CN108815093A - A kind of pore shrinks Essence and preparation method thereof - Google Patents
A kind of pore shrinks Essence and preparation method thereof Download PDFInfo
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- CN108815093A CN108815093A CN201810710183.4A CN201810710183A CN108815093A CN 108815093 A CN108815093 A CN 108815093A CN 201810710183 A CN201810710183 A CN 201810710183A CN 108815093 A CN108815093 A CN 108815093A
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- Prior art keywords
- parts
- essence
- wrack
- tip edge
- shrinks
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- 239000011148 porous material Substances 0.000 title claims abstract description 26
- 238000002360 preparation method Methods 0.000 title claims abstract description 18
- 239000000284 extract Substances 0.000 claims abstract description 42
- 241000227647 Fucus vesiculosus Species 0.000 claims abstract description 23
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 21
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims abstract description 18
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 claims abstract description 13
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims abstract description 13
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 claims abstract description 13
- 150000008442 polyphenolic compounds Chemical class 0.000 claims abstract description 12
- 235000013824 polyphenols Nutrition 0.000 claims abstract description 12
- 241000241413 Propolis Species 0.000 claims abstract description 11
- 235000009508 confectionery Nutrition 0.000 claims abstract description 11
- 229940069949 propolis Drugs 0.000 claims abstract description 11
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims abstract description 9
- 229910021529 ammonia Inorganic materials 0.000 claims abstract description 9
- 102000004400 Aminopeptidases Human genes 0.000 claims abstract description 7
- 108090000915 Aminopeptidases Proteins 0.000 claims abstract description 7
- 102000015636 Oligopeptides Human genes 0.000 claims abstract description 7
- 108010038807 Oligopeptides Proteins 0.000 claims abstract description 7
- 108091005804 Peptidases Proteins 0.000 claims abstract description 7
- 239000004365 Protease Substances 0.000 claims abstract description 7
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims abstract description 7
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims abstract description 7
- 229920001184 polypeptide Polymers 0.000 claims abstract description 7
- 102000004196 processed proteins & peptides Human genes 0.000 claims abstract description 7
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 7
- 239000003643 water by type Substances 0.000 claims abstract description 7
- 229920002125 Sokalan® Polymers 0.000 claims abstract description 6
- 235000019437 butane-1,3-diol Nutrition 0.000 claims abstract description 6
- GHBFNMLVSPCDGN-UHFFFAOYSA-N rac-1-monooctanoylglycerol Chemical class CCCCCCCC(=O)OCC(O)CO GHBFNMLVSPCDGN-UHFFFAOYSA-N 0.000 claims abstract description 6
- 241001252601 Blumea Species 0.000 claims abstract description 5
- 229920002385 Sodium hyaluronate Polymers 0.000 claims abstract description 5
- 239000003921 oil Substances 0.000 claims abstract description 5
- 239000000126 substance Substances 0.000 claims abstract description 5
- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical class COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 claims abstract description 4
- 239000008389 polyethoxylated castor oil Substances 0.000 claims abstract description 4
- 239000002994 raw material Substances 0.000 claims abstract description 4
- 244000269722 Thea sinensis Species 0.000 claims abstract 6
- 239000000843 powder Substances 0.000 claims description 20
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 18
- 238000003756 stirring Methods 0.000 claims description 18
- 238000000034 method Methods 0.000 claims description 14
- 241000202807 Glycyrrhiza Species 0.000 claims description 12
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 12
- 229940010454 licorice Drugs 0.000 claims description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 239000006228 supernatant Substances 0.000 claims description 11
- 239000003292 glue Substances 0.000 claims description 10
- 238000007873 sieving Methods 0.000 claims description 10
- 229940118127 fucus vesiculosus extract Drugs 0.000 claims description 7
- 239000007788 liquid Substances 0.000 claims description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims description 6
- CBTVGIZVANVGBH-UHFFFAOYSA-N aminomethyl propanol Chemical compound CC(C)(N)CO CBTVGIZVANVGBH-UHFFFAOYSA-N 0.000 claims description 6
- 239000007864 aqueous solution Substances 0.000 claims description 6
- 239000008367 deionised water Substances 0.000 claims description 6
- 229910021641 deionized water Inorganic materials 0.000 claims description 6
- 238000007598 dipping method Methods 0.000 claims description 6
- 239000000706 filtrate Substances 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 6
- 238000002156 mixing Methods 0.000 claims description 6
- 239000013049 sediment Substances 0.000 claims description 6
- 235000007866 Chamaemelum nobile Nutrition 0.000 claims description 5
- 244000042664 Matricaria chamomilla Species 0.000 claims description 5
- 235000007232 Matricaria chamomilla Nutrition 0.000 claims description 5
- 238000001035 drying Methods 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 claims description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 3
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims description 3
- 108010059892 Cellulase Proteins 0.000 claims description 3
- 102000004190 Enzymes Human genes 0.000 claims description 3
- 108090000790 Enzymes Proteins 0.000 claims description 3
- 229920002690 Polyoxyl 40 HydrogenatedCastorOil Polymers 0.000 claims description 3
- 229960000458 allantoin Drugs 0.000 claims description 3
- 229960001631 carbomer Drugs 0.000 claims description 3
- 229940106157 cellulase Drugs 0.000 claims description 3
- 238000005119 centrifugation Methods 0.000 claims description 3
- 230000001804 emulsifying effect Effects 0.000 claims description 3
- 238000005516 engineering process Methods 0.000 claims description 3
- 229940088598 enzyme Drugs 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 239000012528 membrane Substances 0.000 claims description 3
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 150000003904 phospholipids Chemical class 0.000 claims description 3
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 3
- 241000195493 Cryptophyta Species 0.000 claims description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 2
- 229940119217 chamomile extract Drugs 0.000 claims 1
- 235000020221 chamomile extract Nutrition 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 235000019441 ethanol Nutrition 0.000 claims 1
- 239000004744 fabric Substances 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- 229940010747 sodium hyaluronate Drugs 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 10
- 239000004615 ingredient Substances 0.000 abstract description 4
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 abstract description 3
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 3
- 229940009662 edetate Drugs 0.000 abstract description 3
- 235000015424 sodium Nutrition 0.000 abstract description 3
- 230000003255 anti-acne Effects 0.000 abstract description 2
- -1 anti-acne Substances 0.000 abstract description 2
- 239000002260 anti-inflammatory agent Substances 0.000 abstract description 2
- 230000001741 anti-phlogistic effect Effects 0.000 abstract description 2
- 235000021122 unsaturated fatty acids Nutrition 0.000 abstract description 2
- 150000004670 unsaturated fatty acids Chemical class 0.000 abstract description 2
- KODLUXHSIZOKTG-UHFFFAOYSA-N 1-aminobutan-2-ol Chemical class CCC(O)CN KODLUXHSIZOKTG-UHFFFAOYSA-N 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 16
- 241001122767 Theaceae Species 0.000 description 11
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 4
- 238000000227 grinding Methods 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 208000002874 Acne Vulgaris Diseases 0.000 description 2
- 241000700647 Variola virus Species 0.000 description 2
- 206010000496 acne Diseases 0.000 description 2
- 238000007605 air drying Methods 0.000 description 2
- OBETXYAYXDNJHR-UHFFFAOYSA-N alpha-ethylcaproic acid Natural products CCCCC(CC)C(O)=O OBETXYAYXDNJHR-UHFFFAOYSA-N 0.000 description 2
- 230000008602 contraction Effects 0.000 description 2
- 230000008014 freezing Effects 0.000 description 2
- 238000007710 freezing Methods 0.000 description 2
- 125000005456 glyceride group Chemical group 0.000 description 2
- 235000019198 oils Nutrition 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000008159 sesame oil Substances 0.000 description 2
- 235000011803 sesame oil Nutrition 0.000 description 2
- 238000009736 wetting Methods 0.000 description 2
- 230000002407 ATP formation Effects 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010039792 Seborrhoea Diseases 0.000 description 1
- 102000003425 Tyrosinase Human genes 0.000 description 1
- 108060008724 Tyrosinase Proteins 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 210000002752 melanocyte Anatomy 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 210000003470 mitochondria Anatomy 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000037312 oily skin Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000037307 sensitive skin Effects 0.000 description 1
- 210000004927 skin cell Anatomy 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9711—Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
Abstract
A kind of pore shrinks Essence and preparation method thereof, belongs to Essence preparation technical field, the raw material including following parts by weight:2-4 parts of tea polyphenol extract objects, 2-4 parts of propolis extracts, 1-3 parts of double sweet ammonia skins, 0.5-1 parts of protease, 0.5-1 parts of aminopeptidases, 1-2 parts of camomile extracts, 1-2 parts of licorices, 1-3 parts of yeast polypeptides, 2-4 parts of tip edge bladder-wrack extracts, 1-3 parts of oligopeptides -20, 0.5-1 parts of carbomers, 0.6-2 parts of aminomethyl propanols, 3-6 parts of propylene glycol, 3-6 part 1, 3- butanediol, 0.5-1 parts of Cremophor RH40s, 0.5-1 parts of blumea oils, 0.5-1 parts of glycerol caprylates, 0.1-0.2 parts of methyl hydroxybenzoates, 0.1-0.2 parts of allantoins, 0.02-0.1 parts of EDETATE SODIUMs, 0.03-0.1 parts of Sodium Hyaluronates, 70-100 parts of deionized waters.Double sweet ammonia skins, which contain, inhibits the dysgenic ingredient of unsaturated fatty acid, can not only reduce the structure that pore expands outwardly, while can also improve the skin condition around pore.The effect of tea polyphenols are water-soluble substances, have and remove the greasy of face, convergence pore, anti-acne, antiphlogistic and bactericidal.
Description
Technical field
The present invention relates to Essence preparation technical field, in particular to a kind of pore shrinks Essence and preparation method thereof.
Background technique
Essence is the superfine product in skin care item, and ingredient is exquisite, effect is powerful, significant effect, remains what it possessed
It is noble and mysterious, it is suitable for any skin or inclined oily skin, preferably puts in the vial, take at any time.Essence is used for toner
Later, before face cream.Commonly there is poor permeability, be not easy the problems such as absorbing, single effect in current Essence.
Summary of the invention
It is an object of the invention to overcome the deficiencies of the prior art and provide a kind of pores to shrink Essence and its preparation side
The effect of method has good penetrability, easily absorbs, pore refining.
The present invention uses following technical scheme:
A kind of pore contraction Essence, the raw material including following parts by weight:2-4 parts of tea polyphenol extract objects, 2-4 parts of propolis
Extract, 1-3 parts of double sweet ammonia skins, 0.5-1 parts of protease, 0.5-1 parts of aminopeptidases, 1-2 parts of camomile extracts, 1-2 parts it is sweet
Careless extract, 1-3 part yeast polypeptides, 2-4 parts of tip edge bladder-wrack extracts, 1-3 parts of oligopeptides -20,0.5-1 parts of carbomers, 0.6-2
Part aminomethyl propanol, 3-6 parts of propylene glycol, 3-6 parts of 1,3 butylene glycols, 0.5-1 parts of Cremophor RH40s, 0.5-1 parts of Ai Na
Sesame oil, 0.5-1 part glycerol caprylate, 0.1-0.2 parts of methyl hydroxybenzoates, 0.1-0.2 parts of allantoins, 0.02-0.1 parts of EDETATE SODIUMs,
0.03-0.1 parts of Sodium Hyaluronates, 70-100 parts of deionized waters.
A kind of pore shrinks the preparation method of Essence, includes the following steps:
Step 1:It takes tealeaves to crush, crosses 80 meshes, obtain tea powder, accurately weighed tea powder 4g, with 120mL volumetric concentration 25%
Ethanol solution wetting, is added by cellulase and pectase in mass ratio 1:The complex enzyme 6mg of 1 composition, is placed in 50 DEG C of thermostatted waters
Completely cut off air stirring 30min in bath, extracted under conditions of 50 DEG C, microwave power 400W, gained extract liquor is diluted 5 times and quiet
10min is set, supernatant liquor is drawn, both obtains tea polyphenol extract object;
Step 2:It weighs in deionized water to water phase pot, sequentially adds the measured EDETATE SODIUM of accurate scale, hyaluronic acid
Sodium, carbomer, and heating mixes while stirring, is sufficiently stirred and is uniformly dissolved under temperature 60 C, sequentially adds propylene glycol, 1,3-
Butanediol, methyl hydroxybenzoate, allantoin, temperature 60 C keep the temperature 30 minutes;
Step 3:In temperature 60 C, material in water phase pot is pumped into vacuum emulsifying pot, under stirring successively
Be added tea polyphenol extract object, propolis extract, protease, aminopeptidase, camomile extract, licorice, double sweet ammonia skins,
Yeast polypeptides, tip edge bladder-wrack extract, oligopeptides -20 stir 30 minutes, are sufficiently mixed uniformly;
Step 4:It cools, when temperature drops to 45 DEG C, Cremophor RH40, blumea oil, octanoic acid is added
Glyceride, and stir;
Step 5:Continue to cool down, when temperature drops to 35 DEG C, aminomethyl propanol is added, and stir, then cold
But to room temperature to get Essence.
Preferably, the propolis extract is nanometer supercritical bee-glue.
It is further preferred that the nanometer supercritical bee-glue is the nanometer being process by Phospholipids nano-encapsulated technology
Supercritical bee-glue.
Preferably, the licorice is prepared using following methods:5g licorice medicinal materials are crushed, sieving, obtains powder
The NaOH aqueous solution that concentration is 0.2mol/L is added in body, is 1 by solid-to-liquid ratio:The mixing of 10 ratios, 2h is extracted in hot dipping at 80 DEG C,
It is repeated 2 times, filters, it is 3% hydrochloric acid tune pH value to 1-2.5 that mass concentration is added in filtrate, is centrifuged under the revolving speed of 4000r/min
Separation, goes supernatant to obtain sediment, as licorice.
Preferably, the camomile extract is prepared using following methods:5g chamomile is crushed, sieving, obtains powder
The NaOH aqueous solution that concentration is 0.2mol/L is added in body, is 1 by solid-to-liquid ratio:The mixing of 10 ratios, 2h is extracted in hot dipping at 80 DEG C,
It is repeated 2 times, filters, it is 3% hydrochloric acid tune pH value to 1-2.5 that mass concentration is added in filtrate, is centrifuged under the revolving speed of 4000r/min
Separation, goes supernatant to obtain sediment, as camomile extract.
Preferably, the tip edge bladder-wrack extract is prepared using following methods:Tip edge bladder-wrack is washed, is put
It sets and is carried out at aeration-drying air-dried, the tip edge bladder-wrack after air-drying is placed in micro-wave oven, the dry 4min of moderate heat, after drying
Tip edge bladder-wrack be put into pulverizer and crush, smashed tip edge bladder-wrack is crossed into 60 meshes, tip edge bladder-wrack powder is obtained, weighs
Tip edge bladder-wrack powder 10g, deionized water 100g, are added to the container, and decoct at 90 DEG C and extract 100min, by the substance in container
It all takes out, is cooled to room temperature, filtered with cryogenic freezing centrifuge, revolving speed 3000r/min, centrifugation time 5min, in collection
Clear liquid obtains tip edge bladder-wrack extract after filtering.
It is further preferred that described is filtered into three layers of filtered through gauze.
It is further preferred that being filtered after three layers of filtered through gauze using the membrane filter in 0.2 μm of aperture.
Preferably, the grinding and sieving was 40 meshes.
The beneficial effects of the present invention are:
1) double sweet ammonia skins, which contain, inhibits the dysgenic ingredient of unsaturated fatty acid, can not only reduce what pore expanded outwardly
Structure, while the skin condition around pore can also be improved.
2) the effect of tea polyphenols are water-soluble substances, have and remove the greasy of face, convergence pore, anti-acne, antiphlogistic and bactericidal,
It can also stop ultraviolet light and remove the free radical of ultraviolet induction, to protect the normal function of melanocyte, inhibit black
The formation of pigment, while inhibition is generated to lipid oxidation, mitigate pigmentation.
3) the effect of Radix Glycyrrhizae has clearing heat and detoxicating, antibacterial anti-inflammatory.It is especially suitable for the skin for having small pox, frequent inflammation, has
Calmness is pacified, facial acne is eliminated, and effectively prevents the generation of small pox acne, is suitble to various skin, is particularly suitable for sensibility flesh
Skin.
