DE69122122D1 - Hydroxamsäuren zur prävention von peperfusionsschäden - Google Patents
Hydroxamsäuren zur prävention von peperfusionsschädenInfo
- Publication number
- DE69122122D1 DE69122122D1 DE69122122T DE69122122T DE69122122D1 DE 69122122 D1 DE69122122 D1 DE 69122122D1 DE 69122122 T DE69122122 T DE 69122122T DE 69122122 T DE69122122 T DE 69122122T DE 69122122 D1 DE69122122 D1 DE 69122122D1
- Authority
- DE
- Germany
- Prior art keywords
- pct
- damage
- date
- peperfusion
- preventing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000006378 damage Effects 0.000 title abstract 2
- NEAQRZUHTPSBBM-UHFFFAOYSA-N 2-hydroxy-3,3-dimethyl-7-nitro-4h-isoquinolin-1-one Chemical class C1=C([N+]([O-])=O)C=C2C(=O)N(O)C(C)(C)CC2=C1 NEAQRZUHTPSBBM-UHFFFAOYSA-N 0.000 title 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 206010063837 Reperfusion injury Diseases 0.000 abstract 1
- 230000003683 cardiac damage Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Catching Or Destruction (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909024820A GB9024820D0 (en) | 1990-11-15 | 1990-11-15 | Pharmaceutical compositions |
| PCT/GB1991/002017 WO1992008453A1 (en) | 1990-11-15 | 1991-11-15 | Hydroxamic acids for preventing reperfusion injury |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69122122D1 true DE69122122D1 (de) | 1996-10-17 |
| DE69122122T2 DE69122122T2 (de) | 1997-03-06 |
Family
ID=10685402
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69122122T Expired - Fee Related DE69122122T2 (de) | 1990-11-15 | 1991-11-15 | Hydroxamsäuren zur prävention von peperfusionsschäden |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5506266A (de) |
| EP (1) | EP0559677B1 (de) |
| JP (1) | JPH06504988A (de) |
| AT (1) | ATE142487T1 (de) |
| AU (1) | AU661980B2 (de) |
| CA (1) | CA2095606A1 (de) |
| DE (1) | DE69122122T2 (de) |
| ES (1) | ES2091949T3 (de) |
| GB (2) | GB9024820D0 (de) |
| WO (1) | WO1992008453A1 (de) |
| ZA (1) | ZA919069B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5508308A (en) * | 1992-04-16 | 1996-04-16 | Abbott Laboratories | Use of pyruvylglycine to treat ischemia/reperfusion injury following myocardial infarction |
| AU747898B2 (en) * | 1997-03-03 | 2002-05-30 | Bristol-Myers Squibb Company | Monoclonal antibodies to human CD6 |
| US5883131A (en) * | 1997-07-09 | 1999-03-16 | Pfizer Inc. | Cyclic sulfone derivatives |
| EP1153010A1 (de) | 1999-02-08 | 2001-11-14 | Checkpoint Genetics, Inc. | N-substituierte aminosäuren, pharmazeutische antioxidant-zusammensetzungen die diese enthalten und verfahren zu ihrer anwendung |
| US6767741B1 (en) | 1999-08-27 | 2004-07-27 | Invitrogen Corporation | Metal binding compounds and their use in cell culture medium compositions |
| DE10222561B4 (de) * | 2002-05-17 | 2009-12-10 | Dr. Franz Köhler Chemie GmbH | Protektive Lösung zur Verhinderung von Ischämieschäden |
| US10531655B2 (en) | 2011-12-02 | 2020-01-14 | The Regents Of The University Of California | Reperfusion protection solution and uses thereof |
| CN109844717B (zh) | 2016-08-14 | 2023-05-23 | 利维帕尔森有限公司 | 用于移动应用程序的实时远程控制的系统和方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4604407A (en) * | 1985-04-04 | 1986-08-05 | E. R. Squibb & Sons, Inc. | Hydroxamates |
| US4861798A (en) * | 1986-12-29 | 1989-08-29 | Bristol-Myers Company | Lipoxygenase inhibitory compounds |
| US5223538A (en) * | 1987-03-31 | 1993-06-29 | Duke University | Superoxide dismutase mimic |
| JPH02196767A (ja) * | 1988-10-11 | 1990-08-03 | Kyowa Hakko Kogyo Co Ltd | ヒドロキサム酸誘導体 |
| US5187192A (en) * | 1992-03-13 | 1993-02-16 | Abbott Laboratories | Cyclobutyl derivatives having lipoxygenase inhibitory activity |
-
1990
- 1990-11-15 GB GB909024820A patent/GB9024820D0/en active Pending
-
1991
- 1991-11-15 EP EP91920065A patent/EP0559677B1/de not_active Expired - Lifetime
- 1991-11-15 WO PCT/GB1991/002017 patent/WO1992008453A1/en active IP Right Grant
- 1991-11-15 DE DE69122122T patent/DE69122122T2/de not_active Expired - Fee Related
- 1991-11-15 CA CA002095606A patent/CA2095606A1/en not_active Abandoned
- 1991-11-15 JP JP3518113A patent/JPH06504988A/ja active Pending
- 1991-11-15 GB GB9124272A patent/GB2252246B/en not_active Expired - Fee Related
- 1991-11-15 ZA ZA919069A patent/ZA919069B/xx unknown
- 1991-11-15 US US08/064,151 patent/US5506266A/en not_active Expired - Fee Related
- 1991-11-15 AU AU89067/91A patent/AU661980B2/en not_active Ceased
- 1991-11-15 AT AT91920065T patent/ATE142487T1/de active
- 1991-11-15 ES ES91920065T patent/ES2091949T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ZA919069B (en) | 1992-09-30 |
| GB2252246A (en) | 1992-08-05 |
| CA2095606A1 (en) | 1992-05-16 |
| GB2252246B (en) | 1995-03-15 |
| EP0559677B1 (de) | 1996-09-11 |
| WO1992008453A1 (en) | 1992-05-29 |
| ATE142487T1 (de) | 1996-09-15 |
| GB9124272D0 (en) | 1992-01-08 |
| EP0559677A1 (de) | 1993-09-15 |
| DE69122122T2 (de) | 1997-03-06 |
| US5506266A (en) | 1996-04-09 |
| AU661980B2 (en) | 1995-08-17 |
| GB9024820D0 (en) | 1991-01-02 |
| AU8906791A (en) | 1992-06-11 |
| JPH06504988A (ja) | 1994-06-09 |
| ES2091949T3 (es) | 1996-11-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |