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CR11620A - Derivados de Imadazo-[1,2,b]-Piridazina para el Tratamiento de Enfermedad Mediada por Cinosa de Tirosina C-Met - Google Patents

Derivados de Imadazo-[1,2,b]-Piridazina para el Tratamiento de Enfermedad Mediada por Cinosa de Tirosina C-Met

Info

Publication number
CR11620A
CR11620A CR11620A CR11620A CR11620A CR 11620 A CR11620 A CR 11620A CR 11620 A CR11620 A CR 11620A CR 11620 A CR11620 A CR 11620A CR 11620 A CR11620 A CR 11620A
Authority
CR
Costa Rica
Prior art keywords
tyrosine
piridazine
imadazo
derivatives
treatment
Prior art date
Application number
CR11620A
Other languages
English (en)
Inventor
Furet Pascal
Mccarthy Clive
Schoepfer Joseph
Spanka Carsten
Stang Melanie
Stauffer Fruduric
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39672115&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR11620(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CR11620A publication Critical patent/CR11620A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La invencion se refiere a los compuestos de la formula (I) y sales de los mismos, en donde los sustituyentes son como se definen en la memoria descriptiva, a la aplicacion de un compuesto de la formula (I).
CR11620A 2008-02-28 2010-08-06 Derivados de Imadazo-[1,2,b]-Piridazina para el Tratamiento de Enfermedad Mediada por Cinosa de Tirosina C-Met CR11620A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08152068 2008-02-28

Publications (1)

Publication Number Publication Date
CR11620A true CR11620A (es) 2010-10-08

Family

ID=39672115

Family Applications (1)

Application Number Title Priority Date Filing Date
CR11620A CR11620A (es) 2008-02-28 2010-08-06 Derivados de Imadazo-[1,2,b]-Piridazina para el Tratamiento de Enfermedad Mediada por Cinosa de Tirosina C-Met

Country Status (25)

Country Link
US (1) US8822468B2 (es)
EP (1) EP2265614A1 (es)
JP (1) JP5576802B2 (es)
KR (1) KR20100128305A (es)
CN (1) CN102015716B (es)
AR (1) AR070487A1 (es)
AU (1) AU2009218459A1 (es)
BR (1) BRPI0908504A2 (es)
CA (1) CA2717034A1 (es)
CL (1) CL2009000443A1 (es)
CO (1) CO6300957A2 (es)
CR (1) CR11620A (es)
DO (1) DOP2010000263A (es)
EA (1) EA201001365A1 (es)
EC (1) ECSP10010427A (es)
IL (1) IL207434A0 (es)
MA (1) MA32167B1 (es)
MX (1) MX2010009414A (es)
NI (1) NI201000145A (es)
PE (1) PE20091468A1 (es)
SM (1) SMAP201000112A (es)
TW (1) TW200940545A (es)
UY (1) UY31676A1 (es)
WO (1) WO2009106577A1 (es)
ZA (1) ZA201005602B (es)

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UY33597A (es) 2010-09-09 2012-04-30 Irm Llc Compuestos y composiciones como inhibidores de la trk
CA2839958A1 (en) * 2011-06-22 2012-12-27 Knut Eis Heterocyclyl aminoimidazopyridazines
AU2012310168B2 (en) 2011-09-15 2015-07-16 Novartis Ag 6 - substituted 3 - (quinolin- 6 - ylthio) - [1,2,4] triazolo [4, 3 -a] pyradines as tyrosine kinase
CN103958509B (zh) * 2011-09-15 2015-12-23 诺华股份有限公司 作为酪氨酸激酶抑制剂的6-取代的3-(喹啉-6-基硫代)-[1,2,4]三唑并[4,3-a]吡啶化合物
CN103122000B (zh) * 2012-09-03 2013-12-25 中美冠科生物技术（太仓）有限公司 用作抗肿瘤药物的高选择性的c-Met激酶抑制剂
ME03042B (me) 2012-11-19 2018-10-20 Novartis Ag Jedinjenja i kompozicije za tretman parazitskih oboljenja
US9370515B2 (en) 2013-03-07 2016-06-21 Califia Bio, Inc. Mixed lineage kinase inhibitors and method of treatments
AR097543A1 (es) * 2013-09-06 2016-03-23 Lexicon Pharmaceuticals Inc COMPUESTOS BASADOS EN IMIDAZO[1,2-b]PIRIDAZINA, COMPOSICIONES QUE LOS COMPRENDEN Y SUS MÉTODOS DE USO
CN105326793A (zh) * 2014-08-06 2016-02-17 中美冠科生物技术（太仓）有限公司 一种包含c-Met激酶抑制剂的固体分散体及其制备方法和用途
KR20170095243A (ko) * 2014-12-19 2017-08-22 얀센 파마슈티카 엔.브이. Pi3kbeta 저해제로서의 헤테로사이클릴 연결된 이미다조피리다진 유도체
ME03517B (me) * 2014-12-19 2020-04-20 Janssen Pharmaceutica Nv Derivati imidazopiridazina kao pi3kbeta inhibitori
CA3032210A1 (en) * 2016-09-16 2018-03-22 Helmholtz Zentrum Muenchen - Deutsches Forschungszentrum Fur Gesundheit Und Umwelt (Gmbh) Traf 6 inhibitors
EP3558304A2 (en) * 2016-12-23 2019-10-30 Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Inhibitors of cytochrome p450 family 7 subfamily b member 1 (cyp7b1) for use in treating diseases
WO2018138050A1 (de) 2017-01-26 2018-08-02 Bayer Aktiengesellschaft Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel
US11584744B2 (en) * 2017-06-23 2023-02-21 University Of Washington Inhibitors of type 1 methionyl-tRNA synthetase and methods of using them
US20230059009A1 (en) * 2019-12-18 2023-02-23 The Regents Of The University Of California Inhibitors of lin28 and methods of use thereof
CN119081395B (zh) * 2024-09-07 2025-03-18 广东环塑众创实业有限公司 一种耐高温尼龙工程塑料及其制备方法

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Also Published As

Publication number Publication date
MX2010009414A (es) 2010-09-24
CA2717034A1 (en) 2009-09-03
KR20100128305A (ko) 2010-12-07
EA201001365A1 (ru) 2011-04-29
AR070487A1 (es) 2010-04-07
MA32167B1 (fr) 2011-03-01
AU2009218459A1 (en) 2009-09-03
CL2009000443A1 (es) 2010-09-10
JP5576802B2 (ja) 2014-08-20
EP2265614A1 (en) 2010-12-29
TW200940545A (en) 2009-10-01
CO6300957A2 (es) 2011-07-21
PE20091468A1 (es) 2009-10-22
JP2011513279A (ja) 2011-04-28
UY31676A1 (es) 2009-09-30
ZA201005602B (en) 2011-04-28
CN102015716A (zh) 2011-04-13
BRPI0908504A2 (pt) 2015-08-11
IL207434A0 (en) 2010-12-30
NI201000145A (es) 2011-03-02
US20090264406A1 (en) 2009-10-22
ECSP10010427A (es) 2010-09-30
SMAP201000112A (it) 2010-11-12
WO2009106577A1 (en) 2009-09-03
US8822468B2 (en) 2014-09-02
CN102015716B (zh) 2014-09-17
DOP2010000263A (es) 2010-09-30

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Legal Events

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