4) chamomile have disinfecting, antimicrobial, releive sensitive skin the effect of.
5) present invention uses nanometer supercritical bee-glue, it is easy to which infiltration and absorption successfully solve and other ingredients
Compatibility issues, nanometer supercritical bee-glue have the function of that strength is anti-oxidant, inhibit tyrosinase activity, and whitening spot-removing effect is aobvious
It writes.
6) required natural nutrient needed for tip edge bladder-wrack can provide skin rapid regeneration and cell normal growth, Replacement Battalion
Feeding loss promotes skin metabolism, increases skin energy element ATP synthesis;It protects skin cell mitochondria and maintains line grain
Body function;Promote skin revitalization, skin is helped to reply health and vigor.
Specific embodiment
With reference to embodiments, the technical solution in the present invention is clearly and completely described.Based in the present invention
Embodiment, every other embodiment obtained by those of ordinary skill in the art without making creative efforts, all
Belong to the scope of protection of the invention.
A kind of pore contraction Essence, the raw material including following parts by weight:2-4 parts of tea polyphenol extract objects, 2-4 parts of propolis
Extract, 1-3 parts of double sweet ammonia skins, 0.5-1 parts of protease, 0.5-1 parts of aminopeptidases, 1-2 parts of camomile extracts, 1-2 parts it is sweet
Careless extract, 1-3 part yeast polypeptides, 2-4 parts of tip edge bladder-wrack extracts, 1-3 parts of oligopeptides -20,0.5-1 parts of carbomers, 0.6-2
Part aminomethyl propanol, 3-6 parts of propylene glycol, 3-6 parts of 1,3 butylene glycols, 0.5-1 parts of Cremophor RH40s, 0.5-1 parts of Ai Na
Sesame oil, 0.5-1 part glycerol caprylate, 0.1-0.2 parts of methyl hydroxybenzoates, 0.1-0.2 parts of allantoins, 0.02-0.1 parts of EDETATE SODIUMs,
0.03-0.1 parts of Sodium Hyaluronates, 70-100 parts of deionized waters.
A kind of pore shrinks the preparation method of Essence, includes the following steps:
Step 1:It takes tealeaves to crush, crosses 80 meshes, obtain tea powder, accurately weighed tea powder 4g, with 120mL volumetric concentration 25%
Ethanol solution wetting, is added by cellulase and pectase in mass ratio 1:The complex enzyme 6mg of 1 composition, is placed in 50 DEG C of thermostatted waters
Completely cut off air stirring 30min in bath, extracted under conditions of 50 DEG C, microwave power 400W, gained extract liquor is diluted 5 times and quiet
10min is set, supernatant liquor is drawn, both obtains tea polyphenol extract object;
Step 2:It weighs in deionized water to water phase pot, sequentially adds the measured EDETATE SODIUM of accurate scale, hyaluronic acid
Sodium, carbomer, and heating mixes while stirring, is sufficiently stirred and is uniformly dissolved under temperature 60 C, sequentially adds propylene glycol, 1,3-
Butanediol, methyl hydroxybenzoate, allantoin, temperature 60 C keep the temperature 30 minutes;
Step 3:In temperature 60 C, material in water phase pot is pumped into vacuum emulsifying pot, under stirring successively
Be added tea polyphenol extract object, propolis extract, protease, aminopeptidase, camomile extract, licorice, double sweet ammonia skins,
Yeast polypeptides, tip edge bladder-wrack extract, oligopeptides -20 stir 30 minutes, are sufficiently mixed uniformly;
Step 4:It cools, when temperature drops to 45 DEG C, Cremophor RH40, blumea oil, octanoic acid is added
Glyceride, and stir;
Step 5:Continue to cool down, when temperature drops to 35 DEG C, aminomethyl propanol is added, and stir, then cold
But to room temperature to get Essence.
The propolis extract is nanometer supercritical bee-glue.The nanometer supercritical bee-glue is wrapped by Phospholipids nanometer
The nanometer supercritical bee-glue that the technology of wrapping up in is process.
The licorice is prepared using following methods:5g licorice medicinal materials are crushed, sieving, obtain powder, is added
Concentration is the NaOH aqueous solution of 0.2mol/L, is 1 by solid-to-liquid ratio:The mixing of 10 ratios, 2h is extracted in hot dipping at 80 DEG C, is repeated 2 times,
It filters, it is 3% hydrochloric acid tune pH value to 1-2.5 that mass concentration is added in filtrate, is centrifugated, goes under the revolving speed of 4000r/min
Supernatant obtains sediment, as licorice.
The grinding and sieving was 40 meshes.
The camomile extract is prepared using following methods:5g chamomile is crushed, sieving, obtain powder, is added
Concentration is the NaOH aqueous solution of 0.2mol/L, is 1 by solid-to-liquid ratio:The mixing of 10 ratios, 2h is extracted in hot dipping at 80 DEG C, is repeated 2 times,
It filters, it is 3% hydrochloric acid tune pH value to 1-2.5 that mass concentration is added in filtrate, is centrifugated, goes under the revolving speed of 4000r/min
Supernatant obtains sediment, as camomile extract.
The grinding and sieving was 40 meshes.
The tip edge bladder-wrack extract is prepared using following methods:Tip edge bladder-wrack is washed, is placed on logical
It air-dries dry place and carries out air-dried, the tip edge bladder-wrack after air-drying is placed in micro-wave oven, the dry 4min of moderate heat, by the tip edge after drying
Bladder-wrack is put into pulverizer and crushes, and smashed tip edge bladder-wrack is crossed 60 meshes, obtains tip edge bladder-wrack powder, weighs tip edge ink
Angle algae powder 10g, deionized water 100g, are added to the container, and decoct at 90 DEG C and extract 100min, the substance in container is all taken
Out, it is cooled to room temperature, is filtered with cryogenic freezing centrifuge, revolving speed 3000r/min, centrifugation time 5min, supernatant, mistake are collected
After filter tip edge bladder-wrack extract, it is described to be filtered into three layers of filtered through gauze, using 0.2 after three layers of filtered through gauze
The membrane filter filtering in μm aperture.
The present invention is exemplarily described above, it is clear that present invention specific implementation is not subject to the restrictions described above,
As long as using the improvement for the various unsubstantialities that the inventive concept and technical scheme of the present invention carry out, or not improved this is sent out
Bright conception and technical scheme directly apply to other occasions, within the scope of the present invention.Protection of the invention
Range should be determined by the scope of protection defined in the claims.
Claims (10)
1. a kind of pore shrinks Essence, which is characterized in that the raw material including following parts by weight:2-4 parts of tea polyphenol extract objects,
2-4 parts of propolis extracts, 1-3 parts of double sweet ammonia skins, 0.5-1 parts of protease, 0.5-1 parts of aminopeptidases, 1-2 parts of chamomiles are extracted
Object, 1-2 part licorice, 1-3 parts of yeast polypeptides, 2-4 parts of tip edge bladder-wrack extracts, 1-3 parts of oligopeptides -20,0.5-1 parts of cards
Wave nurse, 0.6-2 part aminomethyl propanol, 3-6 parts of propylene glycol, 3-6 parts of 1,3 butylene glycols, 0.5-1 parts of Cremophor RH40s,
0.5-1 parts of blumea oils, 0.5-1 parts of glycerol caprylates, 0.1-0.2 parts of methyl hydroxybenzoates, 0.1-0.2 parts of allantoins, 0.02-0.1
Part EDETATE SODIUM, 0.03-0.1 parts of Sodium Hyaluronates, 70-100 parts of deionized waters.
2. the preparation method that a kind of pore as described in claim 1 shrinks Essence, which is characterized in that include the following steps:
Step 1:It takes tealeaves to crush, crosses 80 meshes, obtain tea powder, accurately weighed tea powder 4g, with 25% ethyl alcohol of 120mL volumetric concentration
Solution-wet is added by cellulase and pectase in mass ratio 1:The complex enzyme 6mg of 1 composition, is placed in 50 DEG C of waters bath with thermostatic control
Completely cut off air stirring 30min, extracted under conditions of 50 DEG C, microwave power 400W, gained extract liquor is diluted 5 times and stands
10min draws supernatant liquor, both obtains tea polyphenol extract object;
Step 2:Weigh in deionized water to water phase pot, sequentially add the measured EDETATE SODIUM of accurate scale, Sodium Hyaluronate,
Carbomer, and heating mixes while stirring, is sufficiently stirred and is uniformly dissolved under temperature 60 C, sequentially adds propylene glycol, 1,3- fourth
Glycol, methyl hydroxybenzoate, allantoin, temperature 60 C keep the temperature 30 minutes;
Step 3:In temperature 60 C, material in water phase pot is pumped into vacuum emulsifying pot, is sequentially added under stirring
Tea polyphenol extract object, propolis extract, protease, aminopeptidase, camomile extract, licorice, double sweet ammonia skins, yeast
Polypeptide, tip edge bladder-wrack extract, oligopeptides -20 stir 30 minutes, are sufficiently mixed uniformly;
Step 4:It cools, when temperature drops to 45 DEG C, Cremophor RH40, blumea oil, sad glycerol is added
Ester, and stir;
Step 5:Continue to cool down, when temperature drops to 35 DEG C, aminomethyl propanol is added, and stir, is cooled to
Room temperature is to get Essence.
3. the preparation method that a kind of pore according to claim 2 shrinks Essence, it is characterised in that:The propolis mentions
Taking object is nanometer supercritical bee-glue.
4. the preparation method that a kind of pore according to claim 3 shrinks Essence, it is characterised in that:The nanometer is super
Critical propolis is the nanometer supercritical bee-glue being process by Phospholipids nano-encapsulated technology.
5. the preparation method that a kind of pore according to claim 2 shrinks Essence, which is characterized in that the Radix Glycyrrhizae mentions
Object is taken to prepare using following methods:5g licorice medicinal materials are crushed, sieving, obtain powder, the NaOH that concentration is 0.2mol/L is added
Aqueous solution is 1 by solid-to-liquid ratio:The mixing of 10 ratios, 2h is extracted in hot dipping at 80 DEG C, is repeated 2 times, and is filtered, and quality is added in filtrate
Concentration is 3% hydrochloric acid tune pH value to 1-2.5, is centrifugated under the revolving speed of 4000r/min, goes supernatant to obtain sediment, as
Licorice.
6. the preparation method that a kind of pore according to claim 2 shrinks Essence, which is characterized in that the chamomile
Extract is prepared using following methods:5g chamomile is crushed, sieving, obtain powder, the NaOH that concentration is 0.2mol/L is added
Aqueous solution is 1 by solid-to-liquid ratio:The mixing of 10 ratios, 2h is extracted in hot dipping at 80 DEG C, is repeated 2 times, and is filtered, and quality is added in filtrate
Concentration is 3% hydrochloric acid tune pH value to 1-2.5, is centrifugated under the revolving speed of 4000r/min, goes supernatant to obtain sediment, as
Camomile extract.
7. the preparation method that a kind of pore according to claim 2 shrinks Essence, which is characterized in that the tip edge ink
Angle algae extract is prepared using following methods:Tip edge bladder-wrack is washed, be placed at aeration-drying carry out it is air-dried, by wind
Tip edge bladder-wrack after dry is placed in micro-wave oven, and the tip edge bladder-wrack after drying is put into powder in pulverizer by the dry 4min of moderate heat
It is broken, smashed tip edge bladder-wrack is crossed into 60 meshes, obtains tip edge bladder-wrack powder, weighs tip edge bladder-wrack powder 10g, deionized water
100g is added to the container, and is decocted at 90 DEG C and is extracted 100min, and the substance in container is all taken out, is cooled to room temperature, use is low
Warm refrigerated centrifuge filtering, revolving speed 3000r/min, centrifugation time 5min collect supernatant, and tip edge bladder-wrack is obtained after filtering and is mentioned
Take object.
8. the preparation method that a kind of pore according to claim 7 shrinks Essence, it is characterised in that:Described is filtered into
Three layers of filtered through gauze.
9. the preparation method that a kind of pore according to claim 8 shrinks Essence, it is characterised in that:Three layers of yarn
It is filtered after cloth filtering using the membrane filter in 0.2 μm of aperture.
10. the preparation method that a kind of pore according to claim 5 or 6 shrinks Essence, it is characterised in that:The powder
Sieving was 40 meshes after broken.
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