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DE69132795D1 - Gereinigtes gp120, in dem seine natürliche konformation erhalten bleibt - Google Patents

Gereinigtes gp120, in dem seine natürliche konformation erhalten bleibt

Info

Publication number
DE69132795D1
DE69132795D1 DE69132795T DE69132795T DE69132795D1 DE 69132795 D1 DE69132795 D1 DE 69132795D1 DE 69132795 T DE69132795 T DE 69132795T DE 69132795 T DE69132795 T DE 69132795T DE 69132795 D1 DE69132795 D1 DE 69132795D1
Authority
DE
Germany
Prior art keywords
protein
hiv
binding affinity
substantially identical
properties substantially
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69132795T
Other languages
English (en)
Other versions
DE69132795T2 (de
DE69132795T3 (de
Inventor
L Haigwood
J Scandella
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23949786&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69132795(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of DE69132795D1 publication Critical patent/DE69132795D1/de
Publication of DE69132795T2 publication Critical patent/DE69132795T2/de
Application granted granted Critical
Publication of DE69132795T3 publication Critical patent/DE69132795T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cookers (AREA)
  • Gloves (AREA)
  • Table Devices Or Equipment (AREA)
DE69132795T 1990-03-09 1991-03-08 Gereinigtes gp120, in dem seine natürliche konformation erhalten bleibt Expired - Lifetime DE69132795T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49085890A 1990-03-09 1990-03-09
US490858 1990-03-09
PCT/US1991/001484 WO1991013906A1 (en) 1990-03-09 1991-03-08 PURIFIED gp120 COMPOSITION RETAINING NATURAL CONFORMATION

Publications (3)

Publication Number Publication Date
DE69132795D1 true DE69132795D1 (de) 2001-12-13
DE69132795T2 DE69132795T2 (de) 2002-06-20
DE69132795T3 DE69132795T3 (de) 2008-07-10

Family

ID=23949786

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69132795T Expired - Lifetime DE69132795T3 (de) 1990-03-09 1991-03-08 Gereinigtes gp120, in dem seine natürliche konformation erhalten bleibt

Country Status (8)

Country Link
EP (1) EP0519001B2 (de)
JP (2) JP2624894B2 (de)
AT (1) ATE207930T1 (de)
CA (1) CA2077753C (de)
DE (1) DE69132795T3 (de)
IE (1) IE910779A1 (de)
PT (1) PT96994B (de)
WO (1) WO1991013906A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2077753C (en) * 1990-03-09 2000-02-29 Nancy L. Haigwood Purified gp120 composition retaining natural conformation
ATE125157T1 (de) * 1990-04-03 1995-08-15 Genentech Inc Methoden und zusammensetzungen zur impfung gegen hiv.
US7041293B1 (en) 1990-04-03 2006-05-09 Genentech, Inc. HIV env antibodies
DE59402827D1 (de) † 1993-01-16 1997-06-26 Manfred Dr Schawaller Verfahren zur gewinnung nativer, oligomerer, glykosylierter ektodomänen viraler membranproteine, deren verwendung, insbesondere als impfstoff gegen hiv
EP0708659A4 (de) * 1993-06-07 2000-08-23 Genentech Inc Hiv hüllpolypeptid
EP0751988B1 (de) * 1994-03-22 2000-02-09 The Immune Response Corporation Die hocheffiziente herstellung und isolierung von viruspartikeln
KR100374308B1 (ko) * 1995-07-27 2003-12-18 주식회사 엘지생명과학 재조합차이니스햄스터오바리세포로부터발현된수두바이러스의지피i당단백질의정제방법
US6585979B1 (en) 1996-07-08 2003-07-01 Genentech, Inc. HIV envelope polypeptides and immunogenic composition
US6689879B2 (en) 1998-12-31 2004-02-10 Chiron Corporation Modified HIV Env polypeptides
JP2003523721A (ja) 1998-12-31 2003-08-12 カイロン コーポレイション 抗原性ｈｉｖｃ型ポリペプチドをコードするポリヌクレオチド、ポリペプチド、およびそれらの使用
AU2221600A (en) 1998-12-31 2000-07-31 Chiron Corporation Improved expression of hiv polypeptides and production of virus-like particles
AU2002320314A1 (en) 2001-07-05 2003-01-21 Chiron, Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
US20030170614A1 (en) 2001-08-31 2003-09-11 Megede Jan Zur Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof
US7786288B2 (en) * 2003-10-23 2010-08-31 Karp Nelson M Immunizing compositions encoding an epitope obtained from the HIV-1 capsid protein cyclophilin A binding site
JPWO2006011580A1 (ja) * 2004-07-27 2008-05-01 ジェノミディア株式会社 ウイルスエンベロープの精製方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01120284A (ja) * 1987-11-05 1989-05-12 Shiro Kato Ｈｉｖ不完全粒子および該製造方法
CA2077753C (en) * 1990-03-09 2000-02-29 Nancy L. Haigwood Purified gp120 composition retaining natural conformation

Also Published As

Publication number Publication date
JPH09227588A (ja) 1997-09-02
PT96994A (pt) 1991-10-31
EP0519001A1 (de) 1992-12-23
CA2077753A1 (en) 1991-09-10
PT96994B (pt) 1998-07-31
EP0519001B2 (de) 2007-12-19
ATE207930T1 (de) 2001-11-15
WO1991013906A1 (en) 1991-09-19
IE910779A1 (en) 1991-09-11
DE69132795T2 (de) 2002-06-20
CA2077753C (en) 2000-02-29
DE69132795T3 (de) 2008-07-10
JP2624894B2 (ja) 1997-06-25
JPH05505616A (ja) 1993-08-19
EP0519001B1 (de) 2001-10-31

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS, INC., EMERY, US

8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS,INC.(N.D.GES, US