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CN102240357B - Medicament for treating tinnitus and preparation method thereof - Google Patents

Medicament for treating tinnitus and preparation method thereof Download PDF

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Publication number
CN102240357B
CN102240357B CN 201110232755 CN201110232755A CN102240357B CN 102240357 B CN102240357 B CN 102240357B CN 201110232755 CN201110232755 CN 201110232755 CN 201110232755 A CN201110232755 A CN 201110232755A CN 102240357 B CN102240357 B CN 102240357B
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radix
crude drug
tinnitus
treatment
medicine
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CN 201110232755
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CN102240357A (en
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俞洋
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JIANGSU SUNAN PHARMACEUTICAL INDUSTRY Co Ltd
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JIANGSU SUNAN PHARMACEUTICAL INDUSTRY Co Ltd
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Abstract

The invention discloses a medicament for treating tinnitus and a preparation method thereof. The medicament is mainly prepared from the following medicinal raw materials: 6-8g of root-bark of tree peony, 5-10g of red peony root, 8-10g of angelica sinensis, 8-10g of safflower, 10-15g of chrysanthemum, 10-15g of kudzu root, 6-10g of bupleurum, 2-5g of licorice and 10-15g of nutgrass galingale rhizome. The preparation method comprises the steps of: decocting the medicinal raw materials twice, and combining the liquid medicines filtered after decocting twice. The medicament for treating tinnitus disclosed by the invention has the advantages of high cure rate, wide range of application, short course of treatment, high effect taking speed, low price, no toxic side effect and simple formula, and is especially suitable for pregnant women, convenient to prepare and take and suitable for popularization and use.

Description

A kind of medicine for the treatment of tinnitus and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, specifically a kind of medicine for the treatment of tinnitus and preparation method thereof.
Background technology
Tinnitus is a kind ofly not have under extraneous sound, the electricity irritation condition sound that people's ear subjective feeling arrives.It should be noted that tinnitus is a kind of illusion that betides auditory system, is a kind of symptom rather than disease.Some people often feel to have in the ear some special sound as drone, neigh or sharp-pointed whistle etc., but can not find corresponding sound source on every side, this situation is tinnitus.Tinnitus makes that the people upsets, uneasy in either sitting or lying, and severe patient can affect normal live and work.Medical science thinks that tinnitus is the common sympton of various disease conditions, and normal and deaf the merging occurs, and is mainly in middle-aged and elderly people, so " deaf for ring gradually, ringing is the deaf beginning " say.Discussion to tinnitus in the ancient medical book is a lot, as saying in China's doctor's work Huangdi's Internal Classics the earliest: and " deficiency of marrow-reservoir, then vertigo and tinnitus ", " QI of the upper portion of the body being insufficient ... ear is bitter ring for it ".Say in the Ming Dynasty doctor nationality Jing-Yue Complete Works: " kidney qi is sufficient, normal hearing and eyesight then, if many impairments caused by overstrain vim and vigour, the loss of essence kidney is exhausted, must cause deaf.The old friend after the middle age, every many tinnitus, such as wind and rain, as the cicada cried, the person that has a tidal wave of, be all the moon decline deficiency of the kidney and right ".Over thousands of years, traditional Chinese medical science scholar is under global theory and the guidance of determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs principle, and the therapy for treating tinnitus such as the side's of utilization medicine, acupuncture, massage, guiding have been gained most valuable experience.If let drift, do not go treatment, final final result is deaf, and is incurable; Present common Therapeutic Method is to adopt vasodilation commonly used to control, but the crowd that this method is suitable for is narrow, and side effect is large, especially is not suitable for the anemia of pregnant woman and uses.
Summary of the invention
Goal of the invention: the first purpose of the present invention is in order to overcome the deficiencies in the prior art, provides that a kind of short treating period, instant effect, cure rate are high, cheap, the medicine of the treatment tinnitus that has no side effect.
The second purpose of the present invention is for a kind of preparation method for the treatment of the medicine of tinnitus is provided.
Technical scheme: in order to solve above-mentioned the first purpose, the technical solution adopted in the present invention is: a kind of medicine for the treatment of tinnitus, it is mainly made by following bulk drugs: Cortex Moutan 6~8g, Radix Paeoniae Rubra 5~10g, Radix Angelicae Sinensis 8~10g, Flos Carthami 8~10g, Flos Chrysanthemi 10~15g, Radix Puerariae 10~15g, Radix Bupleuri 6~10g, Radix Glycyrrhizae 2~5g, Rhizoma Cyperi 10~15g.
Preferably, the consumption of described each crude drug is: Cortex Moutan 6g, Radix Paeoniae Rubra 10g, Radix Angelicae Sinensis 8g, Flos Carthami 10g, Flos Chrysanthemi 15g, Radix Puerariae 10g, Radix Bupleuri 10g, Radix Glycyrrhizae 3g, Rhizoma Cyperi 10g.
In order to solve above-mentioned the second purpose, the technical solution adopted in the present invention is: a kind of preparation method for the treatment of the medicine of tinnitus, the method comprises the steps:
(1) consumption according to each crude drug takes by weighing each crude drug;
(2) head is fried in shallow oil operation: all crude drug in the step (1) are soaked, and the described water yield is 2 times of all crude drug gross weights, soaks 10 minutes, and after big fire was boiled, slow fire continued to decoct 20 minutes, leaches medicinal liquid, obtains filtering residue;
(3) two fry in shallow oil operation: the filtering residue that obtains in the step (2) is soaked, and this moment, the water yield was 1 times of all crude drug gross weights, and decocting time 20 minutes leaches medicinal liquid,
(4) merge: fry in shallow oil the medicinal liquid that obtains in the operation with two and fry in shallow oil the medicine that namely gets described treatment tinnitus after the medicinal liquid that obtains in the operation mixes with head.
Beneficial effect: compared with prior art, advantage of the present invention is: cure rate is high, and is applied widely, is specially adapted to the anemia of pregnant woman; Short treating period, instant effect; Cheap, have no side effect, preparation, taking convenience are suitable for promoting the use of; Prescription is simple, and is easy to use.
The specific embodiment
The present invention is further described below by specific embodiment; should be pointed out that for the person of ordinary skill of the art, under the prerequisite that does not break away from the principle of the invention; can also make some modification and improvement, these also should be considered as belonging to protection scope of the present invention.
Embodiment 1: a kind of medicine for the treatment of tinnitus of the present invention comprises that the consumption of following crude drug and each crude drug is respectively: Cortex Moutan 6g, Radix Paeoniae Rubra 10g, Radix Angelicae Sinensis 8g, Flos Carthami 10g, Flos Chrysanthemi 15g, Radix Puerariae 10g, Radix Bupleuri 10g, Radix Glycyrrhizae 3g, Rhizoma Cyperi 10g.
The preparation method of this medicine is as follows:
(1) consumption according to each crude drug takes by weighing each crude drug;
(2) head is fried in shallow oil operation: above-mentioned all crude drug are soaked, and amount of water is 2 times of all crude drug gross weights, soaks 10 minutes, and after big fire was boiled, slow fire continued to decoct 20 minutes, leaches medicinal liquid, obtains filtering residue;
(3) two fry in shallow oil operation: above-mentioned filtering residue is soaked, and this moment, the water yield was 1 times of all crude drug gross weights, and decocting time 20 minutes leaches medicinal liquid,
(4) merge: fry in shallow oil the medicinal liquid that obtains in the operation with two and fry in shallow oil the medicine that namely gets described treatment tinnitus after the medicinal liquid that obtains in the operation mixes with head.
Instructions of taking: mixed medicinal liquid divided take for 2 times on the one.
Embodiment 2: substantially the same manner as Example 1, difference is that the consumption of described each crude drug is: Cortex Moutan 8g, Radix Paeoniae Rubra 8g, Radix Angelicae Sinensis 10g, Flos Carthami 8g, Flos Chrysanthemi 10g, Radix Puerariae 15g, Radix Bupleuri 6g, Radix Glycyrrhizae 5g, Rhizoma Cyperi 15g.
Embodiment 3: substantially the same manner as Example 1, difference is that the consumption of described each crude drug is: Cortex Moutan 7g, Radix Paeoniae Rubra 8g, Radix Angelicae Sinensis 9g, Flos Carthami 9g, Flos Chrysanthemi 12g, Radix Puerariae 12g, Radix Bupleuri 8g, Radix Glycyrrhizae 2g, Rhizoma Cyperi 12g.
Embodiment 4: substantially the same manner as Example 1, difference is that the consumption of described each crude drug is: Cortex Moutan 6g, Radix Paeoniae Rubra 6g, Radix Angelicae Sinensis 8g, Flos Carthami 10g, Flos Chrysanthemi 10g, Radix Puerariae 13g, Radix Bupleuri 9g, Radix Glycyrrhizae 4g, Rhizoma Cyperi 10g.
Below further set forth the beneficial effect of medicine of the present invention by clinical case.
Clinical observation 100 routine nervous tinnitus cases with test group treatment vertebral artery type tinnitus 50 examples, compare with matched group 50 examples.Test group: the medicine described in the embodiment 1 among the present invention, be decocted in water for oral dose, every day potion, sooner or later sub-service.Taking medicine continuously 7 days is 1 course for the treatment of, and further consultation in per 7 days once.Be 4 courses for the treatment of observing time.Matched group: adopt conventional vasodilation low molecular dextran to treat quiet: each 250~500ml, every day or the next day once, 7~14 times was 1 course for the treatment of.Be 4 courses for the treatment of observing time.
Criterion of therapeutical effect is drafted with reference to State Administration of Traditional Chinese Medicine's " traditional Chinese medical science disease Standardization of diagnosis and curative effect ":
1, cure: original transference cure, every sign turns negative, and can recover normal life and work, follows up a case by regular visits to 3 months without the recidivist;
2, produce effects: original symptom, sign obviously alleviate, through following up a case by regular visits to symptom without adding severe one;
3, effective: original symptom, sign alleviate, and seizure frequency reduces, and the outbreak persistent period is shorter, can participate in labor in general and worker;
4, invalid: symptom, sign are without improving or adding severe one.
Test group and matched group curative effect relatively see Table 1.
Table 1 test group and matched group curative effect are relatively
Figure BDA0000083235500000031
Test group treatment vertebral artery type tinnitus 100 examples, total effective rate reaches 96%, with matched group 50 routine total effective rates 54%, compares, and greatly is better than matched group.Illustrate that Drug therapy tinnitus of the present invention is evident in efficacy, have good promotional value.

Claims (3)

1. medicine for the treatment of tinnitus, it is characterized in that it is made by following bulk drugs: Cortex Moutan 6~8g, Radix Paeoniae Rubra 5~10g, Radix Angelicae Sinensis 8~10g, Flos Carthami 8~10g, Flos Chrysanthemi 10~15g, Radix Puerariae 10~15g, Radix Bupleuri 6~10g, Radix Glycyrrhizae 2~5g, Rhizoma Cyperi 10~15g.
2. a kind of medicine for the treatment of tinnitus according to claim 1 is characterized in that the consumption of described each crude drug is: Cortex Moutan 6g, Radix Paeoniae Rubra 10g, Radix Angelicae Sinensis 8g, Flos Carthami 10g, Flos Chrysanthemi 15g, Radix Puerariae 10g, Radix Bupleuri 10g, Radix Glycyrrhizae 3g, Rhizoma Cyperi 10g.
3. a kind of preparation method for the treatment of the medicine of tinnitus according to claim 1 and 2 is characterized in that the method is as follows:
(1) consumption according to each crude drug takes by weighing each crude drug;
(2) head is fried in shallow oil operation: all crude drug in the step (1) are soaked, and the described water yield is 2 times of all crude drug gross weights, soaks 10 minutes, and after big fire was boiled, slow fire continued to decoct 20 minutes, leaches medicinal liquid, obtains filtering residue;
(3) two fry in shallow oil operation: the filtering residue that obtains in the step (2) is soaked, and this moment, the water yield was 1 times of all crude drug gross weights, and decocting time 20 minutes leaches medicinal liquid,
(4) merge: fry in shallow oil the medicinal liquid that obtains in the operation with two and fry in shallow oil the medicine that namely gets described treatment tinnitus after the medicinal liquid that obtains in the operation mixes with head.
CN 201110232755 2011-08-15 2011-08-15 Medicament for treating tinnitus and preparation method thereof Expired - Fee Related CN102240357B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105596692A (en) * 2015-12-24 2016-05-25 马天宝 Composition for relieving presbycusis and tinnitus and preparation method of composition
CN107823636A (en) * 2017-12-14 2018-03-23 阜阳市平衡医疗保健器械有限公司 A kind of medicine for treating tinnitus

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1344554A (en) * 2001-09-04 2002-04-17 刘现峰 Deafness and tinnitus treating Chinese medicine and its prepn

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1344554A (en) * 2001-09-04 2002-04-17 刘现峰 Deafness and tinnitus treating Chinese medicine and its prepn

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
王坤山,王慧艳.耳鸣辨洽十二法.《光明中医杂志》.1995,(第6期),14-17. *
马俊杰 ,朱萱萱.中医药治疗耳鸣的研究进展.《中华中医药学刊》.2009,第27卷(第3期),588-590.
马俊杰,朱萱萱.中医药治疗耳鸣的研究进展.《中华中医药学刊》.2009,第27卷(第3期),588-590. *

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