ATE197051T1 - Pharmazeutisch wirksame bicyclisch heterocyclische amine - Google Patents
Pharmazeutisch wirksame bicyclisch heterocyclische amineInfo
- Publication number
- ATE197051T1 ATE197051T1 AT93908303T AT93908303T ATE197051T1 AT E197051 T1 ATE197051 T1 AT E197051T1 AT 93908303 T AT93908303 T AT 93908303T AT 93908303 T AT93908303 T AT 93908303T AT E197051 T1 ATE197051 T1 AT E197051T1
- Authority
- AT
- Austria
- Prior art keywords
- pharmaceutically active
- bicyclic heterocyclic
- heterocyclic amine
- active bicyclic
- xxx
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Hospice & Palliative Care (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86364692A | 1992-04-03 | 1992-04-03 | |
PCT/US1993/002188 WO1993020078A1 (en) | 1992-04-03 | 1993-03-16 | Pharmaceutically active bicyclic-heterocyclic amines |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE197051T1 true ATE197051T1 (de) | 2000-11-15 |
Family
ID=25341481
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT93908303T ATE197051T1 (de) | 1992-04-03 | 1993-03-16 | Pharmazeutisch wirksame bicyclisch heterocyclische amine |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP0633886B1 (de) |
JP (1) | JPH08502721A (de) |
KR (1) | KR100284473B1 (de) |
AT (1) | ATE197051T1 (de) |
AU (1) | AU675932B2 (de) |
CA (1) | CA2130937A1 (de) |
CZ (1) | CZ236494A3 (de) |
DE (1) | DE69329574T2 (de) |
DK (1) | DK0633886T3 (de) |
ES (1) | ES2150941T3 (de) |
FI (1) | FI944602A0 (de) |
GR (1) | GR3035188T3 (de) |
HU (1) | HUT70954A (de) |
LV (1) | LV12794B (de) |
MX (1) | MX9301847A (de) |
NO (1) | NO303542B1 (de) |
PL (2) | PL175327B1 (de) |
PT (1) | PT633886E (de) |
RU (1) | RU2103272C1 (de) |
SK (1) | SK119194A3 (de) |
WO (1) | WO1993020078A1 (de) |
Families Citing this family (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0812322A1 (de) * | 1995-03-02 | 1997-12-17 | PHARMACIA & UPJOHN COMPANY | Pyrimido(4,5-b)indole |
WO1998022457A1 (en) | 1996-11-19 | 1998-05-28 | Amgen Inc. | Aryl and heteroaryl substituted fused pyrrole antiinflammatory agents |
WO1998024453A1 (fr) * | 1996-12-05 | 1998-06-11 | Nippon Shinyaku Co., Ltd. | Medicaments pour la myelopathie |
WO1998042708A2 (en) * | 1997-01-08 | 1998-10-01 | Pharmacia & Upjohn Company | Pharmaceutically active tricyclic amines |
GB9716657D0 (en) | 1997-08-07 | 1997-10-15 | Zeneca Ltd | Chemical compounds |
GB2331988B (en) * | 1997-12-04 | 2003-04-16 | Imperial College | Polycyclic sulphamate inhibitors or oestrone sulphatase |
GB9803226D0 (en) | 1998-02-17 | 1998-04-08 | Zeneca Ltd | Chemical compounds |
US6686366B1 (en) | 1998-06-02 | 2004-02-03 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A3 receptor and uses thereof |
NZ508314A (en) * | 1998-06-02 | 2004-03-26 | Osi Pharm Inc | Pyrrolo[2,3d]pyrimidine compositions and their use |
US6878716B1 (en) | 1998-06-02 | 2005-04-12 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A1 receptor and uses thereof |
PA8474101A1 (es) * | 1998-06-19 | 2000-09-29 | Pfizer Prod Inc | Compuestos de pirrolo [2,3-d] pirimidina |
JP2003524598A (ja) * | 1998-09-04 | 2003-08-19 | アルタナ ファルマ アクチエンゲゼルシャフト | 新規ピラノセン |
GB9902452D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
GB9902455D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
GB9902453D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
GB9902461D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
GB9902459D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
