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DE60224524D1 - Verfahren zur Sequenzierung von Polynukleotiden - Google Patents

Verfahren zur Sequenzierung von Polynukleotiden

Info

Publication number
DE60224524D1
DE60224524D1 DE60224524T DE60224524T DE60224524D1 DE 60224524 D1 DE60224524 D1 DE 60224524D1 DE 60224524 T DE60224524 T DE 60224524T DE 60224524 T DE60224524 T DE 60224524T DE 60224524 D1 DE60224524 D1 DE 60224524D1
Authority
DE
Germany
Prior art keywords
polynucleotide
enzyme
effect
linear
sequencing polynucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60224524T
Other languages
English (en)
Other versions
DE60224524T2 (de
Inventor
Daniel Henry Densham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medical Biosystems Ltd
Original Assignee
Medical Biosystems Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Biosystems Ltd filed Critical Medical Biosystems Ltd
Publication of DE60224524D1 publication Critical patent/DE60224524D1/de
Application granted granted Critical
Publication of DE60224524T2 publication Critical patent/DE60224524T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
DE60224524T 2001-05-18 2002-05-20 Verfahren zur Sequenzierung von Polynukleotiden Expired - Fee Related DE60224524T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0112238.1A GB0112238D0 (en) 2001-05-18 2001-05-18 Sequencing method
GB0112238 2001-05-18
PCT/GB2002/002345 WO2002095070A2 (en) 2001-05-18 2002-05-20 Polynucleotide sequencing method

Publications (2)

Publication Number Publication Date
DE60224524D1 true DE60224524D1 (de) 2008-02-21
DE60224524T2 DE60224524T2 (de) 2009-01-08

Family

ID=9914926

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60224524T Expired - Fee Related DE60224524T2 (de) 2001-05-18 2002-05-20 Verfahren zur Sequenzierung von Polynukleotiden

Country Status (21)

Country Link
US (3) US9476094B2 (de)
EP (1) EP1389241B1 (de)
JP (2) JP4094961B2 (de)
KR (1) KR20030094412A (de)
CN (1) CN1537172B (de)
AT (1) ATE383442T1 (de)
AU (1) AU2002257933B2 (de)
BR (1) BR0209841A (de)
CA (1) CA2447222C (de)
DE (1) DE60224524T2 (de)
DK (1) DK1389241T3 (de)
ES (1) ES2299569T3 (de)
GB (1) GB0112238D0 (de)
HK (1) HK1061047A1 (de)
IL (1) IL158743A0 (de)
IS (1) IS7039A (de)
MX (1) MXPA03010411A (de)
NZ (1) NZ529349A (de)
PT (1) PT1389241E (de)
RU (1) RU2291197C2 (de)
WO (1) WO2002095070A2 (de)

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GB0112238D0 (en) * 2001-05-18 2001-07-11 Medical Biosystems Ltd Sequencing method
US6852492B2 (en) * 2001-09-24 2005-02-08 Intel Corporation Nucleic acid sequencing by raman monitoring of uptake of precursors during molecular replication
US7361313B2 (en) * 2003-02-18 2008-04-22 Intel Corporation Methods for uniform metal impregnation into a nanoporous material
GB0317343D0 (en) 2003-07-24 2003-08-27 Medical Biosystems Ltd Polynucleotide sequencing
US7054528B2 (en) 2004-04-14 2006-05-30 Lucent Technologies Inc. Plasmon-enhanced tapered optical fibers
US7012687B2 (en) 2004-05-04 2006-03-14 Lucent Technologies Inc. Spectral analysis with evanescent field excitation
GB0413082D0 (en) * 2004-06-11 2004-07-14 Medical Biosystems Ltd Method
US7170050B2 (en) 2004-09-17 2007-01-30 Pacific Biosciences Of California, Inc. Apparatus and methods for optical analysis of molecules
WO2006044078A2 (en) 2004-09-17 2006-04-27 Pacific Biosciences Of California, Inc. Apparatus and method for analysis of molecules
CN101415839B (zh) * 2006-02-08 2012-06-27 亿明达剑桥有限公司 对多核苷酸模板进行测序的方法
JP4890926B2 (ja) * 2006-04-28 2012-03-07 キヤノン株式会社 検出方法、およびキット
US7998672B2 (en) 2006-05-30 2011-08-16 The University Of Utah Research Foundation Simultaneous amplification and detection of ribonucleic acid be an optical method using surface plasmon resonance
US8697138B2 (en) 2007-03-28 2014-04-15 Aker Biomarine As Methods of using krill oil to treat risk factors for cardiovascular, metabolic, and inflammatory disorders
EP2134871B1 (de) * 2007-03-30 2012-03-07 Pacific Biosciences of California, Inc. System und verfahren zur verstärkung von fluoreszenzsignalen
JP5222599B2 (ja) * 2007-07-20 2013-06-26 株式会社日立ハイテクノロジーズ 核酸分析デバイス及びそれを用いた核酸分析装置
MX2010003724A (es) * 2007-10-04 2010-09-14 Halcyon Molecular Secuenciacion de polimeros de acido nucleico con microscopia electronica.
JP5175584B2 (ja) * 2008-03-13 2013-04-03 地方独立行政法人 東京都立産業技術研究センター 局所表面プラズモン共鳴イメージング装置
EP3269824A1 (de) 2008-03-28 2018-01-17 Pacific Biosciences Of California, Inc. Zusammensetzungen und verfahren zur nukleinsäuresequenzierung
US9182406B2 (en) 2008-08-04 2015-11-10 Biodesy, Inc. Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability
JP5854350B2 (ja) * 2010-12-08 2016-02-09 公立大学法人大阪府立大学 金属ナノ粒子集積構造体を利用した圧力検出装置、温度検出装置、圧力検出方法、および温度検出方法
US9428789B2 (en) 2011-03-21 2016-08-30 Biodesy, Inc. Classification of kinase inhibitors using nonlinear optical techniques
US9279154B2 (en) 2011-12-21 2016-03-08 Illumina, Inc. Apparatus and methods for kinetic analysis and determination of nucleic acid sequences
US20130288271A1 (en) 2012-04-25 2013-10-31 Biodesy, Llc Methods for detecting allosteric modulators of protein
US9395358B2 (en) 2012-02-05 2016-07-19 Biodesy, Inc. Methods for detecting allosteric modulators of protein
GB2520111A (en) 2012-02-05 2015-05-13 Biodesy Inc Methods for identifying modulators of Ras using nonlinear techniques
US9708656B2 (en) 2013-05-06 2017-07-18 Pacific Biosciences Of California, Inc. Real-time electronic sequencing
EP3936622A1 (de) 2014-06-30 2022-01-12 Bluelight Therapeutics, Inc. Verfahren zur analyse mit hohem durchsatz von konformation in biologischen entitäten
WO2016106286A1 (en) 2014-12-23 2016-06-30 Biodesy, Inc. Attachment of proteins to interfaces for use in nonlinear optical detection
WO2016161386A1 (en) 2015-04-02 2016-10-06 Biodesy, Inc. Methods for determining protein structure using a surface-selective nonlinear optical technique
US10077470B2 (en) 2015-07-21 2018-09-18 Omniome, Inc. Nucleic acid sequencing methods and systems
WO2017014762A1 (en) * 2015-07-21 2017-01-26 Omniome, Inc. Nucleic acid sequencing methods and systems
WO2017196891A1 (en) 2016-05-09 2017-11-16 Biodesy, Inc. Methods and devices for detection of peripheral membrane protein interactions using nonlinear optical techniques
LT3566158T (lt) 2017-01-06 2022-06-27 Illumina, Inc. Fazinė korekcija
KR102246285B1 (ko) * 2017-03-07 2021-04-29 일루미나, 인코포레이티드 단일 광원, 2-광학 채널 서열분석
CN107064106B (zh) * 2017-04-11 2019-07-05 北京航空航天大学 一种二维表面等离子体最佳激发角位置的高精度识别方法
CN110511991A (zh) * 2019-09-11 2019-11-29 胡志刚 大规模dna芯片技术
GB2593729B (en) 2020-03-31 2022-05-11 Perkins Engines Co Ltd Spacer for use in an air intake system of an internal combustion chamber

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US5814516A (en) * 1995-10-13 1998-09-29 Lockheed Martin Energy Systems, Inc. Surface enhanced Raman gene probe and methods thereof
US6072043A (en) * 1996-06-04 2000-06-06 Polyprobe, Inc. Optimally fluorescent oligonucleotides
US5866430A (en) * 1996-06-13 1999-02-02 Grow; Ann E. Raman optrode processes and devices for detection of chemicals and microorganisms
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US5958696A (en) 1997-07-17 1999-09-28 Boehringer Ingelheim Pharmaceuticals, Inc. Quantitative solid phase helicase assay
EP1229133B1 (de) * 1997-07-28 2016-03-09 Gen-Probe Incorporated Apparat zur Nukleinsäuresequenz-Analyse
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US5786389A (en) * 1997-12-28 1998-07-28 Lambert Technologies Inc. Guerbet castor esters
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DE19816202A1 (de) * 1998-04-09 1999-10-14 Karl Seitz Raumkörper zur Errichtung von Bauwerken
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CA2366112A1 (en) 1999-03-10 2000-09-14 Asm Scientific, Inc. A method for direct nucleic acid sequencing
GB9907812D0 (en) * 1999-04-06 1999-06-02 Medical Biosystems Ltd Sequencing
US7056661B2 (en) * 1999-05-19 2006-06-06 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
CA2377722A1 (en) * 1999-07-16 2001-01-25 Wm. Marsh Rice University Metal nanoshells for biosensing applications
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JP2003510065A (ja) * 1999-09-27 2003-03-18 アレイ バイオサイエンス コーポレイション 分析物検出のためのレセプターを有する粒子構造体
GB9923644D0 (en) * 1999-10-06 1999-12-08 Medical Biosystems Ltd DNA sequencing
US6908736B1 (en) * 1999-10-06 2005-06-21 Medical Biosystems, Ltd. DNA sequencing method
EP1358482A1 (de) * 2001-01-08 2003-11-05 Joshua S. Salafsky "verfahren und vorrichtung, die eine oberflächenselektive, nichtlineare optische technik benutzen"
JP2004521323A (ja) * 2001-03-27 2004-07-15 サラフスカイ，ジョシュア，エス． 表面選択的非線形光学技法を使用してプローブ−ターゲット相互作用を検出する方法および装置
GB0112238D0 (en) 2001-05-18 2001-07-11 Medical Biosystems Ltd Sequencing method
GB0317343D0 (en) 2003-07-24 2003-08-27 Medical Biosystems Ltd Polynucleotide sequencing
GB0413082D0 (en) 2004-06-11 2004-07-14 Medical Biosystems Ltd Method

Also Published As

Publication number Publication date
EP1389241A2 (de) 2004-02-18
CA2447222C (en) 2012-09-18
PT1389241E (pt) 2008-04-17
NZ529349A (en) 2006-10-27
CN1537172A (zh) 2004-10-13
JP4907498B2 (ja) 2012-03-28
DK1389241T3 (da) 2008-05-26
JP4094961B2 (ja) 2008-06-04
BR0209841A (pt) 2006-02-07
US20040241678A1 (en) 2004-12-02
WO2002095070A3 (en) 2003-09-18
IL158743A0 (en) 2004-05-12
EP1389241B1 (de) 2008-01-09
GB0112238D0 (en) 2001-07-11
AU2002257933B2 (en) 2006-08-10
CN1537172B (zh) 2013-02-20
JP2008104463A (ja) 2008-05-08
JP2004535800A (ja) 2004-12-02
DE60224524T2 (de) 2009-01-08
IS7039A (is) 2003-11-17
ATE383442T1 (de) 2008-01-15
US20170022556A1 (en) 2017-01-26
RU2003136429A (ru) 2005-05-27
RU2291197C2 (ru) 2007-01-10
US9476094B2 (en) 2016-10-25
WO2002095070A2 (en) 2002-11-28
KR20030094412A (ko) 2003-12-11
ES2299569T3 (es) 2008-06-01
MXPA03010411A (es) 2004-06-25
CA2447222A1 (en) 2002-11-28
US20090029383A1 (en) 2009-01-29
HK1061047A1 (en) 2004-09-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee