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DE60005300D1 - 2,3-o-isoproylidene derivativen von monosacchariden und verwendung als zell-adhäsion-inhibitoren - Google Patents

2,3-o-isoproylidene derivativen von monosacchariden und verwendung als zell-adhäsion-inhibitoren

Info

Publication number
DE60005300D1
DE60005300D1 DE60005300T DE60005300T DE60005300D1 DE 60005300 D1 DE60005300 D1 DE 60005300D1 DE 60005300 T DE60005300 T DE 60005300T DE 60005300 T DE60005300 T DE 60005300T DE 60005300 D1 DE60005300 D1 DE 60005300D1
Authority
DE
Germany
Prior art keywords
isoproylidene
monosaccharides
derivatives
cell adhesion
adhesion inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60005300T
Other languages
English (en)
Other versions
DE60005300T2 (de
Inventor
Sudershan K Arora
Nawal Kishore
Jang Bahadur Gupta
Vishwas D Joshi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ranbaxy Laboratories Ltd
Original Assignee
Ranbaxy Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Publication of DE60005300D1 publication Critical patent/DE60005300D1/de
Application granted granted Critical
Publication of DE60005300T2 publication Critical patent/DE60005300T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04Cyclic acetals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE60005300T 1999-01-15 2000-01-10 2,3-o-isoproylidene derivativen von monosacchariden und verwendung als zell-adhäsion-inhibitoren Expired - Fee Related DE60005300T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN86DE1999 IN190975B (de) 1999-01-15 1999-01-15
INDE008699 1999-01-15
US276368 1999-03-25
US09/276,368 US6590085B1 (en) 1999-01-15 1999-03-25 Derivatives of monosaccharides as cell adhesion inhibitors
PCT/IB2000/000022 WO2000042054A1 (en) 1999-01-15 2000-01-10 2,3-o-isopropylidene derivatives of monosaccharides as cell adhesion inhibitors

Publications (2)

Publication Number Publication Date
DE60005300D1 true DE60005300D1 (de) 2003-10-23
DE60005300T2 DE60005300T2 (de) 2004-07-15

Family

ID=11088155

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60005300T Expired - Fee Related DE60005300T2 (de) 1999-01-15 2000-01-10 2,3-o-isoproylidene derivativen von monosacchariden und verwendung als zell-adhäsion-inhibitoren

Country Status (31)

Country Link
US (5) US6590085B1 (de)
EP (1) EP1147119B1 (de)
JP (1) JP2002534530A (de)
CN (1) CN1167707C (de)
AR (1) AR022235A1 (de)
AT (1) ATE250074T1 (de)
AU (1) AU768511B2 (de)
BG (1) BG105745A (de)
BR (1) BR0007553A (de)
CA (1) CA2359986A1 (de)
CO (1) CO5180591A1 (de)
CR (1) CR6423A (de)
CZ (1) CZ20012540A3 (de)
DE (1) DE60005300T2 (de)
DK (1) DK1147119T3 (de)
ES (1) ES2206176T3 (de)
HK (1) HK1041270A1 (de)
HR (1) HRP20010529B1 (de)
HU (1) HUP0105116A3 (de)
ID (1) ID30351A (de)
IN (1) IN190975B (de)
MA (1) MA25342A1 (de)
MX (1) MXPA01007187A (de)
MY (1) MY121135A (de)
NZ (2) NZ512852A (de)
PA (1) PA8489901A1 (de)
PT (1) PT1147119E (de)
SK (1) SK284241B6 (de)
TR (1) TR200102043T2 (de)
WO (1) WO2000042054A1 (de)
YU (1) YU50701A (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN190975B (de) * 1999-01-15 2003-09-06 Ranbaxy Lab Ltd
WO2004106299A2 (en) 2003-05-30 2004-12-09 Ranbaxy Laboratories Limited Substituted pyrrole derivatives and their use as hmg-co inhibitors
EP1789428A1 (de) * 2004-09-02 2007-05-30 Ranbaxy Laboratories Limited Monosaccharidderivate
WO2007063356A2 (en) * 2004-12-22 2007-06-07 Ranbaxy Laboratories Limited Derivatives of pentose monosaccharides as anti-inflammatory compounds
EP1915160A2 (de) * 2005-07-22 2008-04-30 Ranbaxy Laboratories Limited Derivate von monosacchariden zur behandlung von copd und der allergischen rhinitis
CA2627599A1 (en) * 2005-11-08 2007-05-18 Ranbaxy Laboratories Limited Process for (3r,5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxy methyl phenyl amino)carbonyl]-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid hemi calcium salt
CL2007000667A1 (es) * 2006-03-14 2008-03-14 Ranbaxi Lab Ltd Composicion farmaceutica que comprende al acido 7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroximetilfenilamino)carbonil]pirrol-1-il]-3,5-dihidroxi-heptanoico o una sal y al menos un agente estabilizante; procedimiento de preparacion, util en e
EP1842855A3 (de) * 2006-03-29 2007-12-05 Ranbaxy Laboratories Limited Monosaccharidderivate als Entzündungshemmende und/oder Anti-Tumor Agentien
EP1864992A2 (de) * 2006-05-30 2007-12-12 Ranbaxy Laboratories, Ltd. Monosaccharidderivate
US20080300196A1 (en) * 2006-10-03 2008-12-04 Ashwani Kumar Verma Monosaccharide derivatives
US10034995B2 (en) * 2007-09-20 2018-07-31 Resmed Limited Retractable tube for CPAP

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2715121A (en) 1950-09-09 1955-08-09 American Home Prod Alkyl sugar derivatives and their preparation
US4056322A (en) 1973-12-14 1977-11-01 Strategic Medical Research Corporation Preparation of ethers of monosaccharides
US4735934A (en) 1981-02-17 1988-04-05 Greenwich Pharmaceuticals Incorporated Method of therapeutically treating a warm blooded animal afflicted with an autoimmune disease
US4996195A (en) 1989-01-09 1991-02-26 Greenwich Pharmaceuticals Inc. Derivatives of α,D-glucofuranose or α,D-allofuranose and intermediates for preparing these derivatives
US5010058A (en) * 1989-06-22 1991-04-23 501 Greenwich Pharmaceuticals Incorporated 3,5,6-substituted derivatives of 1,2-O-isopropylidene-α,D-glucofuranose and intermediates for preparing these derivatives
FR2652540B1 (fr) 1989-10-02 1995-06-02 Imaje Sa Circuit d'encre notamment destine a la mise en pression d'une encre a pigments pour imprimante a jet d'encre.
US5192746A (en) 1990-07-09 1993-03-09 Tanabe Seiyaku Co., Ltd. Cyclic cell adhesion modulation compounds
US5258402A (en) 1992-06-11 1993-11-02 Mcneil-Ppc, Inc. Imidate derivatives of pharmaceutically useful anticonvulsant sulfamates
US5432163A (en) 1992-11-13 1995-07-11 Greenwich Pharmaceuticals Incorporated Anti-proliferative and anti-inflammatory compounds: derivatives of pentose monosaccharides
US5637570A (en) * 1995-05-09 1997-06-10 Chemora Pharmochem Disubstituted and trisubstituted derivatives of 2,3:4,6-di-O-isopropylidene-α-L-xylo-2-hexulofuranosonic acid having anti-cancer, anti-inflammatory and anti-proliferative activity
IN190975B (de) * 1999-01-15 2003-09-06 Ranbaxy Lab Ltd

Also Published As

Publication number Publication date
MY121135A (en) 2005-12-30
BR0007553A (pt) 2001-12-18
ES2206176T3 (es) 2004-05-16
CN1343213A (zh) 2002-04-03
PA8489901A1 (es) 2000-09-29
US7037899B2 (en) 2006-05-02
AU768511B2 (en) 2003-12-18
EP1147119A1 (de) 2001-10-24
NZ512852A (en) 2004-02-27
CN1167707C (zh) 2004-09-22
HRP20010529A2 (en) 2002-08-31
IN190975B (de) 2003-09-06
SK284241B6 (en) 2004-11-03
US20040019191A1 (en) 2004-01-29
CO5180591A1 (es) 2002-07-30
WO2000042054A1 (en) 2000-07-20
MA25342A1 (fr) 2001-12-31
MXPA01007187A (es) 2002-04-24
US6590085B1 (en) 2003-07-08
DE60005300T2 (de) 2004-07-15
AU1886100A (en) 2000-08-01
ID30351A (id) 2001-11-22
ATE250074T1 (de) 2003-10-15
US20040018995A1 (en) 2004-01-29
HUP0105116A2 (hu) 2003-04-28
HUP0105116A3 (en) 2003-05-28
US7005516B2 (en) 2006-02-28
HK1041270A1 (en) 2002-07-05
AR022235A1 (es) 2002-09-04
US7005422B2 (en) 2006-02-28
CR6423A (de) 2004-03-09
NZ527483A (en) 2005-02-25
BG105745A (en) 2002-05-31
US20040029820A1 (en) 2004-02-12
DK1147119T3 (da) 2004-01-19
JP2002534530A (ja) 2002-10-15
SK10132001A3 (sk) 2002-01-07
TR200102043T2 (tr) 2001-11-21
CZ20012540A3 (cs) 2002-02-13
CA2359986A1 (en) 2000-07-20
HRP20010529B1 (en) 2005-02-28
US20040023900A1 (en) 2004-02-05
EP1147119B1 (de) 2003-09-17
YU50701A (sh) 2005-06-10
PT1147119E (pt) 2004-02-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee