/768—Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17—Newcastle disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0331—Animal model for proliferative diseases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18132—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69435155T 1993-04-30 1994-04-29 Zusuammensetzungen zur Behandlung von Krebs mittels Viren Expired - Lifetime DE69435155D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5551993A 1993-04-30 1993-04-30

Publications (1)

Publication Number Publication Date
DE69435155D1 true DE69435155D1 (de) 2008-12-04

Family

ID=21998395

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69432409T Expired - Lifetime DE69432409T2 (de) 1993-04-30 1994-04-29 Verwendung der NDV zur Herstellung eines Medikaments zur Krebsbehandlung
DE69435118T Expired - Lifetime DE69435118D1 (de) 1993-04-30 1994-04-29 Gereinigte Zusammensetzungen von Newcastle-Krankheitvirus
DE69435155T Expired - Lifetime DE69435155D1 (de) 1993-04-30 1994-04-29 Zusuammensetzungen zur Behandlung von Krebs mittels Viren

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE69432409T Expired - Lifetime DE69432409T2 (de) 1993-04-30 1994-04-29 Verwendung der NDV zur Herstellung eines Medikaments zur Krebsbehandlung
DE69435118T Expired - Lifetime DE69435118D1 (de) 1993-04-30 1994-04-29 Gereinigte Zusammensetzungen von Newcastle-Krankheitvirus

Country Status (12)

Country Link
US (2) US7056689B1 (de)
EP (4) EP1486211B1 (de)
JP (3) JP4338781B2 (de)
AT (3) ATE411809T1 (de)
AU (1) AU699487B2 (de)
CA (1) CA2161671A1 (de)
DE (3) DE69432409T2 (de)
DK (3) DK0696326T5 (de)
ES (3) ES2310580T3 (de)
HK (1) HK1052871A1 (de)
PT (3) PT1314431E (de)
WO (1) WO1994025627A1 (de)

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US7470426B1 (en) 1997-10-09 2008-12-30 Wellstat Biologics Corporation Treatment of neoplasms with viruses
DE69838340T2 (de) 1997-10-09 2008-05-21 Wellstat Biologics Corp. Behandlung von neoplasmen mit interferonempfindlichen, klonalen viren
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US20040131595A1 (en) * 2002-11-05 2004-07-08 Wellstat Biologics Corporation Treating carcinoid neoplasms with therapeutic viruses
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JPWO2006001120A1 (ja) * 2004-06-24 2008-04-17 株式会社ディナベック研究所 マイナス鎖ｒｎａウイルスを含む抗癌剤
US7767200B2 (en) * 2005-07-14 2010-08-03 Wellstat Biologics Corporation Cancer treatment using viruses, fluoropyrimidines and camptothecins
WO2007064802A1 (en) 2005-12-02 2007-06-07 The Mount Sinai Medical Center Of New York University Chimeric viruses presenting non-native surface proteins and uses thereof
US20090175826A1 (en) * 2006-06-05 2009-07-09 Elankumaran Subbiah Genetically-engineered newcastle disease virus as an oncolytic agent, and methods of using same
US9241998B2 (en) * 2007-05-21 2016-01-26 Board Of Regents, The University Of Texas System Methods and compositions for treatment of cancer using oncolytic RSV activity
WO2010032764A1 (ja) * 2008-09-16 2010-03-25 ジェノミディア株式会社 前立腺癌の治療・予防剤
ES2550179T3 (es) 2009-02-05 2015-11-05 Icahn School Of Medicine At Mount Sinai Virus quiméricos de la enfermedad de Newcastle y usos de los mismos
ATE539148T1 (de) 2009-11-30 2012-01-15 United Cancer Res Inst Neuer klon des geflügelpestvirus, herstellung und anwendung bei der medizinischen behandlung von krebs
GEP20196976B (en) 2013-03-14 2019-06-10 Sloan Kettering Cancer Center Memorial Newcastle disease viruses and uses thereof
CA2940570A1 (en) 2014-02-27 2015-09-03 Viralytics Limited Combination method for treatment of cancer
KR20240073085A (ko) 2017-05-10 2024-05-24 파마 싱크, 엘엘씨 암 치료용 보체 불활성화 내성의 외피 바이러스
JOP20190256A1 (ar) 2017-05-12 2019-10-28 Icahn School Med Mount Sinai فيروسات داء نيوكاسل واستخداماتها

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Also Published As

Publication number Publication date
DE69432409D1 (de) 2003-05-08
US7056689B1 (en) 2006-06-06
EP0696326A4 (de) 1997-08-20
JP2005187484A (ja) 2005-07-14
CA2161671A1 (en) 1994-11-10
US7736640B2 (en) 2010-06-15
ATE236271T1 (de) 2003-04-15
ES2196026T3 (es) 2003-12-16
ATE401092T1 (de) 2008-08-15
EP2009119A1 (de) 2008-12-31
EP1314431A2 (de) 2003-05-28
ES2310580T3 (es) 2009-01-16
EP1486211B1 (de) 2008-10-22
JP4338781B2 (ja) 2009-10-07
JPH09503995A (ja) 1997-04-22
PT1314431E (pt) 2008-10-24
EP0696326B1 (de) 2003-04-02
PT1486211E (pt) 2009-02-02
ES2315595T3 (es) 2009-04-01
DE69435118D1 (de) 2008-08-28
EP1486211A1 (de) 2004-12-15
JP2009149689A (ja) 2009-07-09
DK0696326T3 (da) 2003-06-23
DK1314431T3 (da) 2008-11-10
AU6821394A (en) 1994-11-21
PT696326E (pt) 2003-08-29
EP0696326A1 (de) 1996-02-14
DK0696326T5 (da) 2003-07-14
EP1314431B1 (de) 2008-07-16
EP1314431A3 (de) 2003-06-18
HK1052871A1 (zh) 2003-10-03
DK1486211T3 (da) 2009-01-19
DE69432409T2 (de) 2003-12-24
ATE411809T1 (de) 2008-11-15
WO1994025627A1 (en) 1994-11-10
US20060216310A1 (en) 2006-09-28
AU699487B2 (en) 1998-12-03

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