ES2075196T3 - Metodo para el uso y la sintesis de peptidos. - Google Patents
Metodo para el uso y la sintesis de peptidos.Info
- Publication number
- ES2075196T3 ES2075196T3 ES90903300T ES90903300T ES2075196T3 ES 2075196 T3 ES2075196 T3 ES 2075196T3 ES 90903300 T ES90903300 T ES 90903300T ES 90903300 T ES90903300 T ES 90903300T ES 2075196 T3 ES2075196 T3 ES 2075196T3
- Authority
- ES
- Spain
- Prior art keywords
- mixture
- peptides
- synthesis
- specific binding
- entities
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 230000027455 binding Effects 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 230000009870 specific binding Effects 0.000 abstract 3
- 238000000926 separation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/824—Immunological separation techniques
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
SE PRESENTA UN METODO PARA LA SEPARACION DE AL MENOS UN ORGANISMO ESPECIFICO AGLOMERADO DE UNA MEZCLA DE ORGANISMOS AGLOMERADOS QUE COMPRENDE LAS FASES CORRESPONDIENTES A LA RELACCION DE DICHA MEZCLA DE ORGANISMOS AGLOMERADOS CON UN PEPTIDO INMOBILIZADO, EN LA CUAL DICHO PEPTIDO, AGLUTINA ESPECIFICAMENTE A DICHA AGLOMERACION DE ORGANISMOS, SEPARANDO EL COMPLEJO DE ORGANISMOS AGLOMERADOS DEL PEPTIDO ESPECIFICO INMOBILIZADO, DE LAS MEZCLAS DE ORGANISMOS AGLOMERANTES. TAMBIEN SE DESARROLLA UN PREPARADO DE MANTENIMIENTO DE PEPTIDO/SOLIDOS INMOBILIZADOS COMPRENDIENDO UN ENLACE DIASOCIADO ENTRE EL PEPTIDO Y EL SOPORTE SOLIDO Y ASI MISMO SE PRESENTA UN METODO PARA LA PREPARACION DE UN PEPTIDO A PARTIR DE UN SOPORTE DE PEPTIDO INDELEBLE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPJ278889 | 1989-02-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2075196T3 true ES2075196T3 (es) | 1995-10-01 |
Family
ID=3773722
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90903300T Expired - Lifetime ES2075196T3 (es) | 1989-02-17 | 1990-02-16 | Metodo para el uso y la sintesis de peptidos. |
Country Status (12)
Country | Link |
---|---|
US (2) | US5539084A (es) |
EP (2) | EP0628570A1 (es) |
JP (1) | JPH04504416A (es) |
AT (1) | ATE123780T1 (es) |
AU (1) | AU642403B2 (es) |
CA (1) | CA2047191A1 (es) |
DE (1) | DE69020143T2 (es) |
DK (1) | DK0458841T3 (es) |
ES (1) | ES2075196T3 (es) |
NO (1) | NO301279B1 (es) |
NZ (1) | NZ232562A (es) |
WO (1) | WO1990009395A1 (es) |
Families Citing this family (87)
Publication number | Priority date | Publication date | Assignee | Title |
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US5866363A (en) | 1985-08-28 | 1999-02-02 | Pieczenik; George | Method and means for sorting and identifying biological information |
US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
US5959087A (en) * | 1989-08-07 | 1999-09-28 | Peptide Technology, Ltd. | Tumour necrosis factor binding ligands |
US20030225254A1 (en) | 1989-08-07 | 2003-12-04 | Rathjen Deborah Ann | Tumour necrosis factor binding ligands |
EP0486526B2 (en) | 1989-08-07 | 2001-03-07 | Peptech Limited | Tumour necrosis factor binding ligands |
DE3935572A1 (de) * | 1989-10-25 | 1991-05-02 | Biotechnolog Forschung Gmbh | Verfahren zur peptidsynthese und traeger dafuer |
AU1248292A (en) | 1990-12-06 | 1992-07-08 | Affymax Technologies N.V. | Sequencing by hybridization of a target nucleic acid to a matrix of defined oligonucleotides |
US20010021513A1 (en) * | 1991-11-21 | 2001-09-13 | Puijk Wouter Cornelis | Test device comprising a plate containing a multiplicity of wells with an associated metering device, as well as a kit which comprises these devices and use of the devices |
EP0545198B1 (de) * | 1991-11-29 | 1999-09-15 | Hoechst Aktiengesellschaft | Peptide mit insulinartiger Wirkung |
AU4580093A (en) * | 1992-07-22 | 1994-02-14 | Proteus Molecular Design Limited | Polypeptide antigens of mycobacterium bovis |
US5324483B1 (en) * | 1992-10-08 | 1996-09-24 | Warner Lambert Co | Apparatus for multiple simultaneous synthesis |
US5567391A (en) * | 1992-10-08 | 1996-10-22 | Warner-Lambert Company | Apparatus for multiple simultaneous synthesis |
US5702672A (en) * | 1992-10-08 | 1997-12-30 | Warner-Lambert Company | Apparatus and method for multiple simultaneous synthesis |
US5714127A (en) * | 1992-10-08 | 1998-02-03 | Warner-Lambert Company | System for multiple simultaneous synthesis |
NZ257077A (en) * | 1992-11-06 | 1997-05-26 | Chiron Mimotopes Pty Ltd | Support for synthesis of modular polymers |
PT1156059E (pt) * | 1993-06-21 | 2007-10-19 | Aventis Pharma Inc | Ligantes cliváveis selectivamente com base num grupo de metionina e um grupo éster |
US5380668A (en) * | 1993-07-06 | 1995-01-10 | University Of Utah Research Foundation | Compounds having the antigenicity of hCG |
WO1996020947A1 (en) * | 1994-12-30 | 1996-07-11 | Chiron Corporation | Method for the controlled synthesis of polynucleotide mixtures which encode desired mixtures of peptides |
US5958792A (en) * | 1995-06-07 | 1999-09-28 | Chiron Corporation | Combinatorial libraries of substrate-bound cyclic organic compounds |
WO1997012897A1 (en) * | 1995-10-03 | 1997-04-10 | The Penn State Research Foundation | Method to identify a surface-bound molecule |
US20060269532A1 (en) * | 1997-02-25 | 2006-11-30 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
US20060024301A1 (en) * | 1997-02-25 | 2006-02-02 | Corixa Corporation | Prostate-specific polypeptides and fusion polypeptides thereof |
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US20030185830A1 (en) * | 1997-02-25 | 2003-10-02 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
WO1998038158A1 (en) * | 1997-02-26 | 1998-09-03 | Eli Lilly And Company | Process for preparing pharmaceutical compounds |
US7282198B2 (en) * | 1997-03-19 | 2007-10-16 | The University Of Arkansas For Medical Sciences | Immunotherapeutic methods targeted towards stratum corneum chymotryptic enzyme |
US7335351B2 (en) * | 1997-03-19 | 2008-02-26 | The University Of Arkansas For Medical Sciences | Immunotherapeutic methods targeted towards stratum corneum chymotryptic enzyme |
US6294344B1 (en) * | 1997-03-19 | 2001-09-25 | The Board Of Trustees Of The University Of Arkansas | Methods for the early diagnosis of ovarian cancer |
US7084239B1 (en) * | 1997-10-08 | 2006-08-01 | The United States Of America As Represented By The Department Of Health And Human Services | Cancer peptides of NY-ESO-1/CAG-3 |
US20020061848A1 (en) * | 2000-07-20 | 2002-05-23 | Ajay Bhatia | Compounds and methods for treatment and diagnosis of chlamydial infection |
US20030235594A1 (en) * | 1999-09-14 | 2003-12-25 | Antigen Express, Inc. | Ii-Key/antigenic epitope hybrid peptide vaccines |
US9289487B2 (en) * | 1999-09-14 | 2016-03-22 | Antigen Express, Inc. | II-key/antigenic epitope hybrid peptide vaccines |
