CN103842031B - 包含凝胶网络的洗发剂组合物 - Google Patents
包含凝胶网络的洗发剂组合物 Download PDFInfo
- Publication number
- CN103842031B CN103842031B CN201280048467.2A CN201280048467A CN103842031B CN 103842031 B CN103842031 B CN 103842031B CN 201280048467 A CN201280048467 A CN 201280048467A CN 103842031 B CN103842031 B CN 103842031B
- Authority
- CN
- China
- Prior art keywords
- shampoo compositions
- weight
- surfactant
- shampoo
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 265
- 239000002453 shampoo Substances 0.000 title claims abstract description 155
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 73
- 150000002191 fatty alcohols Chemical class 0.000 claims abstract description 49
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims abstract description 39
- 230000003213 activating effect Effects 0.000 claims abstract description 39
- SFNALCNOMXIBKG-UHFFFAOYSA-N ethylene glycol monododecyl ether Chemical compound CCCCCCCCCCCCOCCO SFNALCNOMXIBKG-UHFFFAOYSA-N 0.000 claims abstract description 35
- 230000007704 transition Effects 0.000 claims abstract description 27
- 229910052938 sodium sulfate Inorganic materials 0.000 claims abstract description 23
- 235000011152 sodium sulphate Nutrition 0.000 claims abstract description 23
- 239000004064 cosurfactant Substances 0.000 claims abstract description 14
- 238000000113 differential scanning calorimetry Methods 0.000 claims abstract description 12
- 239000008365 aqueous carrier Substances 0.000 claims abstract description 11
- 239000002736 nonionic surfactant Substances 0.000 claims abstract description 10
- 239000002280 amphoteric surfactant Substances 0.000 claims abstract description 8
- 239000002888 zwitterionic surfactant Substances 0.000 claims abstract description 6
- -1 ethanol amide Chemical class 0.000 claims description 75
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 58
- 239000004094 surface-active agent Substances 0.000 claims description 55
- 238000000034 method Methods 0.000 claims description 25
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims description 22
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 claims description 19
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N EtOH Substances CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 18
- 229960003237 betaine Drugs 0.000 claims description 13
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical group C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims description 12
- 238000002844 melting Methods 0.000 claims description 12
- 230000008018 melting Effects 0.000 claims description 12
- 239000003945 anionic surfactant Substances 0.000 claims description 11
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 claims description 11
- 239000011734 sodium Substances 0.000 claims description 11
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 9
- 229960000541 cetyl alcohol Drugs 0.000 claims description 9
- 230000000694 effects Effects 0.000 claims description 9
- 229910052708 sodium Inorganic materials 0.000 claims description 9
- 241001044369 Amphion Species 0.000 claims description 8
- 125000000129 anionic group Chemical group 0.000 claims description 8
- 238000009529 body temperature measurement Methods 0.000 claims description 6
- 239000003513 alkali Substances 0.000 claims description 5
- 235000009508 confectionery Nutrition 0.000 claims description 5
- 244000060011 Cocos nucifera Species 0.000 claims description 4
- 235000013162 Cocos nucifera Nutrition 0.000 claims description 4
- NOPFSRXAKWQILS-UHFFFAOYSA-N docosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCO NOPFSRXAKWQILS-UHFFFAOYSA-N 0.000 claims description 4
- 150000001875 compounds Chemical class 0.000 claims description 3
- RZYKUPXRYIOEME-UHFFFAOYSA-N CCCCCCCCCCCC[S] Chemical group CCCCCCCCCCCC[S] RZYKUPXRYIOEME-UHFFFAOYSA-N 0.000 claims description 2
- 244000269722 Thea sinensis Species 0.000 claims description 2
- 229960000735 docosanol Drugs 0.000 claims description 2
- 230000009466 transformation Effects 0.000 claims description 2
- 229940012831 stearyl alcohol Drugs 0.000 claims 1
- 125000000020 sulfo group Chemical group O=S(=O)([*])O[H] 0.000 claims 1
- 210000004209 hair Anatomy 0.000 description 54
- 239000000463 material Substances 0.000 description 21
- 150000001412 amines Chemical class 0.000 description 20
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 18
- 125000004432 carbon atom Chemical group C* 0.000 description 18
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 18
- 229920005573 silicon-containing polymer Polymers 0.000 description 18
- 230000009286 beneficial effect Effects 0.000 description 16
- 239000002585 base Substances 0.000 description 15
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 14
- 125000000217 alkyl group Chemical group 0.000 description 14
- 150000001450 anions Chemical class 0.000 description 14
- 239000000047 product Substances 0.000 description 14
- 239000002904 solvent Substances 0.000 description 13
- 230000003750 conditioning effect Effects 0.000 description 12
- 229920000642 polymer Polymers 0.000 description 12
- QZXSMBBFBXPQHI-UHFFFAOYSA-N N-(dodecanoyl)ethanolamine Chemical compound CCCCCCCCCCCC(=O)NCCO QZXSMBBFBXPQHI-UHFFFAOYSA-N 0.000 description 11
- 239000002253 acid Substances 0.000 description 11
- 235000002639 sodium chloride Nutrition 0.000 description 11
- 235000019197 fats Nutrition 0.000 description 10
- 239000006260 foam Substances 0.000 description 10
- 239000007788 liquid Substances 0.000 description 10
- 239000003921 oil Substances 0.000 description 10
- 229940060184 oil ingredients Drugs 0.000 description 10
- 235000019198 oils Nutrition 0.000 description 10
- HIXDQWDOVZUNNA-UHFFFAOYSA-N 2-(3,4-dimethoxyphenyl)-5-hydroxy-7-methoxychromen-4-one Chemical compound C=1C(OC)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=C(OC)C(OC)=C1 HIXDQWDOVZUNNA-UHFFFAOYSA-N 0.000 description 9
- 244000303965 Cyamopsis psoralioides Species 0.000 description 9
- 235000019270 ammonium chloride Nutrition 0.000 description 9
- 230000008021 deposition Effects 0.000 description 9
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 9
- 229940057950 sodium laureth sulfate Drugs 0.000 description 9
- SXHLENDCVBIJFO-UHFFFAOYSA-M sodium;2-[2-(2-dodecoxyethoxy)ethoxy]ethyl sulfate Chemical compound [Na+].CCCCCCCCCCCCOCCOCCOCCOS([O-])(=O)=O SXHLENDCVBIJFO-UHFFFAOYSA-M 0.000 description 9
- 239000004166 Lanolin Substances 0.000 description 8
- 229920002884 Laureth 4 Polymers 0.000 description 8
- 229920006317 cationic polymer Polymers 0.000 description 8
- 229940039717 lanolin Drugs 0.000 description 8
- 235000019388 lanolin Nutrition 0.000 description 8
- 229940061515 laureth-4 Drugs 0.000 description 8
- 239000002245 particle Substances 0.000 description 8
- 150000003839 salts Chemical class 0.000 description 8
- 239000007787 solid Substances 0.000 description 8
- FPVVYTCTZKCSOJ-UHFFFAOYSA-N Ethylene glycol distearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCOC(=O)CCCCCCCCCCCCCCCCC FPVVYTCTZKCSOJ-UHFFFAOYSA-N 0.000 description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 7
- 125000001931 aliphatic group Chemical group 0.000 description 7
- 125000002091 cationic group Chemical group 0.000 description 7
- 239000002537 cosmetic Substances 0.000 description 7
- 239000013078 crystal Substances 0.000 description 7
- 238000009826 distribution Methods 0.000 description 7
- 150000002148 esters Chemical class 0.000 description 7
- 229940100608 glycol distearate Drugs 0.000 description 7
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 7
- 235000019341 magnesium sulphate Nutrition 0.000 description 7
- 238000005259 measurement Methods 0.000 description 7
- 238000002360 preparation method Methods 0.000 description 7
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 7
- 239000004299 sodium benzoate Substances 0.000 description 7
- 235000010234 sodium benzoate Nutrition 0.000 description 7
- 229940117986 sulfobetaine Drugs 0.000 description 7
- 239000000375 suspending agent Substances 0.000 description 7
- 208000001840 Dandruff Diseases 0.000 description 6
- 230000015572 biosynthetic process Effects 0.000 description 6
- 239000003792 electrolyte Substances 0.000 description 6
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 5
- 241001597008 Nomeidae Species 0.000 description 5
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 5
- 239000003093 cationic surfactant Substances 0.000 description 5
- 238000004140 cleaning Methods 0.000 description 5
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 5
- 125000000400 lauroyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 5
- 238000002156 mixing Methods 0.000 description 5
- 210000004761 scalp Anatomy 0.000 description 5
- 230000035807 sensation Effects 0.000 description 5
- 235000019615 sensations Nutrition 0.000 description 5
- 229920002545 silicone oil Polymers 0.000 description 5
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 description 4
- OVSKIKFHRZPJSS-UHFFFAOYSA-N 2,4-D Chemical compound OC(=O)COC1=CC=C(Cl)C=C1Cl OVSKIKFHRZPJSS-UHFFFAOYSA-N 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 239000011149 active material Substances 0.000 description 4
- 125000002252 acyl group Chemical group 0.000 description 4
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 4
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 4
- 235000011130 ammonium sulphate Nutrition 0.000 description 4
- 239000004359 castor oil Substances 0.000 description 4
- 235000019438 castor oil Nutrition 0.000 description 4
- 239000006071 cream Substances 0.000 description 4
- 238000002425 crystallisation Methods 0.000 description 4
- 230000008025 crystallization Effects 0.000 description 4
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 4
- 235000019580 granularity Nutrition 0.000 description 4
- 229930195733 hydrocarbon Natural products 0.000 description 4
- 150000002430 hydrocarbons Chemical class 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 230000003020 moisturizing effect Effects 0.000 description 4
- 239000000178 monomer Substances 0.000 description 4
- 235000013599 spices Nutrition 0.000 description 4
- TYWMIZZBOVGFOV-UHFFFAOYSA-N tetracosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCCCO TYWMIZZBOVGFOV-UHFFFAOYSA-N 0.000 description 4
- 239000000080 wetting agent Substances 0.000 description 4
- DWHIUNMOTRUVPG-UHFFFAOYSA-N 2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol Chemical compound CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCO DWHIUNMOTRUVPG-UHFFFAOYSA-N 0.000 description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 3
- 239000004215 Carbon black (E152) Substances 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- 239000004348 Glyceryl diacetate Substances 0.000 description 3
- 206010019049 Hair texture abnormal Diseases 0.000 description 3
- 229910019142 PO4 Inorganic materials 0.000 description 3
- 241000282372 Panthera onca Species 0.000 description 3
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 229930006000 Sucrose Natural products 0.000 description 3
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 3
- QYKIQEUNHZKYBP-UHFFFAOYSA-N Vinyl ether Chemical compound C=COC=C QYKIQEUNHZKYBP-UHFFFAOYSA-N 0.000 description 3
- 150000001768 cations Chemical class 0.000 description 3
- 125000004122 cyclic group Chemical group 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 235000019443 glyceryl diacetate Nutrition 0.000 description 3
- 238000000227 grinding Methods 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 230000002209 hydrophobic effect Effects 0.000 description 3
- 229940031674 laureth-7 Drugs 0.000 description 3
- 230000000474 nursing effect Effects 0.000 description 3
- 239000010452 phosphate Substances 0.000 description 3
- 229920001296 polysiloxane Polymers 0.000 description 3
- 239000011591 potassium Substances 0.000 description 3
- 229910052700 potassium Inorganic materials 0.000 description 3
- 239000003755 preservative agent Substances 0.000 description 3
- 230000002335 preservative effect Effects 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- FSYKKLYZXJSNPZ-UHFFFAOYSA-N sarcosine Chemical compound C[NH2+]CC([O-])=O FSYKKLYZXJSNPZ-UHFFFAOYSA-N 0.000 description 3
- 210000002374 sebum Anatomy 0.000 description 3
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 239000005720 sucrose Substances 0.000 description 3
- 238000003786 synthesis reaction Methods 0.000 description 3
- 235000019587 texture Nutrition 0.000 description 3
- 229930003231 vitamin Natural products 0.000 description 3
- 235000013343 vitamin Nutrition 0.000 description 3
- 239000011782 vitamin Substances 0.000 description 3
- 229940088594 vitamin Drugs 0.000 description 3
- 150000003722 vitamin derivatives Chemical class 0.000 description 3
- 238000009736 wetting Methods 0.000 description 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 2
- MRAMPOPITCOOIN-VIFPVBQESA-N (2r)-n-(3-ethoxypropyl)-2,4-dihydroxy-3,3-dimethylbutanamide Chemical compound CCOCCCNC(=O)[C@H](O)C(C)(C)CO MRAMPOPITCOOIN-VIFPVBQESA-N 0.000 description 2
- YWWVWXASSLXJHU-AATRIKPKSA-N (9E)-tetradecenoic acid Chemical compound CCCC\C=C\CCCCCCCC(O)=O YWWVWXASSLXJHU-AATRIKPKSA-N 0.000 description 2
- ALSTYHKOOCGGFT-KTKRTIGZSA-N (9Z)-octadecen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 description 2
- XDOFQFKRPWOURC-UHFFFAOYSA-N 16-methylheptadecanoic acid Chemical compound CC(C)CCCCCCCCCCCCCCC(O)=O XDOFQFKRPWOURC-UHFFFAOYSA-N 0.000 description 2
- FKOKUHFZNIUSLW-UHFFFAOYSA-N 2-Hydroxypropyl stearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(C)O FKOKUHFZNIUSLW-UHFFFAOYSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 235000016068 Berberis vulgaris Nutrition 0.000 description 2
