DE60030859D1 - Gruppen von borrelia burgdorferi, die lyme krankheit verursachen - Google Patents
Gruppen von borrelia burgdorferi, die lyme krankheit verursachenInfo
- Publication number
- DE60030859D1 DE60030859D1 DE60030859T DE60030859T DE60030859D1 DE 60030859 D1 DE60030859 D1 DE 60030859D1 DE 60030859 T DE60030859 T DE 60030859T DE 60030859 T DE60030859 T DE 60030859T DE 60030859 D1 DE60030859 D1 DE 60030859D1
- Authority
- DE
- Germany
- Prior art keywords
- lyme disease
- creating
- groups
- ospc
- borrelia burgdorferi
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 208000016604 Lyme disease Diseases 0.000 title abstract 3
- 241000589969 Borreliella burgdorferi Species 0.000 title 1
- 108700023315 OspC Proteins 0.000 abstract 5
- 230000002163 immunogen Effects 0.000 abstract 5
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 239000012634 fragment Substances 0.000 abstract 2
- 241000589968 Borrelia Species 0.000 abstract 1
- 101100135142 Borrelia burgdorferi ospC gene Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0225—Spirochetes, e.g. Treponema, Leptospira, Borrelia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Mycology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14004299P | 1999-06-18 | 1999-06-18 | |
US140042P | 1999-06-18 | ||
PCT/US2000/016915 WO2000078966A1 (en) | 1999-06-18 | 2000-06-19 | Groups of borrelia burgdorferi and borrelia afzelii that cause lyme disease in humans |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60030859D1 true DE60030859D1 (de) | 2006-11-02 |
DE60030859T2 DE60030859T2 (de) | 2007-06-14 |
Family
ID=22489483
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60030859T Expired - Lifetime DE60030859T2 (de) | 1999-06-18 | 2000-06-19 | Gruppen von borrelia burgdorferi, die lyme krankheit verursachen |
Country Status (9)
Country | Link |
---|---|
US (2) | US7060281B1 (de) |
EP (2) | EP1683867B1 (de) |
AT (1) | ATE340262T1 (de) |
AU (1) | AU5751000A (de) |
DE (1) | DE60030859T2 (de) |
DK (1) | DK1194559T3 (de) |
ES (1) | ES2272296T3 (de) |
PT (1) | PT1194559E (de) |
WO (1) | WO2000078966A1 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1194559T3 (da) * | 1999-06-18 | 2007-02-05 | Univ New York State Res Found | Grupper af Borrelia burgdorferi, som forårsager Lyme sygdom hos mennesker |
EP1939294A1 (de) | 2000-08-18 | 2008-07-02 | Research Foundation Of State University Of New York | Rekombinante Konstrukte von Borrelia Burgdorferi |
GB2414667A (en) * | 2004-06-03 | 2005-12-07 | Isis Innovation | Vaccine compositions of N. meningitidis PorA and FetA antigens |
US8821893B2 (en) * | 2004-07-02 | 2014-09-02 | Bio Peptides, Corp. | Oral vaccine for Borrelia |
EP1957520A4 (de) * | 2005-11-29 | 2009-05-27 | Univ Virginia Commonwealth | Polyvalentes chimärisches ospc-vaccinogen und diagnostisches antigen |
KR102428294B1 (ko) | 2006-01-19 | 2022-08-01 | 마리 케이 인코포레이티드 | 카카두 플럼 추출물 또는 아카이 베리 추출물을 포함하는 조성물 |
WO2008116468A2 (en) | 2007-03-26 | 2008-10-02 | Dako Denmark A/S | Mhc peptide complexes and uses thereof in infectious diseases |
WO2009003493A2 (en) | 2007-07-03 | 2009-01-08 | Dako Denmark A/S | Mhc multimers, methods for their generation, labeling and use |
US10611818B2 (en) | 2007-09-27 | 2020-04-07 | Agilent Technologies, Inc. | MHC multimers in tuberculosis diagnostics, vaccine and therapeutics |
US10968269B1 (en) | 2008-02-28 | 2021-04-06 | Agilent Technologies, Inc. | MHC multimers in borrelia diagnostics and disease |
JP2011518338A (ja) | 2008-04-22 | 2011-06-23 | リサーチ ファンデーション オブ ステート ユニバーシティ オブ ニューヨーク | ボレリア・ブルグドルフェリ(borreliaburgdorferi)の細胞エンベロープタンパク質のアレイ |
WO2010009735A2 (en) | 2008-07-23 | 2010-01-28 | Dako Denmark A/S | Combinatorial analysis and repair |
GB0817244D0 (en) | 2008-09-20 | 2008-10-29 | Univ Cardiff | Use of a protein kinase inhibitor to detect immune cells, such as T cells |
WO2010037402A1 (en) | 2008-10-02 | 2010-04-08 | Dako Denmark A/S | Molecular vaccines for infectious disease |
US11992518B2 (en) | 2008-10-02 | 2024-05-28 | Agilent Technologies, Inc. | Molecular vaccines for infectious disease |
WO2010132758A2 (en) * | 2009-05-14 | 2010-11-18 | Gomes-Solecki Maria J | Ospc-based diagnostic test for lyme disease |
FR2949472B1 (fr) * | 2009-08-28 | 2013-08-09 | Biomerieux Sa | Proteines utilisees pour le diagnostic d'une borreliose de lyme |
EA023290B1 (ru) | 2009-08-28 | 2016-05-31 | Мэри Кей Инк. | Косметический способ и топическая композиция для омоложения, регенерации и упрочнения кожи во время сна |
US20160097768A1 (en) | 2010-10-20 | 2016-04-07 | Virginia Commonwealth University | Polyvalent chimeric ospc vaccinogen and diagnostic antigen |
CN103339151A (zh) * | 2010-10-20 | 2013-10-02 | 弗吉尼亚联邦大学 | 多价嵌合OspC疫苗原和诊断抗原 |
WO2013067448A2 (en) | 2011-11-03 | 2013-05-10 | Vca Antech Inc. | Compositions and methods to detect various infectious organisms |
EP2809348B1 (de) * | 2012-02-01 | 2018-11-07 | Biopeptides Corporation | Diagnostische peptide für lyme-borreliose |
US9562079B2 (en) | 2012-04-18 | 2017-02-07 | Zoetis Services Llc | Vaccines and methods to treat lyme disease in dogs |
RU2514230C1 (ru) * | 2012-12-14 | 2014-04-27 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт биохимии" Сибирского отделения Российской академии медицинских наук (ФГБУ "НИИ биохимии" СО РАМН) | Рекомбинантные химерные полипептиды, несущие эпитопы различных иммунодоминантных белков спирохет комплекса borrelia burgdorferi sensu lato, и способ серодиагностики иксодового клещевого боррелиоза |
CA2963643A1 (en) | 2014-10-07 | 2016-04-14 | The Research Foundation For The State University Of New York | Recombinant borrelia proteins and methods of use thereof |
US11209431B2 (en) | 2015-10-06 | 2021-12-28 | Bio-Rad Laboratories, Inc. | Borrelia immunoassays and materials therefor |
WO2025015042A1 (en) | 2023-07-10 | 2025-01-16 | Dynavax Technologies Corporation | Lyme disease vaccines comprising an adjuvant and a borrelia outer surface protein a antigen |
WO2025015077A1 (en) | 2023-07-10 | 2025-01-16 | Dynavax Technologies Corporation | Lyme disease vaccines comprising an adjuvant and borrelia outer surface protein a and c antigens |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5646016A (en) * | 1991-02-06 | 1997-07-08 | Genetics Institute, Inc. | Peptide and protein fusions to thioredoxin, thioredoxin-like molecules, and modified thioredoxin-like molecules |
US6221363B1 (en) | 1991-07-11 | 2001-04-24 | Baxter Aktiengesellschaft | Vaccine for the prevention of lyme disease |
EP0686265A4 (de) | 1993-02-26 | 2001-08-22 | Cambridge Biotech Corp | Verfahren zum induzieren von immunität gegen die lyme-krankheit und ein kolorimetrischer test auf borreliazide aktivität von antisera |
AU683260B2 (en) | 1993-04-29 | 1997-11-06 | Immuno Aktiengesellschaft | Immunogenic formulation of OspC antigen vaccines for the prevention and treatment of lyme disease and recombinant methods for the preparation of such antigens |
CA2175567C (en) * | 1993-11-01 | 2010-08-10 | John J. Dunn | Chimeric proteins comprising borrelia polypeptides: uses therefor |
AU2207195A (en) * | 1994-04-05 | 1995-10-23 | Board Of Regents, The University Of Texas System | Modified receptors that continuously signal |
AR003941A1 (es) * | 1995-04-19 | 1998-09-30 | Polymun Scient Immunbilogische Forschung Gmbh | Anticuerpos monoclonales humanos neutralizadores de hiv-1 |
US5804427A (en) * | 1995-05-19 | 1998-09-08 | University Of Massachusetts | Cytokine-, stress-, and oncoprotein-activated human protein kinase kinases |
US5683903A (en) * | 1995-05-30 | 1997-11-04 | Smithkline Beecham Corporation | Attachment enhanced 293 cells |
US6251405B1 (en) | 1995-06-07 | 2001-06-26 | Connaught Laboratories, Inc. | Immunological combination compositions and methods |
US5849891A (en) * | 1995-07-28 | 1998-12-15 | National Science Council | Satellite RNA from bamboo mosaic virus as a vector for foreign gene expression in plants |
GB9517585D0 (en) * | 1995-08-29 | 1995-11-01 | Cookson William O C | Atopy diagnosis and therapy |
US5756294A (en) * | 1995-09-25 | 1998-05-26 | Oncormed, Inc. | Susceptibility mutation for breast and ovarian cancer |
GB9526218D0 (en) * | 1995-12-21 | 1996-02-21 | Gene Shears Pty Ltd | DNA Sequences |
US6255464B1 (en) * | 1996-04-18 | 2001-07-03 | The Johns Hopkins University | Mad-related genes in the human |
DK0896583T3 (da) | 1996-05-02 | 2003-05-26 | Dako As | Anvendelse af peptidfragmenter fra OspC til diagnostiske metoder |
US6110703A (en) * | 1996-07-05 | 2000-08-29 | Novo Nordisk A/S | Method for the production of polypeptides |
US5824318A (en) * | 1996-07-24 | 1998-10-20 | American Cyanamid Company | Avirulent herpetic viruses useful as tumoricidal agents and vaccines |
JP4108755B2 (ja) * | 1996-09-11 | 2008-06-25 | 大日本住友製薬株式会社 | 新規セマフォリン遺伝子:セマフォリンy |
US6131578A (en) * | 1996-10-02 | 2000-10-17 | King; George L. | Inhibitors of UDP-G1cNAc:Ga1β1-3Ga1NAcαR β1-6 N-acetylglucosaminyltransferase (core 2 G1cNAc-T) and use of the inhibitors to prevent or treat cardiomyopathy associated with diabetes |
CA2283193A1 (en) | 1997-03-11 | 1998-09-17 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
US6420108B2 (en) * | 1998-02-09 | 2002-07-16 | Affymetrix, Inc. | Computer-aided display for comparative gene expression |
DE19740735A1 (de) | 1997-09-16 | 1999-03-18 | Max Planck Gesellschaft | Arzneimittel zur Therapie einer manifesten Lyme-Borreliose |
US6194556B1 (en) * | 1997-12-11 | 2001-02-27 | Millennium Pharmaceuticals, Inc. | Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therfor |
US6150081A (en) * | 1997-12-24 | 2000-11-21 | Fuji Photo Film B.V. | Silver halide emulsions with recombinant collagen suitable for photographic application and also the preparation thereof |
AU762378B2 (en) * | 1998-02-17 | 2003-06-26 | Bristol-Myers Squibb Company | Members of the D52 gene family |
BR9909280A (pt) * | 1998-04-01 | 2000-11-21 | Danisco | Exoamilases não maltogênicas e sua utilização no retardo de retrogradação de amido |
US6245525B1 (en) * | 1998-07-27 | 2001-06-12 | Ludwig Institute For Cancer Research | Tumor associated nucleic acids and uses therefor |
US6248937B1 (en) * | 1998-04-27 | 2001-06-19 | The Regents Of The University Of California | Transcription factor and method for regulation of seed development, quality and stress-tolerance |
JP3631960B2 (ja) | 1998-07-31 | 2005-03-23 | ガンダーセン ルテラン メディカル ファウンデイション インコーポレイテッド | ワクチンとしてのボレリアブルグドルフェリ外部表面タンパク質c(ospc)のボレリアシダルエピトープの使用 |
US6627193B1 (en) * | 1999-01-13 | 2003-09-30 | University Of Georgia Research Foundation, Inc. | Methods and compositions for control of blood coagulation |
US6468773B1 (en) * | 1999-05-19 | 2002-10-22 | Genencor International, Inc. | Mutant 1,3-propandiol dehydrogenase |
DK1194559T3 (da) * | 1999-06-18 | 2007-02-05 | Univ New York State Res Found | Grupper af Borrelia burgdorferi, som forårsager Lyme sygdom hos mennesker |
AU6611900A (en) * | 1999-07-30 | 2001-03-13 | Agy Therapeutics, Inc. | Techniques for facilitating identification of candidate genes |
US6472154B1 (en) * | 1999-12-31 | 2002-10-29 | Board Of Regents, The University Of Texas System | Polymorphic repeats in human genes |
US6337208B1 (en) * | 2000-01-03 | 2002-01-08 | Stefan Graupner | Cloning vector |
-
2000
- 2000-06-19 DK DK00942966T patent/DK1194559T3/da active
- 2000-06-19 EP EP05019066.9A patent/EP1683867B1/de not_active Expired - Lifetime
- 2000-06-19 US US09/596,746 patent/US7060281B1/en not_active Expired - Lifetime
- 2000-06-19 ES ES00942966T patent/ES2272296T3/es not_active Expired - Lifetime
- 2000-06-19 AU AU57510/00A patent/AU5751000A/en not_active Abandoned
- 2000-06-19 EP EP00942966A patent/EP1194559B1/de not_active Expired - Lifetime
- 2000-06-19 PT PT00942966T patent/PT1194559E/pt unknown
- 2000-06-19 DE DE60030859T patent/DE60030859T2/de not_active Expired - Lifetime
- 2000-06-19 AT AT00942966T patent/ATE340262T1/de active
- 2000-06-19 WO PCT/US2000/016915 patent/WO2000078966A1/en active IP Right Grant
-
2006
- 2006-03-09 US US11/371,564 patent/US7582304B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20090060932A2 (en) | 2009-03-05 |
DK1194559T3 (da) | 2007-02-05 |
US20060182756A1 (en) | 2006-08-17 |
DE60030859T2 (de) | 2007-06-14 |
AU5751000A (en) | 2001-01-09 |
ATE340262T1 (de) | 2006-10-15 |
EP1194559B1 (de) | 2006-09-20 |
WO2000078966A1 (en) | 2000-12-28 |
EP1194559A1 (de) | 2002-04-10 |
US7582304B2 (en) | 2009-09-01 |
EP1683867A1 (de) | 2006-07-26 |
PT1194559E (pt) | 2007-01-31 |
ES2272296T3 (es) | 2007-05-01 |
EP1683867B1 (de) | 2014-04-09 |
US7060281B1 (en) | 2006-06-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |