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BRPI0908504A2 - Compostos derivados de 3-metil-imidazo[1,2-b]piridazina, uso dos mesmos e composição farmacêutica - Google Patents

Compostos derivados de 3-metil-imidazo[1,2-b]piridazina, uso dos mesmos e composição farmacêutica

Info

Publication number
BRPI0908504A2
BRPI0908504A2 BRPI0908504-1A BRPI0908504A BRPI0908504A2 BR PI0908504 A2 BRPI0908504 A2 BR PI0908504A2 BR PI0908504 A BRPI0908504 A BR PI0908504A BR PI0908504 A2 BRPI0908504 A2 BR PI0908504A2
Authority
BR
Brazil
Prior art keywords
methylimidazo
pyridazine
pharmaceutical composition
compounds derived
derived
Prior art date
Application number
BRPI0908504-1A
Other languages
English (en)
Inventor
Pascal Furet
Clive Mccarthy
Joseph Schoepfer
Carsten Spanka
Melanie Stang
Frédéric Stauffer
Original Assignee
Novatis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39672115&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0908504(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novatis Ag filed Critical Novatis Ag
Publication of BRPI0908504A2 publication Critical patent/BRPI0908504A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BRPI0908504-1A 2008-02-28 2009-02-26 Compostos derivados de 3-metil-imidazo[1,2-b]piridazina, uso dos mesmos e composição farmacêutica BRPI0908504A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08152068 2008-02-28
PCT/EP2009/052302 WO2009106577A1 (en) 2008-02-28 2009-02-26 Imidazo [1,2-b] pyridazine derivatives for the treatment of c-met tyrosine kinase mediated disease

Publications (1)

Publication Number Publication Date
BRPI0908504A2 true BRPI0908504A2 (pt) 2015-08-11

Family

ID=39672115

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0908504-1A BRPI0908504A2 (pt) 2008-02-28 2009-02-26 Compostos derivados de 3-metil-imidazo[1,2-b]piridazina, uso dos mesmos e composição farmacêutica

Country Status (25)

Country Link
US (1) US8822468B2 (pt)
EP (1) EP2265614A1 (pt)
JP (1) JP5576802B2 (pt)
KR (1) KR20100128305A (pt)
CN (1) CN102015716B (pt)
AR (1) AR070487A1 (pt)
AU (1) AU2009218459A1 (pt)
BR (1) BRPI0908504A2 (pt)
CA (1) CA2717034A1 (pt)
CL (1) CL2009000443A1 (pt)
CO (1) CO6300957A2 (pt)
CR (1) CR11620A (pt)
DO (1) DOP2010000263A (pt)
EA (1) EA201001365A1 (pt)
EC (1) ECSP10010427A (pt)
IL (1) IL207434A0 (pt)
MA (1) MA32167B1 (pt)
MX (1) MX2010009414A (pt)
NI (1) NI201000145A (pt)
PE (1) PE20091468A1 (pt)
SM (1) SMAP201000112A (pt)
TW (1) TW200940545A (pt)
UY (1) UY31676A1 (pt)
WO (1) WO2009106577A1 (pt)
ZA (1) ZA201005602B (pt)

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US8389526B2 (en) * 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
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IN2012DN01453A (pt) 2009-08-20 2015-06-05 Novartis Ag
PE20130375A1 (es) 2009-12-31 2013-04-10 Hutchison Medipharma Ltd Compuestos de triazolopiridinas y triazolopirazinas inhibidores de c-met y composiciones de los mismos
US20110195066A1 (en) * 2010-02-05 2011-08-11 Auspex Pharmaceuticals, Inc. Quinoline inhibitors of tyrosine kinase
WO2012003338A1 (en) * 2010-07-01 2012-01-05 Takeda Pharmaceutical Company Limited COMBINATION OF A cMET INHIBITOR AND AN ANTIBODY TO HGF AND/OR cMET
AR085183A1 (es) 2010-07-30 2013-09-18 Lilly Co Eli Compuesto 6-(1-metil-1h-pirazol-4-il)-3-(2-metil-2h-indazol-5-iltio)-[1,2,4]triazol[4,3-b]piridazina, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para tratar cancer
US8637516B2 (en) * 2010-09-09 2014-01-28 Irm Llc Compounds and compositions as TRK inhibitors
WO2012175591A1 (en) * 2011-06-22 2012-12-27 Bayer Intellectual Property Gmbh Heterocyclyl aminoimidazopyridazines
CN103958509B (zh) * 2011-09-15 2015-12-23 诺华股份有限公司 作为酪氨酸激酶抑制剂的6-取代的3-(喹啉-6-基硫代)-[1,2,4]三唑并[4,3-a]吡啶化合物
ES2691650T3 (es) 2011-09-15 2018-11-28 Novartis Ag 3-(quinolin-6-il-tio)-[1,2,4]-triazolo-[4,3-a]-piridinas 6-sustituidas como inhibidores de tirosina quinasa c-Met
CN103122000B (zh) * 2012-09-03 2013-12-25 中美冠科生物技术（太仓）有限公司 用作抗肿瘤药物的高选择性的c-Met激酶抑制剂
CN105164124B (zh) 2012-11-19 2017-03-15 诺华股份有限公司 用于治疗寄生虫疾病的化合物和组合物
CA2901427A1 (en) 2013-03-07 2014-09-12 Califia Bio, Inc. Mixed lineage kinase inhibitors and method of treatments
AR097543A1 (es) * 2013-09-06 2016-03-23 Lexicon Pharmaceuticals Inc COMPUESTOS BASADOS EN IMIDAZO[1,2-b]PIRIDAZINA, COMPOSICIONES QUE LOS COMPRENDEN Y SUS MÉTODOS DE USO
CN105326793A (zh) * 2014-08-06 2016-02-17 中美冠科生物技术（太仓）有限公司 一种包含c-Met激酶抑制剂的固体分散体及其制备方法和用途
EP3233862B1 (en) * 2014-12-19 2019-07-03 Janssen Pharmaceutica NV Imidazopyridazine derivatives as pi3kbeta inhibitors
US10202387B2 (en) * 2014-12-19 2019-02-12 Janssen Pharmaceutica Nv Heterocyclyl linked imidazopyridazine derivatives as PI3KB inhibitors
CN109715631B (zh) * 2016-09-16 2022-02-18 德国亥姆霍兹慕尼黑中心健康与环境研究中心（有限公司） Traf 6抑制剂
EP3558304A2 (en) * 2016-12-23 2019-10-30 Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Inhibitors of cytochrome p450 family 7 subfamily b member 1 (cyp7b1) for use in treating diseases
WO2018138050A1 (de) 2017-01-26 2018-08-02 Bayer Aktiengesellschaft Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel
US11584744B2 (en) * 2017-06-23 2023-02-21 University Of Washington Inhibitors of type 1 methionyl-tRNA synthetase and methods of using them
CN115087657B (zh) * 2019-12-18 2025-01-21 加利福尼亚大学董事会 Lin28抑制剂和其使用方法
CN119081395B (zh) * 2024-09-07 2025-03-18 广东环塑众创实业有限公司 一种耐高温尼龙工程塑料及其制备方法

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CA2057089A1 (en) 1990-12-07 1992-06-08 Eric E. Allen Substituted pyrazolopyrimidines and imidazopyridazines as angiotensin ii antagonists
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Also Published As

Publication number Publication date
CO6300957A2 (es) 2011-07-21
ECSP10010427A (es) 2010-09-30
MA32167B1 (fr) 2011-03-01
EP2265614A1 (en) 2010-12-29
TW200940545A (en) 2009-10-01
AR070487A1 (es) 2010-04-07
CN102015716B (zh) 2014-09-17
ZA201005602B (en) 2011-04-28
CA2717034A1 (en) 2009-09-03
MX2010009414A (es) 2010-09-24
NI201000145A (es) 2011-03-02
SMAP201000112A (it) 2010-11-12
CN102015716A (zh) 2011-04-13
DOP2010000263A (es) 2010-09-30
JP2011513279A (ja) 2011-04-28
JP5576802B2 (ja) 2014-08-20
UY31676A1 (es) 2009-09-30
US20090264406A1 (en) 2009-10-22
IL207434A0 (en) 2010-12-30
PE20091468A1 (es) 2009-10-22
CR11620A (es) 2010-10-08
AU2009218459A1 (en) 2009-09-03
CL2009000443A1 (es) 2010-09-10
WO2009106577A1 (en) 2009-09-03
KR20100128305A (ko) 2010-12-07
US8822468B2 (en) 2014-09-02
EA201001365A1 (ru) 2011-04-29

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.