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ES2094545T3 - Derivados n-substituidos del 3-azabiciclo(3.2.0)heptano, como neurolepticos etc.. - Google Patents

Derivados n-substituidos del 3-azabiciclo(3.2.0)heptano, como neurolepticos etc..

Info

Publication number
ES2094545T3
ES2094545T3 ES93912912T ES93912912T ES2094545T3 ES 2094545 T3 ES2094545 T3 ES 2094545T3 ES 93912912 T ES93912912 T ES 93912912T ES 93912912 T ES93912912 T ES 93912912T ES 2094545 T3 ES2094545 T3 ES 2094545T3
Authority
ES
Spain
Prior art keywords
pct
neurolepticos
azabiciclo
heptane
substituted derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93912912T
Other languages
English (en)
Inventor
Gerd Steiner
Liliane Unger
Berthold Behl
Hans-Juergen Teschendorf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of ES2094545T3 publication Critical patent/ES2094545T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

SE DESCRIBEN COMPUESTOS DE LA FORMULA (I), DONDE LOS SUSTITUYENTES POSEEN EL SIGNIFICADO DADO EN LA DESCRIPCION, ASI COMO SU ELABORACION. LOS NUEVOS COMPUESTOS SON APROPIADOS PARA EL TRATAMIENTO DE ENFERMEDADES.
ES93912912T 1992-06-19 1993-06-08 Derivados n-substituidos del 3-azabiciclo(3.2.0)heptano, como neurolepticos etc.. Expired - Lifetime ES2094545T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4219973A DE4219973A1 (de) 1992-06-19 1992-06-19 N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
ES2094545T3 true ES2094545T3 (es) 1997-01-16

Family

ID=6461299

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93912912T Expired - Lifetime ES2094545T3 (es) 1992-06-19 1993-06-08 Derivados n-substituidos del 3-azabiciclo(3.2.0)heptano, como neurolepticos etc..

Country Status (14)

Country Link
US (1) US5521209A (es)
EP (1) EP0646110B1 (es)
JP (1) JP3171261B2 (es)
AT (1) ATE144497T1 (es)
BG (1) BG62349B2 (es)
CA (1) CA2138287C (es)
DE (2) DE4219973A1 (es)
DK (1) DK0646110T3 (es)
ES (1) ES2094545T3 (es)
GR (1) GR3021736T3 (es)
MX (1) MX9303605A (es)
SG (1) SG82540A1 (es)
TW (1) TW261614B (es)
WO (1) WO1994000431A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527910A (en) * 1992-12-30 1996-06-18 Cheil Foods & Chemicals, Inc. Pyridone carboxylic acid compounds and their uses for treating infectious diseases caused by bacteria
DE4341402A1 (de) * 1993-12-04 1995-06-08 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE4341403A1 (de) * 1993-12-04 1995-06-08 Basf Ag N-substituierte 3-Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
DE4427647A1 (de) * 1994-08-04 1996-02-08 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
OA11581A (en) 1998-07-17 2004-07-23 Agouron Pharma Compounds, compositions, and methods for stimulating neuronal growth and elongation.
DE19836404A1 (de) * 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE19836406A1 (de) 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
US6458821B1 (en) 1998-08-12 2002-10-01 Abbott Laboratories N-substituted azabicycloheptane derivatives, production and use thereof
DE19848521A1 (de) * 1998-10-21 2000-04-27 Basf Ag Verfahren zur Herstellung von (+)-exo-6-Phenyl-3-azabicyclo-[3.2.0]heptanen
JP4754570B2 (ja) * 2004-10-14 2011-08-24 アボット ゲーエムベーハー ウント カンパニー カーゲー ドーパミンｄ３受容体の調節に応答する障害の治療に好適なアザビシクロヘプチル化合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL110185C (es) * 1958-04-22
US3328390A (en) * 1962-02-27 1967-06-27 Tri Kem Corp Certain azabicycloalkane compounds
NO154582C (no) * 1978-10-20 1986-11-05 Ferrosan Ab Analogifremgangsmaate for fremstilling av terapeutisk aktive difenyl-dibutylpiperazinkarboksamider.
US4605655A (en) * 1984-03-06 1986-08-12 Bristol-Myers Company Antipsychotic 1-fluorophenylbutyl-4-(2-pyrimidinyl)piperazine derivatives
DE3571436D1 (en) * 1984-12-21 1989-08-17 Duphar Int Res New pharmaceutical compositions having anti-psychotic properties
US4994460A (en) * 1989-06-01 1991-02-19 Bristol-Myers Squibb Co. Agents for treatment of brain ischemia
US5055470A (en) * 1989-06-01 1991-10-08 Bristol-Myers Squibb Co. Method of treatment of ischemia in brain
DE4112353A1 (de) * 1991-04-16 1992-10-22 Basf Ag 1,3,4-trisubstituierte piperidin-derivate, ihre herstellung und verwendung

Also Published As

Publication number Publication date
MX9303605A (es) 1993-12-01
TW261614B (es) 1995-11-01
JP3171261B2 (ja) 2001-05-28
US5521209A (en) 1996-05-28
CA2138287A1 (en) 1994-01-06
JPH07508012A (ja) 1995-09-07
BG62349B2 (bg) 1999-08-31
EP0646110A1 (de) 1995-04-05
DE59304311D1 (de) 1996-11-28
GR3021736T3 (en) 1997-02-28
EP0646110B1 (de) 1996-10-23
SG82540A1 (en) 2001-08-21
CA2138287C (en) 2005-03-01
ATE144497T1 (de) 1996-11-15
WO1994000431A1 (de) 1994-01-06
DK0646110T3 (da) 1996-11-18
DE4219973A1 (de) 1993-12-23

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