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CS211399B2 - Method of making the the new xylite derivatives - Google Patents

Method of making the the new xylite derivatives Download PDF

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Publication number
CS211399B2
CS211399B2 CS793205A CS320579A CS211399B2 CS 211399 B2 CS211399 B2 CS 211399B2 CS 793205 A CS793205 A CS 793205A CS 320579 A CS320579 A CS 320579A CS 211399 B2 CS211399 B2 CS 211399B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
acid
dianhydroxylite
process according
optionally
Prior art date
Application number
CS793205A
Other languages
Czech (cs)
English (en)
Inventor
Ildiko Vidra
Laszlo Institoris
Sandor Eckhard
Karoly Lapis
Andras Jeney
Laszlo Kopper
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of CS211399B2 publication Critical patent/CS211399B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/16Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/62Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/64Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by simultaneous introduction of -OH groups and halogens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63Esters of sulfonic acids
    • C07C309/64Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C07C309/66Methanesulfonates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63Esters of sulfonic acids
    • C07C309/72Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/73Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/34Halogenated alcohols
    • C07C31/42Polyhydroxylic acyclic alcohols
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Epoxy Compounds (AREA)
CS793205A 1978-05-11 1979-05-10 Method of making the the new xylite derivatives CS211399B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU78CI1826A HU176216B (en) 1978-05-11 1978-05-11 Process for producing terminally bifuntional xylite derivatives of citostatic activity

Publications (1)

Publication Number Publication Date
CS211399B2 true CS211399B2 (en) 1982-02-26

Family

ID=10994695

Family Applications (1)

Application Number Title Priority Date Filing Date
CS793205A CS211399B2 (en) 1978-05-11 1979-05-10 Method of making the the new xylite derivatives

Country Status (26)

Country Link
JP (1) JPS5522662A (no)
AR (1) AR222332A1 (no)
AT (1) AT361945B (no)
BE (1) BE876166A (no)
CA (1) CA1145349A (no)
CH (1) CH641437A5 (no)
CS (1) CS211399B2 (no)
DD (1) DD143765A5 (no)
DE (1) DE2917538A1 (no)
DK (1) DK195279A (no)
EG (1) EG15150A (no)
ES (1) ES480869A1 (no)
FI (1) FI67845C (no)
FR (1) FR2425445A1 (no)
GB (1) GB2024204B (no)
GR (1) GR68495B (no)
HU (1) HU176216B (no)
IL (1) IL57182A (no)
IN (1) IN150040B (no)
IT (1) IT1118485B (no)
NL (1) NL7903634A (no)
NO (1) NO153928C (no)
PL (1) PL121560B1 (no)
SE (1) SE7904080L (no)
SU (1) SU984410A3 (no)
YU (1) YU108079A (no)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH381666A (de) * 1958-04-24 1964-09-15 Nat Res Dev Verfahren zur Herstellung von Derivaten von polyhydrischen Alkoholen
DE1668241A1 (de) * 1968-03-06 1971-02-11 Herbrand Kg Dr Therapeutisch wirksame 1,5-di-substituierte Derivate von Xylit,Adonit und Arabit

Also Published As

Publication number Publication date
GB2024204A (en) 1980-01-09
FI791484A (fi) 1979-11-12
FR2425445B1 (no) 1984-06-08
GR68495B (no) 1982-01-07
IL57182A0 (en) 1979-07-25
IT7967984A0 (it) 1979-05-10
IN150040B (no) 1982-07-03
CA1145349A (en) 1983-04-26
NO153928C (no) 1986-06-18
FI67845C (fi) 1985-06-10
HU176216B (en) 1981-01-28
SE7904080L (sv) 1979-11-12
DE2917538A1 (de) 1979-11-15
FR2425445A1 (fr) 1979-12-07
AR222332A1 (es) 1981-05-15
IT1118485B (it) 1986-03-03
SU984410A3 (ru) 1982-12-23
ES480869A1 (es) 1980-06-16
YU108079A (en) 1982-10-31
NO791564L (no) 1979-11-13
JPS5522662A (en) 1980-02-18
EG15150A (en) 1985-12-31
PL215489A1 (no) 1980-02-11
FI67845B (fi) 1985-02-28
PL121560B1 (en) 1982-05-31
GB2024204B (en) 1982-10-27
DD143765A5 (de) 1980-09-10
ATA347779A (de) 1980-09-15
DK195279A (da) 1979-11-12
BE876166A (fr) 1979-09-03
CH641437A5 (de) 1984-02-29
NL7903634A (nl) 1979-11-13
AT361945B (de) 1981-04-10
NO153928B (no) 1986-03-10
IL57182A (en) 1983-07-31

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