CN108619047A - A kind of cosmetic formulations of anti-aging and preparation method thereof - Google Patents
A kind of cosmetic formulations of anti-aging and preparation method thereof Download PDFInfo
- Publication number
- CN108619047A CN108619047A CN201810564711.XA CN201810564711A CN108619047A CN 108619047 A CN108619047 A CN 108619047A CN 201810564711 A CN201810564711 A CN 201810564711A CN 108619047 A CN108619047 A CN 108619047A
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- Prior art keywords
- component
- aging
- cosmetic formulations
- oil phase
- mass percent
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Classifications
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
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- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
Technical field of daily necessities of the present invention, specially a kind of cosmetic formulations of anti-aging and preparation method thereof are in terms of 100% by cosmetics obtained, it includes the mass percent of each component be：Oil phase component is 12.7 17.5%；Water phase components are 86.04 76.19%；Triethanolamine is 0.15 0.2%；Anti-ageing group is divided into 4.11 9.11%.Inventive formulation is economical and practical with senile-resistant efficacy, is formulated reasonable benefit/risk, not will produce adverse reaction；The preparation method preparation process of the cosmetics of offer is simple.
Description
Technical field
The present invention relates to technical field of daily necessities, and in particular to a kind of cosmetic formulations of anti-aging and preparation method thereof.
Background technology
The anti-aging of skin refers to that gradual function and organic degeneration occur because of the passage of time for delaying skin
Variation shows as preventing that wrinkle, drying, bits, coarse, loose and color spot, anti-aging cosmetics are exactly to realize anti-aging
The cosmetics of effect, are important one of effect cosmetic.
Skin aging is a kind of natural phenomena, but we live in have several factors all and can accelerate the process of aging, now lead to
It crosses anti-aging product and slows down this phenomenon.
The anti-aging mechanism of skin can set about from the several directions being set forth below：
1. during free-radical oxidation reaction generates aliphatic acid, by free radical scavenger, preventing reaction from carrying out, preventing into one
Step reaction forms pigment.
2. by the protection to skin, cell generates free radicals caused by preventing extraneous pollution, by adding antioxygen
Chemical conversion point, prevents intracellular free radical from generating, and by adding active ingredient, captures established free radical.
3. preventing UV radiation injury fibrocytes, causes collagen and elastic collagen to reduce, prevent UV radiation from luring
Mitochondrial DNA damage, causes ROS（Active chalcogen）It is excessive, cause free radical to increase.
In summary three kinds of directions come inquire into realize skin anti-aging approach, anti-aging be mainly the following approach and
The mentality of designing of measure namely this formula：Skin Cell is protected to be stimulated from external environment, as prevented UV from radiating to skin
Sun-proof raw material progress preventing coating protection is added in injury in formula system, such as ethylhexyl salicylate, methoxy cinnamic acid ethyl hexyl
Ester etc.；Extra free radical in scavenger-cell removes radical type raw material, such as oat extract, tocopherol；It is thin to skin
Born of the same parents repair, and supplement the nutrients such as ubiquinone, protein hydrolysate, peptide tire out raw material.
The action principle of cosmetics anti-aging product is that the balance of regeneration and the degeneration of skin is made to reach a kind of normal shape
State increases the synthesis of collagen and elastin laminin.Common raw material avocado oil, the derivative of vitamin A and α-hydroxycarboxylic acid etc.
Avocado oil：Containing minerals such as abundant vitamin A, B1, B2 and D potassium, phosphorus, magnesium, sulphur, calcium, sodium, copper, it is easy by deep layer group
Knit absorption, can effectively softening skin tissue, skin moisturization is apparent, can alleviate eczema and psoriasic symptom, so
It is particularly suitable for the use of aging skin.But know from relevant report, through remarkable and animal skin and Eye testing, avocado oil
There is microstimulation reaction, but simultaneously no evidence shows and can cause allergy.But also there is report to point out, leaf, fruit, the bark of avocado
Can occur poisoning phenomenon to ox, horse, sheep, rabbit and canary with seed.The derivative of vitamin A：It can be absorbed by skin,
Skin epidermal cells are made to activate.The synthesis for changing and adjusting glue fat helps to maintain skin emolliency and plentiful, improves the screen of skin
Hinder function.But its is unstable, light, decomposes and changes colour after heat, is also unfavorable for the application in product.α-hydroxycarboxylic acid：Main packet
Containing lactic acid, tartaric acid, citric acid, salicylic acid etc., they can increase the generation of colloidal sol protoenzyme, there is special work(to dry cracked skin
Effect, the aging of energy delaying skin, but have certain requirement to concentration and frequency of use in cosmetics, it cannot be used for a long time
Either it is excessively used.Otherwise to skin, there are certain destructions.
