CN1205887A

CN1205887A - Pain relieving ointment

Info

Publication number: CN1205887A
Application number: CN 97112864
Authority: CN
Inventors: 刘灵
Original assignee: Individual
Current assignee: Individual
Priority date: 1997-07-20
Filing date: 1997-07-20
Publication date: 1999-01-27

Abstract

Pain relieving ointment is a medicine preparation of plant material. It is prepared with over 20 kinds of Chinese herbal medicine materials including ephedra, Herba Asari, notopterygium, rhubarb, Radix aconiti, etc. in certain proportion and through certain extraction process and compounding with proper amount of supplementary material. Clinical application shows that it has special cure effect to traumatic injury, obvious cure effect to rheumatic lumbago and leg pain, pain shoulder and neck, hyperosteogeny, etc. and no toxic side effect and bad reaction.

Description

ZHITONG GAO

The invention belongs to a kind of medicinal preparation of making external use plaster with the vegetable crude drug raw material.

The traditional Chinese medical science thinks that people's bodily pain disease is many to cause because of qi depression to blood stasis, grain are obstructed, and outer damage of skin and superficial muscles muscles and bones, interior blepharoptosis cold-damp numbness all will make patient's pain onset.It is the subject of putting into practice of a clinical verification that the application Chinese medicine preparation carries out the treatment of pain disease to human body.The Chinese patent publication number is: " congex " of CM1117390A serves as that main prescription has carried out processing system to drug toxicity and handles by a kind of process Scorpio, Bombyx Batryticatus(processed), Eupolyphaga Seu Steleophaga with Olibanum (processed), Myrrha (processed), Herba Ephedrae (processed), Semen Strychni(processed), Radix Aconiti Preparata and animality of clinical proposition, this is a kind of rheumatoid of oral administration and externally to simple property of carrying out simultaneously, and rheumatism carries out the prescription of pain disease treatment.The Chinese patent publication number be CN1116935A's " analgesic plaster " then be a kind of with giving birth to Aconitum carmichjaelii Debx., Rhizoma Arisaematis, giving birth to the direct pulverize of Scorpio, Eupolyphaga Seu Steleophaga of Rhizoma Typhonii, Rhizoma Drynariae, Herba speranskiae tuberculatae, Galla Chinensis and animality, cross 60 mesh sieves, place the external use plaster prescription on the adhesive plaster (or non-woven fabrics), this prescription belongs to a kind of analgetic preparation that has the animal raw materials of certain proportion degree, prescription is general, and clinical analgesic resultant effect is not remarkable.

No matter the purpose of this invention is to provide the pain disease cause of disease clear and definite (external force wounds) or pain disease etiology unknown really (inner pathological changes), and can both make bitterly disease obtain a kind of of Comprehensive Treatment to make the human body externally-used pain-relieving cream of the pure vegetable crude drug extract of Transdermal absorption to greatest extent.

The present invention is achieved in that vegetable crude drug raw material Herba Ephedrae, Herba Asari, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Aconiti, Radix Aconiti Kusnezoffii, Folium Artemisiae Argyi, Rhizoma Chuanxiong, Flos Carthami, Radix Clematidis, Folium Perillae, Radix Et Rhizoma Rhei, Herba Lycopodii, Rhizoma Pinelliae, Herba Artemisiae Anomalae, Herba Taraxaci, Radix Gentianae Macrophyllae, thorn apple, the deep tip, Caulis Sargentodoxae, Herba Achilleae, Mentholum, Camphora is filled a prescription in proportion, the percentage by weight of its vegetable crude drug material content is a Herba Ephedrae 5, Herba Asari 3.3, Rhizoma Et Radix Notopterygii 3.3, Radix Angelicae Pubescentis 3.3, Radix Aconiti 3.3, Radix Aconiti Kusnezoffii 3.3, Folium Artemisiae Argyi 5, Rhizoma Chuanxiong 3.3, Flos Carthami 3.3, Radix Clematidis 3.3, Folium Perillae 5, Radix Et Rhizoma Rhei 5, Herba Lycopodii 5, give birth to half tall building 3.3, Herba Artemisiae Anomalae 5, Herba Taraxaci 5, Radix Gentianae Macrophyllae 3.3, Flos Daturae 3.3, the deep tip 5, Caulis Sargentodoxae 5, Herba Achilleae 3.3, Mentholum 3.3, Camphora 2, form pure vegetable crude drug extract through certain processing technology, be equipped with appropriate amount of auxiliary materials and make.

