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DE60137452D1 - Pulverzubereitungen und verfahren zu ihrer herstellung - Google Patents

Pulverzubereitungen und verfahren zu ihrer herstellung

Info

Publication number
DE60137452D1
DE60137452D1 DE60137452T DE60137452T DE60137452D1 DE 60137452 D1 DE60137452 D1 DE 60137452D1 DE 60137452 T DE60137452 T DE 60137452T DE 60137452 T DE60137452 T DE 60137452T DE 60137452 D1 DE60137452 D1 DE 60137452D1
Authority
DE
Germany
Prior art keywords
production
particle diameter
powder preparations
formulation
medicament
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60137452T
Other languages
English (en)
Inventor
Satomi Onoue
Kousuke Endo
Kazuhisa Kashimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ILS Inc
Original Assignee
Itoham Foods Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2001088337A external-priority patent/JP2002284703A/ja
Application filed by Itoham Foods Inc filed Critical Itoham Foods Inc
Priority claimed from JP2001364325A external-priority patent/JP4125512B2/ja
Application granted granted Critical
Publication of DE60137452D1 publication Critical patent/DE60137452D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE60137452T 2000-11-29 2001-11-29 Pulverzubereitungen und verfahren zu ihrer herstellung Expired - Lifetime DE60137452D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2000362704 2000-11-29
JP2001088337A JP2002284703A (ja) 2001-03-26 2001-03-26 粉末製剤
JP2001364325A JP4125512B2 (ja) 2000-11-29 2001-11-29 粉末製剤及びその製造方法
PCT/JP2001/010445 WO2002043703A1 (fr) 2000-11-29 2001-11-29 Preparations pulverulentes et son procede de production

Publications (1)

Publication Number Publication Date
DE60137452D1 true DE60137452D1 (de) 2009-03-05

Family

ID=27345297

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60137452T Expired - Lifetime DE60137452D1 (de) 2000-11-29 2001-11-29 Pulverzubereitungen und verfahren zu ihrer herstellung

Country Status (10)

Country Link
US (1) US20040109827A1 (de)
EP (1) EP1348428B1 (de)
KR (1) KR100587237B1 (de)
CN (1) CN100400031C (de)
AT (1) ATE420630T1 (de)
AU (2) AU1850302A (de)
CA (1) CA2430318C (de)
DE (1) DE60137452D1 (de)
HK (1) HK1063286A1 (de)
WO (1) WO2002043703A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060171899A1 (en) * 1998-12-10 2006-08-03 Akwete Adjei Water-stabilized aerosol formulation system and method of making
AU2003220125B2 (en) 2002-03-20 2006-06-15 Mannkind Corporation Inhalation apparatus
GB0327723D0 (en) 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
DK3520779T3 (da) 2004-04-23 2022-03-21 Cydex Pharmaceuticals Inc DPI formulering indeholdende sulfoalkylethercyclodextrin
EP1593376A1 (de) * 2004-05-04 2005-11-09 Warner-Lambert Company LLC Verbesserte Pullulankapseln
DE602005024413D1 (de) 2004-08-20 2010-12-09 Mannkind Corp Katalyse der diketopiperazinsynthese
EP2322180B1 (de) 2004-08-23 2015-05-27 MannKind Corporation Diketopiperazinsalze zur Arzneimitteldarreichung
CN101155590A (zh) * 2005-02-10 2008-04-02 葛兰素集团有限公司 使用预分选技术制备乳糖的方法以及由此形成的药物制剂
CN102614131A (zh) 2005-09-14 2012-08-01 曼金德公司 以提高结晶微粒表面对活性试剂的亲和力为基础的药物配制方法
US7629331B2 (en) 2005-10-26 2009-12-08 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
BRPI0707991B8 (pt) 2006-02-22 2021-05-25 Mannkind Corp métodos de preparação de um medicamento em pó seco com uma propriedade farmacêutica melhorada, dito pó seco e uso de uma quantidade efetiva do pó seco
DE102006053375A1 (de) * 2006-11-10 2008-05-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Mischung von Pulvern
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
IL313823A (en) 2008-06-13 2024-08-01 Mannkind Corp A dry powder inhaler and system for drug delivery
AU2009259883B2 (en) 2008-06-20 2015-02-05 Mannkind Corporation An interactive apparatus and method for real-time profiling of inhalation efforts
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
KR20130117755A (ko) 2010-06-21 2013-10-28 맨카인드 코포레이션 건조 분말 약물 운반 시스템 및 방법
MX353285B (es) 2011-04-01 2018-01-05 Mannkind Corp Paquete de blister para cartuchos farmaceuticos.
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
SG11201400580VA (en) * 2011-09-14 2014-05-29 Shionogi & Co Pharmaceutical composition for inhalation
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
JP5087182B1 (ja) * 2012-06-13 2012-11-28 クリニプロ株式会社 吸入用パウダーの製造方法
BR112015000529B1 (pt) 2012-07-12 2022-01-11 Mannkind Corporation Inalador de pó seco
WO2014145720A2 (en) * 2013-03-15 2014-09-18 Antioxidant Superfoods, Inc. Fat emulsion providing taste masking for active health and wellness ingredients
BR112016000937A8 (pt) * 2013-07-18 2021-06-22 Mannkind Corp formulações farmacêuticas de pó seco, método para a fabricação de uma formulação de pó seco e uso de uma formulação farmacêutica de pó seco
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
TWI745396B (zh) 2016-07-12 2021-11-11 日商鹽野義製藥股份有限公司 吸入用醫藥組成物
WO2019102310A1 (en) * 2017-11-24 2019-05-31 Alaval (Pty) Ltd Vip formulation for management of inflammatory conditions

