CN112370378A - Cosmetic containing guayule troponin stock solution and preparation method thereof - Google Patents
Cosmetic containing guayule troponin stock solution and preparation method thereof Download PDFInfo
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- CN112370378A CN112370378A CN202010856668.1A CN202010856668A CN112370378A CN 112370378 A CN112370378 A CN 112370378A CN 202010856668 A CN202010856668 A CN 202010856668A CN 112370378 A CN112370378 A CN 112370378A
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- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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Abstract
The invention relates to the technical field of cosmetics, and relates to a cosmetic of a gelsemium elegans collagen stock solution type and a preparation method thereof, wherein the cosmetic of the stock solution type comprises 50-55 parts of a group A raw material and 20-32 parts of a collagen promoting group raw material; the collagen promoting group raw material comprises a plukenetia volubilis linneo component, and the plukenetia volubilis linneo component is plukenetia volubilis linneo oil and/or plukenetia volubilis linneo oil microemulsion; the group A raw materials comprise the following components in parts by weight: 45-50 parts of water, 1-2 parts of corn gluten amino acids, 2-3 parts of trehalose and 3-3.5 parts of butanediol. The invention has the beneficial effects that: can effectively supplement skin collagen, activate the powerful function of cell regeneration, merge biological transdermal technology, deeply repair skin, have strong activity and high absorption rate, solve various skin problems and restore the young state of skin.
Description
Technical Field
The invention relates to the technical field of cosmetics, and particularly relates to a cosmetic containing a gelsemium elegans collagen stock solution and a preparation method thereof.
Background
The aging of human body is the inevitable rule of life growth, wherein the change of skin is most obvious, the skin of a common female tends to slide down after the age of 25, and the aging is early after the age of 30. Skin aging refers to the rough surface and appearance of wrinkles. Skin aging is a progressive physiological process and also a result of the combined action of various factors such as heredity, environment, psychology and the like.
Collagen is the main component of skin tissue, accounts for more than 70% of the protein content in skin cells, and after the collagen in the tissue is lost, the skin loses elasticity, wrinkles, color spots and other aging phenomena occur. The nutrition and repair function of collagen for timely supplementing skin to human skin is more and more paid more attention by the beauty industry.
At present, most of the collagen cosmetics popular in the market adopt macromolecular collagen, and the skin feels thick, heavy, sticky and greasy due to poor compatibility of a formula, so that the skin is difficult to absorb through skin, the skin burden is increased, and the skin breathability is also deteriorated, so that the skin problems of different degrees can be caused by factors such as allergic constitution, environmental change, nervous life and work rhythm, unbalanced diet, abnormal life and rest, night stay and the like.
Disclosure of Invention
In order to solve the problems, the invention provides the plukenetia volubilis linneo troponin stoste cosmetic and the preparation method thereof, the plukenetia volubilis linneo component, the hydrolyzed collagen with the molecular weight of 350-plus 500Da, the palmitoyl tripeptide-5, the chlorella deep repair factor, the glycerol glucoside, the chamomile extract, the peony root extract and other components are matched, the problem that macromolecular collagen is difficult to be absorbed through the skin through skin is solved, the skin collagen is effectively supplemented, the powerful function of cell regeneration is activated, the skin is deeply repaired, and the skin elasticity is restored.
The technical scheme of the invention is as follows: a cosmetic of the protocollagen of the cambogia is characterized in that: the composite material comprises the following raw materials in parts by mass: 50-55 parts of group A raw material and 20-32 parts of collagen-promoting group raw material
Further, the collagen promoting group raw material comprises a plukenetia volubilis linneo component, and the plukenetia volubilis linneo component is plukenetia volubilis linneo oil and/or plukenetia volubilis linneo oil microemulsion.
Further, the collagen group promoting raw material also comprises one or more of squalane, snail secretion filtrate, coenzyme Q10 and evening primrose essential oil.
Further, the collagen group promoting raw material comprises the following components in parts by weight: 10-13 parts of plukenetia volubilis linneo oil, 3-4.5 parts of squalane, 2-4.5 parts of snail secretion filtrate, 104.5-5 parts of coenzyme Q and 2.5-3 parts of evening primrose essential oil.
Further, the group A raw materials comprise the following components in parts by weight: 45-50 parts of water, 1-2 parts of corn gluten amino acids, 2-3 parts of trehalose and 3-3.5 parts of butanediol.
Further, the cosmetic of the acerola and royal jelly raw liquid also comprises 3-3.8 parts of group B raw materials, wherein the group B raw materials comprise the following components in parts by weight: 2.5 to 3.5 portions of 1, 3-propylene glycol and 0.35 to 0.65 portion of polyacrylate cross-linked polymer-6.
Furthermore, the cosmetic of the acerola and royal jelly raw liquid also comprises 3.0 to 3.8 parts of group C raw materials, wherein the group C raw materials comprise the following components in parts by weight: 2.5-3.5 parts of 1, 3-propylene glycol and 0.35-0.65 part of p-hydroxyacetophenone.
Further, the cosmetic of the acerola and royal jelly raw liquid also comprises 6-8 parts of a group D raw material, wherein the group D raw material comprises the following components in parts by weight: 0.5-0.8 part of panthenol, 4-7 parts of glycerol glucoside, 1-1.5 parts of golden chamomile extract/mint leaf extract/pelargonium graveolens extract/purslane extract/aloe barbadensis leaf extract/sophora flavescens root extract, 1-1.5 parts of peony root extract/loquat leaf extract/selaginella tamariscina extract/cacumen biotae extract and 0.4-0.7 part of 1, 2-hexanediol.
Further, the cosmetic of the acerola and royal jelly raw liquid also comprises 30-40 parts of group E raw materials, wherein the group E raw materials comprise the following components in parts by weight: 4.5-6.5 parts of chlorella deep repair factor, 5.0-8.0 parts of palmitoyl tripeptide-5 parts and 20-30 parts of hydrolyzed collagen.
A preparation method of cosmetic of guayule troponin stock solution is characterized in that: the method comprises the following steps:
step one, sequentially adding the group A raw materials and the collagen promotion raw materials into a batching pot, stirring and heating to 85-90 ℃ to completely dissolve, keeping the temperature for 30 minutes, and stirring at the rotating speed of 25-30 rpm;
step two, mixing and dispersing the raw materials of the group B, adding the mixture into a mixing pot, stirring and homogenizing until the mixture is completely dissolved, wherein the stirring speed is 35-38 rpm;
step three, continuously cooling and stirring the temperature of the batching pot in the step two to 55-60 ℃, adding the pre-dissolved C group raw materials and uniformly stirring, wherein the stirring speed is 20-25 rpm;
step four, cooling and stirring the temperature of the mixing pot in the step three to 38-42 ℃, adding the raw materials in the group D, and uniformly stirring at the stirring speed of 18-20rpm to finish the preparation.
Further, before the first step, a pretreatment step is further included, and the pretreatment step specifically refers to: thoroughly cleaning and sterilizing production equipment, and calibrating the production equipment;
and/or
A detection step is further included after the fifth step, wherein the detection step specifically refers to: stopping the machine, sampling and detecting, and filtering and discharging after the detection is qualified.
The invention has the beneficial effects that: the formula is reasonable in design, the formula of the stock solution comprises 50-55 parts of the group A raw material, 3-3.8 parts of the group B raw material, 3.0-3.8 parts of the group C raw material, 6-8 parts of the group D raw material, 28-35 parts of the group E raw material and the collagen promotion raw material, and specifically adopts hydrolyzed collagen with the molecular weight of 350-500Da, and is matched with components such as palmitoyl tripeptide-5, chlorella deep repair factor, glycerol glucoside, chamomile extract, peony root extract and the like, so that the problem that macromolecular collagen is difficult to be absorbed through the skin is solved, the skin collagen is effectively supplemented, the powerful function of cell regeneration is activated, the skin is deeply repaired, and the skin elasticity is restored.
The invention also provides a preparation method of the cosmetic of the protogen of the cambogia and cambogia prepared by the method, the protogen of the cambogia prepared by the method can effectively supplement skin collagen, overcome the problem that macromolecular collagen is difficult to be absorbed through skin penetration, activate the powerful function of cell regeneration, deeply repair skin, solve the problems of various skins and restore the elasticity of the skin.
Drawings
FIG. 1 is a flow chart of the method for preparing cosmetic of the present invention;
FIG. 2 is a photograph of in vitro test I for skin repair and reconstruction of cosmetic skin preparations of the cosmetic of the beauty-vine fruit and imperial myocollagen of the invention;
FIG. 3 is a photograph of in vitro test II for skin repair and reconstruction of cosmetic skin preparations of the cosmetic of the present invention;
FIG. 4 is a photograph of in vitro test III of skin repair and reconstruction of cosmetic skin preparations of the cosmetic of the present invention;
FIG. 5 is a photograph of the skin repair and reconstruction in vivo test of the cosmetic of the present invention;
Detailed Description
The detailed description of the cosmetic of the present invention and the preparation method thereof will be made with reference to the accompanying drawings and examples.
The technical scheme of the invention is as follows: the cosmetic for the protocollagen of the cambogia comprises the following raw materials in parts by mass: 50-55 parts of group A raw material and 20-32 parts of procollagen raw material.
The collagen promoting group raw material comprises a plukenetia volubilis linneo component, and the plukenetia volubilis linneo component is plukenetia volubilis linneo oil and/or plukenetia volubilis linneo oil microemulsion.
The plukenetia volubilis linneo, the academic name plukenetia volubilis linneo, belongs to perennial woody liana plants of the euphorbiaceae family, and grows in tropical rainforests in south America Andes mountain areas with the altitude of 80-1700 m. In the end of 2008, Puer integrated biological resource development limited company in Yunnan province starts to introduce provenance, and the Puer is planted in Puer city and Xishuangbanna in 2009 and is mainly distributed in Puer and Xishuangbanna areas and the like, and the planting area reaches more than 5 ten thousand mu. The plukenetia volubilis linneo nut is rich in nutrition, is rich in protein, unsaturated fatty acid, vitamin E, calcium, phosphorus, iron and other mineral substances, has important functional effects in the aspects of promoting bone growth and nervous system development, beautifying and resisting aging, improving digestive system functions, preventing cardiovascular diseases, preventing cancers, preventing diabetes and the like, and has formal notice of plukenetia volubilis linneo oil as a national new resource food in 2013 in 1 month.
The Plukenetia volubilis linneo oil is prepared by cold pressing and primary pressing, wherein the cold pressing and primary pressing process comprises the steps of selecting seeds, cleaning, drying, shelling, crushing, cold pressing once and filtering. The vegetable oil prepared by the cold pressing preliminary pressing mode is different from the refined vegetable oil, the cold pressing preliminary pressing vegetable seed oil contains more unsaturated oil, various vitamins such as sterol, carotene, plant flavone, plant polyphenol and the like, has the effect of promoting the generation of hyaluronic acid, collagen and elastin of the skin, can keep the skin elastic, keep away from wrinkles and present a healthy and young skin state.
The microemulsion is a transparent or semitransparent solution system which is formed spontaneously by a water phase, an oil phase, a surfactant and a cosurfactant according to a proper proportion, has low viscosity, isotropy and stable thermodynamics and has a particle size of 10-100 nm. The microemulsion has the advantages of good stability, simple operation, high bioavailability, etc., and can increase the solubility of plant essential oil in water.
The collagen promoting raw material also comprises one or more of squalane, snail secretion filtrate, coenzyme Q10, and evening primrose essential oil.
The collagen promoting group raw material comprises the following components in parts by weight: 10-13 parts of plukenetia volubilis linneo oil, 3-4.5 parts of squalane, 2-4.5 parts of snail secretion filtrate, 104.5-5 parts of coenzyme Q and 2.5-3 parts of evening primrose essential oil.
The group A raw materials comprise the following components in parts by weight: 45-50 parts of water, 1-2 parts of corn gluten amino acids, 2-3 parts of trehalose and 3-3.5 parts of butanediol.
The cosmetic also comprises 3-3.8 parts of group B raw materials, wherein the group B raw materials comprise the following components in parts by weight: 2.5 to 3.5 portions of 1, 3-propylene glycol and 0.35 to 0.65 portion of polyacrylate cross-linked polymer-6.
The cosmetic also comprises 3.0-3.8 parts of group C raw materials, wherein the group C raw materials comprise the following components in parts by weight: 2.5-3.5 parts of 1, 3-propylene glycol and 0.35-0.65 part of p-hydroxyacetophenone.
The cosmetic also comprises 6-8 parts of group D raw materials, wherein the group D raw materials comprise the following components in parts by weight: 0.5-0.8 part of panthenol, 4-7 parts of glycerol glucoside, 1-1.5 parts of golden chamomile extract/mint leaf extract/pelargonium graveolens extract/purslane extract/aloe barbadensis leaf extract/sophora flavescens root extract, 1-1.5 parts of peony root extract/loquat leaf extract/selaginella tamariscina extract/cacumen biotae extract and 0.4-0.7 part of 1, 2-hexanediol.
The cosmetic also comprises 30-40 parts of group E raw materials, wherein the group E raw materials comprise the following components in parts by weight: 4.5-6.5 parts of chlorella deep repair factor, 5.0-8.0 parts of palmitoyl tripeptide-5 parts and 20-30 parts of hydrolyzed collagen.
A cosmetic of the protocollagen of the cambogia comprises the following steps:
step one, sequentially adding the group A raw materials and the whitening raw materials into an ingredient pot, stirring and heating to 85-90 ℃ to completely dissolve, keeping the temperature for 30 minutes, and stirring at the rotating speed of 25-30 rpm;
step two, mixing and dispersing the raw materials of the group B, adding the mixture into a mixing pot, stirring and homogenizing until the mixture is completely dissolved, wherein the stirring speed is 35-38 rpm;
step three, continuously cooling and stirring the temperature of the batching pot in the step two to 55-60 ℃, adding the pre-dissolved C group raw materials and uniformly stirring, wherein the stirring speed is 20-25 rpm;
step four, cooling and stirring the temperature of the mixing pot in the step three to 38-42 ℃, adding the group D raw materials and uniformly stirring, wherein the stirring speed is 18-20 rpm;
step five, cooling and stirring the temperature of the batching pot in the step four to 35-38 ℃, adding the raw materials of the group E, and uniformly stirring at the stirring speed of 15-18rpm to finish the preparation.
Further, before the first step, a pretreatment step is further included, and the pretreatment step specifically refers to: thoroughly cleaning and sterilizing production equipment, and calibrating the production equipment;
and/or
A detection step is further included after the fifth step, wherein the detection step specifically refers to: stopping the machine, sampling and detecting, and filtering and discharging after the detection is qualified.
The formula of the stock solution is reasonable in design, the formula of the stock solution comprises 50-55 parts of group A raw materials, 3-3.8 parts of group B raw materials, 3.0-3.8 parts of group C raw materials, 6-8 parts of group D raw materials, 28-35 parts of group E raw materials and collagen promotion raw materials, specifically hydrolyzed collagen with the molecular weight of 350-.
The invention also provides a preparation method of the cosmetic of the protogen of the cambogia and cambogia prepared by the method, the protogen of the cambogia prepared by the method can effectively supplement skin collagen, overcome the problem that macromolecular collagen is difficult to be absorbed through skin penetration, activate the powerful function of cell regeneration, deeply repair skin, solve the problems of various skins and restore the elasticity of the skin.
Example 1
The cosmetic for the protocollagen of the cambogia comprises the following raw materials in parts by mass: 50-55 parts of group A raw material and 20-32 parts of procollagen raw material.
Example 2
A cosmetic of the protocollagen of the cambogia is characterized in that: the composite material comprises the following raw materials in parts by mass: 50-55 parts of group A raw material and 20-32 parts of procollagen raw material.
The collagen promoting group raw material comprises a plukenetia volubilis linneo component, and the plukenetia volubilis linneo component is plukenetia volubilis linneo oil and/or plukenetia volubilis linneo oil microemulsion.
The collagen promoting group raw material comprises a plukenetia volubilis linneo component, and the plukenetia volubilis linneo component is plukenetia volubilis linneo oil and/or plukenetia volubilis linneo oil microemulsion.
The plukenetia volubilis linneo, the academic name plukenetia volubilis linneo, belongs to perennial woody liana plants of the euphorbiaceae family, and grows in tropical rainforests in south America Andes mountain areas with the altitude of 80-1700 m. In the end of 2008, Puer integrated biological resource development limited company in Yunnan province starts to introduce provenance, and the Puer is planted in Puer city and Xishuangbanna in 2009 and is mainly distributed in Puer and Xishuangbanna areas and the like, and the planting area reaches more than 5 ten thousand mu. The plukenetia volubilis linneo nut is rich in nutrition, is rich in protein, unsaturated fatty acid, vitamin E, calcium, phosphorus, iron and other mineral substances, has important functional effects in the aspects of promoting bone growth and nervous system development, beautifying and resisting aging, improving digestive system functions, preventing cardiovascular diseases, preventing cancers, preventing diabetes and the like, and has formal notice of plukenetia volubilis linneo oil as a national new resource food in 2013 in 1 month.
The Plukenetia volubilis linneo oil is prepared by cold pressing and primary pressing, wherein the cold pressing and primary pressing process comprises the steps of selecting seeds, cleaning, drying, shelling, crushing, cold pressing once and filtering. The vegetable oil prepared by the cold pressing preliminary pressing mode is different from the refined vegetable oil, the cold pressing preliminary pressing vegetable seed oil contains more unsaturated oil, various vitamins such as sterol, carotene, plant flavone, plant polyphenol and the like, has the effect of promoting the generation of hyaluronic acid, collagen and elastin of the skin, can keep the skin elastic, keep away from wrinkles and present a healthy and young skin state.
The microemulsion is a transparent or semitransparent solution system which is formed spontaneously by a water phase, an oil phase, a surfactant and a cosurfactant according to a proper proportion, has low viscosity, isotropy and stable thermodynamics and has a particle size of 10-100 nm. The microemulsion has the advantages of good stability, simple operation, high bioavailability, etc., and can increase the solubility of plant essential oil in water.
Example 3
A cosmetic of the protocollagen of the cambogia is characterized in that: the composite material comprises the following raw materials in parts by mass: 50-55 parts of group A raw material and 20-32 parts of procollagen raw material.
The collagen promoting group raw material comprises a plukenetia volubilis linneo component, and the plukenetia volubilis linneo component is plukenetia volubilis linneo oil and/or plukenetia volubilis linneo oil microemulsion.
The collagen promoting group raw material comprises a plukenetia volubilis linneo component, and the plukenetia volubilis linneo component is plukenetia volubilis linneo oil and/or plukenetia volubilis linneo oil microemulsion.
The plukenetia volubilis linneo, the academic name plukenetia volubilis linneo, belongs to perennial woody liana plants of the euphorbiaceae family, and grows in tropical rainforests in south America Andes mountain areas with the altitude of 80-1700 m. In the end of 2008, Puer integrated biological resource development limited company in Yunnan province starts to introduce provenance, and the Puer is planted in Puer city and Xishuangbanna in 2009 and is mainly distributed in Puer and Xishuangbanna areas and the like, and the planting area reaches more than 5 ten thousand mu. The plukenetia volubilis linneo nut is rich in nutrition, is rich in protein, unsaturated fatty acid, vitamin E, calcium, phosphorus, iron and other mineral substances, has important functional effects in the aspects of promoting bone growth and nervous system development, beautifying and resisting aging, improving digestive system functions, preventing cardiovascular diseases, preventing cancers, preventing diabetes and the like, and has formal notice of plukenetia volubilis linneo oil as a national new resource food in 2013 in 1 month.
The Plukenetia volubilis linneo oil is prepared by cold pressing and primary pressing, wherein the cold pressing and primary pressing process comprises the steps of selecting seeds, cleaning, drying, shelling, crushing, cold pressing once and filtering. The vegetable oil prepared by the cold pressing preliminary pressing mode is different from the refined vegetable oil, the cold pressing preliminary pressing vegetable seed oil contains more unsaturated oil, various vitamins such as sterol, carotene, plant flavone, plant polyphenol and the like, has the effect of promoting the generation of hyaluronic acid, collagen and elastin of the skin, can keep the skin elastic, keep away from wrinkles and present a healthy and young skin state.
The microemulsion is a transparent or semitransparent solution system which is formed spontaneously by a water phase, an oil phase, a surfactant and a cosurfactant according to a proper proportion, has low viscosity, isotropy and stable thermodynamics and has a particle size of 10-100 nm. The microemulsion has the advantages of good stability, simple operation, high bioavailability, etc., and can increase the solubility of plant essential oil in water.
The collagen promoting raw material also comprises one or more of squalane, snail secretion filtrate, coenzyme Q10, and evening primrose essential oil.
The collagen promoting group raw material comprises the following components in parts by weight: 10-13 parts of plukenetia volubilis linneo oil, 3-4.5 parts of squalane, 2-4.5 parts of snail secretion filtrate, 104.5-5 parts of coenzyme Q and 2.5-3 parts of evening primrose essential oil.
Example 4
The technical scheme of the method comprises the following technical scheme in addition to any one of the technical schemes 1 to 3:
the group A raw materials comprise the following components in parts by weight: 45-50 parts of water, 1-2 parts of corn gluten amino acids, 2-3 parts of trehalose and 3-3.5 parts of butanediol.
Example 5
Besides any technical scheme of 1-4, the method also comprises the following technical scheme:
the cosmetic also comprises 3-3.8 parts of group B raw materials, wherein the group B raw materials comprise the following components in parts by weight: 2.5 to 3.5 portions of 1, 3-propylene glycol and 0.35 to 0.65 portion of polyacrylate cross-linked polymer-6.
Example 6
Besides any technical scheme of 1-5, the method also comprises the following technical scheme:
the cosmetic also comprises 3.0-3.8 parts of group C raw materials, wherein the group C raw materials comprise the following components in parts by weight: 2.5-3.5 parts of 1, 3-propylene glycol and 0.35-0.65 part of p-hydroxyacetophenone.
Example 7
Besides any technical scheme of 1-6, the method also comprises the following technical scheme:
the cosmetic also comprises 6-8 parts of group D raw materials, wherein the group D raw materials comprise the following components in parts by weight: 0.5-0.8 part of panthenol, 4-7 parts of glycerol glucoside, 1-1.5 parts of golden chamomile extract/mint leaf extract/pelargonium graveolens extract/purslane extract/aloe barbadensis leaf extract/sophora flavescens root extract, 1-1.5 parts of peony root extract/loquat leaf extract/selaginella tamariscina extract/cacumen biotae extract and 0.4-0.7 part of 1, 2-hexanediol.
Example 9
Besides any technical scheme of 1-7, the method also comprises the following technical scheme:
the cosmetic also comprises 30-40 parts of group E raw materials, wherein the group E raw materials comprise the following components in parts by weight: 4.5-6.5 parts of chlorella deep repair factor, 5.0-8.0 parts of palmitoyl tripeptide-5 parts and 20-30 parts of hydrolyzed collagen.
Example 10
A preparation method of cosmetic of guayule troponin stock solution comprises the following steps:
step 101, sequentially adding the group A raw materials and the collagen promotion raw materials into a batching pot, stirring and heating to 85-90 ℃ for complete dissolution, keeping the temperature for 30 minutes, and stirring at the rotating speed of 25-30 rpm;
102, mixing and dispersing the raw materials of the group B, adding the mixture into a mixing pot, stirring and homogenizing until the mixture is completely dissolved, wherein the stirring speed is 35-38 rpm;
step 103, continuously cooling and stirring the temperature of the dosing pot in the step 102 to 55-60 ℃, adding the pre-dissolved C group raw materials, and uniformly stirring at the stirring speed of 20-25 rpm;
step 104, cooling and stirring the temperature of the batching pot in the step 103 to 38-42 ℃, adding the group D raw materials, and uniformly stirring at the stirring speed of 18-20 rpm;
and 105, cooling and stirring the temperature of the dosing pot in the step 104 to 35-38 ℃, adding the raw materials of the group E, and uniformly stirring at the stirring speed of 15-18rpm to finish the preparation.
Example 11
A preparation method of cosmetic of guayule troponin stock solution comprises the following steps:
step 201: thoroughly cleaning and sterilizing production equipment, and calibrating the production equipment;
202, sequentially adding the group A raw materials and the collagen promotion raw materials into a batching pot, stirring and heating to 85-90 ℃ to completely dissolve, keeping the temperature for 30 minutes, and stirring at the rotating speed of 25-30 rpm;
step 203, mixing and dispersing the raw materials of the group B, adding the mixture into a mixing pot, stirring and homogenizing until the mixture is completely dissolved, wherein the stirring speed is 35-38 rpm;
step 204, continuously cooling and stirring the temperature of the dosing pot in the step 203 to 55-60 ℃, adding the pre-dissolved C group raw materials, and uniformly stirring at the stirring speed of 20-25 rpm;
step 205, cooling and stirring the temperature of the batching pot in the step 204 to 38-42 ℃, adding the raw materials in the group D, and uniformly stirring at the stirring speed of 18-20 rpm;
and step 206, cooling and stirring the temperature of the dosing pot in the step 205 to 35-38 ℃, adding the raw materials of the group E, and uniformly stirring at the stirring speed of 15-18rpm to finish the preparation.
Example 12
A preparation method of cosmetic of guayule troponin stock solution comprises the following steps:
301, sequentially adding the group A raw materials and the collagen promotion raw materials into a batching pot, stirring and heating to 85-90 ℃ to completely dissolve, keeping the temperature for 30 minutes, and stirring at the rotating speed of 25-30 rpm;
step 302, mixing and dispersing the raw materials of the group B, adding the mixture into a mixing pot, stirring and homogenizing until the mixture is completely dissolved, wherein the stirring speed is 35-38 rpm;
step 303, continuously cooling and stirring the temperature of the batching pot in the step 302 to 55-60 ℃, adding the pre-dissolved C group raw materials, and uniformly stirring at the stirring speed of 20-25 rpm;
step 304, cooling and stirring the temperature of the batching pot in the step 303 to 38-42 ℃, adding the raw materials in the group D, and uniformly stirring at the stirring speed of 18-20 rpm;
step 305, cooling and stirring the temperature of the batching pot in the step five to 35-38 ℃, adding the raw materials of the group E, and uniformly stirring at the stirring speed of 15-18rpm to finish the preparation;
and step 306, stopping the machine after the preparation is finished, sampling and detecting, filtering and discharging after the detection is qualified.
Example 13
A preparation method of cosmetic of guayule troponin stock solution comprises the following steps:
step 401: thoroughly cleaning and sterilizing production equipment, and calibrating the production equipment;
step 402, adding the group A raw materials and the collagen promotion raw materials into a batching pot in sequence, stirring and heating to 85-90 ℃ for complete dissolution, keeping the temperature for 30 minutes, and stirring at the rotating speed of 25-30 rpm;
step 403, mixing and dispersing the raw materials of the group B, adding the mixture into a mixing pot, stirring and homogenizing until the mixture is completely dissolved, wherein the stirring speed is 35-38 rpm;
step 404, continuously cooling and stirring the temperature of the batching pot in the step 403 to 55-60 ℃, adding the pre-dissolved C group raw materials, and uniformly stirring at the stirring speed of 20-25 rpm;
step 405, cooling and stirring the temperature of the batching pot in the step 404 to 38-42 ℃, adding the group D raw materials, and uniformly stirring at the stirring speed of 18-20 rpm;
step 406, cooling and stirring the temperature of the batching pot in the step 405 to 35-38 ℃, adding the raw materials of the group E, and uniformly stirring at the stirring speed of 15-18rpm to finish the preparation;
and 407, stopping the machine for sampling and detecting after the preparation is finished, and filtering and discharging after the detection is qualified.
Example 14
The cosmetic comprises the following components in parts by mass:
the preparation method of the cosmetic of the protocollagen of the cambogia comprises the following steps:
1. thoroughly cleaning and sterilizing production equipment, and calibrating the production equipment;
2. sequentially adding the group A raw materials and the collagen-promoting group raw materials into a batching pot, stirring and heating to 85-90 ℃ for complete dissolution, keeping the temperature for 30 minutes, and stirring at the rotating speed of 25-30 rpm;
3. cooling and stirring the temperature of the batching pot in the step 2 to 80-85 ℃, adding the raw materials of the group B, stirring and homogenizing until the raw materials are completely dissolved and transparent, and stirring at the rotating speed of 30-35 rpm;
4. continuously cooling and stirring the temperature of the batching kettle in the step 3 to 55-60 ℃, adding the pre-dissolved C group raw materials, and uniformly stirring at the stirring speed of 20-25 rpm;
5. cooling and stirring the temperature of the batching pot in the step 4 to 38-42 ℃, adding the raw materials of the group D, and uniformly stirring at the stirring speed of 18-20 rpm;
6. cooling and stirring the temperature of the batching pot in the step 5 to 35-38 ℃, adding the raw materials of the group E, and uniformly stirring at the stirring speed of 15-18rpm to finish the preparation;
7. stopping the machine, sampling and detecting, and filtering and discharging after the detection is qualified.
Comparative test
FIG. 2 is a photograph of in vitro test I for skin repair and reconstruction of cosmetic skin preparations of the cosmetic of the beauty-vine fruit and imperial myocollagen of the invention;
the cosmetic of the protocollagen of the cambogia increases 333 percent of the collagen 1; increasing the collagen type 3 by 155 percent.
FIG. 3 is a photograph of in vitro test II for skin repair and reconstruction of cosmetic skin preparations of the cosmetic of the present invention;
cosmetic compositions of the guayule troponin stock increase elastin synthesis by 35 percent and significantly inhibit elastase activity to slow elastin degradation.
FIG. 4 is a photograph of in vitro test III of skin repair and reconstruction of cosmetic skin preparations of the cosmetic of the present invention;
matrix metalloprotease MMPs degrade almost all components of the extracellular matrix ECM, such as collagen and elastin in the dermis, where MMP-3 is able to activate MMP-1 and other family members; while specific inhibitors TIMPs can inhibit MMPs activity to maintain skin integrity.
The test proves that: myoglobin stock solution also inhibits MMP-1/MMP-2/MMP-3 activity, thereby maintaining dermal structural integrity.
FIG. 5 is a photograph of the skin repair and reconstruction in vivo test of the cosmetic of the present invention;
(A) test photographs of skin fibroblasts of 50-year-old volunteers; (B) test photographs were reconstructed from fibroblasts of 50-year-old volunteers after using collagen to repair the stock solution; (C) young skin.
The troponin stock solution can obviously increase the thickness of the epidermis in a skin model constructed by old fibroblasts, and the increased thickness can be compared with a model constructed by young fibroblasts.
The above description is only an embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of changes or substitutions within the technical scope of the present invention, and all such changes or substitutions are included in the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (11)
1. A cosmetic of the protocollagen of the cambogia is characterized in that: the composite material comprises the following raw materials in parts by mass: 50-55 parts of group A raw materials and 20-32 parts of collagen promotion raw materials.
2. The cosmetic of claim 1, wherein the cosmetic comprises at least one of the following components: the collagen promoting group raw material comprises a plukenetia volubilis linneo component, and the plukenetia volubilis linneo component is plukenetia volubilis linneo oil and/or plukenetia volubilis linneo oil microemulsion.
3. The cosmetic of claim 2, wherein the cosmetic comprises at least one of the following components: the collagen promoting group raw material also comprises one or more of squalane, snail secretion filtrate, coenzyme Q10, and evening primrose essential oil.
4. The cosmetic of claim 3, wherein the cosmetic comprises at least one of the following components: the collagen promoting protein group raw material comprises the following components in parts by weight: 10-13 parts of plukenetia volubilis linneo oil, 3-4.5 parts of squalane, 2-4.5 parts of snail secretion filtrate, 102.5-5 parts of coenzyme Q and 2.5-3 parts of evening primrose essential oil.
5. The cosmetic of the guayule troponin type according to any one of claims 1 to 2, characterized in that: the group A raw materials comprise the following components in parts by weight: 45-50 parts of water, 1-2 parts of corn gluten amino acids, 2-3 parts of trehalose and 3-3.5 parts of butanediol.
6. The cosmetic of claim 5, wherein the cosmetic comprises at least one of the following components: the cosmetic also comprises 3-3.8 parts of group B raw materials, wherein the group B raw materials comprise the following components in parts by weight: 2.5 to 3.5 portions of 1, 3-propylene glycol and 0.35 to 0.65 portion of polyacrylate cross-linked polymer-6.
7. The cosmetic of claim 6, wherein the cosmetic comprises at least one of the following components: the cosmetic also comprises 3.0-3.8 parts of group C raw materials, wherein the group C raw materials comprise the following components in parts by weight: 2.5-3.5 parts of 1, 3-propylene glycol and 0.35-0.65 part of p-hydroxyacetophenone.
8. The cosmetic of claim 7, wherein the cosmetic comprises at least one of the following components: the cosmetic also comprises 6.0-8.0 parts of group D raw materials, wherein the group D raw materials comprise the following components in parts by weight: 0.5-0.8 part of panthenol, 4-7 parts of glycerol glucoside, 1-1.5 parts of golden chamomile extract/mint leaf extract/pelargonium graveolens extract/purslane extract/aloe barbadensis leaf extract/sophora flavescens root extract, 1-1.5 parts of peony root extract/loquat leaf extract/selaginella tamariscina extract/cacumen biotae extract and 0.4-0.7 part of 1, 2-hexanediol.
9. The cosmetic of claim 5, wherein the cosmetic comprises at least one of the following components: the cosmetic also comprises 30-40 parts of group E raw materials, wherein the group E raw materials comprise the following components in parts by weight: 4.5-6.5 parts of chlorella deep repair factor, 5.0-8.0 parts of palmitoyl tripeptide-5 parts and 20-30 parts of hydrolyzed collagen.
10. A preparation method of cosmetic of guayule troponin stock solution is characterized in that: the method comprises the following steps:
step one, sequentially adding the group A raw materials and the collagen promotion raw material components into a batching pot, stirring and heating to 85-90 ℃ for complete dissolution, keeping the temperature for 30 minutes, and stirring at the rotating speed of 25-30 rpm;
step two, mixing and dispersing the raw materials of the group B, adding the mixture into a mixing pot, stirring and homogenizing until the mixture is completely dissolved, wherein the stirring speed is 35-38 rpm;
step three, continuously cooling and stirring the temperature of the batching pot in the step two to 55-60 ℃, adding the pre-dissolved C group raw materials and uniformly stirring, wherein the stirring speed is 20-25 rpm;
step four, cooling and stirring the temperature of the mixing pot in the step three to 38-42 ℃, adding the group D raw materials and uniformly stirring, wherein the stirring speed is 18-20 rpm;
step five, cooling and stirring the temperature of the batching pot in the step four to 35-38 ℃, adding the raw materials of the group E, and uniformly stirring at the stirring speed of 15-18rpm to finish the preparation.
11. The method for preparing cosmetic of cambogia collagen stock solution according to claim 9, wherein the method comprises the following steps: the method also comprises a pretreatment step before the first step, wherein the pretreatment step specifically comprises the following steps: thoroughly cleaning and sterilizing production equipment, and calibrating the production equipment;
and/or
A detection step is further included after the fifth step, wherein the detection step specifically refers to: stopping the machine, sampling and detecting, and filtering and discharging after the detection is qualified.
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