CN113712873A

CN113712873A - Essence emulsion composition with acne-removing and anti-inflammatory effects and preparation method thereof

Info

Publication number: CN113712873A
Application number: CN202111127659.XA
Authority: CN
Inventors: 李沫; 杨帆; 周紫燕; 郭苗; 周正; 郭阳
Original assignee: Hubei Maishite Biotechnology Co Ltd
Current assignee: Hubei Maishite Biotechnology Co Ltd
Priority date: 2021-09-26
Filing date: 2021-09-26
Publication date: 2021-11-30
Anticipated expiration: 2041-09-26
Also published as: CN113712873B

Abstract

The invention discloses an essence emulsion composition with acne-removing and anti-inflammatory effects and a preparation method thereof. The essence milk composition comprises the following raw material components: 1-30% of acne-removing anti-inflammatory functional component, 0.5-35% of emollient, 0.5-15% of emulsifier, 1-30% of filler, 1-15% of thickener, 0.5-12% of preservative, 0.01-5% of pH regulator, 0.005-5% of daily essence and the balance of deionized water. The components with acne-removing and anti-inflammatory effects comprise: white willow bark extract, marrubium vulgare extract, palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, and fucus rudis extract. The cosmetic composition with the acne-removing and anti-inflammatory effects can achieve the effects of regulating skin grease, cleaning pores, improving acnes, repairing pores, resisting inflammation and soothing allergy by compounding the components. In addition, the four components with the acne-removing and anti-inflammatory effects have the effects of synergistically removing acne and anti-inflammatory, improving skin conditions and repairing sensitive muscles when used simultaneously, and are suitable for most of people suffering from acnes.

Description

Essence emulsion composition with acne-removing and anti-inflammatory effects and preparation method thereof

Technical Field

The invention relates to a skin care product and a preparation method and application thereof, belongs to the technical field of daily chemicals, and particularly relates to an essence emulsion composition with acne-removing and anti-inflammatory effects and a preparation method and application thereof.

Background

Acne is also called acne, is a skin problem which is concerned by people, is better to face and forehead of people, and is mainly characterized by comedo, pimple, pustule, nodule, cyst, scar and the like. What we say at ordinary times is acne vulgaris in fact. The acne not only affects the health of the skin, but also affects the beauty of the skin, and is a very headache problem, and how to effectively remove the acne needs to be understood firstly.

The occurrence of pox is closely related to factors such as hypersecretion of sebum, blockage of pilosebaceous ducts, bacterial infection, inflammatory reaction and the like. When the sebaceous gland secretes a large amount of grease, the grease blocks pores with dead skin cells, the grease cannot be accumulated in hair follicles, bacteria can be bred in the hair follicles at the moment to cause inflammation, so that redness and swelling occur, the hair follicles are cracked, and skin barriers are damaged. The main factors of people who are easy to grow acnes include more oil on skin, eating habits, irregular daily work and rest, high stress and the like, and some factors are difficult to avoid, so that how to protect skin from acnes is a problem which is more concerned by many people.

How to prepare a skin care product which can effectively prevent the generation of acnes and can resist acnes from various angles is a technical problem which needs to be solved urgently by technical personnel in the field.

Disclosure of Invention

The invention aims to provide a cosmetic composition with acne-removing and anti-inflammatory effects, which can be applied to essence milk to achieve the effects of regulating skin grease, cleaning pores, improving acnes, repairing pores, resisting inflammation and relieving allergy, and is popular among people suffering from acnes.

The invention also aims to provide a preparation method of the essence milk composition with acne-removing and anti-inflammatory effects.

The invention provides an essence emulsion composition with acne-removing and anti-inflammatory effects, which comprises the following components in percentage by total weight of the composition:

1-30% of acne-removing and anti-inflammatory functional components, which comprise: white willow bark extract, marrubium vulgare extract, palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, and fucus rudis extract;

70-99% of a cosmetic adjuvant matrix comprising: emollient, emulsifier, filler, thickener, antiseptic, pH regulator, daily essence and deionized water.

Preferably, the acne-removing anti-inflammatory efficacy component comprises the following components in percentage by weight of the total composition: 0.1-8% of white willow bark extract, 0.1-10% of marrubium vulgare extract, 0.1-8% of palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, and 0.1-6.5% of fucus rudis extract.

Preferably, the cosmetic auxiliary material matrix comprises, based on the total weight of the composition: 0.5-35% of an emollient; 0.5-15% of emulsifier; 1-30% of a filler; 1-15% of a thickening agent; 0.5-12% of a preservative; 0.01-5% of pH regulator; 0.005-5% of daily essence; the balance being deionized water.

Preferably, the essence milk composition with the acne-removing and anti-inflammatory effects comprises the following components in percentage by weight of the total composition:

1-18% of acne-removing anti-inflammatory efficacy ingredients comprising: 0.1-5% white willow bark extract, 0.5-6% marrubium vulgare extract, 0.1-3% palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, and 0.1-4.5% Fucus serratus extract;

82-99% of a cosmetic adjunct base comprising: 5-30% of an emollient; 1-15% of an emulsifier; 1-25% of a filler; 1-12% of a thickening agent; 0.5-5% of preservative; 0.01-4% of pH regulator; 0.015-4% of daily essence; the balance being deionized water.

Preferably, the essence milk composition with acne-removing and anti-inflammatory effects comprises the following components in percentage by weight of the total composition:

acne-removing anti-inflammatory efficacy ingredients comprising: 0.5-1% of white willow bark extract, 0.5-1.5% of marrubium vulgare extract, 0.1-0.5% of palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, and 0.5-1% of fucus rudis extract;

a cosmetic adjuvant matrix comprising: 5-15% of an emollient; 1-5% of an emulsifier; 1-5% of a filler; 5-12% of a thickening agent; 1-2% of a preservative; 0.2-2% of pH regulator; 0.04-1% of daily essence; the balance being deionized water.

Preferably, the weight ratio of the white willow bark extract, the marrubium vulgare extract, the palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7 and the fucus rudis extract in the acne-removing and anti-inflammatory efficacy components is 1: (1-1.5): (0.12-0.45): (0.65-1.25); wherein the mass ratio of the palmitoyl tripeptide-1 to the palmitoyl tetrapeptide-7 is 1: (0.5 to 1.4).

Preferably, the preparation method of the white willow bark extract comprises the following steps:

1) cleaning raw materials, drying, pulverizing, and sieving to obtain raw material powder;

2) charging raw material powder into supercritical extraction kettle, and adding CO₂The entrainer is added into the supercritical CO in a small amount in a liquid form₂Fully contacting with the raw material powder to selectively dissolve out the required chemical components;

3) CO containing dissolved extract₂The fluid is depressurized by a pressure reducing valve and enters a separation kettle, and solute is dissolvedThe solubility is greatly reduced to precipitate solute, and the solute is concentrated under reduced pressure to dryness to obtain extract.

Preferably, the preparation method of the white willow bark extract is characterized in that the extraction temperature is 35-60 ℃; the extraction pressure is 20-60 Mpa; the extraction time is 1-4 h; the entrainer is one or more of water, methanol, ethanol, acetone and propane.

Preferably, the marrubium vulgare extract and the fucus serratus extract are both obtained by supercritical carbon dioxide fluid extraction.

Preferably, the emollient is selected from one or more of butylene glycol, hexylene glycol, pentylene glycol, behenyl alcohol, caprylic/capric triglyceride, squalane, avocado oil, shea butter, jojoba oil, olive oil, dimethiconol, isohexadecane, phytosterols, polydecene, isononyl isononanoate;

preferably, the emulsifier is selected from one or more of polysorbate-20, laureth-23, sorbitan olivate, steareth-21, polysorbate-80, soybean lecithin PC60, glycerol stearate;

preferably, the filler is selected from one or more of boron nitride, synthetic fluorophlogopite, diatomaceous earth, kaolin, cellulose acetate, aluminum starch octylsuccinate;

preferably, the thickener is selected from one or more of glycerin, 1, 3-propylene glycol, carbomer, xanthan gum, acrylic acid/C10-30 alkanol acrylate crosspolymer, gum arabic, polymer EMT-10, sodium acrylate/sodium acryloyldimethyl taurate, acrylic acid/C10-30 alkanol acrylate crosspolymer copolymer;

preferably, the preservative is selected from one or more of phenoxyethanol, ethylhexyl glycerol, jasmone, sodium benzoate, pentanediol and hexanediol;

preferably, the pH adjusting agent is selected from one or more of lactic acid or arginine.

Preferably, the preparation method of the essence milk composition with acne removing and anti-inflammatory effects comprises the following steps:

1) wetting and completely dispersing the thickening agent in water to obtain a mixed solution;

2) adding acne-removing and anti-inflammatory functional components, an emollient, a filler, a preservative and a pH regulator into the mixed solution obtained in the step 1), heating to 65 ℃, and homogenizing at 3000r/min for 3 minutes to completely disperse the mixture;

3) adding an emulsifier and a daily essence into the step 2), homogenizing at 3000r/min for 3 minutes to completely emulsify, and heating to 65 ℃ to obtain the essence emulsion composition with the acne removing and anti-inflammatory effects.

Specifically, the essence milk composition with acne-removing and anti-inflammatory effects has a pH value within a range of 4-10, preferably a pH value within a range of 5-8, and most preferably a pH value within a range of 5-7.

Specifically, the essence emulsion composition with the acne removing and anti-inflammatory effects is not limited to essence emulsion formulations, and can also be used in other cosmetic formulations.

The invention provides a cosmetic which comprises the essence milk composition with the acne-removing and anti-inflammatory effects, which is prepared by the preparation method.

Preferably, the cosmetic is in the form of a solvent dispersion or suspension, or in the form of emulsified particles, or in the form of a polymer coating.

By means of the technical scheme, the invention has the following beneficial technical effects:

1) the acne-removing and anti-inflammatory efficacy components comprise white willow bark extract, marrubium vulgare extract, palmitoyl tripeptide-1, palmitoyl tetrapeptide-7 and fucus rudis extract, have the effects of regulating skin grease, cleaning pores, improving acnes, repairing pores, resisting inflammation and soothing allergy, and are wide in applicable population;

2) in addition, when the acne-removing and anti-inflammatory efficacy components are compounded for use, acne resistance can be realized from all aspects, namely acne elimination, acne damage caused by acne repair and acne prevention, and the skin acne crisis can be solved in multiple directions and multiple angles;

3) the innovative acne-removing and anti-inflammatory functional ingredients are simultaneously applied to the essence milk, and can also play a role in synergy of acne-removing and anti-inflammatory.

Drawings

Fig. 1 is an antibacterial experiment result diagram of acne-removing and anti-inflammatory efficacy components;

FIG. 2 is the rate of change of volume of skin acne after use of the sample;

FIG. 3 is the rate of change of skin inflammatory acne grade after use of the sample;

FIG. 4 shows the effectiveness of skin acne reduction after use of the sample;

fig. 5 is a graph of the rate of change of skin acne volume after the use of example 1 and control examples 1-14.

Detailed Description

The invention discloses an essence emulsion composition with acne-removing and anti-inflammatory effects and a preparation method thereof. The essential milk composition mainly comprises the following components in percentage by weight: white willow bark extract, marrubium vulgare extract, palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, and fucus rudis extract. It has effects in regulating skin oil and fat, cleaning follicular orifice, improving acne, repairing follicular orifice, resisting inflammation, and relieving allergy. In addition, the four components with the acne removing and anti-inflammatory effects can be used simultaneously, and can also achieve the synergistic acne removing and anti-inflammatory effects.

Wherein the white willow bark extract mainly plays a role in eliminating pox in the serum. The effective component of the white willow bark extract is salicin which is called natural salicylic acid, has the effects of conditioning cutin, reducing skin secretion grease, resisting bacteria and diminishing inflammation, can effectively reduce sebum blockage at pockmarks and bacterial breeding, and also has the effects of reducing inflammation and relieving the skin.

The two active polypeptides of palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7 have the main functions of regulating cell activity and promoting skin repair process. The skin care essence mainly plays a role in repairing skin barrier damage caused by the occurrence of the acne in the essence milk, can also enhance the repairing function of the skin, and can effectively improve the acne muscle and the sensitive muscle. The mass ratio of the palmitoyl tripeptide-1 to the palmitoyl tetrapeptide-7 is 1: (0.5 to 1.4).

The extract of the marrubium vulgare has the main function of preventing the occurrence of the acne, the prevention of the acne is mainly to keep pores unobstructed, and the extract of the marrubium vulgare can strengthen the skin barrier and prevent the skin from being invaded by pollutants; it can prevent dirt accumulation caused by pollution, block pores, and further prevent skin sensitivity from developing into pox.

The fucus extract contains various essential amino acids of a human body, provides various nutrients for skin, seriously influences the metabolism level of skin cells when the skin lacks nutrients and is influenced by external factors such as air pollution, smoking, diet, pressure, aging and the like, so that the skin is aged and has insufficient activity, old cells can block pores, and the source of pox is formed. The Fucus serratus extract can permeate and nourish, awaken the skin, activate cells, promote metabolism and ensure that the skin breathes more smoothly.

The invention innovatively combines the four acne-removing and anti-inflammatory functional components, can resist acne from all aspects, can eliminate the acne, can repair skin damage caused by the acne, can prevent the acne, and can solve the skin acne crisis from multiple directions and angles.

The present invention is illustrated by the following examples, which are provided for the purpose of further illustration only and are not intended to limit the scope of the present invention. Other insubstantial modifications and adaptations of the present invention can be made without departing from the scope of the present invention. Unless otherwise specified, the following percentages (%) are mass percentages.

Examples 1 to 3

A cosmetic composition with acne removing and anti-inflammatory effects is prepared into essence milk, and the content of the raw material components is shown in the following table 1.

TABLE 1 raw material component ratios (% by mass) of examples 1 to 3

The preparation process of the essence milk with acne removing and anti-inflammatory effects in the embodiment 1 comprises the following steps:

1) respectively mixing 12g of white willow bark and 12g of Europe summer solsticeGrass, 15g Fucus serratus after washing were prepared: drying, crushing, and sieving with a 50-mesh sieve to obtain raw material powder for later use; charging raw material powder into supercritical extraction kettle in several times, and adding CO₂The mixture enters from the bottom of the extraction kettle after pressure and temperature regulation, and a small amount of 65 percent ethanol serving as an entrainer is added into supercritical CO₂Fully contacting with the raw material powder to selectively dissolve the required chemical components, wherein the extraction temperature is 35 ℃, and the extraction pressure is 40 Mpa; the extraction time is 1.5 h; CO containing dissolved extract₂The fluid is depressurized by a pressure reducing valve, enters a separation kettle, the solubility of the solute is greatly reduced, so that the solute is separated out, and the extract can be obtained by concentrating the solute under reduced pressure until the solute is dried.

2) Wetting and completely dispersing the thickening agent in water to obtain a mixed solution;

3) adding 0.5 part of white willow bark extract, 0.5 part of marrubium vulgare extract, 0.2 part of palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, and 0.6 part of fucus rudis extract into the mixed solution in the step 2);

4) adding an emollient, a filler, a preservative and a pH regulator into the mixed solution obtained in the step 3), heating to 65 ℃, and homogenizing at 3000r/min for 3 minutes to completely disperse the mixed solution;

5) adding an emulsifier and a daily essence into the step 4), homogenizing at 3000r/min for 3 minutes to completely emulsify the mixture, and heating to 65 ℃ to obtain the cosmetic composition with the acne removing and anti-inflammatory effects.

The preparation process of the essence milk with acne removing and anti-inflammatory effects in the embodiment 2 comprises the following steps:

1) respectively cleaning 20g of white willow bark, 20g of marrubium vulgare and 25g of fucus rudis, and then preparing: drying, crushing, and sieving with a 60-mesh sieve to obtain raw material powder for later use; charging raw material powder into supercritical extraction kettle in several times, and adding CO₂The mixture enters from the bottom of the extraction kettle after pressure and temperature regulation, and the entrainer is 75 percent ethanol which is added into the supercritical CO in small amount₂Fully contacting with the raw material powder to selectively dissolve the required chemical components, wherein the extraction temperature is 40 ℃, and the extraction pressure is 25 Mpa; the extraction time is 2 hours; CO containing dissolved extract₂The fluid is depressurized by a pressure reducing valve and enters a separation kettle, so that the solubility of solute is greatly reducedPrecipitating solute, and concentrating the solute under reduced pressure to dryness to obtain extract.

3) adding 1 part of white willow bark extract, 1.2 parts of marrubium vulgare extract, 0.4 part of palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, and 0.7 part of fucus rudis extract into the mixed solution in the step 2);

The preparation process of the essence milk with acne removing and anti-inflammatory effects in the embodiment 3 comprises the following steps:

1) the preparation method comprises the following steps of respectively cleaning 42g of white willow bark, 42g of marrubium vulgare and 55g of fucus rudis, and then preparing: drying, crushing, and sieving with a 80-mesh sieve to obtain raw material powder for later use; charging raw material powder into supercritical extraction kettle in several times, and adding CO₂The mixture enters from the bottom of the extraction kettle after pressure and temperature regulation, and the entrainer is 75 percent ethanol which is added into the supercritical CO in small amount₂Fully contacting with the raw material powder to selectively dissolve the required chemical components, wherein the extraction temperature is 36 ℃, and the extraction pressure is 40 Mpa; the extraction time is 3 h; CO containing dissolved extract₂The fluid is depressurized by a pressure reducing valve, enters a separation kettle, the solubility of the solute is greatly reduced, so that the solute is separated out, and the extract can be obtained by concentrating the solute under reduced pressure until the solute is dried.

3) adding 1 part of white willow bark extract, 1.5 parts of marrubium vulgare extract, 0.3 part of palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, and 0.8 part of fucus rudis extract into the mixed solution in the step 2);

Test example for Effect verification

1. Safety test

Test samples: example 1;

the test method comprises the following steps: and (4) testing the safety by adopting a third-party detection mechanism. The selection area is not more than 50mm²And a suitable patch device having a depth of about 1mm, wherein about 0.02 to about 0.025ml (g) of the test substance is applied to the patch device in a closed patch test. The patch tester is attached to the curved side of the forearm of the subject, the subject is removed 24h later, the skin reaction is observed 0.5h, 24h and 48h after the removal, and the result is recorded according to the skin reaction grading standard in the technical regulation for cosmetic safety 2015.

TABLE 2 Patch test results

Remarking: grading standard of skin reaction;

level 0: negative reaction;

level 1: carrying out suspicious reaction; only faint erythema;

and 2, stage: weak positive reaction (erythema reaction); erythema, infiltration, edema, and possibly papules;

and 3, level: strong positive reaction (herpes reaction); erythema, infiltration, edema, pimples, herpes; the reaction may be beyond the test area;

4, level: very strong response (fusional herpes response); erythema, severe infiltration, edema, fusional herpes, and response beyond the test area.

As can be seen from table 2 above, the prepared essence milk showed no irritation and passed safety.

2. Stability test

Test samples: example 1;

the test method comprises the following steps: and (5) observing the appearance color, viscosity and pH value for three months according to internal control standard.

Table 3 stability test results

Time

45℃

40℃

37℃

25℃

5℃

-15℃

CYCLE

Illumination of light

1W

√

2W

√

3W

√

4W

√

2M

√

3M

√

From the above table 3, the prepared essence milk has no significant changes in color, viscosity and pH value within three months under high and low temperature or illumination conditions, which indicates that the essence milk has better stability.

3. Antibacterial experiment effect test of acne-removing and anti-inflammatory components

Test samples: the anti-acne anti-inflammatory efficacy ingredients in example 1 (0.5% white willow bark extract, 0.5% marrubium vulgare extract, 0.2% palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, 0.6% fucus rudis extract).

The test method comprises the following steps: the salicylic acid content with the same activity is adopted for comparison, and the antibacterial ability of the acne-removing and anti-inflammatory component is measured by a bacteriostatic ring method.

And (3) testing results: the largest diameter of the bacteriostatic ring of the acne-removing and anti-inflammatory composition can be seen from fig. 1, and the acne-removing and anti-inflammatory composition has the same efficacy of resisting propionibacterium acnes as salicylic acid with the same activity, which indicates that the acne-removing and anti-inflammatory composition has ideal efficacy of inhibiting bacterial growth and preventing pore blockage from generating inflammation to generate acne.

4. Evaluation of efficacy of essence milk with acne-removing and anti-inflammatory effects

Test samples: example 1;

the test method comprises the following steps: twice a day, in the morning and at night. The appropriate amount of test sample was applied to the entire face, using the sunscreen product to apply to the entire face every morning.

The results were tested at the following 4 time periods, respectively: before use of the sample (D0), after use of the sample for 14 days (D14), after use of the sample for 28 days (D28) and after use of the sample for 56 days (D56).

The detection items are as follows:

primos for facial image acquisition and acne analysis

Clinical evaluation of subjects by dermatologists

And (3) testing results:

as shown in fig. 2 and table 4, which are the results of the clinical efficacy testing experiment of example 1, the volume value of acne was significantly reduced by 34.13%, 43.45%, 45.76% after 14 days of use (D14), 28 days of use (D28) and 56 days of use (D56).

TABLE 4 volume change rate of skin acne

Time	After 14 days of use (D14)	After 28 days of use (D28)	After 56 days of use (D56)
				Rate of change	-34.13％	-43.45％	-45.76％

As shown in fig. 3-4, tables 5-6, which are the results of clinical evaluation by the dermatologist of example 1, the inflammatory acne grade was significantly reduced by 22.22%, 15.87%, 30.16% after 14 days of use (D14), 28 days of use (D28), 56 days of use (D56); the effective rate of facial acne is 13%, 30% and 77%.

TABLE 5 inflammatory acne grade Change Rate

TABLE 6 effective rate of acne decline

Time	After 14 days of use (D14)	After 28 days of use (D28)	After 56 days of use (D56)
				High efficiency	13％	30％	77％

In conclusion, the prepared essence milk composition with the acne removing effect can effectively improve the facial acne problem.

5. Synergistic experiment of acne-removing and anti-inflammatory composition

A cosmetic composition with acne removing and anti-inflammatory effects is prepared into essence milk, and the contents of the raw material components in the essence milk in the comparison examples 1-14 are shown in the following tables 7-8.

TABLE 7 ingredient ratio table (unit: mass%) of anti-acne and anti-inflammatory essence milks of comparative examples 1 to 7

TABLE 8 ingredient ratio table (unit: mass%) of anti-acne and anti-inflammatory essence milks of control examples 8 to 14

The preparation process of the essence milk with acne removing and anti-inflammatory effects comprises the following steps:

3) adding an emulsifier and a daily essence into the step 2), homogenizing at 3000r/min for 3 minutes to completely emulsify the mixture, and heating to 65 ℃ to obtain the cosmetic composition with the acne removing and anti-inflammatory effects.

The effects of the examples of the synergistic experiment of the acne-removing and anti-inflammatory components and the comparative examples 1 to 14 are verified, and the experimental steps and results are as follows:

1) the tester: 150 healthy women (20-45 years old) divided into 15 groups of 10 persons each; each group used the same formulation.

2) Test area: the entire face.

3) Use of: twice a day, in the morning and at night. The appropriate amount of test sample was applied to the entire face, using the sunscreen product to apply to the entire face every morning.

The results were tested at the following 4 time periods, respectively: before use of the sample (D0), after use of the sample for 14 days (D14), after use of the sample for 28 days (D28), after use of the sample for 56 days (D56)

4) Testing an instrument: primos

5) The effect indexes are as follows: primos was used for facial image acquisition and acne analysis.

6) The test results are shown in table 8.

TABLE 9 test group Effect

From table 9, the results in fig. 5 show that when white willow bark extract, marrubium vulgare extract, palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7 and fucus serrata extract are simultaneously added into the essence milk, the acne reduction capability is 34.13%, 43.45% and 45.76% respectively on days 14, 28 and 56, and the acne resistance capability is significantly higher than that of the comparative examples 1-14, which indicates that, under the same total proportion, the acne resistance capability of four components simultaneously used is significantly improved compared with that of a certain component and a single component, and the synergistic function of the four components in the aspect of acne removal can be obtained. The synergistic function is realized because the four components adopted by the Chinese medicinal composition have different division and cooperation in the aspects of acne removal and inflammation resistance, and can solve the problems of skin acne from eliminating the acne to repairing skin damage caused by the acne to preventing the acne from occurring in multiple directions and multiple angles.

The above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention in any way, so that any simple modification, equivalent change and modification made to the above embodiment according to the technical spirit of the present invention are within the scope of the technical solution of the present invention.

Claims

1. The essence emulsion composition with the acne-removing and anti-inflammatory effects is characterized by comprising the following components in percentage by weight of the total composition:

2. The essence milk composition with acne-removing and anti-inflammatory effects according to claim 1, wherein the acne-removing and anti-inflammatory effects comprise the following components in percentage by weight of the total composition: 0.1-8% of white willow bark extract, 0.1-10% of marrubium vulgare extract, 0.1-8% of palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, and 0.1-6.5% of fucus rudis extract.

3. The essence cream composition with acne-removing and anti-inflammatory effects of claim 1, wherein the cosmetic auxiliary material matrix comprises, based on the total weight of the composition: 0.5-35% of an emollient; 0.5-15% of emulsifier; 1-30% of a filler; 1-15% of a thickening agent; 0.5-12% of a preservative; 0.01-5% of pH regulator; 0.005-5% of daily essence; the balance being deionized water.

4. The essential milk composition with acne-removing and anti-inflammatory effects as claimed in claim 1, which is composed of the following components by weight:

5. The essence milk composition with the acne-removing and anti-inflammatory effects as claimed in any one of claims 1 to 4, wherein the weight ratio of white willow bark extract, marrubium vulgare extract, palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, and fucus rudis extract in the ingredients with the acne-removing and anti-inflammatory effects is 1: (1-1.5): (0.12-0.45): (0.65-1.25); wherein the mass ratio of the palmitoyl tripeptide-1 to the palmitoyl tetrapeptide-7 is 1: (0.5 to 1.4).

6. The essence cream composition with acne-removing and anti-inflammatory effects as claimed in any one of claims 1 to 5, wherein the white willow bark extract, the marrubium vulgare extract and the fucus rudis extract are obtained by supercritical carbon dioxide fluid extraction, and the preparation method comprises the following steps:

3) CO containing dissolved extract₂The fluid is depressurized by a pressure reducing valve, enters a separation kettle, the solubility of the solute is greatly reduced, so that the solute is separated out, and the extract can be obtained by concentrating the solute under reduced pressure until the solute is dried.

7. The essence cream composition with acne-removing and anti-inflammatory effects of claim 6, wherein in the preparation method of the supercritical carbon dioxide fluid extraction, the extraction temperature is 35-60 ℃; the extraction pressure is 20-60 Mpa; the extraction time is 1-4 h; the entrainer is one or more of water, methanol, ethanol, acetone and propane.

8. The essence milk composition with acne-removing and anti-inflammatory effects as claimed in any one of claims 1 to 6, wherein:

the emollient is selected from one or more of butanediol, hexanediol, pentanediol, behenyl alcohol, caprylic glycol, caprylic capric triglyceride, squalane, avocado oil, shea butter, jojoba oil, olive oil, dimethiconol, isohexadecane, phytosterol, polydecene, isononyl isononanoate;

the emulsifier is one or more selected from polysorbate-20, laureth-23, sorbitan olive oleate, steareth-21, polysorbate-80, soybean lecithin PC60, and glycerol stearate;

the filler is selected from one or more of boron nitride, synthetic fluorophlogopite, diatomite, kaolin, cellulose acetate and aluminum starch octylsuccinate;

the thickening agent is selected from one or more of glycerin, 1, 3-propylene glycol, carbomer, xanthan gum, acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, gum arabic, polymer EMT-10, sodium acrylate/sodium acryloyldimethyl taurate, acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer copolymer;

the preservative is selected from one or more of phenoxyethanol, ethylhexyl glycerol, jasmone, sodium benzoate, pentanediol and hexanediol;

the pH regulator is selected from one or more of lactic acid or arginine.

9. The preparation method of the essence milk composition with the acne-removing and anti-inflammatory effects as claimed in any one of claims 1-8, is characterized by comprising the following steps:

10. A cosmetic characterized by: the cosmetic comprises the essence milk composition with acne removing and anti-inflammatory effects prepared by the preparation method of claim 9.