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CY1119912T1 - Αντιγονα και συνδυασμοι αντιγονων pseudomonas - Google Patents

Αντιγονα και συνδυασμοι αντιγονων pseudomonas

Info

Publication number
CY1119912T1
CY1119912T1 CY20181100174T CY181100174T CY1119912T1 CY 1119912 T1 CY1119912 T1 CY 1119912T1 CY 20181100174 T CY20181100174 T CY 20181100174T CY 181100174 T CY181100174 T CY 181100174T CY 1119912 T1 CY1119912 T1 CY 1119912T1
Authority
CY
Cyprus
Prior art keywords
antigon
combinations
antigens
pseudomonas antigens
pseudomonas aeruginosa
Prior art date
Application number
CY20181100174T
Other languages
English (en)
Inventor
Vega Masignani
Maria Scarselli
Roberto Petracca
Irene BIANCONI
Alessandra BRAGONZI
Beatriz ALCALA' FRANCO
Original Assignee
Glaxosmithkline Biologicals S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals S.A. filed Critical Glaxosmithkline Biologicals S.A.
Publication of CY1119912T1 publication Critical patent/CY1119912T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/104Pseudomonadales, e.g. Pseudomonas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6087Polysaccharides; Lipopolysaccharides [LPS]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Ένα αποτελεσματικό εμβόλιο Pseudomonas aeruginosa μπορεί να απαιτεί ένα ή περισσότερα αντιγονικά συστατικά, και έτσι ταυτοποιούνται ποικίλα αντιγόνα Pseudomonas aeruginosa για χρήση σε ανοσοποίηση. Τα εν λόγω πολυπεπτίδια μπορεί προαιρετικώς να χρησιμοποιηθούν σε συνδυασμό με άλλα νοσοκομειακά αντιγόνα.
CY20181100174T 2012-11-30 2018-02-13 Αντιγονα και συνδυασμοι αντιγονων pseudomonas CY1119912T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB201221638 2012-11-30
PCT/EP2013/074864 WO2014083060A2 (en) 2012-11-30 2013-11-27 Pseudomonas antigens and antigen combinations

Publications (1)

Publication Number Publication Date
CY1119912T1 true CY1119912T1 (el) 2018-06-27

Family

ID=49681020

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20181100174T CY1119912T1 (el) 2012-11-30 2018-02-13 Αντιγονα και συνδυασμοι αντιγονων pseudomonas

Country Status (25)

Country Link
US (3) US9987344B2 (el)
EP (2) EP2925355B1 (el)
JP (2) JP6340011B2 (el)
KR (1) KR20150100665A (el)
CN (2) CN105142666A (el)
AU (2) AU2013351182C1 (el)
BR (1) BR112015012762A2 (el)
CA (1) CA2892688A1 (el)
CY (1) CY1119912T1 (el)
DK (1) DK2925355T3 (el)
ES (2) ES2656510T3 (el)
HR (1) HRP20180039T1 (el)
HU (1) HUE036158T2 (el)
IL (2) IL238987B (el)
LT (1) LT2925355T (el)
MX (2) MX366876B (el)
NO (1) NO2925355T3 (el)
PL (1) PL2925355T3 (el)
PT (1) PT2925355T (el)
RS (1) RS56886B1 (el)
RU (2) RU2018137673A (el)
SG (2) SG10201706671WA (el)
SI (1) SI2925355T1 (el)
SM (1) SMT201800011T1 (el)
WO (1) WO2014083060A2 (el)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
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AU2011348396A1 (en) * 2010-12-23 2013-07-04 Valneva Austria Gmbh OprF/I agents and their use in hospitalized and other patients
US20180201656A1 (en) 2015-07-04 2018-07-19 Evaxion Biotech Aps Proteins and nucleic acids useful in vaccines targeting Pseudomonas Aeruginosa
CN105732778A (zh) * 2016-03-02 2016-07-06 中国人民解放军第三军医大学 铜绿假单胞菌重组蛋白OprL及制备方法和应用
CN110922455B (zh) * 2019-12-28 2023-01-13 重庆艾力彼生物科技有限公司 铜绿假单胞菌疫苗重组蛋白rePilA-FliC及制备方法和应用

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Also Published As

Publication number Publication date
BR112015012762A2 (pt) 2017-09-12
ES2826555T3 (es) 2021-05-18
RU2015125699A (ru) 2017-01-11
SG10201706671WA (en) 2017-09-28
MX2019008779A (es) 2019-09-10
MX2015006791A (es) 2016-01-14
KR20150100665A (ko) 2015-09-02
AU2013351182C1 (en) 2018-11-08
US20150322116A1 (en) 2015-11-12
SG11201504258RA (en) 2015-07-30
LT2925355T (lt) 2018-03-26
WO2014083060A2 (en) 2014-06-05
IL238987B (en) 2019-08-29
IL238987A0 (en) 2015-07-30
JP6340011B2 (ja) 2018-06-06
SI2925355T1 (en) 2018-04-30
JP2018135388A (ja) 2018-08-30
WO2014083060A3 (en) 2014-08-28
US9987344B2 (en) 2018-06-05
CN111249455A (zh) 2020-06-09
NO2925355T3 (el) 2018-04-14
AU2013351182A1 (en) 2015-06-18
MX366876B (es) 2019-07-29
US20200360504A1 (en) 2020-11-19
IL267657A (en) 2019-08-29
RU2018137673A (ru) 2019-03-22
CA2892688A1 (en) 2014-06-05
JP2016502533A (ja) 2016-01-28
HRP20180039T1 (hr) 2018-04-06
EP3345617A1 (en) 2018-07-11
AU2018203852B2 (en) 2020-02-27
EP3345617B1 (en) 2020-08-26
ES2656510T3 (es) 2018-02-27
US20180256701A1 (en) 2018-09-13
AU2018203852A1 (en) 2018-06-21
SMT201800011T1 (it) 2018-05-02
AU2013351182B2 (en) 2018-03-08
CN105142666A (zh) 2015-12-09
EP2925355A2 (en) 2015-10-07
RS56886B1 (sr) 2018-04-30
PL2925355T3 (pl) 2018-06-29
HUE036158T2 (hu) 2018-06-28
EP2925355B1 (en) 2017-11-15
DK2925355T3 (en) 2018-01-15
PT2925355T (pt) 2018-02-05

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