CN102017968A - Bactericidal composite containing metconazole and thiocarbamate compounds - Google Patents
Bactericidal composite containing metconazole and thiocarbamate compounds Download PDFInfo
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- CN102017968A CN102017968A CN2010106071534A CN201010607153A CN102017968A CN 102017968 A CN102017968 A CN 102017968A CN 2010106071534 A CN2010106071534 A CN 2010106071534A CN 201010607153 A CN201010607153 A CN 201010607153A CN 102017968 A CN102017968 A CN 102017968A
- Authority
- CN
- China
- Prior art keywords
- metconazole
- days
- dispenser
- mancozeb
- zineb
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000005868 Metconazole Substances 0.000 title claims abstract description 111
- XWPZUHJBOLQNMN-UHFFFAOYSA-N metconazole Chemical compound C1=NC=NN1CC1(O)C(C)(C)CCC1CC1=CC=C(Cl)C=C1 XWPZUHJBOLQNMN-UHFFFAOYSA-N 0.000 title claims abstract description 111
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 26
- 239000002131 composite material Substances 0.000 title abstract description 11
- 150000003558 thiocarbamic acid derivatives Chemical class 0.000 title abstract 2
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims abstract description 58
- 239000005802 Mancozeb Substances 0.000 claims abstract description 31
- 239000005823 Propineb Substances 0.000 claims abstract description 29
- 239000011717 all-trans-retinol Substances 0.000 claims abstract description 29
- 235000019169 all-trans-retinol Nutrition 0.000 claims abstract description 29
- KKMLIVYBGSAJPM-UHFFFAOYSA-L propineb Chemical compound [Zn+2].[S-]C(=S)NC(C)CNC([S-])=S KKMLIVYBGSAJPM-UHFFFAOYSA-L 0.000 claims abstract description 29
- -1 polyram Chemical compound 0.000 claims abstract description 21
- 239000000203 mixture Substances 0.000 claims description 34
- AMHNZOICSMBGDH-UHFFFAOYSA-L zineb Chemical compound [Zn+2].[S-]C(=S)NCCNC([S-])=S AMHNZOICSMBGDH-UHFFFAOYSA-L 0.000 claims description 26
- 201000010099 disease Diseases 0.000 abstract description 31
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 31
- 239000003899 bactericide agent Substances 0.000 abstract description 6
- GNVMUORYQLCPJZ-UHFFFAOYSA-M Thiocarbamate Chemical compound NC([S-])=O GNVMUORYQLCPJZ-UHFFFAOYSA-M 0.000 abstract 1
- 230000005923 long-lasting effect Effects 0.000 abstract 1
- 230000000361 pesticidal effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 36
- 230000003449 preventive effect Effects 0.000 description 29
- 239000000839 emulsion Substances 0.000 description 22
- 239000000843 powder Substances 0.000 description 20
- 238000000034 method Methods 0.000 description 19
- 230000000694 effects Effects 0.000 description 18
- 230000002195 synergetic effect Effects 0.000 description 17
- 238000012360 testing method Methods 0.000 description 16
- 241000209140 Triticum Species 0.000 description 14
- 235000021307 Triticum Nutrition 0.000 description 14
- 238000010790 dilution Methods 0.000 description 14
- 239000012895 dilution Substances 0.000 description 14
- 239000000575 pesticide Substances 0.000 description 13
- 238000005507 spraying Methods 0.000 description 13
- 238000009736 wetting Methods 0.000 description 11
- 150000001875 compounds Chemical class 0.000 description 10
- 230000001018 virulence Effects 0.000 description 10
- 239000004563 wettable powder Substances 0.000 description 10
- 239000000725 suspension Substances 0.000 description 9
- 239000004562 water dispersible granule Substances 0.000 description 9
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 8
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 8
- 241000233679 Peronosporaceae Species 0.000 description 8
- 230000000855 fungicidal effect Effects 0.000 description 8
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 8
- 231100000820 toxicity test Toxicity 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 7
- 229920001296 polysiloxane Polymers 0.000 description 7
- 239000000126 substance Substances 0.000 description 7
- 239000011701 zinc Substances 0.000 description 7
- 241000196324 Embryophyta Species 0.000 description 6
