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CN208297537U - Full-automatic chemiluminescence immunoassay analysis meter - Google Patents

Full-automatic chemiluminescence immunoassay analysis meter Download PDF

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Publication number
CN208297537U
CN208297537U CN201820416628.3U CN201820416628U CN208297537U CN 208297537 U CN208297537 U CN 208297537U CN 201820416628 U CN201820416628 U CN 201820416628U CN 208297537 U CN208297537 U CN 208297537U
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China
Prior art keywords
reagent
reaction vessel
sample
cleaning
full
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CN201820416628.3U
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Chinese (zh)
Inventor
许华明
祁云冬
陈旺富
先梦
沈淦松
成志斌
彭建军
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Shenzhen Mindray Bio Medical Electronics Co Ltd
Chengdu Shen Mindray Medical Electronics Technology Research Institute Co Ltd
Original Assignee
Shenzhen Mindray Bio Medical Electronics Co Ltd
Chengdu Shen Mindray Medical Electronics Technology Research Institute Co Ltd
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Abstract

The utility model provides a kind of Full-automatic chemiluminescence immunoassay analysis meter, including sample reagent loading assembly, separate injection needle, mixing seat, incubation survey optical assembly, Magneto separate cleaning assembly and reaction vessel grabbing assembly;The Magneto separate cleaning assembly and the incubation survey optical assembly and are located at the ipsilateral of the sample reagent loading assembly, and the Magneto separate cleaning assembly is surveyed optical assembly with the incubation and is disposed adjacent, the mixing seat is located at the sample reagent loading assembly and the incubation is surveyed between optical assembly;Sample and reagent can be transferred to respectively in the reaction vessel for mixing seat by the separate injection needle;The reaction vessel grabbing assembly is surveyed between optical assembly and the Magneto separate cleaning assembly in the mixing seat, the incubation and transports the reaction vessel.Each components execute above-mentioned steps according to its arrangement, so that structure is simple, it is easy to operate, while package size can also be reduced and to occupy little space, and reduce production cost.

Description

Full-automatic chemiluminescence immunoassay analysis meter
Technical field
The utility model relates to chemiluminescence detection technology fields, more particularly to immune point of a kind of Full-automatic chemiluminescence Analyzer.
Background technique
Chemiluminescence immunoassay technology is worldwide to develop swift and violent a kind of highly sensitive and height nearly ten years The analysis instrument of specificity, for detecting every immune indexes of blood, urine or other body fluid, is somebody's turn to do in clinical labororatory Principle is that the combination of this two technologies of antibody antigen reaction and chemiluminescence is reached high specific and high sensitivity.Chemistry hair Main operating process includes that the dispensing of sample loading, load reagents, sample and reagent, reaction solution mix, are anti-in light analyzer Liquid is answered to be incubated for, Magneto separate cleaning separation, substrate luminescent solution injects and survey light.Currently, chemical illumination immunity analysis instrument is generally deposited Structure is complicated, take up space big, at high cost, the low disadvantage of test flux, influence using.
Utility model content
Based on this, it is necessary to which for current chemical illumination immunity analysis instrument, structure is complicated, occupied space is big, at high cost Problem, provides that a kind of structure is simple, reduces package size and reduces the Full-automatic chemiluminescence immunoassay analysis meter of production cost.
Above-mentioned purpose is achieved through the following technical solutions:
A kind of Full-automatic chemiluminescence immunoassay analysis meter, including the sample reagent loading group for sample loading and reagent Part, the separate injection needle for suction sample and reagent, the mixing seat for mixing, the incubation survey light group for the detection that is incubated for and shines Part, the reaction vessel grabbing assembly for the Magneto separate cleaning assembly of separation cleaning and for transporting reaction vessel;
The Magneto separate cleaning assembly and described be incubated for survey the same side that optical assembly is located at the sample reagent loading assembly, And the Magneto separate cleaning assembly is surveyed optical assembly with the incubation and is disposed adjacent, the mixing seat is located at sample reagent loading Component and the incubation are surveyed between optical assembly;
The separate injection needle is located at the top of the sample reagent loading assembly, and can be transferred to respectively sample with reagent In the reaction vessel for mixing seat;The reaction vessel grabbing assembly surveys optical assembly and institute in the mixing seat, the incubation It states and transports the reaction vessel between Magneto separate cleaning assembly.
The Full-automatic chemiluminescence immunoassay analysis meter further includes carrying platform in one of the embodiments, the sample This load reagents component is located at the right side of carrying platform, and the Magneto separate cleaning assembly is surveyed optical assembly with the incubation and is located side by side at The left rear side of the carrying platform, the reaction vessel grabbing assembly are located at the front side of the carrying platform.
The Magneto separate cleaning assembly is located at the sample reagent loading assembly and incubates with described in one of the embodiments, It educates and surveys between optical assembly, the mixing seat is between the Magneto separate cleaning assembly and the reaction vessel grabbing assembly.
In one of the embodiments, the sample reagent loading assembly include for sample loading annular sample disk with And reagent disc and reagent pot for loaded reagent, the reagent disc are rotatablely arranged in the reagent pot, the annular Sample disk is coaxially sheathed on the outside of the reagent pot, and the annular sample disk rotates independently of each other with the reagent disc.
The sample reagent loading assembly further includes cleaning knot for cleaning the needle of separate injection needle in one of the embodiments, Structure, the needle cleaning structure are set on the annular sample disk, and between two adjacent sample racks.
The sample reagent loading assembly further includes sweeping for the identification code of scanning recognition code in one of the embodiments, Instrument is retouched, is provided with scanning notch on the annular sample disk;
The identification code scanner can scan the identification code of sample container on the annular sample disk, and the identification code is swept The identification code of reagent container in the reagent pot can also be scanned through the scanning notch by retouching instrument.
The identification code scanner is fixedly installed on the outside of the annular sample disk, institute in one of the embodiments, It states annular sample disk the sample container is driven successively to turn at the identification code scanner and be scanned;The scanning notch The corresponding identification code scanner, the reagent disc drive the reagent container successively to turn at the position of the scanning notch It is scanned.
It is described to be formed to there is default spacing between the adjacent two annular sample disks in one of the embodiments, Notch is scanned, there is scanning window, the scanning window, the scanning notch and the identification code scanner on the reagent pot It corresponds to each other, the reagent disc drives multiple reagent container rotations, and the reagent container is made successively to move to the scanning At window, the identification code of reagent container described in the identification code scanner scanning.
The sample reagent loading assembly further includes refrigeration part in one of the embodiments, the refrigeration part position In the lower section of the reagent disc, and deviate the center of the reagent pot, for freezing in the reagent pot.
The sample reagent loading assembly further includes cold end fin and cold end fan in one of the embodiments, described Cold end fin and the cold end fan are set to the cold end of the refrigeration part and are arranged close to the reagent the bottom of a pan, the cold end One end of fin is bonded with the cold end of the refrigeration part, and the cold end fan is set to the other end of the cold end fin Or side, the cold end fan drive the gas in ambient enviroment to flow through the cold end fin.
The sample reagent loading assembly further includes hot-side heat dissipation device and conducting-heat elements, institute in one of the embodiments, It states hot-side heat dissipation device to connect with the hot end of the refrigeration part, and is located at the outside of the reagent pot;The conducting-heat elements and institute State the outside that hot-side heat dissipation device connects and corresponds to the scanning window.
The sample reagent loading assembly further includes the reagent pot for being covered on the reagent pot in one of the embodiments, Lid;The reagent pot cover has multiple suction reagent wells, and multiple reagent wells of inhaling are arranged along the radial direction of the reagent disc pot, And be located in a straight line, the separate injection needle can extend into any suction reagent wells and draw reagent.
The sample reagent loading assembly further includes switch cover in one of the embodiments, is had on the reagent pot cover There is the opening that takes for being placed or taken out reagent container, the switch cover is switchably located at the described of the reagent pot cover and puts Take away mouth.
The reagent pot cover further includes the cold plate and drip tray being oppositely arranged in one of the embodiments, described cold Solidifying plate is detachably connected with the drip tray, and airflow channel is formed between the cold plate and the drip tray, the examination Cold air in agent pot is able to enter the airflow channel;
It is described inhale reagent wells include first on the cold plate inhale reagent wells and on the drip tray the Two inhale reagent wells;The first suction reagent wells are oppositely arranged with the second suction reagent wells, and the wheel of the first suction reagent wells The described second profile for inhaling reagent wells can be completely covered in exterior feature, and the first suction reagent wells are connected with external environment, and described the It is connected in two suction reagent wells and the reagent pot.
The hole wall of the first suction reagent wells extends to form the first ring towards the drip tray in one of the embodiments, The inner wall of shape barrel, the first annular barrel is contacted by the first suction reagent wells with external environment, first ring The outside wall surface of shape barrel is contacted with the airflow channel local environment;
The first annular barrel can be completely covered described second far from one end profile of the first suction reagent wells and inhale The profile of reagent wells.
The hole wall of the second suction reagent wells extends to form the second ring towards the cold plate in one of the embodiments, Shape barrel;
Second annular tube wall inhales reagent wells towards the direction of the cold plate in shrink mouth shape by described second;
There is drainage hole on the drip tray, the bottom of the reagent pot has the drainage channel for draining condensed water, The drainage hole is connected to the drainage channel.
There is sample mixing portion and substrate mixing portion in one of the embodiments, the sample is mixed on the mixing seat Even portion is used to mix sample and examination in the reaction vessel for carrying at least one reaction vessel with sample and reagent Agent, the carrying of substrate mixing portion have the reaction vessel of substrate, and for mixing determinand and bottom in the reaction vessel Object, the mixing seat is able to drive sample mixing portion and substrate mixing portion carries out mixing operation simultaneously.
The Full-automatic chemiluminescence immunoassay analysis meter further includes dispensing punch block in one of the embodiments, and described point Note punch block is located at the rear side above the sample reagent loading assembly, is provided with dispensing driving portion on the dispensing punch block, to drive Move the dispensing needle movement.
The Full-automatic chemiluminescence immunoassay analysis meter further includes separate injection needle swab in one of the embodiments, described Separate injection needle swab is sheathed on the separate injection needle, and can be moved horizontally with the separate injection needle, the separate injection needle swab energy Enough outer wall washings to the separate injection needle.
The Full-automatic chemiluminescence immunoassay analysis meter further includes service sink and for carrying in one of the embodiments, The mixing platform for mixing seat, the service sink are set on the mixing platform, and the service sink is for picking up described point Cleaning waste liquid after infusing needle inner wall washing.
The sample reagent loading assembly, which has, in one of the embodiments, inhales sample station and multiple suction reagent wells, The mixing seat tool has a sample mixing portion, the suction sample station, multiple suction reagent wells, sample mixing portion with it is described Service sink is conllinear.
It includes being incubated for block and surveying light part that optical assembly is surveyed in the incubation in one of the embodiments, and the survey light part is installed In the trailing flank for being incubated for block, described to be incubated on block the multiple incubation holes having in array setting, the incubation hole is for putting It sets the reaction vessel and carries out incubation operation, the reaction vessel after incubation carries out the detection that shines by the survey light part.
Also there is light-measuring hole in one of the embodiments, the light-measuring hole corresponds to the survey light part on the incubation block Setting, and it is located remotely from the side for being incubated for hole, the reaction vessel after incubation is transferred to the survey from the incubation hole In unthreaded hole, and the detection that shines is carried out by the survey light part.
It further includes substrate economizer bank and substrate heat-conducting block that optical assembly is surveyed in the incubation in one of the embodiments, described Substrate economizer bank and the substrate heat-conducting block are all set in the incubation block, and the substrate heat-conducting block is for heating the substrate Substrate in economizer bank.
It further includes cleaning solution preheating container that optical assembly is surveyed in the incubation in one of the embodiments, is had for cleaning solution The entrance and exit of disengaging, the cleaning solution preheating container is set in the incubation block, for heating cleaning solution.
The automatic chemiluminescence immunoassay further includes removal waste fluid component, the row in one of the embodiments, Waste liquid component is liftably set to the left side for being incubated for block.
It includes being incubated for block and surveying light part that optical assembly is surveyed in the incubation in one of the embodiments, is had on the incubation block There are a light-measuring hole and the waste discharge fluid apertures for accommodating the reaction vessel after detection, the light-measuring hole and waste discharge fluid apertures are side by side and phase Neighbour's setting, the removal waste fluid component decline hold the reaction in the light-measuring hole when waste liquid in the reaction vessel is discharged Device shading.
The Magneto separate cleaning assembly is disc-shaped structure, including Magneto separate pedestal, fluid injection in one of the embodiments, Needle, drain needle and magnet;
It is described with manhole appendix and the cleaning solution inlet opening and cleaning solution drainage hole that are sequentially arranged on the Magneto separate pedestal Manhole appendix is for being put into or taking out the reaction vessel to be separated;The Magneto separate pedestal drives the reaction vessel rotation to make The reaction vessel sequentially corresponds to the cleaning solution inlet opening, cleaning solution drainage hole and the manhole appendix;The injection needle setting In the cleaning solution inlet opening, for adding cleaning solution to the reaction vessel;Described in the liftable correspondence of drain needle The setting of cleaning solution drainage hole, the cleaning waste liquid for being discharged in the reaction vessel;
The magnet is set in the Magneto separate pedestal, and is located at the two sides of the reaction vessel rotation path.
The Magneto separate cleaning assembly further includes Magneto separate swab and drain lifting unit, institute in one of the embodiments, Drain lifting unit is stated liftably to be installed on the Magneto separate pedestal;The drain needle is set on the drain lifting unit, The Magneto separate swab is sheathed on the outside of the drain needle, and is located in the cleaning solution drainage hole, the drain lifting unit When driving the drain needle down or up relative to the Magneto separate swab, the Magneto separate swab can be to the drain needle Outer wall washing.
In one of the embodiments, the magnet include the first magnet and the second magnet, first magnet with it is described Second magnet is distributed along the side of the Magneto separate pedestal, and first magnet reacts appearance positioned at described with second magnet The two sides of device rotation path;
The Magneto separate pedestal has the first cleaning position between the cleaning solution inlet opening and the cleaning solution drainage hole, First magnet corresponds to the first cleaning position setting, and institute's second magnet corresponds to the cleaning solution drainage hole setting;
On vertical line direction, the magnetic pole line of first magnet and the angle of vertical line are the first angle, described The magnetic pole line of two magnet and the angle in the vertical line direction are the second angle, wherein first angle and described second Angle is different.
The Magneto separate pedestal has rotary shaft in one of the embodiments, and the Magneto separate pedestal drives described anti- Container is answered to rotate around the rotary shaft;The extending direction of the rotary shaft is parallel with the vertical line, the magnetic of first magnet Straight line intersection where pole line and the extending direction of the rotary shaft.
The magnetic pole line of first magnet is vertical with the vertical line in one of the embodiments, second magnetic The magnetic pole line of iron is parallel with the vertical line.
Also there is at least one between first cleaning position and the cleaning solution drainage hole in one of the embodiments, Second cleaning position, the quantity of first cleaning position are at least two;
The quantity of first magnet is equal to the quantity of first cleaning position, and the quantity of second magnet is equal to described The quantity of second cleaning position and the cleaning solution drainage hole and, and respectively correspond second cleaning position and the cleaning solution drain Hole;
Adjacent first magnet towards described reaction vessel one end magnetism on the contrary, adjacent two second magnetic The pole orientation of iron is opposite.
The cleaning solution inlet opening and the cleaning solution drainage hole are multiple in one of the embodiments, each described Circumferential direction of the cleaning solution inlet opening with each cleaning solution drainage hole along the Magneto separate pedestal replaces placement;
First magnet and the group number of second magnet are equal with the quantity of the cleaning solution inlet opening, each group of institute State the first magnet it is one group corresponding with second magnet described in cleaning solution inlet opening and the cleaning solution drainage hole.
The Magneto separate cleaning assembly further includes magnetic shielding part in one of the embodiments, the magnetic shielding part It is sheathed on the outside of the Magneto separate pedestal, the magnetic field generated for shielding the magnet.
Also there is substrate injection hole in one of the embodiments, the substrate injects hole location on the Magneto separate pedestal Between the manhole appendix and the cleaning solution drainage hole, substrate is added into the reaction vessel through the substrate injection hole.
The Full-automatic chemiluminescence immunoassay analysis meter further includes that two reaction vessels load in one of the embodiments, Component and carrying platform, two reaction vessel loading assemblies are arranged side by side in the front left side of the carrying platform, and are located at The lower section of the reaction vessel grabbing assembly, the reaction vessel grabbing assembly will be described in the reaction vessel loading assemblies Reaction vessel is transferred to the mixing seat.
The Full-automatic chemiluminescence immunoassay analysis meter further includes the waste material that opening is arranged at top in one of the embodiments, Case, the ash can is set to the right side of the reaction vessel loading assembly, and is located under the reaction vessel grabbing assembly The reaction vessel that waste liquid is discharged is put into the ash can by the opening by side, the reaction vessel grabbing assembly.
The Magneto separate cleaning assembly has substrate injection hole in one of the embodiments, and optical assembly is surveyed in the incubation With substrate economizer bank, the Full-automatic chemiluminescence immunoassay analysis meter further includes two substrate loading parts, and the substrate loads Portion is located at the front side of the sample reagent loading assembly, for carrying substrate container, and passes through pipeline for the bottom in substrate container Object is transported in the reaction vessel after substrate economizer bank preheating by the substrate injection hole.
The Full-automatic chemiluminescence immunoassay analysis meter further includes substrate constant displacement pump in one of the embodiments, described Substrate constant displacement pump is set to the front side of the sample reagent loading assembly, and is respectively communicated with the substrate container, institute by pipeline Substrate economizer bank and the substrate injection hole are stated, provides power for the conveying of substrate.
In one of the embodiments, the Full-automatic chemiluminescence immunoassay analysis meter further include the first divide syringe and Carrying platform, first divide syringe are located at the rear side of the carrying platform, and first divide syringe passes through respectively Pipeline is connected to the separate injection needle and the separate injection needle swab, and cleaning solution is supplied to the separate injection needle and the separate injection needle is wiped Son.
The Full-automatic chemiluminescence immunoassay analysis meter further includes the second divide syringe in one of the embodiments, Second divide syringe is connected between first divide syringe and the separate injection needle, and is located at the carrying The rear side of platform makes the separate injection needle suction sample or reagent.
The Magneto separate cleaning assembly includes Magneto separate swab and injection needle in one of the embodiments, it is described it is complete from Dynamic chemical illumination immunity analysis instrument further includes Magneto separate syringe and carrying platform, and the Magneto separate syringe is located at the carrying The left side of platform, the Magneto separate syringe are connect with the injection needle by pipeline, cleaning solution are delivered to the reaction In container, the Magneto separate syringe also passes through pipeline and connect with the Magneto separate swab, and cleaning solution is supplied to the magnetic point From swab.
The Full-automatic chemiluminescence immunoassay analysis meter further includes vacuum chamber, the first vacuum in one of the embodiments, Pump and carrying platform, the vacuum chamber and first vacuum pump are located at the rear side of carrying platform, the outlet of the vacuum chamber and The first vacuum pump connection, the vacuum chamber inlet are connect by pipeline with Magneto separate cleaning assembly, are by the vacuum chamber The discharge that waste liquid is cleaned in the reaction vessel after the Magneto separate cleaning assembly cleaning provides power, and the vacuum chamber enters Mouth is also surveyed optical assembly with the incubation by pipeline and is connect, and is that incubation survey optical assembly carries out the detection that shines by the vacuum chamber The discharge of waste liquid provides power afterwards.
The Magneto separate cleaning assembly further includes Magneto separate swab and drain needle, the magnetic in one of the embodiments, Separation swab is sheathed on outside the drain needle, and first vacuum pump also passes through pipeline and connect with the Magneto separate swab, is The discharge of cleaning waste liquid provides power in the Magneto separate swab.
The Full-automatic chemiluminescence immunoassay analysis meter further includes the second vacuum pump, dispensing in one of the embodiments, Needle swab, service sink and carrying platform, second vacuum pump are located at the rear side of the carrying platform, second vacuum pump point It is not connect with the separate injection needle swab and the service sink, is the row for cleaning waste liquid in the separate injection needle swab and the service sink Power is provided out.
After adopting the above technical scheme, the utility model has the following beneficial effects:
When the Full-automatic chemiluminescence immunoassay analysis meter of the utility model detects sample, separate injection needle is in sample reagent Sample and reagent are drawn in loading assembly respectively and is transferred in the reaction vessel for mixing seat respectively, after mixing, reaction vessel is grabbed It takes component that reaction vessel is transferred to incubation survey optical assembly again and carries out incubation operation, after the completion of incubation, Magneto separate cleaning assembly pair Reaction vessel carries out separation cleaning, after the completion of cleaning, is incubated for survey optical assembly and carries out the detection that shines to reaction vessel, to obtain sample Various parameters;The incubation of the Full-automatic chemiluminescence immunoassay analysis meter of the utility model surveys optical assembly for sample storage and reagent Store it is integrally disposed, will be incubated for shine detection it is integrally disposed, each components according to its arrangement execution above-mentioned steps, energy The current chemical illumination immunity analysis instrument problem that structure is complicated, occupied space is big, at high cost of enough effective solutions, so that entirely certainly The structure of dynamic chemical illumination immunity analysis instrument is simple, easy to operate, while can also reduce package size and to occupy little space, and It reduces production cost and facilitates operator so that Full-automatic chemiluminescence immunoassay analysis meter is easily achieved miniaturization It uses.
Detailed description of the invention
Fig. 1 is the overlooking structure diagram of the Full-automatic chemiluminescence immunoassay analysis meter of an embodiment of the present invention;
Fig. 2 is the top view of sample reagent loading assembly in Full-automatic chemiluminescence immunoassay analysis meter shown in FIG. 1;
Fig. 3 is the decomposition diagram of sample reagent loading assembly shown in Fig. 2;
Fig. 4 is the schematic diagram that the scanning recognition code of code scanner is identified in sample reagent loading assembly shown in Fig. 2;
Fig. 5 is the structural schematic diagram in sample reagent loading assembly shown in Fig. 3 inside reagent pot;
Fig. 6 is the structural schematic diagram in sample reagent loading assembly shown in Fig. 3 outside reagent pot;
Fig. 7 is the cross-sectional view of reagent loader mechanism in sample reagent loading assembly shown in Fig. 3;
Fig. 8 is the cross-sectional view of condensation structure in sample reagent loading assembly shown in Fig. 3;
Fig. 9 is the schematic diagram that component is dispensed in Full-automatic chemiluminescence immunoassay analysis meter shown in FIG. 1;
Figure 10 is the schematic diagram that component is mixed in Full-automatic chemiluminescence immunoassay analysis meter shown in FIG. 1;
Figure 11 is that the schematic diagram for surveying optical assembly is incubated in Full-automatic chemiluminescence immunoassay analysis meter shown in FIG. 1;
Figure 12 is the schematic diagram of Magneto separate cleaning assembly in Full-automatic chemiluminescence immunoassay analysis meter shown in FIG. 1;
Figure 13 is the schematic diagram of the station in Magneto separate cleaning assembly shown in Figure 12 on Magneto separate pedestal;
Figure 14 is the fluid path schematic diagram that substrate conveys liquid channel system in the fluid path component of an embodiment of the present invention;
Figure 15 is the horizontal distribution that transhipment path expands into the first magnetic part and the second magnetic part after straight line shown in Figure 13 The expanded view of schematic diagram;
Figure 16 is the fluid path schematic diagram that liquid channel system is dispensed in the fluid path component of an embodiment of the present invention;
Figure 17 is the fluid path schematic diagram that Magneto separate cleans liquid channel system in the fluid path component of an embodiment of the present invention;
Figure 18 is the left view of Full-automatic chemiluminescence immunoassay analysis meter shown in FIG. 1;
Figure 19 is the rearview of Full-automatic chemiluminescence immunoassay analysis meter shown in FIG. 1.
Wherein:
1- sample reagent loading assembly;
11- sample loader mechanism;111- sample rack;1111- scans notch;The chassis 112-;113- sample loads driving knot Structure;114- needle cleaning structure;
12- load reagents mechanism;121- reagent pot;1211- scanning window;1212- drainage channel;1213- transparency window; 122- reagent disc;123- reagent pot cover;1231- inhales reagent wells;12311- first inhales reagent wells;12312- second inhales reagent wells; 124- switch cover;125- condensation structure;1251- cold plate;1252- drip tray;The first annular barrel of 1253-;1254- second Annular tube wall;126- reagent storage driving structure;127- refrigeration structure;128- hot-side heat dissipation device;1281- conducting-heat elements;1282- Hot-side heat dissipation piece;The hot end 1283- fan;
13- identifies code scanner;
2-, which is incubated for, surveys optical assembly;
21- sample incubation mechanism;211- is incubated for block;2111- is incubated for hole;2112- light-measuring hole;2113- waste discharge fluid apertures;212- Substrate preheating structure;213- cleaning solution preheating container;
22- surveys light part;
3- dispenses component;
31- separate injection needle;
32- vertical motion mechanism;
33- horicontal motion mechanism;
34- separate injection needle swab;
35- second dispenses wiper mechanism;
4- Magneto separate cleaning assembly;
41- Magneto separate pedestal;411- manhole appendix;412- cleaning solution inlet opening;413- cleaning solution drainage hole;414- first is clear Wash position;The second cleaning position 415-;
42- cleaning solution injecting mechanism;
43- cleaning solution output mechanism;
44- Magneto separate swab;
45- drain lifting unit;
46- substrate injection hole;
47- magnetic shielding part;
48- Magneto separate adsorbing mechanism;The first magnetic part of 481-;The second magnetic part of 482-;
5- reaction vessel grabbing assembly;
6- mixes component;
61- mixes driving mechanism;
62- sample mixing portion;
63- substrate mixing portion;
64- mixing mechanism;
7- removal waste fluid component;
8- fluid path component;
81- dispenses liquid channel system;811- dispenses suction pipeline;812- first dispenses detergent line;813- second is dispensed clearly Wash pipeline;814- first dispenses drain line;815- second dispenses drain line;The first divide syringe of SR1-;SR55- second Vacuum pump;V811- first dispenses control valve;V812- second dispenses control valve;V813- third dispenses control valve;V814- the 4th Dispense control valve;The second divide syringe of SR6-;
82- substrate conveys liquid channel system;821- substrate suction pipe;822- substrate discharge line;SR3- substrate constant displacement pump; V821- the first substrate control valve;V822- the second substrate control valve;
83- Magneto separate cleans liquid channel system;831- Magneto separate imbibition pipeline;832- Magneto separate fluid injection pipeline;833- magnetic point From drain line;834- the first Magneto separate detergent line;835- recovery pipe;836- the second Magneto separate detergent line;SR4- magnetic Separate syringe;SR5- magnetic Magneto separate driving source;SR51- vacuum chamber;SR52- B/P EGR Back Pressure Transducer EGR;The first vacuum pump of SR53-; V831- the first Magneto separate control valve;V832- the second Magneto separate control valve;V833- third Magneto separate control valve;V834- the 4th Magneto separate control valve;The 5th Magneto separate control valve of V835-;The 6th Magneto separate control valve of V836-;The control of the 7th Magneto separate of V837- Valve;
9- reaction vessel loading assembly;
10- power supply module;
77- main control component;
88- cleaning solution detection part;
99- ash can.