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9100009D0 (en) * 1991-01-02 1991-02-20 Cerestar Holding Bv Erythritol compositions
US5354934A (en) * 1993-02-04 1994-10-11 Amgen Inc. Pulmonary administration of erythropoietin
CA2155933C (en) * 1993-02-12 2000-04-04 James L. Levin Pulmonary administration of scr1 and other complement inhibitory proteins
RU2143889C1 (ru) * 1993-02-23 2000-01-10 Генентек, Инк. Способ стабилизации полипептида, способы получения композиций полипептида и композиции
TW402506B (en) * 1993-06-24 2000-08-21 Astra Ab Therapeutic preparation for inhalation
CZ295827B6 (cs) * 1994-03-07 2005-11-16 Nektar Therapeutics Způsob aerosolizace dávky inzulinu, inzulinový přípravek a jeho použití
JPH08301762A (ja) * 1995-05-12 1996-11-19 Teijin Ltd 肺癌治療剤
JPH08337532A (ja) * 1995-06-14 1996-12-24 Takeda Chem Ind Ltd 医薬組成物
DE69724272T3 (de) * 1996-02-27 2007-05-10 Teijin Ltd. Puderförmige zusammensetzung zur nasalen anwendung
US5898028A (en) * 1997-03-20 1999-04-27 Novo Nordisk A/S Method for producing powder formulation comprising an insulin
JP4266399B2 (ja) * 1997-12-04 2009-05-20 帝人株式会社 粉末状吸入用医薬品組成物
JP4691298B2 (ja) * 1999-10-12 2011-06-01 科研製薬株式会社 粉末吸入用製剤及びその製造方法

Also Published As

Publication number Publication date
ATE420630T1 (de) 2009-01-15
WO2002043703A1 (fr) 2002-06-06
CA2430318A1 (en) 2002-06-06
CN1486175A (zh) 2004-03-31
AU1850302A (en) 2002-06-11
EP1348428B1 (de) 2009-01-14
CN100400031C (zh) 2008-07-09
AU2002218503B2 (en) 2006-09-28
HK1063286A1 (en) 2004-12-24
KR100587237B1 (ko) 2006-06-07
CA2430318C (en) 2009-10-27
EP1348428A1 (de) 2003-10-01
KR20030096238A (ko) 2003-12-24
EP1348428A4 (de) 2005-09-21
US20040109827A1 (en) 2004-06-10

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: ILS INC., MORIYA-SHI, IBARAKI, JP

8364 No opposition during term of opposition