Invention content
In order to overcome the deficiencies of existing technologies, technical problem to be solved by the present invention lies in propose a kind of change of anti-aging
Cosmetic formula.
Another technical problem of proposition to be solved of the present invention is to provide the preparation method of the cosmetic formulations.
For this purpose, the present invention uses following technical scheme：A kind of cosmetic formulations of anti-aging provided by the invention,
Be in terms of 100% by cosmetics obtained, it includes the mass percent of each component be：
Oil phase component 12.7~17.5%；
Water phase components 86.04~76.19%；
Triethanolamine 0.15-0.2%；
Anti-ageing component 4.11-9.11%.
Preferably, the mass percent of each component of the water phase components is：
Carbomer 0.15-0.20%；
Glycerine 3.0-5.0%；
Butanediol 2.0-4.0%；
Allantoin 0.05-0.2%；
Hyaluronic acid 0.05-0.1%；
Methyl esters 0.2%；
Deionized water adds to 103%.
Preferably, the mass percent of each component of the oil phase component is：
- 6 1.0-1.5% of ceteth；
- 25 1.5-2.0% of ceteth；
Parleam 3.0-4.0%；
Caprylic/capric triglyceride 3.5-5.0%；
Dimethyl silicone polymer 1.5-2.0%；
Cetostearyl alcohol 0.5-1.0%；
Tocopherol acetate 0.3-1.0%；
Butylmethoxydibenzoylmethane 0.3-0.5%；
4 methyl benzylidene camphor 0.3--0.5%；
Octocrilene 0.3--0.5%.
Preferably, the mass percent of each component of the anti-ageing component is：
Azone/Cremophor RH40 0.1-0.5%；
Felwort extracting solution 0.5-1.0%；
Oat extract 0.5-3%；
Avenabeta glucosan 0.5-0.8%；
Ubiquinone 0.5-1.0%；
Dent looks for extract 0,5-1.0%；
- 5 0.3-1.5% of palmityl tripeptides；
Protein hydrolysate 0.1-0.5%；
Phenoxyethanol 0.5%；
Glycerol caprylate 0.O4%；
Essence 0.07%.
Preferably, a kind of preparation method of the cosmetic formulations of anti-aging is used for the cosmetic formulations of the anti-aging
Preparation, implement as follows：
（1）After oil phase component has been weighed, oil phase pot is added, it is complete that stirring is warming up to 75-85 DEG C of dissolving；
（2）After water phase components have been weighed, addition emulsification pot is warming up to 80-85 DEG C and keeps the temperature 20 minutes；
（3）After be pumped into oil phase component, homogeneous 5-10min is added triethanolamine insulated and stirred 5-10min, vacuumizes cooling；
（4）40 DEG C or so are added anti-ageing component, stir evenly to get anti-aging cosmetics.
Beneficial effects of the present invention：The cosmetic formulations of a kind of anti-aging provided by the invention, with senile-resistant efficacy
It is again economical and practical；The preparation process of the cosmetic formulations of the anti-aging of offer is simple, of low cost.
Specific implementation mode
The technical solution further illustrated the present invention below by specific implementation mode.Obviously, described embodiment
Only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, the common skill in this field
All other embodiment that art personnel are obtained without creative efforts belongs to the model that the present invention protects
It encloses.
Embodiment 1
Be in terms of 100% by cosmetics obtained, it includes the mass percent of each component be：
Oil phase component 12.7%；
Water phase components 86.04%；
Triethanolamine 0.15%；
Anti-ageing component 4.11%.
The mass percent of each component of oil phase component is：
Ceteth -6 1.0%；
Ceteth -25 1.5%；
Parleam 3.0%；
Caprylic/capric triglyceride 3.5%；
Dimethyl silicone polymer 1.5%；
Cetostearyl alcohol 1.0%；
Tocopherol acetate 0.3%；
Butylmethoxydibenzoylmethane 0.3%；
4 methyl benzylidene camphor 0.3%；
Octocrilene 0.3%.
The mass percent of each component of water phase components is：
Carbomer 0.15%；
Glycerine 3.0%；
Butanediol 2.0%；
Allantoin 0.05%；
Hyaluronic acid 0.05%；
Methyl esters 0.2%；
Deionized water adds to 103%.
The mass percent of each component of anti-ageing component is：
Azone/Cremophor RH40 0.1%；
Felwort extracting solution 0.5%；
Oat extract 0.5%；
Avenabeta glucosan 0.5%；
Ubiquinone 0.5%；
Dent looks for extract 0.5%；
Palmityl tripeptides -5 0.3%；
Protein hydrolysate 0.1%；
Phenoxyethanol 0.5%；
Glycerol caprylate 0.O4%；
Essence 0.07%.
Adjuvant component includes one or both of 1% essence, adjusting pH value, viscosity.
A kind of cosmetic formulations preparation method of anti-aging, the preparation of the cosmetics for anti-aging are real as follows
It applies：
（1）Oil phase pot is added after oil phase component has been weighed, stirring is warming up to 75-80 DEG C to being completely dissolved；
（2）Emulsification pot is added after water phase components have been weighed, stirring is warming up to 80-85 DEG C and keeps the temperature 20 minutes；Stirring is lower to be pumped into oil
Phase component, homogeneous 5-10min, insulated and stirred 5-10min vacuumize cooling；
（3）Temperature drops to 70 DEG C of addition triethanolamines and continues to stir evenly
（4）Temperature drops to 40 DEG C or so and anti-ageing component is added, and stirs evenly to get product of the present invention.
Embodiment 2
Be in terms of 100% by cosmetics obtained, it includes the mass percent of each component be：
Oil phase component 17.5%；
Water phase components 75.39%；
Triethanolamine 0.2%；
Anti-ageing component 9.11%.
The mass percent of each component of oil phase component is：
Ceteth -6 1.5%；
Ceteth -25 2.0%；
Parleam 4.0%；
Caprylic/capric triglyceride 5.0%；
Dimethyl silicone polymer 2.0%；
Cetostearyl alcohol 0.5%；
Tocopherol acetate 1.0%；
Butylmethoxydibenzoylmethane 0.5%；
4 methyl benzylidene camphor 0.5%；
Octocrilene 0.5%.
The mass percent of each component of water phase components is：
Carbomer 0.20%；
Glycerine 5.0%；
Butanediol 4.0%；
Allantoin 0.2%；
Hyaluronic acid 0.8%；
Methyl esters 0.2%；
Deionized water adds to 103%.
The mass percent of each component of anti-ageing component is：
Azone/Cremophor RH40 0.5%；
Felwort extracting solution 1.0%；
Oat extract 3%；
Avenabeta glucosan 0.8%；
Ubiquinone 1.0%；
Dent looks for extract 1.0%；
Palmityl tripeptides -5 1.5%；
Protein hydrolysate 0.5%；
Phenoxyethanol 0.5%；
Glycerol caprylate 0.O4%；
Essence 0.07%.
A kind of cosmetic formulations preparation method of anti-aging, the preparation of the cosmetics for anti-aging are real as follows
It applies：
（1）Oil phase pot is added after oil phase component has been weighed, stirring is warming up to 75-80 DEG C to being completely dissolved；
（2）Emulsification pot is added after water phase components have been weighed, stirring is warming up to 80-85 DEG C and keeps the temperature 20 minutes；Stirring is lower to be pumped into oil
Phase component, homogeneous 5-10min, insulated and stirred 5-10min vacuumize cooling；
（3）Temperature drops to 70 DEG C of addition triethanolamines and continues to stir evenly
（4）Temperature drops to 40 DEG C or so and anti-ageing component is added, and stirs evenly to get product of the present invention.
Testing performance index
（1）Appearance：White has mobility exquisiteness lotion；
（2）Odor type：Essence；
（3）Viscosity：10000-20000mpa.s（25 DEG C, 3#, 6r/min）
（4）Cold-resistant study on the stability（48℃X24h）：It is qualified；
（5）Cold-resistant study on the stability（-15℃X24h）：It is qualified；
Skin irritation test
Each 20 of men and women between choosing 20 ~ 40 years old, everyone smears 0.5g this products, range after its inboard arm, ear at root
It is 2cmX2cm, twice daily, observes and records the dermoreaction for 24 hours, after 72h.
The result shows that：Applying product of the present invention, skin has no that the local stimulations such as rubescent, dermexanthesis, water lump are reacted for 24 hours, after 72h, says
Bright sun care preparations of the present invention is safety, is had no adverse reaction.
Product Curative effect
The effect of product of the present invention, counts：Volunteer 500, man 170, female 330, age reckling 20 years old, the maximum 40
Year, average age 31.12 years old.Each subject uses anti-aging cosmetics of the present invention, is sung after cleaning skin in daily morning
It chants .5g or so and is uniformly applied to face or arm, be used continuously 1 month（One course for the treatment of）.
Effect criterion
It is excellent：Feel comfortable, dim skin obviously restore natural elasticity, compact, wrinkle quantity, roughness significantly reduce；
It is good：Feel that general, skin surface roughness, relaxation symptom are no longer deepened；
Difference：Do not changed using front and back skin.
As a result：In 500, effect judges the superior 111, accounts for 22.2%；Effect judges good person 389, accounts for 77.8%；In total
Effective percentage is 10%.Whole subjects are without 1 presentation adverse reaction.
Finally, it should be noted that present invention disclosed above preferred embodiment is only intended to help to illustrate the present invention.It is excellent
It selects embodiment there is no all details of detailed descriptionthe, does not limit the invention to the specific embodiments described.Obviously, root
According to the content of this specification, can make many modifications and variations.These embodiments are chosen and specifically described to this specification, be in order to
The principle of the present invention and practical application are preferably explained, to enable skilled artisan to be best understood by and utilize
The present invention.The invention is limited only by the claims and the full scope thereof and equivalents thereof.
Claims (5)
1. a kind of cosmetic formulations of anti-aging, it is characterised in that：By cosmetics obtained be 100% in terms of, it includes each component
Mass percent be：
Oil phase component 12.7~17.5%；
Water phase components 86.04~76.19%；
Triethanolamine 0.15-0.2%；
Anti-ageing component 4.11-9.11%.
2. cosmetic formulations as described in claim 1, it is characterised in that：The mass percent of each component of the water phase components
For：
Carbomer 0.15-0.20%；
Glycerine 3.0-5.0%；
Butanediol 2.0-4.0%；
Allantoin 0.05-0.2%；
Hyaluronic acid 0.05-0.1%；
Methyl esters 0.2%；
Deionized water adds to 103%.
3. cosmetic formulations as described in claim 1, it is characterised in that：The mass percent of each component of the oil phase component
For：
- 6 1.0-1.5% of ceteth；
- 25 1.5-2.0% of ceteth；
Parleam 3.0-4.0%；
Caprylic/capric triglyceride 3.5-5.0%；
Dimethyl silicone polymer 1.5-2.0%；
Cetostearyl alcohol 0.5-1.0%；
Tocopherol acetate 0.3-1.0%；
Butylmethoxydibenzoylmethane 0.3-0.5%；
4 methyl benzylidene camphor 0.3--0.5%；
Octocrilene 0.3--0.5%.
4. cosmetic formulations as described in claim 1, it is characterised in that：The mass percent of each component of the anti-ageing component
For：
Azone/Cremophor RH40 0.1-0.5%；
Felwort extracting solution 0.5-1.0%；
Oat extract 0.5-3%；
Avenabeta glucosan 0.5-0.8%；
Ubiquinone 0.5-1.0%；
Dent looks for extract 0,5-1.0%；
- 5 0.3-1.5% of palmityl tripeptides；
Protein hydrolysate 0.1-0.5%；
Phenoxyethanol 0.5%；
Glycerol caprylate 0.O4%；
Essence 0.07%.
5. a kind of preparation method of the cosmetic formulations of anti-aging, the cosmetics for the addition ginger described in Claims 1-4
Preparation, which is characterized in that implement as follows：
（1）After oil phase component has been weighed, oil phase pot is added, it is complete that stirring is warming up to 75-85 DEG C of dissolving；
（2）After water phase components have been weighed, addition emulsification pot is warming up to 80-85 DEG C and keeps the temperature 20 minutes；
（3）After be pumped into oil phase component, homogeneous 5-10min is added triethanolamine insulated and stirred 5-10min, vacuumizes cooling；
（4）40 DEG C or so are added anti-ageing component, stir evenly to get anti-aging cosmetics.
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| WO2023230955A1 (en) * | 2022-06-01 | 2023-12-07 | Nivea (Shanghai) Co. Ltd. | Silicone-free emulsion i |
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