CN100381137C - Wound repairing and burns treating cream - Google Patents

Abstract

The present invention relates to a burn ointment for healing wounds, which is prepared from Chinese herbal drugs such as giant knotweed rhizome, Polygonum ciliinerve Nakai Ohwi, borneol, pearl powder, licorice root, sesame oil, etc. by the procedures of material preparation, pulverization, sesame oil immersion, boiling, lixiviation, agitation, packaging and sterilization. The statistics of 1287 patients which are treated by an armed police special burn hospital show that the burn ointment has an effective rate of 99.45% and a cure rate of 95.18%, and no scar or few scares are left after healing; the healing time of burns below a superficial second degree is from 6 to 12 days with 9.02 days on average, and the healing time of a deep second degree burn wound is 16 to 25 days with 20 days on average; the burn ointment can accelerate the decrustation of the eschar of a third degree burn wound, and the burn ointment is favourable for autologous skin grafting as soon as possible; the healing time of a third degree burn in a small area is from 26 to 50 days with 32.44 days on average. The ointment is prepared from the Chinese herbal drugs, and the present invention has the advantages of abundant raw materials, low price and convenient use. The ointment only needs to be directly smeared on a common burn; as for a severe burn or a chemical burn, simple debridement is needed, and then the ointment is smeared on aseptic gauze which is applied to a wound and is changed once a day. The burn ointment is suitable for the treatment of various burns and scalds.

Description

The burn cream of reconstructing

One, affiliated technical field:

The present invention relates to a kind of treatment and burn the Chinese herbal medicine for external use cream that (scalding) hinders.

Two, background technology:

Burn, comprise scald, chemical burn, electrically contact wound, it is a kind of common wound in the daily life, especially the burn in the war will account for the whole wounded's 70～80%, therefore, the medicine of treatment burn should be a kind of medicine commonly used, popular medicine, not only kind is few but be used for the treatment of the medicine of burn at present, and effect is also undesirable.The current medicine commonly used that is used for burn wound's treatment mainly contains two classes: a class is a Western medicine, use at most with the antibiotic silver sulfadiazine, but this medicine is through long-term a large amount of clinical practices, find that it not only can not avoid burn wound to infect fully, and to epithelial growth generation inhibition, can wound surface also can cause zest pain when using, continue with going down, and is existing in many disputes; Modern times and the synthetic antibiotic of silver ion are not found good prospects for application such as medicines such as norfloxacin silver yet.Another kind of is Chinese medicine, and on behalf of medicine, it JINGWANHONG RUANGAO and moist expose burn ointment are arranged, though JINGWANHONG RUANGAO has been used for many years, because of its infection, analgesic effect are imprecise, do not see to be used for large burn clinical report, and medicament sources is subjected to certain restriction; Moist expose burn ointment is the new drug through state approval production for treating burn, also because of its anti-infective effect is imprecise, easily causes the wound surface dipping to deepen and be restricted.

Three, summary of the invention:

Undesirable in order to overcome existing treatment burn medicine pain relieving and anti-infective effect, defective such as the medicine source is not extensive, the invention provides a kind of is the burn cream of reconstructing of primary raw material with the Chinese herbal medicine, to alleviate fire victim's misery, improves the cure rate of burn patient.

For solving its technical problem, the technical solution adopted in the present invention is: according to the theory of Chinese medicine to burn wound's repairing and treating, control with dialectical opinion and to be the basis, implement the principle of " it is short that heat-clearing and toxic substances removing-be antibacterial bacteriostatic, blood circulation promoting and blood stasis dispelling-be pain relieving, skin moistening are supported skin-promptly protect wound ", adopt and dredge space between skin and muscles, the circulation QI and blood, promoting blood circulation and stopping pain, removing summer-heat fire-toxin, putrefaction-removing granulation-promoting, the skin moistening controlling nocturnal emission with astringent drugs is supported the Chinese herbal medicine of the living liquid of skin and is treated burn.The composition of this ointment is: Rhizoma Polygoni Cuspidati (Rhizoma), Polygonum ciliinerve Nakai Ohwi. (Polygonum Cillinerre Ohwi), Borneolum Syntheticum, Margarita powder, Radix Glycyrrhizae, substrate (Oleum Sesami, Cera Flava, a small amount of medical ventolin).The weight proportion of each composition is: Rhizoma Polygoni Cuspidati 250～300 grams, Polygonum ciliinerve Nakai Ohwi. 250～320 grams, Borneolum Syntheticum 10～20 grams, Margarita powder 10～20 grams, Radix Glycyrrhizae 80～120 grams, Cera Flava 100～150 grams, Oleum Sesami 1500～2000ml.

Processing method: get all the each raw material of Chinese medicine ready by proportioning earlier, after again 100 mesh sieves being pulverized in Rhizoma Polygoni Cuspidati, Polygonum ciliinerve Nakai Ohwi., Radix Glycyrrhizae processing, soaked 20～30 hours with Oleum Sesami, boiled 30～60 minutes with double boiler then, cooling is below 80 ℃, remove lixiviate Oleum Sesami liquid 800～1000ml that fiber impurity must contain former medicine with filtered through gauze, adding Cera Flava stirs evenly, when being cooled to 50 ℃, add Borneolum Syntheticum, Margarita powder and an amount of medical ventolin stirring and adjusting and become the suitable ointment of soft or hard, 40～45 gram collapsible tubes of packing into seal, and use cobalt (CO at last ⁶⁰) irradiation sterilization, detect and asepticly be finished product after qualified.

Using method is: earlier with 1: 2000 bromo geramine solvent clean wound surface, chelated iodine to the center sterilization, has the wound surface of blister from edge of wound 2～5cm place, low level to take out and steeps liquid, keep the bubble skin, to fall losing or with serious pollution wound surface beancurd sheet is removed, it is thick then this ointment to be applied on the sterile gauze about 0.2～0.4cm, presses the wound surface size, stick on wound surface, be advisable to surpass edge of wound 1～2cm, simple dressing, once a day.For polluting light fresh wound surface, direct coating, seriously polluted or chemical burn person wants clean wound surface with clean water earlier, direct coating behind the regular debridement, disinfection, blister type wound surface, low level take out steep liquid after unction again.Under the effect of this ointment of degree of depth wound surface, there are a large amount of whites or flaxen liquefaction thing to overflow outside wound surface medicine layer, after available gauze or absorbent cotton roll gently and wipes away, continue coating, be sure not firmly wiping wound tissue.Can heal rapidly behind the shallow II degree wound surface coating, dark II, III degree burn wound should be in time in the up auto-skin grafting arts of granulation wound behind dressing change after a while.

Points for attention: 1, burn wound's pressurized that should avoid friction; 2, the wound surface cleaning and sterilizing agent should be selected your Thailand of chelated iodine, 1: 2000 bromo geramine solution or art etc. for use; 3, but this ointment is in the deliquescing in summer, and the hardening in winter belongs to normal phenomenon, uses after the deliquescing as long as the ointment of hardening heated; 4, suffering from winter all should be warming, and room temperature is advisable with 18～32 ℃; 5, use this ointment therapist, whole body therapeutic is pressed the surgery conventional treatment.

The invention has the beneficial effects as follows: 1. this ointment is to the good effect of burn patient, according to clinical treatment 1287 routine fire victim's statistics, abandon more not leaving hospital 7 examples midway, effective 1280 examples, effective percentage 99.45%, operation transplantation is from body skin 55 examples, all the other are spontaneous recovery, cure rate 95.18%, and the effective percentage of common burn medicine has only about 90%, cure rate 70%.For the healing time below the shallow II degree is 6～12 days, and average 9.02 days, for the deep ii degree burn wound surface, healing time was 16～25 days, average 20 days; For III degree burn wound, can impel eschar to shift to an earlier date decrustation, be beneficial to autologous transplanting skin as early as possible, and small size III degree healing time is 26～50 days, average 32.44 days, all than using Western medicine class burn medicine 2～7 days in advance.The treatment healing was followed up a case by regular visits to 68 examples in back 3 months, and its function situation is: shallow II degree healing wound surface does not all have cicatrix, and dark II degree healing wound surface is smooth, there is not obvious scar hyperplasia, after adopting lasting elastic sleeve compression therapeutic, function is accessible, and its function situation also obviously is better than common burn medicine.2. the raw material of this ointment adopts the Chinese herbal medicine medical material, and the medicine source of China's Chinese medicinal herbs is abundant, and processing is simple, so cost is low, low price; 3. easy to use, general burn wound, only need every day coating once, the dark above wound surface of II degree also only needs about 2 times every day, and has no side effect, with the silver sulfadiazine contrast, this medicine wound surface that heals does not generally stay or stays cicatrix less, user is without fear of an attack from the rear.

Four, introduce two embodiment and two model cases below:

One, prescription 1: Rhizoma Polygoni Cuspidati 300g, Polygonum ciliinerve Nakai Ohwi. 250g, Borneolum Syntheticum 20g, Margarita powder 10g, Radix Glycyrrhizae 120g, Cera Flava 100g, Oleum Sesami 2000ml, medical ventolin is an amount of, and each Chinese medicine is pulverized, crosses 100 mesh sieves, puts into the Oleum Sesami immersion, boiled lixiviate, cooled and filtered, adding Cera Flava stirs evenly, add Borneolum Syntheticum when being cooled to 50 ℃, Margarita powder, an amount of medical ventolin stir into ointment, pack at last, sterilizing is finished product.

Two, prescription 2: Rhizoma Polygoni Cuspidati 250g, Polygonum ciliinerve Nakai Ohwi. 320g, Borneolum Syntheticum 10g, Margarita powder 20g, Radix Glycyrrhizae 80g, Cera Flava 150g, Oleum Sesami 1500ml, medical ventolin is an amount of, by the method preparation of prescription 1.

Case one: Yang Jiamin, the woman, 3 years old, Jinshi City Xinzhou, Hunan people from town was because of liquid fuel flame cause injury trunk and extremity.Before being admitted to hospital, surplus the thirsty anuria 10 hour, accompanied drowsiness 4 hours, the outer court changed treatment on October 12nd, 1999.Have a medical check-up: T39 ℃, P160 time/minute, R25 time/minute, Bp does not survey, and the burn severe disease holds, and grows good, nutrition is medium, staring spells, and the skin sclera does not have xanthochromia, before and after trunk, the extremity blister that differs in size, the part beancurd sheet falls to losing, pain is insensitive, clinical diagnosis is: large-area burns 38% body surface area (TBSA), hypovolemic shock, systemic infection, electrolyte disturbance and acidosis, hypoproteinemia.With the burn cream of reconstructing of prescription 1, change dressings once whole body therapeutic every day after being admitted to hospital: resisted brokenly antiinflammatory, fluid infusion recovery, entangle treatments such as acid, nutritional support 25 days, wound surface all heals.

Case 2: bright so-and-so, the man, 51 years old, be admitted to hospital in JIUYUE in 1998 emergency treatment on the 13rd in petrol burn whole body many places.AD: burn such as face, neck, two upper limb, trunk 35% body surface area (TBSA), deep burn 25%, compensatory phase of hypovolemic shock, through tetanus, antiinflammatory, fluid infusion etc., with the burn cream treatment of reconstructing of prescription 2, change dressings every day once simultaneously, logotype 35 days, wound surface is more left hospital entirely.

Claims (2)

1. burn cream of reconstructing, it is characterized in that: this ointment for treating burn is made up of the herbal raw material of following weight proportioning: Rhizoma Polygoni Cuspidati 250～300 grams, Polygonum ciliinerve Nakai Ohwi. 250～320 grams, Borneolum Syntheticum 10～20 grams, Margarita powder 10～20 grams, Radix Glycyrrhizae 80～120 grams, Cera Flava 100～150 grams, Oleum Sesami 1500～2000ml.

2. the method for preparing the described burn cream of reconstructing of claim 1, it is characterized in that: this ointment is through getting the raw materials ready, pulverize and soaking 20～30 hours with Oleum Sesami behind 100 mesh sieves excessively, and the reuse double boiler boiled 30～60 minutes, was cooled to below 80 ℃, remove fiber impurity with filtered through gauze, must contain the Oleum Sesami liquid 800～1000ml of former medicine, add Cera Flava again and stir evenly, when being cooled to 50 ℃, add Borneolum Syntheticum, Margarita powder and stir into the ointment shape with an amount of medical ventolin, cobalt (CO is used in the collapsible tube of packing into then and sealing at last ⁶⁰) irradiation sterilization, be this burn cream after detection bacterium amount is qualified.