CN103479754B - Hypotensive drug and preparation method thereof - Google Patents
Hypotensive drug and preparation method thereof Download PDFInfo
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- CN103479754B CN103479754B CN201310484966.2A CN201310484966A CN103479754B CN 103479754 B CN103479754 B CN 103479754B CN 201310484966 A CN201310484966 A CN 201310484966A CN 103479754 B CN103479754 B CN 103479754B
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Abstract
The invention provides a hypotensive drug and a preparation method thereof. The hypotensive drug comprises the following components in parts by weight: 200-400 parts of kudzuvine root, 200-400 parts of red sage root, 80-150 parts of ligusticum wallichii, 200-400 parts of astragalus, 100-250 parts of cassia seed, 200-400 parts of crataegus pinnatifida, 100-250 parts of prunella vulgaris, 100-250 parts of rhodiola rosea, 30-70 parts of leech, 200-400 parts of codonopsis pilosula, 30-70 parts of ganoderma lucidum, 30-70 parts of ginseng or American ginseng, and 80-150 parts of gynostemma pentaphylla. The preparation method comprises the steps of weighing raw materials; preparing powder from each raw material; mixing all raw materials to obtain a first mixture; preparing pills from the first mixture; baking the pills; packaging. The hypotensive drug can play a good blood pressure reduction effect, is small in side effect, and has the effects of calming and preventing angiosclerosis.
Description
Technical field
The present invention relates to field of medicaments, in particular to a kind of depressor and preparation method thereof.
Background technology
Along with the raising of people's living standard, " hypertension " is jeopardizing the healthy of more and more people, field of medicaments also arises at the historic moment a collection of " blood pressure lowering " medicine, but these medicines are generally Western medicine, although instant effect, but after long-term taking, the one-tenth branch in medicine produces more side effect, such as: blood pressure can fall, but anti-on liver-yang, deficiecny of liver-YIN, emotional lability, agitation, headache and dizziness, cough, stomachache, urine volume too much, insomnia, promote being short of power of blood.
Summary of the invention
The object of the present invention is to provide a kind of depressor and preparation method thereof, to solve the above problems.
Embodiments provide a kind of depressor: its raw material comprises: in mass fraction, 200-400 part Radix Puerariae, 200-400 part Radix Salviae Miltiorrhizae, 80-150 part Rhizoma Chuanxiong, 200-400 part Radix Astragali, 100-250 part Semen Cassiae, 200-400 part Fructus Crataegi, 100-250 part Spica Prunellae 100-250 part Radix Rhodiolae, 30-70 part Hirudo, 200-400 part Radix Codonopsis, 30-70 part Ganderma lucidum, 30-70 part Radix Ginseng or Radix Panacis Quinquefolii, 80-150 part Herb Gynostemmae Pentaphylli.
Embodiments provide a kind of preparation method of depressor: comprising:
Take raw material;
Raw material described in each is made powder;
All described raw materials are mixed to get the first mixture;
Described first mixture is made pill;
Described pill is dried;
Packaging.
Depressor that the above embodiment of the present invention provides and preparation method thereof, can produce following beneficial effect:
Radix Puerariae, containing Flavonoid substances, puerarin, xylopuerarin, daidzein glycosides, daidzein, containing a small amount of volatile oil, starch, has anti-fatty liver, anti-liver injury, blood fat reducing, antitumor, radioprotective, strengthen immunologic function, there is the effect improving brain blood circulation, have symptoms such as the headache caused because of hypertension, dizzy, tinnitus and pain in the low back and legs and alleviate effect preferably.Often drink Radix Puerariae to treatment hypertension, hyperlipidemia, coronary heart disease, cerebral thrombosis, cervical spondylosis has obvious curative effect.Radix Salviae Miltiorrhizae, has reinforcement myocardial contraction, improves cardiac function, and energy coronary artery dilator arteria coronaria, increases myocardial flow; Expansion peripheral blood vessel, blood flow increases; Cerebral blood flow decline, improve myocardial ischemia situation, reduce blood pressure, calm the nerves with all worries set aside.Rhizoma Chuanxiong is containing ligustrazine and tetramethylpyazine, and ligustrazine energy coronary artery dilator, increases coronary artery blood flow, improves the blood oxygen supply of cardiac muscle, and reduces the oxygen consumption of cardiac muscle; The expansible cerebrovascular of ligustrazine, reduces vascular resistance, significantly increases brain and LBF amount, improves microcirculation; Can surface activity of blood platelet be reduced, suppress platelet aggregation, the formation of pre-preventing thrombosis.The Radix Astragali: have sedation, can strengthen normal heart and shrink, have cardiotonic to the heart of exhaustion.Make tubular blood vessel and renal blood vessels expansion, and make whole body peripheral vasodilation, skin circulation is freely contained, and makes hyperpietic's blood pressure drops.Semen Cassiae, containing anthraquinone analog compound, main is emodin, physcione, chrysophanol, aloe-emodin and obtusifolin, obtusin, yellow obtusin, aurantio-obtusin and their glycoside and chrysophanic acid etc., has good antihypertensive effect.Fructus Crataegi, can increase coronary flow, improves the sensitivity of cardiac muscle to cardiotonic glycoside effect, and can arrhythmia and myocardial ischemia, therefore has blood pressure lowering effect for reducing blood fat.Spica Prunellae, property toil and trembling with fear, enters liver, gallbladder meridian, can liver heat removing and eyesight improving, dispersing swelling and dissipating binds.Spica Prunellae has obvious hypotensive effect, and its extract has antihypertensive activity and antiarrhythmic effect.Radix Rhodiolae, antioxidation, altitude sickness prevention, QI invigorating of making light of one's life by commiting suicide, does not prolong life always, and nontoxic many clothes, clothes of a specified duration are not hurted sb.'s feelings.Can the kidney invigorating, regulate the flow of vital energy and nourish blood, cure mainly the whole body weak, uncomfortable in chest etc.; Also there is promoting blood circulation and hemostasis, clearing away lung-heat to relieve cough, antipyretic, and the effect under leukorrhagia stopping.Hirudo, mainly containing protein, containing blood coagulation substance in saliva, hirudin also has heparin, antithromboxin, there is stronger blood coagulation resisting function, improve microcirculation, suppress platelet aggregation, reduce the stickiness of blood, increase myocardial flow, thrombus, blood fat reducing, the effects such as inhibition tumor cell.Radix Codonopsis, containing sterol, Radix Codonopsis polysaccharide, alkaloid, aminoacid, trace element etc., have and regulate refreshing essence function, excited respiratory center, builds up resistance, resisting fatigue, raw erythrocyte, hemoglobin, the effect that raise blood sugar regulates.Ganderma lucidum, containing polysaccharide, sterols, alkaloid, several amino acids and protein-based etc., has immunomodulating and reduces blood glucose, blood fat reducing, defying age, antitumor, liver function protecting, calm, convulsion, blood pressure lowering, and antitussive such as to breathe heavily at the effect.Radix Ginseng or Radix Panacis Quinquefolii, containing life saponin, volatile oil, amino-acid trace element, containing organic acid, saccharide, vitamin etc., have heart tonifying, promote the synthesis of protein and ribonucleic acid, promote the function of hemopoietic system, cholesterol regulating metabolism, strengthens immunologic function, shock, regulate the excited process with suppressing of cerebral cortex, strengthen neural activity process and motility, increase work efficiency, resisting fatigue, antitumor, anti-inflammatory, antiallergic, blood sugar lowering, antidiuretic, promote the effect (minor can not with) of men and women's gonad function.Herb Gynostemmae Pentaphylli, containing saponin, sterols composition, flavonoid composition.There is enhancing immunologic function, defying age, antitumor, blood fat reducing, anti-stress, anticoagulation, calmness, blood sugar lowering and androgen, estrogen-like effects (minor is unavailable, can not be excessive).Wherein, Radix Panacis Quinquefolii, resisting fatigue, diuresis, anti-hypoxia, blood sugar lowering, calmness, arrhythmia etc., effect supplementing QI and nourishing YIN, relieves inflammation or internal heat and promotes the production of body fluid.
The depressor prepared by these raw materials, can either reach good antihypertensive effect, and side effect is little, can play calm, prevents angiosclerotic effect.
Detailed description of the invention
Below by specific embodiment, the present invention is described in further detail.
Embodiments provide a kind of depressor: its raw material comprises: in mass fraction, 200-400 part Radix Puerariae, 200-400 part Radix Salviae Miltiorrhizae, 80-150 part Rhizoma Chuanxiong, 200-400 part Radix Astragali, 100-250 part Semen Cassiae, 200-400 part Fructus Crataegi, 100-250 part Spica Prunellae 100-250 part Radix Rhodiolae, 30-70 part Hirudo, 200-400 part Radix Codonopsis, 30-70 part Ganderma lucidum, 30-70 part Radix Ginseng or Radix Panacis Quinquefolii, 80-150 part Herb Gynostemmae Pentaphylli.
Embodiments provide a kind of preparation method of depressor: comprising:
Take raw material;
Raw material described in each is made powder;
All described raw materials are mixed to get the first mixture;
Described first mixture is made pill;
Described pill is dried;
Packaging.
Radix Puerariae, containing Flavonoid substances, puerarin, xylopuerarin, daidzein glycosides, daidzein, containing a small amount of volatile oil, starch, has anti-fatty liver, anti-liver injury, blood fat reducing, antitumor, radioprotective, strengthen immunologic function, there is the effect improving brain blood circulation, have symptoms such as the headache caused because of hypertension, dizzy, tinnitus and pain in the low back and legs and alleviate effect preferably.Often drink Radix Puerariae to treatment hypertension, hyperlipidemia, coronary heart disease, cerebral thrombosis, cervical spondylosis has obvious curative effect.Radix Salviae Miltiorrhizae, has reinforcement myocardial contraction, improves cardiac function, and energy coronary artery dilator arteria coronaria, increases myocardial flow; Expansion peripheral blood vessel, blood flow increases; Cerebral blood flow decline, improve myocardial ischemia situation, reduce blood pressure, calm the nerves with all worries set aside.Rhizoma Chuanxiong is containing ligustrazine and tetramethylpyazine, and ligustrazine energy coronary artery dilator, increases coronary artery blood flow, improves the blood oxygen supply of cardiac muscle, and reduces the oxygen consumption of cardiac muscle; The expansible cerebrovascular of ligustrazine, reduces vascular resistance, significantly increases brain and LBF amount, improves microcirculation; Can surface activity of blood platelet be reduced, suppress platelet aggregation, the formation of pre-preventing thrombosis.The Radix Astragali: have sedation, can strengthen normal heart and shrink, have cardiotonic to the heart of exhaustion.Make tubular blood vessel and renal blood vessels expansion, and make whole body peripheral vasodilation, skin circulation is freely contained, and makes hyperpietic's blood pressure drops.Semen Cassiae, containing anthraquinone analog compound, main is emodin, physcione, chrysophanol, aloe-emodin and obtusifolin, obtusin, yellow obtusin, aurantio-obtusin and their glycoside and chrysophanic acid etc., has good antihypertensive effect.Fructus Crataegi, can increase coronary flow, improves the sensitivity of cardiac muscle to cardiotonic glycoside effect, and can arrhythmia and myocardial ischemia, therefore has blood pressure lowering effect for reducing blood fat.Spica Prunellae, property toil and trembling with fear, enters liver, gallbladder meridian, can liver heat removing and eyesight improving, dispersing swelling and dissipating binds.Spica Prunellae has obvious hypotensive effect, and its extract has antihypertensive activity and antiarrhythmic effect.Radix Rhodiolae, antioxidation, altitude sickness prevention, QI invigorating of making light of one's life by commiting suicide, does not prolong life always, and nontoxic many clothes, clothes of a specified duration are not hurted sb.'s feelings.Can the kidney invigorating, regulate the flow of vital energy and nourish blood, cure mainly the whole body weak, uncomfortable in chest etc.; Also there is promoting blood circulation and hemostasis, clearing away lung-heat to relieve cough, antipyretic, and the effect under leukorrhagia stopping.Hirudo, mainly containing protein, containing blood coagulation substance in saliva, hirudin also has heparin, antithromboxin, there is stronger blood coagulation resisting function, improve microcirculation, suppress platelet aggregation, reduce the stickiness of blood, increase myocardial flow, thrombus, blood fat reducing, the effects such as inhibition tumor cell.Radix Codonopsis, containing sterol, Radix Codonopsis polysaccharide, alkaloid, aminoacid, trace element etc., have and regulate refreshing essence function, excited respiratory center, builds up resistance, resisting fatigue, raw erythrocyte, hemoglobin, the effect that raise blood sugar regulates.Ganderma lucidum, containing polysaccharide, sterols, alkaloid, several amino acids and protein-based etc., has immunomodulating and reduces blood glucose, blood fat reducing, defying age, antitumor, liver function protecting, calm, convulsion, blood pressure lowering, and antitussive such as to breathe heavily at the effect.Radix Ginseng or Radix Panacis Quinquefolii, containing life saponin, volatile oil, amino-acid trace element, containing organic acid, saccharide, vitamin etc., have heart tonifying, promote the synthesis of protein and ribonucleic acid, promote the function of hemopoietic system, cholesterol regulating metabolism, strengthen immunologic function, shock, regulating the excited process with suppressing of cerebral cortex, strengthening neural activity process and motility, increasing work efficiency, resisting fatigue, antitumor, anti-inflammatory, antiallergic, blood sugar lowering, antidiuretic, promote the effect of men and women's gonad function, minor can not use.Herb Gynostemmae Pentaphylli, containing saponin, sterols composition, flavonoid composition.Have enhancing immunologic function, defying age, antitumor, blood fat reducing, anti-stress, anticoagulation, calmness, blood sugar lowering and androgen, estrogen-like effects, minor is unavailable, can not be excessive.Wherein, Radix Panacis Quinquefolii, resisting fatigue, diuresis, anti-hypoxia, blood sugar lowering, calmness, arrhythmia etc., effect supplementing QI and nourishing YIN, relieves inflammation or internal heat and promotes the production of body fluid.The depressor prepared by these raw materials, can either reach good antihypertensive effect, and side effect is little, can play calm, prevents angiosclerotic effect.
Next this depressor is described in detail by several specific embodiment:
Embodiment 1: a kind of depressor is provided: its raw material comprises: 200 grams of Radix Puerariaes, 200 grams of Radix Salviae Miltiorrhizaes, 80 grams of Rhizoma Chuanxiongs, 200 grams of Radixs Astragali, 100 grams of Semen Cassiaes, 200 grams of Fructus Crataegis, 100 grams of Spica Prunellaes, 100 grams of Radix Rhodiolaes, 30 grams of Hirudos, 200 grams of Radix Codonopsis, 30 grams of Ganderma lucidum, 30 grams of Radix Ginsengs or Radix Panacis Quinquefoliis, 80 grams of Herb Gynostemmae Pentaphylli.
Embodiment 2: provide a kind of depressor, its raw material comprises: 400 grams of Radix Puerariaes, 400 grams of Radix Salviae Miltiorrhizaes, 150 grams of Rhizoma Chuanxiongs, 400 grams of Radixs Astragali, 250 grams of Semen Cassiaes, 400 grams of Fructus Crataegis, 250 grams of Spica Prunellaes, 250 grams of Radix Rhodiolaes, 70 grams of Hirudos, 400 grams of Radix Codonopsis, 70 grams of Ganderma lucidum, 70 grams of Radix Ginsengs or Radix Panacis Quinquefoliis, 150 grams of Herb Gynostemmae Pentaphylli.
Embodiment 3: provide a kind of depressor, its raw material comprises: 300 grams of Radix Puerariaes, 300 grams of Radix Salviae Miltiorrhizaes, 100 grams of Rhizoma Chuanxiongs, 300 grams of Radixs Astragali, 200 grams of Semen Cassiaes, 300 grams of Fructus Crataegis, 200 grams of Spica Prunellaes, 200 grams of Radix Rhodiolaes, 50 grams of Hirudos, 300 grams of Radix Codonopsis, 50 grams of Ganderma lucidum, 50 grams of Radix Ginsengs or Radix Panacis Quinquefoliis, 100 grams of Herb Gynostemmae Pentaphylli.
In certain embodiments, in selection, Spica Prunellae preferably selects wounded in the battle Spica Prunellae, and ripe is better, is rich in more nutritive value; Semen Cassiae is preferably the Semen Cassiae fried, after frying can blood fat reducing, blood pressure, if do not fried, eaten easy diarrhoea; Fructus Crataegi is preferably made a living, and raw Fructus Crataegi sarcocarp possesses hypotensive activity; Hirudo is preferably the Hirudo of the process of preparing Chinese medicine, and the Hirudo of the process of preparing Chinese medicine has treatment apoplexy, resisting hypertension, desilting, antithrombotic, and Hirudo carries more antibacterial, parasite, by concocting the effect that can reach sterilizing, thus avoids antibacterial to be incorporated in medicine.
It should be noted that:
1. Radix Ginseng or Radix Panacis Quinquefolii adult's application all relatively, minor needs to remove in prescription.
If 2. the deficiency of YIN, hyperactivity of fire, excessive rising of liver-YANG person need to use the formula containing Radix Panacis Quinquefolii.
3. this prescription is particularly useful for mild or moderate hyperpietic.
The depressor prepared by above-mentioned raw materials can make watered pill, is convenient for people to take.
Depressor in corresponding the various embodiments described above, then describe this preparation method in detail by some embodiments:
Step 101, chooses raw Fructus Crataegi;
Step 102, chooses wounded in the battle Spica Prunellae;
It should be noted that, step 101,102 liang of steps can not adopt in certain embodiments.
Step 103, takes each raw material of depressor;
The amount of taking, can continue to use the raw material addition of the depressor of the various embodiments described above in various embodiments.
Step 104, fries Semen Cassiae;
Step 105, concocts Hirudo;
It should be noted that, step 104,105 can not adopt in certain embodiments.
Step 106, will choose and process raw material and make powder through above-mentioned;
Step 107, is mixed to get the first mixture by the powder of all raw materials;
Step 108, makes pill by the first mixture, and the size of pill is like Semen phaseoli radiati;
Step 109, dries pill;
Step 110, packaging.
Through depressor prepared by said method, the oral 10g of each warm water, Time of Administration is 2 hours after meal, according to the state of an illness tight weight every day 2-3 time, every three months is a course for the treatment of, but takes medicine period and take blood pressure when dropping to normal, every day oral 10g or the next day once oral, consolidate curative effect
The depressor of above-mentioned preparation is carried out clinical experiment:
Case 1: Xiong (female) 63 years old
The state of an illness: essential hypertension is with throat pharynx, hyperhidrosis, the fearness sun, no fur on tongue, jag is scarlet, can not carry out slight physical work, within about 40 years old, disease is sent out, the effect that always has Western medicine is bad, " the nifedipine controlled release tablet " of eating each 10 milligrams, three times on the one, an a slice, fluctuation of blood pressure on July 22 in 2011 at 200-160/100-110mmhg, blood pressure does not fall always, and every night, insomnia was greater than more than one week.(note: be always sick for thing at night, insomnia, dysphoria, just dizzy, headache in second day) treatment: every day oral medicine pill 2 times, sooner or later each 10g, temporary transient Western medicine does not stop (three on the one), starts sleep and take a turn for the better after 7 days, but blood pressure does not fall, Western medicine oral dose every day does not reduce temporarily, and then continue pills one week again, blood pressure declines to some extent, blood pressure drops number is 150/95mmhg(millimetres of mercury), Western medicine oral dose is reduced to every day 2.After the bimester of clothes more again, blood pressure reduces to 130/90mmhg, then 120/85mmhg after oral three months, and sleep is normal, then oral medicine pill is normal to blood pressure when about 12 months, and oral a slice next day of Western medicine, every day, oral medicine pill 10g was consolidated.By 2013, patient was substantially normal so far, within blood pressure remains on normal range value.And be not afraid of now the sun, not dizzy, do things and be not afraid of toil, all are normal for mental attitude, also can do mild or moderate physical work.
Case 2: father-in-law (man) 81 years old
The state of an illness: hypertension for many years, dizzy, headache
Treatment: the Western medicine blood pressure lowering that the normal phase eats, old people thinks that side effect is very large, adds the ball that takes traditional Chinese medicine, each 10g, every day 2 times, and during continuous oral 3 months, blood pressure is down to normally, stops Western medicine, and eat 10g consolidation every day, all are normal for mental attitude.Patient has sent a silk banner and the letter of thanks on July 7th, 2013.
Case 3: Tan (man) 59 years old
On January 3rd, 2012 is first, hypertension 160/110mmhg, every day eats " reserpine " each a slice, one day three times, eat rear blood pressure and can drop to 140/100mmhg, then skull pain, does things tired, fat, the enlargement of right lower extremity toe middle finger end, having becomes silted up swells, and toe point becomes large, toenail necrosis.This side eats 1 dose, stops having Western medicine, every day twice Chinese medicine pill, after each 10 grams, 2013-3-28 bis-diagnosis eat the 2nd dose, and readme is caught a cold afterwards or after removing weight, blood pressure only has 150/90mmhg, when having no interest or do not remove weight, blood pressure is 130/85mmhg, and become silted up swollen symptom of toe disappears a lot.After eating the 3rd dose, lower limb toe becomes silted up to swell and all eliminates, and has grown new toenail, and patient is very glad.
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for a person skilled in the art, the present invention can have various modifications and variations.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. a depressor, it is characterized in that, its raw material is composed of the following components: in mass fraction, 200-400 part Radix Puerariae, 200-400 part Radix Salviae Miltiorrhizae, 80-150 part Rhizoma Chuanxiong, 200-400 part Radix Astragali, 100-250 part Semen Cassiae, 200-400 part Fructus Crataegi, 100-250 part Spica Prunellae 100-250 part Radix Rhodiolae, 30-70 part Hirudo, 200-400 part Radix Codonopsis, 30-70 part Ganderma lucidum, 30-70 part Radix Ginseng or Radix Panacis Quinquefolii, 80-150 part Herb Gynostemmae Pentaphylli.
2. depressor according to claim 1, it is characterized in that, its raw material is composed of the following components: in mass fraction, 300 parts of Radix Puerariaes, 300 parts of Radix Salviae Miltiorrhizaes, 100 parts of Rhizoma Chuanxiongs, 300 parts of Radixs Astragali, 200 parts of Semen Cassiaes, 300 parts of Fructus Crataegis, 200 parts of Spica Prunellaes, 200 parts of Radix Rhodiolaes, 50 parts process Hirudo, 300 portions of Radix Codonopsis, 50 parts of Ganderma lucidum, 50 parts of Radix Ginsengs or Radix Panacis Quinquefoliis, 100 portions of Herb Gynostemmae Pentaphylli.
3. depressor according to claim 1 and 2, is characterized in that, described Spica Prunellae is wounded in the battle Spica Prunellae.
4. depressor according to claim 1 and 2, is characterized in that, described Semen Cassiae is the Semen Cassiae fried.
5. depressor according to claim 1 and 2, is characterized in that, described Fructus Crataegi is made a living.
6. depressor according to claim 1 and 2, is characterized in that, described Hirudo be concoct process Hirudo.
7. depressor according to claim 1 and 2, is characterized in that, the dosage form of described depressor is watered pill.
8. the preparation method of the depressor described in any one of claim 1-7, is characterized in that, comprising:
Take raw material;
Raw material described in each is made powder;
The powder of all described raw materials is mixed to get the first mixture;
Described first mixture is made pill;
Described pill is dried;
Packaging.
9. preparation method according to claim 8, is characterized in that,
Described take raw material after, described raw material described in each made powder before, described preparation method also comprises:
Described Semen Cassiae is carried out parch;
Described Hirudo is concocted.
10. preparation method according to claim 9, is characterized in that,
Described take raw material before, described preparation method also comprises:
Choose raw described Fructus Crataegi;
Choose wounded in the battle described Spica Prunellae.
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CN104906495A (en) * | 2015-06-11 | 2015-09-16 | 乐瑛 | Hypertension symptom improvement medicine mainly using rhodiola rosea |
CN105169197A (en) * | 2015-09-03 | 2015-12-23 | 哈尔滨泉兴科技有限公司 | Traditional Chinese medicine for efficiently and fast lowering blood pressure |
CN105853506A (en) * | 2016-05-09 | 2016-08-17 | 张钊 | Hypotensive healthcare medicine composition containing five-leaf gynostemma herb |
CN107261015A (en) * | 2017-06-21 | 2017-10-20 | 佛山科学技术学院 | A kind of anti-hypertensive electuary and preparation method thereof |
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CN101129817A (en) * | 2007-09-26 | 2008-02-27 | 王福春 | Chinese medicine formulation for treating hypertension and method of producing the same |
CN101595927A (en) * | 2008-06-06 | 2009-12-09 | 刘泳宏 | A kind of natural lung-nourishing lipopenicillinase, hypoglycemic, blood-pressure decreasing tea and preparation method |
CN101612223A (en) * | 2008-06-26 | 2009-12-30 | 崔艳 | Traditional Chinese medicine for benefiting heart and strengthening brain |
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CN101129817A (en) * | 2007-09-26 | 2008-02-27 | 王福春 | Chinese medicine formulation for treating hypertension and method of producing the same |
CN101595927A (en) * | 2008-06-06 | 2009-12-09 | 刘泳宏 | A kind of natural lung-nourishing lipopenicillinase, hypoglycemic, blood-pressure decreasing tea and preparation method |
CN101612223A (en) * | 2008-06-26 | 2009-12-30 | 崔艳 | Traditional Chinese medicine for benefiting heart and strengthening brain |
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Granted publication date: 20150128 Termination date: 20171016 |