GB9918035D0 (en) | 1999-07-30 | 1999-09-29 | Novartis Ag | Organic compounds |
US6664252B2 (en) | 1999-12-02 | 2003-12-16 | Osi Pharmaceuticals, Inc. | 4-aminopyrrolo[2,3-d]pyrimidine compounds specific to adenosine A2a receptor and uses thereof |
JP2003519102A (ja) | 1999-12-02 | 2003-06-17 | オーエスアイ・ファーマスーティカルズ・インコーポレーテッド | アデノシンa▲下1▼、a▲下2a▼およびa▲下3▼受容体に対して特異的な化合物並びにその使用 |
US6680322B2 (en) | 1999-12-02 | 2004-01-20 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A1 receptors and uses thereof |
US7160890B2 (en) | 1999-12-02 | 2007-01-09 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A3 receptor and uses thereof |
CA2395520A1 (en) | 1999-12-21 | 2001-06-28 | Sugen, Inc. | 4-substituted 7-aza-indolin-2-ones and their use as protein kinase inhibitors |
GB0000625D0 (en) | 2000-01-13 | 2000-03-01 | Zeneca Ltd | Chemical compounds |
EP1254115A2 (de) | 2000-02-11 | 2002-11-06 | Bristol-Myers Squibb Company | Cannabinoid-rezeptor modulatoren, verfahren zu ihrer herstellung, und verwendung der cannabinoid-rezeptor modulatoren um respiratorische und nicht respiratorische krankheiten zu behandeln |
US20020061897A1 (en) | 2000-03-30 | 2002-05-23 | Elliott Richard L. | Neuropeptide Y antagonists |
DE60128475T2 (de) | 2000-07-25 | 2008-02-07 | Merck & Co., Inc. | N-substituierte indole mit anwendung in der behandlung von diabetes |
SE0003795D0 (sv) | 2000-10-20 | 2000-10-20 | Astrazeneca Ab | Pharmaceutically useful compounds |
US6680324B2 (en) | 2000-12-01 | 2004-01-20 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A1 receptors and uses thereof |
US6673802B2 (en) | 2000-12-01 | 2004-01-06 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A3 receptor and uses thereof |
GB0100622D0 (en) | 2001-01-10 | 2001-02-21 | Vernalis Res Ltd | Chemical compounds V111 |
GB0117396D0 (en) | 2001-07-17 | 2001-09-05 | Glaxo Group Ltd | Chemical compounds |
DK1450811T3 (da) | 2001-11-30 | 2010-02-15 | Osi Pharm Inc | Forbindelser specifikke af adenosin A1- og A3-receptorer og anvendelser heraf |
US20030229067A1 (en) | 2001-12-20 | 2003-12-11 | Arlindo Castelhano | Pyrrolopyrimidine A2b selective antagonist compounds, their synthesis and use |
KR20040068317A (ko) | 2001-12-20 | 2004-07-30 | 오에스아이 파마슈티컬스, 인코포레이티드 | 피리미딘 a₂b 선택성 길항 화합물, 그의 합성 방법 및용도 |
WO2004092170A2 (en) | 2003-04-09 | 2004-10-28 | Biogen Idec Ma Inc. | Triazolotriazines and pyrazolotriazines useful as a2a adenosine receptor antagon ists |
US7674791B2 (en) | 2003-04-09 | 2010-03-09 | Biogen Idec Ma Inc. | Triazolopyrazines and methods of making and using the same |
ATE418555T1 (de) | 2003-04-09 | 2009-01-15 | Biogen Idec Inc | A2a-adenosinrezeptorantagonisten |
GB0308208D0 (en) | 2003-04-09 | 2003-05-14 | Glaxo Group Ltd | Chemical compounds |
EP1704135A4 (de) * | 2003-12-23 | 2007-10-24 | Abraxis Bioscience Inc | Propofolanaloga, verfahren zu deren herstellung und anwendungsverfahren |
RU2387663C2 (ru) | 2004-03-04 | 2010-04-27 | Киссеи Фармасьютикал Ко., Лтд. | Конденсированные гетероциклические производные, содержащие их медицинские композиции и их медицинское применение |
US7696210B2 (en) | 2004-06-17 | 2010-04-13 | Wyeth | Gonadotropin releasing hormone receptor antagonists |
WO2006009736A1 (en) | 2004-06-17 | 2006-01-26 | Wyeth | Processes for preparing gonadotropin releasing hormone receptor antagonists |
AU2005254782A1 (en) | 2004-06-18 | 2005-12-29 | Biolipox Ab | Indoles useful in the treatment of inflammation |
