DE60128902D1 - Formulierungen zur verwendung in inhalationsvorrichtungen - Google Patents
Formulierungen zur verwendung in inhalationsvorrichtungenInfo
- Publication number
- DE60128902D1 DE60128902D1 DE60128902T DE60128902T DE60128902D1 DE 60128902 D1 DE60128902 D1 DE 60128902D1 DE 60128902 T DE60128902 T DE 60128902T DE 60128902 T DE60128902 T DE 60128902T DE 60128902 D1 DE60128902 D1 DE 60128902D1
- Authority
- DE
- Germany
- Prior art keywords
- formulations
- diameter
- inhalation devices
- formulation
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000010419 fine particle Substances 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0009468.0A GB0009468D0 (en) | 2000-04-17 | 2000-04-17 | Improvements in or relating to formulations for use in inhaler devices |
GB0009468 | 2000-04-17 | ||
EP00113608 | 2000-06-27 | ||
EP00113608 | 2000-06-27 | ||
PCT/GB2001/001757 WO2001078696A2 (en) | 2000-04-17 | 2001-04-17 | Formulations for use in inhaler devices |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60128902D1 true DE60128902D1 (de) | 2007-07-26 |
DE60128902T2 DE60128902T2 (de) | 2008-02-14 |
Family
ID=26071083
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60128902T Expired - Lifetime DE60128902T2 (de) | 2000-04-17 | 2001-04-17 | Formulierungen zur verwendung in inhalationsvorrichtungen |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1276474B1 (de) |
JP (1) | JP2004500424A (de) |
AT (1) | ATE364381T1 (de) |
AU (1) | AU782841B2 (de) |
CA (1) | CA2406206C (de) |
DE (1) | DE60128902T2 (de) |
ES (1) | ES2288167T3 (de) |
NZ (1) | NZ521972A (de) |
WO (1) | WO2001078696A2 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
US7094545B2 (en) | 2003-04-30 | 2006-08-22 | Ferring Bv | Pharmaceutical composition as solid dosage form and method for manufacturing thereof |
EP1500390B1 (de) | 2003-07-25 | 2005-08-17 | Ferring B.V. | Pharmazeutische Desmopressin-Zubereitung als feste Darreichungsform und Methode zu ihrer Herstellung |
US7018653B2 (en) | 2003-12-29 | 2006-03-28 | Ferring B.V. | Method for preparing solid dosage form of desmopressin |
GB0425758D0 (en) | 2004-11-23 | 2004-12-22 | Vectura Ltd | Preparation of pharmaceutical compositions |
GB0714134D0 (en) * | 2007-07-19 | 2007-08-29 | Norton Healthcare Ltd | Dry-powder medicament |
CA2693377A1 (en) | 2007-07-21 | 2009-01-29 | Albany Molecular Research, Inc. | 5-pyridinone substituted indazoles |
US20090324569A1 (en) | 2007-11-21 | 2009-12-31 | Decode Genetics Ehf | Biaryl pde4 inhibitors for treating inflammatory, cardiovascular and cns disorders |
EP2476680B1 (de) | 2008-01-11 | 2014-08-27 | Albany Molecular Research, Inc. | (1-Azinon)-substituierte Pyrido-Indole |
WO2010059836A1 (en) | 2008-11-20 | 2010-05-27 | Decode Genetics Ehf | Substituted aza-bridged bicyclics for cardiovascular and cns disease |
TWI491416B (zh) | 2008-12-24 | 2015-07-11 | Daiichi Sankyo Co Ltd | 吸入用乾燥粉末醫藥組成物 |
NZ594768A (en) | 2009-01-26 | 2013-02-22 | Israel Inst Biolog Res | Bicyclic heterocyclic spiro compounds |
JP2012520890A (ja) * | 2009-03-18 | 2012-09-10 | インカーダ セラピューティクス, インコーポレイテッド | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
WO2014152531A1 (en) | 2013-03-15 | 2014-09-25 | 3D Systems, Inc. | Three dimensional printing material system |