- 239000000417 fungicide Substances 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 6
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 5
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 description 5
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 5
- 229920002472 Starch Polymers 0.000 description 5
- 239000007859 condensation product Substances 0.000 description 5
- 239000008367 deionised water Substances 0.000 description 5
- 229910021641 deionized water Inorganic materials 0.000 description 5
- NVVZQXQBYZPMLJ-UHFFFAOYSA-N formaldehyde;naphthalene-1-sulfonic acid Chemical compound O=C.C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1 NVVZQXQBYZPMLJ-UHFFFAOYSA-N 0.000 description 5
- 229920005646 polycarboxylate Polymers 0.000 description 5
- 239000008107 starch Substances 0.000 description 5
- 235000019698 starch Nutrition 0.000 description 5
- 239000005995 Aluminium silicate Substances 0.000 description 4
- 240000008067 Cucumis sativus Species 0.000 description 4
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 4
- 241000221785 Erysiphales Species 0.000 description 4
- 229920001732 Lignosulfonate Polymers 0.000 description 4
- 239000002202 Polyethylene glycol Substances 0.000 description 4
- 206010039509 Scab Diseases 0.000 description 4
- 240000003377 Shepherdia canadensis Species 0.000 description 4
- 235000018324 Shepherdia canadensis Nutrition 0.000 description 4
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 4
- 150000004996 alkyl benzenes Chemical class 0.000 description 4
- 235000012211 aluminium silicate Nutrition 0.000 description 4
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 4
- 210000000481 breast Anatomy 0.000 description 4
- 239000011575 calcium Substances 0.000 description 4
- 229910052791 calcium Inorganic materials 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 238000009313 farming Methods 0.000 description 4
- 235000011187 glycerol Nutrition 0.000 description 4
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- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 4
- 229920001223 polyethylene glycol Polymers 0.000 description 4
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 4
- 229910052725 zinc Inorganic materials 0.000 description 4
- 241000223600 Alternaria Species 0.000 description 3
- 206010059866 Drug resistance Diseases 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- 241000233866 Fungi Species 0.000 description 3
- 240000007594 Oryza sativa Species 0.000 description 3
- 235000007164 Oryza sativa Nutrition 0.000 description 3
- 235000014443 Pyrus communis Nutrition 0.000 description 3
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 3
- 239000013543 active substance Substances 0.000 description 3
- 239000003905 agrochemical Substances 0.000 description 3
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 3
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 3
- 235000011130 ammonium sulphate Nutrition 0.000 description 3
- 239000000440 bentonite Substances 0.000 description 3
- 229910000278 bentonite Inorganic materials 0.000 description 3
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 3
- LLEMOWNGBBNAJR-UHFFFAOYSA-N biphenyl-2-ol Chemical compound OC1=CC=CC=C1C1=CC=CC=C1 LLEMOWNGBBNAJR-UHFFFAOYSA-N 0.000 description 3
- 150000007942 carboxylates Chemical class 0.000 description 3
- 239000013530 defoamer Substances 0.000 description 3
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 3
- 239000002270 dispersing agent Substances 0.000 description 3
- 235000013399 edible fruits Nutrition 0.000 description 3
- 239000003995 emulsifying agent Substances 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 230000001681 protective effect Effects 0.000 description 3
- 235000009566 rice Nutrition 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
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- 239000004094 surface-active agent Substances 0.000 description 3
- 239000000375 suspending agent Substances 0.000 description 3
- 235000013311 vegetables Nutrition 0.000 description 3
- 239000000080 wetting agent Substances 0.000 description 3