FR2880626B1 (fr) * | 2005-01-13 | 2008-04-18 | Aventis Pharma Sa | Derives de la purine, compositions les contenant et utilisation |
CA2593155A1 (en) | 2005-01-19 | 2006-07-27 | Biolipox Ab | Indoles useful in the treatment of inflammation |
US7534796B2 (en) | 2005-02-18 | 2009-05-19 | Wyeth | Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor |
US7582634B2 (en) | 2005-02-18 | 2009-09-01 | Wyeth | 7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor |
US7538113B2 (en) | 2005-02-18 | 2009-05-26 | Wyeth | 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor |
FR2884824B1 (fr) | 2005-04-20 | 2007-07-13 | Sanofi Aventis Sa | Derives de 1h-pyrimido[4,5-b]indole, leur preparation et leur application en therapeutique |
US7531542B2 (en) | 2005-05-18 | 2009-05-12 | Wyeth | Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor |
US7582636B2 (en) | 2005-05-26 | 2009-09-01 | Wyeth | Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of Gonadotropin Releasing Hormone receptor |
UA95788C2 (en) | 2005-12-15 | 2011-09-12 | Ф. Хоффманн-Ля Рош Аг | Fused pyrrole derivatives |
KR100749216B1 (ko) * | 2006-08-30 | 2007-08-13 | 위아 주식회사 | 4륜구동차량용 부변속기 |
WO2008055808A1 (en) | 2006-11-09 | 2008-05-15 | F. Hoffmann-La Roche Ag | Indole and benzofuran 2-carboxamide derivatives |
BRPI0814777A2 (pt) * | 2007-08-08 | 2015-03-03 | Glaxosmithkline Llc | Composto, composição farmacêutica, método para tratar um neoplasma, uso de um composto, e, composição farmacêutica. |
US8436038B2 (en) * | 2007-08-17 | 2013-05-07 | Lg Life Sciences Ltd. | Indole and indazole compounds as an inhibitor of cellular necrosis |
AR070127A1 (es) | 2008-01-11 | 2010-03-17 | Novartis Ag | Pirrolo - pirimidinas y pirrolo -piridinas |
AU2009210296B2 (en) | 2008-01-31 | 2013-11-14 | Sanofi | Cyclic azaindole-3-carboxamides, their preparation and their use as pharmaceuticals |
TW200938201A (en) * | 2008-02-07 | 2009-09-16 | Chugai Pharmaceutical Co Ltd | Pyrrolopyrimidine derivative as PI3K inhibitor and use thereof |
KR20110098908A (ko) * | 2008-11-11 | 2011-09-02 | 엑스커버리 홀딩 컴퍼니 엘엘씨 | PI3K/mTOR 키나제 억제제 |
ES2616238T3 (es) | 2010-10-06 | 2017-06-12 | Glaxosmithkline Llc, Corporation Service Company | Derivados de bencimidazol como inhibidores de PI3 quinasa |
ES2611885T3 (es) | 2011-01-31 | 2017-05-11 | Novartis Ag | Derivados heterocíclicos novedosos |
AU2012229997B2 (en) | 2011-03-15 | 2016-04-14 | Lawrence Livermore National Security, Llc | Tricyclic gyrase inhibitors |
CA2853256C (en) | 2011-10-28 | 2019-05-14 | Novartis Ag | Novel purine derivatives and their use in the treatment of disease |
SG11201404241SA (en) | 2012-01-27 | 2014-08-28 | Univ Montreal | Pyrimido[4,5-b]indole derivatives and use thereof in the expansion of hematopoietic stem cells |
BR112014032913A2 (pt) | 2012-06-29 | 2017-06-27 | Pfizer | novas 4-(amino-substituídas)-7h-pirrolo[2,3-d]pirimidinas como inibidores de lrrk2 |
EP3083618B1 (de) | 2013-12-17 | 2018-02-21 | Pfizer Inc | Neuartige 3,4-disubstituierte-1h-pyrrolo[2,3-b]pyridine und 4,5-disubstituierte 7h-pyrrolo[2,3-c]pyridazine als lrrk2-hemmer |
JP2017510628A (ja) | 2014-03-13 | 2017-04-13 | エージェンシー フォー サイエンス,テクノロジー アンド リサーチ | 縮合ピリミジン系ヒドロキサメート誘導体 |
WO2016048861A2 (en) * | 2014-09-22 | 2016-03-31 | National Health Research Institutes | Heterocyclic compounds and use thereof |
AU2016273439B2 (en) | 2015-06-05 | 2020-11-05 | Héma-Québec | Methods for culturing and/or differentiating hematopoietic stem cells into progenitors and uses thereof |
WO2017046675A1 (en) | 2015-09-14 | 2017-03-23 | Pfizer Inc. | Novel imidazo [4,5-c] quinoline and imidazo [4,5-c][1,5] naphthyridine derivatives as lrrk2 inhibitors |
US9630968B1 (en) | 2015-12-23 | 2017-04-25 | Arqule, Inc. | Tetrahydropyranyl amino-pyrrolopyrimidinone and methods of use thereof |
MX2019002212A (es) | 2016-08-24 | 2019-07-08 | Arqule Inc | Compuestos de amino-pirrolo-pirimidinona y metodos de uso de los mismos. |
TW201813963A (zh) | 2016-09-23 | 2018-04-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
TW201825465A (zh) | 2016-09-23 | 2018-07-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
TW201815787A (zh) | 2016-09-23 | 2018-05-01 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
US20200399268A1 (en) * | 2018-02-16 | 2020-12-24 | UCB Biopharma SRL | Pharmaceutical 6,5 Heterobicyclic Ring Derivatives |
MX2021007925A (es) * | 2018-12-31 | 2021-10-26 | Biomea Fusion Llc | Inhibidores irreversibles de la interaccion menina-mll. |
US20240150358A1 (en) * | 2020-06-03 | 2024-05-09 | Kineta, Inc. | Purines and methods of their use |
WO2021263079A1 (en) * | 2020-06-26 | 2021-12-30 | Tempest Therapeutics, Inc. | Trex1 inhibitors and uses thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB864145A (en) * | 1959-06-02 | 1961-03-29 | Thomae Gmbh Dr K | Novel purines and a process for their manufacture |
GB1268772A (en) * | 1968-03-15 | 1972-03-29 | Glaxo Lab Ltd | NOVEL alpha-CARBOLINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME |
DE69027862T2 (de) * | 1989-09-19 | 1997-03-06 | Teijin Ltd., Osaka | Pyrrolo[2,3-d]pyrimidinderivate, verfahren zur herstellung und arzneimittelzusammensetzungen die diese enthalten |
-
1993
- 1993-03-16 CA CA002130937A patent/CA2130937A1/en not_active Abandoned
- 1993-03-16 PL PL93317810A patent/PL175327B1/pl not_active IP Right Cessation
- 1993-03-16 PT PT93908303T patent/PT633886E/pt unknown
- 1993-03-16 DK DK93908303T patent/DK0633886T3/da active
- 1993-03-16 PL PL93305430A patent/PL175347B1/pl not_active IP Right Cessation
- 1993-03-16 WO PCT/US1993/002188 patent/WO1993020078A1/en not_active Application Discontinuation
- 1993-03-16 HU HU9402829A patent/HUT70954A/hu unknown
- 1993-03-16 SK SK1191-94A patent/SK119194A3/sk unknown
- 1993-03-16 CZ CZ942364A patent/CZ236494A3/cs unknown
- 1993-03-16 JP JP5517457A patent/JPH08502721A/ja active Pending
- 1993-03-16 KR KR1019940703452A patent/KR100284473B1/ko not_active Expired - Fee Related
- 1993-03-16 AT AT93908303T patent/ATE197051T1/de not_active IP Right Cessation
- 1993-03-16 RU RU94042466A patent/RU2103272C1/ru not_active IP Right Cessation
- 1993-03-16 ES ES93908303T patent/ES2150941T3/es not_active Expired - Lifetime
- 1993-03-16 EP EP93908303A patent/EP0633886B1/de not_active Expired - Lifetime
- 1993-03-16 AU AU39174/93A patent/AU675932B2/en not_active Ceased
- 1993-03-16 DE DE69329574T patent/DE69329574T2/de not_active Expired - Fee Related
- 1993-03-31 MX MX9301847A patent/MX9301847A/es not_active IP Right Cessation
-
1994
- 1994-09-30 NO NO943655A patent/NO303542B1/no unknown
- 1994-10-03 FI FI944602A patent/FI944602A0/fi not_active Application Discontinuation
-
2001
- 2001-01-04 GR GR20010400006T patent/GR3035188T3/el not_active IP Right Cessation
- 2001-10-18 LV LVP-01-150A patent/LV12794B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
LV12794B (lv) | 2002-06-20 |
EP0633886B1 (de) | 2000-10-18 |
SK119194A3 (en) | 1995-05-10 |
FI944602L (fi) | 1994-10-03 |
KR100284473B1 (ko) | 2001-04-02 |
NO303542B1 (no) | 1998-07-27 |
FI944602A0 (fi) | 1994-10-03 |
PL175347B1 (pl) | 1998-12-31 |
DE69329574T2 (de) | 2001-05-31 |
HUT70954A (en) | 1995-11-28 |
CZ236494A3 (en) | 1994-12-15 |
MX9301847A (es) | 1993-10-01 |
NO943655D0 (no) | 1994-09-30 |
DE69329574D1 (de) | 2000-11-23 |
KR950700912A (ko) | 1995-02-20 |
RU2103272C1 (ru) | 1998-01-27 |
PT633886E (pt) | 2001-03-30 |
EP0633886A1 (de) | 1995-01-18 |
JPH08502721A (ja) | 1996-03-26 |
WO1993020078A1 (en) | 1993-10-14 |
AU675932B2 (en) | 1997-02-27 |
CA2130937A1 (en) | 1993-10-14 |
AU3917493A (en) | 1993-11-08 |
HU9402829D0 (en) | 1995-02-28 |
GR3035188T3 (en) | 2001-04-30 |
DK0633886T3 (da) | 2000-12-18 |
RU94042466A (ru) | 1996-07-20 |
ES2150941T3 (es) | 2000-12-16 |
PL175327B1 (pl) | 1998-12-31 |
LV12794A (en) | 2002-02-20 |
NO943655L (no) | 1994-12-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE197051T1 (de) | Pharmazeutisch wirksame bicyclisch heterocyclische amine | |
BR0112756A (pt) | Composto, composição farmacêutica, métodos para o tratamento de doenças mediadas por prostaglandina, de congestão nasal, asma alérgica, e rinite alérgica, e, uso de um composto | |
IS6560A (is) | Lyfjasamsetning fyrir meðhöndlun á bráðum, þrálátum sársauka og/eða taugakerfissársauka og mígreni | |
LU92166I2 (fr) | Glycopyrronium ou un de ses sels | |
ATE415974T1 (de) | Immunmodulatorische verbindungen sowie deren verwendungsverfahren | |
NO20025450D0 (no) | Ny farmasöytisk sammensetning | |
IL144294A0 (en) | P53 inhibitors and therapeutic use of the same | |
BG101118A (en) | Therapeutical compounds | |
TR199900204T2 (xx) | Fluor i�eren 1,4-diikameli piperidin t�revleri. | |
EA200200306A1 (ru) | Трициклические ингибиторы поли(адф-рибозо)полимераз | |
BR9917038A (pt) | Composto, composição farmacêutica, método de modulação da atividade receptora de quimocinas, método de tratamento ou prevenção de doenças inflamatórias, método de tratamento ou prevenção de asma e método de tratamento ou prevenção de disfunções inflamatórias | |
WO2002002506A3 (en) | Compounds to treat alzheimer's disease | |
BR9807673A (pt) | Processos para tratar asma alérgica e dermatite em um humano e composição farmacêutica. | |
NO20030724L (no) | Anvendelse av derivater av valproinsyreamider og 2- valproensyreamider for terapi eller prevensjon av smerte- og/eller hodepinelidelser | |
BR9903737A (pt) | Carbamatos em c-11 de macrólidos antibacterianos | |
SE9900833D0 (sv) | Novel combination | |
CA2427814A1 (en) | A combination of a pde4 inhibitor and a leukotriene antagonist in the treatment of bronchial and respiratory disorders | |
UA42719C2 (uk) | Сполуки, композиції та способи, які інгібують протеази, для лікування та профілактики імуномедіаторних запальних хвороб | |
ES2184300T3 (es) | Derivados de aminoacidos utiles para tratar el accidente vascular encefalico. | |
SE9900834D0 (sv) | Novel combination | |
DE69103773D1 (de) | Derivate von hydroxaminsäure die lipoxygenase hemmen. | |
MY130725A (en) | Composition and method for treating allergic diseases | |
PT882038E (pt) | N-metil-n-(4-(piperidin-1-il)-2-(aril)butil)benzamidas substituidas vantajosas para o tratamento de doencas alergicas | |
SE8402199D0 (sv) | Pharmazeutisches preparat enthaltend co-dergocrine und einen calcium-antagonisten | |
DE69731620D1 (de) | Neue substituierte n-methyl-n-(4-(4-(1h-benzimidazol-2-yl) (1,4)diazepan-1-yl)-2-(aryl)butyl)benzamide zur behandlung von allergischen krankheiten |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |