CN115364002B - Foundation liquid with acne removing effect and preparation method thereof - Google Patents
Foundation liquid with acne removing effect and preparation method thereof Download PDFInfo
- Publication number
- CN115364002B CN115364002B CN202211211642.7A CN202211211642A CN115364002B CN 115364002 B CN115364002 B CN 115364002B CN 202211211642 A CN202211211642 A CN 202211211642A CN 115364002 B CN115364002 B CN 115364002B
- Authority
- CN
- China
- Prior art keywords
- extract
- parts
- acne
- removing effect
- powder base
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 206010000496 acne Diseases 0.000 title claims abstract description 70
- 208000002874 Acne Vulgaris Diseases 0.000 title claims abstract description 68
- 230000000694 effects Effects 0.000 title claims abstract description 60
- 239000007788 liquid Substances 0.000 title claims abstract description 45
- 238000002360 preparation method Methods 0.000 title abstract description 23
- 150000001875 compounds Chemical class 0.000 claims abstract description 39
- 235000015112 vegetable and seed oil Nutrition 0.000 claims abstract description 39
- 239000008158 vegetable oil Substances 0.000 claims abstract description 39
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 36
- 230000003750 conditioning effect Effects 0.000 claims abstract description 20
- 239000000284 extract Substances 0.000 claims description 123
- 239000000243 solution Substances 0.000 claims description 46
- 238000003756 stirring Methods 0.000 claims description 31
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 24
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 23
- 238000001816 cooling Methods 0.000 claims description 22
- 239000011259 mixed solution Substances 0.000 claims description 20
- 239000000843 powder Substances 0.000 claims description 20
- 239000003921 oil Substances 0.000 claims description 19
- 239000002562 thickening agent Substances 0.000 claims description 19
- 238000000034 method Methods 0.000 claims description 18
- 235000019198 oils Nutrition 0.000 claims description 18
- 239000000419 plant extract Substances 0.000 claims description 15
- 239000003963 antioxidant agent Substances 0.000 claims description 14
- 230000003078 antioxidant effect Effects 0.000 claims description 14
- 239000003086 colorant Substances 0.000 claims description 14
- 239000003974 emollient agent Substances 0.000 claims description 14
- 239000003995 emulsifying agent Substances 0.000 claims description 14
- 239000003906 humectant Substances 0.000 claims description 14
- 238000000855 fermentation Methods 0.000 claims description 13
- 230000004151 fermentation Effects 0.000 claims description 13
- GTJOHISYCKPIMT-UHFFFAOYSA-N 2-methylundecane Chemical compound CCCCCCCCCC(C)C GTJOHISYCKPIMT-UHFFFAOYSA-N 0.000 claims description 12
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 claims description 12
- SGVYKUFIHHTIFL-UHFFFAOYSA-N Isobutylhexyl Natural products CCCCCCCC(C)C SGVYKUFIHHTIFL-UHFFFAOYSA-N 0.000 claims description 12
- 235000020691 dandelion extract Nutrition 0.000 claims description 12
- 229940067866 dandelion extract Drugs 0.000 claims description 12
- VKPSKYDESGTTFR-UHFFFAOYSA-N isododecane Natural products CC(C)(C)CC(C)CC(C)(C)C VKPSKYDESGTTFR-UHFFFAOYSA-N 0.000 claims description 12
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims description 12
- 239000001845 taraxacum officinale leaf extract Substances 0.000 claims description 12
- 239000008367 deionised water Substances 0.000 claims description 11
- 229910021641 deionized water Inorganic materials 0.000 claims description 11
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 10
- 235000013870 dimethyl polysiloxane Nutrition 0.000 claims description 10
- 238000010438 heat treatment Methods 0.000 claims description 10
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 10
- 210000000582 semen Anatomy 0.000 claims description 10
- 241000026010 Dendrobium candidum Species 0.000 claims description 8
- 244000164480 Curcuma aromatica Species 0.000 claims description 7
- 239000000945 filler Substances 0.000 claims description 7
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims description 6
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 claims description 6
- -1 polydimethylsiloxane Polymers 0.000 claims description 6
- 229940032094 squalane Drugs 0.000 claims description 6
- 239000012756 surface treatment agent Substances 0.000 claims description 6
- 239000010497 wheat germ oil Substances 0.000 claims description 6
- 235000003398 Curcuma aromatica Nutrition 0.000 claims description 5
- 241000180649 Panax notoginseng Species 0.000 claims description 5
- 235000003143 Panax notoginseng Nutrition 0.000 claims description 5
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims description 5
- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 5
- 230000001804 emulsifying effect Effects 0.000 claims description 5
- 235000008434 ginseng Nutrition 0.000 claims description 5
- 239000003755 preservative agent Substances 0.000 claims description 5
- 230000002335 preservative effect Effects 0.000 claims description 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 4
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 4
- 240000008042 Zea mays Species 0.000 claims description 4
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims description 4
- 229920006037 cross link polymer Polymers 0.000 claims description 4
- DTPCFIHYWYONMD-UHFFFAOYSA-N decaethylene glycol Chemical compound OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO DTPCFIHYWYONMD-UHFFFAOYSA-N 0.000 claims description 4
- 229940008099 dimethicone Drugs 0.000 claims description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 3
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims description 3
- 235000005822 corn Nutrition 0.000 claims description 3
- 238000000265 homogenisation Methods 0.000 claims description 3
- 239000004408 titanium dioxide Substances 0.000 claims description 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims description 2
- CUNWUEBNSZSNRX-RKGWDQTMSA-N (2r,3r,4r,5s)-hexane-1,2,3,4,5,6-hexol;(z)-octadec-9-enoic acid Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O CUNWUEBNSZSNRX-RKGWDQTMSA-N 0.000 claims description 2
- 229940015975 1,2-hexanediol Drugs 0.000 claims description 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical class CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 2
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 claims description 2
- SHOKSIZSCQFIRY-UHFFFAOYSA-N [3-(2-tert-butyl-2-hydroxy-4,4-dimethyl-3-phenylpentanoyl)oxy-2,2-bis[(2-tert-butyl-2-hydroxy-4,4-dimethyl-3-phenylpentanoyl)oxymethyl]propyl] 2-tert-butyl-2-hydroxy-4,4-dimethyl-3-phenylpentanoate Chemical compound C=1C=CC=CC=1C(C(C)(C)C)C(O)(C(C)(C)C)C(=O)OCC(COC(=O)C(O)(C(C=1C=CC=CC=1)C(C)(C)C)C(C)(C)C)(COC(=O)C(O)(C(C=1C=CC=CC=1)C(C)(C)C)C(C)(C)C)COC(=O)C(O)(C(C)(C)C)C(C(C)(C)C)C1=CC=CC=C1 SHOKSIZSCQFIRY-UHFFFAOYSA-N 0.000 claims description 2
- PGNYGWRFIFYBKV-UHFFFAOYSA-N [Mg].[Li].[Na] Chemical compound [Mg].[Li].[Na] PGNYGWRFIFYBKV-UHFFFAOYSA-N 0.000 claims description 2
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims description 2
- 229920001577 copolymer Polymers 0.000 claims description 2
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 claims description 2
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 claims description 2
- SZVJSHCCFOBDDC-UHFFFAOYSA-N ferrosoferric oxide Chemical compound O=[Fe]O[Fe]O[Fe]=O SZVJSHCCFOBDDC-UHFFFAOYSA-N 0.000 claims description 2
- FOYKKGHVWRFIBD-UHFFFAOYSA-N gamma-tocopherol acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 FOYKKGHVWRFIBD-UHFFFAOYSA-N 0.000 claims description 2
- 235000011187 glycerol Nutrition 0.000 claims description 2
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims description 2
- 229910052912 lithium silicate Inorganic materials 0.000 claims description 2
- 229910052943 magnesium sulfate Inorganic materials 0.000 claims description 2
- 235000019341 magnesium sulphate Nutrition 0.000 claims description 2
- MSRJTTSHWYDFIU-UHFFFAOYSA-N octyltriethoxysilane Chemical compound CCCCCCCC[Si](OCC)(OCC)OCC MSRJTTSHWYDFIU-UHFFFAOYSA-N 0.000 claims description 2
- 229960003493 octyltriethoxysilane Drugs 0.000 claims description 2
- 239000000377 silicon dioxide Substances 0.000 claims description 2
- FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 claims description 2
- 229960005078 sorbitan sesquioleate Drugs 0.000 claims description 2
- 235000019818 tetrasodium diphosphate Nutrition 0.000 claims description 2
- 238000004321 preservation Methods 0.000 claims 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims 1
- 241000208340 Araliaceae Species 0.000 claims 1
- 229940102552 disteardimonium hectorite Drugs 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 229940062000 polyglyceryl-2 triisostearate Drugs 0.000 claims 1
- 230000002829 reductive effect Effects 0.000 abstract description 11
- 206010061218 Inflammation Diseases 0.000 abstract description 8
- 230000004054 inflammatory process Effects 0.000 abstract description 8
- 230000003467 diminishing effect Effects 0.000 abstract description 7
- 230000002401 inhibitory effect Effects 0.000 abstract description 7
- 210000002374 sebum Anatomy 0.000 abstract description 7
- 241000894006 Bacteria Species 0.000 abstract description 6
- 230000002195 synergetic effect Effects 0.000 abstract description 6
- 230000028327 secretion Effects 0.000 abstract description 4
- 239000004480 active ingredient Substances 0.000 abstract description 3
- 230000003796 beauty Effects 0.000 abstract description 3
- 230000036074 healthy skin Effects 0.000 abstract description 3
- 239000012528 membrane Substances 0.000 abstract description 3
- 230000000474 nursing effect Effects 0.000 abstract description 3
- 239000000047 product Substances 0.000 description 16
- 239000000203 mixture Substances 0.000 description 15
- 238000012360 testing method Methods 0.000 description 12
- 244000131316 Panax pseudoginseng Species 0.000 description 9
- 244000269722 Thea sinensis Species 0.000 description 9
- 235000006708 antioxidants Nutrition 0.000 description 9
- 230000000052 comparative effect Effects 0.000 description 9
- 238000009472 formulation Methods 0.000 description 8
- 241000963390 Curcuma wenyujin Species 0.000 description 6
- 235000003394 Curcuma wenyujin Nutrition 0.000 description 6
- 241000186427 Cutibacterium acnes Species 0.000 description 6
- 229940055019 propionibacterium acne Drugs 0.000 description 6
- 241000132012 Atractylodes Species 0.000 description 5
- 241001313857 Bletilla striata Species 0.000 description 5
- 235000003181 Panax pseudoginseng Nutrition 0.000 description 5
- 235000020710 ginseng extract Nutrition 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 229940064064 purslane extract Drugs 0.000 description 5
- 239000000523 sample Substances 0.000 description 5
- 244000003416 Asparagus officinalis Species 0.000 description 4
- 235000005340 Asparagus officinalis Nutrition 0.000 description 4
- 240000007164 Salvia officinalis Species 0.000 description 4
- 239000013022 formulation composition Substances 0.000 description 4
- 230000002757 inflammatory effect Effects 0.000 description 4
- 230000005764 inhibitory process Effects 0.000 description 4
- 239000000498 cooling water Substances 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 239000000839 emulsion Substances 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 230000001815 facial effect Effects 0.000 description 3
- 239000011229 interlayer Substances 0.000 description 3
- 235000005412 red sage Nutrition 0.000 description 3
- 235000014375 Curcuma Nutrition 0.000 description 2
- 244000164418 Curcuma xanthorrhiza Species 0.000 description 2
- 235000003393 Curcuma xanthorrhiza Nutrition 0.000 description 2
- 241001523681 Dendrobium Species 0.000 description 2
- 241001076416 Dendrobium tosaense Species 0.000 description 2
- 108090001005 Interleukin-6 Proteins 0.000 description 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 239000001768 carboxy methyl cellulose Substances 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 235000005687 corn oil Nutrition 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000011534 incubation Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 229940112950 sage extract Drugs 0.000 description 2
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 2
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 2
- 239000006228 supernatant Substances 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- UUJLHYCIMQOUKC-UHFFFAOYSA-N trimethyl-[oxo(trimethylsilylperoxy)silyl]peroxysilane Chemical compound C[Si](C)(C)OO[Si](=O)OO[Si](C)(C)C UUJLHYCIMQOUKC-UHFFFAOYSA-N 0.000 description 2
- MZOFCQQQCNRIBI-VMXHOPILSA-N (3s)-4-[[(2s)-1-[[(2s)-1-[[(1s)-1-carboxy-2-hydroxyethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-[[2-[[(2s)-2,6-diaminohexanoyl]amino]acetyl]amino]-4-oxobutanoic acid Chemical compound OC[C@@H](C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)CCCCN MZOFCQQQCNRIBI-VMXHOPILSA-N 0.000 description 1
- ANZUDYZHSVGBRF-UHFFFAOYSA-N 3-ethylnonane-1,2,3-triol Chemical compound CCCCCCC(O)(CC)C(O)CO ANZUDYZHSVGBRF-UHFFFAOYSA-N 0.000 description 1
- GOZMBJCYMQQACI-UHFFFAOYSA-N 6,7-dimethyl-3-[[methyl-[2-[methyl-[[1-[3-(trifluoromethyl)phenyl]indol-3-yl]methyl]amino]ethyl]amino]methyl]chromen-4-one;dihydrochloride Chemical compound Cl.Cl.C=1OC2=CC(C)=C(C)C=C2C(=O)C=1CN(C)CCN(C)CC(C1=CC=CC=C11)=CN1C1=CC=CC(C(F)(F)F)=C1 GOZMBJCYMQQACI-UHFFFAOYSA-N 0.000 description 1
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 1
- 208000017667 Chronic Disease Diseases 0.000 description 1
- 244000163122 Curcuma domestica Species 0.000 description 1
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 description 1
- 238000008157 ELISA kit Methods 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 239000005913 Maltodextrin Substances 0.000 description 1
- 229920002774 Maltodextrin Polymers 0.000 description 1
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 description 1
- 235000017276 Salvia Nutrition 0.000 description 1
- 235000011135 Salvia miltiorrhiza Nutrition 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 description 1
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 description 1
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 description 1
- 241000588901 Zymomonas Species 0.000 description 1
- DFPAKSUCGFBDDF-ZQBYOMGUSA-N [14c]-nicotinamide Chemical compound N[14C](=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-ZQBYOMGUSA-N 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000003255 anti-acne Effects 0.000 description 1
- 239000000051 antiandrogen Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229960003237 betaine Drugs 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 229960001631 carbomer Drugs 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 230000001143 conditioned effect Effects 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 235000003373 curcuma longa Nutrition 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 description 1
- 229960003957 dexamethasone Drugs 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- OGQYPPBGSLZBEG-UHFFFAOYSA-N dimethyl(dioctadecyl)azanium Chemical compound CCCCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCCCC OGQYPPBGSLZBEG-UHFFFAOYSA-N 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- KWLMIXQRALPRBC-UHFFFAOYSA-L hectorite Chemical compound [Li+].[OH-].[OH-].[Na+].[Mg+2].O1[Si]2([O-])O[Si]1([O-])O[Si]([O-])(O1)O[Si]1([O-])O2 KWLMIXQRALPRBC-UHFFFAOYSA-L 0.000 description 1
- 229910000271 hectorite Inorganic materials 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 235000009973 maize Nutrition 0.000 description 1
- 229940035034 maltodextrin Drugs 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 229940101267 panthenol Drugs 0.000 description 1
- 239000011619 pantothenol Substances 0.000 description 1
- 235000020957 pantothenol Nutrition 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 244000132619 red sage Species 0.000 description 1
- 229930002330 retinoic acid Natural products 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 210000001732 sebaceous gland Anatomy 0.000 description 1
- 230000008591 skin barrier function Effects 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 229960001727 tretinoin Drugs 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/12—Face or body powders for grooming, adorning or absorbing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a foundation solution with acne removing effect and a preparation method thereof. According to the foundation liquid disclosed by the invention, the compound vegetable oil and the skin conditioning agent are added into the components, wherein the skin conditioning agent can condition the skin, excessive secretion of sebum is reduced, acne recurrence is prevented from root to root, the effective active ingredients in the compound vegetable oil can better penetrate through sebum membranes to play a role in resisting bacteria and diminishing inflammation, and the compound vegetable oil and the skin conditioning agent are mutually synergistic and mutually promoted in the effects of inhibiting bacteria and diminishing inflammation, so that the foundation liquid has an acne removing function, the skin is improved from inside to outside, and smooth and tender healthy skin is reduced, so that different nursing requirements of people loving beauty are met.
Description
Technical Field
The invention belongs to the technical field of cosmetics, and relates to a foundation liquid with an acne removing effect and a preparation method thereof.
Background
Acne, comedo, pimple and the like are commonly called acne in medicine, are common chronic diseases of sebaceous glands, and mainly occur in areas with vigorous sebum secretion such as faces, chest and back. At present, the modern medicine mainly uses androgen antagonists, antibiotics, retinoic acid medicines and the like to treat the disease, has a certain curative effect, but also has obvious side effects, so the market has great demands for acne-removing products.
The foundation liquid is a very important cosmetic product, is also the basis of good make-up effect, and has the main effects of bottoming and concealing the skin, covering facial flaws, homogenizing skin, endowing the skin with smooth and fine feeling, and in addition, the foundation liquid can prevent dust and the like in the air from entering the skin, so that the foundation liquid can play a role in protecting the skin, and the foundation liquid is directly smeared on the skin, so that important internal environment support is provided for various physiological functions of the skin, and meanwhile, the foundation liquid plays an important role in regulating the whole organism function.
CN111920706a provides a deep repairing foundation solution and a preparation method thereof, the deep repairing foundation solution is prepared from a formula a and a formula B, wherein the formula a comprises a first polar oil component, a second polar oil component, a stabilizer, titanium dioxide, iron oxide red and iron oxide yellow, and the formula B comprises xanthan gum, carbomer, a functional agent, nicotinamide, panthenol, betaine, a neutralizing agent, a preservative and water. The deep repairing foundation liquid not only can adjust skin color and cover flaws, but also has the characteristics of foundation liquid, and the skin has the effects of nature and uniform color.
CN109223597a discloses a make-up-holding foundation, comprising a film former comprising trimethylsiloxysilicate and sodium carboxymethyl cellulose. The foundation liquid is compounded by adding the oil phase and the water phase such as trimethylsiloxysilicate and sodium carboxymethyl cellulose, so that a 'two-phase film forming' technology is formed, a film formed by the foundation liquid can tightly lock toner, and meanwhile, the foundation liquid has double effects of water resistance and oil resistance, so that the migration resistance of the foundation liquid is improved.
The foundation solution only plays basic modification roles of concealing and changing skin color, has no acne-removing and skin-protecting effects, further cannot deeply care skin, has insufficient functionality, and therefore, development of the foundation solution with the acne-removing effects capable of concealing and changing skin color is urgently needed
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide a foundation liquid with acne removing effect and a preparation method thereof.
In order to achieve the aim of the invention, the invention adopts the following technical scheme:
in a first aspect, the invention provides a foundation solution with acne-removing effect, which comprises a humectant, an emollient, a film forming agent, an emulsifying agent, an antioxidant, a skin conditioner, a thickening agent, a colorant, compound vegetable oil, isododecane, ethanol and deionized water.
According to the foundation liquid disclosed by the invention, the compound vegetable oil and the skin conditioning agent are added into the components, wherein the skin conditioning agent can condition the skin, excessive secretion of sebum is reduced, acne recurrence is prevented from root to root, the effective active ingredients in the compound vegetable oil can better penetrate through sebum membranes to play a role in resisting bacteria and diminishing inflammation, and the compound vegetable oil and the skin conditioning agent are mutually synergistic and mutually promoted in the effects of inhibiting bacteria and diminishing inflammation, so that the foundation liquid has an acne removing function, the skin is improved from inside to outside, and smooth and tender healthy skin is reduced, so that different nursing requirements of people loving beauty are met.
The composition of the foundation solution with acne-removing effect comprises, by weight, 5-20 parts of humectant, 10-30 parts of emollient, 1-5 parts of film forming agent, 1-10 parts of emulsifier, 0.1-1 part of antioxidant, 0.1-1 part of skin conditioning agent, 1-3 parts of thickener, 5-15 parts of colorant, 1-10 parts of compound vegetable oil, 2-12 parts of isododecane, 1-3 parts of ethanol and deionized water;
preferably, the composition of the foundation solution with acne removing effect comprises the following components in parts by weight:
5-20 parts of humectant, for example, 6 parts, 8 parts, 10 parts, 12 parts, 14 parts, 15 parts, 17 parts or 19 parts, etc.;
10 to 30 parts of an emollient, for example, 12 parts, 15 parts, 17 parts, 19 parts, 20 parts, 22 parts, 25 parts, 27 parts, 29 parts, or the like;
1 to 5 parts of film forming agent, for example, 1 part, 1.5 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts or 4.5 parts, etc.;
1-10 parts of emulsifier, for example, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts or 10 parts, etc.;
0.1 to 1 part of antioxidant, for example, 0.2 part, 0.3 part, 0.4 part, 0.5 part, 0.6 part, 0.7 part, 0.8 part or 0.9 part, etc.;
0.1 to 1 part of skin conditioning agent, for example, 0.2 part, 0.3 part, 0.4 part, 0.5 part, 0.6 part, 0.7 part, 0.8 part or 0.9 part, etc.;
1 to 3 parts of thickener, for example, 1.2 parts, 1.5 parts, 1.8 parts, 2 parts, 2.2 parts, 2.5 parts, 2.6 parts or 2.8 parts, etc.;
5 to 15 parts of a colorant, for example, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, 14 parts, or the like;
1-10 parts of compound vegetable oil, for example, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts or 10 parts and the like;
2 to 12 parts of isododecane, for example, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts or the like;
the ethanol may be 1.2 parts, 1.5 parts, 1.8 parts, 2 parts, 2.2 parts, 2.5 parts, or 2.8 parts, for example.
Specific point values within the above numerical ranges are all selectable, and will not be described in detail herein.
Preferably, the composition of the foundation solution with acne-removing effect comprises, by weight, 10-18 parts of humectant, 15-25 parts of emollient, 2-4 parts of film forming agent, 2-8 parts of emulsifier, 0.3-0.8 part of antioxidant, 0.3-1 part of skin conditioning agent, 1.5-2 parts of thickener, 7-12 parts of colorant, 5-8 parts of compound vegetable oil, 5-10 parts of isododecane, 2-3 parts of ethanol and deionized water.
Preferably, the humectant comprises any one or a combination of at least two of glycerin, butylene glycol, dipropylene glycol or 1, 2-hexanediol.
Preferably, the emollient comprises any one or a combination of at least two of cyclopentadimethicone, dimethicone, polyglycerol-2 triisostearate, or dimethicone crosspolymer.
Preferably, the antioxidant comprises pentaerythritol tetrakis (di-tert-butylhydroxyhydrocinnamate) and/or tocopheryl acetate.
Preferably, the film former comprises an acrylic/trimethicone methacrylate copolymer.
Preferably, the emulsifier comprises any one or a combination of at least two of PEG-10 polydimethylsiloxane, PEG/PPG-18/18 polydimethylsiloxane, sorbitan sesquioleate, hydrogenated lecithin or polydimethylsiloxane PEG-10/15 crosslinked polymer.
Preferably, the skin conditioner comprises any one or a combination of at least two of ethylhexyl glycerol, fermented monospore fermentation product extract, curcuma xanthorrhiza extract, curcuma wenyujin extract, maltodextrin or honey extract.
Preferably, the skin conditioner is a combination of a zymomonas fermentation product extract, a curzedoary extract and a curcuma wenyujin extract.
Preferably, the mass ratio of the fermentation product extract of the fermentation monospora, the extract of the curcuma longa and the extract of the curcuma wenyujin is 1 (1-5) (0.1-0.2).
For example, the values may be 1:1:0.1, 1:1:0.2, 1:2:0.1, 1:2:0.2, 1:3:0.1, 1:4:0.2, or 1:5:0.2, and the specific values within the above numerical ranges may be selected, and will not be described in detail herein.
The invention creatively discovers that the fermentation product extract of the fermentation monospora, the extract of the curcuma aromatica and the extract of the curcuma wenyujin have synergistic effect in the aspects of regulating microbial flora, relieving skin and enhancing skin barrier, and the quality ratio is in the range, so that the effect is better.
Preferably, the thickener comprises any one or a combination of at least two of tetrasodium pyrophosphate, magnesium sulfate, distearyldimethylammonium hectorite or sodium magnesium lithium silicate.
Preferably, the colorant comprises any one or a combination of at least two of iron oxide red, aluminum hydroxide, titanium dioxide, iron oxide yellow or iron oxide black.
Preferably, the components of the compound vegetable oil comprise squalane, wheat germ oil, corn germ oil, dendrobium extract and dandelion extract.
According to the compound vegetable oil, three oily substances of squalane, wheat germ oil and corn germ oil are matched with the dendrobium officinale extract and the dandelion extract, so that water-oil balance can be conditioned, inflammation and sterilization can be realized, pores are unblocked, and healing is restored, so that an acne removing effect is achieved.
Preferably, the compound vegetable oil comprises 50-70% of squalane, 15-25% of wheat germ oil, 10-20% of corn germ oil, 0.1-0.2% of dendrobium candidum extract and 0.1-0.2% of dandelion extract by mass percent.
Wherein the mass percent of squalane can be 52%, 54%, 56%, 58%, 60%, 62%, 64%, 65%, 66% or 68%, etc.;
the mass percentage of the wheat germ oil can be 16%, 17%, 18%, 19%, 20%, 21%, 22%, 23%, 24% or 25%, etc.;
the mass percentage of the maize germ oil can be 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19% or 20%, etc.;
the mass percentage of the dendrobium candidum extract can be 0.11%, 0.12%, 0.13%, 0.14%, 0.15%, 0.16%, 0.17%, 0.18% or 0.19%, etc.;
the mass percentage of dandelion extract can be 0.11%, 0.12%, 0.13%, 0.14%, 0.15%, 0.16%, 0.17%, 0.18% or 0.19%.
Preferably, the compound vegetable oil further comprises 0.1-0.2% of other plant extracts by mass percent, for example, 0.11%, 0.12%, 0.13%, 0.14%, 0.15%, 0.16%, 0.17%, 0.18% or 0.19% and the like.
Preferably, the other plant extracts comprise any one or a combination of at least two of pseudo-ginseng extract, red sage extract, ginseng extract, asparagus extract, bletilla striata extract, bighead atractylodes rhizome extract, tea extract, semen cuscutae extract and purslane extract;
preferably, the other plant extract is a combination of Notoginseng radix extract, saviae Miltiorrhizae radix extract, ginseng radix extract, radix asparagi extract, rhizoma Bletillae extract, atractylodis rhizoma extract, tea extract, semen Cuscutae extract and herba Portulacae extract.
Preferably, the compound vegetable oil is a combination of squalane, wheat germ oil, corn germ oil, dendrobium extract, dandelion extract, pseudo-ginseng extract, red sage extract, ginseng extract, asparagus extract, bletilla striata extract, bighead atractylodes rhizome extract, tea extract, semen cuscutae extract and purslane extract.
According to the preferable technical scheme, the pseudo-ginseng extract, the tea extract and the purslane extract are added into the compound vegetable oil, so that the effects of clearing heat and detoxicating, diminishing inflammation, resisting allergy and controlling oil are improved, the anti-inflammatory and acne-removing effects are excellent, meanwhile, the ginseng extract, the red-rooted salvia root extract, the white atractylodes rhizome extract and the bletilla striata extract are added, acne is removed, meanwhile, color marks are eliminated, skin is whitened, and the application of the radix asparagi extract and the semen cuscutae extract can effectively whiten the skin and keep the moisture content of the skin.
Preferably, the foundation solution with acne removing effect further comprises any one or a combination of at least two of a toner surface treatment agent, a filler or a preservative.
Preferably, the toner surface treatment agent includes triethoxy octyl silane.
Preferably, the preservative comprises octylglycol.
Preferably, the filler comprises silica.
In a second aspect, the present invention provides a method for preparing a powder base solution with acne removing effect according to the first aspect, where the method for preparing the powder base solution with acne removing effect includes:
1) Adding the humectant, part of thickener and deionized water into a water phase pot, heating and stirring, and preserving heat after dissolving to obtain a mixed solution A;
adding an emulsifier, an emollient, an antioxidant, a film forming agent, ethanol and isododecane into an oil phase pot, heating and stirring to obtain a mixed solution B;
2) Adding the mixed solution A and the mixed solution B into an emulsifying pot, and stirring and homogenizing for the first time; cooling the feed liquid, adding a skin conditioning agent and the rest of thickening agent, and stirring and homogenizing for the second time;
3) Continuously cooling, then adding the coloring agent, stirring and homogenizing;
4) Continuously cooling, adding the compound vegetable oil, stirring and homogenizing, cooling and standing to obtain the powder base solution with the acne removing effect.
Preferably, the temperature of heating in the water phase pot in step (1) is 85-90 ℃ (for example, 85 ℃, 86 ℃, 87 ℃, 88 ℃, 89 ℃, 90 ℃ and the like) and the time is 5-10min (for example, 6min, 7min, 8min or 9min and the like).
Preferably, the temperature of the incubation in step (1) is 80-85deg.C (e.g., 80deg.C, 1608C, 83deg.C, 84deg.C, 85deg.C, etc.), and the incubation time is 10-20min (e.g., 12min, 14min, 15min, 16min, 18min, etc.).
Preferably, the heating temperature in the oil phase pot in the step (1) is 80-85 ℃ (for example, the heating temperature can be 80 ℃, 81 ℃, 82 ℃,83 ℃, 84 ℃,85 ℃ and the like) and the heating time is 5-20min (for example, the heating time can be 6min, 8min, 10min, 13min, 15min, 17min or 19min and the like).
Preferably, the first stirring homogenizing time in step (2) is 8-10min (e.g., 8min, 8.5min, 9min, 9.5min, 10min, etc.), and the temperature is 80-85deg.C (e.g., 80deg.C, 81 deg.C, 82 deg.C, 83 deg.C, 84 deg.C, 85 deg.C, etc.).
Preferably, the second stirring homogenization time of step (2) is 2-5min (e.g., may be 2.5min, 3min, 3.5min, 4min, 4.5min, etc.).
Preferably, the temperature of the step (2) is reduced to 60-65 ℃ (for example, 60 ℃, 61 ℃, 62 ℃, 63 ℃, 64 ℃, 65 ℃ and the like can be obtained).
Preferably, the temperature of the step (3) is reduced to 45-50deg.C (for example, 45 deg.C, 46 deg.C, 47 deg.C, 48 deg.C, 49 deg.C, 50 deg.C, etc.).
Preferably, the homogenizing time of step (3) is 5-10min (e.g., may be 5min, 6min, 7min, 8min, 9min, 10min, etc.).
Preferably, the temperature of the step (4) is reduced to 35-40deg.C (such as 35deg.C, 36deg.C, 37deg.C, 38deg.C, 39deg.C, 40deg.C, etc.).
Preferably, the homogenization time in step (4) is 5-10min (e.g., may be 5min, 6min, 7min, 8min, 9min, 10min, etc.).
Preferably, the cooling in step (4) is carried out to 25-30deg.C (for example, 25 ℃, 26 ℃, 27 ℃, 28 ℃, 29 ℃, 30 ℃ and the like may be carried out).
Preferably, the rest time in step (4) is 24-30h (e.g. 25h, 26h, 27h, 28h, 29h, etc.).
Compared with the prior art, the invention has the following beneficial effects:
according to the foundation liquid disclosed by the invention, the compound vegetable oil and the skin conditioning agent are added into the components, wherein the skin conditioning agent can condition the skin, excessive secretion of sebum is reduced, acne recurrence is prevented from root to root, the effective active ingredients in the compound vegetable oil can better penetrate through sebum membranes to play a role in resisting bacteria and diminishing inflammation, and the compound vegetable oil and the skin conditioning agent are mutually synergistic and mutually promoted in the effects of inhibiting bacteria and diminishing inflammation, so that the foundation liquid has an acne removing function, the skin is improved from inside to outside, and smooth and tender healthy skin is reduced, so that different nursing requirements of people loving beauty are met.
Detailed Description
The technical scheme of the invention is further described by the following specific embodiments. It will be apparent to those skilled in the art that the examples are merely to aid in understanding the invention and are not to be construed as a specific limitation thereof.
The partial material information related to examples and comparative examples is as follows:
in addition, dendrobium officinale extract, dandelion extract, curcuma xanthorrhiza extract, curcuma wenyujin extract, pseudo-ginseng extract, salvia miltiorrhiza extract, ginseng extract, asparagus root extract, bletilla striata extract, bighead atractylodes rhizome extract, tea extract, semen cuscutae extract and purslane extract are all purchased from Anhui de Zhengtang pharmaceutical industry.
Other materials may be used as long as they are commercially available through regular channels.
Example 1
The embodiment provides a foundation solution with acne-removing effect, which comprises the following components in parts by weight:
the other plant extracts are the combination of Notoginseng radix extract, saviae Miltiorrhizae radix extract, ginseng radix extract, radix asparagi extract, rhizoma Bletillae extract, atractylodis rhizoma extract, tea extract, semen Cuscutae extract and herba Portulacae extract with equal quality.
The preparation method of the foundation solution with acne removing effect comprises the following steps:
(1) Adding humectant, 2/3 of thickener and deionized water into a water phase pot according to the formula amount, stirring for 8min at 85 ℃, and preserving heat for 10min at 80 ℃ after dissolving to obtain a mixed solution A;
adding an emulsifier, an emollient, an antioxidant, a film forming agent, ethanol and isododecane into an oil phase pot according to the formula amount, and stirring at 80 ℃ for 15min until the mixture is dissolved to obtain a mixed solution B;
(2) Adding the mixed solution A and the mixed solution B into an emulsifying pot, and homogenizing for 10 minutes at 80 ℃ to form uniform and stable emulsion; opening interlayer cooling water to reduce the temperature of the material to 60 ℃, adding a skin conditioning agent, a toner surface treatment agent and the rest thickener, and homogenizing and stirring for 3 minutes;
(3) Continuously cooling to 45 ℃, adding the coloring agent and the filler, stirring and homogenizing for 8min;
(4) Continuously cooling to 40 ℃, adding the compound vegetable oil, stirring and homogenizing for 5 minutes, cooling to 25 ℃, and then standing for 24 hours to obtain the foundation liquid.
Example 2
The embodiment provides a foundation solution with acne-removing effect, which comprises the following components in parts by weight:
the other plant extracts are the combination of Notoginseng radix extract, saviae Miltiorrhizae radix extract, ginseng radix extract, radix asparagi extract, rhizoma Bletillae extract, atractylodis rhizoma extract, tea extract, semen Cuscutae extract and herba Portulacae extract with equal quality.
The preparation method of the foundation solution with acne removing effect comprises the following steps:
(1) Adding humectant, 2/3 of thickener and deionized water into a water phase pot according to the formula amount, stirring for 8min at 90 ℃, and preserving heat for 15min at 85 ℃ after dissolving to obtain a mixed solution A;
adding an emulsifier, an emollient, an antioxidant, a film forming agent, ethanol and isododecane into an oil phase pot according to the formula amount, and stirring for 15min at 85 ℃ until the mixture is dissolved to obtain a mixed solution B;
(2) Adding the mixed solution A and the mixed solution B into an emulsifying pot, and homogenizing at 85 ℃ for 8 minutes to form uniform and stable emulsion; opening interlayer cooling water to reduce the temperature of the material to 60 ℃, adding a skin conditioning agent, a toner surface treatment agent and the rest thickener, and homogenizing and stirring for 5 minutes;
(3) Continuously cooling to 50 ℃, adding the coloring agent and the filler, stirring and homogenizing for 10min;
(4) Continuously cooling to 38 ℃, adding the compound vegetable oil, stirring and homogenizing for 10 minutes, cooling to 30 ℃, and then standing for 30 hours to obtain the foundation liquid.
Example 3
The embodiment provides a foundation solution with acne-removing effect, which comprises the following components in parts by weight:
the other plant extracts are the combination of Notoginseng radix extract, saviae Miltiorrhizae radix extract, ginseng radix extract, radix asparagi extract, rhizoma Bletillae extract, atractylodis rhizoma extract, tea extract, semen Cuscutae extract and herba Portulacae extract with equal quality.
The preparation method of the foundation solution with acne removing effect comprises the following steps:
(1) Adding humectant, 2/3 of thickener and deionized water into a water phase pot according to the formula amount, stirring for 10min at 88 ℃, and preserving heat for 15min at 84 ℃ after dissolving to obtain a mixed solution A;
adding an emulsifier, an emollient, an antioxidant, a film forming agent, ethanol and isododecane into an oil phase pot according to the formula amount, and stirring for 15min at 83 ℃ until the mixture is dissolved to obtain a mixed solution B;
(2) Adding the mixed solution A and the mixed solution B into an emulsifying pot, and homogenizing for 10 minutes at 83 ℃ to form uniform and stable emulsion; opening interlayer cooling water to reduce the temperature of the material to 62 ℃, adding a skin conditioning agent, a toner surface treatment agent and the rest thickener, and homogenizing and stirring for 2 minutes;
(3) Continuously cooling to 42 ℃, adding the coloring agent and the filler, stirring and homogenizing for 8min;
(4) Continuously cooling to 35 ℃, adding the compound vegetable oil, stirring and homogenizing for 7 minutes, cooling to 28 ℃, and then standing for 28 hours to obtain the foundation liquid.
Example 4
The formulation of the foundation solution is different from that of the embodiment 1 only in that the skin conditioner comprises the curcuma guangxi extract and the curcuma wenyujin extract in a mass ratio of 15:1 in parts by weight, the addition amount of the skin conditioner is kept unchanged, and the rest components are kept unchanged, and the preparation method is as shown in the embodiment 1.
Example 5
The formulation of the foundation solution is different from that of the embodiment 1 only in that the skin conditioner comprises the fermented monospore fermentation product extract and the radix curcumae extract in a mass ratio of 5:1 in parts by weight, the addition amount of the skin conditioner is kept unchanged, and the rest components are kept unchanged, and the preparation method is as shown in the embodiment 1.
Example 6
The formulation of the foundation solution is different from that of the embodiment 1 only in that the skin conditioner comprises the fermentation product extract of the fermentation monospore and the extract of the curcuma Guangxi, in parts by weight, of which the mass ratio is 1:3, and the addition amount of the skin conditioner is kept unchanged, and the rest components are kept unchanged, and the preparation method is as shown in the embodiment 1.
Example 7
The formulation of the foundation solution is different from that of the embodiment 1 only in that the components of the compound vegetable oil do not comprise other plant extracts, and the other components remain unchanged, and the preparation method refers to the embodiment 1.
Example 8
The formulation of the foundation solution is different from that of the embodiment 1 only in that the components of the compound vegetable oil do not comprise dandelion extract and dendrobium candidum extract, and the rest components are kept unchanged, and the preparation method refers to the embodiment 1.
Example 9
The formulation of the foundation solution is different from that of the embodiment 1 only in that the compound vegetable oil does not comprise dandelion extract, the adding amount of dendrobium candidum extract is 0.02 part, and the rest components are kept unchanged, and the preparation method is as shown in the embodiment 1.
Example 10
The formulation of the foundation solution is different from that of the embodiment 1 only in that the compound vegetable oil does not comprise dendrobium candidum extract, the adding amount of dandelion extract is 0.02 part, and the rest components are kept unchanged, and the preparation method is as shown in the embodiment 1.
Example 11
The present example provides a foundation solution with acne-removing effect, which is different from example 1 in the formulation composition only in that herba centellae extract is used to replace herba Dendrobii extract, and the addition amount of herba centellae extract is maintained to be 0.012 parts, and the remaining components are maintained, and the preparation method is described in example 1.
Example 12
The present example provides a foundation solution with acne-removing effect, which is different from example 1 in the formulation composition only in that herba Centellae extract is used instead of herba Taraxaci extract, and the addition amount of herba Centellae extract is maintained at 0.008 parts, and the rest components are maintained unchanged, and the preparation method is described in example 1.
Example 13
The formulation composition of the foundation solution is different from that of the embodiment 1 only in that the other plant extracts are the combination of the ginseng extract, the asparagus extract, the bletilla striata extract, the bighead atractylodes rhizome extract and the purslane extract, the addition amount of the other plant extracts is kept unchanged, and the other components are kept unchanged, so that the preparation method is as shown in the embodiment 1.
Example 14
The formulation of the foundation solution is different from that of the embodiment 1 only in that the other plant extracts are the combination of the pseudo-ginseng extract, the red sage root extract, the tea extract and the semen cuscutae extract, the addition amount of the other plant extracts is kept unchanged, and the other components are kept unchanged, so that the preparation method is described in the embodiment 1.
Comparative example 1
This comparative example provides a foundation solution with acne-removing effect, which is different from example 1 in the formulation composition only in that no skin conditioner is contained, the remaining components remain unchanged, and the preparation method is described in example 1.
Comparative example 2
The comparative example provides a foundation solution with acne-removing effect, the composition of the foundation solution is different from that of example 1 only in that the foundation solution does not contain compound vegetable oil, the rest components are unchanged, and the preparation method is described in example 1.
Test example 1
Detection of minimum inhibitory concentration of propionibacterium acnes:
the product of example 1 was prepared as a 100mg/mL sample, ten test tubes (the first empty tube, the remaining nine being filled with 5mL distilled water) were prepared, and 5mL of sample was added to the first test tube; then sucking 5mL of sample, adding the sample into a second test tube, and uniformly mixing; then 5mL of the dilution was aspirated into a third tube and so on, by the tenth, 5mL was aspirated in the tenth tube for disposal. To ten test tubes, 0.1mL of Propionibacterium acnes (100000 cfu/mL) was added, mixed well, placed in an incubator at 37℃for 24h, the clear test tubes were observed, and the MIC of the minimum inhibitory concentration was determined.
The operations of examples 2-14 and comparative examples 1-2 were as above and the results are shown in Table 1:
TABLE 1
As can be seen from the data in table 1: the foundation solution has remarkable inhibition effect on propionibacterium acnes, wherein the compound vegetable oil and the skin conditioner have synergistic effect in the aspect of inhibiting the propionibacterium acnes, and the foundation solution has better inhibition effect on the propionibacterium acnes when dandelion extract, dendrobium candidum extract and other plant extracts exist in the compound vegetable oil.
Test example 2
Detection of anti-inflammatory action on inflammatory factors:
(1) Raw264.7 cells in good culture were diluted to a concentration of 1X 10 5 cfu/mL；
(2) 12 well cell plates were prepared at a concentration of 1X 10 5 cfu/mL Raw264.7 cells were transferred to 12-well plates with a pipette, 1mL was added to each well, and cultured at 37℃for 24 hours;
(3) The test consisted of 21 groups, blank (no sample added), LPS (1. Mu.g/mL LPS added), test (sample solutions of examples 1-14 and comparative examples 1-2 with a concentration of 2mg/mL LPS containing 1. Mu.g/mL added), positive control (0.1 mg/mL dexamethasone added). Discarding the supernatant of the Raw264.7 cell culture solution, adding the corresponding solutions of each group, and culturing for 24 hours at 37 ℃;
(4) The supernatant was centrifuged and the concentrations of inflammatory factors TNF- α and IL-6 were measured according to the test procedure on ELISA kit, and each group was assayed 5 times in parallel and averaged.
The results are shown in Table 2:
TABLE 2
As can be seen from the data in table 2: the foundation liquid has very remarkable inhibition effect on inflammatory factors TNF-alpha and IL-6, wherein the compound vegetable oil and the skin conditioner have synergistic effect in inhibiting propionibacterium acnes, and the foundation liquid has better inhibition effect on inflammatory factors when dandelion extract, dendrobium candidum extract and other plant extracts exist in the compound vegetable oil.
Test example 3
160 volunteers with acne on the face aged 25-45 years were selected and randomly divided into 16 groups of 10 volunteers, and 16 groups of volunteers were subjected to acne removal and mildness evaluation by using the products of examples 1-14 and comparative examples 1-2, respectively.
The test method comprises the following steps: the subjects cleaned their faces using an alkaline soap-based cleaning product under the direction of the staff, and after cleaning were wiped clean with a chipless absorbent dry paper towel. The initial acne on the face of each group of subjects was counted by laboratory researchers during periods of no water or beverage consumption when sitting still in the satisfactory room for at least 30 minutes. Subjects used the product 1 time after facial cleansing in the morning and returned to the laboratory after the 10 th and 20 th days of use of the product, under the same test conditions, the subjects were counted for facial acne by laboratory researchers, and the volunteers performed a mildness evaluation of the product at 20 th day, with the following scoring criteria and grades:
the acne removal test results and the mildness evaluation results are shown in table 3 (all data presented as average):
TABLE 3 Table 3
As can be seen from the data in table 3: the foundation liquid has no stimulation to skin, which proves that the product is safer and milder; the data of examples 1-3 show that the foundation liquid has remarkable acne removing effect, and the acne reducing rate can reach more than 40% after 20 days of use; examples 4 to 6 show that when the skin conditioner is not the type selected in the present invention, the acne removing effect of the foundation liquid is reduced; examples 7-14 show that the components of the compound vegetable oil also affect the acne-removing effect of the foundation solution; as can be seen from comparative examples 1 and 2, when the skin conditioner or the compound vegetable oil is absent in the foundation solution of the present application, the acne removing effect of the foundation solution is greatly reduced.
The applicant states that the foundation liquid with acne removing effect and the preparation method thereof are described by the above examples, but the invention is not limited to the above detailed method, i.e. the invention must not depend on the above detailed method to be implemented. It should be apparent to those skilled in the art that any modification of the present invention, equivalent substitution of raw materials for the product of the present invention, addition of auxiliary components, selection of specific modes, etc., falls within the scope of the present invention and the scope of disclosure.
Claims (27)
1. The foundation solution with the acne-removing effect is characterized by comprising the components of a humectant, an emollient, a film forming agent, an emulsifying agent, an antioxidant, a skin conditioning agent, a thickening agent, a coloring agent, compound vegetable oil, isododecane, ethanol and deionized water;
the skin conditioner is a combination of a fermentation product extract of the fermentation mono-spore, a curcuma aromatica extract and a curcuma aromatica extract, wherein the mass ratio of the fermentation product extract of the fermentation mono-spore, the curcuma aromatica extract of the Guangxi and the curcuma aromatica extract is 1 (1-5) (0.1-0.2);
the compound vegetable oil comprises, by mass, 56-70% of squalane, 15-25% of wheat germ oil, 10-20% of corn germ oil, 0.1-0.2% of dendrobium candidum extract, 0.1-0.2% of dandelion extract and 0.1-0.2% of other plant extracts;
the other plant extracts are the combination of Notoginseng radix extract, saviae Miltiorrhizae radix extract, ginseng radix extract, radix asparagi extract, rhizoma Bletillae extract, atractylodis rhizoma extract, folium Camelliae sinensis extract, semen Cuscutae extract and herba Portulacae extract.
2. The powder base solution with acne removing effect according to claim 1, wherein the powder base solution with acne removing effect comprises, by weight, 5-20 parts of humectant, 10-30 parts of emollient, 1-5 parts of film forming agent, 1-10 parts of emulsifying agent, 0.1-1 part of antioxidant, 0.1-1 part of skin conditioning agent, 1-3 parts of thickening agent, 5-15 parts of coloring agent, 1-10 parts of compound vegetable oil, 2-12 parts of isododecane, 1-3 parts of ethanol and deionized water.
3. The powder base liquid with acne removing effect according to claim 2, wherein the powder base liquid with acne removing effect comprises, by weight, 10-18 parts of humectant, 15-25 parts of emollient, 2-4 parts of film forming agent, 2-8 parts of emulsifying agent, 0.3-0.8 part of antioxidant, 0.3-1 part of skin conditioning agent, 1.5-2 parts of thickening agent, 7-12 parts of coloring agent, 5-8 parts of compound vegetable oil, 5-10 parts of isododecane, 2-3 parts of ethanol and deionized water.
4. The powder base liquid with acne removing effect according to claim 1, wherein the humectant comprises any one or a combination of at least two of glycerin, butylene glycol, dipropylene glycol or 1, 2-hexanediol.
5. The powder base fluid with acne efficacy according to claim 1, wherein the emollient comprises any one or a combination of at least two of cyclopentadimethicone, dimethicone, polyglyceryl-2 triisostearate, or dimethicone crosspolymer.
6. The powder base liquid with acne-removing effect according to claim 1, wherein the antioxidant comprises pentaerythritol tetra (di-t-butylhydroxyhydrocinnamate) and/or tocopheryl acetate.
7. The powder base liquid with acne removing effect according to claim 1, wherein the film forming agent comprises acrylic acid (ester)/poly (trimethylsiloxane) methacrylate copolymer.
8. The powder base liquid with acne removing effect according to claim 1, wherein the emulsifier comprises any one or a combination of at least two of PEG-10 polydimethylsiloxane, PEG/PPG-18/18 polydimethylsiloxane, sorbitan sesquioleate, hydrogenated lecithin or polydimethylsiloxane PEG-10/15 cross-linked polymer.
9. The powder base liquid with acne removing effect according to claim 1, wherein the thickener comprises any one or a combination of at least two of tetrasodium pyrophosphate, magnesium sulfate, disteardimonium hectorite, or sodium magnesium lithium silicate.
10. The powder base liquid with acne efficacy according to claim 1, wherein the colorant comprises any one or a combination of at least two of iron oxide red, aluminum hydroxide, titanium dioxide, iron oxide yellow or iron oxide black.
11. The acne-removing foundation liquid of claim 1, wherein the acne-removing foundation liquid further comprises any one or a combination of at least two of a toner surface treatment agent, a filler, or a preservative.
12. The powder base liquid with acne removing effect according to claim 11, wherein the toner surface treating agent comprises triethoxy octyl silane.
13. The powder base liquid with acne removing effect according to claim 11, wherein the preservative comprises octylglycol.
14. The powder base liquid with acne efficacy according to claim 11, wherein the filler comprises silica.
15. The method for preparing a powder base solution with acne efficacy according to any one of claims 1 to 14, wherein the method for preparing a powder base solution with acne efficacy comprises the following steps:
1) Adding the humectant, part of thickener and deionized water into a water phase pot, heating and stirring, and preserving heat after dissolving to obtain a mixed solution A;
adding an emulsifier, an emollient, an antioxidant, a film forming agent, ethanol and isododecane into an oil phase pot, heating and stirring to obtain a mixed solution B;
2) Adding the mixed solution A and the mixed solution B into an emulsifying pot, and stirring and homogenizing for the first time; cooling the feed liquid, adding a skin conditioning agent and the rest of thickening agent, and stirring and homogenizing for the second time;
3) Continuously cooling, then adding the coloring agent, stirring and homogenizing;
4) Continuously cooling, adding the compound vegetable oil, stirring and homogenizing, cooling and standing to obtain the powder base solution with the acne removing effect.
16. The process of claim 15, wherein the water phase in step (1) is heated at a temperature of 85-90 ℃ for a period of 5-10 minutes.
17. The method according to claim 15, wherein the temperature of the heat preservation in the step (1) is 80-85 ℃ and the heat preservation time is 10-20min.
18. The method of claim 15, wherein the heating in the oil phase pot of step (1) is at a temperature of 80-85 ℃ for a period of 5-20min.
19. The method of claim 15, wherein the first stirring and homogenizing step (2) is carried out for 8-10min at 80-85deg.C.
20. The method of claim 15, wherein the second stirring homogenization time of step (2) is 2-5 minutes.
21. The method of claim 15, wherein the cooling in step (2) is to 60-65 ℃.
22. The method of claim 15, wherein the cooling in step (3) is to 45-50 ℃.
23. The method of claim 15, wherein the homogenizing in step (3) is performed for a period of 5 to 10 minutes.
24. The method of claim 15, wherein the cooling in step (4) is to 35-40 ℃.
25. The method of claim 15, wherein the homogenizing time in step (4) is 5-10min.
26. The method of claim 15, wherein the cooling in step (4) is to 25-30 ℃.
27. The method according to claim 15, wherein the standing time in the step (4) is 24 to 30 hours.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211211642.7A CN115364002B (en) | 2022-09-30 | 2022-09-30 | Foundation liquid with acne removing effect and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211211642.7A CN115364002B (en) | 2022-09-30 | 2022-09-30 | Foundation liquid with acne removing effect and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN115364002A CN115364002A (en) | 2022-11-22 |
| CN115364002B true CN115364002B (en) | 2024-04-12 |
Family
ID=84072712
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211211642.7A Active CN115364002B (en) | 2022-09-30 | 2022-09-30 | Foundation liquid with acne removing effect and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115364002B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3151216A1 (en) | 2023-07-23 | 2025-01-24 | Le Rouge Francais | Cosmetic composition with particular coloring ingredient of plant origin and particular fatty substances of plant origin and particular isoalkane. |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20100100455A (en) * | 2009-03-06 | 2010-09-15 | 한국콜마 주식회사 | Curcuma wenyujin essential oil having anti-dermatophytosis activity and cosmetic components comprised of it |
| CN110368348A (en) * | 2019-08-29 | 2019-10-25 | 广州重生化妆品实业有限公司 | A kind of formula of acne removal stock liquid and preparation method thereof |
| CN111110619A (en) * | 2020-02-14 | 2020-05-08 | 广州市科能化妆品科研有限公司 | Oil-control acne-removing composition and application thereof in cosmetics |
| CN111419739A (en) * | 2020-04-09 | 2020-07-17 | 丽鑫生技化妆品（上海）有限公司 | Cool air cushion foundation and preparation method thereof |
| CN113712873A (en) * | 2021-09-26 | 2021-11-30 | 湖北省麦诗特生物科技有限公司 | Essence emulsion composition with acne-removing and anti-inflammatory effects and preparation method thereof |
| CN114767603A (en) * | 2022-03-11 | 2022-07-22 | 彭氏(惠州)实业发展有限公司 | Acne-removing cosmetic composition containing red ginseng extract |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168478A (en) * | 2015-08-28 | 2015-12-23 | 无限极（中国）有限公司 | Skin care product and preparation method thereof |
-
2022
- 2022-09-30 CN CN202211211642.7A patent/CN115364002B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20100100455A (en) * | 2009-03-06 | 2010-09-15 | 한국콜마 주식회사 | Curcuma wenyujin essential oil having anti-dermatophytosis activity and cosmetic components comprised of it |
| CN110368348A (en) * | 2019-08-29 | 2019-10-25 | 广州重生化妆品实业有限公司 | A kind of formula of acne removal stock liquid and preparation method thereof |
| CN111110619A (en) * | 2020-02-14 | 2020-05-08 | 广州市科能化妆品科研有限公司 | Oil-control acne-removing composition and application thereof in cosmetics |
| CN111419739A (en) * | 2020-04-09 | 2020-07-17 | 丽鑫生技化妆品（上海）有限公司 | Cool air cushion foundation and preparation method thereof |
| CN113712873A (en) * | 2021-09-26 | 2021-11-30 | 湖北省麦诗特生物科技有限公司 | Essence emulsion composition with acne-removing and anti-inflammatory effects and preparation method thereof |
| CN114767603A (en) * | 2022-03-11 | 2022-07-22 | 彭氏(惠州)实业发展有限公司 | Acne-removing cosmetic composition containing red ginseng extract |
Non-Patent Citations (2)
| Title |
|---|
| "Constituents from the Roots of Taraxacum platycarpum and Their Effect on Proliferation of Human Skin Fibroblasts";Tsutomu Warashina等;《Chem. Pharm. Bull.》;20120229;第60卷(第2期);第205-212页 * |
| "丹参挥发油与蒲公英提取物复配物在化妆品中的应用";吴颖 等;《精细化工》;20220331;第39卷(第03期);第562-568页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN115364002A (en) | 2022-11-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP3902336B2 (en) | Antibacterial plant extract and antibacterial skin external preparation containing the same | |
| CN110200884B (en) | Composition with oil control and repair effects, preparation method thereof and application thereof in cosmetics | |
| CN102342993B (en) | Anti-sensitization and restoration external preparation for skin | |
| CN111214429A (en) | Repair essence and preparation method thereof | |
| CN105078829A (en) | Chinese medicinal acne-removing face cream and preparation method thereof | |
| KR20170126142A (en) | Composition for Prevention or Improving of Atopic Dermatitis Comprising Herbal Fermentation Product with microorganism | |
| JPH08325156A (en) | Skin preparation for external use, drink and food product containing steviol glycoside | |
| KR20130015339A (en) | Cream composition for treating acne | |
| KR20080026800A (en) | Cosmetic composition | |
| KR101397160B1 (en) | Cosmetic compositon for skin-irritation alleviation with Inula britannica var. chinensis, Cynanchi Radix and Lysimachia foenum-graecum Hance | |
| CN115364002B (en) | Foundation liquid with acne removing effect and preparation method thereof | |
| CN112915055A (en) | Multi-effect mite-killing-relieving composition and application thereof | |
| KR101292274B1 (en) | Cosmetic composition for anti-wrinkle | |
| KR101969757B1 (en) | Composition comprising fermented extracts for acne treatment | |
| KR101914969B1 (en) | Hair cosmetic composition containing extract of fermented oriental medicinal herbs | |
| CN114469829A (en) | Composition for improving skin acne and inflammation and application thereof | |
| KR101427462B1 (en) | Composite Natural Antiseptics From Forsythia suspensa Vahl, Leonurus sibiricus L., Crataegi fructus and Akebia quinata Decaisne, Cosmetic Compositions Containing Them | |
| KR102146522B1 (en) | Composition of natural preservatives for cosmetic and cosmetic composition comprising the same | |
| CN113499271A (en) | Anti-allergy compound and preparation method and application thereof | |
| KR20210048021A (en) | Antibacterial compositions comprising the citrus aurantium sinensis peel extract, the magnolia officinalis bark extract and polylysine | |
| KR20110055351A (en) | Manufacturing method of fermented medicinal herb and cosmetic composition comprising the medicinal herb | |
| CN113995701B (en) | Composition for removing acnes and acne marks as well as preparation method and application thereof | |
| JPH07278001A (en) | External preparation for skin and bathing agent | |
| KR102066821B1 (en) | Natural Complex Cosmetic Preservative Composition | |
| CN107260584A (en) | Natural plants Nano Silver system snake gall acne eliminating cream |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |