CN112915055A

CN112915055A - Multi-effect mite-killing-relieving composition and application thereof

Info

Publication number: CN112915055A
Application number: CN202110251433.4A
Authority: CN
Inventors: 陈汉伦; 马志冰; 陆海勇
Original assignee: Hangzhou Shanduishan Trading Co ltd; Guangzhou Zhishang Biology Biology Co ltd
Current assignee: Hangzhou Shanduishan Trading Co ltd; Guangzhou Zhishang Biology Biology Co ltd
Priority date: 2021-03-08
Filing date: 2021-03-08
Publication date: 2021-06-08

Abstract

The invention discloses a multi-effect miticidal composition capable of relieving, which comprises a pelargonium roseum extract, a fructus forsythiae extract, a mint leaf extract, a sophora flavescens root extract and a rosemary extract, and is applied to daily necessities. The composition provided by the invention can sterilize, inhibit bacteria, kill and inhibit mites, balance grease secretion, remove factors which continuously damage skin such as inflammation, free radicals and the like, repair the skin, radically solve the problem of skin damage, improve the skin state and enable the skin to return to a healthy state.

Description

Multi-effect mite-killing-relieving composition and application thereof

Technical Field

The invention belongs to the technical field of daily necessities, and particularly relates to a multi-effect mite-killing-relieving composition and application thereof.

Background

With the increase of daily activities, the chance that human skin contacts mites is increased, and parasitic mites are increased to easily cause various skin diseases. The mites parasitizing on human bodies are mainly divided into two types, one is hair follicle mite, also called demodex hominis, and the other is sebaceous gland mite, parasitizing on the sebaceous gland of the human face, and the mites are commonly called mites for short. Mites mostly parasitize the pilosebaceous glands and take up intracellular nutrients and sebaceous gland secretions, thereby causing the breakage of normal cells. Due to the mechanical stimulation of the polypide and the chemical stimulation of the polypide excreta, the parasitic part can cause the symptoms of hair follicle enlargement, blood vessel expansion, peripheral cell infiltration, fibrous tissue hyperplasia and the like. The breeding of facial mites often causes skin damage, such as folliculitis, seborrheic dermatitis, blepharitis, acne, rosacea and the like, thereby stimulating the market demand of mite-killing products.

The existing mite killing products on the market are various in quality and mainly contain chemical medicines, and although the mite killing products have certain effects on killing mites, the mite killing products have the problems that skin surfaces are easy to remain and the like, and the skin health is influenced. And most of mite inhibiting products have single mite inhibiting way, and the mites are inhibited by removing redundant grease to prevent mites and bacteria from breeding in a large quantity. However, deep research on the action mechanism of the skin disease caused by mites shows that the aims of preventing and treating the mites by inhibiting grease secretion are far from being sufficient. The botanical drug is not easy to generate drug resistance, can be degraded automatically in the environment, is mild and safe, and is concerned. Therefore, there is a market trend to develop mild, safe and efficient mite-killing products of plant origin.

Disclosure of Invention

Aiming at the technical problems, the invention provides a multi-effect miticidal composition capable of relieving and application thereof, which can kill bacteria, inhibit bacteria, kill and inhibit mites, balance grease secretion, remove factors which continuously damage skin such as inflammation and free radicals and repair skin, radically solve the problem of skin damage, improve the skin state and enable the skin to return to a healthy state.

Therefore, the first technical scheme provided by the application is as follows:

a composition for soothing multiple-effect mite killing comprises Pelargonium graveolens extract, fructus forsythiae extract, folium Menthae extract, radix Sophorae Flavescentis extract and herba Rosmarini officinalis extract.

The efficacy of the components of the composition of the invention is as follows:

geranium extract: the geraniol essential oil contains geraniol, linalool, citronellol and the like, and researches show that the geraniol essential oil has broad-spectrum sterilization and bacteriostasis effects on pathogenic bacteria and nonpathogenic bacteria. Can balance skin secretion, is beneficial to eczema, burn, herpes zoster and chilblain, and can lighten acne marks and prevent blackheads and pimples, and the pale and non-viable skin is ruddy and active after the geranium is used.

Menthol in the mint leaf extract can reduce the activity of intracellular Ca-ATP enzyme, so that intracellular Ca can not be pumped out of cells, the concentration of the intracellular Ca is indirectly increased, actin filaments are contracted, the cell gap is increased, and the skin permeability is increased. The extract is rich in active ingredients such as flavone and saponin, has good antioxidant activity while playing the anti-inflammatory and analgesic functions, and has good protection effect on other active ingredients.

The forsythia suspense extract has certain hydroxyl free radical scavenging capacity, certain DPPH free radical scavenging capacity and certain reducing capacity, the free radical scavenging capacity and the reducing capacity are gradually enhanced along with the increase of the concentration of the polysaccharide, and the forsythia suspense extract can be applied to natural green nutritional preparations. Fructus forsythiae has effects of clearing away heat and toxic materials, and resisting bacteria and inflammation, and can be used for treating skin diseases such as acne, rubella, and verruca plana.

The rosemary extract can be divided into oil-soluble and water-soluble extracts, wherein the former is mainly carnosic acid, and the latter is mainly rosmanol. The rosemary extract is natural and non-toxic, the antioxidant effect of the rosemary extract is far higher than that of the existing natural antioxidants such as vitamin C, vitamin E, tea polyphenol and the like, the antioxidant effect of the rosemary extract is 2-4 times that of the artificially synthesized antioxidants BHA and BHT, the rosemary extract is stable in structure and not easy to decompose, the rosemary extract can resist the high temperature of 190 ℃ to 240 ℃, the consistent weakness that most of the natural antioxidants such as the vitamin C and the tea polyphenol are decomposed when meeting high temperature is thoroughly overcome, and compared with other similar products, the rosemary extract has the advantages of higher efficiency and broad spectrum. The antioxidant function of rosemary mainly lies in that rosemary can quench singlet oxygen, clear free radicals, chelate metal ions, synergize organic acid and the like. The rosemary is scientifically proved to be the most safe and efficient natural antioxidant which is generally accepted in the world at present.

The preferable technical scheme comprises 1-8 parts of pelargonium graveolens extract, 1-5 parts of fructus forsythiae extract, 1-5 parts of mint leaf extract, 0.5-3 parts of sophora flavescens root extract and 2-6 parts of rosemary extract by weight.

The preferable technical scheme comprises, by weight, 2-7 parts of pelargonium graveolens extract, 2-4 parts of fructus forsythiae extract, 2-4 parts of mint leaf extract, 1-3 parts of sophora flavescens root extract and 3-5 parts of rosemary extract.

The preferable technical proposal also comprises a sage extract.

The sage extract is prepared from sage and has the effects of relieving, conditioning skin, resisting oxidation and the like. The Salvia officinalis volatile oil has strong fresh fragrance, can be used for preparing food and cosmetic essence, can also be used as fumigant and medicine, and has dual functions of tranquilizing and relieving. Can obviously inhibit infection caused by gram-positive bacteria and gram-negative bacteria, and is used for preventing and treating gingivitis, stomatitis and the like of oral hygiene products. The compound has an activating effect on luciferase, which shows that the compound has anti-inflammation; has effect in inhibiting phosphodiesterase, reducing oil and fat production, promoting hydrolysis of oil and fat in fat hydrolysis test, and can be used as cosmetic additive for tightening skin and reducing weight by combining with contraction effect on collagen cellulite.

In a preferable technical scheme, the adding amount ratio of the sage extract to the mint leaf extract is 1-3: 1-3.

The second technical scheme provided by the application is as follows:

the multi-effect mite-killing soothing composition is applied to preparation of daily necessities, wherein the daily necessities comprise any one of soaps, water aqua, emulsions, creams, gels, facial mask daily necessities or washing and protecting daily necessities.

According to the preferable technical scheme, the addition amount of the multi-effect mite-killing-relieving composition in the daily necessities is 0.01-25%.

According to the preferable technical scheme, the addition amount of the multi-effect mite-killing-relieving composition in the daily necessities is 0.1-15%.

Compared with the prior art, the invention has the following beneficial effects:

the composition of various plant extracts is provided by scientific and reasonable compounding, and comprises a mint leaf extract, a pelargonium graveolens extract, a forsythia suspense extract, a sophora flavescens root extract, a rosemary extract and the like, and all components in the composition perform synergistic action to play a role, so that the composition can be used for removing bacteria and mites, inhibiting inflammation, clearing factors damaging the skin, repairing skin cells and enhancing the skin activity, and further can be used for removing mites and repairing and improving the skin from the root; the composition provided by the invention is pure natural in components, free of irritation, safe, free of toxic and side effects and remarkable in effect.

Detailed Description

The following claims are hereby incorporated into the detailed description of the invention, with the understanding that the invention is not to be limited in any way, as any number of modifications may be made by one within the scope of the claims and the invention is still within the scope of the claims.

The raw materials used in the multi-effect mite-killing composition for relieving provided by the invention are all available in the market.

Example 1

The invention provides a multi-effect mite-killing-relieving composition which comprises the following components in parts by weight: 2g of pelargonium graveolens extract, 3g of fructus forsythiae extract, 4g of mint leaf extract, 1g of sophora flavescens root extract and 4g of rosemary extract.

Example 2

The invention provides a multi-effect mite-killing-relieving composition which comprises the following components in parts by weight: 8g of pelargonium graveolens extract, 1g of fructus forsythiae extract, 2g of mint leaf extract, 2g of sophora flavescens root extract and 2g of rosemary extract.

Example 3

The invention provides a multi-effect mite-killing-relieving composition which comprises the following components in parts by weight: 4g of pelargonium graveolens extract, 4g of fructus forsythiae extract, 3g of mint leaf extract, 1g of sophora flavescens root extract and 3g of rosemary extract.

Example 4

The invention provides a multi-effect mite-killing-relieving composition which comprises the following components in parts by weight: 5g of pelargonium graveolens extract, 2g of fructus forsythiae extract, 3g of mint leaf extract, 1g of sophora flavescens root extract and 3g of rosemary extract.

Example 5

The invention provides a multi-effect mite-killing-relieving composition which comprises the following components in parts by weight: 3g of pelargonium graveolens extract, 2g of fructus forsythiae extract, 4g of mint leaf extract, 2g of sophora flavescens root extract, 3g of rosemary extract and 3g of sage extract.

Example 6

The invention provides a multi-effect mite-killing-relieving composition which comprises the following components in parts by weight: the traditional Chinese medicine composition comprises 6g of pelargonium graveolens extract, 3g of fructus forsythiae extract, 2g of mint leaf extract, 1g of sophora flavescens root extract, 2g of rosemary extract and 1g of sage extract.

Example 7

The invention provides a multi-effect mite-killing-relieving composition which comprises the following components in parts by weight: 4g of pelargonium graveolens extract, 3g of fructus forsythiae extract, 4g of mint leaf extract, 0.5g of sophora flavescens root extract, 2g of rosemary extract and 4g of sage extract.

Example 8

The invention provides a multi-effect mite-killing-relieving composition which comprises the following components in parts by weight: 5g of pelargonium graveolens extract, 1g of fructus forsythiae extract, 3g of mint leaf extract, 2g of sophora flavescens root extract, 4g of rosemary extract and 2g of sage extract.

Example 9

The invention provides a multi-effect mite-killing-relieving composition which comprises the following components in parts by weight: 7g of pelargonium graveolens extract, 2g of fructus forsythiae extract, 1g of mint leaf extract, 1g of sophora flavescens root extract, 5g of rosemary extract and 3g of sage extract.

Example 10

The invention provides a multi-effect mite-killing-relieving composition which comprises the following components in parts by weight: 2g of pelargonium graveolens extract, 4g of fructus forsythiae extract, 2g of mint leaf extract, 1g of sophora flavescens root extract, 3g of rosemary extract and 2g of sage extract.

To demonstrate the effect of the present invention, comparative experimental examples of the present application are given below:

comparative example 1

A composition comprising the following components in parts by weight: 3g of pelargonium graveolens extract, 1g of fructus forsythiae extract and 2g of sophora flavescens root extract.

Comparative example 2

A composition comprising the following components in parts by weight: 2g of fructus forsythiae extract, 3g of mint leaf extract and 1g of sophora flavescens root extract.

Comparative example 3

A composition comprising the following components in parts by weight: 3g of fructus forsythiae extract, 0.5g of sophora flavescens root extract, 2g of rosemary extract and 1g of sage extract.

Comparative example 4

A composition comprising the following components in parts by weight: 3g of pelargonium graveolens extract, 0.5g of sophora flavescens root extract, 2g of rosemary extract and 1g of sage extract.

In order to better illustrate the advantages of the present invention, the experimental results of the technical solutions provided by the present invention are given below.

Testing one: skin irritation test

(1) Test samples: the mite-killing compositions prepared in examples 1-10.