The present invention from the theory of Chinese medical science of traditional blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, dispelling cold by warming the meridian, expelling wind and removing dampness, screen pure natural plant and form produce effects pain relieving proved recipe efficiently.Through clinical verification, this medicine penetration is strong, treatment traumatic injury, breast side of body sprain and contusion wound, extremity soft tissue injury there are specially good effect, evident in efficacy to pain diseases such as rheumatic lumbago and scelalgia, arthralgia, shoulder and neck, hyperosteogeny pains, stochastic sampling clinical trial observation of curative effect, total effective rate is more than 95%, total obvious effective rate is more than 85%, and without any side effects and untoward reaction, and this proved recipe medicine source is abundant, with low cost, be specially adapted to extensive patients and generally use.

Most preferred embodiment of the present invention is for getting Herba Ephedrae 30g, Herba Asari 20g, each 20g of Qiang's Radix Angelicae Pubescentis, living each 20g of Radix Aconiti, Folium Artemisiae Argyi 30g, Folium Perillae 30g, Rhizoma Chuanxiong 20g, Flos Carthami 20g, Radix Clematidis 20g, Radix Et Rhizoma Rhei 30g, Herba Lycopodii 30g, giving birth to half tall building 20g, Herba Artemisiae Anomalae 30g, Herba Taraxaci 30g, Radix Gentianae Macrophyllae 20g, Flos Daturae 20g, deep tip 30g, Caulis Sargentodoxae 30g, Herba Achilleae 20g, Mentholum 20g, Camphora 10g.

Its medical preparation adopts acid alcohol hot reflux circulation extracting solution to reclaim alcohol to the former medicine component of clear paste clean, that make relative density, wherein Pei Fang the deep tip, Caulis Sargentodoxae, Herba Achilleae, Mentholum, Camphora were made the former medicine component of dust of 100 mesh sieves through pulverizing, and with the acrylic pressure sensitive gel matrix that contains penetration enhancers by the preparation of 1: 1.5: 4 drug component, it is fabulous to form the dermal osmosis effect, and can keep the active substance of high property of medicine Transdermal absorption with steady statue for a long time, and depend on movably sark layer (for example non-woven fabrics) and constitute standby stand cream.

As required ZHITONG GAO is affixed on the affected part during use.This plaster is moderate to the human body bonding force, good permeability, the long-time subsides with the four seasons all do not have dermatitis or allergic symptom, paste repeatedly and do not subtract with a plaster viscosity, use the back medicated clothing or skin is pollution-free, drug releasing rate is fast, Transdermal absorption is good, invigorate blood circulation, blood stasis dispelling, antiinflammatory, pain relieving instant effect, both be applicable to that external force hindered acute stage and handle, be applicable to inner slow-release period treatment again.

Claims

1, a kind ofly make the medical ZHITONG GAO of external use plaster with the vegetable crude drug raw material, it is characterized in that: vegetable crude drug raw material Herba Ephedrae, Herba Asari, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Aconiti, Radix Aconiti Kusnezoffii, Folium Artemisiae Argyi, Rhizoma Chuanxiong, Flos Carthami, Radix Clematidis, Folium Perillae, Radix Et Rhizoma Rhei, Herba Lycopodii, Rhizoma Pinelliae, Herba Artemisiae Anomalae, Herba Taraxaci, Radix Gentianae Macrophyllae, Flos Daturae, the deep tip, Caulis Sargentodoxae, Herba Achilleae, Mentholum, Camphora are filled a prescription in proportion.

2, ZHITONG GAO as claimed in claim 1 is characterized in that: the percentage by weight of vegetable crude drug material content is Herba Ephedrae 5, Herba Asari 3.3, Rhizoma Et Radix Notopterygii 3.3, Radix Angelicae Pubescentis 3.3, Radix Aconiti 3.3, Radix Aconiti Kusnezoffii 3.3, Folium Artemisiae Argyi 5, Rhizoma Chuanxiong 3.3, Flos Carthami 3.3, Radix Clematidis 3.3, Folium Perillae 5, Radix Et Rhizoma Rhei 5, Herba Lycopodii 5, Rhizoma Pinelliae 3.3, Herba Artemisiae Anomalae 5, Herba Taraxaci 5, Radix Gentianae Macrophyllae 3.3, Flos Daturae 3.3, the deep tip 5, Caulis Sargentodoxae 5, Herba Achilleae 3.3, Mentholum 3.3, Camphora 2.

3, as claim 1,2 described ZHITONG GAO, it is characterized in that: medical preparation adopts acid alcohol hot reflux circulation extracting solution to reclaim alcohol to clean, make the former medicine component of clear paste of relative density, Pei Fang the deep tip wherein, Caulis Sargentodoxae, Herba Achilleae, Mentholum, Camphora was made the former medicine component of dust of 100 mesh sieves through pulverizing, and with the acrylic pressure sensitive gel matrix that contains penetration enhancers by the preparation of 1: 1.5: 4 drug component, it is fabulous to form the dermal osmosis effect, and can keep the active substance of high property of medicine Transdermal absorption with steady statue for a long time, and depend on sark layer movably and the preparation method that constitutes.