CN1204908C - Deafness and tinnitus treating Chinese medicine and its prepn - Google Patents

Abstract

The present invention relates to a Chinese medicine for treating inductive, neuropathic, otosclerosis and sudden deafness and tinnitus. The Chinese medicine is prepared from ginseng, angelica, jujube seed, cornus officinalis, antler, gastrodia tuber, chuanxiong rhizome, grassleaved sweetflag rhizome, nutgrass galingale rhizome, bupleurum, red peony root, safflower, leech, gadflies, oysters, liquorice, pangolin, etc. By uisng the medicine, via the clinical application and the comparison application test, by uisng the medicine, the cure rate reaches 60%, and the total effective rate reaches 91%.

Description

A kind of Chinese medicine for the treatment of deafness and tinnitus and preparation method thereof

Technical field

The invention belongs to the field of Chinese medicines, specifically a kind of Chinese medicine and preparation method thereof.The present invention be more particularly directed to a kind of medicament for the treatment of Irritability, nerve, otosclerosis, sudden deafness, tinnitus and preparation method thereof.

Background technology

Deafness, tinnitus, dizzy be multiple disease of inner ear symptom, be multiple harmful factor damage cochlea and acous result, as viral infection, ototoxic drug, noise, nephropathy, hypertension and autoimmune disease etc., still do not have specific medicament at present.

Summary of the invention

The invention provides a kind of pure Chinese drugs agentia for the treatment of Irritability, nerve, otosclerosis, sudden deafness, tinnitus and preparation method thereof.

The present invention is the Chinese drugs agentia of being made by the following weight proportion raw material: Radix Ginseng 500g, Radix Angelicae Sinensis 750g, Semen Ziziphi Spinosae 750g, Fructus Corni 500g, Cornu Cervi Pantotrichum 500g, Rhizoma Gastrodiae 250g, Rhizoma Chuanxiong 500g, Rhizoma Acori Graminei 500g, Rhizoma Cyperi 500g, Radix Bupleuri 500g, Radix Paeoniae Rubra 500g, Flos Carthami 500g, Hirudo 500g, Tabanus 500g, Concha Ostreae 500g, Radix Glycyrrhizae 500g, Squama Manis 250g.

The manufacture method of preparation of the present invention is as follows:

(1) takes by weighing Semen Ziziphi Spinosae 750g parching to brown; Fructus Corni 500g wine is fried; Rhizoma Cyperi 500g vinegar is fried, and promptly is sprayed at the 50g mature vinegar and soaks stir-fry again after the receipts on the 500g Rhizoma Cyperi; Hirudo 500g, Radix Glycyrrhizae 15g, by Hirudo: the proportional arrangement of Radix Glycyrrhizae=100: 3, pull Hirudo out after in covering the water of their 2cm, soaking half an hour and dry, fry again; Tabanus 500g fries; Radix Glycyrrhizae 500g adds honey and soaks to pull out after half an hour and dry the back and do and fry; Fry again behind the Rhizoma Chuanxiong 500g processed with wine, promptly 50 ℃ of Chinese liquor, 50 grams are sprayed at and fry again after soaking receipts on the 500g Rhizoma Chuanxiong; Above-mentioned Chinese medicine is ground into face till all frying routinely and extremely doing again, and is standby;

(2) take by weighing Radix Ginseng 500g, Radix Angelicae Sinensis 750g, Rhizoma Acori Graminei 500g, Radix Bupleuri 500g, Radix Paeoniae Rubra 500g, Flos Carthami 500g, Concha Ostreae 500g, Squama Manis 250g, Cornu Cervi Pantotrichum 500g, Rhizoma Gastrodiae 250g again, dry respectively routinely, be ground into face, standby;

(3) various mix homogeneously, pills routinely in step (1) and (2).

The usage and dosage of medicament of the present invention: twice of every day oral " audition improvement ball ", each 10 grams, per 30 days is a course of treatment.The minor takes the circumstances into consideration to subtract and takes.

The function of medicament of the present invention: the blood stasis dispelling that stagnates of QI and blood regulating, row, tonifying speen and tonifying kidney is comfortablely had one's ideas straightened out, depressed liver-energy dispersing and function of gallbladder promoting.

Cause of disease mechanism of the present invention and pharmacology analysis:

The traditional Chinese medical science is thought: a little less than the heart was insufficiency of the spleen, deficiency of the kidney was disturbed on the phlegm-fire, swelling knot ear key, and depression of liver-QI and superinverse is blocked clear key, or depressed emotion, liver-fire catharsis bar reaches and presses down the ear fire-transformation.Disturb key clearly on the fire of liver and gall, all can cause deafness, tinnitus.Injured gathering of taste wet into expectorant, disturbs on the phlegm-fire, and obstructing airway also can cause deafness, tinnitus.The abundant bone marrow of kidney qi, and it is clever real to get audition.As its tongue body deficiency, the brain inanition, can not on give in ear, or spleen YANG deficiency, clear QI failing to ascend also can cause deafness, tinnitus.

Radix Ginseng in the present invention's the medicament, sweet in the mouth, warm in nature is returned lung meridian, strongly invigorating primordial QI, admittedly and take off spermatogenesis and be apt to control consumptive disease, void, damage; Radix Angelicae Sinensis, benefiting blood and regulating blood circulation is transferred with pain relieving; Semen Ziziphi Spinosae is gone into the heart, spleen, liver and gall warp, tranquilizing by nourishing the heart, nourishing the liver and kidney; Fructus Corni is returned liver, kidney channel, and beneficial tonifying liver warp nourishes essence and blood, the kidney invigorating gas, increases marrow, treatment deficiency of YIN tinnitus; The same Fructus Corni of Cornu Cervi Pantotrichum function; Rhizoma Gastrodiae is returned gallbladder meridian, endogenous wind stopping is relieving convulsion, and the kind M of controlling is mended five kinds of strain and seven kinds of impairment, and logical blood is dirty, has one's ideas straightened out, and with Fructus Corni, Cornu Cervi Pantotrichum compatibility, the tonifying liver liver nourishing cooperates Radix Ginseng, unit on the moisturizing, and unit under two moisturizings, its water is energetic, is encapsulated in the ear key, contented its acute hearing on continually.Go into the liver and gall warp, soothing the liverly give birth to sun, control under the yang-energy and let out, the fire of flat gallbladder liver, three warmers.The merit of more than seeing flavor, can mend, can support, can help others clearly, altogether ginseng QI invigorating kidney tonifying.

Rhizoma Chuanxiong in the medicament of the present invention, circulation of qi promoting are had one's ideas straightened out, dispeiling pathogenic wind and removing dampness.Rhizoma Cyperi goes into liver, spleen, tri-jiao channel, and its resolving depression of regulating the flow of vital energy makes irritability happy.Rhizoma Acori Graminei, GUIXIN, liver, spleen channel can be had one's ideas straightened out, regulate the flow of vital energy, be invigorated blood circulation; Squama Manis, active the stimulating the menstrual flow of subsiding a swelling; Concha Ostreae, controlling nocturnal emission with astringent drugs, eliminating stagnation, softening the hard mass; Hirudo, Tabanus, removing blood stasis with potent drugs blood, eliminating stagnation; Flos Carthami, Radix Paeoniae Rubra, blood circulation promoting and blood stasis dispelling.

All medicine mutually 5, the QI invigorating kidney tonifying, expelling pathogenic wind and restoring the functions of orifices in face, the resolving depression heat clearing away, tranquilizing by nourishing the heart, thus reach QI and blood and in, the purpose that equilibrium between yin and yang and deafness, tinnitus are all dispelled.

The present invention compares than prior art has following advantage: 1, cost is low, convenient, fast, can reach the purpose for the treatment of both the principal and secondary aspects of a disease.2 is effective.Adopt medicament of the present invention, through clinical practice and contrast application testing, cure rate reaches 60%, and total effective rate reaches 91%.

The working of an invention mode:

Toxicity test report of the present invention

Be subjected to the reagent thing: product of the present invention

Test unit: Nanjing Pharmacy Univ

This test is undertaken by the design of toxicological test code requirement

1, acute toxicity test: mouse stomach gives product capsule of the present invention, successive administration 10 days, and every day, maximum consumption was equivalent to crude drug 50g/kg, was 100 times of clinical dosage, result of the test, none death of mice.

2, long term toxicity test: rat is 50 times of clinical dosage by being equivalent to crude drug 25g/kg every day, successive administration 30 days, animal appetite, body weight, all are movable normal for defecation etc., routine blood test and hepatic and renal function are normal, and major organs pathological sections such as heart, stomach, spleen, adrenal gland, ovary, testis, lung all do not have the observability pathological change, and this result shows that it is safe that the present invention uses with dosage by clinical plan.

Claims (1)

1, a kind of Chinese medicine for the treatment of Irritability, nerve, otosclerosis, sudden deafness, tinnitus is characterized in that this Chinese medicine makes as follows:

(1) takes by weighing Semen Ziziphi Spinosae 750g parching to brown; Fructus Corni 500g wine is fried; Rhizoma Cyperi 500g vinegar is fried, and promptly is sprayed at the 50g mature vinegar and soaks stir-fry again after the receipts on the 500g Rhizoma Cyperi; Hirudo 500g, Radix Glycyrrhizae 15g, by Hirudo: the proportional arrangement of Radix Glycyrrhizae=100: 3, pull Hirudo out after in covering the water of their 2cm, soaking half an hour and dry, fry again; Tabanus 500g fries; Radix Glycyrrhizae 500g adds honey and soaks to pull out after half an hour and dry the back and do and fry; Fry again behind the Rhizoma Chuanxiong 500g processed with wine, promptly 50 ℃ of Chinese liquor, 50 grams are sprayed at and fry again after soaking receipts on the 500g Rhizoma Chuanxiong; Above-mentioned Chinese medicine is ground into face till all frying routinely and extremely doing again, and is standby;

(2) take by weighing Radix Ginseng 500g, Radix Angelicae Sinensis 750g, Rhizoma Acori Graminei 500g, Radix Bupleuri 500g, Radix Paeoniae Rubra 500g, Flos Carthami 500g, Concha Ostreae 500g, Squama Manis 250g, Cornu Cervi Pantotrichum 500g, Rhizoma Gastrodiae 250g again, dry respectively routinely, be ground into face, standby;

(3) various mix homogeneously, pills routinely in step (1) and (2).