DE60030002D1 - Für adenosin a3, a2a und a3 rezeptoren spezifische verbindungen und deren verwendungen - Google Patents

Für adenosin a3, a2a und a3 rezeptoren spezifische verbindungen und deren verwendungen

Info

Publication number: DE60030002D1
Authority: DE; Germany
Prior art keywords: adenosine; specific compounds; compounds; receptors specific; receptors
Prior art date: 1999-12-02
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60030002T

Other languages

English (en)

Other versions

DE60030002T2 (de

Inventor

L Castelhano

Bryan Mckibben

J Witter

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

OSI Pharmaceuticals LLC

Original Assignee

OSI Pharmaceuticals LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-12-02

Filing date

2000-12-01

Publication date

2006-09-21

1999-12-02 Priority claimed from US09/454,074 external-priority patent/US6878716B1/en

1999-12-02 Priority claimed from US09/454,075 external-priority patent/US6686366B1/en

2000-12-01 Application filed by OSI Pharmaceuticals LLC filed Critical OSI Pharmaceuticals LLC

2006-09-21 Application granted granted Critical

2006-09-21 Publication of DE60030002D1 publication Critical patent/DE60030002D1/de

2007-03-08 Publication of DE60030002T2 publication Critical patent/DE60030002T2/de

2020-12-02 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Cardiology (AREA)
Biomedical Technology (AREA)
Pulmonology (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Dermatology (AREA)
Hematology (AREA)
Ophthalmology & Optometry (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Otolaryngology (AREA)
Immunology (AREA)
Obesity (AREA)
Psychology (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Reproductive Health (AREA)
Vascular Medicine (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

DE60030002T 1999-12-02 2000-12-01 Für den adenosin-a1-a2a-und-a3-rezeptor spezifische verbindungen und verwendungen davon Expired - Lifetime DE60030002T2 (de)

Applications Claiming Priority (7)

Application Number	Priority Date	Filing Date	Title
US45425499A	1999-12-02	1999-12-02
US09/454,074 US6878716B1 (en)	1998-06-02	1999-12-02	Compounds specific to adenosine A1 receptor and uses thereof
US454254		1999-12-02
US454075		1999-12-02
US09/454,075 US6686366B1 (en)	1998-06-02	1999-12-02	Compounds specific to adenosine A3 receptor and uses thereof
US454074		1999-12-02
PCT/US2000/032702 WO2001039777A1 (en)	1999-12-02	2000-12-01	Compounds specific to adenosine a1 a2a, and a3 receptors and uses thereof

Publications (2)

Publication Number	Publication Date
DE60030002D1 true DE60030002D1 (de)	2006-09-21
DE60030002T2 DE60030002T2 (de)	2007-03-08

Family

ID=27412585

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60030002T Expired - Lifetime DE60030002T2 (de)	1999-12-02	2000-12-01	Für den adenosin-a1-a2a-und-a3-rezeptor spezifische verbindungen und verwendungen davon

Country Status (15)

Country	Link
EP (2)	EP1246623B1 (de)
JP (1)	JP2003519102A (de)
KR (1)	KR100840727B1 (de)
AT (1)	ATE335489T1 (de)
AU (1)	AU784878B2 (de)
CA (1)	CA2393179A1 (de)
CY (1)	CY1107653T1 (de)
DE (1)	DE60030002T2 (de)
DK (1)	DK1246623T3 (de)
ES (1)	ES2269217T3 (de)
HK (1)	HK1050319B (de)
IL (2)	IL149935A0 (de)
MX (1)	MXPA02005357A (de)
PT (1)	PT1246623E (de)
WO (1)	WO2001039777A1 (de)

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US7473691B2 (en)	2000-09-15	2009-01-06	Vertex Pharmaceuticals Incorporated	Pyrazole compounds useful as protein kinase inhibitors
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CN1263757C (zh) *	2000-12-01	2006-07-12	Osi制药公司	特异于腺苷a1,a2a和a3受体的化合物及其应用
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UA80258C2 (en) *	2001-09-06	2007-09-10	Biogen Inc	Methods of treating pulmonary disease
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DK1450811T3 (da)	2001-11-30	2010-02-15	Osi Pharm Inc	Forbindelser specifikke af adenosin A1- og A3-receptorer og anvendelser heraf
EP1465634B1 (de)	2001-12-12	2014-10-22	The Government of the United States of America, as represented by the Secretary Department of Health and Human Services	Verfahren zur verwendung adenosinrezeptorinhibitoren zur verstärkung der immunantwort und entzündung
EA012926B1 (ru) *	2001-12-20	2010-02-26	Оси Фармасьютикалз, Инк.	Пирролопиримидиновые соединения, относящиеся к a-селективным антагонистам, их синтез и применение
JP4440642B2 (ja)	2001-12-20	2010-03-24	オーエスアイ・ファーマスーティカルズ・インコーポレーテッド	ピリミジンＡ２ｂ選択的アンタゴニスト化合物、それらの合成、及び使用
DE60236458D1 (de)	2001-12-20	2010-07-01	Osi Pharm Inc	Pyrrolopyrimidin a2b selektive antagonistische verbindungen, deren synthese und verwendung
IL163940A0 (en)	2002-03-13	2005-12-18	Euro Celtique Sa	Aryl substituted pyrimidines and the use thereof
MY141867A (en)	2002-06-20	2010-07-16	Vertex Pharma	Substituted pyrimidines useful as protein kinase inhibitors
JP4733388B2 (ja)	2002-08-02	2011-07-27	バーテックスファーマシューティカルズインコーポレイテッド	Ｇｓｋ−３のインヒビターとして有用なピラゾール組成物
JP4895806B2 (ja) *	2003-04-09	2012-03-14	エクセリクシス，インク．	Ｔｉｅ−２モジュレータと使用方法
AR043880A1 (es) *	2003-04-22	2005-08-17	Solvay Pharm Gmbh	Mesilato acido de 4-(4.trans-hidroxiciclohexil) amino-2-fenil-7h-pirrolo (2,3-d) pirimidina y sus formas polimorfas
WO2005004875A1 (ja) *	2003-07-14	2005-01-20	Sankyo Company, Limited	経肺投与用医薬組成物
BRPI0619708A2 (pt)	2005-11-03	2011-10-11	Vertex Pharma	composto, composição, método para inibir a atividade da proteìna aurora quinase numa amostra biológica, método para tratar distúrbio proliferativo e método para tratar cáncer
ATE504592T1 (de)	2006-03-27	2011-04-15	Otsuka Chemical Co Ltd	Trehaloseverbindung und arzneimittel mit der verbindung
EP2007373A4 (de) *	2006-03-29	2012-12-19	Foldrx Pharmaceuticals Inc	Hemmung der alpha-synuclein-toxizität
TW200808819A (en) *	2006-06-19	2008-02-16	Solvay Pharm Gmbh	Use of adenosine A1 antagonists in radiocontrast media induced nephrophaty
WO2008140051A1 (ja) *	2007-05-11	2008-11-20	Santen Pharmaceutical Co., Ltd.	非麦角系の選択的ｄ２受容体アゴニストを有効成分として含有する後眼部疾患の予防又は治療剤
WO2009052376A1 (en)	2007-10-18	2009-04-23	Musc Foundation For Research Development	Methods for the diagnosis of genitourinary cancer
AR070127A1 (es)	2008-01-11	2010-03-17	Novartis Ag	Pirrolo - pirimidinas y pirrolo -piridinas
ES2617339T3 (es) *	2010-12-16	2017-06-16	Calchan Limited	Derivados de pirrolopirimidina inhibidores de ASK1
CA2873723A1 (en) *	2012-06-07	2013-12-12	F. Hoffmann-La Roche Ag	Pyrrolopyrimidone and pyrrolopyridone inhibitors of tankyrase
GB201711234D0 (en)	2017-07-12	2017-08-23	Galapagos Nv	Pyrrolopyrimidine and pyrrolopyridine derivatives
KR20240018000A (ko) *	2022-08-01	2024-02-13	주식회사 넥스트젠바이오사이언스	A3 아데노신 수용체 작용제로서의 신규한 퓨린 유도체 화합물
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2000
- 2000-12-01 KR KR1020027007039A patent/KR100840727B1/ko not_active Expired - Fee Related
- 2000-12-01 AT AT00988011T patent/ATE335489T1/de active
- 2000-12-01 CA CA002393179A patent/CA2393179A1/en not_active Abandoned
- 2000-12-01 EP EP00988011A patent/EP1246623B1/de not_active Expired - Lifetime
- 2000-12-01 WO PCT/US2000/032702 patent/WO2001039777A1/en active Application Filing
- 2000-12-01 AU AU24270/01A patent/AU784878B2/en not_active Ceased
- 2000-12-01 EP EP06016543A patent/EP1731520A1/de not_active Withdrawn
- 2000-12-01 PT PT00988011T patent/PT1246623E/pt unknown
- 2000-12-01 ES ES00988011T patent/ES2269217T3/es not_active Expired - Lifetime
- 2000-12-01 IL IL14993500A patent/IL149935A0/xx unknown
- 2000-12-01 JP JP2001541509A patent/JP2003519102A/ja active Pending
- 2000-12-01 DE DE60030002T patent/DE60030002T2/de not_active Expired - Lifetime
- 2000-12-01 DK DK00988011T patent/DK1246623T3/da active
- 2000-12-01 MX MXPA02005357A patent/MXPA02005357A/es active IP Right Grant
2003
- 2003-03-28 HK HK03102257.1A patent/HK1050319B/zh not_active IP Right Cessation
2006
- 2006-09-04 CY CY20061101246T patent/CY1107653T1/el unknown
2009
- 2009-07-15 IL IL199869A patent/IL199869A0/en unknown

Also Published As

Publication number	Publication date
EP1246623A4 (de)	2003-05-14
IL199869A0 (en)	2011-08-01
WO2001039777A1 (en)	2001-06-07
WO2001039777A8 (en)	2001-11-08
CA2393179A1 (en)	2001-06-07
HK1050319A1 (en)	2003-06-20
EP1246623A1 (de)	2002-10-09
JP2003519102A (ja)	2003-06-17
PT1246623E (pt)	2006-12-29
CY1107653T1 (el)	2013-04-18
AU2427001A (en)	2001-06-12
EP1731520A1 (de)	2006-12-13
ATE335489T1 (de)	2006-09-15
IL149935A0 (en)	2002-11-10
MXPA02005357A (es)	2003-05-19
HK1050319B (zh)	2007-04-04
DE60030002T2 (de)	2007-03-08
KR20020064327A (ko)	2002-08-07
ES2269217T3 (es)	2007-04-01
KR100840727B1 (ko)	2008-06-23
EP1246623B1 (de)	2006-08-09
DK1246623T3 (da)	2006-11-13
AU784878B2 (en)	2006-07-13

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AP1893A (en)	2008-09-23	Compounds specific to adenosine A1, A2A and A3 receptor and uses thereof
EP1450811A4 (de)	2005-11-16	2-ARYLPYRROLOPYRIMIDINE FÜR ADENOSIN A sb 1 /sb UND A sb 3 /sb REZEPTOREN
CY1113610T1 (el)	2016-06-22	Συνθεσεις και μεθοδοι για αγωγη μιτοχονδριακων παθησεων
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PL335140A1 (en)	2000-04-10	Therapeutic agent for treating lymphatic system carcinomas
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BR0009524A (pt)	2002-02-19	Uso de um composto, e, composição farmacêutica ou veterinaria
BG104357A (en)	2000-12-29	Derivatives of cyclopentene used as motiline receptor antagonists
ES2082587T3 (es)	1996-03-16	El uso de l-deprenyl para la fabricacion de un medicamento para el tratamiento de la enfermedad de cushing.
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ITTO920096A0 (it)	1992-02-07	Scocca polivalente per un veicolo
BR9406034A (pt)	1996-01-02	Derivados de imidazoloquinoxalinonas como antagonistas de eaa.
ITMI920591A1 (it)	1993-09-13	Composizioni farmaceutiche comprendenti monosialoganglioside gm1 o un suo derivato atte al trattamento della malattia di parkinson
DE69009765D1 (de)	1994-07-14	Kynurensäurederivate, deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
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Date	Code	Title	Description
2007-08-30	8364	No opposition during term of opposition