CN102210848B - Medicament for treating skin disease, and preparation method thereof - Google Patents
Medicament for treating skin disease, and preparation method thereof Download PDFInfo
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- CN102210848B CN102210848B CN2011101481039A CN201110148103A CN102210848B CN 102210848 B CN102210848 B CN 102210848B CN 2011101481039 A CN2011101481039 A CN 2011101481039A CN 201110148103 A CN201110148103 A CN 201110148103A CN 102210848 B CN102210848 B CN 102210848B
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- 239000003814 drug Substances 0.000 title claims abstract description 37
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 208000017520 skin disease Diseases 0.000 title abstract description 4
- 235000014443 Pyrus communis Nutrition 0.000 claims abstract description 14
- 241000220324 Pyrus Species 0.000 claims description 14
- 239000000203 mixture Substances 0.000 claims description 12
- 241000628997 Flos Species 0.000 claims description 8
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims description 4
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 claims description 4
- 241001161070 Calomela Species 0.000 claims description 4
- 241000190633 Cordyceps Species 0.000 claims description 4
- 241000283956 Manis Species 0.000 claims description 4
- 241000972155 Moschus Species 0.000 claims description 4
- 241000124079 Mylabris Species 0.000 claims description 4
- 229940025250 camphora Drugs 0.000 claims description 4
- 239000010238 camphora Substances 0.000 claims description 4
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 4
- 239000002994 raw material Substances 0.000 claims description 4
- 229910052957 realgar Inorganic materials 0.000 claims description 4
- 238000000605 extraction Methods 0.000 claims description 2
- 238000012856 packing Methods 0.000 claims description 2
- 235000021017 pears Nutrition 0.000 claims description 2
- 230000002787 reinforcement Effects 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 6
- 238000000034 method Methods 0.000 abstract description 5
- 230000001737 promoting effect Effects 0.000 abstract description 5
- 230000017531 blood circulation Effects 0.000 abstract description 4
- 239000008280 blood Substances 0.000 abstract description 3
- 210000004369 blood Anatomy 0.000 abstract description 3
- 239000003053 toxin Substances 0.000 abstract description 3
- 231100000765 toxin Toxicity 0.000 abstract description 3
- 206010062717 Increased upper airway secretion Diseases 0.000 abstract description 2
- 230000019522 cellular metabolic process Effects 0.000 abstract description 2
- 208000026435 phlegm Diseases 0.000 abstract description 2
- 239000006188 syrup Substances 0.000 abstract 2
- 235000020357 syrup Nutrition 0.000 abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 230000003467 diminishing effect Effects 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000007721 medicinal effect Effects 0.000 abstract 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 11
- 229940079593 drug Drugs 0.000 description 7
- 230000008859 change Effects 0.000 description 4
- 201000004681 Psoriasis Diseases 0.000 description 3
- 241000219780 Pueraria Species 0.000 description 3
- 230000004888 barrier function Effects 0.000 description 3
- 210000002615 epidermis Anatomy 0.000 description 3
- 210000002683 foot Anatomy 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 206010048768 Dermatosis Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 241000842539 Rhagades Species 0.000 description 1
- 206010040849 Skin fissures Diseases 0.000 description 1
- 208000002474 Tinea Diseases 0.000 description 1
- 241000130764 Tinea Species 0.000 description 1
- 206010067197 Tinea manuum Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000007765 cera alba Substances 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 238000010411 cooking Methods 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 210000003780 hair follicle Anatomy 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 210000001699 lower leg Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 210000001732 sebaceous gland Anatomy 0.000 description 1
- 230000008591 skin barrier function Effects 0.000 description 1
- 208000028882 split hand Diseases 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 210000000106 sweat gland Anatomy 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 201000004647 tinea pedis Diseases 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a medicament for treating skin disease, and a preparation method thereof. The medicament for treating skin disease is mainly characterized in that a proper amount of various traditional Chinese medicines are added to a prepared pear syrup for mixed use. The medicament disclosed by the invention has low cost and a simple method in preparation, and the pear syrup has multiple efficacies on promoting blood circulation by removing blood stasis, stopping asthma, resolving phlegm, promoting blood circulation and dredging collateral, moistening skin and beautifying, diminishing inflammation and promoting skin and cell metabolism, expelling toxin, drawing out toxin and detoxifying. Simultaneously, various effective traditional Chinese medicinal materials are added, so that the medicinal effect is more obvious, and no negative effect is caused.
Description
Technical field
The present invention relates to a kind of dermopathic medicine and preparation method thereof for the treatment of, belong to the field of Chinese medicines.
Background technology
Skin is the outermost layer tissue of human body; its barrier action is that various organs and tissue are avoided in the external environment machinery, physics, chemistry and biological harmful factor damage in the protection body, can prevent again organization internal various nutrient substance, electrolyte, thank with the mistake of moisture.Skin is to be formed by epidermis, corium and subcutaneous tissue, horny layer in its epidermis is to absorb main barrier position through skin, studies show that, the chemicals transdermal flux is a kind of passive process of expansion, permeability depends on the whether integrity of the barrier structure of skin, and when skin is subjected to the external world or the infiltration of physical chemistry thing, it will change in various degree, the skin barrier structure is changed, help medicine to pass through transdermal and absorb.
Medicine absorbs through skin, enters corium by horny layer and active epidermis and is absorbed by blood capillary and enter the human recycle system, also can heat outward or attached apparatus and by hair follicle, sebaceous gland and sweat gland absorption.The speed that absorbs is fast.
Summary of the invention
The object of the invention is to provide a kind of dermopathic medicine and preparation method thereof for the treatment of.
The present invention adopts following technical scheme to achieve these goals:
Treat dermopathic medicine, it is characterized in that comprising pear paste and Chinese medicine composition.
The dermopathic medicine of described treatment, the weight portion that it is characterized in that described Chinese medicine composition is Caulis et Folium Brassicae junceae 38-42g; Cordyceps 8-12g; Cortex Kalopanacis 95-105g; Realgar 28-32g; Radix Stemonae 95-105g; Radix Et Rhizoma Rhei 12-16g; Cornu Cervi Pantotrichum 45-55g; Calculus Bovis 8-12g; Herba euphorbiae lunulatae 14-16g; artificial Moschus 3-5g; Mylabris 28-32g; Rhizoma Arisaematis 28-32g; Herba Taraxaci 45-55g; Flos Chrysanthemi Indici 8-12g; Fructus Cnidii 14-16g; Rhizoma Pinelliae 14-16g; Camphora 8-12g; Herba Typhonii gigantei 38-42g; Radix Sophorae Flavescentis 28-32g; Radix Aconiti 8-12g; Radix Aconiti Kusnezoffii 8-12g; Herba speranskiae tuberculatae 95-105g; Lignum Aquilariae Resinatum 28-32g; Radix Rehmanniae 8-12g; Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 2.5-3.5g; Fructus Crotonis 6-10g; Flos Carthami 28-32g; Radix Saposhnikoviae 28-32g; Radix Angelicae Dahuricae 22-26g; Rhizoma Zingiberis 14-16g; Folium Bambusae 70-80g; Squama Manis 18-22g; Radix Glycyrrhizae 28-32g; Calomelas 8-12g; Fructus Piperis 24-26g; Borneolum Syntheticum 10-14g; Radix Angelicae Sinensis 28-32g; Herba Asari 10-14g.
The dermopathic medicine of described treatment, the weight portion that it is characterized in that described Chinese medicine composition is Caulis et Folium Brassicae junceae 40g; Cordyceps 10g; Cortex Kalopanacis 100g; Realgar 30g; Radix Stemonae 100g; Radix Et Rhizoma Rhei 15g; Cornu Cervi Pantotrichum 50g; Calculus Bovis 10g; Herba euphorbiae lunulatae 15g; artificial Moschus 4g; Mylabris 30g; Rhizoma Arisaematis 30g; Herba Taraxaci 50g; Flos Chrysanthemi Indici 10g; Fructus Cnidii 15g; Rhizoma Pinelliae 15g; Camphora 10g; Herba Typhonii gigantei 40g; Radix Sophorae Flavescentis 30g; Radix Aconiti 10g; Radix Aconiti Kusnezoffii 10g; Herba speranskiae tuberculatae 100g; Lignum Aquilariae Resinatum 30g; Radix Rehmanniae 10g; Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 3g; Fructus Crotonis 8g; Flos Carthami 30g; Radix Saposhnikoviae 30g; Radix Angelicae Dahuricae 25g; Rhizoma Zingiberis 15g; Folium Bambusae 75g; Squama Manis 20g; Radix Glycyrrhizae 30g; Calomelas 10g; Fructus Piperis 25g; Borneolum Syntheticum 12g; Radix Angelicae Sinensis 30g; Herba Asari 12g.
The preparation method of the dermopathic medicine of described treatment is characterized in that may further comprise the steps:
(1) extraction of pear paste preparation:
Pear is shredded with cutter, with broken pears on the sack dress, press juice, Sucus Pyri flows into to be put in the container of juice, then clean pure Sucus Pyri is put into pot earlier with the temperature baked wheaten cake till open, fiery about 45 minutes of reinforcement, the little baked wheaten cake of reuse is brown, burn till the black paste with slow fire, cooled off about 30 minutes, packing;
(2) preparation of Chinese medicine composition:
Above-mentioned raw material of Chinese medicine is made Powdered, single bottling is taken according to dosage.
The preparation method of the dermopathic medicine of described treatment is characterized in that described pear paste, Chinese medicine composition mix use, get above-mentioned each Chinese medicinal powder according to patient's the state of an illness and put into dispenser, add rare pear paste, coating, reactionless after 10-15 minute, enlarge the medication area, repeat 3-4 time.
Beneficial effect of the present invention:
The cost of medication preparation of the present invention is low, method is simple, and wherein pear paste can blood circulation promoting and blood stasis dispelling, Zhichuan, reduce phlegm, promoting blood circulation to remove obstruction in the collateral, promotes that skin moistens magnificent appearance, and antiinflammatory promotes skin and cellular metabolism, toxin expelling, proposes poison, detoxifcation, multinomial effect; Add multiple effective Chinese crude drug simultaneously, made effect more obvious, do not had any negative effect.
The specific embodiment
Pear paste of the present invention, Chinese medicine composition mix and use, and gets the Chinese medicinal powder of having made according to patient's the state of an illness and put into dispenser, adds rare pear paste, and coating is in affected part, and is reactionless after 10-15 minute, and expansion medication area repeats 3-4 time.
Embodiment one: Li Xinjian, and the man, 48 years old, the finance of Dangshan County Pueraria lobota collection was worked.On January 13rd, 2007 went to a doctor, and there are 10 centimeters long 15 centimeters nerve psoriasiss the root top behind the right crus of diaphragm, had controlled 79 days 1 cycles through the top and had cured 75%; Taking is to change medicine about 48 hours one time, when changing dressings solar day according to 20-30 minute, oxygen uptake, and then change dressings, repeated multiple times like this.Second course for the treatment of than last time dose add 1/3rd usefulness several times after, the thin check also has three points at second basic unit's Intradermal, and the needle point size is arranged, and continues medication, four surplus points also continue medication again, recovery from illness in 14 days, recurrence so far.
Embodiment two: Wang Ermin, woman, 23 years old, 10 groups of Da Wang people from village in Fan Tao village, Dangshan County Pueraria lobota market town.On March 3rd, 2000 went to a doctor, on one's body, on the lower limb, before and after the back polylith dermatosis is arranged, through careful examination, be confirmed to be speckle gonosome tinea or claim the speckle psoriasis, block size differs, and big has tens centimeters, little 1-3 centimetre, in many ways seek medical advice and do not heal, bad during fashion, recurrence always.With cycle course for the treatment of of top treatment, treatment 50-55% proposes toxicity and obviously protrudes bulk through me, and in various degree the same with good skin arranged after the incrustation, second the course for the treatment of effect obvious especially, all be strict sterilization three times at every turn, apply medicinal lotion or ointment three times, fix again.Pull down before changing dressings next time, shined upon 20-30 minute, makes skin absorbs oxygen, repeated multiple times like this, and 2 cycles recoveries from illness, recurrence so far, existing more than ten years.
Embodiment three: Xu Ruojun, and 59 years old, psoriasis there are 50 years on the foot, white beeswax garden village, Dangshan County Pueraria lobota market town summer Zhu Zhuan people, readme is sought medical advice in many ways, fails to cure my tinea pedis for many years.On January 3rd, 2000 went to a doctor, and can not walk, and breach has 0.8 openning repeatedly, swelling of the feet rises, I am very painful, am reporting the idea of trying, and am good with immobilization with adhesive tape again with medicine-feeding through sterilization, after 1 hour, foot can land and slowly can walk, and he says very refreshing, fully recovers with two weeks by repeated multiple times, do manual work for many years in the other places now, so far not recurrence.
Embodiment four: Hou Yuzhi, each Fan Tao people from village, market town of Dangshan County, Da Wang people from village.On August 1st, 1998 went to a doctor, and the split hand mouth does not have several, and mouthful big have half centimeter degree of depth, swell and rise by rhagades of the skin as stinging, cooking work all can't be carried out, and loses by the thing ability, readme is sought medical advice in many ways, sees heavier and heavier, washes the method rubbing method, with a lot of, all there is not effect, use on the contrary and more split, medical history is after began existing 6 years, by a little bit smaller, to present situation, carefully check through me, think a kind of tinea manuum, the intractable type, it is basic at first will to solve, and sterilize after three times, and first light is wiped with pear paste and tried staitinodermia after 1 hour, finger can have been held thing, I am very pleased, concoct our medicamental pulverata again for the second time, come again once in 15 minutes, so just with being ready to the fixing wrapping of husky cloth, changed medicine in 48 hours one time, change the husky cloth of dismantling, shined upon 20-30 minute, repeated multiple times was fully recovered through January like this, so far not recurrence.
Claims (2)
1. the psoriasic external used medicine for the treatment of is characterized in that being made up of pear paste and Chinese medicine composition; The parts by weight of raw materials of described Chinese medicine composition is Caulis et Folium Brassicae junceae 38-42g, Cordyceps 8-12g, Cortex Kalopanacis 95-105g, Realgar 28-32g, Radix Stemonae 95-105g, Radix Et Rhizoma Rhei 12-16g, Cornu Cervi Pantotrichum 45-55g, Calculus Bovis 8-12g, Herba euphorbiae lunulatae 14-16g, artificial Moschus 3-5g, Mylabris 28-32g, Rhizoma Arisaematis 28-32g, Herba Taraxaci 45-55g, Flos Chrysanthemi Indici 8-12g, Fructus Cnidii 14-16g, Rhizoma Pinelliae 14-16g, Camphora 8-12g, Herba Typhonii gigantei 38-42g, Radix Sophorae Flavescentis 28-32g, Radix Aconiti 8-12g, Radix Aconiti Kusnezoffii 8-12g, Herba speranskiae tuberculatae 95-105g, Lignum Aquilariae Resinatum 28-32g, Radix Rehmanniae 8-12g, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 2.5-3.5g, Fructus Crotonis 6-10g, Flos Carthami 28-32g, Radix Saposhnikoviae 28-32g, Radix Angelicae Dahuricae 22-26g, Rhizoma Zingiberis 14-16g, Folium Bambusae 70-80g, Squama Manis 18-22g, Radix Glycyrrhizae 28-32g, Calomelas 8-12g, Fructus Piperis 24-26g, Borneolum Syntheticum 10-14g, Radix Angelicae Sinensis 28-32g, Herba Asari 10-14g; The preparation method for the treatment of dermopathic medicine may further comprise the steps:
(1) extraction of pear paste preparation:
Pear is shredded with cutter, with broken pears on the sack dress, press juice, Sucus Pyri flows into to be put in the container of juice, then clean pure Sucus Pyri is put into pot earlier with the temperature baked wheaten cake till open, fiery about 45 minutes of reinforcement, the little baked wheaten cake of reuse is brown, burn till the black paste with slow fire, cooled off about 30 minutes, packing;
(2) preparation of Chinese medicine composition:
Above-mentioned raw material of Chinese medicine is made Powdered, single bottling is taken according to dosage.
2. psoriasic external used medicine according to claim 1, the parts by weight of raw materials that it is characterized in that described Chinese medicine composition is Caulis et Folium Brassicae junceae 40g; Cordyceps 10g; Cortex Kalopanacis 100g; Realgar 30g; Radix Stemonae 100g; Radix Et Rhizoma Rhei 15g; Cornu Cervi Pantotrichum 50g; Calculus Bovis 10g; Herba euphorbiae lunulatae 15g; artificial Moschus 4g; Mylabris 30g; Rhizoma Arisaematis 30g; Herba Taraxaci 50g; Flos Chrysanthemi Indici 10g; Fructus Cnidii 15g; Rhizoma Pinelliae 15g; Camphora 10g; Herba Typhonii gigantei 40g; Radix Sophorae Flavescentis 30g; Radix Aconiti 10g; Radix Aconiti Kusnezoffii 10g; Herba speranskiae tuberculatae 100g; Lignum Aquilariae Resinatum 30g; Radix Rehmanniae 10g; Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 3g; Fructus Crotonis 8g; Flos Carthami 30g; Radix Saposhnikoviae 30g; Radix Angelicae Dahuricae 25g; Rhizoma Zingiberis 15g; Folium Bambusae 75g; Squama Manis 20g; Radix Glycyrrhizae 30g; Calomelas 10g; Fructus Piperis 25g; Borneolum Syntheticum 12g; Radix Angelicae Sinensis 30g; Herba Asari 12g.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2011101481039A CN102210848B (en) | 2011-06-03 | 2011-06-03 | Medicament for treating skin disease, and preparation method thereof |
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| CN2011101481039A CN102210848B (en) | 2011-06-03 | 2011-06-03 | Medicament for treating skin disease, and preparation method thereof |
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| CN102210848A CN102210848A (en) | 2011-10-12 |
| CN102210848B true CN102210848B (en) | 2013-08-14 |
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Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102793879A (en) * | 2012-04-26 | 2012-11-28 | 王明朗 | Compound ointment for treating beriberi and foot odor |
| CN102895414B (en) * | 2012-09-10 | 2014-03-26 | 顾康春 | Chinese herbal paste for treating superficial cancer |
| CN103142972B (en) * | 2013-03-22 | 2014-02-05 | 郑海雁 | Medicine for treating children dermatosis |
| CN103341106B (en) * | 2013-07-29 | 2016-01-20 | 北京百睿宏嘉生物科技有限公司 | A kind of Cordyceps antimicrobial inflammation-relieving gel and preparation method thereof |
| CN103536719A (en) * | 2013-09-24 | 2014-01-29 | 张孝昌 | Traditional Chinese medicine formula for treating presbyopia |
| CN103784833A (en) * | 2014-02-08 | 2014-05-14 | 张孝昌 | Traditional Chinese medicine for treating dermatophytosis and tinea pedis |
| CN104107367A (en) * | 2014-07-21 | 2014-10-22 | 河南科技大学第一附属医院 | Ointment for treating tinea and preparation method thereof |
| CN104815103A (en) * | 2015-04-02 | 2015-08-05 | 牛太贵 | Toxin removal powder |
| CN105106867A (en) * | 2015-09-29 | 2015-12-02 | 李文远 | Traditional Chinese medicine-western medicine composite external preparation for treating eczematous dermatitis and herpes and application thereof |
| CN109331043A (en) * | 2018-11-19 | 2019-02-15 | 青海民族大学 | A kind of medicinal composition for treating carbuncle furuncle and preparation method thereof |
-
2011
- 2011-06-03 CN CN2011101481039A patent/CN102210848B/en not_active Expired - Fee Related
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| 苗明三.中药不良反应.《河南中医药学刊》.2001,第16卷(第2期), * |
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