CN1152450A - Oral capsule Xianglianzi for contraception made of traditional Chinese medicine - Google Patents
Oral capsule Xianglianzi for contraception made of traditional Chinese medicine Download PDFInfo
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- CN1152450A CN1152450A CN 95118955 CN95118955A CN1152450A CN 1152450 A CN1152450 A CN 1152450A CN 95118955 CN95118955 CN 95118955 CN 95118955 A CN95118955 A CN 95118955A CN 1152450 A CN1152450 A CN 1152450A
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Abstract
The disclosed oral capsule for contraception is made up by compatibility of coumarona odorata, peach kernel, southern curcuma tuber, andrographis, Asian puccoon, psoralea fruit, whole Chinese angelica, Ligusticum wallichii, root of bidentate achyranthes, etc. 12 traditional Chinese medicinal herbs, which are weighed in accordance with the specific proportion and ground together into fine powder and filled intoc apsule to form the finished product. Through the clinical application of 301 cases the total effective rate can come up to 98%. Said drug features safety, reliable, low price and having no side effect.
Description
The present invention relates to the pure Chinese medicinal preparation that childbearing age woman contraceptive is used
China is a populous nation, practicing family planning is the fundamental state policy of China, in family planning work in the past, use steroid hormone class medicine to carry out contraceptives to the women of child-bearing age always, for example put intrauterine device, oral contraceptive, external contraceptive cover etc.In secular observation, find, adopt existing contraceptives can produce in various degree side effect human body.Particularly some is suffered from other disease and can not adopt existing contraceptives person very painful.Therefore, seek the new way of Chinese medicine contraception, become the task of top priority of medical circle.The present invention develops the Chinese medicine oral capsule Xianglianzi for contraception made of satisfactory effect groping and test through secular.
The object of the invention is, the Chinese medicine oral capsule Xianglianzi for contraception made of development is to have adopted 12 flavor Chinese medicines to make, through the 301 routine women of child-bearing age being taken clinical observation and following up a case by regular visits to, 200 examples in 25-30 year wherein, 101 examples in 36-40 year, total contraceptive rate is not all found any toxic and side effects more than 98%, this medicine taking convenience, safe and reliable, cheap, be the desirable medicine that pure Chinese medicine contraception is used in present family planning.
Task of the present invention is, the Chinese medicine oral capsule Xianglianzi for contraception made of development, 12 flavor Chinese medicines are distinguished pulverization in proportion, incapsulate, every capsules 0.4 gram, taking method: first day (or full back first day of term) after every menstrual phase begins to take medicine, serve on three, every day three times, each 2 grams, early, middle and late boiled water takes the purpose that can reach of that month contraception.
Chinese medicine oral capsule Xianglianzi for contraception made of the present invention, it mainly is made up of Herba Lysimachiae foenum-graeci, continuous core, Herba Spirodelae, Semen Persicae, RADIX CURCUMAE, Herba Andrographis, Radix Arnebiae (Radix Lithospermi), Fructus Psoraleae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Cyathulae, Herba Saussureae Involueratae, and its each medicine compatibility is: Herba Lysimachiae foenum-graeci 15-25 part, continuous core 10-20 part, Herba Spirodelae 5-15 part, Semen Persicae 5-15 part, RADIX CURCUMAE, 5-15 part, Herba Andrographis 5-15 part, Radix Arnebiae (Radix Lithospermi) 5-15 part, Fructus Psoraleae 5-15 part, Radix Angelicae Sinensis 5-15 part, Rhizoma Chuanxiong 5-12 part, Radix Cyathulae 5-12 part, Herba Saussureae Involueratae 1-5 part.Its method for production is: Herba Lysimachiae foenum-graeci, continuous core, Herba Spirodelae, Semen Persicae, RADIX CURCUMAE, Herba Andrographis, Radix Arnebiae (Radix Lithospermi), Fructus Psoraleae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Cyathulae, Herba Saussureae Involueratae are ground smalls respectively in proportion jointly, incapsulate, the vial sealing.
Chinese medicine oral capsule Xianglianzi for contraception made of the present invention, through the 301 routine women of child-bearing age are taken, wherein adhering to taking medicine in every month reaches 1 year person 175 people, responder 172 people that practise contraception, nonresponder 3 people.2 years person 100 people that adhere to taking medicine, contraception responder 98 people, nonresponder 2 people.3 years person 26 people that adhere to taking medicine, contraception responder 25 people, nonresponder 1 people, total effective rate 98%.To 301 routine women of child-bearing age pill taker long-term observation and following up a case by regular visits to, do not find any toxic and side effects, and reach anti-implantation simultaneously, the effect of antiearly pregnancy, and can keep women 's life, physiological function normal at period in a medicine.
Chinese medicine oral capsule Xianglianzi for contraception made of the present invention shows through the acute toxicity prediction experiment (L050) of animal and the trial test result of contraceptive pharmacy:
1, the acute toxicity trial test (L050) of Xianglianzi oral capsule
Take by weighing 10 of 10-20gNIH healthy mices, male and female half and half are divided into five groups of A, B, C, D, E, respectively dose are made into
A group dose is that 121mg/ B group dose is 84.7mg/ time
C group dose is that 60.5mg/ D group dose is 36.3mg/ time
E group dose is 12.1mg/ time
Mice is irritated stomach through fasting, taboo water after 2 hours, observe a week, see Table 1
| Group | Number of animals (only) | Death toll (only) |
| ????A ????B ????C ????D ????E | ????2 ????2 ????2 ????2 ????2 | ????--------------- ????--------------- ????--------------- ????--------------- ????--------------- |
2, the trial test of Xianglianzi oral capsule contraceptive pharmacodynamics
Take by weighing 10 of the healthy male and female mices of 25-28g and be divided into five groups of A, B, C, D, E, make up a prescription respectively into:
A group 3.8mg/ml B group 3mg/ml
C group 2.4mg/ml D group 2mg/ml
E organizes 1.6mg/ml
To mice fasting water after 2 hours, to irritate stomach and took medicine continuously 5 days, administration volume 0.5ml/ Mus is after mating 7 days entirely by female two heros in second day that stops, and anatomic observation gestation situation sees Table 2
| Group | Number of animals (only) | Death toll (only) |
| ????A ????B ????C ????D ????E | ????2 ????2 ????2 ????2 ????2 | ?????____ ?????____ ?????____ ?????1 ?????____ |
As can be seen from Table 1, this poison of drug of Xianglianzi L050 trial test is less, and Xianglianzi plays the effect of contraception in the Chinese medicine contraceptive as can be seen from Table 2, so Chinese medicine oral capsule Xianglianzi for contraception made of the present invention, the mutual compatibility of medicine, the property of medicine is coordinated, and cold and heat help mutually, through-supplementation, promptly abide by the style of ancient matter modelled after an antique, meet the principle of Modern Pharmaceutical Chemistry again, can reach contraception and not hinder healthy energy, set upright and do not hinder contraceptive effect, thereby have the good action of anti-implantation, antiearly pregnancy.
Embodiment 1:
It is even to take by weighing 15 parts of Herba Lysimachiae foenum-graeci, 20 parts of continuous core, 10 parts of Herba Spirodelae, 5 parts in Semen Persicae, 15 parts of RADIX CURCUMAEs, 15 parts of Herba Andrographis, 10 parts of Radix Arnebiae (Radix Lithospermi)s, 5 parts of Fructus Psoraleaes, 5 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiongs, 12 parts of Radix Cyathulaes, 5 parts of mixed together of Herba Saussureae Involueratae, grind smalls, incapsulate, every capsules 0.4 gram, the vial sealing gets final product, and every menstrual phase is use up back first day (or term is completely back) and is begun to take medicine, serve on three, every day three times, each 2 grams, boiled water drug delivery.
Embodiment 2:
It is even to take by weighing 25 parts of Herba Lysimachiae foenum-graeci, 10 parts of continuous core, 5 parts of Herba Spirodelae, 10 parts in Semen Persicae, 10 parts of RADIX CURCUMAEs, 5 parts of Herba Andrographis, 15 parts of Radix Arnebiae (Radix Lithospermi)s, 10 parts of Fructus Psoraleaes, 10 parts of Radix Angelicae Sinensis, 5 parts of Rhizoma Chuanxiongs, 10 parts of Radix Cyathulaes, 3 parts of mixed together of Herba Saussureae Involueratae, grind smalls, incapsulate, every capsules 0.4 gram, the vial sealing gets final product, and every menstrual phase is use up back first day (or term is completely back) and is begun to take medicine, serve on three, every order three times, each 2 grams, boiled water drug delivery.
Embodiment 3:
It is even to take by weighing 20 parts of Herba Lysimachiae foenum-graeci, 15 parts of continuous core, 15 parts of Herba Spirodelae, 15 parts in Semen Persicae, 5 parts of RADIX CURCUMAEs, 10 parts of Herba Andrographis, 5 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Fructus Psoraleaes, 15 parts of Radix Angelicae Sinensis, 12 parts of Rhizoma Chuanxiongs, 5 parts of Radix Cyathulaes, 10 parts of mixed together of Herba Saussureae Involueratae, grind smalls, incapsulate, every capsules 0.4 gram, the vial sealing gets final product, and every menstrual phase is use up back first day (or term is completely back) and is begun to take medicine, serve on three, every day three times, each 2 grams, boiled water drug delivery.
Claims (2)
1, a kind of Chinese medicine oral capsule Xianglianzi for contraception made that is used for contraception of woman, it is characterized in that, it is made up of Herba Lysimachiae foenum-graeci, continuous core, Herba Spirodelae, Semen Persicae, RADIX CURCUMAE, Herba Andrographis, Radix Arnebiae (Radix Lithospermi), Fructus Psoraleae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Cyathulae, Herba Saussureae Involueratae, and its each medicine compatibility is:
Herba Lysimachiae foenum-graeci 15-25 part, continuous core 10-20 part, Herba Spirodelae 5-15 part, Semen Persicae 5-15 part, RADIX CURCUMAE, 5-15 part, Herba Andrographis 5-15 part, Radix Arnebiae (Radix Lithospermi) 5-15 part, Fructus Psoraleae 5-15 part, Radix Angelicae Sinensis 5-15 part, Rhizoma Chuanxiong 5-12 part, Radix Cyathulae 5-12 part, Herba Saussureae Involueratae 1-10 part.
2, Chinese medicine oral capsule Xianglianzi for contraception made according to claim 1, it is characterized in that, Herba Lysimachiae foenum-graeci, continuous core, Herba Spirodelae, Semen Persicae, RADIX CURCUMAE, Herba Andrographis, Radix Arnebiae (Radix Lithospermi), Fructus Psoraleae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Cyathulae, Herba Saussureae Involueratae are ground smalls respectively in proportion jointly, incapsulate the vial sealing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN95118955A CN1057921C (en) | 1995-12-08 | 1995-12-08 | Oral capsule Xianglianzi for contraception made of traditional Chinese medicine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN95118955A CN1057921C (en) | 1995-12-08 | 1995-12-08 | Oral capsule Xianglianzi for contraception made of traditional Chinese medicine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1152450A true CN1152450A (en) | 1997-06-25 |
| CN1057921C CN1057921C (en) | 2000-11-01 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN95118955A Expired - Fee Related CN1057921C (en) | 1995-12-08 | 1995-12-08 | Oral capsule Xianglianzi for contraception made of traditional Chinese medicine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1057921C (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1084402A (en) * | 1992-09-21 | 1994-03-30 | 王暑轸 | Chinese traditional medicinal contraceptive pellet |
| CN1090498A (en) * | 1993-02-01 | 1994-08-10 | 杨芳林 | Lady's oral contraception Chinese patent medicine and preparation method |
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1995
- 1995-12-08 CN CN95118955A patent/CN1057921C/en not_active Expired - Fee Related
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| Publication number | Publication date |
|---|---|
| CN1057921C (en) | 2000-11-01 |
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