US6432409B1 (en) * | 1999-09-14 | 2002-08-13 | Antigen Express, Inc. | Hybrid peptides modulate the immune response |
US6919187B2 (en) * | 2000-04-21 | 2005-07-19 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
US6656700B2 (en) | 2000-05-26 | 2003-12-02 | Amersham Plc | Isoforms of human pregnancy-associated protein-E |
EP1303559A4 (en) * | 2000-07-14 | 2004-06-30 | Mimotopes Pty Ltd | ACTIVATED, PROPFCOPOLYMERIZED SURFACES IN MODULAR DESIGN |
JP4503801B2 (ja) * | 2000-09-08 | 2010-07-14 | 独立行政法人科学技術振興機構 | 新規ヒト癌・精巣抗原及びその遺伝子 |
US20020123474A1 (en) * | 2000-10-04 | 2002-09-05 | Shannon Mark E. | Human GTP-Rho binding protein2 |
AU3941002A (en) * | 2000-10-31 | 2002-06-03 | Zycos Inc | Cyp1b1 nucleic acids and methods of use |
WO2002069907A2 (en) * | 2001-03-07 | 2002-09-12 | Mannkind Corporation | Anti-neovasculature preparations for cancer |
US20040078837A1 (en) * | 2001-08-02 | 2004-04-22 | Shannon Mark E. | Four human zinc-finger-containing proteins: MDZ3, MDZ4, MDZ7 and MDZ12 |
DK1530637T3 (da) * | 2002-02-26 | 2010-05-31 | Genencor Int | Carlsberg-subtilisin-proteiner med nedsat immunogenitet |
AU2003243151A1 (en) * | 2002-08-16 | 2004-03-03 | Agensys, Inc. | Nucleic acid and corresponding protein entitled 251p5g2 useful in treatment and detection of cancer |
US7179645B2 (en) * | 2002-09-24 | 2007-02-20 | Antigen Express, Inc. | Ii-Key/antigenic epitope hybrid peptide vaccines |
CA2499123A1 (en) | 2002-09-17 | 2004-04-15 | Antigen Express, Inc. | Ii-key/antigenic epitope hybrid peptide vaccines |
US6910785B2 (en) * | 2003-01-22 | 2005-06-28 | Cooper Technologies Company | Industrial luminaire with prismatic refractor |
US20040185499A1 (en) * | 2003-03-20 | 2004-09-23 | Jolley Michael E. | Method of epitope scanning using fluorescence polarization |
US20050095648A1 (en) * | 2003-10-30 | 2005-05-05 | Mario Geysen | Method for designing linear epitopes and algorithm therefor and polypeptide epitopes |
PT1910839T (pt) * | 2005-07-27 | 2016-07-14 | Oncotherapy Science Inc | Gene tom34 relacionado com o cancro do cólon |
CA2628241C (en) | 2005-11-07 | 2016-02-02 | Indiana University Research And Technology Corporation | Glucagon analogs exhibiting physiological solubility and stability |
JP5890085B2 (ja) * | 2007-01-05 | 2016-03-22 | インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation | 生理学的pHの緩衝液中で向上した溶解度を示すグルカゴン類縁体 |
GEP20135944B (en) | 2007-02-15 | 2013-10-25 | Indiana Unversity Research And Tech Corporation | Glucagon/glp-1 receptor co-agonists |
EP2044949A1 (en) | 2007-10-05 | 2009-04-08 | Immutep | Use of recombinant lag-3 or the derivatives thereof for eliciting monocyte immune response |
MX2010004297A (es) | 2007-10-30 | 2010-05-03 | Univ Indiana Res & Tech Corp | Antagonistas de glucagon. |
EP2214691B1 (en) * | 2007-10-30 | 2015-09-30 | Indiana University Research and Technology Corporation | Compounds exhibiting glucagon antagonist and glp-1 agonist activity |
WO2009099763A1 (en) * | 2008-01-30 | 2009-08-13 | Indiana University Research And Technology Corporation | Ester-based peptide prodrugs |
KR20110040760A (ko) * | 2008-06-17 | 2011-04-20 | 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 | 대사 질환 및 비만 치료용 gip-기초된 혼합형 항진제 |
EA019203B9 (ru) | 2008-06-17 | 2014-03-31 | Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн | Коагонисты глюкагонового рецептора/glp-1-рецептора |
EP2307037A4 (en) * | 2008-06-17 | 2011-08-03 | Univ Indiana Res & Tech Corp | GLUCAGON ANALOGUE WITH IMPROVED SOLUBILITY AND STABILITY IN PHYSIOLOGICAL PH BUFFERS |
KR20110110174A (ko) | 2008-12-19 | 2011-10-06 | 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 | 아미드 기반 글루카곤 슈퍼패밀리 펩티드 프로드럭 |
CA2750922A1 (en) * | 2009-01-28 | 2010-08-05 | Antigen Express, Inc. | Li-key hybrid peptides that modulate the immune response to influenza |
MX2011013625A (es) | 2009-06-16 | 2012-01-20 | Univ Indiana Res & Tech Corp | Compuestos glucagon activo de receptor de gip. |
WO2011075393A2 (en) | 2009-12-18 | 2011-06-23 | Indiana University Research And Technology Corporation | Glucagon/glp-1 receptor co-agonists |
RU2012136450A (ru) | 2010-01-27 | 2014-03-10 | Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн | Конъюгаты антагонист глюкагона - агонист gip и композиции для лечения метаболических расстройств и ожирения |
CN103079587B (zh) | 2010-05-13 | 2016-05-11 | 印第安纳大学研究及科技有限公司 | 呈现核激素受体活性的胰高血糖素超家族肽 |
BR112012028707A2 (pt) | 2010-05-13 | 2019-09-24 | Univ Indiana Res & Tech Corp | composto de glucagon da superfamília de peptídeos exibindo atividade do receptor g com proteína acoplada, pró farmaco, dímero ou multímro, composição farmacêutica que o compreendem e método de administração do mesmo. |
US8778872B2 (en) | 2010-06-24 | 2014-07-15 | Indiana University Research And Technology Corporation | Amide based glucagon superfamily peptide prodrugs |
US8802819B2 (en) * | 2010-10-29 | 2014-08-12 | Lonza Ltd. | Diketopiperazine forming dipeptidyl linker |
SG190407A1 (en) | 2010-12-02 | 2013-06-28 | Oncotherapy Science Inc | Tomm34 peptides and vaccines including the same |
BR112013015389A2 (pt) | 2010-12-22 | 2016-11-22 | Univ Indiana Res & Tech Corp | análogo de glucagon exibindo atividade de receptor gip |
MX347703B (es) | 2011-06-22 | 2017-05-09 | Univ Indiana Res & Tech Corp | Co-agonistas del receptor de glucagon/glp-1. |
AU2012273365A1 (en) | 2011-06-22 | 2014-01-16 | Indiana University Research And Technology Corporation | Glucagon/glp-1 receptor co-agonists |
JP6324315B2 (ja) | 2011-11-17 | 2018-05-16 | インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation | グルココルチコイド受容体の活性を示すグルカゴンスーパーファミリーのペプチド |
EP2639299A1 (en) | 2012-03-16 | 2013-09-18 | Invectys | Universal cancer peptides derived from telomerase |
ES2602486T3 (es) | 2012-06-21 | 2017-02-21 | Indiana University Research And Technology Corporation | Análogos de glucagón que muestran actividad de receptor de GIP |
WO2014158900A1 (en) | 2013-03-14 | 2014-10-02 | Indiana University Research And Technology Corporation | Insulin-incretin conjugates |
EP2978445B1 (en) | 2013-03-28 | 2018-07-04 | Invectys | A cancer vaccine for cats |
CA2908143C (en) | 2013-03-28 | 2021-08-31 | Invectys | A cancer vaccine for dogs |
NZ719098A (en) | 2013-10-28 | 2022-08-26 | Invectys | A telomerase encoding dna vaccine |
CA2927539A1 (en) | 2013-10-28 | 2015-05-07 | Invectys | Gene electrotransfer into skin cells |
GB201322626D0 (en) | 2013-12-19 | 2014-02-05 | Immutep S A | Combined preparations for the treatment of cancer |
US9682123B2 (en) | 2013-12-20 | 2017-06-20 | The Trustees Of Columbia University In The City Of New York | Methods of treating metabolic disease |
US10232020B2 (en) | 2014-09-24 | 2019-03-19 | Indiana University Research And Technology Corporation | Incretin-insulin conjugates |
GB201500374D0 (en) | 2015-01-09 | 2015-02-25 | Immutep S A | Combined preparations for the treatment of cancer |
ES2950426T3 (es) | 2015-08-12 | 2023-10-09 | Univ Columbia | Procedimientos de tratamiento de la depleción de volumen y la lesión renal |
WO2018206512A1 (en) | 2017-05-09 | 2018-11-15 | Invectys | Recombinant measles vaccine expressing htert |
KR20240133644A (ko) * | 2023-02-27 | 2024-09-04 | 에스피투티엑스주식회사 | 응집 방지 기능을 갖는 생물학적 고분자 합성용 기재 및 이를 이용한 생물학적 고분자 합성 방법 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3983001A (en) * | 1972-05-10 | 1976-09-28 | Ceskoslovenska Akademie Ved | Isolation of biologically active compounds by affinity chromatography |
US3988307A (en) * | 1974-09-06 | 1976-10-26 | The United States Of America As Represented By The Secretary Of The Department Of Health, Education And Welfare | Solid phase synthesis of peptides with carboxyl-terminal amides |
US5133866A (en) * | 1988-03-24 | 1992-07-28 | Terrapin Technologies, Inc. | Method to identify analyte-bending ligands |
US4963263A (en) * | 1988-03-24 | 1990-10-16 | Terrapin Technologies, Inc. | Method of identity analyte-binding peptides |
US5217869A (en) * | 1987-10-13 | 1993-06-08 | Terrapin Technologies, Inc. | Method to produce immunodiagnostic reagents |
US5340474A (en) * | 1988-03-24 | 1994-08-23 | Terrapin Technologies, Inc. | Panels of analyte-binding ligands |
US5409611A (en) * | 1988-03-24 | 1995-04-25 | Terrapin Technoogies, Inc. | Method to identify analyte-binding ligands |
-
1990
- 1990-02-16 EP EP94201174A patent/EP0628570A1/en not_active Withdrawn
- 1990-02-16 AT AT90903300T patent/ATE123780T1/de active
- 1990-02-16 EP EP90903300A patent/EP0458841B1/en not_active Expired - Lifetime
- 1990-02-16 CA CA002047191A patent/CA2047191A1/en not_active Abandoned
- 1990-02-16 AU AU49869/90A patent/AU642403B2/en not_active Ceased
- 1990-02-16 ES ES90903300T patent/ES2075196T3/es not_active Expired - Lifetime
- 1990-02-16 DK DK90903300.3T patent/DK0458841T3/da not_active Application Discontinuation
- 1990-02-16 WO PCT/AU1990/000062 patent/WO1990009395A1/en active IP Right Grant
- 1990-02-16 JP JP2503570A patent/JPH04504416A/ja active Pending
- 1990-02-16 NZ NZ232562A patent/NZ232562A/xx unknown
- 1990-02-16 US US07/752,437 patent/US5539084A/en not_active Expired - Lifetime
- 1990-02-16 DE DE69020143T patent/DE69020143T2/de not_active Expired - Fee Related
-
1991
- 1991-08-15 NO NO913186A patent/NO301279B1/no unknown
-
1995
- 1995-06-07 US US08/475,213 patent/US5783674A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5539084A (en) | 1996-07-23 |
NO913186D0 (no) | 1991-08-15 |
EP0458841A4 (en) | 1992-08-26 |
AU4986990A (en) | 1990-08-23 |
AU642403B2 (en) | 1993-10-21 |
CA2047191A1 (en) | 1990-08-18 |
NO913186L (no) | 1991-08-15 |
ATE123780T1 (de) | 1995-06-15 |
NO301279B1 (no) | 1997-10-06 |
US5783674A (en) | 1998-07-21 |
EP0458841B1 (en) | 1995-06-14 |
DE69020143D1 (de) | 1995-07-20 |
NZ232562A (en) | 1992-10-28 |
DE69020143T2 (de) | 1996-01-25 |
WO1990009395A1 (en) | 1990-08-23 |
EP0458841A1 (en) | 1991-12-04 |
JPH04504416A (ja) | 1992-08-06 |
EP0628570A1 (en) | 1994-12-14 |
DK0458841T3 (da) | 1995-11-20 |
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