(2) The test method comprises the following steps: 50 healthy volunteers are selected, the age is 18-45 years, the test subjects meet the volunteer selection standard, no history of allergic dermatitis exists, and no irritant product is used in the previous month. About 0.020-0.025 ml of a test sample is taken and coated in a small chamber of a spot tester (Beijing science popularization instrument factory), a special adhesive tape for external use is applied to the back of a testee, the spot tester is removed after 24 hours, if the residual product is slightly wiped off by a wet paper towel, the results are recorded according to the skin reaction grading standard in the technical Specification for cosmetic safety (2015) at 0.5 hour, 24 hours and 48 hours respectively, and the results are shown in Table 1.

TABLE 1 identification standards

Grade	Identification criteria
		0	Has no irritation and erythema
1	Mild erythema
		2	Erythema
3	Erythema, pimples, blisters
		4	Severe edema and bulla

As can be seen from the results of the closed patch test, 50 subjects showed no adverse reaction and no erythema, burning sensation, itching, etc. at 0.5 hour, 24 hours, and 48 hours with respect to the compositions provided in examples 1 to 10. The mite-killing composition is safe and mild to use and has no stimulation to skin.

And (2) testing: testing of mite-killing and mite-killing efficacy

(1) Test samples: the compositions of examples 1 to 10 and the mite removing compositions of comparative examples 1 to 4 were each prepared as a sample solution with a mass fraction of 3.0%, and the following tests were carried out:

(2) mite removal test method: taking a glass jar, taking 3g of a test sample, adding 6L of water, and stirring until the test sample is completely dissolved; taking 20cm × 10cm cloth, folding into 10cm × 10cm double-layer cloth, wrapping 100 mites therein, placing into the above glass jar, totally immersing into liquid, opening the stirrer to middle level, and stirring for 5 min. Taking out the cloth, pouring out the water in the glass jar, adding 6L of clean water again, putting the cloth in the water in the glass jar again, stirring for 5min, and repeating the step for 3 times; and taking out the cloth, observing, recording the number of mites on the cloth, and calculating the mite washing rate. The experiment was repeated three times. Note: the mites of this experiment were dust mites that can cause allergic reactions in humans.

Calculating the formula:

the mite removing rate (%) - (I-II)/I multiplied by 100%, wherein: i-test mite number, and II-residual mite number.

(3) Mite killing test method: taking a glass jar, taking 3g of a test sample, adding 6L of water, and stirring until the test sample is completely dissolved; sewing non-woven fabric into 10cm × 10cm cloth bag, wrapping 100 mites therein, sealing, placing into the above glass jar, immersing into liquid, opening the stirrer to middle level, and stirring for 20 min. And taking out the cloth, observing, recording the number of the live mites and the number of the dead mites on the cloth, and calculating the acaricidal rate. The experiment was repeated 3 times. Control water was not supplemented with any test samples.

Calculating the formula:

the natural mortality rate N1 (%) (the number of mites before the experiment of the control group-the number of mites after the experiment of the control group)/the number of mites before the experiment of the control group multiplied by 100%;

acaricidal rate Kt (%) ([ number of mites before test sample experiment (1-natural mortality N1) ]number of mites after test sample experiment ]/number of mites before test sample experiment (1-natural mortality N1) × 100%.

TABLE 2 Deacarid, acarid killing efficacy test results

Sample (I)	Mite-killing rate	Acaricidal rate
			Example 1	95.3%	92.5%
Example 2	97.42%	94.81%
			Example 3	98.75%	95.54%
Example 4	99.37%	97.43%
			Example 5	98.36%	94.68%
Example 6	98.90%	96.43%
			Example 7	97.25%	91.43%
Example 8	98.57%	95.72%
			Example 9	100%	99.14%
Example 10	98.66%	94.92%
			Comparative example 1	52.45%	43.63%
Comparative example 2	59.57%	47.23%
			Comparative example 3	48.77%	39.82%
Comparative example 4	76.68%	64.53%

The experimental results in table 2 show that the mite removing and killing effects of the mite removing composition prepared by the invention are superior to those of the comparative examples, which shows that the mite removing and inhibiting effects of the mite removing extract prepared by the invention are better when the mite removing extract is applied to daily products, and the mite removing and inhibiting effects can obviously improve the symptoms of itch, acne, folliculitis and the like of skin caused by mites and restore the healthy skin state.

And (3) testing: test of bacteriostatic Effect

The compositions of examples 1 to 10 and comparative examples 1 to 4 of the present invention were tested for their bacteriostatic properties with reference to GB15979-2002 hygienic Standard for Disposable sanitary articles appendix C4 "test method for bacteriostatic Properties of leachable antibacterial products".

(1) Preparation of bacterial suspension: and washing the 24h culture of the propionibacterium acnes and the escherichia coli by using 0.03mol/L phosphate buffer solution to prepare 104-106 CFU/mL bacterial suspension.

(2) The compositions of examples 1-10, comparative examples 1-4 were formulated as 0.1% aqueous solutions. Respectively taking 1g of a sample to be tested, adding 0.1mL of the bacterial suspension, uniformly coating and mixing, starting timing, adding 9mL0.03mol/L of phosphate buffer solution after 20min, fully and uniformly mixing, taking 3 dilutions, respectively taking 1mL of the dilutions, placing the dilutions in two parallel plates, adding a corresponding culture medium, and culturing for 24 hours at 36 +/-1 ℃ under an anaerobic condition to count colonies. The above experiment was repeated 3 times, and the average was taken and a blank control group was set.

The calculation formula of the bacteriostatic rate is as follows: and X is (A-B)/A X100%, wherein X is the bacteriostasis rate, A is the average recovered colony of the control sample, and B is the average recovered colony of the test sample.

The evaluation standard of the acne removing efficacy is as follows: (1) the bacteriostatic rate is more than or equal to 90 percent; (2) the bacteriostasis rate is 50-90 percent, which is effective; (3) the bacteriostasis rate is less than 50 percent, which is ineffective.

The evaluation of bacteriostatic efficacy of the skin care products described in examples 1-10 and comparative examples 1-4 is shown in table 3.

TABLE 3 results of the bacteriostatic test of the compositions of the invention

Sample (I)	Propionibacterium acnes bacteriostasis rate	Antibacterial rate of Escherichia coli
			Example 1	86.19%	80.26%
Example 2	95.38%	88.79%
			Example 3	82.62%	81.49%
Example 4	90.71%	91.58%
			Example 5	91.23%	92.75%
Example 6	93.25%	92.71%
			Example 7	89.47%	85.48%
Example 8	94.27%	93.59%
			Example 9	95.67%	96.81%
Example 10	80.63%	83.20%
			Comparative example 1	48.36%	45.59%
Comparative example 2	50.38%	55.27%
			Comparative example 3	45.81%	46.54%
Comparative example 4	63.14%	59.39%

The composition has the antibacterial effect of over 80 percent and has better antibacterial effect. The bacteriostatic effect of the embodiments 2, 4, 5, 6, 8 and 9 can reach 90% or more, and the bacteriostatic rate effect is obvious. The bacteriostasis rate in the comparative example 1 and the comparative example 3 is lower than 50%, and the bacteriostasis is ineffective. Therefore, the bacteriostatic effect of the composition is far better than that of the comparative example.

And (4) testing: oxidation resistance test

This experiment evaluates the antioxidant properties of the compositions of the present invention by determining their ability to scavenge hydroxyl and superoxide radicals.

1) Test samples: the compositions of examples 1, 2, 3, 5, 7, 8, 9 and comparative examples 1, 2, 4 were diluted with ultrapure water to give a test solution with a mass fraction of 3%.

2) The test method comprises the following steps:

hydroxyl radical scavenging experiments: taking 0.5mL of absolute ethanol solution of o-diazaphenanthrene with the concentration of 0.75mmol/L into a test tube with a plug, respectively adding 2mL and 1mL of phosphate buffer solution with the pH of 7.4 and the concentration of 0.2mol/L into the test tube, fully and uniformly mixing the test samples, and adding 0.5mL of FeSO with the concentration of 0.75mmol/L into the test tube₄·7H₂O solution, mixed again and then added with 0.5mL of 0.01% (v/v) H₂O₂After being put in a constant-temperature water bath at 37 ℃ for 60min, the absorbance values of the mixed solutions are respectively measured at 536nm and recorded As As, and distilled water is used for replacingThe absorbance value of the sample solution as a blank is recorded as A_bReplacing H with distilled water₂O₂And measuring the absorbance value An of the damage group, and calculating the hydroxyl radical clearance of the test sample according to the following formula: hydroxyl radical clearance (%) = [ (As-An)/(a)_b-An)]X 100%, the average of three measurements was taken. The test results are shown in table 3.

Superoxide radical scavenging assay: adding 5mL of 50mmol/L pH8.2 phosphate buffer solution into a stoppered test tube at constant temperature of 25 deg.C, adding 0.2mL of preheated 50mmol/L pyrogallol, mixing immediately, and measuring absorbance A at 325nm every 30s₀Then, the measurement was carried out for 5 min. Respectively adding 1mL of sample solution, adding preheated 50mmol/L pyrogallol 0.2mL, immediately mixing, and measuring absorbance A₁The clearance rate was calculated according to the following formula: clearance% = (a)₀-A₁）/A₀100%. The average of three measurements was taken. The test results are shown in table 4.

TABLE 4 Oxidation resistance test results

As can be seen from the experimental results in Table 3, the compositions of the examples of the present invention have strong scavenging ability for hydroxyl radicals and superoxide radicals, while the comparative compositions have weak scavenging ability for free radicals, which indicates that the composition of the present invention can effectively scavenge active oxygen radicals, has good anti-oxidation effect, and reduces oxidative stress reaction during acne attack or other skin inflammations, thereby inhibiting acne and inflammatory reactions.

And testing: human body trial evaluation

(1) Test samples: the compositions of examples 2, 5, 8, 9 and comparative examples 3, 4 were added to a common emulsion base for external use to prepare respective emulsions.

(2) The test method comprises the following steps: volunteers with acne and inflammation on face, aged 18-32 years, were selected and divided into 6 groups of 30 persons, and the test samples were used respectively once in the morning and at night every day for 30 consecutive days.

The identification standard: the effect is more than 70% higher than that of acne elimination; ② the effective rate is more than 30% higher than that of acne; and the ratio of invalid to acne is less than 30%.

TABLE 5 human body test results

	Display effect (human)	Effective (human)	Invalid (human)
				Example 2	24	6	0
Example 5	22	8	0
				Example 8	26	4	0
Example 9	28	2	0
				Comparative example 3	8	12	10
Comparative example 4	13	9	8

As can be seen from the experimental results in Table 5, the emulsions of examples 2, 5, 8 and 9 are superior to the comparative examples in controlling sebum secretion and improving acne on the face, which shows that the combination of the components of the present invention produces a synergistic effect, which can effectively reduce the secretion of oil on the skin of the face and achieve a good effect of improving acne.

In conclusion, the natural active substances including the pelargonium roseum extract, the forsythia extract, the mint leaf extract, the sophora flavescens root extract, the rosemary extract and the sage extract are scientifically combined, so that sebum secretion can be well controlled through synergy, the antibacterial and anti-inflammatory effects can be achieved, active oxygen free radicals can be inhibited to achieve the antioxidant performance, and the skin acne and inflammation symptoms can be effectively improved when the cosmetic is applied to cosmetics.

The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, combinations, and simplifications are intended to be included in the scope of the present invention.

Claims

1. A multi-effect miticidal composition is characterized by comprising a pelargonium roseum extract, a fructus forsythiae extract, a mint leaf extract, a sophora flavescens root extract and a rosemary extract.

2. The soothing multi-effect acarus killing composition according to claim 1, wherein the composition comprises, by weight, 1-8 parts of pelargonium graveolens extract, 1-5 parts of forsythia suspensa extract, 1-5 parts of mint leaf extract, 0.5-3 parts of sophora flavescens root extract and 2-6 parts of rosemary extract.

3. The soothing multi-effect acarus killing composition according to claim 2, wherein the composition comprises, by weight, 2-7 parts of pelargonium graveolens extract, 2-4 parts of forsythia suspensa extract, 2-4 parts of mint leaf extract, 1-3 parts of sophora flavescens root extract and 3-5 parts of rosemary extract.

4. A soothing multipurpose mite killing composition according to claim 1 further comprising a sage extract.

5. The soothing multipurpose mite control composition of claim 4, wherein the ratio of the added amount of the sage extract to the mint leaf extract is 1-3: 1-3.

6. Use of a soothing multipurpose mite removing composition according to any one of claims 1 to 5, wherein the soothing multipurpose mite removing composition is used in the preparation of a daily necessity.

7. The use of a soothing multi-effect acarus killing composition according to claim 6, wherein the daily necessities comprise any one of soaps, water aqua, emulsion, cream, gel, mask daily necessities or washing and caring daily necessities.

8. The use of a soothing multipurpose mite removing composition according to claim 7, wherein the soothing multipurpose mite removing composition is added to the daily necessities in an amount of 0.01-25%.

9. The use of a soothing multipurpose mite removing composition according to claim 8, wherein the amount of the soothing multipurpose mite removing composition added to the daily necessities is 0.1-15%.