Specific embodiment
In order to make the purpose of the utility model, technical solutions and advantages more clearly understood, by the following examples, it and ties Attached drawing is closed, the Full-automatic chemiluminescence immunoassay analysis meter of the utility model is further elaborated.It should be appreciated that herein Described specific embodiment only to explain the utility model, is not used to limit the utility model.
It is herein component institute serialization number itself, such as " first ", " second " etc., is only used for distinguishing described object, Without any sequence or art-recognized meanings.And " connection ", " connection " described in the application, unless otherwise instructed, include directly and It is indirectly connected with (connection).In the description of the present invention, it should be understood that term " on ", "lower", "front", "rear", The orientation or position of the instructions such as "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outside", " clockwise ", " counterclockwise " Setting relationship is to be based on the orientation or positional relationship shown in the drawings, and is merely for convenience of describing the present invention and simplifying the description, and It is not that the component of indication or suggestion meaning or element must have a particular orientation, be constructed and operated in a specific orientation, therefore It should not be understood as limiting the present invention.
In the present invention unless specifically defined or limited otherwise, fisrt feature is in the second feature " on " or " down " It can be that the first and second features directly contact or the first and second features are by intermediary mediate contact.Moreover, first is special Sign can be fisrt feature above the second feature " above ", " above " and " above " and be directly above or diagonally above the second feature, or only Indicate that first feature horizontal height is higher than second feature.Fisrt feature under the second feature " below ", " below " and " below " can be with It is that fisrt feature is directly under or diagonally below the second feature, or is merely representative of first feature horizontal height less than second feature.
Referring to Fig. 1, the utility model provides a kind of Full-automatic chemiluminescence immunoassay analysis meter, which exempts from Epidemic disease analyzer is used to carry out analysis detection to sample to be measured to satisfy the use demand to obtain corresponding testing result.It needs Bright, the specific type of sample to be measured is unrestricted, in some embodiments, sample to be measured include solid sample or Liquid sample.It is appreciated that needing to be placed in sample by the containers such as test tube carrying liquid sample when detecting liquid sample It just can be carried out on this.Further liquid sample includes but is not limited to blood sample.Use the full-automation of the utility model When luminescence immunoassay instrument detects blood sample, blood sample is loaded into test tube, and is subsequently placed at rack for test tube On.The structure of the Full-automatic chemiluminescence immunoassay analysis meter of the utility model is simple, easy to operate, while can also reduce complete machine ruler It is very little and to reduce production cost so that occupy little space so that Full-automatic chemiluminescence immunoassay analysis meter be easily achieved it is small-sized Change development, operator is facilitated to use.
In the present invention, Full-automatic chemiluminescence immunoassay analysis meter includes sample reagent loading assembly 1, dispensing component 3, seat is mixed, is incubated for and surveys optical assembly 2, reaction vessel grabbing assembly 5 and Magneto separate cleaning assembly 4.Sample reagent loading assembly 1 is used In sample loading and reagent.Specifically, sample reagent loading assembly 1 can store a variety of samples.It is understood that sample tries Sample in agent loading assembly 1 can be added manually by operator, it is possible to use automatic sampling component adds sample automatically. Sample reagent loading assembly 1 can also sample loading detection when required various reagents, reagent needed for facilitating selection improves Draw the efficiency of reagent.Dispensing component 3 includes separate injection needle 31, and separate injection needle 31 is used for suction sample and reagent, to realize sample Or agent transfer is into reaction vessel.It mixes seat and is used to support reaction vessel.It is understood that empty reaction vessel is transferred To mixing in seat, component 3 is dispensed respectively by sample and agent transfer into reaction vessel, is mixed sample and reagent by mixing seat After closing uniformly, reaction vessel is transferred to incubation and is surveyed in optical assembly 2.It is incubated for and surveys optical assembly 2 for being incubated for and the detection that shines, magnetic point Separation cleaning is used for from cleaning assembly 4.After reaction vessel is transferred to incubation survey optical assembly 2, being incubated for survey optical assembly 2 can be to anti- Sample and reagent in container is answered to be incubated for, the reaction vessel after incubation is transferred to Magneto separate cleaning assembly 4 and is separated Cleaning, the reaction vessel after cleaning are transferred back in incubation survey optical assembly 2 again and carry out the detection that shines, to obtain the corresponding ginseng of sample Number.Reaction vessel grabbing assembly 5 is used for transfer reaction container, specifically, reaction vessel grabbing assembly 5 is mixing seat, is being incubated for and surveys Reaction vessel is transported between optical assembly 2 and Magneto separate cleaning assembly 4.
Understanding to sample and each stage name of reagent for convenience, herein to the title of sample and reagent each stage Be described in detail: the sample in reaction vessel is known as mixture after mixing with reagent, and being incubated for survey optical assembly 2 can be in reaction vessel Mixture carry out incubation operation so that sample is sufficiently reacted with reagent, at this point, the substance in reaction vessel is determinand and miscellaneous Matter.Wherein, mixture refers to that ratio, the concentration of the substance formed after sample is mixed with reagent and sample and reagent are unrelated, herein Referred to as mixture.Mixture after incubation is presented in a manner of determinand and impurity in the reaction vessel.Impurity can be inabundant The substance of reaction, or the side reaction product that side reaction generates occurs, survey optical assembly 2 can also be incubated for for other influences and is examined Substance of survey etc., or be above-mentioned at least two composition.Magneto separate cleaning assembly 4 in reaction vessel determinand with Impurity is cleaned, to remove the impurity in reaction vessel, so that only existing determinand in reaction vessel.It is incubated for and surveys optical assembly 2 It is able to detect determinand in reaction vessel, to obtain the parameters of sample.If adding bottom in reaction vessel after to separation cleaning Object, i.e. substrate are mixed with determinand, since substrate will not change the attribute of determinand, only increase the luminous value of determinand, institute Determinand is still referred to as after mixing with substrate with determinand.Moreover, the utility model holds separate injection needle 31 and reaction using cleaning solution Determinand in device is cleaned with impurity, and the cleaning solution after cleaning referred to as cleans waste liquid.
Magneto separate cleaning assembly 4 and incubation survey optical assembly 2 and are located at the ipsilateral of sample reagent loading assembly 1, and Magneto separate is clear Wash component 4 be incubated for survey optical assembly 2 be disposed adjacent, mix seat be located at sample reagent loading assembly 1 and be incubated for survey optical assembly 2 it Between.Reaction vessel is transferred to and mixes on seat by reaction vessel grabbing assembly 5, and the separate injection needle 31 of dispensing component 3 is located at sample reagent The top of loading assembly 1, and sample and reagent can be transferred to respectively in the reaction vessel for mixing seat.It mixes seat and is located at sample The motion path that dispensing component 3 can be reduced between optical assembly 2 is surveyed in load reagents component 1 and incubation, and then shortens dispensing component 3 The distance of sample and reagent is shifted, to reduce the transfer time of sample and reagent, improves Full-automatic chemiluminescence immunoassay analysis meter Processing speed.Moreover, Magneto separate cleaning assembly 4 is disposed adjacent with survey optical assembly 2 is incubated for, reaction vessel can be shortened in this way and existed Magneto separate cleaning assembly 4 and the transfer path being incubated between survey optical assembly 2, improve treatment effeciency, and then improve full-automatic chemical The processing speed of luminescence immunoassay instrument.
Sample reagent loading assembly 1, which has, to be inhaled sample station and inhales reactant station, and dispensing component 3 is inhaled in suction sample station It samples after the sample in this load reagents component 1 and is transferred in the reaction vessel for mixing seat, dispensing component 3 is also inhaling reagent work After reagent in position absorption sample reagent loading assembly 1 and it is transferred in the reaction vessel for mixing seat.It is understood that sample With agent transfer in principle without sequencing requirement, it can transfering reagent after sample is first shifted, it can also first transfering reagent After shift sample.
Reaction vessel is transferred to and mixes on seat by reaction vessel grabbing assembly 5, after having added sample and reagent, reaction vessel The reaction vessel for having added sample and reagent is transferred to incubation survey optical assembly 2 from mixing seat and is incubated for by grabbing assembly 5, is reacted Reaction vessel after incubation is also transferred to Magneto separate cleaning assembly 4 and carries out separation cleaning by container grabbing assembly 5, and will be separated clear Reaction vessel after washing is transferred in incubation survey optical assembly 2 and carries out the detection that shines.Sample and reagent in reaction vessel are mixing Mixture is formed on seat, reaction vessel is transferred on incubation survey optical assembly 2 by following reaction container grabbing assembly 5 from seat is mixed, Be incubated for survey optical assembly 2 mixture in reaction vessel is incubated for so that mixture formed in the reaction vessel determinand and Impurity;Then reaction vessel is surveyed in optical assembly 2 from incubation and is transferred in Magneto separate cleaning assembly 4 by reaction vessel grabbing assembly 5, The impurity in reaction vessel is cleaned into removal by Magneto separate cleaning assembly 4, leaves determinand;Reaction vessel grabbing assembly 5 is again Reaction vessel after cleaning is transferred to incubation to survey in optical assembly 2, surveys optical assembly 2 to the determinand in reaction vessel by being incubated for It is detected, to obtain the parameters of sample.
Moreover, sample reagent loading assembly 1 can not only sample loading but also storing reagent, in this way can be by sample loading module It is integrated with reagent memory module, reduces the space occupied when sample loading module is separately provided with reagent memory module, So that sample reagent loading assembly 1 is small in size;Survey optical assembly 2 is incubated for be integrated in incubation function module and detection function module Together, to reduce the space occupied when incubation function module and detection function module are separately provided.In this way, Full-automatic chemiluminescence The all parts of immunity analysis instrument using above-mentioned layout arrangement cooperation function integration after, enable to complete machine rational and compact, Compact, moreover it is possible to which use convenient for the user to operate maintains easily.
The Full-automatic chemiluminescence immunoassay analysis meter of the utility model is for detecting the luminous value of determinand, to obtain Sample this parameters.In order to increase luminous value when analyte detection to be measured, the Full-automatic chemiluminescence of the utility model is immune Analyzer adds substrate in the reaction vessel after separation cleaning, and substrate is attached on determinand, can increase the hair of determinand Light value guarantees the accuracy of pattern detection.Specifically, having substrate container, substrate in Full-automatic chemiluminescence immunoassay analysis meter Container adds substrate into reaction vessel through Magneto separate cleaning assembly 4 by fluid path component 8 for containing substrate.In this way can The structure setting that reaction vessel is carried when reducing addition substrate reduces the transfer number of reaction vessel, and then reduces machine volume. After Magneto separate cleans, substrate is added into reaction vessel, so that substrate is mixed with determinand, then by reaction vessel from Magneto separate Cleaning assembly 4 is transferred to incubation and surveys in optical assembly 2, is carried out again by incubation survey optical assembly 2 to determinand after being incubated for luminous Detection, to obtain the parameters of sample.
Referring to Fig. 1, Figure 17 to Figure 19, as an embodiment, Full-automatic chemiluminescence immunoassay analysis meter further includes Carrying platform, sample reagent loading assembly 1 are located at the right side of carrying platform, are incubated for and survey optical assembly 2, Magneto separate cleaning assembly 4 simultaneously The left rear side in carrying platform is ranked, reaction vessel grabbing assembly 5 is located at the front side of carrying platform.Carrying platform plays carrying and makees With, and by mixing seat supports, placement space is provided for each structure of Full-automatic chemiluminescence immunoassay analysis meter.Specifically, Sample reagent loading assembly 1, mixing seat, incubation are surveyed optical assembly 2, Magneto separate cleaning assembly 4 etc. and are all set on carrying platform, and The fluid path component 8 of Full-automatic chemiluminescence immunoassay analysis meter is located at the lower section of carrying platform, moreover, connecting with fluid path component 8 respectively Kind liquid storage container, waste fluid container etc. are all set in the lower section of carrying platform, can make full use of space in this way, so that full-automatic The machine volume for learning luminometer is small.
It is understood that defining the side of user's operation Full-automatic chemiluminescence immunoassay analysis meter as before carrying platform Side, correspondingly, rear side of the side opposite with the front side of carrying platform for carrying platform, adjacent with the front side of carrying platform two Side is the left and right sides of carrying platform.Specifically, carrying is flat as shown in Figure 1, carrying platform has left side, right side, front side and rear side The right side of platform is sample reagent directorial area, and left side is that reaction vessel dispatches reaction detection area, and rear side is auxiliary Support.Wherein, Substrate container is placed in the forefront of the sample reagent directorial area on right side, and sample reagent loading assembly 1 is set to the sample examination on right side In agent directorial area, and it is located at the rear side of substrate container.Dispensing component 3 is located at the top of sample reagent loading assembly 1, mixes seat In the left side of sample reagent loading assembly 1.The transfer path of sample and reagent can be shortened in this way, improve transfer efficiency, and It also can be reduced occupied space, and then reduce machine volume.The left side of carrying platform is that reaction vessel dispatches reaction detection area, specifically Explained later.Reaction vessel grabbing assembly 5 is located at the front left side of carrying platform, and the moving region of reaction vessel grabbing assembly 5 Optical assembly 2, Magneto separate cleaning assembly 4 and mixing seat etc. are surveyed in the incubation that reaction vessel scheduling reaction detection area can be covered, and are realized The transfer of reaction vessel is incubated for survey optical assembly 2 and is disposed adjacent with seat is mixed, and Magneto separate cleaning assembly 4 and incubation survey optical assembly 2 simultaneously Row is set to the left area of carrying platform.The gas-liquid road and circuit of the rear portion of carrying platform and bottom setting support complete machine operation System, the purpose being arranged in this way is: will likely parts to be maintained be put into as far as possible complete machine periphery, reduce in the future in client Hold the maintenance complexity being likely to occur.
Further, Magneto separate cleaning assembly 4 is located at sample reagent loading assembly 1 and is incubated for and surveys between optical assembly 2, mixes Seat is between Magneto separate cleaning assembly 4 and reaction vessel grabbing assembly 5.In the present embodiment, it is L-shaped to be incubated for survey optical assembly 2 Setting, Magneto separate cleaning assembly 4 are located at L-shaped incubation and survey 2 indentation, there of optical assembly, mix seat and are located at Magneto separate cleaning assembly 4, incubate It educates survey optical assembly 2 and sample reagent loading assembly 1 encloses in the space being set as, reducing reaction vessel transfer path and separate injection needle While 31 transfer path, additionally it is possible to reduce the space occupied, reduce machine volume.
After the Full-automatic chemiluminescence immunoassay analysis meter of the utility model uses above-mentioned layout, sample and reagent can be shortened Transfer path, the transfer path that shortens reaction vessel improve the treatment effeciency to sample, in turn so that compact integral structure Improve the speed of service of complete machine.Moreover, the Full-automatic chemiluminescence immunoassay analysis meter of the utility model is in sample container quantity, examination Under agent container quantity and the nondecreasing situation of reaction vessel quantity, integrated by being cleverly laid out with intermodule function, so that whole Machine rational and compact, compact together, while it being also easy to user's operation use, it maintains easily.
Referring to Fig. 1, Figure 14, Figure 16 to Figure 19, further, the Full-automatic chemiluminescence immunoassay analysis meter of the utility model Further include fluid path component 8, fluid path component 8 can be realized in Full-automatic chemiluminescence immunoassay analysis meter the input of required fluid with it is defeated Out.Fluid path component 8 is connect with dispensing component 3 and Magneto separate cleaning assembly 4 respectively, and fluid path component 8 is for controlling dispensing component 3 Suction sample or reagent and for clean dispensing component 3, fluid path component 8 be also used to Magneto separate cleaning assembly 4 inject or arrange Cleaning solution out.Specifically, fluid path component 8 can control the sample in the dispensing absorption sample reagent loading assembly 1 of component 3, then The sample of absorption is transferred in reaction vessel by control dispensing component 3;Fluid path component 8 can control dispensing component 3 and draw sample Reagent in load reagents component 1, then control dispensing component 3 is by the agent transfer of absorption into reaction vessel.Due to each After drawing sample and reagent, dispensing on component 3 has residue, can there are problems that polluting sample and reagent, therefore, fluid path Component 8 can also convey cleaning solution to clean to dispensing component 3, and the waste liquid after cleaning is discharged.Fluid path component 8 can also It controls Magneto separate cleaning assembly 4 and injects cleaning solution to reaction vessel, after separation cleaning, it is clear that fluid path component 8 also can control Magneto separate It washes component 4 and cleaning solution is discharged from reaction vessel.It is connect in addition, fluid path component 8 also surveys optical assembly 2 with incubation, for being discharged It is incubated for and surveys the waste liquid that optical assembly 2 is tested.That is, first will test the waste liquid discharge in rear reaction vessel, then pass through reaction Container grabbing assembly 5 abandons empty, discarded reaction vessel, can be avoided waste liquid sinuous flow in this way and pollutes.Certainly, in this reality With in novel other embodiments, the reaction vessel with waste liquid after can also directly will test by reaction vessel grabbing assembly 5 It abandons.It is understood that connection refers to through piping connection between certain components of fluid path component 8, it is not detailed one by one herein It states.
Referring to Fig. 1, optionally, Full-automatic chemiluminescence immunoassay analysis meter further includes two reaction vessel loading assemblies 9, instead It answers container loading assembly 9 that the front left side in carrying platform is arranged side by side, and is located at the lower section of reaction vessel grabbing assembly 5, reaction Reaction vessel in reaction vessel loading assembly 9 is transferred to and mixes in seat by container grabbing assembly 5.Specifically, reaction vessel fills It carries component 9 and is located at reaction vessel scheduling reaction detection area, and be located at one for being incubated for and surveying optical assembly 2 far from Magneto separate cleaning assembly 4 Transfer efficiency is improved for carrying and conveying reaction vessel automatically in side.Certainly, in the other embodiments of utility model, instead It answers container loading assembly 9 that can also be replaced, i.e., does not use reaction vessel loading assembly 9 to convey reaction vessel, reaction vessel can It is surveyed in optical assembly 2 with being placed directly into be incubated for.Preferably, the reaction vessel that reaction vessel loading assembly 9 conveys is usually primary Property consumptive material, certainly, reaction vessel can also be recovered recycling.Optionally, it when reaction vessel reuses, can not also use Reaction vessel loading assembly 9 conveys reaction vessel.Moreover, reaction vessel, which refers to, carries and is able to carry out sample reaction, detection point The consumptive material of analysis, such as reaction cup, test tube, sample slide, sample tube.In the present embodiment, reaction vessel refers to reaction cup, reaction Container loading assembly 9 usually transmits reaction vessel box, has the reaction cup in matrix form distribution in reaction vessel box.
Reaction vessel loading assembly 9 is drawer-type structure, i.e. reaction vessel loading assembly 9 can be from Full-automatic chemiluminescence Extract or be pushed into Full-automatic chemiluminescence immunoassay analysis meter in immunity analysis instrument out.Specifically, when Full-automatic chemiluminescence is immune After all parts on analyzer are provide with by outer cover, lower section on front side of carrying platform reaction vessel loading assembly 9 is extracted out or Push-in.When reaction vessel loading assembly 9 is extracted out, the reaction for turning full reaction vessel can be loaded into reaction vessel loading assembly 9 Container;After the completion of the box-packed load of reaction vessel, reaction vessel loading assembly 9 is pushed into, enables reaction vessel loading assembly 9 Automatic transmission reaction vessel.Reaction vessel loading assembly 9 promotes reaction vessel box, so that reaction vessel box is located at reaction vessel The top of loading assembly 9 can grab the hollow reaction vessel of reaction vessel box at this time and be transferred in mixing seat.It is understood that It is that the reaction vessel box in reaction vessel loading assembly 9 can be placed on supporting plate using overlapped way, and pass through driving motor It drives supporting plate to move up and down, realizes the promotion of reaction vessel box, facilitate crawl reaction vessel.Driving motor passes through synchronous belt knot Structure, chain drive structure or other structures realize elevating movement.
Moreover, two reaction vessel loading assemblies 9 are used interchangeably.When in one of reaction vessel loading assembly 9 After reaction vessel has been crawled, extraction container loading assembly 9 is needed to fill the reaction vessel box of reaction vessel, this When, another reaction vessel loading assembly 9 can continue to Full-automatic chemiluminescence immunoassay analysis meter convey reaction vessel, avoid because Reaction vessel loading assembly 9 is unloaded and influences the operation of Full-automatic chemiluminescence immunoassay analysis meter, so that Full-automatic chemiluminescence Immunity analysis instrument can be carried out continuously pattern detection, improve efficiency.
Optionally, the bottom of reaction vessel loading assembly 9 has detection sensor, for detecting reaction vessel loading assembly Whether 9 be installed in place.The push-in of reaction vessel loading assembly 9 could transmit reaction vessel after in place automatically, so that full-automatic chemical Luminescence immunoassay instrument can operate normally.Reaction vessel will not be transmitted if reaction vessel loading assembly 9 is not in place, to guarantee The safety of Full-automatic chemiluminescence immunoassay analysis meter operation.Therefore, reaction vessel loading assembly 9 is detected by detection sensor When push-in whether in place, and be pushed into place after, detection sensor can issue signal in place, so that reaction vessel loading assembly 9 operate normally.Again optionally, also have on reaction vessel loading assembly 9 and inhaled for fixing the fixed of reaction vessel loading assembly 9 Attached component.After reaction vessel loading assembly 9 is installed in place, reaction vessel loading assembly 9 can be fixed on by fixed adsorption element On Full-automatic chemiluminescence immunoassay analysis meter, after reaction vessel loading assembly 9 is pushed by such user, reaction vessel loading assembly 9 can be fixed the reliable and stable fixation of adsorption element, prevent play.Exemplary, fixed adsorption element can be magnet.
Again optionally, the Full-automatic chemiluminescence immunoassay analysis meter of the utility model is carried out using disposable reaction vessel Pattern detection, after the completion of the detection that shines, the reaction vessel needs after use are recovered.Therefore, the full-automation of the utility model Learning luminescence immunoassay instrument further includes the ash can 99 that top has opening, and ash can 99 is set to reaction vessel loading assembly 9 Right side, and be located at the lower section of reaction vessel grabbing assembly 9, reaction vessel grabbing assembly 9 leads to the reaction vessel for excluding waste liquid It crosses opening and is put into ash can 99.It, can also be by ash can 99 from the front side of carrying platform after reaction vessel loading assembly is extracted Extraction, conveniently empties ash can 99.After the completion of reaction vessel carries out luminous detection, the waste liquid in reaction vessel is discharged, then The reaction vessel of rear sky will be used to be transferred in ash can 99, ash can 99 can continuously recycle the reaction vessel after use, keep away Exempt to occupy the position for being incubated for and surveying in optical assembly 2, while being also avoided that the reaction vessel after use is thrown out without care abandoning.Ash can 99 is filled Reaction vessel or after needing to empty reaction vessel in ash can 99, ash can 99 can be immunized from Full-automatic chemiluminescence Analyzer is removed, and ash can 99 is installed on Full-automatic chemiluminescence immunoassay analysis meter again after emptying.
Optionally, have on ash can 99 and judge sensor, for detecting whether ash can 99 loads in place.After emptying Ash can 99 needs to be loaded into Full-automatic chemiluminescence immunoassay analysis meter again, if ash can 99 loads not in place, will affect Using the recycling of rear reaction vessel, while ash can 99 can also exist and Full-automatic chemiluminescence immunoassay analysis meter other structures phase The risk of contact influences Full-automatic chemiluminescence immunoassay analysis meter operation.After setting judges sensor, judge that sensor can be examined Whether in place ash can 99 is surveyed, if sending is believed in place if judgement sensor not in place sounds an alarm or judge in place sensor Number, so that Full-automatic chemiluminescence immunoassay analysis meter operates normally.Again optionally, also there is feedback key on ash can 99, give up Hopper 99 is reloaded after emptying, and pressing feedback key resets the counting of ash can 99.In this way, user empties ash can 99 Afterwards, by feedback key in the counting for emptying ash can 99, when Full-automatic chemiluminescence immunoassay analysis meter is again to ash can 99 It is able to carry out after discarding reaction vessel and counts again, facilitate and reacted in Full-automatic chemiluminescence immunoassay analysis meter monitor passage of waste material case 99 The quantity of container guarantees that Full-automatic chemiluminescence immunoassay analysis meter operates normally.
The Full-automatic chemiluminescence immunoassay analysis meter of the utility model is existed reaction vessel by reaction vessel grabbing assembly 5 Reaction vessel loading assembly 9 mixes seat, is incubated for survey between optical assembly 2, Magneto separate cleaning assembly 4 and ash can 99 and shift.Specifically , reaction vessel grabbing assembly 5 has vertical movement mechanism, horizontal cross movement mechanism and horizontal depth movement mechanism, reaction Container grabbing assembly 5 realizes three-dimensional space by vertical movement mechanism, horizontal cross movement mechanism and horizontal depth movement mechanism Any position movement, realizes any position crawl and the release reaction vessel of three-dimensional space, and then realizes the transfer of reaction vessel. Moreover, reaction vessel grabbing assembly 5, which also has, grabs a glass hand, horizontal cross movement mechanism is set in vertical movement mechanism, horizontal Depth movement mechanism is set on horizontal cross movement mechanism, is grabbed a glass hand and is set on horizontal depth movement mechanism.Vertical movement Mechanism, horizontal cross movement mechanism and horizontal depth movement mechanism, which are moved respectively and be able to drive, grabs a glass hands movement, so that grabbing Cup hand can move to any position and carry out crawl and discharge the operation of reaction vessel.It is exemplary, vertical movement mechanism, horizontal cross It include transporting driving motor and synchronous band structure with horizontal depth movement mechanism to movement mechanism, to realize the fortune of respective direction It is dynamic, certainly, synchronous band structure also can be replaced gear & rack structure, chain drive structure or other can be realized linear motion Structure.
After reaction vessel grabbing assembly 5 grabs reaction vessel in reaction vessel loading assembly 9, and reaction vessel is shifted To mixing in seat, separate injection needle 31 is then transferred to mixing seat after drawing sample at the suction sample station of sample reagent loading assembly 1 Reaction vessel in, separate injection needle 31 is then transferred to mixing after drawing reagent at the suction reactant station of sample reagent loading assembly 1 In the reaction vessel of seat, the sample in reaction vessel is uniformly mixed with reagent and forms mixture so that mixing seat.Reaction is held Reaction vessel with mixture is transferred in incubation survey optical assembly 2 by device grabbing assembly 5 from seat is mixed again, is incubated for and is surveyed light group After part 2 is incubated for the mixture in reaction vessel, so that the mixture in reaction vessel forms determinand and impurity.So Afterwards, the reaction vessel with determinand and impurity is surveyed in optical assembly 2 from incubation and is transferred to Magneto separate by reaction vessel grabbing assembly 5 In cleaning assembly 4, the impurity in reaction vessel is cleaned by removal by Magneto separate cleaning assembly 4.Reaction vessel can be in Magneto separate Substrate is added at cleaning assembly 4, after the completion of addition, reaction vessel grabbing assembly 5 is by reaction vessel from 4 turns of Magneto separate cleaning assembly It moves on in incubation survey optical assembly 2 and is incubated for, the reaction vessel after incubation carries out the detection that shines again, after the completion of detection, will react After waste liquid in container excludes, shifted by reaction vessel grabbing assembly 5 by the reaction vessel surveyed after detecting in optical assembly 2 is incubated for Into ash can 99.
Referring to Fig. 1 and Figure 10, as an embodiment, Full-automatic chemiluminescence immunoassay analysis meter further includes mixing group Part 6 mixes component 6 and is used to mix the liquid in reaction vessel.Component 6 is mixed for mixing the sample in reaction vessel with reagent Mixture is closed uniformly and is formed, so that sample is sufficiently reacted in being incubated for survey optical assembly 2 with reagent, to guarantee pattern detection As a result accuracy.It mixes component 6 to be located between incubation survey optical assembly 2 and sample reagent loading assembly 1, reaction vessel crawl group Empty reaction vessel is transferred to from reaction vessel loading assembly 9 and mixes in component 6 by part 5, and separate injection needle 31 is respectively by sample reagent Sample and agent transfer in loading assembly 1 forms mixing after mixing component 6 and mixing into the reaction vessel for mixing component 6 Object, reaction vessel grabbing assembly 5 again by reaction vessel be transferred to incubation survey optical assembly 2 in be incubated for and formed determinand with it is miscellaneous Matter, after incubation, reaction vessel grabbing assembly 5 by reaction vessel from be incubated for survey optical assembly 2 be transferred in Magneto separate cleaning assembly 4 into Row separation cleaning, after cleaning, reaction vessel is transferred to incubation from Magneto separate cleaning assembly 4 and surveys light by reaction vessel grabbing assembly 5 Component 2 carries out the detection that shines.Optionally, after adding substrate in reaction vessel, mix component 6 can also by reaction vessel to It surveys object to be uniformly mixed with substrate, to increase the luminous value of determinand.At this point, being injected into the reaction vessel after Magneto separate cleans Reaction vessel is transferred to from Magneto separate cleaning assembly 4 by reaction vessel grabbing assembly 5 and is mixed in component 6 by substrate, by mixed Determinand in reaction vessel is uniformly mixed by even component 6 with substrate, and then reaction vessel grabbing assembly 5 is by reaction vessel from mixed It is transferred to incubation in even component 6 and surveys optical assembly 2, is incubated for after survey optical assembly 2 carries out incubation operation and carries out the detection that shines.
Mixing component 6 includes mixing seat, mixing mechanism 64 and mixing driving mechanism 61.The driving of driving mechanism 61 is mixed to mix Mechanism 64 moves, to mix sample and reagent on seat in reaction vessel.Mixing driving mechanism 61 is to mix component 6 to realize The power source of operation is mixed, mixing mechanism 64 is used to transmit the movement for mixing driving mechanism 61.In the present embodiment, mixing seat is A part of component 6 is mixed, driving mechanism 61 is mixed and mixing mechanism 64 is driven to move, and then mixing mechanism 64 drives and mixes seat fortune It is dynamic, the mixing of sample and reagent and the mixing of determinand and substrate in reaction vessel are realized by mixing seat.
Exemplary, mixing driving mechanism 61 includes synchronous band structure and motor, and synchronous belt structure driven connects the defeated of motor Shaft and mixing mechanism 64 to drive mixing mechanism 64 to move, and then are driven by mixing mechanism 64.Certainly, synchronous band structure Also chain drive structure or gear transmission structure etc. be can be replaced.Mixing mechanism 64 includes crankshaft, limiting component and guiding parts, Synchronous band structure is connect with crankshaft, and the top of crankshaft is connect with mixing seat and guiding parts, and limiting component has limiting slot, guiding Component is movably located in limiting slot.When crankshaft does eccentric motion synchronous belt structure motion, it is able to drive crankshaft and does eccentric turn It is dynamic, and then crankshaft drives mixing seat and guiding parts to do eccentric rotary, since guiding parts is located in limiting slot, limiting slot can The rotational motion of restricted guidance component, so that guiding parts does the reciprocating motion along limiting slot direction, in this way, mixing seat The reciprocating motion along limiting slot direction can only be done, can rapidly be mixed the substance in the reaction vessel for mixing seat in this way. Exemplary, guiding parts is directive wheel.
Optionally, mixing component 6 has further included the mixing platform for carrying supporting role, mixes each components of component 6 It is respectively provided with and mixes on platform, mix platform and be fixed on carrying platform.Synchronous band structure and mixing seat, which are located at, mixes the two of platform Side, crankshaft pass through mixing platform and connect with seat is mixed.Mixing component 6 further includes bearing block, and crankshaft is set to mixed by bearing block On even platform, avoids crankshaft from interfering guarantee with mixing platform by bearing block and run smoothly.
In the other embodiments of the utility model, mixing seat can also be static support construction, mix driving mechanism 61 are independently arranged with mixing mechanism 64 with seat is mixed, and mixing mechanism 64 can be stirring rod at this time, mix driving mechanism 61 and drive Stirring rod carries out mixing operation.Stirring rod can be extend into reaction vessel, to the sample and reagent or determinand in reaction vessel It is stirred with substrate, so that the material mixing in reaction vessel is uniform;After the completion of mixing, stirring rod is moved from reaction vessel Out.In the other embodiments of the utility model, if sample and reagent are without mixing operation, mixing portion can be supported merely Reaction vessel, as long as can be realized the support and transfer of reaction vessel.Mixing seat is stationary support structure or its simple branch When support acts on, mixing seat can be bracket.
Further, mixing has sample mixing portion 62 and substrate mixing portion 63 on seat, sample mixing portion 62 is for carrying At least one reaction vessel with sample and reagent, and for mixing sample and reagent in reaction vessel, substrate mixing portion 63 For carrying the reaction vessel with substrate, and for mixing determinand and substrate in reaction vessel.Seat is mixed to be able to drive Sample mixing portion 62 and substrate mixing portion 63 carry out mixing operation simultaneously.Specifically, the quantity of mixing mechanism 64 is two, mix Driving mechanism 61 drives sample mixing portion 62 and substrate mixing portion 63 to carry out mixing behaviour simultaneously respectively by two mixing mechanisms 64 Make.That is, sample mixing portion 62 and substrate mixing portion 63 can be driven to move simultaneously by a mixing driving mechanism 61, The quantity that power source can be reduced in this way, reduces the cost, while can also reduce the volume for mixing component 6.
Two mixing mechanisms 64 respectively correspond sample mixing portion 62 and substrate mixing portion 63, by crankshaft, guiding parts and The cooperation of limiting component is so that sample mixing portion 62 moves reciprocatingly respectively with substrate mixing portion 63, in realization sample mixing portion 62 The mixing of sample and reagent in reaction vessel, and realize in substrate mixing portion 63 the mixed of determinand and sample in reaction vessel It is even.Moreover, there are at least two samples to mix position in sample mixing portion 62, at least two reaction vessels can be carried simultaneously in this way, In addition substrate mixing portion 63 carries a reaction vessel, can carry out mixing operation at least three reaction vessels simultaneously, save Mixing time improves complete machine operational efficiency.In the present embodiment, there are two samples to mix position, and two for the tool of sample mixing portion 63 A sample mixes position and inhales sample station and multiple suction reagent wells 1231 collinearly.Certainly, in other embodiment party of the utility model In formula, there is at least one substrate to mix position in substrate mixing portion 63.
Referring to Fig. 1 and Figure 19, as an embodiment, Full-automatic chemiluminescence immunoassay analysis meter further includes main control Component 77 and power supply module 10, power supply module 10 are electrically connected with main control component 77, main control component 77 respectively with sample reagent Loading assembly 1, dispensing component 3 are incubated for and survey optical assembly 2, mix component 6, Magneto separate cleaning assembly 4, reaction vessel grabbing assembly 5, reaction vessel loading assembly 9, ash can 99 and the electrical connection of fluid path component 8, main control component 77 and power supply module 10, which are located at, to be held Below carrying platform.Integrated software control system in main control component 77, realizes Full-automatic chemiluminescence by software control system The all parts of immunity analysis instrument, which cooperate, to be moved, and the operational efficiency of Full-automatic chemiluminescence immunoassay analysis meter is improved.Master control The lower section that component 77 processed is set to carrying platform can reduce the volume of each components, greatly reduce and occupy on the carrying platform Space be conducive to Full-automatic chemiluminescence immunoassay analysis meter so that Full-automatic chemiluminescence immunoassay analysis meter is compact-sized Trend toward miniaturization.Moreover, main control component 77 integrates the control of each components, operation is maintained easily, moreover it is possible to Reduce the cost and failure rate of machine.
Referring to Fig. 1 to Fig. 3, as an embodiment, sample reagent loading assembly 1 includes the sample for sample loading This loader mechanism 11 and load reagents mechanism 12 for loaded reagent, sample loader mechanism 11 are sheathed on load reagents mechanism 12 outside, and sample loader mechanism 11 and load reagents mechanism 12 rotate independently of each other.Sample loader mechanism 11 can store Sample to be detected, load reagents mechanism 12 store various reagents required when pattern detection.Also, sample reagent loader mechanism 12 are sheathed on the outside of load reagents mechanism 12, can reduce the volume of sample reagent loading assembly 1 in this way, are conducive to reduce complete machine Volume.In the present embodiment, the setting in disk form of load reagents mechanism 12, correspondingly, the shape of sample loader mechanism 11 is ring Shape, and sample loader mechanism 11 is arranged concentrically with load reagents mechanism 12, so that 1 occupied space of sample reagent loading assembly is most It is small, meanwhile, sample loader mechanism 11 is not contacted with load reagents mechanism 12, guarantee that movement between the two will not interfere, Guarantee runs smoothly.It is located on sample loader mechanism 11 moreover, inhaling sample station, inhales reactant station and be located at load reagents mechanism 12 On, and inhaling reactant station and inhaling sample station is position fixed on carrying platform.Sample loader mechanism 11 drives sample thereon The rotation of this container, so that the sample container of sample to be detected, which is in, inhales sample station, sample work can inhaled by dispensing component 3 at this time It draws sample and is transferred in the reaction vessel for mixing seat in position.Load reagents mechanism 12 drives reagent container rotation thereon, makes The reagent container for obtaining reagent to be drawn, which is in, inhales reactant station, and reactant station absorption reagent can inhaled simultaneously by dispensing component 3 at this time It is transferred in the reaction vessel for mixing seat.
Specifically, sample loader mechanism 11 includes chassis 112, load reagents mechanism 12 includes reagent pot 121, chassis 112 For storing sample, reagent pot 121 is used for storing reagent.Chassis 112 is coaxially set in the outside of reagent pot 121, and chassis 112 rotate independently of each other with reagent pot 121.
Sample loader mechanism 11 further includes that the sample rack 111 of multiple arc-shaped settings and sample load driving structure 113, sample This 111 for carrying the sample container with sample, multiple sample racks 111 are sequentially installed on chassis 112, and sample loads Driving structure 113 drives chassis 112 to rotate, and sample rack 111 is driven to rotate.It can be stored on the sample rack 111 of each arc Multiple sample containers with sample guarantee multiple samples after assembling moreover, the arc radius of each sample rack 111 is consistent Frame 111 forms cyclic structure.Exemplary, sample rack 111 includes upper layer bracket and multiple support columns, and multiple support columns are by upper layer Bracket supports, and has multiple accommodating holes in upper layer bracket, and sample container is installed in accommodating hole.Moreover, multiple support columns Between be spaced setting, and multiple support columns can be directly installed on chassis 112, and certainly, sample rack 111 may also include lower layer's branch Frame, lower floor support are set on chassis 112, and the bottom of support column is installed on lower floor support.It is understood that each sample Frame 111 can be sequentially connected with from beginning to end, can also between there are spacing.Connection can be overlapped between each sample rack 111, can also be led to Cross the connection of the structures such as connector;Furthermore, it is possible to be fixed using the modes such as buckle, connector.In the present embodiment, sample rack 111 Quantity is five.Chassis 111 is annular sample disk.
Exemplary, it includes that sample loads driving motor and gear transmission structure, chassis 112 that sample, which loads driving structure 113, Upper to have teeth portion, gear transmission structure transmission connection sample loads driving motor and chassis 112, and sample loads driving motor driving Synchronous band structure drives chassis 112 to rotate.Certainly, chain drive structure, synchronous band structure etc. also can be used in gear transmission structure Replacement.Sample loads driving structure 113 and drives chassis 112 that sample rack 111 thereon is driven to rotate, so that sample to be detected holds Device, which turns to, inhales sample station, and dispensing component 3 is transferred in the container for mixing seat after drawing sample.It dispenses component 3 and draws sample Afterwards, sample, which loads driving structure 113, can drive chassis 112 that sample rack 111 is driven to rotate again, so that next sample to be detected Container, which turns to, inhales sample station.
Optionally, sample reagent loading assembly 1 further includes storage fixed plate, and storage fixed plate is set on carrying platform, For installing each components of sample loader mechanism 11 and load reagents mechanism 12, with convenience sample loader mechanism 11 and examination The rotate driving of agent loader mechanism 12 avoids interfering.Sample loads driving structure 113 and is set in storage fixed plate, bottom Disk 112 is rotatably fixed to storage fixed plate, and sample loads driving structure 113 and drives the sample rack of the drive of chassis 112 thereon 111 and sample container relative to storage fixed plate rotation.
Again optionally, sample loader mechanism 11 further includes pulley bearings, and pulley bearings have slideway, and sliding bearing is lain against It stores in fixed plate, and the edge on chassis 112 is located in the slideway of pulley bearings.Sample loads driving structure 113 and drives chassis When 112 rotation, pulley bearings can support chassis 112 so that 112 smooth rotation of chassis, meanwhile, slideway is also able to guide chassis 112 rotations.It is exemplary, the quantity of pulley bearings be it is multiple, multiple pulley bearings are uniformly distributed in the side on chassis 112, guarantee 112 uniform force of chassis and support is reliable.In the present embodiment, the quantity of pulley bearings is four.
Load reagents mechanism 12 further includes reagent disc 122 and reagent storage driving structure 126, and reagent disc 122 is contained in examination In agent pot 121, reagent disc 122 is used to store the reagent container with reagent, and reagent storage driving structure 126 drives reagent disc 122 rotate relative to sample loader mechanism 11.Reagent pot 121 is fixed in storage fixed plate, reagent storage driving structure 126 It is set in storage fixed plate, and protrudes into reagent pot 121 and connect with reagent disc 122, to drive reagent disc 122 in reagent pot It is rotated in 121.Reagent pot 121 can play cold storage function, can refrigerate the reagent on reagent disc 122, realize the low temperature of reagent It saves;Moreover, at complete machine in the shutdown state, reagent pot 121 can support reagent to continue refrigeration to lower temperature, to try Agent is stayed overnight in machine.
Reagent storage driving structure 126 includes that reagent storage driving motor, synchronous band structure and shaft, shaft extend into examination In agent pot 121, synchronous belt structure driven connection reagent storage driving motor and shaft, reagent disc 122 are installed in shaft.Examination Agent storage driving motor passes through synchronous band structure drive shaft rotation, and then shaft drives reagent disc 122 to rotate, so that reagent disc Reagent container to be drawn is transferred to suction reactant station in 122, and dispensing component 3 draws reagent and is transferred to the reaction for mixing seat In container;After dispensing the absorption reagent of component 3, reagent storage driving structure 126 can drive reagent disc 122 to rotate again, so that Next reagent container to be detected turns to suction reactant station.Certainly, synchronous band structure can use gear transmission structure, chain conveyer Structure etc. replacement.
Optionally, reagent storage driving structure 126 further includes rolling bearing, and rolling bearing is set on reagent pot 121, and The outer ring of rolling bearing is connect with reagent pot 121, and the inner ring of rolling bearing is connect with shaft, and reagent storage driving motor passes through same The rotation of band structure drive shaft is walked, so that shaft drives the center rotating of 122 position reagent pot 121 of reagent disc.Shaft is by turning Dynamic bearing is fixed on reagent pot 121, while rolling bearing is also avoided that between the shaft of rotation and static reagent pot 121 and deposits Interfering, is guaranteeing that stability of rotation is reliable.
Further, load reagents mechanism 12 further includes reagent pot cover 123, and reagent pot cover 123 is covered on reagent pot 121 On.Reagent pot cover 123 can be avoided the loss of the cooling capacity in reagent pot 121, guarantee refrigeration effect, save cost.Moreover, reagent pot Lid 123 has multiple suction reagent wells 1231, and multiple reagent wells 1231 of inhaling are arranged along the radial direction of reagent disc 122, and are located at one On straight line, separate injection needle 31 can extend into any suction reagent wells 1231 and draw reagent.Multiple suction reagent wells 1231 can make point Infuse the reagent in the absorption different location reagent container of needle 31.The quantity of reagent container on reagent disc 122 can be increased in this way.It can be with Understand, multilayer reagent container is arranged layer by layer, same in the radial direction also with multiple reagent containers in reagent disc 122.And And the reagent container of same radial direction respectively corresponds multiple suction reagent wells 1231, in this way, separate injection needle 31 can be inhaled without rotation The reagent for taking any position facilitates selection, saves the time of transfering reagent.It should be noted that each inhales reagent wells 1231 As one suction reactant station, separate injection needle 31 can draw reagent in any suction reactant station.
In embodiment, tool is there are four reagent wells 1231 are inhaled on reagent pot cover 123, and four suction reagent wells 1231 are the same as always On line, and four are inhaled reagent wells 1231 and also extended along the radial direction of reagent disc 122.When transfering reagent, reagent storage driving knot Structure 126 drives reagent disc 122 that reaction vessel thereon is driven to rotate, so that the reaction vessel of reagent to be drawn turns to suction examination At agent hole 1231, four reagent containers respectively correspond four suction reagent wells 1231, and it is corresponding that separate injection needle 31 can choose required reagent Suction reagent wells 1231 draw reagent.Moreover, the setting for inhaling reagent wells 1231 is also avoided that reagent pot cover 123 is open excessive cause Cooling capacity in reagent pot 121 is excessive.
Further, load reagents mechanism 12 further includes switch cover 124, is had on reagent pot cover 123 for placing or taking Reagent container takes opening out, switchably the taking in opening positioned at reagent pot cover 123 of switch cover 124.Switch cover 124 is For a tegillum on reagent pot cover 123, when the reagent in reagent container a certain on reagent disc 122 requires supplementation with, opening is opened Lid 124 is closed, takes out reagent container by taking opening, after having supplemented reagent, then opening is taken and reagent container is placed in examination On agent disk 122.Operator can be facilitated to use in this way, while also be avoided that in reagent pot 121 that cooling capacity is lost.Optionally, it opens The one end for closing lid 124 is rotatably installed on reagent pot cover 123, and the other end of switch cover 124 can be 123 turns around reagent pot cover It is dynamic, opening is taken to open or close.Certainly, in the other embodiments of the utility model, switch cover 124 can also be moved integrally It removes, it is fixed by positioning pin etc..
Referring to Fig. 1 and Fig. 9, as an embodiment, dispensing component 3 further includes dispensing punch block and dispensing driving portion. Dispensing punch block is located at the rear side above sample reagent loading assembly 1, and dispensing driving portion is set on dispensing punch block, divides for driving Needle 31 is infused to move.Specifically, dispensing driving portion includes horicontal motion mechanism 33 and vertical motion mechanism 32, vertical motion mechanism 32 It is set on horicontal motion mechanism 33, separate injection needle 31 is set in vertical motion mechanism 32, vertical motion mechanism 32 and horizontal fortune Motivation structure 33 moves, and makes separate injection needle 31 in sample reagent loading assembly 1 and mixes transfer sample and reagent between seat.Vertical motion Mechanism 32 is able to drive separate injection needle 31 and moves up and down, and realizes the absorption or discharge of sample and reagent.33 energy of horicontal motion mechanism Enough separate injection needle 31 is driven to move in the horizontal direction, realizes the transfer of sample and reagent.When vertical motion mechanism 32 drives separate injection needle When 31 decline, separate injection needle 31 draws sample or reagent, and after the completion of absorption, vertical motion mechanism 32 drives separate injection needle 31 to reset;With Horicontal motion mechanism 33 drives separate injection needle 31 to move in the horizontal direction afterwards, mixes at seat so that separate injection needle 31 moves to, vertical to transport Motivation structure 32 drives separate injection needle 31 to decline, and sample or reagent is discharged in separate injection needle 31, and after the completion of discharge, vertical motion mechanism 32 is driven Separate injection needle 31 resets;Subsequent horicontal motion mechanism 33 drives separate injection needle 31 to move in the horizontal direction, so that separate injection needle 31 returns to sample At this load reagents component 1, continue to draw sample or reagent operation.
Dispensing punch block includes dispensing fixed plate and dispensing horizontal mounting plate, and dispensing fixed plate is used to support dispensing component 3 Other components.Horicontal motion mechanism 33 includes dispensing horizontal drive motor and dispensing horizontal conveyor structure.Dispense horizontal drive Motor and dispensing horizontal conveyor structure are mounted on dispensing horizontal mounting plate, and dispensing horizontal mounting plate is installed on dispensing level biography In dynamic structure, dispensing horizontal drive motor driven dispenses horizontal conveyor structure motion, so that dispensing horizontal conveyor structure drive point Note horizontal mounting plate moves horizontally.Vertical motion mechanism 32 includes dispensing vertical driving motor and the vertical drive mechanism of dispensing, It dispenses vertical driving motor and dispenses vertical drive mechanism and be all set on dispensing horizontal mounting plate, dispensing horizontal mounting plate movement It is able to drive the vertical driving motor of dispensing and the vertical drive mechanism movement of dispensing.Dispensing punch block further includes dispensing vertical fixed plate, It dispenses vertical fixed plate to be installed on the vertical drive mechanism of dispensing, separate injection needle 31 is installed in the vertical fixed plate of dispensing, and dispensing is perpendicular Straight driving motor drives the vertical drive mechanism movement of dispensing to be able to drive the vertical fixed plate of dispensing and moves up and down, and then drives and divide Note needle 31 moves up and down;Moreover, dispensing horizontal drive motor drives dispensing vertical motion machine by dispensing horizontal conveyor structure Structure 32 and the vertical fixed plate of dispensing move horizontally, and then dispensing is driven to move horizontally.
Exemplary, dispensing horizontal conveyor structure and the vertical drive mechanism of dispensing can be that synchronous belt structure dispenses water certainly Flat drive mechanism and dispense vertical drive mechanism can also for chain drive structure, gear & rack structure or other can be realized straight line The structure of movement.Separate injection needle 31 is controlled by the cooperation of horicontal motion mechanism 33 and vertical motion mechanism 32 to move horizontally and rise Drop movement, realizes the suction and transfer of sample and reagent.Moreover, vertical motion mechanism 32 drives separate injection needle 31 when drawing reagent Decline, separate injection needle 31 is protruded into the reagent container in reagent pot 121 by inhaling reagent wells 1231 at this time, and draws reagent, is drawn After the completion, vertical motion mechanism 32 drives separate injection needle 31 to rise, at this point, separate injection needle 31 leaves reagent pot by inhaling reagent wells 1231 121.When drawing sample, separate injection needle 31 is inhaling the progress of sample station, and operating procedure is identical with reagent is inhaled, herein not one by one It repeats.
Further, dispensing component 3 further includes the separate injection needle swab 34 connecting with horicontal motion mechanism 33.Separate injection needle swab 34 are sheathed on separate injection needle 31, and can move horizontally with separate injection needle 31, and separate injection needle 31 is done relative to separate injection needle swab 34 When elevating movement, separate injection needle swab can be to the outer wall washing of separate injection needle.Specifically, horicontal motion mechanism 33 also drives separate injection needle Swab 34 moves, when vertical motion mechanism 32 drives separate injection needle 31 to go up and down, outer wall washing of the separate injection needle swab 34 to separate injection needle 31. That is, dispensing component 3 carries cleaning function module, and the cleaning function module can do together level with separate injection needle 31 Movement, when separate injection needle 31 do vertical motion or it is static when, which can clean separate injection needle 31.Such energy The frequently access service sink of separate injection needle 31 is enough avoided, the working efficiency of separate injection needle 31 is improved.
It is understood that requiring to be cleaned, to avoid sample after the every absorption of separate injection needle 31 or discharge sample and reagent The outer wall that this or reagent remain in separate injection needle 31 leads to cross contamination and influences the accuracy of pattern detection.It is exemplary, separate injection needle There is dispensing cleaning center hole, dispensing cleaning import and dispensing washing outlet on swab 34.Separate injection needle 31 passes through in dispensing cleaning Heart hole passes through separate injection needle swab 34, and when 31 elevating movement of separate injection needle, and separate injection needle 31 can be by moving along dispensing cleaning center hole. Moreover, separate injection needle 31, during elevating movement, separate injection needle 31 can be cleaned by the cleaning solution in separate injection needle swab 34, tool Body, cleaning solution flows into separate injection needle swab 34 by dispensing cleaning import, and from dispensing washing outlet outflow, cleaning solution is flowing It can be in contact in the process with the outer wall of separate injection needle 31, surface, that is, outer wall of separate injection needle 31 is cleaned in realization.It is clear from dispensing The cleaning waste liquid for washing out mouth outflow can be discharged in waste liquid barrel, and waste liquid barrel is located at the lower section of carrying platform.It should be noted that The conveying and discharge of cleaning solution realize that this point is described in detail later by fluid path component 8 in separate injection needle swab 34.
Still further, dispensing component 3 further includes service sink 35, service sink 35, which is set to, to be mixed on platform, service sink 35 For picking up the cleaning waste liquid after 31 inner wall washing of separate injection needle.Service sink 35 is a fixed cleaning module, when separate injection needle 31 After having added sample and reagent to the reaction vessel mixed in component 6, it is also necessary to also clean, keep away to the inner wall of separate injection needle 31 Exempt from sample or reagent remains in the inner wall of separate injection needle 31 leads to cross contamination and influence the accuracy of pattern detection.
Separate injection needle 31 is after mixing the sample mixing portion 62 at seat and having added sample and reagent into reaction vessel, level fortune Motivation structure 33 drives separate injection needle 31 to move at service sink 35, is passed through cleaning solution to the backshank of separate injection needle 31, and pass through separate injection needle 31 are discharged in service sink 35, and are drained into waste liquid barrel by service sink 35.Moreover, separate injection needle 31 will cleaning after cleaning inner wall After waste liquid is discharged to service sink 35, cleaning waste liquid can generate vortex in service sink 35, and then being vortexed also can be to separate injection needle 31 Outer wall cleaned.
Certainly, in the other embodiments of the utility model, service sink 35, which may be alternatively located at, mixes seat and sample reagent dress It carries on the carrying platform between component 1.Moreover, sample mixing portion 62 and service sink 35 close on setting, also, service sink 35 In sample mixing portion 62 and inhale between sample station.After separate injection needle 31 has added sample or reagent to sample mixing portion 62, dispensing Needle 31, which needs to return, draws sample or reagent at sample reagent loading assembly 1, service sink 35 is located at the path of the return of separate injection needle 31 On, separate injection needle 31 is first moved at service sink 35 when returning and is cleaned, and is then further continued for coming back for inhaling sample or is inhaled reagent Operation.In such manner, it is possible to reduce the motion path of separate injection needle 31, the efficiency that separate injection needle 31 shifts sample and reagent is improved.
Certainly, in the other embodiments of the utility model, cleaning solution, vertical motion can also be injected into service sink 35 Mechanism 32 controls separate injection needle 31 and declines, and to clean the outer wall of separate injection needle 31, after the completion of cleaning, vertical motion mechanism 32, which drives, to be divided Needle 31 is infused to rise, meanwhile, the cleaning waste liquid in service sink 35 is discharged.It is understood that realizing cleaning by fluid path component 8 The conveying of liquid and the discharge for cleaning waste liquid, this point are described in detail later.
Preferably, it is conllinear to inhale sample station, multiple suction reagent wells 1231, sample mixing portion 62 and service sink 35.Namely It says, the suction sample station of sample loader mechanism 11, multiple suction reagent wells 1231 of load reagents mechanism 12, the sample of mixing seat are mixed Even portion 62 and second dispenses wiper mechanism 35 point-blank, and the horizontal movement of the straight line and separate injection needle 31 and vertical fortune Dynamic place plane is overlapped.When horicontal motion mechanism 33 drives separate injection needle 31 to move horizontally in this way, separate injection needle 31 can be distinguished By inhaling sample station, multiple suction reagent wells 1231, sample mixing portion 62 and service sink 35, realize that passing through a separate injection needle 31 is Sample or reagent can be drawn simultaneously and accurately be filled into sample mixing portion 62 and cleaned, so that Full-automatic chemiluminescence Compact-sized, the reduction machine volume of immunity analysis instrument, while can also lowering apparatus cost.
Referring to Fig. 1, Fig. 9, Figure 16 and Figure 19, as an embodiment, fluid path component 8 includes dispensing liquid channel system 81.Liquid channel system 81 is dispensed for realizing 31 sample of separate injection needle and reagent suction and the cleaning of separate injection needle 31.Dispense fluid path system System 81 is connect with separate injection needle 31, can be controlled separate injection needle 31 and be drawn sample or reagent, while can also be by the sample in separate injection needle 31 Or reagent discharge.Specifically, the dispensing liquid channel system 81 of Full-automatic chemiluminescence immunoassay analysis meter further includes the injection of the first dispensing Device SR1, the first divide syringe SR1 are located at the rear side of carrying platform (specifically, being located at the right side region on rear side of carrying platform Domain), the first divide syringe SR1 passes through pipeline respectively and is connected to separate injection needle 31 and separate injection needle swab 34, and cleaning solution is supplied to It is supplied to separate injection needle 31 and separate injection needle swab 34.
Specifically, dispensing liquid channel system 81 further includes dispensing suction pipeline 811 and the first dispensing control valve V811.First point Note control valve V811 is connected between the first divide syringe SR1 and dispensing suction pipeline 811, for controlling dispensing suction pipeline 811 on-off.Dispensing suction pipeline 811 is also connected with the separate injection needle 31 of dispensing component 3.First dispensing control valve V811 connection dispensing Suction pipeline 811 and when the first divide syringe SR1, dispenses 3 suction sample of component and reagent.It is understood that this is practical Control valve in novel can refer to two-position three-way valve, can also refer to multidigit multiple-way valve, can also can be realized on-off for other Valve such as threeway cooperation switch valve etc..
One end of first dispensing control valve V811 is connect with the first divide syringe SR1, the first dispensing control valve V811's The other end is connect with one end of dispensing suction pipeline 811, and the backshank of the other end and separate injection needle 31 that dispense suction pipeline 811 connects It connects.When first dispensing control valve V811 control dispensing suction pipeline 811 is access, the first dispensing control valve V811 is connected to first point Syringe SR1 and dispensing suction pipeline 811 are infused, sample or reagent are drawn by separate injection needle 31 and is stored in the first divide syringe In SR1;After the completion of absorption, horicontal motion mechanism 33 and vertical motion mechanism 32 drive separate injection needle 31 to move to mixing component 6 At sample mixing portion 62, the sample of absorption and reagent are passed through separate injection needle through dispensing suction pipeline 811 by the first divide syringe SR1 31 are discharged in reaction vessel;When cleaning 31 inner wall of separate injection needle, the first divide syringe SR1 will be clear through dispensing suction pipeline 811 Washing lotion is transported in separate injection needle 31, is cleaned with the inner wall to separate injection needle 31, after the completion of cleaning, by the liquid in separate injection needle 31 Discharge.
Moreover, dispensing liquid channel system 81 is also connect with separate injection needle swab 34, to provide cleaning solution to separate injection needle swab 34.This Sample, which can be realized, dispenses suction and the separate injection needle 31 that liquid channel system 81 had both realized sample and reagent by a power source drive The cleaning of inner wall, and can be realized the cleaning of 31 outer wall of separate injection needle, to save an injector assembly compared to traditional design. Specifically, dispensing liquid channel system 81 further includes the first dispensing detergent line 812, the first dispensing detergent line 812 connects first point Infuse control valve V811 and separate injection needle swab 34.First dispensing control valve V811 connection first dispenses detergent line 812 and first point While infusing syringe SR1, the first divide syringe SR1 of shutdown and dispensing suction pipeline 811, for cleaning the outer of separate injection needle 31 Wall.
It is understood that the first divide syringe of one end connection SR1 of the first dispensing control valve V811, the first dispensing control The another both ends of valve V811 processed are separately connected dispensing suction pipeline 811 and the first dispensing detergent line 812, the first dispensing detergent line 812 other end is connect with the cleaning import of the dispensing of separate injection needle swab 34.First dispensing control valve V811 connection the first dispensing note While emitter SR1 is with dispensing suction pipeline 811, the dispensing detergent line 812 of the first divide syringe SR1 and first is turned off, this When, the first divide syringe SR1 draws sample or reagent by separate injection needle 31 through dispensing suction pipeline 811, and is stored in first In divide syringe SR1;After the completion of absorption, it is mixed that horicontal motion mechanism 33 and vertical motion mechanism 32 drive separate injection needle 31 to move to At the sample mixing portion 62 of even component 6, the first divide syringe SR1 is by the sample of absorption and reagent through dispensing suction pipeline 811 It is discharged in reaction vessel by separate injection needle 31;When cleaning 31 inner wall of separate injection needle, the first divide syringe SR1 is through dispensing suction pipe Cleaning solution is transported in separate injection needle 31 by road 811, is cleaned with the inner wall to separate injection needle 31, after the completion of cleaning, by separate injection needle Liquid discharge in 31.When cleaning 31 outer wall of separate injection needle, the first dispensing control valve V811 turns off the first divide syringe SR1 and divides While infusing suction pipeline 811, it is connected to the dispensing detergent line 812 of the first divide syringe SR1 and first, at this point, the first dispensing Cleaning solution is transported to dispensing from the cleaning import of the dispensing of separate injection needle swab 34 through the first dispensing detergent line 812 by syringe SR1 In needle swab 34, after cleaning the outer wall of separate injection needle 31, then by the dispensing washing outlet discharge of separate injection needle swab 34.
First divide syringe SR1 is the power source for dispensing liquid channel system 81 and drawing sample or reagent and conveying cleaning solution, Separate injection needle 31 is controlled by the first divide syringe SR1 and divides suction sample and reagent, moreover it is possible to control suction cleaning solution.First dispensing Syringe SR1 dispenses suction operation and the cleaning operation that control valve V811 realizes separate injection needle 31 by a valve i.e. first, this Sample had both been able to achieve 31 suction sample of separate injection needle and reagent and had cleaned the function of 31 inner wall of separate injection needle, while being also able to achieve to dispensing The outer wall of needle 31 is cleaned.
Further, dispensing liquid channel system 81 can also draw cleaning solution, without being drawn by separate injection needle 31, improve and divide The utilization rate of needle 31 is infused, but also conveniently the inside and outside wall of separate injection needle 31 is cleaned, separate injection needle 31 is improved and draws sample and examination The frequency of agent, and then improve complete machine operational efficiency.Certainly, in the other embodiments of the utility model, dispensing can also be used The mode that needle 31 draws cleaning solution is cleaned, and 31 inner wall of separate injection needle can be cleaned by drawing cleaning solution such as separate injection needle 31, will be cleaned Liquid, which is transferred in service sink 35, can clean 31 outer wall of separate injection needle, can be incited somebody to action by the switch control of the first dispensing control valve V811 Cleaning solution enters separate injection needle swab through dispensing suction pipeline 811, the first divide syringe SR1, the first dispensing detergent line 812 In 34.
Specifically, dispensing liquid channel system 81 further includes the dispensing detergent line 813 of the second dispensing control valve V812 and second.The Two dispensing control valve V812 connection the first divide syringe SR1 and the first dispensing control valve V811, the second dispensing control valve V812 Connection the second dispensing detergent line 813, the second dispensing detergent line 813 are also connected to the soda liquor container with cleaning solution.Second While dispensing dispensing detergent line 813 the first divide syringe SR1 of connection and second control valve V812, shutdown the first dispensing note The dispensing control valve V811 of emitter SR1 and first, for cleaning separate injection needle 31.Second dispensing control valve V812 shutdown the first dispensing note While dispensing detergent line 813 emitter SR1 and second, it is connected to the dispensing control valve of the first divide syringe SR1 and first The cleaning solution of absorption can be transported in separate injection needle 31 or separate injection needle swab 34 by V811.
One end of second dispensing control valve V812 is connect with the first divide syringe SR1, the second dispensing control valve V812's Another both ends are connect with one end of one end of the second dispensing detergent line 813 and the first dispensing control valve V811 respectively, the second dispensing One end of detergent line 813 is extend into soda liquor container.The first dispensing another both ends control valve V811 then connect point above Infuse suction pipeline 811 and the first dispensing detergent line 812.
When cleaning, dispensing liquid channel system 81 first draws cleaning solution, and cleaning solution is then transported to separate injection needle 31 or dispensing again In needle swab 34.Specifically, the second dispensing control valve V812 is connected to the dispensing detergent line of the first divide syringe SR1 and second While 813, the dispensing control valve V811 of the first divide syringe SR1 and first is turned off, at this point, the first divide syringe SR1 is logical The cleaning solution in the second dispensing absorption soda liquor container of detergent line 813 is crossed, and is stored in the first divide syringe SR1;So Afterwards, while the second dispensing control valve V812 turns off the first divide syringe SR1 with the second dispensing detergent line 813, it is connected to the The dispensing control valve V811 of one divide syringe SR1 and first, at this point, if the outer wall of cleaning separate injection needle 31, the first dispensing control Valve V811 is connected to the first divide syringe SR1 and separate injection needle swab 34, and cleaning solution is transported to dispensing by the first divide syringe SR1 In needle swab 34;If cleaning the inner wall of separate injection needle 31, the first dispensing control valve V811 is connected to the first divide syringe SR1 and divides Suction pipeline 811 is infused, cleaning solution is transported in separate injection needle 31 by the first divide syringe SR1.
Moreover, the dispensing liquid channel system 81 of Full-automatic chemiluminescence immunoassay analysis meter further includes the second divide syringe SR6, Second divide syringe SR6 is connected between the first divide syringe SR1 and separate injection needle 31, and is located at the rear side of carrying platform (specifically, being located at the right area on rear side of carrying platform), make 31 suction sample of separate injection needle or reagent.Second divide syringe The capacity of SR6 is less than the first divide syringe SR1, and the second divide syringe SR6 is fixed-quantity injector, can be realized quantitative Sample and/or reagent are drawn, it is reliable to guarantee that sample and reagent are drawn.Moreover, the cleaning solution energy that the first divide syringe SR1 is drawn It is enough to be transported in separate injection needle 31 through the second divide syringe SR6, it is also able to achieve during conveying to the second divide syringe SR6 is cleaned, and cross contamination is further avoided.
Still further, dispensing liquid channel system 81 further includes the first dispensing removal waste fluid component, the first dispensing removal waste fluid component It is connect with separate injection needle swab 34, the cleaning waste liquid for being discharged in separate injection needle swab 34.Specifically, the first dispensing removal waste fluid component One end connect with the dispensing washing outlet of separate injection needle swab 34, it is flat that the other end of the first dispensing removal waste fluid component extend into carrying In waste liquid barrel below platform.First divide syringe SR1 will be transported to through the first dispensing detergent line 812 through dispensing cleaning import In separate injection needle swab 34, after the completion of cleaning, then is dispensed washing outlet and be transported to the first dispensing removal waste fluid component for waste liquid is cleaned In, and then be transported in waste liquid barrel, realize the discharge of cleaning waste liquid.
Further, dispensing liquid channel system 81 further includes the second dispensing removal waste fluid component, the second dispensing removal waste fluid component It is connect with service sink 35, the cleaning waste liquid for being discharged in service sink 35.Specifically, second dispensing removal waste fluid component one end with The bottom of service sink 35 connects, and the other end of the second dispensing removal waste fluid component is extend into the waste liquid barrel below carrying platform.The Cleaning solution is transported to inside separate injection needle 31 by one divide syringe SR1 through dispensing suction pipeline 811, to clean in separate injection needle 31 After the completion of cleaning, cleaning waste liquid is discharged in service sink 35 for wall, then the bottom in cleaned pond 35 will clean waste liquid and be transported to the It in two dispensing removal waste fluid components, and then is transported in waste liquid barrel, realizes the discharge of cleaning waste liquid.
In the present embodiment, the dispensing liquid channel system 81 of Full-automatic chemiluminescence immunoassay analysis meter further includes the second vacuum pump SR55, the second vacuum pump SR55 are located at the rear side (specifically, the left area for being located at the rear side of carrying platform) of carrying platform, the Two vacuum pump SR55 are connect with separate injection needle swab 34 and service sink 35 respectively, are that cleaning is useless in separate injection needle swab 34 and service sink 35 The discharge of liquid provides power.Specifically, dispensing liquid channel system 81 further includes the dispensing drain of the first dispensing drain line 814, second Pipeline 815 and third dispense control valve V813, and the first dispensing drain line 814 is connected to separate injection needle swab 34, the second dispensing row Liquid pipeline 815 is connected to service sink 35, and the first dispensing drain line 814 and the second dispensing drain line 815 also pass through third point Note control valve V813 is connected to the second vacuum pump SR55, is discharged in waste liquid barrel by the second vacuum pump SR55 by waste liquid is cleaned.Clearly After the completion of washing, cleaning waste liquid can also be discharged in waste liquid barrel by dispensing liquid channel system 81.One end of first dispensing drain line 814 It is connected to the separation cleaning outlet of separate injection needle swab 34, the other end of the first dispensing drain line 814 dispenses control valve by third V813 is connect with the second vacuum pump SR55, and one end of the second dispensing drain line 815 is connect with service sink 35, the second dispensing drain The other end of pipeline 815 dispenses control valve V813 by third and connect with the second vacuum pump SR55.
The cleaning waste liquid of separate injection needle swab 34 can be discharged for first dispensing drain line 814, the second dispensing drain line 815 can be discharged to separate injection needle 31 the cleaning waste liquid discharge in service sink 35.The cleaning waste liquid in separate injection needle swab 34 is discharged When, third dispenses the first dispensing drain line 814 of control valve V813 connection and the second vacuum pump SR55, shutdown the second dispensing drain Pipeline 815 and the second vacuum pump SR55, at this point, the cleaning solution in separate injection needle swab 34 can be discharged by the second vacuum pump SR55 Into waste liquid barrel.When the cleaning waste liquid in separate injection needle 31 is discharged, cleaning waste liquid is first discharged in service sink 35 by separate injection needle 31, so Afterwards, the first dispensing drain line 814 of third dispensing control valve V813 shutdown and the second vacuum pump SR55, connection the second dispensing drain Pipeline 815 and the second vacuum pump SR55, at this point, the cleaning solution in service sink 35 can be discharged to waste liquid by the second vacuum pump SR55 In bucket.
Referring to Fig. 1 and Figure 11, as an embodiment, being incubated for and surveying optical assembly 2 includes sample incubation mechanism 21 and survey Light part 22 surveys light part 22 and is set to incubation block specifically, being incubated for the sample incubation mechanism 21 for surveying optical assembly 2 including being incubated for block 211 211 trailing flank, the reaction vessel after incubation are detected by surveying light part 22.Sample incubation mechanism 21 can be to being transferred to thereon Reaction vessel carries out incubation operation, and the mixture in reaction vessel is sufficiently reacted, and forms determinand and impurity.Survey light Part 22 is used to carry out the determinand in reaction vessel the detection that shines, and removes deimpurity reaction vessel through Magneto separate cleaning assembly 4 It is transferred back to and is incubated on block 211 by reaction vessel grabbing assembly 5 again, the detection that shines is carried out to determinand by surveying light part 22.
It is understood that if desired adding substrate, then to the reaction after Magneto separate cleaning in Magneto separate cleaning assembly 4 Container adds substrate, then is transferred back to by reaction vessel grabbing assembly 5 and is incubated for block 211;If substrate needs to mix with determinand, then instead It answers container grabbing assembly 5 to be transferred to reaction vessel in the substrate mixing portion 63 for mixing component 6 from Magneto separate cleaning assembly 4, mixes After even, reaction vessel is transferred back to from the substrate mixing portion 63 for mixing component 6 is incubated for block 211 again by reaction vessel grabbing assembly 5;And And after the determinand for having added substrate needs to be incubated for again, then by survey light part 22 carry out shine detection.
Also, it surveys light part 22 to be set on incubation block 211, i.e., incubation function is integrally disposed with detection function, such energy Enough so that compact integral structure, reduces volume, while also can be shortened the transfer path of reaction vessel, complete machine operational efficiency is improved. Moreover, surveying the trailing flank that light part 22 is located at sample incubation mechanism 21, and it is arranged side by side with Magneto separate cleaning assembly 4, in this way can Reduce occupied space, improves space utilization rate, and then reduce machine volume.
Sample incubation mechanism 21 further includes being set to the heating element for being incubated for 211 lower section of block, and heating element is used for incubation Block 211 heats, and is incubated on block 211 the multiple incubation holes 2111 having in array setting, is incubated for hole 2111 and holds for placing response Device simultaneously carries out incubation operation.Heating element can incubation with heat block 211, reaction vessel can be carried by being incubated for block 211, and to reaction Mixture in container is heated, and realizes the function of incubation.Heating element can be by the mixture in reaction vessel formal Such as from about 34 DEG C of preset temperature are heated to before measurement to wait to ensure to react and be normally carried out.Moreover, multiple incubation holes 2111 can be in appoint Meaning mode is arranged, and in the present embodiment, multiple incubation holes 2111 can increase in array arrangement is incubated for the carrying reaction vessel of block 211 Quantity.Exemplary, incubation block 211 is metal structure, can be conducive to heat in this way and distribute, and then is convenient for incubation with heat block Reaction vessel in 211.Heating element is heating film, and heating film can generate heat after being powered, which can be to incubation block 211 Heating.Certainly, in the other embodiments of the utility model, heating element can also be heater strip, heating rod or other energy The structure enough heated.Moreover, surveying light part 22 is located at the side for being incubated for block 211, facilitating survey light part 22 and sample incubation machine in this way While structure 21 combines, moreover it is possible to survey light part 22 be facilitated to carry out the detection that shines to reaction vessel.
It is understood that the mixture in reaction vessel needs to take some time when being incubated for, reaction vessel is grabbed Take component 5 that the uniformly mixed reaction vessel in the sample mixing portion 62 through mixing seat can be transferred to the incubation hole for being incubated for block 211 In 2111, since the various components of the Full-automatic chemiluminescence immunoassay analysis meter of the utility model move simultaneously, so that each position It has set reaction vessel to be operated, therefore, reaction vessel grabbing assembly 5 can carry out other and operate without the waiting reaction Container incubating is completed, and can such as be carried out being transferred to reaction vessel in sample mixing portion 62, be cleaned reaction vessel from Magneto separate Component 4 is transferred in substrate mixing portion 63 or is transferred to the reaction vessel completed is incubated in Magneto separate cleaning assembly 4.
Optionally, sample incubation mechanism 21 further includes temperature sensor, and temperature sensor, which is set to, to be incubated on block 211, is used The temperature of block 211 is incubated in detection and controls heating element to the heating temperature for being incubated for block 211.Temperature sensor and main control Component 77 is electrically connected, and main control component 77 can also detect the temperature for being incubated for block 211 by temperature sensor, is also passed by temperature Sensor controls heating element and heats to block 211 is incubated for, and adjusts the heating temperature of heating element incubation with heat block 211;Tool Body, temperature sensor is incubated for the output power that 211 temperature of block controls heating element by detection, and it is whole to carry out incubation block 211 Temperature control.If temperature sensor detection incubation 211 temperature of block is relatively low, temperature sensor controls heating element heating, is incubated with being turned up Educate the temperature of block 211;If being incubated for the temperature drift of block 211, temperature sensor controls heating element and stops heating.
Again optionally, sample incubation mechanism 21 further includes temperature switch, and temperature switch, which is set to, to be incubated on block 211, temperature Switch stops heating for controlling heating element.Temperature switch is electrically connected with heating element, temperature detect switch (TDS) also with main control component 77 electrical connections.When the failure of the function of temperature control of temperature sensor, main control component 77 controls temperature switch cutting heating element Power supply realizes high temperature protection, avoids high temperature that the sample in reaction vessel is caused to fail, and guarantees that pattern detection result is accurate.
Further, being incubated on block 211 also has light-measuring hole 2112, and the corresponding light part 22 of surveying of light-measuring hole 2112 is arranged, and position In far from the side for being incubated for hole 2111, the reaction vessel after incubation is transferred in light-measuring hole 2112 from hole 2111 is incubated for, and by surveying Light part 22 carries out the detection that shines.Light opening is surveyed specifically, being incubated on block 211 also and having, which is incubated for hole 2111 With survey light part 22.When detection, reaction vessel is transferred in light-measuring hole 2112 by reaction vessel grabbing assembly 5, surveys light part 22 to anti- The luminous value of determinand in container is answered to be detected, the light that reaction vessel issues can be irradiated to survey light part 22 by surveying light opening On, realize the luminous detection of determinand in reaction vessel.Exemplary, light-measuring hole 2112 is located at the marginal position for being incubated for hole 2111, Survey light part 22 is facilitated to carry out the detection that shines.
It is understood that reaction vessel grabbing assembly 5 directly cleans Magneto separate if determinand is without adding substrate Reaction vessel afterwards is transferred in the light-measuring hole 2112 for being incubated for block 211 from Magneto separate cleaning assembly 4.After if determinand adds substrate Without mix operate, reaction vessel grabbing assembly 5 directly Magneto separate is cleaned after reaction vessel from 4 turns of Magneto separate cleaning assembly It moves on in the incubation hole 2111 for being incubated for block 211, after being incubated for block 211 and carrying out incubation operation to reaction vessel, reaction vessel crawl Reaction vessel is transferred in light-measuring hole 2112 by component 5 from hole 2111 is incubated for again.It is grasped if needing to mix after determinand addition substrate Make, the reaction vessel after reaction vessel grabbing assembly 5 first cleans Magneto separate is transferred to mixing component from Magneto separate cleaning assembly 4 In 6 substrate mixing portion 63, so that the determinand in reaction vessel is uniformly mixed with substrate, then reaction vessel grabbing assembly 5 By reaction vessel from substrate mixing portion 63 be transferred to be incubated for block 211 incubation hole 2111 in, through be incubated for block 211 to reaction vessel into After row incubates operation, reaction vessel is transferred in light-measuring hole 2112 by reaction vessel grabbing assembly 5 from hole 2111 is incubated for again.
As an embodiment, Full-automatic chemiluminescence immunoassay analysis meter further includes removal waste fluid component 7, removal waste fluid group Part 7 is movably disposed in the left side for being incubated for block 211.Removal waste fluid component 7 is used to that the waste liquid after detected in reaction vessel be discharged, While removal waste fluid, removal waste fluid component 7 can also carry out the reaction vessel shading detected that shines to being incubated for survey in optical assembly 2.
Further, being incubated on block 211 also has waste discharge fluid apertures 2113, waste discharge fluid apertures 2113 and light-measuring hole 2112 side by side and It is disposed adjacent, to the reaction vessel shading in light-measuring hole 2112 when the waste liquid in reaction vessel is discharged in the decline of removal waste fluid component 7.It is single Solely setting waste discharge fluid apertures 2113, the reaction vessel after can will test to removal waste fluid is transferred in waste discharge fluid apertures 2113, then will be to The reaction vessel of detection is transferred in light-measuring hole 2112, and luminous detection process is carried out simultaneously with removal waste fluid process, is kept away Exempt to occupy the influence detection of light-measuring hole 2112 to the reaction vessel of removal waste fluid, improves complete machine operational efficiency.Moreover, removal waste fluid component 7 Waste liquid in reaction vessel can be discharged, specifically, removal waste fluid component 7 can extend into waste discharge when removal waste fluid component 7 declines In reaction vessel at fluid apertures 2113, and the waste liquid in reaction vessel is discharged, after the completion of waste liquid discharge, on removal waste fluid component 7 It rises and resets.In this way, can be kept away after the reaction vessel after discharge waste liquid is discarded into ash can 99 by reaction vessel grabbing assembly 5 Exempting from waste liquid sinuous flow leads to the problem of polluting and influencing environment.Moreover, waste discharge fluid apertures 2113 is disposed adjacent with light-measuring hole 2112, energy The transfer path for enough reducing reaction vessel, improves the transfer efficiency of reaction vessel grabbing assembly 5, moreover it is possible to so that compact integral structure It is small and exquisite.
Moreover, removal waste fluid component 7 can also play interception.While removal waste fluid, the decline of removal waste fluid component 7 can be hidden Light-measuring hole 2112 is kept off, to realize the shading to reaction vessel in light-measuring hole 2112, improves and surveys the accuracy that light part 22 detects sample. After reaction vessel is transferred to light-measuring hole 2112, removal waste fluid component 7 declines, and can cover the reaction vessel at shading hole, keeps away Exempt from external light source to be irradiated on determinand by light-measuring hole 2112.Surveying the luminous value that light part 22 detects in this way is only determinand Luminous value guarantees that pattern detection result is accurate and reliable so that the light in external environment will not be detected by surveying light part 22.
Reaction vessel after detection can be transferred to waste discharge fluid apertures from light-measuring hole 2112 by reaction vessel grabbing assembly 5 2113, reaction vessel grabbing assembly 5 will also be incubated for reaction vessel to be detected in hole 2111 and be transferred in light-measuring hole 2112;With Afterwards, removal waste fluid component 7 declines, while so that removal waste fluid component 7 is extend into the reaction vessel of waste discharge fluid apertures 2113, removal waste fluid Component 7 can also cover the reaction vessel at light-measuring hole 2112.While realizing removal waste fluid by the up and down motion of removal waste fluid component 7, Also it is able to achieve the shading of light-measuring hole 2112.In this way, main control component 77 controls the waste liquid in the absorption reaction vessel of removal waste fluid component 7 When, moreover it is possible to the luminous value that light part 22 detects determinand in reaction vessel in light-measuring hole 2112 is surveyed in control, can be improved complete machine in this way Operational efficiency.It should be noted that the waste liquid that removal waste fluid component 7 is discharged passes through in the waste liquid barrel that fluid path component 8 is discharged, this point It is described in detail later.
Certainly, it in the other embodiments of the utility model, can also only be realized by a light-measuring hole 2112.Specifically , reaction vessel is transferred in light-measuring hole 2112, and removal waste fluid component 7 declines, and to block the reaction vessel at light-measuring hole 2112, is surveyed After light part 22 carries out luminous detection, the waste liquid in reaction vessel is discharged again for removal waste fluid component 7.
Exemplary, removal waste fluid component 7 includes lifting slider component, removal waste fluid needle and hood, and lifting slider component can be transported Dynamic setting, removal waste fluid needle and hood are all set on lifting slider component.Lifting carriage component be able to drive removal waste fluid needle and Hood, which synchronizes, to be risen or fallen.When lifting slider component drives removal waste fluid needle and hood to synchronize decline, removal waste fluid needle can It extend into the reaction vessel at waste discharge fluid apertures 2113, meanwhile, hood is provide on the reaction vessel at light-measuring hole 2112.Preferably Ground, hood are incubated for block 211 and card slot are arranged at shading hole, the edge of hood, which can block, to be set at bung shape structure is similar to In card slot, guarantee shading reliability, and then guarantee the reliability of pattern detection.
Optionally, sample incubation mechanism 21 further includes substrate preheating structure 212.Substrate preheating structure 212 is the bottom of for realizing The preheating of object facilitates in order to which substrate is reacted with determinand and is incubated for block 211 to the substrate and determinand in subsequent reaction vessel Incubation operation is carried out, preheating time is shortened, improves processing speed.Substrate preheating structure 212 includes that substrate economizer bank and substrate are led Heat block, substrate economizer bank and substrate heat-conducting block, which are all set in, to be incubated in block 211, and substrate heat-conducting block is for heating in substrate economizer bank Substrate.The performance that can be guaranteed substrate using substrate economizer bank is avoided substrate from failing and influences the accuracy of pattern detection.Bottom Object heat-conducting block have the characteristics that it is thermally conductive fast, can quickly will be incubated for block 211 on heat transfer to substrate economizer bank on, realize Heating to substrate.In the present embodiment, substrate economizer bank can be non-metallic pipe, or metal tube.Preferably, substrate For economizer bank to be wound on substrate heat-conducting block to spiral way, the substrate in substrate economizer bank is heated in realization.Such energy Enough increase contact area, guarantees heating effect.Certainly, in the other embodiments of the utility model, it also can be used directly and incubate It educates block 211 to heat substrate economizer bank, i.e., without using substrate heat-conducting block.
Again optionally, sample incubation mechanism 21 further includes cleaning solution preheating container 213.Cleaning solution preheating container 213 can Cleaning solution is heated, the reduction of determinand temperature is avoided, is reacted convenient for determinand, facilitates and is incubated for block 211 in subsequent reaction vessel Substrate and determinand carry out incubation operation, shorten preheating time, improve processing speed.Cleaning solution preheating container 213 is set to It is incubated in block 211, for heating cleaning solution, and the cleaning solution after heating can be delivered in reaction vessel.The pre- thermal capacitance of cleaning solution Device 213 is heated by being incubated for block 211, is heated with realizing to the cleaning solution in cleaning solution preheating container 213.Pass through The cleaning solution after preheating container 213 heats is separated by feed track Magneto separate cleaning assembly 4, to the determinand in reaction vessel And impurity is cleaned, and impurity is removed.
In principle, the position of waste discharge fluid apertures 2113, light-measuring hole 2112 and incubation hole 2111 is unrestricted, as long as can be realized Corresponding function.In the present embodiment, the hole 2111 that is incubated for of array distribution is located at the front side for being incubated for block 211, waste discharge fluid apertures 2113 and light-measuring hole 2112 be located at the rear side of reaction vessel, correspondingly, surveying light part 22 is set to the rear side for being incubated for block 211.And And substrate preheating structure 212 and cleaning solution preheating container 213 also are located at the rear side for being incubated for block 211.
The incubation of the utility model surveys optical assembly 2 in addition to integrated incubation function and light measuring function, also takes into account removal waste fluid function, So that it is compact-sized to be incubated for survey optical assembly 2;Match moreover, being incubated for block 211 with substrate preheating structure 212, cleaning solution preheating container 213 It closes, can make full use of the thermal energy being incubated on block 211, reduce required heating component on Full-automatic chemiluminescence immunoassay analysis meter Quantity realizes the integrated of a variety of function of temperature control in an only heating component, realizes that sample incubation, substrate incubation, substrate are pre- Heat, the function of cleaning solution preheating;And light measuring function is realized by being incubated for block 211 and surveying the cooperation of light part 22.Light is surveyed using being incubated for Enabling to the Full-automatic chemiluminescence immunoassay analysis meter of the utility model to have after component 2, structure is simple, small in size, cost Low, energy conservation and environmental protection, the feature of safety.
Referring to Fig. 1, Figure 12, Figure 13 and Figure 15, as an embodiment, Magneto separate cleaning assembly 4 is discoid knot Structure, including Magneto separate pedestal 41, cleaning solution injecting mechanism 42, cleaning solution output mechanism 43 and Magneto separate adsorbing mechanism 48.Magnetic point Play carrying the bottom of from, for carrying each components of Magneto separate cleaning assembly 4, while Magneto separate pedestal 41 can also carry to The reaction vessel of cleaning.Reaction vessel is surveyed on optical assembly 2 from incubation and is transferred to Magneto separate pedestal by reaction vessel grabbing assembly 5 On 41, after the cleaning of Magneto separate cleaning assembly 4, reaction vessel grabbing assembly 5 again turns reaction vessel from Magneto separate pedestal 41 It removes.If adding substrate, after substrate (substrate here is heated by incubation block 211) has been added on Magneto separate pedestal 41, instead Container grabbing assembly 5 is answered again to move away reaction vessel from Magneto separate pedestal 41.Cleaning solution injecting mechanism 42 and fluid path component 8 Connection, can inject cleaning solution (cleaning solution here is heated by incubation block 211), clearly into the reaction vessel of Magneto separate pedestal 41 Washing lotion output mechanism 43 is connect with fluid path component 8, after waste liquid and cleaning capable of being cleaned in the reaction vessel of Magneto separate pedestal 41 Cleaning solution discharge.It is understood that cleaning solution injecting mechanism 42 injects the step of cleaning solution in cleaning solution output mechanism 43 It is carried out before cleaning solution is discharged.Moreover, cleaning solution injecting mechanism 42 and cleaning solution output mechanism 43 use in pairs.
Exemplary, the quantity of cleaning solution injecting mechanism 42 and cleaning solution output mechanism 43 is multiple.In the present embodiment, The quantity of cleaning solution injecting mechanism 42 and cleaning solution output mechanism 43 is three.Three cleaning solution injecting mechanisms 42 and three are clear Washing lotion output mechanism 43 is interspersed on Magneto separate pedestal 41, i.e. cleaning solution is respectively set in the two sides of cleaning solution output mechanism 43 Cleaning solution output mechanism 43 is respectively set in injecting mechanism 42, the two sides of cleaning solution injecting mechanism 42.It is understood that cleaning solution Conveying and output realize that this point is described in detail later by fluid path component 8.
With manhole appendix 411 and the cleaning solution inlet opening 412 and cleaning solution drainage hole that are sequentially arranged on Magneto separate pedestal 41 413.For manhole appendix 411 for being put into or taking out reaction vessel to be separated, it is anti-that Magneto separate pedestal 41 drives reaction vessel rotation to make Container is answered sequentially to correspond to cleaning solution inlet opening 412, cleaning solution drainage hole 413 and manhole appendix 411.Cleaning solution injecting mechanism 42 is arranged In cleaning solution inlet opening 412, for adding cleaning solution into reaction vessel.The liftable correspondence of cleaning solution output mechanism 43 is clear Washing lotion drainage hole 413 is arranged, the cleaning waste liquid for being discharged in reaction vessel.Reaction vessel grabbing assembly 5 by reaction vessel from It is incubated on block 211 and is placed into Magneto separate pedestal 41 through manhole appendix 411, Magneto separate pedestal 41 drives reaction vessel from manhole appendix It is turned at 411 at cleaning solution inlet opening 412, is added to reaction at the cleaned liquid inlet opening 412 of cleaning solution injecting mechanism 42 and holds In device, then, Magneto separate pedestal 41 drives reaction vessel from cleaning solution drainage hole 413, and cleaning solution output mechanism 43 is cleaned Cleaning waste liquid in reaction vessel is discharged liquid drainage hole 413;Finally, Magneto separate pedestal 41 drives reaction vessel to arrange from cleaning solution Fluid apertures 413 turns at manhole appendix 411, and reaction vessel grabbing assembly 5 takes out reaction vessel.
It is understood that Magneto separate pedestal 41 is driving reaction vessel to turn to cleaning solution inlet opening from manhole appendix 411 After 412, next reaction vessel can also be placed into Magneto separate pedestal 41 by reaction vessel grabbing assembly 5 through manhole appendix 411, real Now continuous separation cleaning operation improves complete machine operational efficiency.If the number of cleaning solution injecting mechanism 42 and cleaning solution output mechanism 43 Amount is multiple, correspondingly, the quantity of cleaning solution inlet opening 412 and cleaning solution drainage hole 413 is also multiple.At this point, Magneto separate Pedestal 41 drive reaction vessel returned to after multiple cleaning solution inlet openings 412 and cleaning solution drainage hole 413 from manhole appendix 411 into Portal 411, realizes that the separating for several times cleaning of determinand in reaction vessel is improved further to remove the impurity in reaction vessel The purity of determinand.
Moreover, Magneto separate pedestal 41 includes Magneto separate pot, Magneto separate cover board, Magneto separate bracket and Magneto separate driving structure, Magneto separate bracket is rotatablely arranged in Magneto separate pot, and Magneto separate driving structure drives Magneto separate bracket in Magneto separate pot transfer It is dynamic.Magneto separate cover plate lid is set on Magneto separate pot, and Magneto separate cover board is static structures, is fixed on Magneto separate pot.Magneto separate branch The hole location of multiple placing response containers is set on frame, and multiple hole locations are uniformly distributed on Magneto separate bracket, and two adjacent holes Spacing between position is equal to spacing between manhole appendix 411 and cleaning solution inlet opening 412, also equal to cleaning solution inlet opening 412 with Spacing between cleaning solution drainage hole 413.Manhole appendix 411, cleaning solution inlet opening 412 and cleaning solution drainage hole 413 are set to magnetic It separates on cover board, and respectively corresponds the hole location on Magneto separate bracket.It is understood that the size of manhole appendix 411 is greater than reaction Reaction vessel can be placed on Magneto separate bracket by the maximum outside diameter of container, reaction vessel grabbing assembly 5 through manhole appendix 411, After the completion of placement, the top of reaction vessel will not expose Magneto separate cover board.Magneto separate driving structure drives Magneto separate bracket in magnetic When rotating in separation pot, reaction vessel is able to drive in the rotated down of Magneto separate cover board, and respectively correspond cleaning solution inlet opening 412 with cleaning solution drainage hole 413.Exemplary, Magneto separate driving structure can cooperate synchronous band structure or gear structure for motor Etc..
It is once a test beat that Magneto separate driving structure, which drives Magneto separate holder pivots, former in the test beat The reaction vessel come at manhole appendix 411 turns at cleaning solution inlet opening 412, and the reaction originally at cleaning solution inlet opening 412 is held Device turns at cleaning solution drainage hole 413, and originally the reaction vessel at cleaning solution drainage hole 413 turns at manhole appendix 411, will Reaction vessel after separation cleaning takes out from manhole appendix 411, then again by the reaction vessel of cleaning to be separated through manhole appendix 411 It is put into, meanwhile, cleaning solution injecting mechanism 42 adds cleaning solution, cleaning solution row into the reaction vessel at cleaning solution inlet opening 412 The cleaning waste liquid in the reaction vessel at cleaning solution drainage hole 413 is discharged for mechanism 43 out.
Further, Magneto separate cleaning assembly 4 further includes drain lifting unit 45 and Magneto separate swab 44.Magneto separate cleaning group The cleaning solution output mechanism 43 of part 4 includes drain needle.Magneto separate swab 44 can clean the outer surface of drain needle, keep away Exempt under the remaining cleaning waste liquor contamination of drain needle outer wall one wait clear the determinand washed in waste liquid, guarantees the accurate of pattern detection It is fixed.Moreover, the setting of Magneto separate swab 44 is also avoided that drain needle is transferred to other service sinks 35 and is cleaned, drain needle is improved Drain efficiency.
Cleaning solution output mechanism 43 is installed on drain lifting unit 45, and control cleaning solution output mechanism 43 is facilitated to decline and be discharged Waste liquid is cleaned, rises after the completion of cleaning, will not influence the rotation of Magneto separate bracket.Drain lifting unit 45 is liftably set to magnetic On detachable base 41.Installation of the drain lifting unit 45 for realizing cleaning solution output mechanism 43, the lifting of drain lifting unit 45 Movement can be realized the discharge that waste liquid is cleaned in reaction vessel.When drain lifting unit 45 declines, cleaning solution output mechanism 43 is protruded into In reaction vessel, and cleaning waste liquid is discharged, after the completion, drain lifting unit 45 drives the rising of cleaning solution output mechanism 43 to reset.
Drain needle is set on drain lifting unit 45, and Magneto separate swab 44 is set in cleaning solution drainage hole 413, drain liter When drop portion 45 drives drain needle down or up, outer wall washing of the Magneto separate swab 44 to drain needle.Specifically, drain lifting unit 45 include vertical mounting plate and vertical displacement movement structure, and vertical mounting plate is set in vertical displacement movement structure, vertical to rise Drop motion structure is liftably set on Magneto separate pedestal 41.Vertical displacement movement structure is able to drive vertical mounting plate and rises Drop movement.It is understood that vertical displacement movement structure can cooperate feed screw nut's structure using motor, lifting can also be cooperated Sliding block etc. can be realized the structure of elevating movement.
Drain needle is installed in the vertical mounting plate of drain lifting unit 45, and vertical displacement movement structure drives vertical mounting plate When moving up and down, drain needle can be driven to move up and down simultaneously.Specifically, vertical displacement movement structure passes through right angle setting Strip moves the decline of drain needle, and drain needle passes through Magneto separate swab 44 and extend into the corresponding reaction vessel of cleaning solution drainage hole 413, After drawing the cleaning waste liquid in reaction vessel, vertical displacement movement structure drives drain needle to rise by vertical mounting plate, drain Needle rises in Magneto separate swab 44, and is detached from reaction vessel.Drain needle is during decline is with rising, 44 energy of Magneto separate swab It is enough that the outer wall of drain needle is cleaned.Exemplary, cleaning solution drainage mechanism further includes drain needle mounting base, drain needle mounting base It is installed in vertical mounting plate, drain needle is installed in drain needle mounting base.
It is understood that Magneto separate swab 44 has separation cleaning pilot hole, cleaning solution cleaning import and cleaning solution clear Mouth is washed out, drain needle is moved up and down along separation cleaning pilot hole, realizes the cleaning waste liquid drawn in reaction vessel.Cleaning solution is clear It washes import and is connected to respectively with fluid path component 8 with cleaning solution washing outlet, realize conveying and output cleaning solution.Cleaning solution is from cleaning solution Cleaning import enters in Magneto separate swab 44, and is in contact with the drain needle in separation cleaning pilot hole, to clean drain needle Outer wall, after the completion of cleaning, cleaning waste liquid is discharged in waste liquid barrel by cleaning solution washing outlet through fluid path component 8.
Still further, 4 cleaning solution injecting mechanism 42 of Magneto separate cleaning assembly includes injection needle and fluid injection needle stand, injection needle Seat is fixed on cleaning solution inlet opening 412, and injection needle is connect with fluid path component 8, and is set on fluid injection needle stand, and injection needle is used for will Cleaning solution is added in reaction vessel.The tail portion of injection needle is connect with fluid path component 8, real to convey cleaning solution into injection needle Now cleaning solution is transported in reaction vessel by injection needle.Moreover, the angle between injection needle and fluid injection needle stand is less than 90 °, In this way, cleaning solution is also added in reaction vessel in an inclined manner, cleaning solution can be directly injected into the side wall of reaction vessel On, effectively to break up the magnetic bead on reaction vessel side wall, reduce the residual quantity of impurity such as enzyme etc..
Preferably, Magneto separate cleaning assembly 4 further includes magnetic shielding part 47, magnetic shielding part 47 is sheathed on Magneto separate pedestal 41 outside, for shielding the magnetic field of the generation of Magneto separate adsorbing mechanism 48.Since the magnet of absorption magnetic bead has very high magnetic field Intensity, the magnetic field that magnet generates can be surveyed to light part 22 (generally PMT, photomultiplier tube, photomultiplier tube) is surveyed The accuracy and reliability of light has an impact.In the Full-automatic chemiluminescence immunoassay analysis meter of the utility model, to reduce magnetic Influence to surveying light part 22 and surveying light, is magnetic screen in the drum of one magnetic material of periphery design of Magneto separate pedestal 41 Component 47,47 sets of the magnetic shielding part outsides in Magneto separate pedestal 41.Magnetic shielding part 47 is avoiding magnetic field influence survey light part 22 Under the premise of detection performance, Magneto separate cleaning assembly 4 is allowed to reduce equipment instrument with close place of light part 22 is surveyed.At this In embodiment, Magneto separate cleaning assembly 4 can be arranged side by side with light part 22 is surveyed.
Optionally, on Magneto separate pedestal 41 also have substrate injection hole 46, substrate injection hole 46 be located at manhole appendix 411 with clearly Between washing lotion drainage hole 413, an extension end of fluid path component 8 is protruded into substrate injection hole 46, can be to substrate injection hole 46 Substrate is added in reaction vessel.That is, also adding substrate at Magneto separate cleaning assembly 4, it can reduce individually set in this way Bottom set object adds mechanism, reduces overall volume.One extension end of fluid path component 8 here refers to that the substrate of fluid path component 8 is defeated Send an end of the substrate discharge line 822 of liquid channel system 82.The substrate conveying liquid channel system 82 and substrate of fluid path component 8 are infused Enter the connection of hole 46, and substrate is added into reaction vessel by substrate injection hole 46.It is understood that Magneto separate cleaning assembly 4 further include substrate injecting mechanism, and substrate injecting mechanism is set in substrate injection hole 46, and substrate injecting mechanism and substrate convey liquid The substrate discharge line 822 of road system 82 connects, to add substrate into reaction vessel.Substrate injecting mechanism include injection pipe and Tube socket, tube socket are set in substrate injection hole 46, and one end of injection pipe and the substrate discharge line 822 of substrate injecting mechanism connect It connects.
Referring to Fig. 1 and Figure 14, as an embodiment, Full-automatic chemiluminescence immunoassay analysis meter further includes two bottoms Object loading part, substrate loading station is in the front side of sample reagent loading assembly 1, for carrying substrate container, and will by pipeline Substrate in substrate container is transported in reaction vessel after the preheating of substrate economizer bank by substrate injection hole 46.Specifically, substrate Loading part is set to the forward right side of carrying platform, in this way, enabling to substrate container to lean on after substrate loading part loads substrate container Nearly user facilitates user to replace substrate container, and substrate container introduces substrate economizer bank and substrate injection hole by pipeline, realizes The conveying of substrate.
Specifically, Full-automatic chemiluminescence immunoassay analysis meter further includes substrate constant displacement pump SR3, substrate constant displacement pump SR3 is located at On carrying platform, and it is set to the front side of sample reagent loading assembly 1, substrate constant displacement pump SR3 is respectively communicated with substrate by pipeline Container, substrate economizer bank and substrate injection hole 46 provide power for the conveying of substrate.
Specifically, fluid path component 8 includes that substrate conveys liquid channel system 82, substrate conveys liquid channel system 82 and is used for Magneto separate Cleaning assembly 4 conveys substrate, and substrate is transported in the reaction vessel after cleaning by Magneto separate cleaning assembly 4.Substrate is defeated Sending liquid channel system 82 includes that substrate suction pipe 821, substrate discharge line 822 and the first substrate control valve V821, substrate are quantitative SR3 is pumped by the first substrate control valve V821 connection substrate suction pipe 821 and substrate discharge line 822, for holding from substrate The substrate of predetermined amount is drawn in device and substrate is added into reaction vessel.
It is understood that one end of substrate suction pipe 821 is extend into substrate container, substrate suction pipe 821 The other end is connect by the first substrate control valve V821 with substrate constant displacement pump SR3, and substrate constant displacement pump SR3 also passes through the first substrate control Valve V821 processed is connect with one end of substrate discharge line 822, the other end and Magneto separate cleaning assembly 4 of substrate discharge line 822 Connection.First substrate control valve V821 is connected to substrate constant displacement pump SR3 and substrate suction pipe 821, simultaneously turns off substrate constant displacement pump SR3 and substrate discharge line 822, at this point, substrate constant displacement pump SR3 drawn by substrate suction pipe 821 it is clear in substrate container Washing lotion;Then, the first substrate control valve V821 turns off substrate constant displacement pump SR3 and substrate suction pipe 821, meanwhile, it is connected to substrate Constant displacement pump SR3 and substrate discharge line 822, at this point, substrate constant displacement pump SR3 can be by the substrate of absorption through substrate discharge line 822 are transported in Magneto separate cleaning assembly 4, and then by Magneto separate cleaning assembly 4 are transported to substrate anti-after separation cleaning It answers in container.It is understood that the control valve in the utility model can use two-position three-way valve, multidigit multiple-way valve or three Port valve cooperates two switch valves etc. to realize on-off control.
Further, substrate conveying liquid channel system 82 further includes the second substrate control valve V822, the second substrate control valve V822 is set on substrate suction pipe 821, for drawing the substrate at least two substrate containers.In the present embodiment, bottom The quantity of object container is two, correspondingly, two substrates, which are arranged, in substrate suction pipe 821 draws branch pipe, two substrates draw branch One end of pipe passes through the second substrate control valve V822 and substrate suction pipe 821 respectively, and two substrates draw the other end of branch pipe It is respectively protruding into corresponding substrate container, and the second substrate control valve V822 turns off one of substrate and draws branch pipe and substrate suction While taking pipeline 821, it is connected to another substrate and draws branch pipe and substrate suction pipe 821.It can be by controlling the second substrate control The position of valve V822 processed realizes that substrate suction pipe 821 switches between two bottom of bottle object containers, certainly, can also only use one bottle Substrate in substrate container after the completion of use, then switches the second substrate control valve V822, realizes substrate in empty substrate container Addition.
Moreover, substrate economizer bank is set on substrate discharge line 822.Preferably, substrate economizer bank is substrate discharge pipe The a part on road 822, to be heated to the substrate being transported in Magneto separate cleaning assembly 4.Certainly, in the utility model In other embodiments, substrate economizer bank is to be incubated for a part fixed in block 211, the both ends access substrate warp of substrate economizer bank In substrate discharge line 822.
Referring to Fig. 1, Figure 12, Figure 13, Figure 17 to Figure 19, as an embodiment, immune point of Full-automatic chemiluminescence Analyzer further includes Magneto separate syringe SR4, and Magneto separate syringe SR4 is located at the lower section of carrying platform, specifically, Magneto separate is injected Device SR4 is located at the left side (specifically, being located at position to the rear on the left of carrying platform) of carrying platform, and Magneto separate syringe SR4 passes through Pipeline is connect with injection needle, and cleaning solution is delivered in reaction vessel, and Magneto separate syringe SR4 also passes through pipeline and wipes with Magneto separate Son 44 connects, and cleaning solution is supplied to Magneto separate swab 44.
Specifically, fluid path component 8 further includes Magneto separate cleaning liquid channel system 83.Magneto separate cleans liquid channel system 83 for real The conveying of cleaning solution and the discharge of cleaning waste liquid in existing Magneto separate cleaning assembly 4.Specifically, Magneto separate cleans liquid channel system 83 Including Magneto separate imbibition pipeline 831, Magneto separate fluid injection pipeline 832 and the first Magneto separate control valve V831.Magneto separate syringe SR4 It is connected to respectively with Magneto separate imbibition pipeline 831 and Magneto separate fluid injection pipeline 832 by the first Magneto separate control valve V831, Magneto separate Imbibition pipeline 831 is connect with the soda liquor container connection Magneto separate fluid injection pipeline 832 with cleaning solution with injection needle.First magnetic point From control valve V831 connection Magneto separate syringe SR4 and Magneto separate imbibition pipeline 831, shutdown Magneto separate syringe SR4 and magnetic point From fluid injection pipeline 832, the cleaning solution in Magneto separate container can be drawn;First Magneto separate control valve V831 is connected to Magneto separate injection Device SR4 and Magneto separate fluid injection pipeline 832, shutdown Magneto separate syringe SR4 and Magneto separate imbibition pipeline 831 can hold to reaction Cleaning solution is injected in device.
Magneto separate syringe SR4 is the power source that cleaning solution is drawn and is discharged.Exemplary, Magneto separate syringe SR4 is note Emitter, constant displacement pump or other power source structures.One end of first Magneto separate control valve V831 and Magneto separate syringe SR4 connect Connect, the another both ends of the first Magneto separate control valve V831 respectively with one end of Magneto separate imbibition pipeline 831 and Magneto separate fluid injection pipeline 832 one end connection, the other end of Magneto separate imbibition pipeline 831 are extend into soda liquor container, Magneto separate fluid injection pipeline 832 The other end is connect with injection needle.When drawing cleaning solution, the first Magneto separate control valve V831 is connected to Magneto separate syringe SR4 and magnetic point While from imbibition pipeline 831, shutdown Magneto separate syringe SR4 and Magneto separate fluid injection pipeline 832, at this point, Magneto separate syringe SR4 can draw the cleaning solution in soda liquor container, and be stored in Magneto separate syringe SR4.It is added into reaction vessel clear When washing lotion, while the first Magneto separate control valve V831 turns off Magneto separate syringe SR4 and Magneto separate imbibition pipeline 831, connection Magneto separate syringe SR4 and Magneto separate fluid injection pipeline 832, at this point, Magneto separate syringe SR4 can be by the cleaning solution of absorption through infusing Liquid needle is added in reaction vessel.Cleaning solution is realized from the absorption in soda liquor container and is added in reaction vessel.
Magneto separate, which cleans liquid channel system 83, to convey cleaning solution to Magneto separate swab 44.Further, Magneto separate cleans Liquid channel system 83 further includes the first Magneto separate detergent line 834, third Magneto separate control valve V833 and the 4th Magneto separate control valve V834.First Magneto separate detergent line 834 connects Magneto separate fluid injection pipeline 832 and Magneto separate swab 44, the control of third Magneto separate Valve V833 is set in the first Magneto separate detergent line 834, for controlling the on-off of the first Magneto separate detergent line 834.4th Magneto separate control valve V834 is set on Magneto separate fluid injection pipeline 832.Magneto separate syringe SR4 is through Magneto separate fluid injection pipeline 832 It is connected to the first Magneto separate detergent line 834, the 4th Magneto separate control valve V834 turns off Magneto separate fluid injection pipeline 832, for clear Wash the outer wall of injection needle.
Specifically, one end of the first Magneto separate detergent line 834 is connect with Magneto separate fluid injection pipeline 832, the first Magneto separate The other end of detergent line 834 is connect with the cleaning import of the cleaning solution of Magneto separate swab 44, and third Magneto separate control valve V833 is set It is placed in the first Magneto separate detergent line 834, for controlling the on-off of the first Magneto separate detergent line 834.Moreover, the 4th magnetic point It is set on Magneto separate fluid injection pipeline 832 from control valve V834, for controlling the on-off of Magneto separate fluid injection pipeline 832.To magnetic point When conveying cleaning solution from swab 44, the 4th Magneto separate control valve V834 shutdown separation fluid injection pipeline, third Magneto separate control valve V833 opens the first Magneto separate detergent line 834, and cleaning liquid syringe enters the cleaned liquid fluid injection pipeline of the cleaning solution of absorption To the first Magneto separate detergent line 834, then import is cleaned by cleaning solution and is entered in Magneto separate swab 44, to cleaning solution fluid injection The outer surface of needle is cleaned.When injecting cleaning solution into reaction vessel, third Magneto separate control valve V833 turns off the first magnetic Separation cleaning pipeline 834, the 4th Magneto separate control valve V834 open separation fluid injection pipeline.It is understood that the 4th Magneto separate Position of the control valve V834 on cleaning solution liquid injection pipe road dispenses detergent line 812 positioned at cleaning solution fluid injection pipeline and first Between junction and cleaning solution fluid injection pipeline and the junction of injection needle.The cleaning solution for enabling to syringe to draw in this way can It flows into corresponding container, avoid sinuous flow and influences the reliability of pattern detection.
Moreover, the cleaning waste liquid in Magneto separate cleaning assembly 4 can also be discharged for Magneto separate cleaning liquid channel system 83, specifically , the cleaning waste liquid in reaction vessel is discharged.Specifically, Full-automatic chemiluminescence immunoassay analysis meter further include vacuum chamber SR51 with First vacuum pump SR53, vacuum chamber SR51 and the first vacuum pump SR53 are located at the rear side of carrying platform (specifically, it is flat to be located at carrying Position to the left on rear side of platform), the outlet of vacuum chamber SR51 connect with the first vacuum pump SR53, vacuum chamber SR51 entrance pass through pipeline and Magneto separate cleaning assembly 4 connects, and waste liquid is cleaned in the reaction vessel after being cleaned by vacuum chamber SR51 for Magneto separate cleaning assembly 4 Discharge provides power, and it is to incubate by vacuum chamber SR51 that the entrance of vacuum chamber SR51, which also passes through pipeline and connect with survey optical assembly 2 is incubated for, It educates and the discharge offer power that optical assembly 2 carries out waste liquid after luminous detection is provided.That is, Magneto separate cleaning liquid channel system 83 is adopted It is Magneto separate driving source 51 with vacuum chamber SR51 and the first vacuum pump SR53, realizes the discharge for cleaning waste liquid in reaction vessel.The One vacuum pump SR53 can provide stable negative pressure for vacuum chamber SR51, so that vacuum chamber SR51 has enough negative pressure that can arrange The cleaning waste liquid of Magneto separate component 4 and the waste liquid being incubated for after being detected in survey optical assembly 2 out.Also, the negative pressure of vacuum chamber SR51 Stablize, stability of flow, can be avoided suction force shakiness and siphon away the magnetic bead in reaction vessel, guarantee cleaning effect, Jin Erbao It is accurate to demonstrate,prove testing result.
Magneto separate cleaning liquid channel system 83 further includes Magneto separate drain line 833, the second Magneto separate control valve V832 and returns Closed tube road 835.Magneto separate drain line 833 connects Magneto separate driving source SR5 and drain needle, and the second Magneto separate control valve V832 is set It is placed in Magneto separate drain line 833, the cleaning waste liquid for being discharged in reaction vessel.Magneto separate driving source SR5 is also connected with back Closed tube road 835, recovered pipeline 835 will be cleaned in reaction vessel in waste liquid discharge waste liquid barrel.Magneto separate driving source SR5 is separation The power source of waste liquid discharge is cleaned after cleaning.
Second Magneto separate control valve V832 is used to control the on-off of Magneto separate drain line 833.Hold when needing to be discharged reaction When cleaning waste liquid in device, the second Magneto separate control valve V832 is opened, so that Magneto separate drain line 833 is access, at this point, magnetic Driving source SR5 is separated by Magneto separate drain line 833 through the cleaning waste liquid in drain needle absorption reaction vessel, and by recovery tube Road 835 is discharged in waste liquid barrel.After the completion of cleaning waste liquid discharge, the second Magneto separate control valve V832 is closed, at this point, separation is dynamic Power source can not clean waste liquid in discharge.
It is understood that waste liquid barrel is located at the lower section of carrying platform, after waste liquid barrel is filled, waste liquid barrel can be taken out, And the waste liquid in waste liquid barrel is emptied, then waste liquid barrel is put into Full-automatic chemiluminescence immunoassay analysis meter again.Moreover, waste liquid barrel It can be a part of Full-automatic chemiluminescence immunoassay analysis meter, be also independent from Full-automatic chemiluminescence immunoassay analysis meter setting.
Also, the cleaning waste liquid in Magneto separate swab 44 can also be discharged in Magneto separate cleaning liquid channel system 83.Magneto separate cleaning Liquid channel system 83 further includes the second Magneto separate detergent line 836 and the 5th Magneto separate control valve V835.Second Magneto separate cleaning pipe Road 836 connects Magneto separate swab 44 and Magneto separate driving source SR5, and the 5th Magneto separate control valve V835 is set to the second Magneto separate It is by Magneto separate driving source SR5 that cleaning is useless for controlling the on-off of the second Magneto separate detergent line 836 in detergent line 836 Liquid is discharged in waste liquid barrel.
The cleaning solution washing outlet of one end connection Magneto separate swab 44 of second Magneto separate detergent line 836, the second magnetic point The other end from detergent line 836 connects Magneto separate driving source SR5.When removal waste fluid, the 5th Magneto separate control valve V835 opens the Two Magneto separate detergent lines 836 are discharged in waste liquid barrel by Magneto separate driving source SR5 by waste liquid is cleaned.After the completion of removal waste fluid, 5th Magneto separate control valve V835 turns off the second Magneto separate detergent line 836.
Preferably, the Magneto separate driving source SR5 of Full-automatic chemiluminescence immunoassay analysis meter further includes B/P EGR Back Pressure Transducer EGR SR52, Vacuum chamber SR51 connection Magneto separate drain line 833 and recovery pipe 835, the first vacuum pump SR53 are set to recovery pipe 835 On, B/P EGR Back Pressure Transducer EGR SR52 is used to detect the pressure of vacuum chamber SR51, and is adjusted by the first vacuum pump SR53.Vacuum chamber Cooperation between SR51, the first vacuum pump SR53 and B/P EGR Back Pressure Transducer EGR SR52 is capable of forming the negative pressure power source of controllable pressure, replaces Peristaltic pump used at present is changed, cost is can reduce in this way, while failure rate can also be reduced, maintains easily.
Moreover, Magneto separate cleaning liquid channel system 83 further includes the 6th Magneto separate control valve V836, the 6th Magneto separate control valve V836 is set in recovery pipe 835, the 6th Magneto separate control valve V836 be also connected with the second Magneto separate detergent line 836 with it is true Empty room SR51, for being respectively communicated with recovery pipe 835 and vacuum chamber SR51 and the second Magneto separate detergent line 836.Specifically, One end of 6th Magneto separate control valve V836 connects recovery pipe 835, and the another both ends of the second Magneto separate control valve V832 connect respectively Meet vacuum chamber SR51 and the second Magneto separate detergent line 836.
While 6th Magneto separate control valve V836 is connected to vacuum chamber SR51 and recovery pipe 835, the second Magneto separate is turned off Detergent line 836 and recovery pipe 835, at this point, the waste liquid in reaction vessel can pass through Magneto separate drain line 833, vacuum Room SR51 enters recovery pipe 835, and then is discharged in waste liquid barrel.6th Magneto separate control valve V836 turns off vacuum chamber While SR51 is with recovery pipe 835, the second Magneto separate detergent line of connection 836 and recovery pipe 835, at this point, Magneto separate is wiped Cleaning waste liquid in son 44 enters recovery pipe 835 through the second Magneto separate detergent line 836, and then is discharged in waste liquid barrel.
Optionally, when the quantity of the quantity of cleaning solution injecting mechanism 42 and cleaning solution output mechanism 43 is at least two When, Magneto separate fluid injection pipeline 832, Magneto separate drain line 833, the first Magneto separate detergent line 834, the second Magneto separate cleaning pipe Road 836, the second Magneto separate control valve V832, third Magneto separate control valve V833, the 4th Magneto separate control valve V834 and the 5th magnetic The quantity of separate control valve V835 is consistent with the quantity of cleaning solution injecting mechanism 42.That is, setting at least two is in parallel The first Magneto separate detergent line 834 being arranged, the second Magneto separate detergent line 836 that setting at least two is arranged in parallel, setting At least two at least two Magneto separate fluid injection pipelines 832 being arranged in parallel, at least two magnetic that setting at least two is arranged in parallel Separating liquor drainage pipeline 833, the setting of valve are adapted with its pipeline.Can be realized in this way to the determinand in reaction vessel carry out to It is few to clean twice, it avoids impurity from remaining in determinand, guarantees the purity of determinand, improve the reliability of pattern detection.
Moreover, can be realized and pass through by multiple valves and Magneto separate fluid injection pipeline 832, the first Magneto separate detergent line 834 Injection and realization cleaning function of one Magneto separate syringe to cleaning solution, can achieve the purpose that save cost.It also adopts simultaneously The control that each cleaning solution injecting mechanism 42 is realized with the same power source, that is, Magneto separate syringe SR4 is using the same power source Magneto separate driving source SR5 realizes the control of each cleaning solution output mechanism 43.Also, each cleaning solution output mechanism 43 is equipped with Magneto separate swab 44 can be the drain needle in each cleaning solution output mechanism 43 and be not necessarily to be moved horizontally to additional cleaning position, The maintenance to drain needle can be completed, not only simplify the mechanical structure of Magneto separate cleaning assembly 4, but also save magnetic point in test process From time to accelerating flux.
Magneto separate cleaning liquid channel system 83 further includes the 7th Magneto separate control valve V837, and the 7th Magneto separate control valve V837 is set It is placed on Magneto separate imbibition pipeline 831, for drawing the cleaning solution at least two soda liquor containers.Dispense liquid channel system 81 also Including the 4th dispensing control valve V814, the 4th dispensing control valve V814 is set in the second dispensing detergent line 813, for drawing Cleaning solution at least two soda liquor containers.It is understood that the quantity of the soda liquor container of storage cleaning solution can be Two.Two cleaning solutions are drawn branch pipe and are connect by the 7th Magneto separate control valve V837 with Magneto separate imbibition pipeline 831, and two clear The other end that washing lotion draws branch pipe is respectively protruding into soda liquor container.7th Magneto separate control valve V837 is being connected to one of them While cleaning solution draws branch pipe and Magneto separate imbibition pipeline 831, turns off another cleaning solution and draw branch pipe and Magneto separate pipette Road 831.Two dispensings absorption branch pipes pass through the 4th Magneto separate control valve V834 respectively and connect with the second dispensing detergent line 813, The other end that two dispensings draw branch pipe is respectively protruding into soda liquor container.4th Magneto separate control valve V834 is being connected to wherein While one dispensing draws branch pipe and the second dispensing detergent line 813, turns off another dispensing absorption branch pipe and the second dispensing is clear Wash pipeline 813.In this way, the cleaning solution in one of soda liquor container has used, another soda liquor container can also continue to mention For cleaning solution, in this way, Full-automatic chemiluminescence immunoassay analysis meter can operate normally into soda liquor container when additional clean liquid Without shutting down, treatment effeciency is improved.Preferably, also setting up cleaning solution detection part 88 below the front left side of carrying platform, use Cleaning solution surplus in detection soda liquor container, facilitates monitoring, so that user adds cleaning solution in time.
Optionally, fluid path component 8 further includes condensed water discharge pipe road, and condensed water discharge pipe road connects the control of the 5th Magneto separate The drainage channel 1212 of valve V835 and reagent pot 121.5th Magneto separate control valve V835 turns off the second Magneto separate detergent line 836 and Magneto separate driving source SR5, communicated drainage channel 1212 and Magneto separate driving source SR5, for being discharged in reagent pot 121 Condensed water.That is, the condensed water in reagent pot 121 can also be discharged in fluid path component 8, condensed water is avoided to accumulate in reagent pot Existing electrical safety potential problem in 121.5th Magneto separate control valve V835 controls 836 row of the second Magneto separate detergent line It also can control the discharge of condensed water in reagent pot 121 while cleaning waste liquid out.When condensed water is discharged, the 5th Magneto separate control valve V835 is connected to condensed water discharge pipe road and the second vacuum pump SR55, turns off the second Magneto separate detergent line 836 and the second vacuum pump SR55, the condensed water in reagent pot 121 is entered in condensed water discharge pipe road by drainage channel 1212, and then passes through the second vacuum Pump SR55 is discharged in waste liquid barrel.Discharge cleaning waste liquid when, the 5th Magneto separate control valve V835 turn off condensed water discharge pipe road with Second vacuum pump SR55 is connected to the second Magneto separate detergent line 836 and the second vacuum pump SR55, cleans waste liquid through the second Magneto separate Detergent line 836 is discharged in waste liquid barrel by the second vacuum pump SR55.
Again optionally, fluid path component 8 further includes being incubated for waste liquid discharge line and being incubated for waste liquid control valve, is incubated for waste liquid discharge Piping connection removal waste fluid component 7 and Magneto separate driving source SR5 are incubated for waste liquid control valve and are set on incubation waste liquid discharge line, For controlling the on-off for being incubated for waste liquid discharge line, it is discharged in waste liquid barrel with will test the waste liquid in rear reaction vessel.Also It is to say, the waste liquid after reaction vessel detection can also be discharged in fluid path component 8.Be incubated for waste liquid discharge line connection removal waste fluid component 7 with Vacuum chamber SR51, when incubation waste liquid control valve control incubation waste liquid discharge line is access, removal waste fluid component 7 will be to removal waste fluid Waste liquid in reaction vessel, which is transported to, is incubated for waste liquid discharge line, and is discharged to waste liquid barrel through vacuum chamber SR51, recovery pipe 835 In.After waste liquid discharge, it is incubated for waste liquid control valve breakdown and is incubated for waste liquid discharge line.
Moreover, fluid path component 8 further includes flushing pipeline and washing control valve, flushing pipeline connects third Magneto separate control valve V833 and vacuum chamber SR51, washing control valve is set in flushing pipeline, for controlling the on-off of flushing pipeline.When flushing, punching Washing control valve makes flushing pipeline access, the cleaning being discharged through the first dispensing drain line 814 and the second dispensing drain line 815 Waste liquid can enter vacuum chamber SR51 through flushing pipeline, to clean to vacuum chamber SR51.This is because carrying out the detection that shines Waste liquid afterwards is messy, by the cleanliness that can be improved vacuum chamber SR51 after cleaning waste-liquid cleaning.Certainly, in the utility model Other embodiments in, other flushing mechanisms can also be introduced, vacuum chamber SR51 is cleaned.If rinsing control without rinsing Valve breakdown flushing pipeline processed.
When cleaning waste liquid is discharged in one of Magneto separate drain line 833, corresponding valve is opened thereon, and its residual magnetism Valve on separating liquor drainage pipeline 833 is closed, in order to avoid vacuum chamber SR51 aspirates air, vacuum chamber SR51 is accurately inhaled Take the cleaning waste liquid in reaction vessel;Also, in the cleaning waste liquid being discharged in reaction vessel, it is also corresponding to be incubated for waste liquid control valve Closing.When be discharged reaction vessel in detection waste liquid when, be incubated for waste liquid control valve open, Magneto separate drain line 833 and its On valve close, guarantee detection waste liquid be smoothly discharged.It is understood that each valve of night road component 8 passes through main control Component 77 carries out automatically controlling.
Fluid path component 8 is cooperated by the switch of the design of piping connection and valve, with a small amount of control device realize it is complete from The detection of dynamic chemical illumination immunity analysis instrument, maintenance process have reached great to function required by gas-liquid road in cost Reduce, while but also complete machine can to avoid number of devices and volume restriction and obtain more preferably integrated with miniaturization.And And separate injection needle swab 34 with so that testing process can permit the sample-adding reagent adding of separate injection needle 31 during need not be cleaned The fixation position in pond 35 limits, and improves test flux.The vacuum chamber SR51 negative pressure source of Magneto separate cleaning system replaces wriggling Pump, realizes volume, cost, innovation and advantage in ease for maintenance;In addition Magneto separate swab 44 allows complete machine to increase without additional Add moving component and realize the cleaning to drain needle, eliminates the threat for carrying pollution to be realized with a low cost.
Optionally, the sample loader mechanism 11 of sample reagent loading assembly 1 further includes the dispensing for cleaning dispensing component 3 The needle cleaning structure 114 of needle 31, needle cleaning structure 114 are set on chassis 112, and be located at two adjacent sample racks 111 it Between.That is, needle cleaning structure 114 is integrated on sample loader mechanism 11, rather than chemiluminescent analyzer is set In other structures, the overall dimensions of chemiluminescent analyzer can be reduced in this way.Also, needle cleaning structure 114 is arranged in sample On loader mechanism 11, moreover it is possible to reduce the motion path of separate injection needle 31, improve sample process efficiency.This is because 31 turns of separate injection needle It moves after sample or reagent, is cleaned, avoid generating cross contamination when transfer sample next time or reagent.Separate injection needle 31 It after shifting sample or reagent, returns and is directly cleaned at sample loader mechanism 11, reduce separate injection needle 31 and move to other positions The path that cleaning returns sample loader mechanism 11 or load reagents mechanism 12 is set, improves the transfer efficiency of separate injection needle 31, in turn Improve the efficiency of complete machine.Moreover, needle cleaning structure 114 can be service sink, the bottom of service sink accesses fluid path pipeline, passes through liquid Road pipeline cleaning solution and discharge cleaning waste liquid.Certainly, needle cleaning structure 114 may be that other can carry cleaning solution Structure, such as bottle.Moreover, needle cleaning structure 1141 can also by fluid path pipeline strengthen cleaning solution, to separate injection needle into Row strengthens cleaning, guarantees cleaning effect.
Referring to Fig. 3 to Fig. 6, it is to be understood that due to being had differences between each sample, the detection to be carried out there is also Difference, so sample reagent loading assembly 1 can be used for position and detection project, the position of identification agent and the kind of identification sample Class.Specifically, being respectively provided with identification code on the outside of the outside of sample container and reagent container, sample reagent loading assembly 1 can be swept The identification code of each sample container is retouched, for identification the position of sample and project to be detected;Sample reagent loading assembly 1 can also The identification code of each reagent container is scanned, for identification the position of reagent and type.It can be avoided the detection for carrying out mistake in this way The problems such as project or addition sample reagent mistake etc., guarantee that pattern detection is gone on smoothly.It is understood that identification code can be Bar code, two dimensional code or other types are convenient for the information of identification.
Specifically, sample reagent loading assembly 1 further includes the identification code scanner 13 for scanning recognition code, sample is loaded Scanning notch 1111 is provided in mechanism 11.Identify that code scanner 13 being capable of sample container on scanned samples loader mechanism 11 Identification code, identification code scanner 13 can also scan the identification code of reagent container in load reagents mechanism 12 through scanning notch 1111. Identification code scanner 13 is for scanning and identifying the identification code of sample container and the identification code of reagent container.Main control component 77 with Identify that code scanner 13 is electrically connected, main control component is scanned operation for controlling identification code scanner 13, and stores identification The every terms of information that the scanning of code scanner 13 obtains, such as position and the project information to be detected of sample, position and kind such as reagent The information such as class.Before Full-automatic chemiluminescence immunoassay analysis meter detects sample, the first scanned samples of identification code scanner 13 The identification code of each sample container in loader mechanism 11 scans the identification code of each reagent container in load reagents mechanism 12.It can With understanding, identifies that 13 scanned samples identification code of code scanner and reagent identification code do not have sequencing, can first scan sample This identification code, can also first identification agent identification code, this is to the no materially affect of the detection of sample.Certainly, in the utility model Other embodiments in, can also during pattern detection to the identification code of the identification code of sample container and reagent container into Row scanning.
Identification code scanner 13 is located at the outside of sample reagent loading assembly 1.The sample loader mechanism 11 of annular is by space It is divided into interior outside, inside refers to the space where load reagents mechanism, correspondingly, another space is the outer of sample loader mechanism Side.Identify code scanner 13 can specimen discerning code directly on scanned samples loader mechanisms, but sample reagent loader mechanism set Set on the outside of load reagents mechanism, sample loader mechanism can block load reagents mechanism, be unfavorable for reagent container identification code Scanning.Therefore, scanning notch 1111 is provided on sample loader mechanism.Scanning notch 1111 is that identification code scans for convenience Instrument 13 scans the identification code of the reagent container into the load reagents mechanism on the inside of sample loader mechanism by the scanning notch 1111. Specifically, identification code scanner 13 can on scanned samples loader mechanism sample container identification code, identification code scanner 13 is also The identification code of reagent container in load reagents mechanism 2 can be scanned through scanning notch 1111.
Identify that code scanner 13 can be passed sample essential information such as position, project information to be detected and user are basic etc. It is defeated by main control component, moreover, sample is during the treatment, the sample real-time tracking that main control component is detected works as sample After this detection that shine, main control component, which obtains to be incubated for, surveys the sample parameter that detects of light step, and by the sample parameter with Sample essential information is corresponding, so that sample and its detection parameters correspond, avoids malfunctioning.In the present embodiment, sample container Loading is carried out by manual type, and when loading, the identification code of sample container is placed outwardly, facilitates identification code scanner 13 Scanning.Certainly, when it is automatic load conveying sample container when, if the identification code of sample container not outwardly, may also set up rotational structure Carry out rotated sample container, so that the identification code of sample container is outwardly.
The sample reagent loading assembly of the Full-automatic chemiluminescence immunoassay analysis meter of the utility model uses sample loading machine Structure is set in the outboard structure of load reagents mechanism, and cooperates identification code scanner 13, and sample loader mechanism drives sample therein When this container rotates, the identification code of 13 scanned samples container of code scanner is identified, the scanning notch 1111 of sample loader mechanism is right When should identify code scanner 13, load reagents mechanism drives reagent container rotation therein, and identification code scanner 13 passes through scanning Notch 1111 scans the identification code of reagent container, i.e., by same identification code scanner 13 realize sample container identification code and The scanning of the identification code of reagent container, effective solution pass through at present two identification code scanners 13 scan caused by it is at high cost with And the problem that occupied space is big, to reduce production cost, and reduce occupied space, so that sample reagent loads the ruler of scanning system It is very little small, and then reduce the package size of chemiluminescent analyzer.
Preferably, identification code scanner 13 is fixedly installed on the outside of sample loader mechanism 11.Chemistry can be facilitated in this way Luminescence analyzer determines the location information of each sample container Yu each reagent container.Sample loader mechanism 11 drives sample container It successively turns at identification code scanner 13 and is scanned;Scan the corresponding identification code scanner 13 of notch 1111, load reagents machine Structure 12 drives reagent container successively to turn at scanning notch 1111 and is scanned.Specifically, identification code scanner 13 is fixed Afterwards, identification code scanner 13 has a scanning area, which can project sample loader mechanism 11 and reagent dress On mounted mechanism 12.When scanned samples container identifier, sample loader mechanism 11 drives each sample container rotation thereon, makes The scanning area that sample container passes sequentially through identification code scanner 13 is obtained, in this way, identification code scanner 13 successively records sample appearance The information of device realizes the scanning of sample container identification code.When scanning reagent container identification code, first sweeping sample loader mechanism The alignment identification code scanner 13 of notch 1111 is retouched, identification code scanner 13 is enabled to correspond to load reagents mechanism 12 by notch In reagent container, then, load reagents mechanism 12 drive thereon each reagent container rotation so that reagent container successively leads to The scanning area of identification code scanner 13 is crossed, in this way, identification code scanner 13 successively records the information of sample container, realizes reagent The scanning of container identifier.Certainly, in the other embodiments of the utility model, identify that code scanner 13 is also possible to on-fixed , as long as identification code scanner 13 can be directed at scanning notch 1111 and the scanning of reagent container identification code can be realized.
Further, there is default spacing between two adjacent sample racks and scan notch 1111 to be formed, on reagent pot With scanning window 1211, scanning window 1211, scanning notch 1111 and identification code scanner 13 are corresponded to each other, reagent disc 122 It drives multiple reagent containers to rotate, moves to reagent container successively at scanning window 1211, the identification scanning examination of code scanner 13 The identification code of agent container.
It is understood that between two adjacent sample racks 111 overlap after, between adjacent sample rack 111 exist compared with Big space can scan the identification code of reagent container in load reagents mechanism 12 by the space.Certainly, adjacent sample rack 1111 can separately be supported by support column, also can guarantee between adjacent sample rack 1111 there is scanning notch 1111.Preferably Ground, in the present embodiment, the quantity of scanning notch 1111 are one, i.e., knowledge of one of scanning notch 1111 to reagent container Other code is identified, thus can satisfy scanning demand, while can also make the compact-sized of sample rack, as much as possible to hold Sample container is carried, frequent additional sample container is avoided.It certainly, can also any phase in the other embodiments of the utility model Just setting scans notch 1111 between two adjacent sample racks 111, alternatively, wherein between several two adjacent sample racks 111 Setting scanning notch 1111, in this way, also can satisfy scanning demand.
In the present embodiment, there is scanning window 1211 on reagent pot 121.That is, identification code scanner 13 passes through Scanning window 1211 scans the identification code of reagent container in reagent pot 121.It can be avoided cooling capacity loss in this way, be easy to keep reagent Low temperature environment in pot 121.When scanning reagent container identification code, scanning window 1211, scanning notch 1111, identification code scanning Instrument 13 corresponds to each other, and reagent disc 122 drives multiple reagent containers to rotate, and reagent container is driven successively to move to scanning window At 1211, identification code scanner 13 scans the identification code of reagent container.
It should be noted that since there are gaps between adjacent sample container, in order to avoid identification code scanner 13 is logical It crosses the gap scanning and first controls reagent before scanned samples container identifier to the reagent container identification code in reagent pot 121 Disk 122 rotates, so that the space between adjacent reagent container corresponds to scanning window 1211, is being scanned sample container in this way When identification code, identification code scanner 13 is aligned always between the scanning window 1211 and adjacent two reagent container of reagent pot 121 Space, when sample loader mechanism 11 drives sample container rotation, sample container passes sequentially through identification code scanner 13 and is scanned, Even if the gap alignment between adjacent sample container identifies code scanner 13, due to being corresponding two reagents at scanning window 1211 Space between container, the scanning that identification code scanner 13 will not be wrong guarantee scanning result to the identification code of reagent container Accuracy.Optionally, the spacing between adjacent sample container is minimized, is held in this way, the spacing is unable to complete scan to reagent The identification code of device avoids generating interference to sample bar code, while can also increase the capacity of sample container as far as possible.
Further, there is transparency window 1213, transparency window 1213 is installed at scanning window 1211, thoroughly on reagent pot 121 Bright window 1213 is corresponding with identification code scanner 13, and in 111 rotation process of sample rack, identification code scanner 13 is by presetting spacing The identification code of reagent container in reagent disc is scanned through transparency window 1213.Preferably, reagent pot 121 is fixed setting, so that thoroughly Bright window 1213 remains static with identification code scanner 13.Transparency window 1213 can will be isolated inside and outside reagent pot 121, avoid trying Cooling capacity in agent pot 121 is lost.Transparency window 1213 corresponds to the identification code of reagent container on reagent disc 122 in reagent pot 121, this Sample, identification code scanner 13 scan the identification code of reagent container on reagent disc 121 by prepsetting gap and transparency window 1213.It is optional Ground, transparency window 1213 can be transparent glass, can also be by there is other transparent materials to be made.
Referring to Fig. 3 to Fig. 7, as an embodiment, load reagents mechanism 12 further includes refrigeration structure 127, refrigeration Structure 127 is used to, so that being in low temperature environment in reagent pot 121, be convenient for reagent preservation to freezing in reagent pot 121.Show Example, the bottom of reagent pot 121 has installation position, and refrigeration structure 127 is installed in installation position.Due to the body of refrigeration structure 127 Product is small, can be not take up central area, can reduce the diameter dimension for the shaft that driving reagent disc 122 rotates in this way, and reduction is walked Line improves the operational efficiency of driving reagent disc 122;Meanwhile refrigeration structure 127 will not also drive with reagent disc 122 and its transmission It is interfered between component.Since refrigeration structure 127 is not take up the central area of reagent pot 122, use can be stored in reagent pot 122 The structure of wherein reagent, in the case where being placed with identical quantity reagent container, reagent pot 121 are mixed in driving reagent container Radius reduces, and volume and surface area also greatly reduce, and under identical external environment, reagent pot 121 is caused by surface heat transfer Heat exchange amount greatly reduce, therefore, power needed for refrigeration structure 127 reduce, the volume of refrigeration structure 127 is subtracted It is small.
Specifically, refrigeration structure 127 includes refrigeration part, refrigeration part is located at the lower section of reagent disc 122, and deviates reagent The center of pot 121, for freezing in reagent pot 121.Specifically, refrigeration part have cold end and hot end, refrigeration part it is cold End is set to 122 lower section of reagent disc, and for freezing to reagent disc 122, the hot end of refrigeration part is set at transparency window 1213.System After cold part is powered, cold end can generate cooling capacity, to freeze to reagent disc 122, and then realize to the reagent system in reagent container It is cold;Due to requiring refrigeration in reagent pot 121 to guarantee that reagent stores, and outside reagent pot then it is room temperature space, this will lead to Condensed water is generated on bright window 1213 and influences to identify the scanning of code scanner 13, and the heat that the hot end of refrigeration part generates is transmitted After on to transparency window 1213, it can be realized and transparency window 1213 and reagent pot outer contacting part are heated, avoid on transparency window 1213 Condensed water.
Optionally, refrigeration structure 127 further includes cold end vaporizer, and cold end vaporizer is set in reagent pot 121, for adding Quickly cooling amount distributes, and guarantees that cooling capacity is uniformly distributed in reagent pot 121, guarantees refrigeration effect.Moreover, cold end vaporizer is also located at examination The lower section of agent disk 122 can be avoided the space that refrigeration structure 127 occupies reagent container in this way, guarantee to carry examination on reagent disc 122 The quantity of agent container.Exemplary, cold end vaporizer can be cold end fan and/or cold end fin etc..
Again optionally, load reagents mechanism 12 further includes hot-side heat dissipation device 128 and conducting-heat elements 1281.Hot-side heat dissipation device 128 connect with the hot end of refrigeration part, and are located at the outside of reagent pot 121.Due to the eccentric setting of refrigeration structure 127, refrigeration It the hot end of component can be close to the inner wall of reagent pot 121, in this way, wind can be shortened when drawing the heat in hot end by air duct Road, so that the structure in air duct is simple, and to the air quantity of hot-side heat dissipation device 128-grace performance requirement not good heat dissipation effect.It can manage Solution, the hot end of refrigeration part can be transferred heat on hot-side heat dissipation device 128 by heat-conducting plate.Conducting-heat elements 1281 with Hot-side heat dissipation device 128 connects and corresponds to the outside of scanning window 1211.I.e. conducting-heat elements 1281 connect hot-side heat dissipation device 128 with The outside of transparency window 1213 avoids heat losses to transfer heat at transparency window 1213.Conducting-heat elements 1281 are provided to realize The defrosting function of transparency window 1213 has the characteristics that energy conservation and environmental protection structure is simple.It is understood that the outside of transparency window 1213 It is in reagent pot as between sample loader mechanism 11 and load reagents mechanism 12, in transparency window 1213.Exemplary, hot end dissipates Hot device 128 can be hot end fan and/or hot-side heat dissipation piece etc..Conducting-heat elements 1281 are made from a material that be thermally conductive.In this implementation Example in, hot-side heat dissipation device 128 include hot end fan 1283 and hot-side heat dissipation piece 1282 so that heat can directed flow, add Speed heat amount distributes.
Optionally, the bottom of reagent pot 121 is provided with drainage channel 1212, and drainage channel 1212 is for being discharged refrigeration structure 127 condensed waters generated, drainage channel 1212 can also be discharged the condensed water of other components of load reagents mechanism 12 generation, keep away Exempt from condensed water to gather in reagent pot 121 and influence electrical safety.
In addition, being connected in reagent pot 121 and outside reagent pot 121 due to inhaling reagent wells 1231, reagent pot referring to Fig. 3 to Fig. 8 There is in 121 for poly- source the cold environment of cold air, be the external environment of room temperature outside reagent pot 121, can inhale at reagent wells 1231 Condensed water is generated, condensed water can have the possibility flowed in reagent container, influence the accuracy of pattern detection.Therefore, this is practical The reagent pot cover 123 of novel load reagents mechanism 12 further includes condensation structure 125, and condensation structure 125 is set to reagent pot cover On 123, inhale reagent wells 1231 be located on condensation structure 125, condensation structure 125 be used for pick up inhale reagent wells 1231 at generation it is cold Condensate.Condensation structure 125 picks up the condensed water inhaled at reagent wells 1231, and condensing drip is avoided to fall in reagent container, simultaneously also It is avoided that cooling capacity is largely lost, reduces energy consumption.
Further, condensation structure 125 includes the cold plate 1251 and drip tray 1252 that are oppositely arranged, and cold plate 1251 In drip tray 1252 top and enclose and be set as airflow channel, be connected in the airflow channel and reagent pot 121, i.e., in reagent pot 121 Cold air be able to enter airflow channel.Moreover, cold plate 1251 is detachably connected with drip tray 1252.It is understood that Between cold plate 1251 and drip tray 1252 connection can be connected and fixed by connector such as screw etc., at this time cold plate 1251 There are gaps at the edge of edge and drip tray 1252;Certainly, it can also be set respectively in drip tray 1252 and the edge of cold plate 1251 Mounting plate is set, also to guarantee that there is also gaps for two opposite mounting plates;Guarantee that condensation space is connected to reagent pot 121.Meanwhile It can also be between cold plate 1251 and drip tray 1252 except between airflow and the space of water receiving, filling thermal insulation material is avoided Cooling capacity is lost in reagent pot 121.
Inhaling reagent wells 1231 includes that first on cold plate 1251 inhales reagent wells 12311 and be located on drip tray 1252 Second inhale reagent wells 12312.First suction reagent wells 12311 are oppositely arranged with the second suction reagent wells 12312, and, first inhales examination The profile of the second suction reagent wells 12312 can be completely covered in the profile in agent hole 12311.That is, first inhales reagent wells 12311 The second suction reagent wells 12312 can be completely covered in projection on drip tray 1252.In the present embodiment, first inhales reagent wells 12311 and second suction reagent wells 12312 be circle, the first aperture for inhaling reagent wells 12311 is greater than second and inhales reagent wells 12312 Aperture;Certainly, in the other embodiments of the utility model, first, which inhales reagent wells 12311 and second, inhales reagent wells 12312 It also may respectively be other shapes.First suction reagent wells 12311 are connected to external environment, and second inhales reagent wells 12312 can be with examination Connection in agent pot 121 facilitates separate injection needle 31 to protrude into and draws reagent in reagent pot 121.Moreover, gear is arranged in the edge of drip tray 1252 Plate, baffle are that the condensed water on drip tray 1252 is flowed out from the edge of drip tray 1252 in order to prevent.
After condensation structure 125 is mounted on reagent pot cover 123, the cold air of the flowing in reagent pot 121 will pass through The edge of cold plate 1251 and drip tray 1252 enters airflow channel, and the normal temperature air in external environment by first by that can inhale Reagent wells 12311 enter airflow channel, can condense generation condensed water at the edge of the first suction reagent wells 12311, at this time condensed water It can be dropped on drip tray 1252, enter in reagent pot 121 without inhaling reagent wells 12312 through second.
Further, the hole wall of the first suction reagent wells 12311 extends to form first annular barrel towards drip tray 1252 1253, the inner wall of first annular barrel 1253 is contacted by the first suction reagent wells 12311 with external environment, first annular barrel 1253 outside wall surface is contacted with airflow channel local environment.First annular barrel 1253 can be provide with the second suction reagent wells 12312, and first annular barrel 1253 is located in airflow channel.Reagent wells 12311 are inhaled in the first annular connection of barrel 1,253 first Reagent wells 12312 are inhaled with second, when separate injection needle 31 draws reagent, separate injection needle 31 can pass through first and inhale the entrance of reagent wells 12311 First annular barrel 1253, and inhale reagent wells 12312 through second and enter reagent pot 121, it draws in reagent pot 121 in reagent container Reagent.
It is the space of cold environment in reagent pot 121, is normal temperature environment outside reagent pot 121.When condensation structure 125 is mounted on examination After on agent pot cover 123, the cold air of the flowing in reagent pot 121 will by the edge of cold plate 1251 and drip tray 1252 into Enter airflow channel, cold air can be condensate on first annular barrel 1253, and first annular 1253 temperature of barrel is caused to reduce.When Outside air forms condensation process, condensed water collects on first annular barrel 1253 after the first suction entrance of reagent wells 12311 Knot, is finally dropped on drip tray 1252.It, can be from first annular barrel after outside air reaches first annular 1253 end of barrel 1253 and second enter in condensation channel and blend with cold air between suction reagent wells 12312, largely will not be from drip tray The second of 1252 inhales reagent wells 12312 and flows into, to not have condensation in the second suction reagent wells 12312 of drip tray 1252 Water.It can be avoided the condensed water generated at the first suction reagent wells 12311 in this way to enter in reagent container.
Moreover, first annular barrel 1253 can be completely covered second far from one end profile of the first suction reagent wells 12311 Inhale the profile of reagent wells 12312.In the present embodiment, the one end of first annular barrel 1253 far from the first suction reagent wells 12311 Aperture is greater than the second aperture for inhaling reagent wells 12312.That is, first annular 1253 end of barrel is on drip tray 1252 The diameter of projection is greater than the second diameter for inhaling reagent wells 12312.First annular barrel 1253 is used as external environment and airflow channel One interface of local environment (low temperature environment in reagent pot 121), effectively increases external environment and airflow channel institute The contact for locating environment, so that condensed water is easy to condense on first annular barrel 1253, and can be along first annular barrel 1253 It flows down and drops onto water receiving version 1252, without entering in the second suction reagent wells 12312.
Still further, the hole wall of the second suction reagent wells 12312 extends to form the second annular tube wall towards cold plate 1251 1254.Second annular tube wall 1254 is corresponding with first annular barrel 1253, and water blocking flange 1254 is for stopping drip tray 1252 On condensed water, avoid condensed water by second suction reagent wells 12312 enter in reagent pot 121.Preferably, the second annular canister Wall 1254 inhales reagent wells 12312 towards the direction of cold plate 1251 in shrink mouth shape by second, that is to say, that the second annular tube wall 1254 aperture is less than the aperture of first annular barrel 1253.It is understood that the opening of the second annular tube wall 1254 is straight Diameter is less than the diameter of first annular 1253 end of barrel, in this way, the condensed water on first annular barrel 1253 can flow to second The outside of annular tube wall 1254 avoids in condensation flow to reagent pot 121.Moreover, there is drainage hole on drip tray 1252, draining Hole is connected to drainage channel 1212.Drainage hole is used to drain the condensed water on drip tray 1252, avoids condensed water from water blocking flange 1254 overflow into reagent pot.Condensed water on drip tray 1252 can be entered in drainage channel 1212 with drainage hole, through draining Reagent pot 121 is discharged in channel 1212.It is understood that can by pipeline communicated drainage hole and drainage channel 1212, or Setting draining flow guiding structure, splashing when avoiding water drainage condensed water.
Referring to Fig. 1, Figure 12, Figure 13 and Figure 15, as an embodiment, Magneto separate adsorbing mechanism 48 is set to magnetic point From in pedestal 41, and it is located at the two sides of reaction vessel rotation path.Magneto separate adsorbing mechanism 48 can be by the magnetic in reaction vessel Pearl is adsorbed on the side wall of reaction vessel, realizes the cleaning of determinand and impurity in reaction vessel.Specifically, Magneto separate adsorption machine During adsorbing magnetic bead, magnetic bead is able to drive determinand and is adsorbed on the side wall of reaction vessel structure 48, at this point, impurity dissolves In cleaning solution, waste liquid is discharged by cleaning solution output mechanism 43.It is understood that being grasped by separation cleaning at least once Work cleans the determinand in reaction vessel with impurity, guarantees the purity of determinand, and then guarantee pattern detection result Accuracy.
Optionally, Magneto separate adsorbing mechanism 48 includes multiple adsorption pieces, and multiple adsorption pieces are alternately disposed at reaction vessel fortune The interior outside of dynamic rail mark, i.e., one of adsorption piece are located at the outside of reaction vessel motion profile, two adjacent adsorption piece positions In the inside of reaction vessel motion profile.It can be realized the magnetic bead in reaction vessel in this way and be successively adsorbed in two opposite side walls On, i.e., magnetic bead is mobile in two opposite sides of reaction vessel inner wall.Both it had realized in separation process and magnetic particle absorption had been gathered Collection, also reaches in cleaning process and magnetic particle is allowed to disperse, so that magnetic bead is sufficiently contacted with cleaning solution in the process of movement reaches clear The purpose washed, it is effective to clean after magnetic bead accumulation in internal remaining impurity such as enzyme etc., reduce the additional knots such as mechanism mixing Structure breaks up the effect of the magnetic bead of accumulation, reduces cost.Moreover, adsorption piece is installed from the bottom of Magneto separate pedestal 41, it can be maximum to the greatest extent The side wall close to reaction vessel of limit, increases the adsorption capacity of magnetic bead, reduces the loss late of magnetic bead.Exemplary, adsorption piece can be with For magnet, such as permanent magnet, electromagnet.
Further, Magneto separate adsorbing mechanism 48 includes the first magnetic part 481 and the second magnetic part 482.It is exemplary, first Magnetic part 481 and the second magnetic part 482 are magnet.That is the first magnetic part 481 is the first magnet, and the second magnetic part 482 is the Two magnet.First magnetic part 481 and the second magnetic part 482 are distributed along the side of Magneto separate pedestal 41, and the first magnetic part 481 It is located at the two sides of reaction vessel rotation path with the second magnetic part 482.Moreover, the first magnetic part 481 and the second magnetic part 482 It is arranged in the bottom that the position of Magneto separate pedestal 41 corresponds to reaction vessel, the distribution mode after expansion is as shown in figure 15.
Magneto separate pedestal 41 has the first cleaning position 414 between cleaning solution inlet opening 412 and cleaning solution drainage hole 413, Corresponding first cleaning position 414 setting of first magnetic part 481, corresponding second cleaning position 415 setting of the second magnetic part 482.Vertical On line direction, the magnetic pole line of the first magnet 481 and the angle of vertical line are the first angle, the magnetic pole line of the second magnet 482 Angle with vertical line direction is the second angle, wherein the first angle is different with the second angle.That is, the first magnetic part 481 and second magnetic part 482 be divided into inside and outside reaction vessel rotation path, and the magnetic pole line of the first magnetic part 481 There is dislocation on the axial direction of Magneto separate pedestal 41 with the magnetic pole line of the second magnetic part 482 is antarafacial setting.Magneto separate When pedestal 41 drives reaction vessel to be moved at the second magnetic part 482 from the first magnetic part 481, the first magnetic of antarafacial setting Property part 481 and the second magnetic part 482 magnetic particle can be adsorbed to the second magnetic part by the side where the first magnetic part 481 Assemble magnetic particle during side where 482, i.e., the opposite other side is moved to from side, in such manner, it is possible to accelerate magnetic micro- The adsorption rate of grain ensure that detection in performance of both cleaning-separation, guarantees sample inspection so that magnetic reservation is more efficient It is accurate to survey result, while cleaning speed can also be improved, and then improves the speed of service of complete machine.It is understood that magnetic pole line Refer to the line of the pole N and the pole S or the line of the pole S and the pole N.Wherein, the stain of Figure 13 indicates the magnetic bead of aggregation, larger diameter The round transhipment path for indicating reaction vessel.
It is understood that the first magnetic part 481 is not provided at cleaning solution inlet opening 412, this is because in cleaning solution The step of addition cleaning solution is executed at inlet opening 412, magnetic particle can scatter, and come into full contact with and cleaned with cleaning solution. If just being adsorbed at this time using the first magnetic part 481, it will lead on the first magnetic part 481 directly absorption magnetic particle to side wall, influence Cleaning effect.It is when cleaning waste liquid to avoid being discharged, by magnetic particle that the second magnetic part 482 is arranged at cleaning solution drainage hole 413 Also it is discharged together, while being also avoided that magnetic particle damages.Therefore, corresponding first cleaning position 414 setting of the first magnetic part 481, the The corresponding cleaning solution drainage hole 413 of two magnetic parts 482 is arranged.
Moreover, Magneto separate pedestal 41 has rotary shaft, Magneto separate pedestal 41 drives reaction vessel to rotate around rotary shaft, i.e. magnetic Separating support drives reaction vessel drive sequentially to rotate around rotary shaft, and sequentially through manhole appendix 411, cleaning solution inlet opening 412 With cleaning solution drainage hole 413 etc..Still further, rotary shaft is vertical line direction, the magnetic pole line of the first magnetic part 481 with Straight line intersection where the extending direction of rotary shaft.That is, the magnetic pole line of the first magnetic part 481 is along Magneto separate pedestal 41 radial directions, and can be different with the angle of rotary shaft.Preferably, the magnetic pole line of the first magnetic part 481 and The magnetic pole line of two magnetic parts 482 is vertical.That is, the placement location principle of the first magnetic part 481 and the second magnetic part 482 It is upper unrestricted, as long as it is perpendicular to can satisfy the two magnetic pole line.In this way, the first magnetic part 481 and the second magnetic part 482 magnetive attraction can mutually stagger, so that magnetic particle is assembled rapidly in corresponding vertical direction, acceleration is adsorbed onto opposite side Process avoids that magnetic particle being sucked out when discharge cleaning waste liquid.
Specifically, the magnetic pole line of the first magnetic part 481 is vertical with vertical line direction, the magnetic pole of the second magnetic part 482 connects Line is vertical with vertical line direction, i.e., the magnetic pole line of the first magnetic part 481 extends along the radial direction of Magneto separate pedestal 41, and second The magnetic pole line of magnetic part 482 extends along the axial direction of Magneto separate pedestal 41.That is, the magnetic pole of the first magnetic part 481 Line is parallel to the cross section of reaction vessel, the magnetic pole line of the second magnetic part 482 exists perpendicular to the cross section of reaction vessel The first magnetic part 481 on the inside of reaction vessel motion profile is radially placed across on the outside of reaction vessel motion profile Second magnetic part 482 is vertically placed.In this way, magnetic particle can be adsorbed to reaction vessel side wall primary for the first magnetic part 481, It is micro- that second magnetic part 482 can assemble in the perpendicular direction magnetic during absorption magnetic particle side wall another to reaction vessel Grain, to reduce the retention rate after magnetic particle cleaning, guarantees detection performance, while can also in addition accelerating the process for being adsorbed onto opposite side Cleaning speed is improved, and then improves the speed of service of complete machine.Certainly, in the other embodiments of the utility model, the first magnetic Property part 481 can also be opposite with the modes of emplacement of the second magnetic part 482.
Optionally, there is at least one second cleaning position 415 between the first cleaning position 414 and cleaning solution drainage hole 413, The quantity of first cleaning position 414 is at least two, and at least two first cleaning positions 414 and at least one second cleaning position 415 are suitable Secondary setting.The quantity of first magnetic part 481 is equal to the quantity of the first cleaning position 414, and the quantity of the second magnetic part 482 is equal to second The quantity of cleaning position 415 and cleaning solution drainage hole 413 and, and respectively correspond cleaning position 414 and cleaning solution drainage hole 413.Also It is to say, reaction vessel turns between cleaning solution drainage hole 413 from cleaning solution inlet opening 412, and reaction vessel has multiple stops Position, i.e., above-mentioned the first cleaning position 414 and the second cleaning position 415 increase by the first magnetic part at the first cleaning position 414 481, increase by the second magnetic part 482 at the second cleaning position 415, the adsorption process of magnetic particle can be increased, and then improve cleaning Effect guarantees the accuracy of pattern detection.
It is understood that the quantity of cleaning position can be two, three, four or even more.When the first cleaning position When 414 quantity is two, corresponding two the first cleaning positions 414 of two the first magnetic parts 481 can be set, it can also be with one For the first cleaning position 414, another is the second cleaning position 415, and corresponding first cleaning position 414 of the first magnetic part 481, second is magnetic Part 482 corresponds to the second cleaning position 415;When the quantity of cleaning position 414 be three when, can two the first cleaning positions 414, respectively Corresponding two the first magnetic parts 481, second cleaning position 415, corresponding second magnetic part 482, etc..It is understood that Be, the quantity setting of the first magnetic part 481 and the second magnetic part 482 can corresponding cleaning position, it is unrestricted in principle.
Further, the first adjacent magnetic part 481 is towards the magnetic direction of reaction vessel on the contrary, adjacent two second The pole orientation of magnetic part 482 is opposite.That is, when there are two the first adjacent magnetic part 481, adjacent two first The magnetism of magnetic part 481 towards reaction vessel is opposite, that is, the pole N of one of them the first magnetic part 481 is towards reaction vessel, phase The pole S of adjacent another first magnetic part 481 is towards reaction vessel.When there are two the second adjacent magnetic part 482, adjacent two The pole orientation of a second magnetic part 482 is opposite.The i.e. adjacent pole N is reversed with the pole S, as the pole N upward with the pole S downward.This Sample can increase the magnetic induction intensity of reaction vessel acquisition, improve adsorption effect, and then improve cleaning effect.
Again optionally, cleaning solution inlet opening 412 and cleaning solution drainage hole 413 are multiple, each cleaning solution inlet opening 412 and Each cleaning solution drainage hole 413 is alternately placed along the circumferential of Magneto separate pedestal.First magnetic part 481 and the second magnetic part 482 Group number is equal with the quantity of cleaning solution inlet opening 412, and one group corresponding with the second magnetic part 482 of each group of the first magnetic part 481 clear Washing lotion inlet opening 412 and cleaning solution drainage hole 413.That is, with corresponding cleaning solution inlet opening 412 and cleaning solution drainage hole 413 are denoted as one group, the first magnetic part 481 needed for remembering between one group of cleaning solution inlet opening 412 and cleaning solution drainage hole 413 and the The quantity of two magnetic parts 482 is one group, and above-mentioned two group of number is identical, it can the corresponding cleaning solution inlet opening 412 of setting multiple groups With cleaning solution drainage hole 413, corresponding cleaning solution injecting mechanism 42 is identical as the quantity of cleaning solution output mechanism 43, correspondingly, The first magnetic part 481 and the second magnetic part 482 of corresponding group number are set.That is, Magneto separate cleaning assembly 4 has multistage cleaning function Can, i.e., each reaction vessel can carry out separating for several times cleaning, guarantee cleaning effect, and then improve the accuracy of pattern detection.
In the present embodiment, the quantity of cleaning solution injecting mechanism 42 and cleaning solution output mechanism 43 is respectively three, cleaning Machine is discharged with cleaning solution injecting mechanism 42 and cleaning solution respectively in the quantity and position of liquid inlet opening 412 and cleaning solution drainage hole 413 Structure 43 is adapted, i.e., reaction vessel can carry out three rank cleanings, guarantees cleaning effect, and then improve the accuracy of pattern detection.And And the cleaning position between each cleaning solution inlet opening 412 and cleaning solution drainage hole 413 can be arranged according to above-mentioned quantity, and The first magnetic part 481 and the second magnetic part 482 is respectively set, will not repeat them here.It should be noted that every group of cleaning solution into The quantity of cleaning position between fluid apertures 412 and cleaning solution drainage hole 413 may be the same or different, as between rank with two The quantity of cleaning position is equal between secondary rank, specifically, the quantity of cleaning position is three, respectively two the first cleaning positions 414 and one A second cleaning position 415;It is as different in cleaned bit quantity between a rank between rank three times, specifically, the quantity of cleaning position is four, Respectively three the first cleaning positions 414 and second cleaning position 415.
Specifically, reaction vessel is from 411 quilt of manhole appendix when Magneto separate cleaning assembly 4 carries out the cleaning of three ranks to reaction vessel It is placed on Magneto separate pedestal 41, Magneto separate pedestal 41 drives reaction vessel to move to the cleaning solution inlet opening 412 between a rank Place, adds cleaning solution into reaction vessel from cleaning solution injecting mechanism 42;Then, Magneto separate pedestal 41 drives reaction vessel movement Cleaning solution drainage hole 413 between a rank, during the motion, reaction vessel successively pass through two 414 Hes of the first cleaning position One the second cleaning position 415, is adsorbed by the first magnetic part 481 and the second magnetic part 482 respectively so that magnetic particle be loosened and It is relatively moved in cleaning solution, realizes the cleaning between a rank, and pass through cleaning solution output mechanism 43 at cleaning solution drainage hole 413 Discharge cleaning waste liquid;Magneto separate pedestal 41 drives reaction vessel to move to second-order from the cleaning solution drainage hole 413 of the first rank It at cleaning solution inlet opening 412, and then is cleaned between secondary rank, it is to be understood that cleaning between secondary rank, the three times cleaning between rank Cleaned between a rank identical, what is only acted repeats, and does not repeat one by one again.After the completion of being cleaned between rank three times, Magneto separate pedestal 41 drives reaction vessel to return to manhole appendix 411, and is taken away reaction vessel by reaction vessel grabbing assembly 5.Show Example, the first magnetic part 481 and the second magnetic part 482 are magnet.
Each technical characteristic of embodiment described above can be combined arbitrarily, for simplicity of description, not to above-mentioned reality It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited In contradiction, it is all considered to be the record scope of this specification.
Above-described embodiments merely represent several embodiments of the utility model, the description thereof is more specific and detailed, But it should not be understood as limiting the scope of the patent of the utility model.It should be pointed out that for the common of this field For technical staff, without departing from the concept of the premise utility, various modifications and improvements can be made, these all belong to In the protection scope of the utility model.Therefore, the scope of protection shall be subject to the appended claims for the utility model patent.

Claims (46)

1. a kind of Full-automatic chemiluminescence immunoassay analysis meter, which is characterized in that including the sample examination for sample loading and reagent Agent loading assembly, the separate injection needle for suction sample and reagent, the mixing seat for mixing, for be incubated for and shine detection incubate It educates and surveys optical assembly, the reaction vessel crawl group for the Magneto separate cleaning assembly of separation cleaning and for transporting reaction vessel Part;
The Magneto separate cleaning assembly and described be incubated for survey the same side that optical assembly is located at the sample reagent loading assembly, and institute It states Magneto separate cleaning assembly to be disposed adjacent with incubation survey optical assembly, the mixing seat is located at the sample reagent loading assembly It is surveyed between optical assembly with the incubation;
The separate injection needle is located at the top of the sample reagent loading assembly, and can be transferred to respectively sample and reagent described In the reaction vessel for mixing seat;The reaction vessel grabbing assembly surveys optical assembly and the magnetic in the mixing seat, the incubation The reaction vessel is transported between separation cleaning component.
2. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that the full-automatic chemical hair Light immunity analysis instrument further includes carrying platform, and the sample reagent loading assembly is located at the right side of carrying platform, the Magneto separate Cleaning assembly and described be incubated for survey the left rear side that optical assembly is located side by side at the carrying platform, reaction vessel grabbing assembly position In the front side of the carrying platform.
3. Full-automatic chemiluminescence immunoassay analysis meter according to claim 2, which is characterized in that the Magneto separate cleaning group Part is located at the sample reagent loading assembly and the incubation is surveyed between optical assembly, and the mixing seat is located at Magneto separate cleaning Between component and the reaction vessel grabbing assembly.
4. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that the sample reagent loads Component includes for the annular sample disk of sample loading and the reagent disc for loaded reagent and reagent pot, and the reagent disc can It is rotatably arranged in the reagent pot, the annular sample disk is coaxially sheathed on the outside of the reagent pot, and the ring Shape sample disk rotates independently of each other with the reagent disc.
5. Full-automatic chemiluminescence immunoassay analysis meter according to claim 4, which is characterized in that the sample reagent loads Component further includes the needle cleaning structure for cleaning separate injection needle, and the needle cleaning structure is set on the annular sample disk, and Between two adjacent sample racks.
6. Full-automatic chemiluminescence immunoassay analysis meter according to claim 5, which is characterized in that the sample reagent loads Component further includes the identification code scanner for scanning recognition code, is provided with scanning notch on the annular sample disk;
The identification code scanner can scan the identification code of sample container on the annular sample disk, the identification code scanner The identification code of reagent container in the reagent pot can also be scanned through the scanning notch.
7. Full-automatic chemiluminescence immunoassay analysis meter according to claim 6, which is characterized in that the identification code scanner It is fixedly installed on the outside of the annular sample disk, the annular sample disk drives the sample container successively to turn to the knowledge It is scanned at other code scanner;The scanning notch corresponds to the identification code scanner, and the reagent disc drives the reagent Container is successively turned at the position for scanning notch and is scanned.
8. Full-automatic chemiluminescence immunoassay analysis meter according to claim 6 or 7, which is characterized in that two adjacent institutes It states between annular sample disk and there is default spacing to form the scanning notch, there is scanning window on the reagent pot, it is described Scanning window, the scanning notch and the identification code scanner correspond to each other, and the reagent disc drives multiple reagents to hold Device rotation, moves to the reagent container successively at the scanning window, and reagent described in the identification code scanner scanning holds The identification code of device.
9. Full-automatic chemiluminescence immunoassay analysis meter according to claim 8, which is characterized in that the sample reagent loads Component further includes refrigeration part, and the refrigeration part is located at the lower section of the reagent disc, and deviates the center of the reagent pot, is used Freeze in the reagent pot.
10. Full-automatic chemiluminescence immunoassay analysis meter according to claim 9, which is characterized in that the sample reagent dress Carrying component further includes cold end fin and cold end fan, and the cold end fin and the cold end fan are set to the refrigeration part Cold end and it is arranged close to the reagent the bottom of a pan, one end of the cold end fin is bonded with the cold end of the refrigeration part, institute The other end or side that cold end fan is set to the cold end fin are stated, the cold end fan drives the gas in ambient enviroment Flow through the cold end fin.
11. Full-automatic chemiluminescence immunoassay analysis meter according to claim 10, which is characterized in that the sample reagent dress Carrying component further includes hot-side heat dissipation device and conducting-heat elements, and the hot-side heat dissipation device is connect with the hot end of the refrigeration part, and position In the outside of the reagent pot;The conducting-heat elements connect with the hot-side heat dissipation device and correspond to the outer of the scanning window Side.
12. Full-automatic chemiluminescence immunoassay analysis meter according to claim 4, which is characterized in that the sample reagent dress Carrying component further includes the reagent pot cover for being covered on the reagent pot;The reagent pot cover has multiple suction reagent wells, multiple described The radial direction for inhaling reagent wells along the reagent disc pot is arranged, and is located in a straight line, and the separate injection needle can extend into any Reagent is drawn in the suction reagent wells.
13. Full-automatic chemiluminescence immunoassay analysis meter according to claim 12, which is characterized in that the sample reagent dress Carrying component further includes switch cover, has the opening that takes for being placed or taken out reagent container on the reagent pot cover, described to open It closes lid and switchably takes opening positioned at the described of the reagent pot cover.
14. Full-automatic chemiluminescence immunoassay analysis meter according to claim 13, which is characterized in that the reagent pot cover is also Including the cold plate and drip tray being oppositely arranged, the cold plate is detachably connected with the drip tray, and the cold plate with Airflow channel is formed between the drip tray, the cold air in the reagent pot is able to enter the airflow channel;
The reagent wells of inhaling include that first on the cold plate inhales reagent wells and the second suction on the drip tray Reagent wells;The first suction reagent wells are oppositely arranged with the second suction reagent wells, and the profile energy of the first suction reagent wells The described second profile for inhaling reagent wells is enough completely covered, the first suction reagent wells are connected with external environment, and described second inhales It is connected in reagent wells and the reagent pot.
15. Full-automatic chemiluminescence immunoassay analysis meter according to claim 14, which is characterized in that described first inhales reagent The hole wall in hole extends to form first annular barrel towards the drip tray, and the inner wall of the first annular barrel passes through described the One suction reagent wells are contacted with external environment, and the outside wall surface of the first annular barrel is contacted with the airflow channel local environment;
The first annular barrel can be completely covered described second far from one end profile of the first suction reagent wells and inhale reagent The profile in hole.
16. Full-automatic chemiluminescence immunoassay analysis meter according to claim 14 or 15, which is characterized in that described second inhales The hole wall of reagent wells extends to form the second annular tube wall towards the cold plate;
Second annular tube wall inhales reagent wells towards the direction of the cold plate in shrink mouth shape by described second;
There is drainage hole, the bottom of the reagent pot has the drainage channel for draining condensed water, described on the drip tray Drainage hole is connected to the drainage channel.
17. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that have on the mixing seat There are a sample mixing portion and substrate mixing portion, sample mixing portion is used to carry at least one and reacts appearance with sample and reagent Device, and for mixing sample and reagent in the reaction vessel, the carrying of substrate mixing portion has the reaction vessel of substrate, and For mixing determinand and substrate in the reaction vessel, the mixing seat is able to drive sample mixing portion and the bottom Object mixing portion carries out mixing operation simultaneously.
18. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that the full-automatic chemical Luminescence immunoassay instrument further includes dispensing punch block, and the dispensing punch block is located at the rear side above the sample reagent loading assembly, It is provided with dispensing driving portion on the dispensing punch block, to drive the dispensing needle movement.
19. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that the full-automatic chemical Luminescence immunoassay instrument further includes separate injection needle swab, and the separate injection needle swab is sheathed on the separate injection needle, and can be with institute It states separate injection needle to move horizontally, the separate injection needle swab can be to the outer wall washing of the separate injection needle.
20. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that the full-automatic chemical Luminescence immunoassay instrument further includes service sink and the mixing platform for carrying the mixing seat, and the service sink is set to described It mixes on platform, the service sink is for picking up the cleaning waste liquid after the separate injection needle inner wall washing.
21. Full-automatic chemiluminescence immunoassay analysis meter according to claim 20, which is characterized in that the sample reagent dress It carries component and has and inhale sample station and multiple suction reagent wells, the mixing seat tool has a sample mixing portion, the suction sample station, more A suction reagent wells, sample mixing portion are conllinear with the service sink.
22. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that light group is surveyed in the incubation Part includes being incubated for block and surveying light part, and the light part of surveying is installed on the trailing flank for being incubated for block, and having on the incubation block is in battle array Multiple incubation holes of setting are arranged, the incubation hole is described after incubation for placing the reaction vessel and carrying out incubation operation Reaction vessel carries out the detection that shines by the survey light part.
23. Full-automatic chemiluminescence immunoassay analysis meter according to claim 22, which is characterized in that on the incubation block also With light-measuring hole, the light-measuring hole corresponds to the survey light part setting, and is located remotely from the side for being incubated for hole, the institute after incubation It states reaction vessel to be transferred in the light-measuring hole from the incubation hole, and the detection that shines is carried out by the survey light part.
24. Full-automatic chemiluminescence immunoassay analysis meter according to claim 22, which is characterized in that light group is surveyed in the incubation Part further includes substrate economizer bank and substrate heat-conducting block, and the substrate economizer bank and the substrate heat-conducting block are all set in the incubation In block, the substrate heat-conducting block is used to heat the substrate in the substrate economizer bank.
25. Full-automatic chemiluminescence immunoassay analysis meter according to claim 22, which is characterized in that light group is surveyed in the incubation Part further includes cleaning solution preheating container, has the entrance and exit passed in and out for cleaning solution, and the cleaning solution preheating container is set to In the incubation block, for heating cleaning solution.
26. Full-automatic chemiluminescence immunoassay analysis meter according to claim 22, which is characterized in that the full-automatic chemical Luminescence immunoassay further includes removal waste fluid component, and the removal waste fluid component is liftably set to the left side for being incubated for block.
27. Full-automatic chemiluminescence immunoassay analysis meter according to claim 26, which is characterized in that light group is surveyed in the incubation Part is including being incubated for block and surveying light part, the row being incubated on block with light-measuring hole and for accommodating the reaction vessel after detecting Waste liquid hole, the light-measuring hole and waste discharge fluid apertures side by side and are disposed adjacent, and the reaction vessel is discharged in the removal waste fluid component decline In waste liquid when to the reaction vessel shading in the light-measuring hole.
28. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that the Magneto separate cleaning Component is disc-shaped structure, including Magneto separate pedestal, injection needle, drain needle and magnet;
With manhole appendix and the cleaning solution inlet opening and cleaning solution drainage hole that are sequentially arranged, the disengaging on the Magneto separate pedestal Hole is for being put into or taking out the reaction vessel to be separated;It is described that the Magneto separate pedestal drives the reaction vessel rotation to make Reaction vessel sequentially corresponds to the cleaning solution inlet opening, cleaning solution drainage hole and the manhole appendix;The injection needle is set to institute It states in cleaning solution inlet opening, for adding cleaning solution to the reaction vessel;The drain needle liftable correspondence cleaning The setting of liquid drainage hole, the cleaning waste liquid for being discharged in the reaction vessel;
The magnet is set in the Magneto separate pedestal, and is located at the two sides of the reaction vessel rotation path.
29. Full-automatic chemiluminescence immunoassay analysis meter according to claim 28, which is characterized in that the Magneto separate cleaning Component further includes Magneto separate swab and drain lifting unit, and the drain lifting unit is liftably installed on the Magneto separate pedestal On;The drain needle is set on the drain lifting unit, and the Magneto separate swab is sheathed on the outside of the drain needle, and position In the cleaning solution drainage hole, the drain lifting unit drive the drain needle relative to the Magneto separate swab decline or on When rising, the Magneto separate swab can be to the outer wall washing of the drain needle.
30. Full-automatic chemiluminescence immunoassay analysis meter according to claim 28, which is characterized in that the magnet includes the One magnet and the second magnet, first magnet and second magnet are distributed along the side of the Magneto separate pedestal, and described First magnet and second magnet are located at the two sides of the reaction vessel rotation path;
The Magneto separate pedestal has the first cleaning position between the cleaning solution inlet opening and the cleaning solution drainage hole, described First magnet corresponds to the first cleaning position setting, and institute's second magnet corresponds to the cleaning solution drainage hole setting;
On vertical line direction, the magnetic pole line of first magnet and the angle of vertical line are the first angle, second magnetic The magnetic pole line of iron and the angle in the vertical line direction are the second angle, wherein first angle and second angle It is different.
31. Full-automatic chemiluminescence immunoassay analysis meter according to claim 30, which is characterized in that the Magneto separate pedestal With rotary shaft, the Magneto separate pedestal drives the reaction vessel to rotate around the rotary shaft;The extension side of the rotary shaft To, magnetic pole line and the straight line phase extending direction of the rotary shaft where of first magnet parallel with the vertical line It hands over.
32. Full-automatic chemiluminescence immunoassay analysis meter according to claim 31, which is characterized in that first magnet Magnetic pole line is vertical with the vertical line, and the magnetic pole line of second magnet is parallel with the vertical line.
33. according to the described in any item Full-automatic chemiluminescence immunoassay analysis meters of claim 30 to 32, which is characterized in that described Also there is at least one second cleaning position, the quantity of first cleaning position between first cleaning position and the cleaning solution drainage hole It is at least two;
The quantity of first magnet is equal to the quantity of first cleaning position, and the quantity of second magnet is equal to described second The quantity of cleaning position and the cleaning solution drainage hole and, and respectively correspond second cleaning position and the cleaning solution drainage hole;
Adjacent first magnet towards described reaction vessel one end magnetism on the contrary, adjacent two second magnet Pole orientation is opposite.
34. according to the described in any item Full-automatic chemiluminescence immunoassay analysis meters of claim 30 to 32, which is characterized in that described Cleaning solution inlet opening is multiple, each cleaning solution inlet opening and each cleaning solution drain with the cleaning solution drainage hole It is alternately placed along the circumferential of the Magneto separate pedestal in hole;
First magnet and the group number of second magnet are equal with the quantity of the cleaning solution inlet opening, described in each group Cleaning solution inlet opening described in one magnet is one group corresponding with second magnet and the cleaning solution drainage hole.
35. Full-automatic chemiluminescence immunoassay analysis meter according to claim 28, which is characterized in that the Magneto separate cleaning Component further includes magnetic shielding part, and the magnetic shielding part is sheathed on the outside of the Magneto separate pedestal, for shielding the magnetic The magnetic field that iron generates.
36. Full-automatic chemiluminescence immunoassay analysis meter according to claim 28, which is characterized in that the Magneto separate pedestal On also have substrate injection hole, the substrate injection hole is between the manhole appendix and the cleaning solution drainage hole, through described Substrate injection hole adds substrate into the reaction vessel.
37. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that the full-automatic chemical Luminescence immunoassay instrument further includes two reaction vessel loading assemblies and carrying platform, and two reaction vessel loading assemblies are simultaneously Row is set to the front left side of the carrying platform, and is located at the lower section of the reaction vessel grabbing assembly, and the reaction vessel is grabbed Take component that the reaction vessel in the reaction vessel loading assembly is transferred to the mixing seat.
38. the Full-automatic chemiluminescence immunoassay analysis meter according to claim 37, which is characterized in that the full-automatic chemical Luminescence immunoassay instrument further includes the ash can that opening is arranged at top, and the ash can is set to the reaction vessel loading assembly Right side, and it is located at the lower section of the reaction vessel grabbing assembly, the described anti-of waste liquid will be discharged in the reaction vessel grabbing assembly Container is answered to be put into the ash can by the opening.
39. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that the Magneto separate cleaning Component has substrate injection hole, and optical assembly is surveyed in the incubation has substrate economizer bank, the automatic chemiluminescence immunoassay Instrument further includes two substrate loading parts, and the substrate loading station is in the front side of the sample reagent loading assembly, for carrying Substrate container, and pass through pipeline by the substrate in substrate container after substrate economizer bank preheating, by the substrate injection hole It is transported in the reaction vessel.
40. Full-automatic chemiluminescence immunoassay analysis meter according to claim 39, which is characterized in that the full-automatic chemical Luminescence immunoassay instrument further includes substrate constant displacement pump, before the substrate constant displacement pump is set to the sample reagent loading assembly Side, and the substrate container, the substrate economizer bank and the substrate injection hole are respectively communicated with by pipeline, it is the conveying of substrate Power is provided.
41. Full-automatic chemiluminescence immunoassay analysis meter according to claim 19, which is characterized in that the full-automatic chemical Luminescence immunoassay instrument further includes the first divide syringe and carrying platform, and it is flat that first divide syringe is located at the carrying The rear side of platform, first divide syringe pass through pipeline respectively and are connected to the separate injection needle and the separate injection needle swab, will be clear Washing lotion is supplied to the separate injection needle and the separate injection needle swab.
42. Full-automatic chemiluminescence immunoassay analysis meter according to claim 41, which is characterized in that the full-automatic chemical Luminescence immunoassay instrument further includes the second divide syringe, and second divide syringe is connected to first divide syringe Between the separate injection needle, and it is located at the rear side positioned at the carrying platform, makes the separate injection needle suction sample or reagent.
43. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that the Magneto separate cleaning Component includes Magneto separate swab and injection needle, and the Full-automatic chemiluminescence immunoassay analysis meter further includes Magneto separate syringe and hold Carrying platform, the Magneto separate syringe are located at the left side of the carrying platform, the Magneto separate syringe by pipeline with it is described Injection needle connection, cleaning solution is delivered into the reaction vessel, the Magneto separate syringe also passes through pipeline and the magnetic Swab connection is separated, cleaning solution is supplied to the Magneto separate swab.
44. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that the full-automatic chemical Luminescence immunoassay instrument further includes vacuum chamber, the first vacuum pump and carrying platform, the vacuum chamber and first vacuum pump position In the rear side of carrying platform, the outlet of the vacuum chamber is connect with first vacuum pump, and the vacuum chamber inlet passes through pipeline It is connect with Magneto separate cleaning assembly, is clear in the reaction vessel after Magneto separate cleaning assembly cleaning by the vacuum chamber The discharge for washing waste liquid provides power, and the entrance of the vacuum chamber also passes through pipeline and connect with incubation survey optical assembly, by described Vacuum chamber surveys the optical assembly discharge of waste liquid after detection that shine and provides power for described be incubated for.
45. Full-automatic chemiluminescence immunoassay analysis meter according to claim 44, which is characterized in that the Magneto separate cleaning Component further includes Magneto separate swab and drain needle, and the Magneto separate swab is sheathed on outside the drain needle, first vacuum Pump is also connect by pipeline with the Magneto separate swab, and the discharge for cleaning waste liquid in the Magneto separate swab provides power.
46. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, which is characterized in that the full-automatic chemical Luminescence immunoassay instrument further includes the second vacuum pump, separate injection needle swab, service sink and carrying platform, and second vacuum pump is located at The rear side of the carrying platform, second vacuum pump are connect with the separate injection needle swab and the service sink respectively, are described The discharge that waste liquid is cleaned in separate injection needle swab and the service sink provides power.
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WO2019154334A1 (en) * 2018-02-08 2019-08-15 成都深迈瑞医疗电子技术研究院有限公司 Fully automated chemiluminescence immunoassay analyser
US12287328B2 (en) 2018-02-08 2025-04-29 Chengdu Shen Mindray Medical Electronics Technology Research Institute Co., Ltd. Fully automated chemiluminescence immunoassay analyzer
CN109520930A (en) * 2018-12-29 2019-03-26 苏州汶颢微流控技术股份有限公司 A kind of elisa assay instrument
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