GB201305825D0 (en) | 2013-03-28 | 2013-05-15 | Vectura Ltd | New use |
MX392636B (es) | 2014-10-31 | 2025-03-24 | Glaxosmithkline Ip Dev Ltd | Formulacion en polvo. |
SG11201805788WA (en) | 2016-02-01 | 2018-08-30 | Incarda Therapeutics Inc | Combining electronic monitoring with inhaled pharmacological therapy to manage cardiac arrhythmias including atrial fibrillation |
EP3768267A4 (de) | 2018-03-20 | 2022-04-20 | Icahn School of Medicine at Mount Sinai | Kinaseinhibitorverbindungen und zusammensetzungen und verfahren zur verwendung |
US10744087B2 (en) | 2018-03-22 | 2020-08-18 | Incarda Therapeutics, Inc. | Method to slow ventricular rate |
US10966943B2 (en) | 2018-09-06 | 2021-04-06 | Innopharmascreen Inc. | Methods and compositions for treatment of asthma or parkinson's disease |
AU2019419414A1 (en) | 2018-12-31 | 2023-04-06 | Icahn School Of Medicine At Mount Sinai | Kinase inhibitor compounds and compositions and methods of use |
US11020384B2 (en) | 2019-08-01 | 2021-06-01 | Incarda Therapeutics, Inc. | Antiarrhythmic formulation |
GB2633305A (en) | 2023-08-30 | 2025-03-12 | Envirohale Malta Holdings Ltd | Nasal and pulmonary drug delivery |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4349542A (en) * | 1979-06-08 | 1982-09-14 | National Research Development Corporation | Mixture containing active ingredient and dendritic crystalline sugar for tableting |
DE4140689B4 (de) * | 1991-12-10 | 2007-11-22 | Boehringer Ingelheim Kg | Inhalationspulver und Verfahren zu ihrer Herstellung |
GB9322014D0 (en) * | 1993-10-26 | 1993-12-15 | Co Ordinated Drug Dev | Improvements in and relating to carrier particles for use in dry powder inhalers |
DE4425255A1 (de) * | 1994-07-16 | 1996-01-18 | Asta Medica Ag | Formulierung zur inhalativen Applikation |
GB9501841D0 (en) * | 1995-01-31 | 1995-03-22 | Co Ordinated Drug Dev | Improvements in and relating to carrier particles for use in dry powder inhalers |
US6645466B1 (en) * | 1998-11-13 | 2003-11-11 | Jago Research Ag | Dry powder for inhalation |
-
2001
- 2001-04-17 AU AU48601/01A patent/AU782841B2/en not_active Ceased
- 2001-04-17 CA CA2406206A patent/CA2406206C/en not_active Expired - Fee Related
- 2001-04-17 ES ES01921631T patent/ES2288167T3/es not_active Expired - Lifetime
- 2001-04-17 AT AT01921631T patent/ATE364381T1/de active
- 2001-04-17 WO PCT/GB2001/001757 patent/WO2001078696A2/en active IP Right Grant
- 2001-04-17 NZ NZ521972A patent/NZ521972A/en not_active IP Right Cessation
- 2001-04-17 JP JP2001575997A patent/JP2004500424A/ja active Pending
- 2001-04-17 DE DE60128902T patent/DE60128902T2/de not_active Expired - Lifetime
- 2001-04-17 EP EP01921631A patent/EP1276474B1/de not_active Revoked
Also Published As
Publication number | Publication date |
---|---|
AU782841B2 (en) | 2005-09-01 |
EP1276474B1 (de) | 2007-06-13 |
EP1276474A2 (de) | 2003-01-22 |
CA2406206C (en) | 2012-03-20 |
NZ521972A (en) | 2004-06-25 |
WO2001078696A2 (en) | 2001-10-25 |
ATE364381T1 (de) | 2007-07-15 |
CA2406206A1 (en) | 2001-10-25 |
JP2004500424A (ja) | 2004-01-08 |
ES2288167T3 (es) | 2008-01-01 |
AU4860101A (en) | 2001-10-30 |
WO2001078696A3 (en) | 2002-03-14 |
DE60128902T2 (de) | 2008-02-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent |