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ECSP099818A - Procesos para la preparacion de pirazoles - Google Patents

Procesos para la preparacion de pirazoles

Info

Publication number
ECSP099818A
ECSP099818A EC2009009818A ECSP099818A ECSP099818A EC SP099818 A ECSP099818 A EC SP099818A EC 2009009818 A EC2009009818 A EC 2009009818A EC SP099818 A ECSP099818 A EC SP099818A EC SP099818 A ECSP099818 A EC SP099818A
Authority
EC
Ecuador
Prior art keywords
processes
pirazoles
preparation
hal
compounds
Prior art date
Application number
EC2009009818A
Other languages
English (en)
Inventor
Martin Charles Bowden
Brian David Gott
David Anthony Jackson
Original Assignee
Syngenta Ltd
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38812166&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP099818(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Syngenta Ltd, Syngenta Participations Ag filed Critical Syngenta Ltd
Publication of ECSP099818A publication Critical patent/ECSP099818A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C07C251/74—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C251/76—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La presente invención se refiere a procesos novedosos para la producción de los compuestos de la fórmula I (consta gráfico) en los cuales Hal y Hal' son en forma independiente CI o F, y R1 es H, CI o F.
EC2009009818A 2007-06-27 2009-12-18 Procesos para la preparacion de pirazoles ECSP099818A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07012546A EP2008996A1 (en) 2007-06-27 2007-06-27 Process for the production of pyrazoles

Publications (1)

Publication Number Publication Date
ECSP099818A true ECSP099818A (es) 2010-01-29

Family

ID=38812166

Family Applications (2)

Application Number Title Priority Date Filing Date
EC2009009817A ECSP099817A (es) 2007-06-27 2009-12-18 Procesos para la preparacion de pirazoles
EC2009009818A ECSP099818A (es) 2007-06-27 2009-12-18 Procesos para la preparacion de pirazoles

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EC2009009817A ECSP099817A (es) 2007-06-27 2009-12-18 Procesos para la preparacion de pirazoles

Country Status (18)

Country Link
US (3) US8269020B2 (es)
EP (3) EP2008996A1 (es)
JP (2) JP2010531315A (es)
KR (2) KR20100025531A (es)
CN (3) CN101687806A (es)
AR (2) AR067355A1 (es)
AU (2) AU2008267472A1 (es)
BR (2) BRPI0813903A2 (es)
CA (2) CA2690246A1 (es)
CL (2) CL2008001896A1 (es)
CO (2) CO6251313A2 (es)
CR (2) CR11161A (es)
EC (2) ECSP099817A (es)
IL (2) IL202419A0 (es)
MX (2) MX2009013591A (es)
RU (2) RU2010102135A (es)
TW (2) TW200914428A (es)
WO (2) WO2009000442A2 (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2008996A1 (en) * 2007-06-27 2008-12-31 Syngeta Participations AG Process for the production of pyrazoles
EP2133341A1 (de) * 2008-02-25 2009-12-16 Bayer CropScience AG Verfahren zur regioselektiven Synthese von 1-Alkyl-3-haloalkyl-pyrazol-4-carbonsäure-Derivaten
CN102164898A (zh) * 2008-09-30 2011-08-24 索尔维公司 用于合成卤化的环状化合物的方法
GB0908435D0 (en) * 2009-05-15 2009-06-24 Syngenta Ltd Processes
WO2012025469A1 (en) * 2010-08-24 2012-03-01 Solvay Sa Improved process for the preparation of esters of 1-h-pyrazole-4-carboxylic acids
FR2975992B1 (fr) * 2011-06-01 2013-11-08 Rhodia Operations Procede de preparation d'un compose fluoromethylpyrazole sous forme acide carboxylique ou derivee
FR2975990B1 (fr) * 2011-06-01 2013-05-24 Rhodia Operations Procede de preparation d'un compose organique fluore
US9145369B2 (en) 2012-05-14 2015-09-29 Bayer Cropscience Ag Process for preparing 1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carboxylic acid chlorides
US8871947B2 (en) 2013-02-04 2014-10-28 KingChem LLC Preparation of alkyl 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid ester
BR112016008697B8 (pt) 2013-10-23 2021-12-21 Bayer Cropscience Ag Método para produzir halocetonas
CN103570623B (zh) * 2013-11-12 2015-05-20 湖南化工研究院 一种3-(二氟甲基)-1-甲基-1h-吡唑-4-羧酸的制备方法
US9139507B2 (en) 2013-12-09 2015-09-22 KingChem LLC. Process for the preparation of alkyl 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylate and its analogs
CN103787977B (zh) * 2014-01-21 2016-05-25 南通雅本化学有限公司 一种空气氧化制备3-氟代烷基-1-取代吡唑-4-羧酸的方法
CN105541716B (zh) 2015-03-26 2024-02-23 Ａｇｃ株式会社 吡唑衍生物的制造方法
WO2016202254A1 (zh) * 2015-06-19 2016-12-22 浙江永太科技股份有限公司 一种用于制备吡唑甲酸衍生物的方法及其中间体
CN104945325B (zh) * 2015-06-19 2017-04-05 浙江永太科技股份有限公司 一种吡唑甲酸衍生物的制备方法
CN106554311B (zh) * 2015-09-28 2019-03-01 常州市卜弋科研化工有限公司 3-氟代烷基-1-甲基吡唑-4-羧酸的制备方法
WO2017054112A1 (zh) * 2015-09-28 2017-04-06 常州市卜弋科研化工有限公司 3-氟代烷基-1-甲基吡唑-4-羧酸的制备方法
PT3797099T (pt) 2018-05-21 2024-02-05 Pi Industries Ltd Método para preparar compostos heterocíclicos substituídos
CN109232425A (zh) * 2018-10-16 2019-01-18 山东省农药科学研究院 一种苯丙烯氟菌唑中间体3-(二氟甲基)-1-甲基-1h-吡唑-4-羧酸的合成方法
CN110577503A (zh) 2019-08-02 2019-12-17 宿迁市科莱博生物化学有限公司 一种卤素取代化合物及其制备方法和应用
CN111303035A (zh) * 2020-03-18 2020-06-19 徐州圣元化工有限公司 一种3-(二氟甲基)-1-甲基-1h-吡唑-4-羧酸的制备方法
CN111233768B (zh) * 2020-03-18 2021-08-03 徐州圣元化工有限公司 一种3-(二氟甲基)-1-甲基-1h-吡唑-4-羧酸乙酯的制备方法
WO2022233129A1 (en) 2021-05-05 2022-11-10 Fujian Yongjing Technology Co., Ltd New process for the synthesis of 5-fluoro-3- (difuoromethyl) -5-fluoro-1-methyl-1h-pyrazole-4-carboxylic acid derivatives and the free acid thereof
CN114195715B (zh) * 2021-12-31 2024-05-10 福建永晶科技股份有限公司 1-甲基-3-二氟甲基-4-吡唑酸和1-甲基-3-三氟甲基-4-吡唑酸的制备方法
CN117384096A (zh) * 2023-12-13 2024-01-12 山东国邦药业有限公司 一种二氟吡唑酸的制备方法
CN117447401B (zh) * 2023-12-26 2024-04-19 山东国邦药业有限公司 一种二氟吡唑酸的合成方法
CN119241439B (zh) * 2024-12-05 2025-03-07 湖南斯派克科技股份有限公司 一种农药中间体二氟吡唑酸的合成方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
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JPH0759557B2 (ja) * 1987-12-25 1995-06-28 三井東圧化学株式会社 １，３−ジアルキルピラゾール−４−アルデヒド誘導体の製造方法
JPH0759558B2 (ja) * 1987-12-25 1995-06-28 三井東圧化学株式会社 １，３−ジアルキルピラゾール−４−アルデヒド類の製造法
JPH089599B2 (ja) * 1988-08-02 1996-01-31 三井東圧化学株式会社 ピラゾールカルボン酸類の製造方法
JP2006519755A (ja) * 2002-11-20 2006-08-31 ロレアル ピラゾール−カルボキシアミドを含有する毛髪の手入れ用又は睫毛用の組成物、毛髪及び睫毛の成長を刺激し、及び／又は抜毛を防止するためのそれらの使用
DE10349500A1 (de) * 2003-10-23 2005-06-02 Bayer Cropscience Ag Verfahren zum Herstellen von 2-Dihalogenacyl-3-amino-acrylsäureestern und 3-Dihalogenmethyl-pyrazol-4-carbonsäureestern
US7521462B2 (en) * 2004-02-27 2009-04-21 Eli Lilly And Company 4-Amino-piperidine derivatives as monoamine uptake inhibitors
EP1761498A1 (de) * 2004-06-18 2007-03-14 Basf Aktiengesellschaft 1-methyl-3-difluormethyl-pyrazol-4-carbonsäure-(ortho-phenyl)-anilide und ihre verwendung als fungizid
PL1781662T3 (pl) * 2004-08-18 2011-08-31 Pfizer Inhibitory zależnej od RNA polimerazy RNA wirusa zapalenia wątroby typu C, i kompozycje i terapie wykorzystujące je
US7863460B2 (en) * 2005-02-25 2011-01-04 Sagami Chemical Research Center Process for producing 1-substituted-3-fluoroalkylpyrazole-4-carboxylate
EP1928838B1 (en) * 2005-09-16 2012-10-24 Syngenta Participations AG Process for the production of amides
AU2008257515B2 (en) * 2007-06-01 2014-01-23 Basf Se Method for the production of n-substituted (3-dihalomethyl-1-methyl-pyrazole-4-YL) carboxamides
EP2008996A1 (en) * 2007-06-27 2008-12-31 Syngeta Participations AG Process for the production of pyrazoles

Also Published As

Publication number Publication date
MX2009013591A (es) 2010-01-20
US8269020B2 (en) 2012-09-18
KR20100025533A (ko) 2010-03-09
JP5563449B2 (ja) 2014-07-30
WO2009000441A8 (en) 2010-01-14
CA2690246A1 (en) 2008-12-31
US20100256390A1 (en) 2010-10-07
US8785657B2 (en) 2014-07-22
US20100240907A1 (en) 2010-09-23
EP2170832A2 (en) 2010-04-07
CN101796021A (zh) 2010-08-04
CN102516175A (zh) 2012-06-27
WO2009000442A2 (en) 2008-12-31
ECSP099817A (es) 2010-01-29
EP2167461A1 (en) 2010-03-31
CO6251314A2 (es) 2011-02-21
CA2689218A1 (en) 2008-12-31
KR20100025531A (ko) 2010-03-09
AU2008267473A1 (en) 2008-12-31
CL2008001896A1 (es) 2009-03-06
RU2010102135A (ru) 2011-08-10
CO6251313A2 (es) 2011-02-21
MX2009013592A (es) 2010-01-20
EP2008996A1 (en) 2008-12-31
WO2009000442A3 (en) 2009-07-23
TW200914428A (en) 2009-04-01
AR067355A1 (es) 2009-10-07
RU2010102137A (ru) 2011-08-10
BRPI0813284B1 (pt) 2017-10-31
EP2167461B1 (en) 2012-08-08
BRPI0813903A2 (pt) 2014-12-30
IL202664A0 (en) 2010-06-30
JP2010531315A (ja) 2010-09-24
US20130023668A1 (en) 2013-01-24
CN101687806A (zh) 2010-03-31
CL2008001897A1 (es) 2009-01-02
CR11162A (es) 2010-04-21
JP2010531314A (ja) 2010-09-24
WO2009000442A8 (en) 2010-01-21
WO2009000441A1 (en) 2008-12-31
CR11161A (es) 2010-05-19
IL202419A0 (en) 2010-06-30
AR067356A1 (es) 2009-10-07
IL202664A (en) 2014-07-31
TW200916445A (en) 2009-04-16
BRPI0813284A2 (pt) 2014-12-30
AU2008267472A1 (en) 2008-12-31
BRPI0813284A8 (pt) 2017-04-04

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