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PL308838A1 - Pharmaceutical preparation containing cefixim as its active substance and method of stabilising such preparations - Google Patents

Pharmaceutical preparation containing cefixim as its active substance and method of stabilising such preparations

Info

Publication number
PL308838A1
PL308838A1 PL95308838A PL30883895A PL308838A1 PL 308838 A1 PL308838 A1 PL 308838A1 PL 95308838 A PL95308838 A PL 95308838A PL 30883895 A PL30883895 A PL 30883895A PL 308838 A1 PL308838 A1 PL 308838A1
Authority
PL
Poland
Prior art keywords
cefixim
stabilising
preparations
active substance
pharmaceutical preparation
Prior art date
Application number
PL95308838A
Inventor
Joachim Bolz
Gertraud Wagner
Eckhard Oelrich
Dirk Radtke
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PL308838A1 publication Critical patent/PL308838A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Readily re-dispersible and chemically stable cefixime prepns. in the form of non-aq. suspensions having a syrup-like consistency and being free from thickeners are claimed. The suspensions conveniently contain a finely powdered (micronised) filler, with at least 80 wt.% of the particles having a max. diameter of 32 micron and a max. 5 wt.% of the particles having a diameter above 50 micron.
PL95308838A 1994-05-31 1995-05-30 Pharmaceutical preparation containing cefixim as its active substance and method of stabilising such preparations PL308838A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4418957A DE4418957A1 (en) 1994-05-31 1994-05-31 Cefixime preparation

Publications (1)

Publication Number Publication Date
PL308838A1 true PL308838A1 (en) 1995-12-11

Family

ID=6519407

Family Applications (1)

Application Number Title Priority Date Filing Date
PL95308838A PL308838A1 (en) 1994-05-31 1995-05-30 Pharmaceutical preparation containing cefixim as its active substance and method of stabilising such preparations

Country Status (25)

Country Link
US (1) US5776926A (en)
EP (1) EP0685232B1 (en)
JP (1) JPH07330607A (en)
KR (1) KR950031077A (en)
CN (1) CN1117383A (en)
AT (1) ATE190844T1 (en)
AU (1) AU694201B2 (en)
CA (1) CA2150442A1 (en)
CO (1) CO4410174A1 (en)
CZ (1) CZ138595A3 (en)
DE (2) DE4418957A1 (en)
DK (1) DK0685232T3 (en)
ES (1) ES2146265T3 (en)
FI (1) FI952629A (en)
GR (1) GR3033704T3 (en)
HU (1) HU218217B (en)
IL (1) IL113917A0 (en)
NO (1) NO952138L (en)
NZ (1) NZ272216A (en)
PE (1) PE18796A1 (en)
PL (1) PL308838A1 (en)
PT (1) PT685232E (en)
SK (1) SK72795A3 (en)
TW (1) TW301610B (en)
ZA (1) ZA954427B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE216887T1 (en) * 1996-02-29 2002-05-15 Fujisawa Pharmaceutical Co TABLETS CONTAINING BETA-LACTAM ANTIBIOTIC AND METHOD FOR THE PRODUCTION THEREOF
TW200404550A (en) * 2002-07-08 2004-04-01 Sankyo Co Cepharospolin formulation for oral use
WO2005107703A1 (en) * 2004-05-10 2005-11-17 Lupin Ltd. Novel pharmaceutical formulation of cefixime for enhanced bioavailability
DE112007000920T5 (en) 2006-04-13 2009-02-12 Lupin Ltd., Mumbai Pharmaceutical compositions of cefixime
US9233112B2 (en) 2006-04-13 2016-01-12 Lupin Limited Pharmaceutical compositions of cefixime
CN103301068B (en) * 2013-07-08 2014-09-10 广东彼迪药业有限公司 Cefixime dry suspension and preparation method thereof
JP6449873B2 (en) * 2013-07-18 2019-01-09 サンド・アクチエンゲゼルシヤフト Powder mixture for antibiotic dry syrup formulations
US11446236B2 (en) 2015-08-05 2022-09-20 Cmpd Licensing, Llc Topical antimicrobial compositions and methods of formulating the same
US11173163B2 (en) * 2015-08-05 2021-11-16 Cmpd Licensing, Llc Topical antimicrobial compositions and methods of formulating the same
US11684567B2 (en) 2015-08-05 2023-06-27 Cmpd Licensing, Llc Compositions and methods for treating an infection
US11793783B2 (en) 2015-08-05 2023-10-24 Cmpd Licensing, Llc Compositions and methods for treating an infection

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996355A (en) 1975-01-02 1976-12-07 American Home Products Corporation Permanent suspension pharmaceutical dosage form
DE3804841A1 (en) * 1988-02-17 1989-08-31 Hoechst Ag CEPHALOSPORINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION
US5409917A (en) * 1991-03-05 1995-04-25 Marvin S. Towsend Topical treatment of acne with cephalosporins

Also Published As

Publication number Publication date
US5776926A (en) 1998-07-07
HUT74421A (en) 1996-12-30
SK72795A3 (en) 1996-01-10
DK0685232T3 (en) 2000-08-21
AU2033595A (en) 1995-12-07
PT685232E (en) 2000-08-31
GR3033704T3 (en) 2000-10-31
ZA954427B (en) 1996-01-24
HU218217B (en) 2000-06-28
EP0685232A3 (en) 1996-05-08
JPH07330607A (en) 1995-12-19
ATE190844T1 (en) 2000-04-15
DE4418957A1 (en) 1995-12-07
DE59508024D1 (en) 2000-04-27
CO4410174A1 (en) 1997-01-09
ES2146265T3 (en) 2000-08-01
CA2150442A1 (en) 1995-12-01
EP0685232B1 (en) 2000-03-22
AU694201B2 (en) 1998-07-16
TW301610B (en) 1997-04-01
HU9501570D0 (en) 1995-07-28
NZ272216A (en) 1996-05-28
FI952629A (en) 1995-12-01
PE18796A1 (en) 1996-06-04
NO952138D0 (en) 1995-05-30
NO952138L (en) 1995-12-01
CZ138595A3 (en) 1996-04-17
CN1117383A (en) 1996-02-28
KR950031077A (en) 1995-12-18
EP0685232A2 (en) 1995-12-06
FI952629A0 (en) 1995-05-30
IL113917A0 (en) 1995-08-31

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