- 241000335053 Beta vulgaris Species 0.000 description 2
- QIWQBXPUPMUKMD-UHFFFAOYSA-N C(C)OCCCCCCCCC(C)OC(C)CCCCCCCCOCC Chemical class C(C)OCCCCCCCCC(C)OC(C)CCCCCCCCOCC QIWQBXPUPMUKMD-UHFFFAOYSA-N 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 description 2
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 description 2
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 description 2
- ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical class [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 description 2
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 2
- 235000019082 Osmanthus Nutrition 0.000 description 2
- 241000333181 Osmanthus Species 0.000 description 2
- 235000019482 Palm oil Nutrition 0.000 description 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 2
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 2
- 238000002441 X-ray diffraction Methods 0.000 description 2
- 230000021736 acetylation Effects 0.000 description 2
- 238000006640 acetylation reaction Methods 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 150000001335 aliphatic alkanes Chemical class 0.000 description 2
- 125000003342 alkenyl group Chemical group 0.000 description 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
- 235000001014 amino acid Nutrition 0.000 description 2
- 229940024606 amino acid Drugs 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 description 2
- 125000003118 aryl group Chemical group 0.000 description 2
- 239000003212 astringent agent Substances 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- JPNZKPRONVOMLL-UHFFFAOYSA-N azane;octadecanoic acid Chemical class [NH4+].CCCCCCCCCCCCCCCCCC([O-])=O JPNZKPRONVOMLL-UHFFFAOYSA-N 0.000 description 2
- 230000003796 beauty Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- 239000002738 chelating agent Substances 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 239000000084 colloidal system Substances 0.000 description 2
- 239000003086 colorant Substances 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- 229940086555 cyclomethicone Drugs 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 235000014113 dietary fatty acids Nutrition 0.000 description 2
- 239000003085 diluting agent Substances 0.000 description 2
- SNRUBQQJIBEYMU-UHFFFAOYSA-N dodecane Chemical compound CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 description 2
- SYELZBGXAIXKHU-UHFFFAOYSA-N dodecyldimethylamine N-oxide Chemical compound CCCCCCCCCCCC[N+](C)(C)[O-] SYELZBGXAIXKHU-UHFFFAOYSA-N 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- ZQPPMHVWECSIRJ-MDZDMXLPSA-N elaidic acid Chemical compound CCCCCCCC\C=C\CCCCCCCC(O)=O ZQPPMHVWECSIRJ-MDZDMXLPSA-N 0.000 description 2
- 239000003995 emulsifying agent Substances 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- 125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 description 2
- 238000007046 ethoxylation reaction Methods 0.000 description 2
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 239000000194 fatty acid Substances 0.000 description 2
- 229930195729 fatty acid Natural products 0.000 description 2
- 150000004665 fatty acids Chemical class 0.000 description 2
- 150000002194 fatty esters Chemical class 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 235000011187 glycerol Nutrition 0.000 description 2
- 229940074046 glyceryl laurate Drugs 0.000 description 2
- DXTIKTAIYCJTII-UHFFFAOYSA-N guanidine acetate Chemical compound CC([O-])=O.NC([NH3+])=N DXTIKTAIYCJTII-UHFFFAOYSA-N 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 230000001771 impaired effect Effects 0.000 description 2
- 150000002500 ions Chemical class 0.000 description 2
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 2
- MOYKHGMNXAOIAT-JGWLITMVSA-N isosorbide dinitrate Chemical compound [O-][N+](=O)O[C@H]1CO[C@@H]2[C@H](O[N+](=O)[O-])CO[C@@H]21 MOYKHGMNXAOIAT-JGWLITMVSA-N 0.000 description 2
- 229960000201 isosorbide dinitrate Drugs 0.000 description 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 2
- 229940049964 oleate Drugs 0.000 description 2
- 229940055577 oleyl alcohol Drugs 0.000 description 2
- XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 239000003002 pH adjusting agent Substances 0.000 description 2
- 239000002540 palm oil Substances 0.000 description 2
- SECPZKHBENQXJG-FPLPWBNLSA-N palmitoleic acid Chemical compound CCCCCC\C=C/CCCCCCCC(O)=O SECPZKHBENQXJG-FPLPWBNLSA-N 0.000 description 2
- 229940101267 panthenol Drugs 0.000 description 2
- 229940055726 pantothenic acid Drugs 0.000 description 2
- 235000019161 pantothenic acid Nutrition 0.000 description 2
- 239000011713 pantothenic acid Substances 0.000 description 2
- 235000020957 pantothenol Nutrition 0.000 description 2
- 239000011619 pantothenol Substances 0.000 description 2
- 239000012188 paraffin wax Substances 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 2
- 239000000419 plant extract Substances 0.000 description 2
- OTYBMLCTZGSZBG-UHFFFAOYSA-L potassium sulfate Chemical compound [K+].[K+].[O-]S([O-])(=O)=O OTYBMLCTZGSZBG-UHFFFAOYSA-L 0.000 description 2
- 229910052939 potassium sulfate Inorganic materials 0.000 description 2
- 235000011151 potassium sulphates Nutrition 0.000 description 2
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 description 2
- ARIWANIATODDMH-UHFFFAOYSA-N rac-1-monolauroylglycerol Chemical compound CCCCCCCCCCCC(=O)OCC(O)CO ARIWANIATODDMH-UHFFFAOYSA-N 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 239000006254 rheological additive Substances 0.000 description 2
- 229940095673 shampoo product Drugs 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 229940079862 sodium lauryl sarcosinate Drugs 0.000 description 2
- ADWNFGORSPBALY-UHFFFAOYSA-M sodium;2-[dodecyl(methyl)amino]acetate Chemical compound [Na+].CCCCCCCCCCCCN(C)CC([O-])=O ADWNFGORSPBALY-UHFFFAOYSA-M 0.000 description 2
- 235000012424 soybean oil Nutrition 0.000 description 2
- 239000003549 soybean oil Substances 0.000 description 2
- 125000001424 substituent group Chemical group 0.000 description 2
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 2
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 2
- 125000002889 tridecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- 229940099259 vaseline Drugs 0.000 description 2
- 239000001993 wax Substances 0.000 description 2
- WTVHAMTYZJGJLJ-UHFFFAOYSA-N (+)-(4S,8R)-8-epi-beta-bisabolol Natural products CC(C)=CCCC(C)C1(O)CCC(C)=CC1 WTVHAMTYZJGJLJ-UHFFFAOYSA-N 0.000 description 1
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 1
- RGZSQWQPBWRIAQ-CABCVRRESA-N (-)-alpha-Bisabolol Chemical compound CC(C)=CCC[C@](C)(O)[C@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-CABCVRRESA-N 0.000 description 1
- OMDQUFIYNPYJFM-XKDAHURESA-N (2r,3r,4s,5r,6s)-2-(hydroxymethyl)-6-[[(2r,3s,4r,5s,6r)-4,5,6-trihydroxy-3-[(2s,3s,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]methoxy]oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@H](O)[C@H](O)O1 OMDQUFIYNPYJFM-XKDAHURESA-N 0.000 description 1
- DWNBOPVKNPVNQG-LURJTMIESA-N (2s)-4-hydroxy-2-(propylamino)butanoic acid Chemical compound CCCN[C@H](C(O)=O)CCO DWNBOPVKNPVNQG-LURJTMIESA-N 0.000 description 1
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 description 1
- 150000005208 1,4-dihydroxybenzenes Chemical class 0.000 description 1
- RZRNAYUHWVFMIP-KTKRTIGZSA-N 1-oleoylglycerol Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(O)CO RZRNAYUHWVFMIP-KTKRTIGZSA-N 0.000 description 1
- 229940094997 1-tetracosanol Drugs 0.000 description 1
- ULQISTXYYBZJSJ-UHFFFAOYSA-N 12-hydroxyoctadecanoic acid Chemical compound CCCCCCC(O)CCCCCCCCCCC(O)=O ULQISTXYYBZJSJ-UHFFFAOYSA-N 0.000 description 1
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- ZLNYGUMWTNIUQV-UHFFFAOYSA-N 2,3-dihydroxypropyl dodecanoate;sodium;sulfuric acid Chemical compound [Na].OS(O)(=O)=O.CCCCCCCCCCCC(=O)OCC(O)CO ZLNYGUMWTNIUQV-UHFFFAOYSA-N 0.000 description 1
- AZLWQVJVINEILY-UHFFFAOYSA-N 2-(2-dodecoxyethoxy)ethanol Chemical compound CCCCCCCCCCCCOCCOCCO AZLWQVJVINEILY-UHFFFAOYSA-N 0.000 description 1
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 1
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 description 1
- KIHBGTRZFAVZRV-UHFFFAOYSA-N 2-Hydroxyoctadecanoic acid Natural products CCCCCCCCCCCCCCCCC(O)C(O)=O KIHBGTRZFAVZRV-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- KLFVDTRVIFNWIH-UHFFFAOYSA-N 2-[2-(2-tridecoxyethoxy)ethoxy]ethanol Chemical compound CCCCCCCCCCCCCOCCOCCOCCO KLFVDTRVIFNWIH-UHFFFAOYSA-N 0.000 description 1
- RZRILSWMGXWSJY-UHFFFAOYSA-N 2-[bis(2-hydroxyethyl)amino]ethanol;sulfuric acid Chemical compound OS(O)(=O)=O.OCCN(CCO)CCO RZRILSWMGXWSJY-UHFFFAOYSA-N 0.000 description 1
- AMRBZKOCOOPYNY-QXMHVHEDSA-N 2-[dimethyl-[(z)-octadec-9-enyl]azaniumyl]acetate Chemical compound CCCCCCCC\C=C/CCCCCCCC[N+](C)(C)CC([O-])=O AMRBZKOCOOPYNY-QXMHVHEDSA-N 0.000 description 1
- RFVNOJDQRGSOEL-UHFFFAOYSA-N 2-hydroxyethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCO RFVNOJDQRGSOEL-UHFFFAOYSA-N 0.000 description 1
- BJRXGOFKVBOFCO-UHFFFAOYSA-N 2-hydroxypropyl 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OCC(C)O BJRXGOFKVBOFCO-UHFFFAOYSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- ONDJNAKJCWJYSX-UHFFFAOYSA-N 3-(dodecylamino)propane-1-sulfonic acid Chemical class CCCCCCCCCCCC[NH2+]CCCS([O-])(=O)=O ONDJNAKJCWJYSX-UHFFFAOYSA-N 0.000 description 1
- VFKZECOCJCGZQK-UHFFFAOYSA-M 3-hydroxypropyl(trimethyl)azanium;chloride Chemical compound [Cl-].C[N+](C)(C)CCCO VFKZECOCJCGZQK-UHFFFAOYSA-M 0.000 description 1
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- YWWVWXASSLXJHU-UHFFFAOYSA-N 9E-tetradecenoic acid Natural products CCCCC=CCCCCCCCC(O)=O YWWVWXASSLXJHU-UHFFFAOYSA-N 0.000 description 1
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 1
- 235000019489 Almond oil Nutrition 0.000 description 1
- 241001116389 Aloe Species 0.000 description 1
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 description 1
- CNOPDZWOYFOHGN-BQYQJAHWSA-N Beta-Ionol Chemical compound CC(O)\C=C\C1=C(C)CCCC1(C)C CNOPDZWOYFOHGN-BQYQJAHWSA-N 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 description 1
- TXNJAVCZNMSELK-UHFFFAOYSA-N CCCCCCCCCCCCOC(=O)CNC Chemical compound CCCCCCCCCCCCOC(=O)CNC TXNJAVCZNMSELK-UHFFFAOYSA-N 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- 239000001884 Cassia gum Substances 0.000 description 1
- NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 241000723346 Cinnamomum camphora Species 0.000 description 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 description 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- 239000005770 Eugenol Substances 0.000 description 1
- 239000004606 Fillers/Extenders Substances 0.000 description 1
- 229920000926 Galactomannan Polymers 0.000 description 1
- 241000208680 Hamamelis mollis Species 0.000 description 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
- SHBUUTHKGIVMJT-UHFFFAOYSA-N Hydroxystearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OO SHBUUTHKGIVMJT-UHFFFAOYSA-N 0.000 description 1
- 229940124091 Keratolytic Drugs 0.000 description 1
- MLSJBGYKDYSOAE-DCWMUDTNSA-N L-Ascorbic acid-2-glucoside Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)=C1O MLSJBGYKDYSOAE-DCWMUDTNSA-N 0.000 description 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 description 1
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 description 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 description 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 description 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 1
- 239000004472 Lysine Substances 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 229920000881 Modified starch Polymers 0.000 description 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 1
- AFCARXCZXQIEQB-UHFFFAOYSA-N N-[3-oxo-3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(CCNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 AFCARXCZXQIEQB-UHFFFAOYSA-N 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- 235000021319 Palmitoleic acid Nutrition 0.000 description 1
- 235000019483 Peanut oil Nutrition 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- QOSMNYMQXIVWKY-UHFFFAOYSA-N Propyl levulinate Chemical compound CCCOC(=O)CCC(C)=O QOSMNYMQXIVWKY-UHFFFAOYSA-N 0.000 description 1
- UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 description 1
- LKVZSCFGTYHYBT-UHFFFAOYSA-N S(=O)(=O)(O)O.C(CCCCCCCCCCC)(=O)[Na] Chemical compound S(=O)(=O)(O)O.C(CCCCCCCCCCC)(=O)[Na] LKVZSCFGTYHYBT-UHFFFAOYSA-N 0.000 description 1
- PHIIYDSPMYGDAF-UHFFFAOYSA-N S(=O)(=O)(O)O.C(CCCCCCCCCCC)[K] Chemical compound S(=O)(=O)(O)O.C(CCCCCCCCCCC)[K] PHIIYDSPMYGDAF-UHFFFAOYSA-N 0.000 description 1
- 235000019485 Safflower oil Nutrition 0.000 description 1
- 108010077895 Sarcosine Proteins 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-N Sulfurous acid Chemical compound OS(O)=O LSNNMFCWUKXFEE-UHFFFAOYSA-N 0.000 description 1
- 239000005864 Sulphur Substances 0.000 description 1
- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 description 1
- PHYFQTYBJUILEZ-UHFFFAOYSA-N Trioleoylglycerol Natural products CCCCCCCCC=CCCCCCCCC(=O)OCC(OC(=O)CCCCCCCC=CCCCCCCCC)COC(=O)CCCCCCCC=CCCCCCCCC PHYFQTYBJUILEZ-UHFFFAOYSA-N 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 229930003451 Vitamin B1 Natural products 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 229930003316 Vitamin D Natural products 0.000 description 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 1
- UJNOLBSYLSYIBM-WISYIIOYSA-N [(1r,2s,5r)-5-methyl-2-propan-2-ylcyclohexyl] (2r)-2-hydroxypropanoate Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)[C@@H](C)O UJNOLBSYLSYIBM-WISYIIOYSA-N 0.000 description 1
- GCSPRLPXTPMSTL-IBDNADADSA-N [(2s,3r,4s,5s,6r)-2-[(2s,3s,4s,5r)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] dodecanoate Chemical compound CCCCCCCCCCCC(=O)O[C@@]1([C@]2(CO)[C@H]([C@H](O)[C@@H](CO)O2)O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O GCSPRLPXTPMSTL-IBDNADADSA-N 0.000 description 1
- QAKVQPVSNCRRGJ-UHFFFAOYSA-N [I].C(CCC)NC(O)=O Chemical compound [I].C(CCC)NC(O)=O QAKVQPVSNCRRGJ-UHFFFAOYSA-N 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000003044 adaptive effect Effects 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 235000004279 alanine Nutrition 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- 150000005215 alkyl ethers Chemical class 0.000 description 1
- 125000005376 alkyl siloxane group Chemical group 0.000 description 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- 229960000458 allantoin Drugs 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 239000008168 almond oil Substances 0.000 description 1
- 235000011399 aloe vera Nutrition 0.000 description 1
- RGZSQWQPBWRIAQ-LSDHHAIUSA-N alpha-Bisabolol Natural products CC(C)=CCC[C@@](C)(O)[C@@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-LSDHHAIUSA-N 0.000 description 1
- OBETXYAYXDNJHR-UHFFFAOYSA-N alpha-ethylcaproic acid Natural products CCCCC(CC)C(O)=O OBETXYAYXDNJHR-UHFFFAOYSA-N 0.000 description 1
- 125000003368 amide group Chemical group 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- BTBJBAZGXNKLQC-UHFFFAOYSA-N ammonium lauryl sulfate Chemical compound [NH4+].CCCCCCCCCCCCOS([O-])(=O)=O BTBJBAZGXNKLQC-UHFFFAOYSA-N 0.000 description 1
- 229940063953 ammonium lauryl sulfate Drugs 0.000 description 1
- 229940035676 analgesics Drugs 0.000 description 1
- 239000000730 antalgic agent Substances 0.000 description 1
- 239000000058 anti acne agent Substances 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 229940124340 antiacne agent Drugs 0.000 description 1
- 239000003429 antifungal agent Substances 0.000 description 1
- 229940121375 antifungal agent Drugs 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 239000003125 aqueous solvent Substances 0.000 description 1
- 229940114079 arachidonic acid Drugs 0.000 description 1
- 235000021342 arachidonic acid Nutrition 0.000 description 1
- BTFJIXJJCSYFAL-UHFFFAOYSA-N arachidyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCO BTFJIXJJCSYFAL-UHFFFAOYSA-N 0.000 description 1
- 229940067599 ascorbyl glucoside Drugs 0.000 description 1
- 235000009582 asparagine Nutrition 0.000 description 1
- 229960001230 asparagine Drugs 0.000 description 1
- 235000003704 aspartic acid Nutrition 0.000 description 1
- 125000004429 atom Chemical group 0.000 description 1
- 235000021302 avocado oil Nutrition 0.000 description 1
- 239000008163 avocado oil Substances 0.000 description 1
- 150000003851 azoles Chemical class 0.000 description 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 description 1
- CNOPDZWOYFOHGN-UHFFFAOYSA-N beta-ionol Natural products CC(O)C=CC1=C(C)CCCC1(C)C CNOPDZWOYFOHGN-UHFFFAOYSA-N 0.000 description 1
- 235000020958 biotin Nutrition 0.000 description 1
- 239000011616 biotin Substances 0.000 description 1
- 229960002685 biotin Drugs 0.000 description 1
- MKHVZQXYWACUQC-UHFFFAOYSA-N bis(2-hydroxyethyl)azanium;dodecyl sulfate Chemical compound OCCNCCO.CCCCCCCCCCCCOS(O)(=O)=O MKHVZQXYWACUQC-UHFFFAOYSA-N 0.000 description 1
- 229940036350 bisabolol Drugs 0.000 description 1
- HHGZABIIYIWLGA-UHFFFAOYSA-N bisabolol Natural products CC1CCC(C(C)(O)CCC=C(C)C)CC1 HHGZABIIYIWLGA-UHFFFAOYSA-N 0.000 description 1
- 238000004061 bleaching Methods 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 238000007707 calorimetry Methods 0.000 description 1
- 229930008380 camphor Natural products 0.000 description 1
- 229960000846 camphor Drugs 0.000 description 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 1
- MRUAUOIMASANKQ-UHFFFAOYSA-O carboxymethyl-[3-(dodecanoylamino)propyl]-dimethylazanium Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC(O)=O MRUAUOIMASANKQ-UHFFFAOYSA-O 0.000 description 1
- 235000019318 cassia gum Nutrition 0.000 description 1
- SVURIXNDRWRAFU-OGMFBOKVSA-N cedrol Chemical compound C1[C@]23[C@H](C)CC[C@H]3C(C)(C)[C@@H]1[C@@](O)(C)CC2 SVURIXNDRWRAFU-OGMFBOKVSA-N 0.000 description 1
- 229940026455 cedrol Drugs 0.000 description 1
- PCROEXHGMUJCDB-UHFFFAOYSA-N cedrol Natural products CC1CCC2C(C)(C)C3CC(C)(O)CC12C3 PCROEXHGMUJCDB-UHFFFAOYSA-N 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 239000003638 chemical reducing agent Substances 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- SECPZKHBENQXJG-UHFFFAOYSA-N cis-palmitoleic acid Natural products CCCCCCC=CCCCCCCCC(O)=O SECPZKHBENQXJG-UHFFFAOYSA-N 0.000 description 1
- 229940031728 cocamidopropylamine oxide Drugs 0.000 description 1
- 239000003240 coconut oil Substances 0.000 description 1
- 235000019864 coconut oil Nutrition 0.000 description 1
- 229940079840 cocoyl isethionate Drugs 0.000 description 1
- 235000012716 cod liver oil Nutrition 0.000 description 1
- 239000003026 cod liver oil Substances 0.000 description 1
- 239000005515 coenzyme Substances 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 230000009514 concussion Effects 0.000 description 1
- 239000007859 condensation product Substances 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000007334 copolymerization reaction Methods 0.000 description 1
- 235000005687 corn oil Nutrition 0.000 description 1
- 239000002285 corn oil Substances 0.000 description 1
- 239000008406 cosmetic ingredient Substances 0.000 description 1
- 235000012343 cottonseed oil Nutrition 0.000 description 1
- 239000002385 cottonseed oil Substances 0.000 description 1
- 238000005202 decontamination Methods 0.000 description 1
- 230000003588 decontaminative effect Effects 0.000 description 1
- 239000013530 defoamer Substances 0.000 description 1
- 239000003398 denaturant Substances 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- JXTHNDFMNIQAHM-UHFFFAOYSA-N dichloroacetic acid Chemical compound OC(=O)C(Cl)Cl JXTHNDFMNIQAHM-UHFFFAOYSA-N 0.000 description 1
- 229960005215 dichloroacetic acid Drugs 0.000 description 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 description 1
- GPLRAVKSCUXZTP-UHFFFAOYSA-N diglycerol Chemical compound OCC(O)COCC(O)CO GPLRAVKSCUXZTP-UHFFFAOYSA-N 0.000 description 1
- OGQYPPBGSLZBEG-UHFFFAOYSA-N dimethyl(dioctadecyl)azanium Chemical compound CCCCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCCCC OGQYPPBGSLZBEG-UHFFFAOYSA-N 0.000 description 1
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 description 1
- 229940101029 dipotassium glycyrrhizinate Drugs 0.000 description 1
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 1
- JMGZBMRVDHKMKB-UHFFFAOYSA-L disodium;2-sulfobutanedioate Chemical compound [Na+].[Na+].OS(=O)(=O)C(C([O-])=O)CC([O-])=O JMGZBMRVDHKMKB-UHFFFAOYSA-L 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- DBTWFKNDNLAKOO-UHFFFAOYSA-M dodecanamide;trimethyl(propyl)azanium;chloride Chemical compound [Cl-].CCC[N+](C)(C)C.CCCCCCCCCCCC(N)=O DBTWFKNDNLAKOO-UHFFFAOYSA-M 0.000 description 1
- QVBODZPPYSSMEL-UHFFFAOYSA-N dodecyl sulfate;2-hydroxyethylazanium Chemical compound NCCO.CCCCCCCCCCCCOS(O)(=O)=O QVBODZPPYSSMEL-UHFFFAOYSA-N 0.000 description 1
- DDXLVDQZPFLQMZ-UHFFFAOYSA-M dodecyl(trimethyl)azanium;chloride Chemical compound [Cl-].CCCCCCCCCCCC[N+](C)(C)C DDXLVDQZPFLQMZ-UHFFFAOYSA-M 0.000 description 1
- JRBPAEWTRLWTQC-UHFFFAOYSA-N dodecylamine Chemical compound CCCCCCCCCCCCN JRBPAEWTRLWTQC-UHFFFAOYSA-N 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 239000008387 emulsifying waxe Substances 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000010642 eucalyptus oil Substances 0.000 description 1
- 229940044949 eucalyptus oil Drugs 0.000 description 1
- 229960002217 eugenol Drugs 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000003779 hair growth Effects 0.000 description 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 229940072106 hydroxystearate Drugs 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 150000002475 indoles Chemical class 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000002198 insoluble material Substances 0.000 description 1
- 229920000831 ionic polymer Polymers 0.000 description 1
- 229920000554 ionomer Polymers 0.000 description 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 description 1
- SVURIXNDRWRAFU-UHFFFAOYSA-N juniperanol Natural products C1C23C(C)CCC3C(C)(C)C1C(O)(C)CC2 SVURIXNDRWRAFU-UHFFFAOYSA-N 0.000 description 1
- 230000001530 keratinolytic effect Effects 0.000 description 1
- 229960004705 kojic acid Drugs 0.000 description 1
- WZNJWVWKTVETCG-UHFFFAOYSA-N kojic acid Natural products OC(=O)C(N)CN1C=CC(=O)C(O)=C1 WZNJWVWKTVETCG-UHFFFAOYSA-N 0.000 description 1
- BEJNERDRQOWKJM-UHFFFAOYSA-N kojic acid Chemical compound OCC1=CC(=O)C(O)=CO1 BEJNERDRQOWKJM-UHFFFAOYSA-N 0.000 description 1
- 238000002356 laser light scattering Methods 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 229940075468 lauramidopropyl betaine Drugs 0.000 description 1
- 229940100491 laureth-2 Drugs 0.000 description 1
- 229940094506 lauryl betaine Drugs 0.000 description 1
- 229940071204 lauryl sarcosinate Drugs 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 229960003511 macrogol Drugs 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 229940078752 magnesium ascorbyl phosphate Drugs 0.000 description 1
- 229910001425 magnesium ion Inorganic materials 0.000 description 1
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 229940041616 menthol Drugs 0.000 description 1
- 150000005217 methyl ethers Chemical class 0.000 description 1
- XJRBAMWJDBPFIM-UHFFFAOYSA-N methyl vinyl ether Chemical compound COC=C XJRBAMWJDBPFIM-UHFFFAOYSA-N 0.000 description 1
- 239000004200 microcrystalline wax Substances 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 235000010446 mineral oil Nutrition 0.000 description 1
- 235000019426 modified starch Nutrition 0.000 description 1
- 229930003658 monoterpene Natural products 0.000 description 1
- 150000002773 monoterpene derivatives Chemical class 0.000 description 1
- 235000002577 monoterpenes Nutrition 0.000 description 1
- KKXWPVVBVWBKBL-UHFFFAOYSA-N n,n-diethylethanamine;dodecyl hydrogen sulfate Chemical compound CC[NH+](CC)CC.CCCCCCCCCCCCOS([O-])(=O)=O KKXWPVVBVWBKBL-UHFFFAOYSA-N 0.000 description 1
- AFFLGGQVNFXPEV-UHFFFAOYSA-N n-decene Natural products CCCCCCCCC=C AFFLGGQVNFXPEV-UHFFFAOYSA-N 0.000 description 1
- DVEKCXOJTLDBFE-UHFFFAOYSA-N n-dodecyl-n,n-dimethylglycinate Chemical compound CCCCCCCCCCCC[N+](C)(C)CC([O-])=O DVEKCXOJTLDBFE-UHFFFAOYSA-N 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 125000004433 nitrogen atom Chemical group N* 0.000 description 1
- 239000010466 nut oil Substances 0.000 description 1
- 235000019488 nut oil Nutrition 0.000 description 1
- CNNRPFQICPFDPO-UHFFFAOYSA-N octacosan-1-ol Chemical class CCCCCCCCCCCCCCCCCCCCCCCCCCCCO CNNRPFQICPFDPO-UHFFFAOYSA-N 0.000 description 1
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 239000003605 opacifier Substances 0.000 description 1
- 230000001662 opsonic effect Effects 0.000 description 1
- 238000000399 optical microscopy Methods 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000003791 organic solvent mixture Substances 0.000 description 1
- 150000002924 oxiranes Chemical class 0.000 description 1
- 125000000963 oxybis(methylene) group Chemical group [H]C([H])(*)OC([H])([H])* 0.000 description 1
- 239000003346 palm kernel oil Substances 0.000 description 1
- 235000019865 palm kernel oil Nutrition 0.000 description 1
- 229940023735 panthenyl ethyl ether Drugs 0.000 description 1
- 229940056211 paraffin Drugs 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 229920001083 polybutene Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 229940051841 polyoxyethylene ether Drugs 0.000 description 1
- 229920000056 polyoxyethylene ether Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- FGVVTMRZYROCTH-UHFFFAOYSA-N pyridine-2-thiol N-oxide Chemical compound [O-][N+]1=CC=CC=C1S FGVVTMRZYROCTH-UHFFFAOYSA-N 0.000 description 1
- 235000008160 pyridoxine Nutrition 0.000 description 1
- 239000011677 pyridoxine Substances 0.000 description 1
- 229960002026 pyrithione Drugs 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000000518 rheometry Methods 0.000 description 1
- WBHHMMIMDMUBKC-XLNAKTSKSA-N ricinelaidic acid Chemical compound CCCCCC[C@@H](O)C\C=C\CCCCCCCC(O)=O WBHHMMIMDMUBKC-XLNAKTSKSA-N 0.000 description 1
- 229960003656 ricinoleic acid Drugs 0.000 description 1
- FEUQNCSVHBHROZ-UHFFFAOYSA-N ricinoleic acid Natural products CCCCCCC(O[Si](C)(C)C)CC=CCCCCCCCC(=O)OC FEUQNCSVHBHROZ-UHFFFAOYSA-N 0.000 description 1
- 235000005713 safflower oil Nutrition 0.000 description 1
- 239000003813 safflower oil Substances 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- VIDTVPHHDGRGAF-UHFFFAOYSA-N selenium sulfide Chemical compound [Se]=S VIDTVPHHDGRGAF-UHFFFAOYSA-N 0.000 description 1
- 229960005265 selenium sulfide Drugs 0.000 description 1
- 239000003352 sequestering agent Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 229920002050 silicone resin Polymers 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 229940045998 sodium isethionate Drugs 0.000 description 1
- KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 description 1
- 229940048109 sodium methyl cocoyl taurate Drugs 0.000 description 1
- 239000004324 sodium propionate Substances 0.000 description 1
- 235000010334 sodium propionate Nutrition 0.000 description 1
- 229960003212 sodium propionate Drugs 0.000 description 1
- SLBXZQMMERXQAL-UHFFFAOYSA-M sodium;1-dodecoxy-4-hydroxy-1,4-dioxobutane-2-sulfonate Chemical compound [Na+].CCCCCCCCCCCCOC(=O)C(S(O)(=O)=O)CC([O-])=O SLBXZQMMERXQAL-UHFFFAOYSA-M 0.000 description 1
- LADXKQRVAFSPTR-UHFFFAOYSA-M sodium;2-hydroxyethanesulfonate Chemical compound [Na+].OCCS([O-])(=O)=O LADXKQRVAFSPTR-UHFFFAOYSA-M 0.000 description 1
- 239000002195 soluble material Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 229940031439 squalene Drugs 0.000 description 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-L sulfite Chemical compound [O-]S([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-L 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 235000020238 sunflower seed Nutrition 0.000 description 1
- 239000000516 sunscreening agent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 239000003760 tallow Substances 0.000 description 1
- 229960003080 taurine Drugs 0.000 description 1
- RJSZFSOFYVMDIC-UHFFFAOYSA-N tert-butyl n,n-dimethylcarbamate Chemical compound CN(C)C(=O)OC(C)(C)C RJSZFSOFYVMDIC-UHFFFAOYSA-N 0.000 description 1
- 150000003512 tertiary amines Chemical class 0.000 description 1
- KYMBYSLLVAOCFI-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SCN1CC1=CN=C(C)N=C1N KYMBYSLLVAOCFI-UHFFFAOYSA-N 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- REZQBEBOWJAQKS-UHFFFAOYSA-N triacontan-1-ol Chemical class CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO REZQBEBOWJAQKS-UHFFFAOYSA-N 0.000 description 1
- FPLNRAYTBIFSFW-UHFFFAOYSA-N tricosan-1-ol Chemical class CCCCCCCCCCCCCCCCCCCCCCCO FPLNRAYTBIFSFW-UHFFFAOYSA-N 0.000 description 1
- KRTNITDCKAVIFI-UHFFFAOYSA-N tridecyl benzenesulfonate Chemical compound CCCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 KRTNITDCKAVIFI-UHFFFAOYSA-N 0.000 description 1
- QTUIJRIDZOSXHJ-UHFFFAOYSA-M tridecyl sulfate Chemical compound CCCCCCCCCCCCCOS([O-])(=O)=O QTUIJRIDZOSXHJ-UHFFFAOYSA-M 0.000 description 1
- HTJNEBVCZXHBNJ-XCTPRCOBSA-H trimagnesium;(2r)-2-[(1s)-1,2-dihydroxyethyl]-3,4-dihydroxy-2h-furan-5-one;diphosphate Chemical compound [Mg+2].[Mg+2].[Mg+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.OC[C@H](O)[C@H]1OC(=O)C(O)=C1O HTJNEBVCZXHBNJ-XCTPRCOBSA-H 0.000 description 1
- GETQZCLCWQTVFV-UHFFFAOYSA-N trimethylamine Chemical group CN(C)C GETQZCLCWQTVFV-UHFFFAOYSA-N 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 239000006097 ultraviolet radiation absorber Substances 0.000 description 1
- OBYIEPMKXIBQEV-UHFFFAOYSA-N undecyl hydrogen sulfate Chemical class CCCCCCCCCCCOS(O)(=O)=O OBYIEPMKXIBQEV-UHFFFAOYSA-N 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000000052 vinegar Substances 0.000 description 1
- 235000021419 vinegar Nutrition 0.000 description 1
- 239000004034 viscosity adjusting agent Substances 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000010374 vitamin B1 Nutrition 0.000 description 1
- 239000011691 vitamin B1 Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000019166 vitamin D Nutrition 0.000 description 1
- 239000011710 vitamin D Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 229940118846 witch hazel Drugs 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/463—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/737—Galactomannans, e.g. guar; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/817—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/596—Mixtures of surface active compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
Abstract
本发明提供了一种洗发剂组合物，其具有约5%至约50%的月桂基硫酸钠和月桂基聚氧乙烯醚n‑硫酸钠，具有n>1的小于3.82%的月桂基聚氧乙烯醚n‑硫酸钠。所述洗发剂组合物还包括约0.5%至约3%的辅助表面活性剂，其选自两性表面活性剂、两性离子表面活性剂和非离子表面活性剂。洗发剂组合物具有分散的凝胶网络相，其具有至少0.05%的一种或多种脂肪醇，至少0.01%的一种或多种第二表面活性剂、和水。所述洗发剂组合物还包含至少约20%的含水载体。所述洗发剂组合物还具有如根据差示扫描量热法在介于约18℃至约30℃的峰值熔融转变温度测量的约0J/g至约0.2J/g的转变焓。
Description
技术领域
本发明涉及包含分散的凝胶网络相并且包含按所述洗发剂组合物的重量计小于约3.82%的月桂基聚氧乙烯醚n-硫酸钠的洗发剂组合物，其中N>1。更具体地，本发明涉及此类洗发剂组合物，其包含大于0.5%的月桂基聚氧乙烯醚-1硫酸钠，并且具有如根据差示扫描量热法在介于约18℃至约30℃的峰值熔融转变温度下测量的约0J/g至约0.2J/g的转变焓。
背景技术
人的毛发变脏是由于其与周围环境接触并且来自头皮分泌的皮脂。弄脏的毛发导致其具有脏污的感觉和不美的外观。弄脏的毛发需要定期频繁地用洗发剂洗涤。
用洗发剂洗发通过移除过多的污垢和皮脂而清洁毛发。然而，用洗发剂洗发可留下毛发为润湿、缠结的和一般来讲不易整理的状态。一旦毛发干燥，由于移除毛发的天然油脂，其通常留下干燥、蓬乱、无光泽或卷曲的状态。
已经开发出多种方法以缓解这些洗发剂洗发后的问题。一种方法为尝试由单一产品既清洁又调理毛发的毛发洗发剂的应用。
为了在清洁洗发剂基础上提供毛发调理有益效果，已提出多种多样的调理活性物质。传统上，洗发剂已使用阳离子聚合物来形成凝聚层用于调理有益效果。然而，这些洗发剂组合物一般来讲不在干燥的毛发上递送令人满意的光滑感觉。已提出使用包含分散的脂肪醇凝胶网络相的洗发剂组合物来实现改善的润湿感觉和干调理有益效果，同时不妨碍清洁功效。然而，当表面活性剂在或靠近室温下从溶液中结晶出来时，可能出现稳定性问题。
基于前文所述，需要有可对于干燥的毛发提供改善的调理有益效果，同时不妨碍清洁功效，当干燥时，又不向毛发提供负面感觉的洗发剂。具体地，当处于干燥毛发时，需要向毛发提供持久的润湿感觉、光滑感觉和整理性控制而不留下毛发油腻感，以及当毛发为润湿时，提供柔软性和易梳理性。
发明内容
本发明涉及洗发剂组合物，包含：（a）按所述洗发剂组合物的重量计约5%至约50%的月桂基硫酸钠和月桂基聚氧乙烯醚n-硫酸钠的组合，并且按所述洗发剂组合物的重量计，月桂基聚氧乙烯醚n-硫酸钠盐小于3.82%，其中n>1；（b）按所述洗发剂组合物的重量计，约0.5%至约3%的选自两性、两性离子和非离子表面活性剂的辅助表面活性剂；（c）分散的凝胶网络相，包含：（i）按所述洗发剂组合物的重量计，至少约0.05%的一种或多种脂肪醇；（ii）按所述洗发剂组合物的重量计，至少约0.01%的一种或多种第二表面活性剂；和（iii）水；以及（d）按所述洗发剂组合物的重量计，至少约20%的含水载体；其中所述洗发剂组合物如根据差示扫描量热法在介于约18℃至约30℃的峰值熔融转变温度测量的具有约0J/g至约0.2J/g的转变焓。
本发明还涉及制备上文所述的洗发剂组合物的方法。
通过阅读本公开，本发明的这些和其它特征、方面和优点对本领域的技术人员将变得显而易见。
具体实施方式
尽管说明书通过特别指明并且清楚地要求保护本发明的权利要求作出结论，据信，本发明通过下列具体实施方式将更好地理解。
在本发明的所有实施例中，除非另外特别说明，所有的百分比均按所述组合物总体的重量计。除非另外特别说明，所有的比率均为重量比。所有的范围包括端值在内并且是可结合的。有效数字的数目既不表示对所指示的量的限制，也不表示对测量精确度的限制。除非另外特别说明，所有的数量被理解为被“约”一词修饰。除非另外指明，所有的测量被理解为在25℃和环境条件下进行，其中“环境条件”是指在约一个大气压和约50%相对湿度的条件下。除非另外指明，所有与所列成分相关的此类重量均基于活性物质的含量计，并且不包括可能包含在可商购获得的原料中的载体或副产物。
如本文所用，术语“电荷密度”意思是在聚合物上的正电荷的数目与所述聚合物的分子量的比率。
如本文所用，术语“包含/包括”意思是可加入不影响最终结果的其它步骤和其它成分。该术语包括术语“由…组成”和“基本上由…组成”。本发明的组合物和方法/工艺可包含、由和基本上由本文所述的发明的要素和限制，以及本文所述的任何附加的或任选的成分、组分、步骤或限制组成。
如本文所用，术语“聚合物”包括无论是通过一种类型的单体聚合制成的还是通过两种（即，共聚物）或更多类型的单体制成的材料。
如本文所用，术语“适于施用到人的毛发上”意思是组合物或如此描述的它的组分用于在与人的毛发和头皮以及皮肤接触中使用是可接受的，而没有不适当的毒性、不相容性、不稳定性、变应性应答等。
如本文所用，术语“水溶性”意思是材料可溶解于本发明组合物中的水中。一般来讲，按所述水溶剂的重量计，材料在25℃下应以0.1%浓度，或者以1%，或者以5%，并且或者以15%溶解。
洗发剂组合物
如本文所用，术语“凝胶网络”是指包含至少一种脂肪醇，至少一种第二表面活性剂和水或其它适宜的溶剂的层状或泡状固体结晶相。在本发明的实施例中，该凝胶网络还与诸如阴离子表面活性剂的去污表面活性剂混合以形成洗发剂产品。在本发明的一个实施例中，阴离子表面活性剂为月桂基硫酸钠（SLS）。在洗发剂中使用SLS与凝胶网络的组合可导致配方困难。在体系中的SLS和月桂基聚氧乙烯醚-1硫酸钠（SLE1S）具有较高的填充系数。这可导致制备洗发剂产品更弹性，并且从而较不为消费者期望的，并且还可导致降低SLS的溶解度以及形成SLS结晶。
本发明的实施例平衡了SLS的溶解度，同时具有洗发剂可接受的流变特性或弹性。为了具有从瓶子中优良的分配，穿过手和毛发的优良的产品铺展，弹性是重要的。另外，很好地穿过毛发铺展的产品更快地起泡，并且更为消费者可接受的。本发明的洗发剂组合物的实施例，包含：（a）按所述洗发剂组合物的重量计，约9%至约17%的一种或多种阴离子表面活性剂，和按所述洗发剂组合物的重量计，小于约3.82%的月桂基聚氧乙烯醚n-硫酸钠，其中n>1；（b）按所述洗发剂组合物的重量计，约0.5%至约3%的选自两性、两性离子和非离子表面活性剂的辅助表面活性剂；（c）分散的凝胶网络相，包含：（i）按所述洗发剂组合物的重量计，至少约0.05%的一种或多种脂肪醇；（ii）按所述洗发剂组合物的重量计，至少约0.01%的一种或多种第二表面活性剂；和（iii）水；和（d）按所述洗发剂组合物的重量计，至少约20%的含水载体；其中所述洗发剂组合物具有如根据差示扫描量热法在介于约18℃至约30℃的峰值熔融转变温度测量的约0J/g至约0.2J/g的转变焓。这些组分的每一种，以及任选组分在下文中详细描述。在本发明的一个实施例中，n>1、2、3、4、5、6、7并且小于7、6、5、4、3、2以及它们的任何组合。
去污表面活性剂
本发明的洗发剂组合物包含一种或多种去污表面活性剂。去污表面活性剂组分包含在本发明的洗发剂组合物中以提供清洁性能。去污表面活性剂可选自阴离子去污表面活性剂、两性离子去污表面活性剂或两性去污表面活性剂或它们的组合。此类表面活性剂应与本文所述的组分物理和化学地相容，或不应另外不适当地损害产品稳定性、美观或性能。
用于在本文组合物中使用的适宜阴离子去污表面活性剂组分包括已知用于在毛发护理或其它个人护理洗发剂组合物中使用的那些。在一个实施例中，阴离子去污表面活性剂可为月桂基硫酸钠和月桂基聚氧乙烯醚n-硫酸钠的组合。在组合物中阴离子表面活性剂组分的浓度应足以提供期望的清洁和发泡性能，并且一般来讲按所述组合物的重量计，在约5%至约50%，或者约8%至约30%，或者约9%至约25%，并且或者约10%至约17%的范围内。
用于在本文组合物中使用的适宜的两性离子或两性去污表面活性剂包括已知用于在毛发护理或其它个人洗发剂组合物中使用的那些。此类两性去污表面活性剂的浓度在约0.5%至约20%，或者约1%至约10%的范围内。适宜的两性离子或两性表面活性剂的非限制性例子描述于美国专利5,104,646和5,106,609中。
适用于本文的附加阴离子表面活性剂包括式ROSO3M和RO(C2H4O)xSO3M的烷基和烷基醚硫酸盐，其中R为约8至约18个碳原子的烷基或烯基，x为1至10，并且M为水溶性阳离子，诸如铵、钠、钾和三乙醇胺阳离子或具有两个阴离子表面活性剂阴离子的二价镁离子盐。烷基醚硫酸盐可制备为环氧乙烷和具有约8至约24个碳原子的一元醇的缩合产物。醇可衍生自脂肪，诸如椰子油、棕榈油、棕榈仁油或牛脂，或可为合成的。
其它适宜的阴离子表面活性剂包括通式[R1-SO3M]的有机磺酸的水溶性盐。R1为具有13至17个碳原子，或者13至15个碳原子的直链脂族烃基。M为水溶性阳离子，诸如铵、钠、钾和三乙醇胺阳离子或具有两个阴离子表面活性剂阴离子的二价镁离子的盐。这些材料由SO2和O2与适宜链长的正链烷烃（C14-C17）产生，并且商业上作为链烷磺酸钠出售。
适用于本文的附加的阴离子表面活性剂的例子包括但不限于十二烷基硫酸铵、月桂基聚氧乙烯醚硫酸铵、月桂基硫酸三乙基胺、月桂基聚氧乙烯醚硫酸三乙基胺、月桂基硫酸三乙醇胺、月桂基聚氧乙烯醚硫酸三乙醇胺、月桂基硫酸单乙醇胺、月桂基聚氧乙烯醚硫酸单乙醇胺、月桂基硫酸二乙醇胺、月桂基聚氧乙烯醚硫酸二乙醇胺、月桂酸甘油单酯硫酸钠、月桂基硫酸钠、月桂基聚氧乙烯醚硫酸钠、月桂基聚氧乙烯醚硫酸钾、月桂基肌氨酸钠、月桂酰肌氨酸钠、肌氨酸月桂酯、椰油基肌氨酸、椰油基硫酸铵、十二烷酰基硫酸铵、椰油基硫酸钠、月桂酰硫酸钠、椰油基硫酸钾、月桂基硫酸钾、椰油基硫酸单乙醇胺、十三烷基聚氧乙烯醚硫酸钠、十三烷基硫酸钠、甲基月桂酰牛磺酸钠、甲基椰油基牛磺酸钠、月桂酰羟乙基磺酸钠、椰油基羟乙基磺酸钠、月桂基聚氧乙烯醚磺基琥珀酸钠、月桂基磺基琥珀酸钠、十三烷基苯磺酸钠、十二烷基苯磺酸钠、以及它们的混合物。
表面活性剂分布表
本发明的洗发剂组合物还可包含附加的表面活性剂以用于与本文所述的阴离子去污表面活性剂组分组合。适宜的附加表面活性剂包括阳离子表面活性剂和非离子表面活性剂。
适用于组合物中的其它阴离子、两性离子、两性、阳离子、非离子或任选的附加表面活性剂的非限制性例子描述于McCutcheon的Emulsifiers and Detergents，1989年刊，由M.C.Publishing Co.出版，和美国专利3,929,678、2,658,072、2,438,091和2,528,378中。
辅助表面活性剂
辅助表面活性剂为与十一烷基硫酸盐表面活性剂和任选阴离子表面活性剂混合的材料以增强泡沫体积和/或改进泡沫质感。通常，这些材料可选自多种结构家族，包括但不限于两性的、两性离子的、阳离子和非离子的。它们通常以1:20至1:4的重量比，并且或者以1:12至1:7的重量比与阴离子表面活性剂一起使用。
本发明的洗发剂组合物可包含按所述组合物的重量计，约0.5重量%至约10重量%，或者约0.5重量%至约5重量%，或者约0.5重量%至约3重量%，或者约0.5重量%至约2重量%，并且或者约0.5重量%至约1.75重量%的至少一种适宜的辅助表面活性剂。辅助表面活性剂可用来产生更快的泡沫，有利于更容易冲洗和/或缓解角质组织的粗糙。辅助表面活性剂还可有助于产生具有更期望的质感、体积和/或其它性能的泡沫。
适用于本文的两性表面活性剂包括但不限于脂族仲胺和叔胺衍生物，其中脂族基团可以为直链或支链的，并且其中脂族取代基中的一个取代基包含约8至约18个碳原子，并且一个包含阴离子水增溶的基团，如羧基、磺酸盐、硫酸盐、磷酸盐或膦酸酯。例子包括3-十二烷基氨基丙酸钠、3-十二烷基氨基丙烷磺酸钠、月桂基肌氨酸钠、N-烷基牛磺酸，诸如根据U.S.2,658,072中教导的，通过十二烷基胺与羟乙基磺酸钠反应制备的一个，N-高级烷基天冬氨酸，诸如根据U.S.2,438,091中教导生产的那些，以及描述于U.S.2,528,378中的产品、以及它们的混合物。在一个实施例中，两性表面活性剂可选自甜菜碱家族，诸如月桂酰两性醋酸盐。
适用于本文的两性离子表面活性剂包括但不限于脂族季铵、和锍化合物的衍生物，其中脂族基团可为直链或支链的，并且其中脂族取代基之一包含约8至约18个碳原子，并且一个取代基包含阴离子基团，如羧基、磺酸根、硫酸根、磷酸根或膦酸根。适用于本文的其它两性离子表面活性剂包括甜菜碱，包括高级烷基甜菜碱，诸如椰油二甲基羧甲基甜菜碱、椰油酰氨基丙基甜菜碱、椰油基甜菜碱、月桂基酰胺丙基甜菜碱、油烯基甜菜碱、月桂基二甲基羧甲基甜菜碱、月桂基二甲基α羧乙基甜菜碱、十六烷基二甲基羧甲基甜菜碱、月桂基双-(2-羟乙基)羧甲基甜菜碱、硬脂基双-(2-羟丙基)羧甲基甜菜碱、油烯基二甲基γ-羧丙基甜菜碱、月桂基双-(2-羟丙基)α-羧乙基甜菜碱、以及它们的混合物。磺基甜菜碱可包括椰油二甲基磺基丙基甜菜碱、硬脂基二甲基磺基丙基甜菜碱、月桂基二甲基磺乙基甜菜碱、月桂基双-(2-羟乙基)磺基丙基甜菜碱以及它们的混合物。其它适宜的两性表面活性剂包括酰氨基甜菜碱和酰氨基磺基甜菜碱，其中RCONH(CH2)3基团，其中R为C11-C17烷基，连接到甜菜碱的氮原子。
非离子辅助表面活性剂通常用于本发明的组合物中来增强泡沫体积或质感，包括水溶性材料，如月桂基二甲基氧化胺、椰油二甲基氧化胺、椰油酰氨基丙基氧化胺、月桂酰氨基丙基氧化胺等，或烷基多乙氧基化物，如月桂基聚氧乙烯醚-4至月桂基聚氧乙烯醚-7，以及水溶性组分，诸如椰油单乙醇酰胺、椰油二乙醇酰胺、月桂酰单乙醇酰胺、烷酰基异丙醇酰胺，和脂肪醇，如十六烷醇和油烯基醇和2-羟烷基甲基醚等。
还适宜作为本文辅助表面活性剂的材料包括1,2-烷基环氧化物、1,2-链烷二醇、支链或直链的烷基甘油基醚（如在EP1696023A1所公开的）、1,2-烷基环状碳酸酯和1,2-烷基环状亚硫酸盐，尤其是其中烷基以直链或支化的构型包含6至14个碳原子的那些。其它例子包括衍生自C10或C12α烯烃与乙二醇（如羟乙基-2-癸基醚、羟乙基-2-十二烷基醚）反应的烷基醚醇，如可根据U.S.5,741,948、U.S.5,994,595、U.S.6,346,509和U.S.6,417,408制备。
其它非离子的表面活性剂可选自葡萄糖酰胺、烷基多葡糖苷、蔗糖椰油酸酯、蔗糖月桂酸酯、链烷醇酰胺、乙氧基化的醇以及它们的混合物。在一个实施例中，非离子表面活性剂选自一羟基硬脂酸甘油酯、异硬脂基聚氧乙烯醚-2、十三烷基聚氧乙烯醚-3、羟基硬脂酸、丙二醇硬脂酸酯、PEG-2硬脂酸酯、一硬脂酸脱水山梨醇酯、甘油基月桂酸酯、月桂基聚氧乙烯醚-2、椰油酰胺单乙醇胺、月桂酰胺单乙醇胺、以及它们的混合物。
在一个具体实施例中，辅助表面活性剂选自椰油单乙醇酰胺、椰油酰氨基丙基甜菜碱、月桂酰氨基丙基甜菜碱、椰油基甜菜碱、月桂基甜菜碱、月桂基氧化胺、月桂基两性醋酸钠、烷基甘油基醚、烷基二甘油基醚、1,2-烷基环状亚硫酸盐、1,2-烷基环状碳酸盐、1,2-烷基环氧化物、烷基缩水甘油基醚和烷基-1,3-二氧杂环戊烷，其中烷基以直链或支化的构型包含6至14个碳原子；其中总碳含量为6至14个碳原子的直链或支化的1,2-链烷二醇、甲基-2-羟基癸基醚、羟乙基-2-十二烷基醚、羟乙基-2-癸基醚、以及它们的混合物。
阳离子表面活性剂可衍生自在制剂的pH下质子化的胺，如双羟乙基月桂基胺、月桂基二甲胺、月桂酰二甲基酰氨基丙基胺、椰油基酰胺丙基胺等。阳离子表面活性剂还可衍生自脂肪季铵盐，诸如月桂基三甲基氯化铵和月桂酰胺丙基三甲基氯化铵。
在一个实施例中，洗发剂组合物可包含两个或更多个相以制备多相个人护理组合物。一个相可包含传统的个人护理组分，诸如结构化的表面活性剂，并且本发明的多相个人护理组合物的第二相可包含有益相。
当存在时，有益相可为无水的并且可基本上不含水。有益相可包含小于约5重量%的水，或者小于3重量%的水，并且或者小于1重量%的水。有益相可基本上不含表面活性剂。有益相可包含小于约5重量%的表面活性剂，或者小于约3重量%的表面活性剂，并且或者小于约1重量%的表面活性剂。
有益相可包含疏水性保湿材料。有益相可由选自以下的组分构成：凡士林、羊毛脂、烃油，诸如矿物油，天然和合成蜡，诸如微晶蜡、石蜡、地蜡、羊毛脂蜡、羊毛脂醇、羊毛脂脂肪酸，聚乙烯、聚丁烯、聚癸烯和全氢化角鲨烯，挥发性的或非挥发性的有机基硅氧烷以及它们的衍生物，诸如聚二甲基硅氧烷、环甲基硅酮、烷基硅氧烷、聚甲基硅氧烷和甲基苯基聚硅氧烷，羊毛脂油、酯诸如羊毛脂酸异丙酯、乙酰化的羊毛脂、乙酰化的羊毛脂醇、亚油酸羊毛脂醇酯、蓖麻油酸羊毛脂醇酯、天然和合成甘油三酯，诸如蓖麻油、大豆油、向日葵籽油、马来酸化的大豆油、红花油、棉籽油、玉米油、胡桃油、花生油、橄榄油、鳕鱼肝油、杏仁油、鳄梨油、棕榈油和芝麻油、蓖麻油衍生物、蔗糖聚酯以及它们的组合。
在一个实施例中，有益相可包含疏水保湿材料。适用于具体地多相组合物中的疏水保湿材料可具有如由Vaughan在Cosmetics and Toiletries，第103卷中定义的约5(cal/cm3)1/2至约15(cal/cm3)1/2的Vaughan溶解度参数（“VSP”）。具有VSP值在约5至约15范围内的疏水保湿材料的非限制性例子包括以下这些：如在Solubility,Effects in Product, Package,Penetration and Preservation，C.D.Vaughan，Cosmetics and Toiletries，第103卷，1988年十月报道的环甲基硅酮5.92、角鲨烯6.03、凡士林7.33、棕榈酸异丙酯7.78、肉豆蔻酸异丙酯8.02、蓖麻油8.90、胆固醇9.55。
本发明的洗发剂组合物，当为多相形式时，可包含适于施用到诸如皮肤和/或毛发的角质组织的结构化的表面活性剂。在一个实施例中，包含结构化的表面活性剂的部分洗发剂组合物可包含至少约50%的各向异性相，并且在不同的实施例中，包含约50%至约90%的各向异性相。如在本文和US2007/0248562A1中所公开的，结构化的表面活性剂可包含阴离子、非离子、阳离子、两性离子、两性表面活性剂、皂、以及它们的组合与适宜的结构剂的组合。
烷基两性基乙酸盐为用于本文的多相组合物中适宜的结构化的表面活性剂，以用于改善的产品温和性和泡沫。最常用的烷基两性基乙酸盐为月桂酰两性基乙酸盐和椰油酰两性基乙酸盐。烷基两性基乙酸盐可包含一乙酸盐和二乙酸盐。在一些类型的烷基两性基乙酸盐中，二乙酸盐为杂质或非预期反应产物。然而，当以超过烷基两性基乙酸盐的15%的量存在时，二乙酸盐的存在可导致多种令人不快的组合物特性。
用于本文的适宜的非离子表面活性剂为选自葡萄糖酰胺、烷基多葡糖苷、蔗糖椰油酸酯、蔗糖月桂酸酯、链烷醇酰胺、乙氧基化的醇以及它们的混合物的那些。在一个实施例中，非离子表面活性剂选自一羟基硬脂酸甘油酯、异硬脂基聚氧乙烯醚-2、十三烷基聚氧乙烯醚-3、羟基硬脂酸、丙二醇硬脂酸酯、PEG-2硬脂酸酯、一硬脂酸脱水山梨醇酯、甘油基月桂酸酯、月桂基聚氧乙烯醚-2、椰油酰胺单乙醇胺、月桂酰胺单乙醇胺、以及它们的混合物。
结构化的表面活性剂可为离散的结构域形式，与非结构域视觉上不同。其中组合物包含结构化的相和非结构化的相两者时，结构域可使否则在组合物中乳化的高含量的护肤活性物质能够掺入。在具体实施例中，结构域为不透明的结构域。不透明的结构域可为层状相，并且可为产生层状凝胶网络的层状相。
在一个实施例中，结构化的表面活性剂为层状相的形式，其提供对剪切的抵抗，对悬浮颗粒和小滴足够的屈服，期望的流变特性和/或长期稳定性。层状相趋于具有对粘度改性剂最小化需求的粘度。
适宜的结构剂的非限制性例子描述于U.S.5,952,286中，并且包括不饱和的和/或支化的长链（C8-C24）液体脂肪酸或它们的酯衍生物；不饱和的和/或支化的长链液体醇或它们的醚衍生物、以及它们的混合物。结构化的表面活性剂还可包含短链饱和脂肪酸，诸如癸酸和辛酸。不愿被理论所束缚，据信脂肪酸的醇的不饱和的部分或脂肪酸的醇的支化的部分用来“扰乱”表面活性剂疏水性链并且诱导层状相的形成。适宜的液体脂肪酸的例子包括油酸、异硬脂酸、亚油酸、亚麻酸、蓖麻酸、反油酸、花生四烯酸、肉豆蔻脑酸、棕榈油酸、以及它们的混合物。适宜的酯衍生物的例子包括丙二醇异硬脂酸酯、丙二醇油酸酯、甘油基异硬脂酸酯、甘油基油酸酯、聚甘油基二异硬脂酸酯以及它们的混合物。醇的例子包括油醇和异硬脂醇。醚衍生物的例子包括异硬脂基聚氧乙烯醚或油基聚氧乙烯醚羧酸；或异硬脂基聚氧乙烯醚或油基聚氧乙烯醚醇。结构化试剂可定义为具有低于约25℃的熔点。
组合物可包含各向异性相和/或各向同性相两者。在具体实施例中，结构化的表面活性剂在组合物的视觉上不同的相中。
如果存在，组合物可包含流变改性剂，其中所述流变改性剂包括纤维素的流变改性剂、交联丙烯酸酯、交联马来酸酐共聚甲基乙烯基醚、疏水改性的缔合型聚合物或它们的混合物。
如果使用，电解质自身可添加到多相组合物中或它可以经由包括在原材料之一中的抗衡离子原位形成。电解质可包含阴离子，包括磷酸盐、氯化物、硫酸盐或柠檬酸盐，和阳离子，包括钠、铵、钾、镁或它们的混合物。电解质可为氯化钠、氯化铵、硫酸钠或硫酸铵。按所述结构化的表面活性剂组合物的重量计，电解质可以约0.1重量%至约15重量%，或者约1重量%至约6重量%，并且或者约3重量%至约6重量%的量被添加到多相组合物的结构化的表面活性剂相中。
在本发明的一个实施例中，个人护理组合物包含含有至少一种非离子表面活性剂和电解质的混合物的结构化的表面活性剂相。在另一个实施例中，表面活性剂相可包含表面活性剂、水、至少一种阴离子表面活性剂、电解质和至少一种链烷醇酰胺的混合物。
分散的凝胶网络相
本发明的洗发剂组合物包含含有一种或多种脂肪醇的分散的凝胶网络相。分散的凝胶网络相包含在本发明的洗发剂组合物中以提供调理有益效果。如本文所用，术语“凝胶网络”是指包含至少一种如下文详细说明的脂肪醇，至少一种如下文详细说明的第二表面活性剂和水或其它适宜的溶剂的层状或泡状的固体结晶相。层状或囊状相包含由包含脂肪醇和第二表面活性剂的第一层和交替的包含水和其它适宜的溶剂的第二层组成的双层。如本文所用，术语“固体结晶的”是指在凝胶网络中低于层的熔融转变温度的温度下形成的层状或囊状相结构，所述凝胶网络包含一种或多种脂肪醇，熔融转变温度为至少约30℃（即，略高于约室温）。熔融转变温度可通过差示扫描量热法测量，该方法在下文描述。
为了澄清之目的，涉及仅高于作为“固体结晶的”的定义的一部分的至少30℃的熔融转变温度，是与本发明的洗发剂组合物的分散的凝胶网络相的熔融转变温度不同的值。换句话讲，如上所述的层状或囊状相可为固体结晶的（即，至少30℃），但是此类固体结晶的层状或囊状相不一定为本发明的洗发剂组合物的分散的凝胶网络相。
包含例如脂肪醇的凝胶网络已在美容霜膏和毛发调理剂中被使用多年。然而，如果有的话，此类美容霜膏和毛发调理剂通常含有非常低含量的去污表面活性剂。因此，此类已知的产品不向毛发或皮肤提供清洁和调理的组合。
一般来讲，凝胶网络还由G.M.Eccleston，描述于“Functions of MixedEmulsifiers and Emulsifying Waxes in Dermatological Lotions and Creams”，Colloids and Surfaces A:Physiochem.和Eng.Aspects123-124卷（1997年）第169-182页中；并且由G.M Eccleston描述于“The Microstructure of Semisolid Creams”，PharmacyInternational，第7卷，第63-70页（1986年）中。在本发明的一个实施例中，分散的凝胶网络相为预成形的。如本文所用，术语“预成形的”意思是当添加到洗发剂组合物的其它组分中时，至少百分之五十的脂肪醇、第二表面活性剂和水或其它适宜的溶剂的混合物基本上为固体结晶相。
根据本发明的该实施例，本发明的凝胶网络组分作为单独的预混物被制备，它们在被冷却后，随后与去污表面活性剂和洗发剂组合物的其它组分混合。凝胶网络组分的制备在下文名称为制备洗发剂组合物的方法的章节以及例子中更详细地讨论。
冷却并预成形的凝胶网络组分随后被加入到包含去污表面活性剂组分的洗发剂组合物的其它组分中。不愿被理论所束缚，据信将冷的和预成形的凝胶网络组分与去污表面活性剂和洗发剂组合物的其它组分混合允许在最终洗发剂组合物中形成基本上平衡的层状分散体（“ELD”）。ELD为由预成形的凝胶网络组分与去污表面活性剂、水和其它可存在于洗发剂组合物中的任选组分，诸如盐基本上平衡造成的分散的层状或囊状相。在将预成形的凝胶网络组分与洗发剂组合物的其它组分混合时，发生该平衡，并且在制备后的约24小时内有效地完成。其中形成ELD的洗发剂组合物提供具有改善的润湿和干燥调理有益效果的毛发。另外，在一个混合步骤中，如果包含凝胶网络组分（即，与水混合的脂肪醇和第二表面活性剂）的组分作为单独的组分连同洗发剂组合物的其它组分被一起添加，并且不作为单独冷却的预成形的凝胶网络组分，那么不形成ELD。
为了说明之目的，如本文所用，术语“ELD”是指与短语“分散的凝胶网络相”相同的本发明的洗发剂组合物的组分。
在预混物中和以ELD形式的最终洗发剂组合物中存在的凝胶网络可通过本领域的技术人员已知的方法确认，诸如X射线分析、光学显微镜法、电子显微镜法和差示扫描量热法。差示扫描量热法的方法描述于下文。对于X射线分析方法，参见U.S.2006/0024256A1。
在本发明的一个实施例中，在洗发剂组合物（即，ELD）中分散的凝胶网络相的标度尺寸在约10nm至约500nm的范围内。在另一个实施例中，在洗发剂组合物中的分散的凝胶网络相的标度尺寸在约0.5μm至约10μm的范围内。在另一个实施例中，在洗发剂组合物中的分散的凝胶网络相的标度尺寸在约10μm至约150μm的范围内。
在洗发剂组合物中的分散的凝胶网络相的标度尺寸分布可用激光光散射技术，使用Horiba LA910型激光散射粒径分布分析仪（Horiba Instruments，Inc.IrvineCalifornia，USA）测量。在本发明的洗发剂组合物中的标度尺寸分布可通过将1.75g的洗发剂组合物与30mL的3%NH4Cl、20mL的2%Na2HPO4.7H2O和10mL的1%月桂基聚氧乙烯醚-7混合以形成混合物来测量。然后将该混合物搅拌5分钟。适合于所用的个别的Horiba仪器，量取在1至40mL范围内的样品，然后注射到Horiba仪器中，所述样品包含75mL的3%NH4Cl、50mL的2%Na2HPO4.7H2O和25mL的1%月桂基聚氧乙烯醚-7，直至Horiba仪器读数介于标度尺寸测量所需的88-92%T之间。一旦获得该数值，测量在通过Horiba仪器循环2分钟后进行以提供标度尺寸测量。后续的测量使用已在高于存在于洗发剂组合物中的所有脂肪材料的熔融转变温度加热的洗发剂组合物样品，使得凝胶网络组分熔融。后续的测量允许对在洗发剂中所有剩余的材料测定标度尺寸分布，然后所述标度尺寸分布可与第一样品的标度尺寸分布比较，并且有助于分析。
A.脂肪醇
本发明的凝胶网络组分包含至少一种脂肪醇。可选择单个的脂肪醇化合物或两种或更多种不同的脂肪醇化合物的组合。
适用于本发明的脂肪醇为具有约18至约70个碳原子的那些，并且在一个实施例中约18至约60个碳原子，在另一个实施例中约18至约50个碳原子，在另一个实施例中约18至约40个碳原子，并且在甚至另一个实施例中约18至约22个碳原子。这些脂肪醇可为直链或支链醇，并且可为饱和或不饱和的。适宜的脂肪醇的非限制性例子包括硬脂醇、二十烷醇、二十二醇、C21脂肪醇（1-二十一醇）、C23脂肪醇（1-二十三醇）、C24脂肪醇（二十四烷醇、1-二十四醇）、C26脂肪醇（1-二十六醇）、C28脂肪醇（1-二十八醇）、C30脂肪醇（1-三十烷醇）、C20-40醇（如，购自New Phase Technologies的Performacol350和425Alcohols）、C30-50醇（如，Performacol550Alcohol）、C40-60醇（如，Performacol700Alcohol）、以及它们的混合物。
包含一种或多种具有约18至约70个碳原子的脂肪醇的不同脂肪醇的混合物还可包含一些量的一种或多种脂肪醇，或具有小于约18个碳原子或大于约70个碳原子的其它脂族两亲物，并且仍然被认为是在本发明的范围内，前提条件是所得的分散的凝胶网络相具有至少约38℃的熔融转变温度。
适用于本发明的此类脂肪醇可具有天然或植物来源，或它们可具有合成来源。
本发明的洗发剂组合物按所述洗发剂组合物的重量计，以至少0.05%，或者约0.05%至约14%，或者约0.5%至约10%并且或者约1%至约8%的量包含脂肪醇作为分散的凝胶网络相的一部分。
在本发明的一个实施例中，在凝胶网络组分中脂肪醇与第二表面活性剂的重量比大于约1:9，或者约1:5至约100:1，并且或者约1:1至约50:1。
B.第二表面活性剂
本发明的凝胶网络组分还包含第二表面活性剂。如本文所用，“第二表面活性剂”是指当预混物与洗发剂组合物的其它组分分离时，与脂肪醇和水混合以形成本发明的凝胶网络的一种或多种表面活性剂。第二表面活性剂与洗发剂组合物的去污表面活性剂组分分离，并且是除了洗发剂组合物的去污表面活性剂组分以外的。然而，第二表面活性剂可为与选择用于上文所述的那个或那些去污表面活性剂组分相同或不同类型的表面活性剂或多种表面活性剂。
本发明的洗发剂组合物按所述洗发剂组合物的重量计，以约0.01%至约15%，或者约0.1%至约10%，并且或者约0.2%至约5%，包含第二表面活性剂作为预成形的分散的凝胶网络相的一部分。
适宜的第二表面活性剂包括阴离子表面活性剂、两性离子表面活性剂、两性表面活性剂、阳离子表面活性剂和非离子表面活性剂。第二表面活性剂可选自阴离子表面活性剂、阳离子表面活性剂和非离子表面活性剂、以及它们的混合物。对于适用于本发明的第二表面活性剂附加的讨论，参见U.S.2006/0024256A1。
另外，在本发明的一个实施例中，某些第二表面活性剂具有带有约16至约22个碳原子链长的疏水性尾基。对于此类第二表面活性剂，疏水性尾基可为烷基、烯基（包含至多3个双键）、烷基芳族或支化的烷基。在此类实施例中，第二表面活性剂可相对于脂肪醇以约1:5至约5:1的重量比存在于凝胶网络组分中。
上文详细说明类型的多于一种的表面活性剂可被用于本发明的第二表面活性剂中。
C.水或适宜的溶剂
本发明的凝胶网络组分还包含水或适宜的溶剂。水或适宜的溶剂和第二表面活性剂一起有助于脂肪醇的溶胀。继而这导致凝胶网络的形成和稳定性。如本文所用，术语“适宜的溶剂”是指在本发明的凝胶网络形成中，可被用来代替水或与水组合的任何溶剂。
当与脂肪醇和根据本发明的第二表面活性剂混合时，本发明的洗发剂组合物以适宜获得凝胶网络的量包含水或适宜的溶剂作为预成形的分散的凝胶网络相的一部分。
在一个实施例中，按所述洗发剂组合物的重量计，本发明的洗发剂组合物包含至少约0.05%的水或适宜的溶剂作为预成形的分散的凝胶网络相的一部分。
在本发明的另一个实施例中，洗发剂组合物以相对于脂肪醇至少约1:1的重量比的量，包含水或适宜的溶剂作为预成形的分散的凝胶网络相的一部分。
转变焓
根据本发明，洗发剂组合物具有如根据差示扫描量热法在介于约18℃至约30℃的峰值熔融转变温度测量的约0J/g至约0.2J/g的转变焓。在一个实施例中，洗发剂组合物具有如根据差示扫描量热法在介于约18℃至约30℃的峰值熔融转变温度测量的约0J/g至约0.1J/g的转变焓。
据信，在本发明的洗发剂组合物中，具有如根据差示扫描量热法在介于约18℃至约30℃的峰值熔融转变温度测量的约0J/g至约0.2J/g的转变焓有助于改善洗发剂组合物的物理稳定性，同时还递送改善的泡沫有益效果。
熔融转变温度可使用根据下列方法的差示扫描量热法获得。使用TA InstrumentsQ100DSC，将大约50mg的凝胶网络预混物或包含凝胶网络的最终洗发剂组合物置于不锈钢高容量的DSC盘中。将样品连同空的基准盘置于仪器中。样品使用下列条件/温度程序分析：氮吹扫，@4.00℃平衡，直至达到等温2.00分钟。以1.00℃/分钟的速率梯度升温至75.00℃。将每个样品一式两份进行分析。所得的DSC数据使用TA Instruments Universal AnalysisSoftware分析。
使用DSC测量熔融转变温度还由T.de Vringer等人描述于Colloid and PolymerScience，第265卷，第448-457页（1987年）；和H.M.Ribeiro等人的Intl.J.of CosmeticScience第26卷，第47-59页（2004年）。
含水载体
本发明的洗发剂组合物包含含水载体。通常，本发明的组合物为可倾倒的液体的形式（在环境条件下）。因此，组合物按所述组合物的重量计，以至少约，或者约20%至约95%，并且或者约60%至约85%的含量包含含水载体。含水载体可包括水或水和有机溶剂的可混溶的混合物。除了另外作为其它组分的微量成分附带地掺入到组合物中的，含水的载体还可包含具有最少或没有显著有机溶剂浓度的水。
附加的组分
本发明的组合物还可包含已知用于在毛发护理或个人护理产品中使用的一种或多种任选组分，前提条件是任选组分与本文所述的组分物理和化学地相容，或没有另外不适当地损害产品稳定性、美观或性能。按所述组合物的重量计，此类任选组分的各个浓度可在约0.001%至约10%的范围内。
用于在组合物中使用的任选组分的非限制性例子包括阳离子聚合物、调理剂（烃油、脂肪酯、硅氧烷）、去头皮屑剂、悬浮剂、粘度改性剂、染料、非挥发性的溶剂或稀释剂（水溶性和水不溶解的）、珠光助剂、泡沫促进剂、附加的表面活性剂或非离子辅助表面活性剂、灭虱药、pH调节剂、香料、防腐剂、螯合剂、蛋白、皮肤活性剂、防晒剂、紫外线吸收剂和维生素。
A.沉积助剂
本发明的洗发剂组合物可包含沉积助剂。包含沉积助剂以有效地增强凝胶网络组分的沉积。沉积助剂可包括增强凝胶网络从洗发剂沉积到毛发和/或头皮上的任何材料。
在洗发剂组合物中沉积助剂的浓度应足以有效地增强凝胶网络组分的沉积，并且按所述洗发剂组合物的重量计，在约0.05%至约5%，或者约0.075%至约2.5%，并且或者约0.1%至约1.0%的范围内。
在本发明的一个实施例中，沉积助剂为阳离子聚合物。在预期使用组合物的pH下，阳离子聚合物可具有至少约0.9meq/g，或者至少约1.2meq/g，或者至少约1.5meq/g，或者小于约7meq/g，并且或者小于约5meq/g的阳离子电荷密度。pH一般来讲将在约pH3至约pH9的范围内，或者介于约pH4和约pH8之间。聚合物的“阳离子电荷密度”，当那个术语被用于本文时，是指在聚合物上正电荷的数目与聚合物的分子量的比率。此类适宜的阳离子聚合物的平均分子量一般来讲将为介于约10,000和1千万之间，或者介于约50,000和约5百万之间，并且或者介于约100,000和约3百万之间。
用于在组合物中使用的适宜的阳离子聚合物包括多糖聚合物，诸如阳离子纤维素衍生物和阳离子淀粉衍生物，诸如羟乙基纤维素与三甲基铵取代的环氧化物反应的盐。其它适宜的阳离子聚合物包括阳离子瓜尔胶衍生物，诸如瓜尔胶羟丙基三甲基氯化铵。还适宜的阳离子聚合物包括半乳甘露聚糖聚合物衍生物，其以单体与单体计具有甘露糖与半乳糖大于2:1的比率，诸如肉桂胶羟丙基三甲基氯化铵。
B.分散的颗粒
本发明的组合物可包含分散的颗粒。用于本发明的颗粒可为无机的、合成或半合成来源。如果存在于本发明的组合物中，按所述组合物的重量计，分散的颗粒以约0.025%至约20%，或者约0.05%至约10%，或者约0.1%至约5%，或者约0.25%至约3%，并且或者约0.5%至约2%的量被掺入。
C.非离子聚合物
具有超过约1000的分子量的聚亚烷基二醇用于本文中。有用的是具有以下通式的那些：
其中R95选自H、甲基、以及它们的混合物。用于本文的聚乙二醇聚合物为PEG-2M（还已知为PolyoxN-10，并且其作为PEG-2,000购自Union Carbide）；PEG-5M（还已知为PolyoxN-35和PolyoxN-80，并且作为PEG-5,000和聚乙二醇300,000购自Union Carbide）；PEG-7M（还已知为PolyoxN-750，购自Union Carbide）；PEG-9M（还已知为PolyoxN-3333，购自Union Carbide）；和PEG-14M（还已知为PolyoxN-3000，购自Union Carbide）。
D.附加的调理剂
本发明的组合物还可包含除了分散的凝胶网络相以外的一种或多种调理剂。调理剂包括用来向毛发和/或皮肤提供具体的调理有益效果的材料。可用于本发明的组合物中的调理剂通常包括水不溶性的、水可分散的、非挥发性的、形成乳化的液体颗粒的液体。用于在组合物中使用的适宜的调理剂为一般来讲特征在于硅氧烷（如硅氧烷油、阳离子硅氧烷、硅氧烷树胶、高折射的硅氧烷和硅氧烷树脂）、有机调理油（如烃油、聚烯烃和脂肪酯）或它们的组合的那些调理剂，或在含水的表面活性剂基质中另外形成液体、分散的颗粒的那些调理剂。
在一个实施例中，本发明的洗发剂组合物还包含非挥发性硅油。对于不透明的组合物实施例，洗发剂组合物包含具有如在洗发剂组合物中测量的约1μm至约50μm粒度的非挥发性硅油。在本发明用于小颗粒应用至毛发的一个实施例中，洗发剂组合物包含具有如在洗发剂组合物中测量的约100nm至约1μm粒度的非挥发性硅油。对于基本上澄清的组合物实施例，洗发剂组合物包含具有如在洗发剂组合物中测量的小于约100nm粒度的非挥发性硅油。
当存在时，一种或多种调理剂为按所述组合物的重量计，约0.01%至约10%，或者约0.1%至约8%并且或者约0.2%至约4%的量。
调理剂可作为单独的组分存在于分散的凝胶网络相中或可被加入最终的洗发剂组合物中，使得它们主要存在于洗发剂的连续相中。
E.去头皮屑活性物质
本发明的组合物还可含有去头皮屑活性物质。去头皮屑活性物质的适宜的非限制性例子包括吡啶硫酮盐、唑、硫化硒、粒状硫、角质层分离剂、以及它们的混合物。此类去头皮屑活性物质应与组合物的组分物理和化学地相容，并且不应另外不适当地损害产品稳定性、美观或性能。
当存在于组合物中时，按所述组合物的重量计，去头皮屑活性物质以约0.01%至约5%，或者约0.1%至约3%，并且或者约0.3%至约2%的量被包括。
F.湿润剂
本发明的组合物可包含湿润剂。本文的润湿剂选自多元醇、水溶性烷氧基化的非离子聚合物、以及它们的混合物。当用于本文时，润湿剂按所述组合物的重量计，可以约0.1%至约20%，或者约0.5%至约5%的量存在。
G.悬浮剂
本发明的组合物还可在组合物中以分散的形式以有效地悬浮水不溶性材料或修饰组合物粘度的浓度包含悬浮剂。此类浓度按所述组合物的重量计，在约0.1%至约10%，或者约0.3%至约5.0%的范围内。
用于本文的悬浮剂包括结晶的悬浮剂，其可被分类成酰基衍生物、长链氧化胺、以及它们的混合物。这些悬浮剂描述于美国专利4,741,855中。这些悬浮剂可包括具有约16至约22个碳原子的脂肪酸的乙二醇酯。供选择的替代方案包括乙二醇硬脂酸酯，一硬脂酸酯和二硬脂酸酯两者，并且二硬脂酸酯包含小于约7%的一硬脂酸酯。
H.其它任选组分
本发明的组合物可包含其它任选组分。任选组分可作为单独的组分存在于分散的凝胶网络相中或可被加入最终洗发剂组合物中。
例如，本发明的组合物可含有水溶性和水不溶性的维生素，诸如维生素B1、B2、B6、B12、C、泛酸、泛基乙基醚、泛醇、生物素和它们的衍生物，以及维生素A、D、E和它们的衍生物。本发明的组合物还可含有水溶性的和水不溶性氨基酸，诸如天冬酰胺、丙氨酸、吲哚、谷氨酸和它们的盐、以及酪氨酸、色胺、赖氨酸、组氨酸和它们的盐。本发明的组合物还可包含用于毛发损失预防和毛发生长兴奋剂或试剂的物质。
任何其它适宜的任选组分也可被包含在本发明的组合物中，诸如通常用于给定产品类型中的那些成分。由Cosmetic,Toiletry,and Fragrance Association,Inc.,Washington,D.C.出版的CTFA Cosmetic Ingredient Handbook，第十版（2004年）描述了各种各样的可被添加到本文组合物中的非限制性材料。这些成分类别的例子包括但不限于：研磨剂、吸收剂、诸如香料和芳香剂、颜料、着色剂/染色剂、精油、皮肤感觉剂、收敛剂等（如丁香油、薄荷醇、樟脑、桉树油、丁子香酚、乳酸薄荷酯、金缕梅馏出液）的美容组分、抗痤疮剂、抗结块剂、消泡剂、抗微生物剂（如丁基氨基甲酸碘丙酯）、抗菌剂、抗真菌剂、抗氧化剂、基料、生物添加剂、缓冲剂、增量剂、螯合剂、化学添加剂、染色剂、美容收敛剂、化妆品杀虫剂、变性剂、药物收敛剂、外部止痛药、成膜剂或成膜材料，如用于帮助成膜性能和组合物亲和性的聚合物（如二十碳烯和乙烯基吡咯烷酮的共聚物）、遮光剂、pH调节剂、植物衍生物、植物提取物、植物组织提取物、植物种子提取物、植物油、植物性药材、植物提取物、防腐剂、推进剂、还原剂、皮脂控制剂、多价螯合剂、皮肤漂白和淡色剂、（如对苯二酚、曲酸、抗坏血酸、抗坏血酸基磷酸镁、抗坏血酸基葡糖苷、吡哆素）、酶、辅酶、皮肤调理剂（如润湿剂和吸留性试剂）、皮肤抚慰和/或康复剂和衍生物（如泛醇和衍生物，诸如乙基泛醇、芦荟、泛酸及其衍生物、尿囊素、红没药醇和甘草酸二钾盐）、皮肤处理剂（如维生素D化合物、一萜类化合物、二萜类化合物和三萜类化合物、β-紫罗兰醇、雪松醇）、增稠剂（包括一价盐或二价的盐，诸如氯化钠）以及维生素、它们的衍生物以及它们的组合。
当某些油溶性组分，诸如香料和芳香剂、氨基酸、水不溶性的维生素等存在于分散的凝胶网络相中时，或者通过将此类组分直接掺入到凝胶网络组分预混物中或分别地掺入到洗发剂组合物中，并且因此一些量的此类组分在平衡期间迁移到分散的凝胶网络相中，它们可有效地沉积在毛发和/或皮肤上。为了经由它们存在于分散的凝胶网络相中而获得非常有效的油溶性组分在毛发和/或皮肤上的沉积，可使用包含不小于约60%的具有约3或更高Clog P的成分的油溶性组分组合物。对于Clog P以及如何确定多种材料的它的值的另外的讨论参见例如美国专利5,849,310和5,500,154，以及EP1533364中。
粘度
根据本发明，具有在交变点的频率大于约2Hz下，洗发剂组合物具有介于约1,000cps至约30,000cps之间的零剪切粘度。在一个实施例中，具有在交变点频率大于约3Hz下，洗发剂组合物具有介于约5,000cps和约20,000cps之间的零剪切粘度。
据信，在具有在交变点的频率大于约2Hz下，具有介于约1,000cps和约30,000cps之间的零剪切粘度的本发明的洗发剂组合物允许洗发剂容易地分配并穿过毛发铺展。铺展和溶解还将增加泡沫产生的速度。
零剪切粘度可使用具有在0.01s-1下峰值保持30秒的AR2000流变仪获得。交变频率可通过从0.1至100Hz进行震荡频率扫描获得。交变点为G’和G”交叉的点。在交变处的频率为交变发生的频率。交叉影线平行板可被用来增加样品尺寸至1ml并且刺入样品以防止滑动。平行板的材料为丙烯酸以允许较低的几何形状惯性以有助于在较高的频率下具有不良的分辨率。
制备洗发剂组合物的方法
本发明的一个方面涉及制备本发明的洗发剂组合物的方法。制备洗发剂组合物的方法包括（a）在足以允许分配第二表面活性剂和水至脂肪醇的温度下混合脂肪醇、第二表面活性剂和水以形成预混物；（b）将预混物冷却至低于脂肪醇的链熔融温度以形成凝胶网络；（c）将凝胶网络加入一种或多种去污表面活性剂和含水载体中以形成包含具有至少约38℃熔融转变温度的分散的凝胶网络相的洗发剂组合物。
如上文所讨论，在本发明的一个实施例中，凝胶网络组分作为单独的预混物被制备，它们在被冷却后，随后与洗发剂组合物中的其它组分混合。更具体地，本发明的凝胶网络组分可通过加热脂肪醇、第二表面活性剂和水至约75℃至约90℃的范围内并且混合来制备。例如将混合物通过换热器，该混合物被冷却至约27℃至约35℃的范围。作为该冷却步骤的结果，至少约百分之五十的混合物的脂肪醇和第二表面活性剂结晶以形成结晶的凝胶网络。
制备凝胶网络组分供选择的方法包括超声处理和/或研磨脂肪醇、第二表面活性剂和水，同时加热这些组分以减少熔融的脂肪醇相的粒度。这导致脂肪醇相的表面积增加，这允许第二表面活性剂和水溶胀脂肪醇相。在制备凝胶网络上另一个适宜的变化包括首先加热并混合脂肪醇和第二表面活性剂，然后将那个混合物加入水中。
使用方法
本发明的组合物以常规的方式用于清洁和调理毛发或皮肤，包括头皮、面部和身体。一般来讲，本发明处理毛发或皮肤的方法包括向毛发或皮肤施用本发明的组合物。更具体地，将有效量的组合物施用到已用水润湿的毛发或皮肤，然后将组合物冲洗掉。此类有效量一般来讲在约1g至约50g，或者约1g至约20g的范围内。施用至毛发通常包括穿过毛发涂抹组合物使得大多数的或所有毛发与组合物接触。
处理毛发或皮肤的方法包括以下步骤：（a）用水润湿毛发或皮肤；（b）向毛发或皮肤施用有效量的洗发剂组合物，和（c）用水冲洗皮肤或毛发施用的区域。这些步骤可如期望的那样重复多次以实现期望的清洁和调理有益效果。
在一个实施例中，本发明的洗发剂组合物有利地用于处理受损的毛发。受损的毛发可包括选自以下的毛发：烫过的毛发、氧化着色的毛发和机械受损毛发。
在另一个实施例中，洗发剂组合物用来处理皮肤，诸如头皮、面部和身体。
本发明的洗发剂组合物可用作液体、固体、半固体、薄片、凝胶置于具有添加推进剂的加压容器中，或以泵式喷雾器形式使用。可选择产品的粘度以适应期望的形式。
非限制性实例
在下列实例中举例说明的洗发剂组合物示出了本发明的洗发剂组合物的具体实施例，但不旨在限制它们。可由技术人员进行其它修改而不脱离本发明的实质和范围。本发明洗发剂组合物的这些例证性实施例向毛发提供增强的调理有益效果。
在下列实例中举例说明的洗发剂组合物通过常规的制剂和混合方法来制备，它的实例在下文示出。除非另外指明，所有举例说明的量均以重量百分比列出，并且不包括微量组分材料，诸如稀释剂、防腐剂、有色溶液、假想成分、植物性药材等。除非另外指明，所有的百分比均以重量计。
凝胶网络预混物的制备
为了制备凝胶网络预混物，将水加热至约74℃，并且将脂肪醇和第二表面活性剂（如月桂基聚氧乙烯醚硫酸钠）加入其中。在混合后，该混合物通过研磨和换热器，在其中其被冷却至约32℃。作为该冷却步骤的结果，脂肪醇、第二表面活性剂和水形成结晶的凝胶网络。
凝胶网络预混物实例
凝胶网络预混物实例表
| 预混物 | % |
| 月桂基聚氧乙烯醚-1硫酸钠 | 10.00 |
| 硬脂醇 | 7.07 |
| 十六烷基醇 | 3.93 |
| 水 | 适量 |
最终洗发剂组合物的制备
下列实例示出了本发明。例证的组合物可通过常规的制剂和混合技术来制备。应当理解毛发护理制剂领域内的技术人员可进行本发明其它的修饰而不脱离本发明的实质和范围。除非另外指明，本文所有的份数、百分比和比率是按重量计的。一些组分可作为稀释液得自供应商。除非另外指明，给定的含量反映活性物质的重量%。一定量的香料和/或防腐剂也可包括在以下实例中。
洗发剂组合物实例1-74
| 实例 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
| 月桂基硫酸钠 | 7.19 | 7.42 | 6.96 | 6.96 | 5.60 | 5.82 | 6.51 | 7.19 |
| 月桂基聚氧乙烯醚-1硫酸钠 | 3.29 | 3.42 | 3.16 | 3.16 | 2.37 | 2.50 | 2.89 | 3.29 |
| 月桂基聚氧乙烯醚硫酸钠n>1 | 3.53 | 3.67 | 3.38 | 3.38 | 2.54 | 2.68 | 3.10 | 3.53 |
| 椰油酰氨基丙基甜菜碱 | 1.00 | 1.00 | 1.00 | 1.00 | 1.75 | 0.75 | 0.75 | 0.75 |
| 月桂基羟基磺基甜菜碱 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 椰油单乙醇酰胺 | 0.00 | 0.25 | 0.75 | 0.75 | 0.00 | 0.75 | 0.00 | 0.25 |
| 月桂基聚氧乙烯醚-4 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 硬脂醇 | 0.96 | 0.77 | 0.64 | 1.29 | 0.64 | 0.96 | 0.77 | 0.64 |
| 十六烷基醇 | 0.54 | 0.43 | 0.36 | 0.71 | 0.36 | 0.54 | 0.43 | 0.36 |
| 聚二甲基硅氧烷330M | 0.60 | 0.50 | 0.50 | 0.50 | 0.50 | 1.10 | 0.50 | 0.40 |
| 聚二甲基硅氧烷 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 瓜尔胶羟丙基三甲基氯化铵 | 0.00 | 0.10 | 0.00 | 0.10 | 0.10 | 0.10 | 0.00 | 0.00 |
| 乙二醇二硬脂酸酯 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 |
| 聚季铵-76 | 0.15 | 0.00 | 0.10 | 0.00 | 0.00 | 0.10 | 0.00 | 0.00 |
| 聚季铵-6 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.10 | 0.10 |
| 苯甲酸钠 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 |
| 硫酸镁 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 水 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 |
| 峰值熔融温度 | 25.96 | 26.31 | 25.17 | 28.64 | 27.38 | 36.92 | 24.25 | 25.67 |
| 焓J/g | 0.01 | 0.04 | 0.03 | 0.03 | 0.07 | 0.09 | 0.13 | 0.01 |
| 总阴离子 | 14 | 14.5 | 13.5 | 13.5 | 10.5 | 11 | 12.5 | 14 |
| 实例 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 |
| 月桂基硫酸钠 | 7.64 | 6.28 | 6.28 | 4.69 | 7.64 | 7.19 | 5.82 | 6.96 |
| 月桂基聚氧乙烯醚-1硫酸钠 | 3.55 | 2.76 | 2.76 | 1.84 | 3.55 | 3.29 | 2.50 | 3.16 |
| 月桂基聚氧乙烯醚硫酸钠n>1 | 3.81 | 2.96 | 2.96 | 1.97 | 3.81 | 3.53 | 2.68 | 3.38 |
| 椰油酰氨基丙基甜菜碱 | 1.50 | 2.00 | 0.75 | 3.00 | 0.00 | 1.00 | 0.75 | 1.00 |
| 月桂基羟基磺基甜菜碱 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 椰油单乙醇酰胺 | 0.50 | 0.85 | 0.00 | 0.00 | 1.00 | 0.00 | 0.75 | 0.75 |
| 月桂基聚氧乙烯醚-4 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 硬脂醇 | 0.64 | 0.64 | 0.96 | 1.16 | 0.64 | 0.90 | 0.96 | 0.96 |
| 十六烷基醇 | 0.36 | 0.36 | 0.54 | 0.64 | 0.36 | 0.50 | 0.54 | 0.54 |
| 聚二甲基硅氧烷330M | 0.20 | 0.20 | 1.00 | 0.50 | 0.60 | 0.80 | 1.10 | 0.80 |
| 聚二甲基硅氧烷 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 瓜尔胶羟丙基三甲基氯化铵 | 0.00 | 0.00 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 |
| 乙二醇二硬脂酸酯 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 |
| 聚季铵-76 | 0.10 | 0.10 | 0.00 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 |
| 聚季铵-6 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 苯甲酸钠 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 |
| 硫酸镁 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 水 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 |
| 峰值熔融温度 | 24.09 | 25.63 | 29.13 | . | 24.12 | 29.38 | 26.92 | 25.68 |
| 焓J/g | 0.004 | 0.02 | 0.17 | 0.00 | 0.02 | 0.04 | 0.09 | 0.03 |
| 总阴离子 | 15 | 12 | 12 | 8.5 | 15 | 14 | 11 | 13.5 |
| 实例 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 |
| 月桂基硫酸钠 | 5.82 | 6.96 | 6.28 | 7.64 | 7.60 | 6.45 | 8.12 | 8.54 |
| 月桂基聚氧乙烯醚-1硫酸钠 | 2.50 | 3.16 | 2.76 | 3.55 | 2.56 | 2.49 | 2.93 | 3.36 |
| 月桂基聚氧乙烯醚硫酸钠n>1 | 2.68 | 3.38 | 2.96 | 3.81 | 2.75 | 2.66 | 3.14 | 3.60 |
| 椰油酰氨基丙基甜菜碱 | 2.00 | 1.00 | 0.75 | 1.50 | 3.06 | 1.73 | 0.00 | 1.15 |
| 月桂基羟基磺基甜菜碱 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 椰油单乙醇酰胺 | 0.00 | 0.75 | 0.00 | 0.50 | 0.00 | 0.67 | 1.00 | 1.00 |
| 月桂基聚氧乙烯醚-4 | 0.00 | 0.00 | 0.00 | 0.00 | 0.33 | 0.67 | 0.67 | 0.00 |
| 硬脂醇 | 0.64 | 0.64 | 1.29 | 0.77 | 1.29 | 0.64 | 1.61 | 0.96 |
| 十六烷基醇 | 0.36 | 0.36 | 0.71 | 0.43 | 0.71 | 0.36 | 0.89 | 0.54 |
| 聚二甲基硅氧烷330M | 0.80 | 0.80 | 0.60 | 1.00 | 0.70 | 0.70 | 0.70 | 0.70 |
| 聚二甲基硅氧烷 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 瓜尔胶羟丙基三甲基氯化铵 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 |
| 乙二醇二硬脂酸酯 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 |
| 聚季铵-76 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 聚季铵-6 | 0.10 | 0.10 | 0.10 | 0.10 | 0.00 | 0.00 | 0.00 | 0.00 |
| 苯甲酸钠 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 |
| 硫酸镁 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 水 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 |
| 峰值熔融温度 | . | . | 25.24 | 24.66 | 26.96 | 24.95 | 26.46 | 25.78 |
| 焓J/g | 0.00 | 0.00 | 0.01 | 0.09 | 0.10 | 0.17 | 0.19 | 0.11 |
| 总阴离子 | 11 | 13.5 | 12 | 15 | 12.91 | 11.6 | 14.2 | 15.5 |
| 实例 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 |
| 月桂基硫酸钠 | 5.32 | 8.62 | 5.25 | 8.38 | 5.63 | 5.73 | 8.62 | 6.14 |
| 月桂基聚氧乙烯醚-1硫酸钠 | 1.78 | 3.32 | 1.82 | 3.12 | 1.63 | 1.58 | 3.32 | 2.63 |
| 月桂基聚氧乙烯醚硫酸钠n>1 | 1.90 | 3.56 | 1.95 | 3.35 | 1.74 | 1.69 | 3.56 | 2.82 |
| 椰油酰氨基丙基甜菜碱 | 0.00 | 0.00 | 0.70 | 0.00 | 0.00 | 1.54 | 2.32 | 2.48 |
| 月桂基羟基磺基甜菜碱 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 椰油单乙醇酰胺 | 1.00 | 0.00 | 0.67 | 0.33 | 0.67 | 0.67 | 0.67 | 1.00 |
| 月桂基聚氧乙烯醚-4 | 0.67 | 0.67 | 0.67 | 0.00 | 1.00 | 0.33 | 0.33 | 0.00 |
| 硬脂醇 | 0.64 | 0.96 | 0.64 | 1.29 | 1.29 | 1.61 | 0.64 | 0.64 |
| 十六烷基醇 | 0.36 | 0.54 | 0.36 | 0.71 | 0.71 | 0.89 | 0.36 | 0.36 |
| 聚二甲基硅氧烷330M | 0.70 | 0.70 | 0.70 | 0.70 | 0.70 | 0.70 | 0.70 | 0.70 |
| 聚二甲基硅氧烷 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 瓜尔胶羟丙基三甲基氯化铵 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 |
| 乙二醇二硬脂酸酯 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 |
| 聚季铵-76 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 聚季铵-6 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 苯甲酸钠 | 0.25 | 0.25 | 0.42 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 |
| 硫酸镁 | 0.00 | 0.00 | 0.00 | 0.50 | 0.00 | 0.00 | 0.00 | 0.00 |
| 水 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 |
| 峰值熔融温度 | 26.26 | 26.80 | 26.93 | 27.17 | . | . | 23.39 | 25.13 |
| 焓J/g | 0.16 | 0.12 | 0.16 | 0.13 | 0.00 | 0.00 | 0.03 | 0.08 |
| 总阴离子 | 9 | 15.5 | 9.02 | 14.85 | 9 | 9.01 | 15.5 | 11.6 |
| 实例 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 |
| 月桂基硫酸钠 | 5.37 | 5.57 | 5.40 | 5.32 | 6.69 | 8.54 | 6.68 | 6.83 |
| 月桂基聚氧乙烯醚-1硫酸钠 | 1.75 | 1.66 | 1.74 | 1.78 | 2.69 | 3.36 | 2.69 | 2.61 |
| 月桂基聚氧乙烯醚硫酸钠n>1 | 1.88 | 1.78 | 1.86 | 1.90 | 2.88 | 3.60 | 2.88 | 2.80 |
| 椰油酰氨基丙基甜菜碱 | 2.16 | 2.24 | 2.17 | 0.71 | 1.80 | 2.29 | 0.00 | 1.84 |
| 月桂基羟基磺基甜菜碱 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 椰油单乙醇酰胺 | 0.00 | 0.00 | 1.00 | 0.33 | 0.33 | 0.33 | 0.67 | 0.67 |
| 月桂基聚氧乙烯醚-4 | 1.00 | 0.00 | 0.00 | 0.33 | 0.33 | 0.00 | 0.00 | 0.67 |
| 硬脂醇 | 1.61 | 0.64 | 1.61 | 0.96 | 0.96 | 1.61 | 1.61 | 0.96 |
| 十六烷基醇 | 0.89 | 0.36 | 0.89 | 0.54 | 0.54 | 0.89 | 0.89 | 0.54 |
| 聚二甲基硅氧烷330M | 0.70 | 0.70 | 0.70 | 0.70 | 0.70 | 0.70 | 0.70 | 0.70 |
| 聚二甲基硅氧烷 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 瓜尔胶羟丙基三甲基氯化铵 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 |
| 乙二醇二硬脂酸酯 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 |
| 聚季铵-76 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 聚季铵-6 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 苯甲酸钠 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 |
| 硫酸镁 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 水 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 |
| 峰值熔融温度 | . | 27.72 | . | . | 27.88 | 27.86 | . | 27.11 |
| 焓J/g | 0.00 | 0.05 | 0.00 | 0.00 | 0.03 | 0.02 | 0.00 | 0.08 |
| 总阴离子 | 9 | 9 | 9 | 9 | 12.25 | 15.5 | 12.25 | 12.25 |
| 实例 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 |
| 月桂基硫酸钠 | 8.38 | 5.54 | 5.86 | 6.67 | 6.00 | 7.64 | 5.73 | 6.05 |
| 月桂基聚氧乙烯醚-1硫酸钠 | 3.12 | 2.30 | 2.14 | 2.88 | 2.50 | 2.64 | 1.58 | 2.58 |
| 月桂基聚氧乙烯醚硫酸钠n>1 | 3.35 | 2.46 | 2.30 | 3.09 | 2.68 | 2.83 | 1.69 | 2.76 |
| 椰油酰氨基丙基甜菜碱 | 1.12 | 0.00 | 0.79 | 0.90 | 0.00 | 3.08 | 1.54 | 2.44 |
| 月桂基羟基磺基甜菜碱 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 椰油单乙醇酰胺 | 0.00 | 0.00 | 1.00 | 0.33 | 1.00 | 1.00 | 0.00 | 0.00 |
| 月桂基聚氧乙烯醚-4 | 1.00 | 0.67 | 0.67 | 0.00 | 1.00 | 0.33 | 0.67 | 0.33 |
| 硬脂醇 | 0.96 | 0.96 | 1.61 | 0.96 | 1.61 | 1.29 | 1.61 | 1.61 |
| 十六烷基醇 | 0.54 | 0.54 | 0.89 | 0.54 | 0.89 | 0.71 | 0.89 | 0.89 |
| 聚二甲基硅氧烷330M | 0.70 | 0.70 | 0.70 | 0.70 | 0.70 | 0.70 | 0.70 | 0.70 |
| 聚二甲基硅氧烷 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 瓜尔胶羟丙基三甲基氯化铵 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 |
| 乙二醇二硬脂酸酯 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 |
| 聚季铵-76 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 聚季铵-6 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 苯甲酸钠 | 0.50 | 0.50 | 0.33 | 0.33 | 0.50 | 0.42 | 0.50 | 0.25 |
| 硫酸镁 | 0.00 | 0.17 | 0.33 | 0.33 | 0.00 | 0.50 | 0.50 | 0.50 |
| 水 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 |
| 峰值熔融温度 | 27.46 | . | . | 27.31 | . | . | . | . |
| 焓J/g | 0.07 | 0.00 | 0.00 | 0.07 | 0.00 | 0.00 | 0.00 | 0.00 |
| 总阴离子 | 14.85 | 10.3 | 10.3 | 12.63 | 11.17 | 13.11 | 9 | 11.39 |
| 实例 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 |
| 月桂基硫酸钠 | 5.12 | 5.16 | 5.73 | 8.23 | 6.24 | 5.59 | 6.96 | 6.96 |
| 月桂基聚氧乙烯醚-1硫酸钠 | 1.88 | 1.85 | 1.58 | 3.51 | 2.63 | 1.66 | 3.16 | 3.16 |
| 月桂基聚氧乙烯醚硫酸钠n>1 | 2.01 | 1.99 | 1.69 | 3.76 | 2.82 | 1.78 | 3.38 | 3.38 |
| 椰油酰氨基丙基甜菜碱 | 2.06 | 0.00 | 1.54 | 2.21 | 2.52 | 0.75 | 1.00 | 0.00 |
| 月桂基羟基磺基甜菜碱 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.00 |
| 椰油单乙醇酰胺 | 0.67 | 0.00 | 0.67 | 0.00 | 0.00 | 0.33 | 0.75 | 0.75 |
| 月桂基聚氧乙烯醚-4 | 1.00 | 0.67 | 1.00 | 0.00 | 0.33 | 0.00 | 0.00 | 0.00 |
| 硬脂醇 | 0.96 | 0.64 | 1.29 | 0.64 | 1.61 | 1.29 | 1.29 | 1.29 |
| 十六烷基醇 | 0.54 | 0.36 | 0.71 | 0.36 | 0.89 | 0.71 | 0.71 | 0.71 |
| 聚二甲基硅氧烷330M | 0.70 | 0.70 | 0.70 | 0.70 | 0.70 | 0.70 | 0.00 | 0.50 |
| 聚二甲基硅氧烷 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.80 | 0.00 |
| 瓜尔胶羟丙基三甲基氯化铵 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 | 0.10 |
| 乙二醇二硬脂酸酯 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 | 1.47 |
| 聚季铵-76 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 聚季铵-6 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| 苯甲酸钠 | 0.50 | 0.33 | 0.25 | 0.50 | 0.42 | 0.50 | 0.25 | 0.25 |
| 硫酸镁 | 0.17 | 0.50 | 0.17 | 0.50 | 0.00 | 0.33 | 0.00 | 0.00 |
| 水 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 | 适量 |
| 峰值熔融温度 | . | . | . | . | . | . | 24.51 | 28.6 |
| 焓J/g | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.07 | 0.08 |
| 总阴离子 | 9.01 | 9 | 9 | 15.5 | 11.69 | 9.03 | 13.5 | 13.5 |
| 成分 | 作为以下供应 |
| 聚季铵-76 | 聚季铵-7610%活性的，得自Rhodia |
| 聚季铵-6 | Mirapol100S，得自Rhodia |
| Jaguar C17 | Jaguar C17，得自Rhodia |
| Guar3196 | N-Hance3196得自Hercules Aqualon Div |
| C500 | Jaguar C500得自Rhodia |
| 聚二甲基硅氧烷330M | 聚二甲基硅氧烷330M，得自Momentive |
| 聚二甲基硅氧烷 | Besil DM500 |
本文所公开的量纲和值不可理解为严格限于所引用的精确值。相反，除非另外指明，每个这样的量纲旨在表示所述的值以及围绕该值功能上等同的范围。例如，所公开的量纲“40mm”旨在表示“约40mm”。
除非明确排除或换句话讲有所限制，本文所引用的每个文献包括任何交叉引用或相关的专利或专利申请，据此全文均以引用方式并入本文。对任何文献的引用均不是承认其为本文公开的或受权利要求书保护的任何发明的现有技术、或承认其独立地或以与任何其它一个或多个参考文献的任何组合提出、建议或公开任何此类发明。此外，当本文献中术语的任何含义或定义与以引用方式并入的文献中相同术语的任何含义或定义冲突时，应以本文献中赋予该术语的含义或定义为准。
尽管已用具体实施例举例说明和描述了本发明，但对于本领域中技术人员将显而易见的是，在不脱离本发明的实质和范围的情况下可作出多种其它的改变和变型。因此，所附权利要求书旨在涵盖本发明范围内的所有此类改变和变型。
Claims (15)
1.一种洗发剂组合物，包含：
a.预成形的分散的凝胶网络相，其包含：
i.按所述洗发剂组合物的重量计，至少0.05％的一种或多种脂肪醇；
ii.按所述洗发剂组合物的重量计，至少0.01％的一种或多种第二表面活性剂，其选自阴离子表面活性剂；和
iii.水；和
b.按所述洗发剂组合物的重量计，5％至50％的阴离子去污表面活性剂，其为月桂基硫酸钠与月桂基聚氧乙烯醚n-硫酸钠的组合；其中，按所述洗发剂组合物的重量计，具有n>1的月桂基聚氧乙烯醚n-硫酸钠的含量大于0且小于3.82％；月桂基聚氧乙烯醚-1硫酸钠的含量大于0.5％；
c.按所述洗发剂组合物的重量计，0.5％至3％的辅助表面活性剂，其选自两性表面活性剂和非离子表面活性剂；
d.按所述洗发剂组合物的重量计，至少20％的含水载体；其中所述洗发剂组合物具有根据差示扫描量热法在介于18℃至30℃的峰值熔融转变温度测量的0J/g至0.2J/g的转变焓。
2.根据权利要求1所述的洗发剂组合物，所述两性表面活性剂选自两性离子表面活性剂。
3.根据权利要求1所述的洗发剂组合物，其中所述洗发剂组合物包含按所述洗发剂组合物的重量计0.5％至2％的辅助表面活性剂，其选自两性表面活性剂和非离子表面活性剂。
4.根据权利要求3所述的洗发剂组合物，所述两性表面活性剂选自两性离子表面活性剂。
5.根据权利要求1-4中任一项所述的洗发剂组合物，其中所述洗发剂组合物包含按所述洗发剂组合物的重量计4％至9％的月桂基硫酸钠。
6.根据权利要求1-4中任一项所述的洗发剂组合物，其中所述洗发剂组合物包含按所述洗发剂组合物的重量计0.5％至5％的月桂基聚氧乙烯醚-1硫酸钠。
7.根据权利要求1-4中任一项所述的洗发剂组合物，其中所述预成形的分散的凝胶网络相包含按所述洗发剂组合物的重量计0.05％至14％的一种或多种脂肪醇。
8.根据权利要求1-4中任一项所述的洗发剂组合物，其中所述一种或多种脂肪醇选自十六烷基醇、硬脂醇、二十二醇、以及它们的混合物。
9.根据权利要求1-4中任一项所述的洗发剂组合物，其中所述预成形的分散的凝胶网络相包含按所述洗发剂组合物的重量计0.2％至5％的一种或多种第二表面活性剂。
10.根据权利要求1-4中任一项所述的洗发剂组合物，其中所述洗发剂组合物具有根据差示扫描量热法在介于18℃至30℃的峰值熔融转变温度测量的0J/g至0.1J/g的转变焓。
11.根据权利要求2或4所述的洗发剂组合物，其中所述两性离子表面活性剂为甜菜碱。
12.根据权利要求2或4所述的洗发剂组合物，其中所述两性离子表面活性剂为磺基甜菜碱。
13.根据权利要求1-4中任一项所述的洗发剂组合物，其中所述非离子表面活性剂为椰油单乙醇酰胺。
14.根据权利要求1-4中任一项所述的洗发剂组合物，其中所述洗发剂组合物具有：
a.介于1,000cps至30,000cps之间的零剪切粘度；和
b.在交变点处大于2Hz的频率。
15.一种用于制备根据前述权利要求中任一项所述的洗发剂组合物的方法，所述方法包括以下步骤：
a.在足以允许分配第二表面活性剂和水至脂肪醇的温度下混合脂肪醇、第二表面活性剂和水以形成预混物；
b.将预混物冷却低于脂肪醇的链熔融温度以形成凝胶网络；以及
c.将凝胶网络加入一种或多种去污表面活性剂和含水载体中以形成洗发剂组合物。
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161544769P | 2011-10-07 | 2011-10-07 | |
| US201161544750P | 2011-10-07 | 2011-10-07 | |
| US61/544,769 | 2011-10-07 | ||
| US61/544,750 | 2011-10-07 | ||
| US201261584515P | 2012-01-09 | 2012-01-09 | |
| US61/584,515 | 2012-01-09 | ||
| US201261597292P | 2012-02-10 | 2012-02-10 | |
| US61/597,292 | 2012-02-10 | ||
| PCT/US2012/058963 WO2013052802A2 (en) | 2011-10-07 | 2012-10-05 | Shampoo composition containing a gel network |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103842031A CN103842031A (zh) | 2014-06-04 |
| CN103842031B true CN103842031B (zh) | 2018-02-23 |
Family
ID=47045179
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201280048467.2A Active CN103842031B (zh) | 2011-10-07 | 2012-10-05 | 包含凝胶网络的洗发剂组合物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8653014B2 (zh) |
| EP (2) | EP3295931A1 (zh) |
| JP (1) | JP5930436B2 (zh) |
| CN (1) | CN103842031B (zh) |
| BR (1) | BR112014007727B1 (zh) |
| CA (1) | CA2850039C (zh) |
| ES (1) | ES2642364T3 (zh) |
| MX (1) | MX337661B (zh) |
| WO (1) | WO2013052802A2 (zh) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140356295A1 (en) | 2013-06-03 | 2014-12-04 | R.J. Reynolds Tobacco Company | Cosmetic compositions comprising tobacco seed-derived component |
| US20150011450A1 (en) * | 2013-07-03 | 2015-01-08 | The Procter & Gamble Company | Amphoteric Ter-Polymers For Use in Personal Care Compositions |
| MX2016009519A (es) * | 2014-01-23 | 2016-10-28 | Unilever Nv | Uso de una composicion acondicionadora de cabello para estilizar el cabello. |
| US10912719B2 (en) | 2014-10-20 | 2021-02-09 | The Procter And Gamble Company | Personal care composition and method of making |
| WO2016102505A1 (en) * | 2014-12-24 | 2016-06-30 | L'oreal | Cosmetic composition comprising at least one non-ionic and at least one anionic surfactant, at least one cationic and at least one amphoteric polymer and at least one silicone |
| CN107690328A (zh) * | 2015-04-23 | 2018-02-13 | 宝洁公司 | 低粘度毛发护理组合物 |
| BR112017022021B1 (pt) | 2015-04-23 | 2021-07-06 | The Procter & Gamble Company | Composição para tratamento dos cabelos |
| MX379907B (es) | 2016-03-03 | 2025-03-11 | Procter & Gamble | Composicion anticaspa en aerosol. |
| EP3468530A4 (en) | 2016-06-10 | 2020-03-11 | Clarity Cosmetics Inc. | NON-COMEDOGENOUS HAIR AND SCALP CARE FORMULATIONS AND METHOD OF USE |
| MX392137B (es) * | 2016-06-27 | 2025-03-21 | Procter & Gamble | Composición de champú que contiene una red de gel. |
| US10945935B2 (en) | 2016-06-27 | 2021-03-16 | The Procter And Gamble Company | Shampoo composition containing a gel network |
| MX382464B (es) | 2016-10-10 | 2025-03-13 | Procter & Gamble | Composiciones para el cuidado personal sustancialmente libres de surfactantes sulfatados y que contienen una red de gel |
| WO2018075847A1 (en) | 2016-10-21 | 2018-04-26 | The Procter & Gamble Company | Concentrated shampoo dosage of foam designating hair volume benefits |
| US10888505B2 (en) | 2016-10-21 | 2021-01-12 | The Procter And Gamble Company | Dosage of foam for delivering consumer desired dosage volume, surfactant amount, and scalp health agent amount in an optimal formulation space |
| US11154467B2 (en) | 2016-10-21 | 2021-10-26 | The Procter And Gamble Plaza | Concentrated shampoo dosage of foam designating hair conditioning benefits |
| US10653590B2 (en) | 2016-10-21 | 2020-05-19 | The Procter And Gamble Company | Concentrated shampoo dosage of foam for providing hair care benefits comprising an anionic/zwitterionic surfactant mixture |
| US10842720B2 (en) | 2016-10-21 | 2020-11-24 | The Procter And Gamble Company | Dosage of foam comprising an anionic/zwitterionic surfactant mixture |
| US20180110688A1 (en) | 2016-10-21 | 2018-04-26 | The Procter & Gamble Company | Concentrated Shampoo Dosage of Foam for Providing Hair Care Benefits |
| JP6952768B2 (ja) | 2016-10-21 | 2021-10-20 | ザ プロクター アンド ギャンブル カンパニーＴｈｅ Ｐｒｏｃｔｅｒ ＆ Ｇａｍｂｌｅ Ｃｏｍｐａｎｙ | 低粘度であり粘度低減剤を含む、安定なコンパクトシャンプー製品 |
| US11224567B2 (en) | 2017-06-06 | 2022-01-18 | The Procter And Gamble Company | Hair compositions comprising a cationic polymer/silicone mixture providing improved in-use wet feel |
| US11141370B2 (en) | 2017-06-06 | 2021-10-12 | The Procter And Gamble Company | Hair compositions comprising a cationic polymer mixture and providing improved in-use wet feel |
| US11679073B2 (en) | 2017-06-06 | 2023-06-20 | The Procter & Gamble Company | Hair compositions providing improved in-use wet feel |
| CN111278417A (zh) | 2017-10-10 | 2020-06-12 | 宝洁公司 | 含低无机盐的无硫酸盐澄清个人清洁组合物 |
| EP3694479A1 (en) | 2017-10-10 | 2020-08-19 | The Procter and Gamble Company | A method of treating hair or skin with a personal care composition in a foam form |
| WO2019074991A1 (en) | 2017-10-10 | 2019-04-18 | The Procter & Gamble Company | COMPACT SHAMPOO COMPOSITION COMPRISING ANIONIC AMINO ACID SURFACTANTS AND CATIONIC POLYMERS |
| EP3694480B1 (en) | 2017-10-10 | 2024-08-28 | The Procter & Gamble Company | Compact shampoo composition containing sulfate-free surfactants |
| JP7280265B2 (ja) | 2017-12-20 | 2023-05-23 | ザ プロクター アンド ギャンブル カンパニー | シリコーンポリマーを含有する透明なシャンプー組成物 |
| US20190216697A1 (en) | 2018-01-18 | 2019-07-18 | Nohbo,LLC | Hygiene product pod and methods of using same |
| EP3801443A1 (en) | 2018-06-05 | 2021-04-14 | The Procter & Gamble Company | Clear cleansing composition |
| JP2021528410A (ja) | 2018-06-29 | 2021-10-21 | ザ プロクター アンド ギャンブル カンパニーＴｈｅ Ｐｒｏｃｔｅｒ ＆ Ｇａｍｂｌｅ Ｃｏｍｐａｎｙ | 低界面活性剤エアゾール抗ふけ組成物 |
| US12226505B2 (en) | 2018-10-25 | 2025-02-18 | The Procter & Gamble Company | Compositions having enhanced deposition of surfactant-soluble anti-dandruff agents |
| WO2020122941A1 (en) * | 2018-12-14 | 2020-06-18 | Colgate-Palmolive Company | Silicone free emulsion-based personal care compositions and methods for the same |
| WO2020123484A1 (en) | 2018-12-14 | 2020-06-18 | The Procter & Gamble Company | Shampoo composition comprising sheet-like microcapsules |
| WO2020181395A1 (en) * | 2019-03-14 | 2020-09-17 | Crescita Therapeutics Inc. | Rinse-off compositions and uses thereof for delivery of active agents |
| US11896689B2 (en) | 2019-06-28 | 2024-02-13 | The Procter & Gamble Company | Method of making a clear personal care comprising microcapsules |
| JP7682846B2 (ja) * | 2019-07-09 | 2025-05-26 | ユニリーバー・アイピー・ホールディングス・ベスローテン・ヴェンノーツハップ | 抗フケ剤を含むヘアケア組成物 |
| US11883514B2 (en) | 2019-11-01 | 2024-01-30 | Colgate-Palmolive Company | Stable low pH personal care compositions and methods for the same |
| US11045397B2 (en) | 2019-11-06 | 2021-06-29 | Nohbo, LLC | Hygiene product pod and methods of using same |
| CN114746153A (zh) | 2019-12-06 | 2022-07-12 | 宝洁公司 | 具有增强头皮活性物质沉积的不含硫酸盐的组合物 |
| CN114945410A (zh) | 2020-01-13 | 2022-08-26 | 宝洁公司 | 包含库拉索芦荟的个人护理组合物 |
| CN216735268U (zh) | 2020-02-14 | 2022-06-14 | 宝洁公司 | 包装和泵式分配器 |
| EP4110474A1 (en) | 2020-02-27 | 2023-01-04 | The Procter & Gamble Company | Anti-dandruff compositions with sulfur having enhanced efficacy and aesthetics |
| WO2021251723A1 (ko) * | 2020-06-11 | 2021-12-16 | 코스맥스 주식회사 | 라멜라 구조를 갖는 컨디셔닝 샴푸 조성물 |
| KR102500882B1 (ko) * | 2020-06-11 | 2023-02-17 | 코스맥스 주식회사 | 라멜라 구조를 갖는 컨디셔닝 샴푸 조성물 |
| MX2023005963A (es) | 2020-12-04 | 2023-06-07 | Procter & Gamble | Composiciones para el cuidado del cabello que comprenden materiales de reduccion del mal olor. |
| US11633072B2 (en) | 2021-02-12 | 2023-04-25 | The Procter & Gamble Company | Multi-phase shampoo composition with an aesthetic design |
| US12053130B2 (en) | 2021-02-12 | 2024-08-06 | The Procter & Gamble Company | Container containing a shampoo composition with an aesthetic design formed by bubbles |
| EP4291149A1 (en) * | 2021-02-12 | 2023-12-20 | The Procter & Gamble Company | Container containing a shampoo composition with an aesthetic design formed by bubbles |
| US20240189203A1 (en) * | 2021-04-09 | 2024-06-13 | Colgate-Palmolive Company | Liquid Personal Care Compositions and Methods for the Same |
| US20220378684A1 (en) | 2021-05-14 | 2022-12-01 | The Procter & Gamble Company | Shampoo Compositions Containing a Sulfate-Free Surfactant System and Sclerotium Gum Thickener |
| US11986543B2 (en) | 2021-06-01 | 2024-05-21 | The Procter & Gamble Company | Rinse-off compositions with a surfactant system that is substantially free of sulfate-based surfactants |
| CN120112270A (zh) | 2022-10-31 | 2025-06-06 | 宝洁公司 | 含有生物表面活性剂的个人护理组合物 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101267797A (zh) * | 2005-09-16 | 2008-09-17 | 宝洁公司 | 包含凝胶网络的洗发剂 |
| CN101835459A (zh) * | 2007-10-26 | 2010-09-15 | 宝洁公司 | 包含十一烷基硫酸盐的个人护理组合物 |
| CN102014857A (zh) * | 2007-12-07 | 2011-04-13 | 宝洁公司 | 包含凝胶网络的洗发剂 |
Family Cites Families (160)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE406221A (zh) | 1933-11-15 | |||
| US2326733A (en) | 1941-05-07 | 1943-08-10 | Us Ind Alcohol Co | Accelerator of vulcanization |
| US2438091A (en) | 1943-09-06 | 1948-03-16 | American Cyanamid Co | Aspartic acid esters and their preparation |
| BE498391A (zh) | 1944-10-16 | |||
| BE498392A (zh) | 1945-11-09 | |||
| US2528378A (en) | 1947-09-20 | 1950-10-31 | John J Mccabe Jr | Metal salts of substituted quaternary hydroxy cycloimidinic acid metal alcoholates and process for preparation of same |
| US2658072A (en) | 1951-05-17 | 1953-11-03 | Monsanto Chemicals | Process of preparing amine sulfonates and products obtained thereof |
| US2694668A (en) | 1952-03-10 | 1954-11-16 | Abbott Lab | Liquid multiple vitamin preparation and process of preparing the same |
| US2798053A (en) | 1952-09-03 | 1957-07-02 | Goodrich Co B F | Carboxylic polymers |
| US2826551A (en) | 1954-01-04 | 1958-03-11 | Simoniz Co | Nontangling shampoo |
| US2809971A (en) | 1955-11-22 | 1957-10-15 | Olin Mathieson | Heavy-metal derivatives of 1-hydroxy-2-pyridinethiones and method of preparing same |
| US2786847A (en) | 1956-07-23 | 1957-03-26 | Reilly Tar & Chem Corp | 2-mercapto, alkanol pyridine-nu-oxides |
| US3152046A (en) | 1956-11-09 | 1964-10-06 | Kapral Ales Maria | Selenium disulfide dispersions |
| GB849433A (en) | 1957-08-22 | 1960-09-28 | Raymond Woolston | Hair washing preparations |
| US3155591A (en) | 1961-12-06 | 1964-11-03 | Witco Chemical Corp | Hair rinse compostions of polyoxypropylene quaternary ammonium compounds |
| US3236733A (en) | 1963-09-05 | 1966-02-22 | Vanderbilt Co R T | Method of combatting dandruff with pyridinethiones metal salts detergent compositions |
| US3332880A (en) | 1965-01-04 | 1967-07-25 | Procter & Gamble | Detergent composition |
| US3761418A (en) | 1967-09-27 | 1973-09-25 | Procter & Gamble | Detergent compositions containing particle deposition enhancing agents |
| US3590035A (en) | 1967-12-21 | 1971-06-29 | Procter & Gamble | Process for preparing pyridine n-oxide carbanion salts |
| US3773770A (en) | 1968-09-30 | 1973-11-20 | Procter & Gamble | Process for preparing pyridine n-oxide carbanion salts and derivatives thereof |
| US3589999A (en) | 1968-10-25 | 1971-06-29 | Ionics | Deionization process |
| US3852441A (en) | 1970-12-14 | 1974-12-03 | Procter & Gamble | Synergistic mixtures of diphenylbismuth acetate and the zinc salt of 1-hydroxy-2-pyridine thione effect as antibacterial and antifungal agents |
| US3940482A (en) | 1971-04-21 | 1976-02-24 | Colgate-Palmolive Company | Solubilization of the zinc salt of 1-hydroxy-2-pyridinethione |
| US3753196A (en) | 1971-10-05 | 1973-08-14 | Kulite Semiconductor Products | Transducers employing integral protective coatings and supports |
| US3958581A (en) | 1972-05-17 | 1976-05-25 | L'oreal | Cosmetic composition containing a cationic polymer and divalent metal salt for strengthening the hair |
| US3964500A (en) | 1973-12-26 | 1976-06-22 | Lever Brothers Company | Lusterizing shampoo containing a polysiloxane and a hair-bodying agent |
| US4422853A (en) | 1974-05-16 | 1983-12-27 | L'oreal | Hair dyeing compositions containing quaternized polymer |
| US4217914A (en) | 1974-05-16 | 1980-08-19 | L'oreal | Quaternized polymer for use as a cosmetic agent in cosmetic compositions for the hair and skin |
| US3959461A (en) | 1974-05-28 | 1976-05-25 | The United States Of America As Represented By The Secretary Of Agriculture | Hair cream rinse formulations containing quaternary ammonium salts |
| US3929678A (en) | 1974-08-01 | 1975-12-30 | Procter & Gamble | Detergent composition having enhanced particulate soil removal performance |
| US4089945A (en) | 1975-06-30 | 1978-05-16 | The Procter & Gamble Company | Antidandruff shampoos containing metallic cation complex to reduce in-use sulfide odor |
| AT365448B (de) | 1975-07-04 | 1982-01-11 | Oreal | Kosmetische zubereitung |
| US4197865A (en) | 1975-07-04 | 1980-04-15 | L'oreal | Treating hair with quaternized polymers |
| US4055655A (en) | 1975-07-21 | 1977-10-25 | National Research Laboratories | Complexes of heavy metal ions and polyfunctional organic ligands used as antimicrobial agents |
| US4152416A (en) | 1976-09-17 | 1979-05-01 | Marra Dorothea C | Aerosol antiperspirant compositions delivering astringent salt with low mistiness and dustiness |
| US4161526A (en) | 1978-07-20 | 1979-07-17 | Sterling Drug Inc. | Zinc salt prevention or removal of discoloration in pyrithione, pyrithione salt and dipyrithione compositions |
| US4507280A (en) | 1979-07-02 | 1985-03-26 | Clairol Incorporated | Hair conditioning composition and method for use |
| US4663158A (en) | 1979-07-02 | 1987-05-05 | Clairol Incorporated | Hair conditioning composition containing cationic polymer and amphoteric surfactant and method for use |
| NZ194560A (en) | 1979-08-10 | 1984-05-31 | Unilever Ltd | Deodorant compositions containing zinc carbonate |
| US4345080A (en) | 1980-02-07 | 1982-08-17 | The Procter & Gamble Company | Pyridinethione salts and hair care compositions |
| US4323683A (en) | 1980-02-07 | 1982-04-06 | The Procter & Gamble Company | Process for making pyridinethione salts |
| US4379753A (en) | 1980-02-07 | 1983-04-12 | The Procter & Gamble Company | Hair care compositions |
| US4387090A (en) | 1980-12-22 | 1983-06-07 | The Procter & Gamble Company | Hair conditioning compositions |
| FR2478467A1 (fr) | 1980-03-21 | 1981-09-25 | Fabre Sa Pierre | Nouvelles compositions utiles notamment dans le traitement et la prevention des pellicules et contenant des derives metalliques de l'acide thiobenzoique |
| US4529586A (en) | 1980-07-11 | 1985-07-16 | Clairol Incorporated | Hair conditioning composition and process |
| US4364387A (en) | 1980-12-18 | 1982-12-21 | Abbott Laboratories | Connecting device for medical liquid containers |
| US4470982A (en) | 1980-12-22 | 1984-09-11 | The Procter & Gamble Company | Shampoo compositions |
| ATE12730T1 (de) | 1981-10-21 | 1985-05-15 | Beecham Group Plc | Topische bakterizide zusammensetzungen. |
| US4565647B1 (en) | 1982-04-26 | 1994-04-05 | Procter & Gamble | Foaming surfactant compositions |
| EP0133914B1 (en) | 1983-07-06 | 1988-06-15 | Kao Corporation | Finely powdered polyvalent metal salts of 2-mercaptopyridine-n-oxide, method for producing the same, and antibacterial compositions comprising the same |
| CA1261276A (en) | 1984-11-09 | 1989-09-26 | Mark B. Grote | Shampoo compositions |
| USRE34584E (en) | 1984-11-09 | 1994-04-12 | The Procter & Gamble Company | Shampoo compositions |
| US4608183A (en) | 1985-01-14 | 1986-08-26 | Board Of Governors Of Wayne State University | Synergistic antimicrobial or biocidal mixtures including isothiazolones |
| US4788006A (en) | 1985-01-25 | 1988-11-29 | The Procter & Gamble Company | Shampoo compositions containing nonvolatile silicone and xanthan gum |
| US4666616A (en) | 1985-04-30 | 1987-05-19 | Board Of Governers Of Wayne State University | Synergistic antimicrobial or biocidal mixtures |
| US4704272A (en) | 1985-07-10 | 1987-11-03 | The Procter & Gamble Company | Shampoo compositions |
| GB2177108B (en) | 1985-07-10 | 1989-07-19 | Procter & Gamble | Shampoo compositions and method |
| US4686254A (en) | 1985-08-05 | 1987-08-11 | The B. F. Goodrich Company | Suspension composition for aqueous surfactant systems |
| HU200729B (en) | 1986-02-05 | 1990-08-28 | Mikrokemia Ipari Kisszoevetkez | Process for producing basic zinc carbonate |
| US5154847A (en) | 1986-06-16 | 1992-10-13 | Helene Curtis, Inc. | Antidandruff shampoo composition having improved suspension properties |
| US4834767A (en) | 1987-06-10 | 1989-05-30 | Gaf Corporation | Compositions used in permanent alteration of hair color |
| US4885107A (en) | 1987-05-08 | 1989-12-05 | The Procter & Gamble Company | Shampoo compositions |
| US4898585A (en) | 1988-05-18 | 1990-02-06 | Baxter Healthcare Corporation | Implantable patient-activated fluid delivery device with bolus injection port |
| US5186928A (en) | 1989-02-20 | 1993-02-16 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Shampoo composition |
| US5726137A (en) | 1989-06-21 | 1998-03-10 | Colgate-Palmolive Company | Low silicone hair conditioning shampoo and non-silicone hair conditioning/style control shampoo |
| US4997641A (en) | 1990-04-09 | 1991-03-05 | Colgate-Palmolive Company | Hair conditioning shampoo containing C6 -C10 alkyl sulfate or alkyl alkoxy sulfate |
| US5202048A (en) | 1989-06-30 | 1993-04-13 | The Procter & Gamble Company | Personal cleansing product with odor compatible bulky amine cationic polymer with reduced odor characteristics |
| US5104646A (en) | 1989-08-07 | 1992-04-14 | The Procter & Gamble Company | Vehicle systems for use in cosmetic compositions |
| US5106609A (en) | 1990-05-01 | 1992-04-21 | The Procter & Gamble Company | Vehicle systems for use in cosmetic compositions |
| US5114898A (en) | 1990-01-18 | 1992-05-19 | Board Of Trustees Operating Michigan State University | Layered double hydroxide sorbents for the removal of SOx from flue gas and other gas streams |
| US5057153A (en) | 1990-05-03 | 1991-10-15 | Olin Corporation | Paint containing high levels of a pyrithione salt plus a copper salt |
| US5034218A (en) | 1990-07-13 | 1991-07-23 | Helene Curtis, Inc. | Stable conditioning shampoo containing compatible anionic surfactant/cationic conditioning agent-non-volatile silicone emulsion |
| US5248445A (en) | 1992-01-30 | 1993-09-28 | Helene Curtis, Inc. | Stable conditioning shampoo containing fatty acid |
| IL104233A0 (en) | 1992-01-30 | 1993-05-13 | Curtis Helene Ind Inc | Stable conditioning shampoo containing fatty acid/fatty alcohol blend |
| US5696169A (en) | 1992-03-13 | 1997-12-09 | Otsuka Pharmaceutical Co., Ltd. | Antibacterial and antifungal activity method, therapeutic method of infectious diseases and preserving method of cosmetics |
| US5227156A (en) | 1992-04-14 | 1993-07-13 | Amway Corporation | Use of zinc compounds to stabilize a thiazolinone preservative in an anti-dandruff shampoo |
| ZA931613B (en) | 1992-04-15 | 1993-11-15 | Curtis Helene Ind Inc | Conditioning shampoo composition and method of preparing and using the same |
| US5576279A (en) | 1993-05-17 | 1996-11-19 | Helene Curtis, Inc. | Stable conditioning shampoo containing an anionic surfactant a fatty alcohol, and polyethyleneimine |
| CA2123532A1 (en) | 1993-05-17 | 1994-11-18 | Daniel R. Pyles | Stable conditioning shampoo containing an anionic surfactant, a fatty alcohol, a silicone conditioner and polyethyleneimine |
| WO1995001152A1 (en) | 1993-06-30 | 1995-01-12 | The Procter & Gamble Company | Conditioning shampoos containing polyvalent metal cations |
| EP0743846B1 (en) | 1994-02-02 | 2000-10-04 | The Procter & Gamble Company | Hair care compositions containing low melting point fatty alcohol and an ethylene oxide/propylene oxide polymer |
| US5462589A (en) | 1994-02-22 | 1995-10-31 | Mississippi Forest Products Laboratory | Synergistic wood preservative compositions |
| US5478501A (en) | 1994-04-07 | 1995-12-26 | The Andrew Jergens Company | Bathing composition containing coated cationic polymer |
| US5466425A (en) | 1994-07-08 | 1995-11-14 | Amphion International, Limited | Biological decontamination system |
| US5849310A (en) | 1994-10-20 | 1998-12-15 | The Procter & Gamble Company | Personal treatment compositions and/or cosmetic compositions containing enduring perfume |
| US5500154A (en) | 1994-10-20 | 1996-03-19 | The Procter & Gamble Company | Detergent compositions containing enduring perfume |
| US5614538A (en) | 1994-12-05 | 1997-03-25 | Olin Corporation | Synergistic antimicrobial composition containing pyrithione and alcohol |
| FR2728163A1 (fr) | 1994-12-20 | 1996-06-21 | Oreal | Composition cosmetique, dermatologique ou pharmaceutique stable contenant du disulfure de selenium et au moins un sel de zinc |
| US5562995A (en) | 1995-02-03 | 1996-10-08 | Olin Corporation | Discoloration prevention in pyrithione-containing coating compositions |
| US5939203A (en) | 1995-02-03 | 1999-08-17 | Arch Chemicals, Inc. | Discoloration prevention in pyrithione-containing coating compositions |
| DE19504914C1 (de) | 1995-02-15 | 1995-11-16 | Goldwell Gmbh | Haarwaschmittel |
| US5928671A (en) | 1995-04-25 | 1999-07-27 | Winthrop University Hospital | Method and composition for inhibiting bacteria |
| AU702870B2 (en) | 1995-06-08 | 1999-03-11 | Nippon Shokubai Co., Ltd. | Process for production of (poly)alkylene glycol monoalkyl ether |
| US5518774A (en) | 1995-06-26 | 1996-05-21 | Olin Corporation | In-can and dry coating antimicrobial |
| BR9609893A (pt) | 1995-08-07 | 1999-05-25 | Unilever Nv | Composição liquida de limpeza e processo para a indução de uma fase lamelar numa composição |
| FR2738482B1 (fr) | 1995-09-07 | 1997-10-24 | Oreal | Composition conditionnante et detergente a usage capillaire |
| WO1997014396A1 (en) | 1995-10-16 | 1997-04-24 | The Procter & Gamble Company | Conditioning shampoo compositions |
| DE69614706T2 (de) | 1995-10-16 | 2003-05-15 | The Procter & Gamble Company, Cincinnati | Polyalkylenglykol enthaltendes haarpflegeshampoo |
| WO1997014406A2 (en) | 1995-10-16 | 1997-04-24 | The Procter & Gamble Company | Conditioning shampoo compositions having improved stability |
| US5854319A (en) | 1995-11-30 | 1998-12-29 | Lambent Technologies Inc | Reactive silicone emulsions containing amino acids |
| US5674478A (en) | 1996-01-12 | 1997-10-07 | The Procter & Gamble Company | Hair conditioning compositions |
| US5750122A (en) | 1996-01-16 | 1998-05-12 | The Procter & Gamble Company | Compositions for treating hair or skin |
| US5874476A (en) | 1997-07-14 | 1999-02-23 | Rohm And Haas Company | Dihaloformaldoxime carbamates as antimicrobial agents |
| DE19646867C1 (de) | 1996-11-13 | 1997-12-04 | Henkel Kgaa | Kosmetische Zubereitungen |
| TW349106B (en) | 1996-12-06 | 1999-01-01 | Nippon Catalytic Chem Ind | Production process for (poly)alkylene glycol monoalkyl ether |
| DE19710149A1 (de) | 1997-03-12 | 1998-09-17 | Henkel Kgaa | Körperreinigungsmittel |
| DE19711417A1 (de) | 1997-03-19 | 1998-09-24 | Henkel Kgaa | Kosmetische Zubereitungen |
| US6017562A (en) | 1997-04-28 | 2000-01-25 | Arch Chemicals, Inc. | Non-spherical and non-platelet crystalline forms of pyrithione salts |
| US20020012646A1 (en) | 1997-05-06 | 2002-01-31 | Royce Douglas Allan | Shampoo compositions with cationic polymers |
| US5880076A (en) | 1997-08-04 | 1999-03-09 | Lever Brothers Company, Division Of Conopco, Inc. | Compositions comprising glycacarbamate and glycaurea compounds |
| US5939059A (en) | 1997-08-13 | 1999-08-17 | Akzo Nobel Nv | Hair conditioner and 2 in 1 conditioning shampoo |
| US6346509B1 (en) | 1997-12-05 | 2002-02-12 | Nippon Shokubai Co., Ltd. | Higher secondary alcohol alkoxylate compound composition, method for production thereof, and detergent and emulsifier using the composition |
| GB9807271D0 (en) | 1998-04-03 | 1998-06-03 | Unilever Plc | Hair treatment compositions |
| GB9811754D0 (en) | 1998-06-01 | 1998-07-29 | Unilever Plc | Hair treatment compositions |
| FR2781368B1 (fr) | 1998-07-27 | 2000-09-01 | Oreal | Composition contenant un agent opacifiant ou nacrant et au moins un alcool gras |
| GB9824024D0 (en) | 1998-11-03 | 1998-12-30 | Unilever Plc | Shampoo compositions |
| US6034043A (en) | 1999-04-20 | 2000-03-07 | Lever Brothers Company, Division Of Conopco, Inc. | Mild antimicrobial liquid cleansing formulations comprising polyvalent cation or cations for improving an antimicrobial effectiveness |
| US6451300B1 (en) * | 1999-05-03 | 2002-09-17 | The Procter & Gamble Company | Anti-dandruff and conditioning shampoos containing polyalkylene glycols and cationic polymers |
| US6495538B2 (en) | 1999-06-23 | 2002-12-17 | Zinc Therapeutics, Canada Inc. | Zinc ionophores as therapeutic agents |
| MXPA01013447A (es) | 1999-06-25 | 2002-12-05 | Arch Chem Inc | Biocidas de piritiona mejorados por iones de plata, cobre o zinc. |
| US20020169283A1 (en) | 1999-10-21 | 2002-11-14 | Lu Peter S. | Clasp-7 transmembrane protein |
| JP4024446B2 (ja) * | 1999-12-20 | 2007-12-19 | ライオン株式会社 | 液体洗浄剤組成物 |
| JP4558122B2 (ja) | 2000-01-14 | 2010-10-06 | 株式会社資生堂 | 抗菌防カビ剤及び抗菌防カビ組成物 |
| DE10005162A1 (de) | 2000-02-08 | 2001-08-09 | Henkel Kgaa | Kosmetisches Mittel |
| WO2001078657A1 (en) | 2000-04-12 | 2001-10-25 | P&G - Clairol, Inc. | Cationic emulsifier-enhanced liquid crystal gel network based skin care moisturizing compositions |
| IT1318571B1 (it) | 2000-06-09 | 2003-08-27 | Farmaka Srl | Composizioni cosmetiche per la cura del cuoio capelluto e dei capelli. |
| US20030185779A1 (en) | 2000-09-08 | 2003-10-02 | The Procter & Gamble Company | Hair care kits and heating devices for warming hair care compositions |
| US6608011B2 (en) | 2001-06-11 | 2003-08-19 | Colgate-Palmolive Company | Shampoos with behenyl-alcohol |
| DE10129034A1 (de) | 2001-06-15 | 2002-12-19 | Cognis Deutschland Gmbh | Verdicker für Haarpflegemittel |
| DE10150727A1 (de) | 2001-10-13 | 2003-04-17 | Cognis Deutschland Gmbh | Kosmetische und/oder pharmazeutische Zubereitungen |
| DE10150730A1 (de) | 2001-10-13 | 2003-04-17 | Cognis Deutschland Gmbh | Kosmetische und/oder pharmazeutische Zubereitungen |
| DE10150728A1 (de) | 2001-10-13 | 2003-04-17 | Cognis Deutschland Gmbh | Kosmetische und/oder pharmazeutische Zubereitungen |
| US6797683B2 (en) | 2002-03-04 | 2004-09-28 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Ordered liquid crystalline cleansing composition with benefit agent particles |
| US6812192B2 (en) | 2002-03-28 | 2004-11-02 | L'oreal S.A. | Foaming cosmetic compositions, uses for cleansing or make-up removal |
| JP4376634B2 (ja) | 2002-03-29 | 2009-12-02 | 株式会社資生堂 | 複合粉体及びそれを含む化粧料 |
| EP1496899B1 (en) | 2002-04-22 | 2021-06-23 | The Procter & Gamble Company | Use of materials having zinc ionophoric behavior |
| US8119168B2 (en) | 2002-04-22 | 2012-02-21 | The Procter & Gamble Company | Personal care compositions comprising a zinc containing material in an aqueous surfactant composition |
| AU2003273285B2 (en) | 2002-06-04 | 2007-01-25 | The Procter & Gamble Company | Shampoo containing a gel network |
| US20050202984A1 (en) | 2003-03-18 | 2005-09-15 | Schwartz James R. | Composition comprising zinc-containing layered material with a high relative zinc lability |
| US8361448B2 (en) * | 2002-06-04 | 2013-01-29 | The Procter & Gamble Company | Shampoo containing a gel network |
| US8367048B2 (en) | 2002-06-04 | 2013-02-05 | The Procter & Gamble Company | Shampoo containing a gel network |
| US8491877B2 (en) | 2003-03-18 | 2013-07-23 | The Procter & Gamble Company | Composition comprising zinc-containing layered material with a high relative zinc lability |
| US8361450B2 (en) | 2002-06-04 | 2013-01-29 | The Procter & Gamble Company | Shampoo containing a gel network and a non-guar galactomannan polymer derivative |
| US9381382B2 (en) | 2002-06-04 | 2016-07-05 | The Procter & Gamble Company | Composition comprising a particulate zinc material, a pyrithione or a polyvalent metal salt of a pyrithione and a gel network |
| US9381148B2 (en) | 2003-03-18 | 2016-07-05 | The Procter & Gamble Company | Composition comprising particulate zinc material with a high relative zinc lability |
| US8349302B2 (en) * | 2002-06-04 | 2013-01-08 | The Procter & Gamble Company | Shampoo containing a gel network and a non-guar galactomannan polymer derivative |
| JP3929967B2 (ja) * | 2002-12-10 | 2007-06-13 | 花王株式会社 | 水性毛髪洗浄剤 |
| EP1603515A1 (en) | 2003-03-12 | 2005-12-14 | Unilever N.V. | Method to prepare personal care composition from a concentrate |
| US20040191331A1 (en) | 2003-03-18 | 2004-09-30 | The Procter & Gamble Company | Composition comprising particulate zinc materials having a defined crystallite size |
| US6774096B1 (en) | 2003-10-09 | 2004-08-10 | Colgate-Palmolive Co. | Zinc oxide containing surfactant solution |
| US20050143268A1 (en) | 2003-11-14 | 2005-06-30 | The Procter & Gamble Company | Personal care composition containing a cleansing phase and a benefit phase |
| MXPA04011520A (es) | 2003-11-20 | 2005-08-16 | Int Flavors & Fragrances Inc | Materiales encapsulados. |
| JP2005187342A (ja) | 2003-12-24 | 2005-07-14 | Lion Corp | シャンプー組成物 |
| JP2008511722A (ja) | 2004-08-31 | 2008-04-17 | ハーキュリーズ・インコーポレーテッド | 悪臭を減少させた低分子量のカチオン性ポリガラクトマンナン |
| JP2006182728A (ja) * | 2004-12-28 | 2006-07-13 | Kao Corp | 水性毛髪洗浄剤 |
| KR101222646B1 (ko) | 2005-02-28 | 2013-01-16 | 가오 가부시키가이샤 | 계면활성제 조성물 |
| US8153144B2 (en) | 2006-02-28 | 2012-04-10 | The Proctor & Gamble Company | Stable multiphase composition comprising alkylamphoacetate |
| CA2667555A1 (en) * | 2006-11-08 | 2008-05-15 | Unilever Plc | Conditioning shampoo compositions |
| WO2010043481A1 (en) * | 2008-10-16 | 2010-04-22 | Unilever Plc | Composition |
| KR102449509B1 (ko) | 2016-01-05 | 2022-09-29 | 엘지전자 주식회사 | 의류처리장치용 리프터 |
-
2012
- 2012-10-05 CA CA2850039A patent/CA2850039C/en active Active
- 2012-10-05 JP JP2014534768A patent/JP5930436B2/ja active Active
- 2012-10-05 BR BR112014007727-4A patent/BR112014007727B1/pt active IP Right Grant
- 2012-10-05 MX MX2014004154A patent/MX337661B/es active IP Right Grant
- 2012-10-05 EP EP17175854.3A patent/EP3295931A1/en not_active Withdrawn
- 2012-10-05 CN CN201280048467.2A patent/CN103842031B/zh active Active
- 2012-10-05 WO PCT/US2012/058963 patent/WO2013052802A2/en active Application Filing
- 2012-10-05 ES ES12775111.3T patent/ES2642364T3/es active Active
- 2012-10-05 EP EP12775111.3A patent/EP2763748B1/en active Active
- 2012-10-05 US US13/646,227 patent/US8653014B2/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101267797A (zh) * | 2005-09-16 | 2008-09-17 | 宝洁公司 | 包含凝胶网络的洗发剂 |
| CN101267796A (zh) * | 2005-09-16 | 2008-09-17 | 宝洁公司 | 包含凝胶网络的洗发剂 |
| CN101835459A (zh) * | 2007-10-26 | 2010-09-15 | 宝洁公司 | 包含十一烷基硫酸盐的个人护理组合物 |
| CN102014857A (zh) * | 2007-12-07 | 2011-04-13 | 宝洁公司 | 包含凝胶网络的洗发剂 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2763748A2 (en) | 2014-08-13 |
| BR112014007727A2 (pt) | 2017-04-04 |
| EP3295931A1 (en) | 2018-03-21 |
| JP5930436B2 (ja) | 2016-06-08 |
| WO2013052802A3 (en) | 2013-07-11 |
| EP2763748B1 (en) | 2017-07-26 |
| CA2850039A1 (en) | 2013-04-11 |
| CN103842031A (zh) | 2014-06-04 |
| MX337661B (es) | 2016-03-14 |
| US20130090279A1 (en) | 2013-04-11 |
| BR112014007727B1 (pt) | 2019-04-30 |
| ES2642364T3 (es) | 2017-11-16 |
| WO2013052802A2 (en) | 2013-04-11 |
| JP2014528455A (ja) | 2014-10-27 |
| MX2014004154A (es) | 2014-07-28 |
| CA2850039C (en) | 2017-03-07 |
| US8653014B2 (en) | 2014-02-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103842031B (zh) | 包含凝胶网络的洗发剂组合物 | |
| US6407044B2 (en) | Aerosol personal cleansing emulsion compositions which contain low vapor pressure propellants | |
| US5869070A (en) | Shelf stable skin cleansing liquid with gel forming polymer and lipid | |
| US5674511A (en) | Shelf stable skin cleansing liquid with gel forming polymer, lipid and crystalline ethylene glycol fatty acid ester | |
| CN1780602B (zh) | 由清洁相和包含油包水乳液的独立有益相组成的条纹状液体个人清洁组合物 | |
| US6277797B1 (en) | Dispersed amorphous silica as oil in water stabilizer for skin cleansing liquid composition | |
| US10945935B2 (en) | Shampoo composition containing a gel network | |
| CN109310586A (zh) | 包含凝胶网络的洗发剂组合物 | |
| WO2005105033A1 (en) | Personal care compositions that deposit hydrophilic benefit agents | |
| EP1051153A1 (en) | Moisturizing personal cleansing compositions with improved lipid deposition | |
| WO1999038489A1 (en) | Liquid personal cleansing emulsion compositions which contain a weighting oil | |
| US20050238595A1 (en) | Personal care compositions that deposit sunless tanning benefit agents | |
| CA2524306A1 (en) | Personal care compositions containing a silicone elastomer and a dispersed oil phase | |
| JP2017036261A (ja) | ミコナゾール硝酸塩含有組成物 | |
| HK1196579A (zh) | 包含凝膠網絡的洗髮劑組合物 | |
| HK1196579B (zh) | 包含凝膠網絡的洗髮劑組合物 | |
| HK1121960A1 (zh) | 包含凝膠網絡的洗髮劑 | |
| HK1121960B (zh) | 包含凝膠網絡的洗髮劑 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1196579 Country of ref document: HK |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: GR Ref document number: 1196579 Country of ref document: HK |