- YTOPFCCWCSOHFV-UHFFFAOYSA-N 2,6-dimethyl-4-tridecylmorpholine Chemical compound CCCCCCCCCCCCCN1CC(C)OC(C)C1 YTOPFCCWCSOHFV-UHFFFAOYSA-N 0.000 description 2
- DMAXMXPDVWTIRV-UHFFFAOYSA-N 2-(2-phenylethyl)phenol Chemical compound OC1=CC=CC=C1CCC1=CC=CC=C1 DMAXMXPDVWTIRV-UHFFFAOYSA-N 0.000 description 2
- FRXSZNDVFUDTIR-UHFFFAOYSA-N 6-methoxy-1,2,3,4-tetrahydroquinoline Chemical compound N1CCCC2=CC(OC)=CC=C21 FRXSZNDVFUDTIR-UHFFFAOYSA-N 0.000 description 2
- 241000235349 Ascomycota Species 0.000 description 2
- 241000221198 Basidiomycota Species 0.000 description 2
- 241000255789 Bombyx mori Species 0.000 description 2
- 235000002566 Capsicum Nutrition 0.000 description 2
- 240000008574 Capsicum frutescens Species 0.000 description 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 2
- 239000005977 Ethylene Substances 0.000 description 2
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 2
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 2
- 239000004698 Polyethylene Substances 0.000 description 2
- LCTONWCANYUPML-UHFFFAOYSA-N Pyruvic acid Chemical compound CC(=O)C(O)=O LCTONWCANYUPML-UHFFFAOYSA-N 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 230000008485 antagonism Effects 0.000 description 2
- 230000002528 anti-freeze Effects 0.000 description 2
- HEEYEDNZYXRUQB-UHFFFAOYSA-N benzene;carbamothioic s-acid Chemical class NC(S)=O.C1=CC=CC=C1 HEEYEDNZYXRUQB-UHFFFAOYSA-N 0.000 description 2
- 229940077388 benzenesulfonate Drugs 0.000 description 2
- 239000001390 capsicum minimum Substances 0.000 description 2
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 239000007884 disintegrant Substances 0.000 description 2
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- 229940079593 drug Drugs 0.000 description 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 2
- 230000009036 growth inhibition Effects 0.000 description 2
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 125000006353 oxyethylene group Chemical group 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 description 1
- RQOCXCFLRBRBCS-UHFFFAOYSA-N (22E)-cholesta-5,7,22-trien-3beta-ol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CCC(C)C)CCC33)C)C3=CC=C21 RQOCXCFLRBRBCS-UHFFFAOYSA-N 0.000 description 1
- LYCAIKOWRPUZTN-NMQOAUCRSA-N 1,2-dideuteriooxyethane Chemical compound [2H]OCCO[2H] LYCAIKOWRPUZTN-NMQOAUCRSA-N 0.000 description 1
- JCUDAMKYTWVICI-UHFFFAOYSA-N 4-benzyl-2,3-dimethylphenol Chemical compound C1=C(O)C(C)=C(C)C(CC=2C=CC=CC=2)=C1 JCUDAMKYTWVICI-UHFFFAOYSA-N 0.000 description 1
- OQMZNAMGEHIHNN-UHFFFAOYSA-N 7-Dehydrostigmasterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CC(CC)C(C)C)CCC33)C)C3=CC=C21 OQMZNAMGEHIHNN-UHFFFAOYSA-N 0.000 description 1
- GIYOYTQPIBIOOJ-UHFFFAOYSA-N C(N)(=S)[Mn] Chemical compound C(N)(=S)[Mn] GIYOYTQPIBIOOJ-UHFFFAOYSA-N 0.000 description 1
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 1
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 description 1
- 229920005682 EO-PO block copolymer Polymers 0.000 description 1
- DNVPQKQSNYMLRS-NXVQYWJNSA-N Ergosterol Natural products CC(C)[C@@H](C)C=C[C@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@H]3CC[C@]12C DNVPQKQSNYMLRS-NXVQYWJNSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 1
- 241000233654 Oomycetes Species 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 206010034133 Pathogen resistance Diseases 0.000 description 1
- 240000003768 Solanum lycopersicum Species 0.000 description 1
- 244000061456 Solanum tuberosum Species 0.000 description 1
- 235000002595 Solanum tuberosum Nutrition 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 239000005864 Sulphur Substances 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 235000009754 Vitis X bourquina Nutrition 0.000 description 1
- 235000012333 Vitis X labruscana Nutrition 0.000 description 1
- 240000006365 Vitis vinifera Species 0.000 description 1
- 235000014787 Vitis vinifera Nutrition 0.000 description 1
- PTFCDOFLOPIGGS-UHFFFAOYSA-N Zinc dication Chemical compound [Zn+2] PTFCDOFLOPIGGS-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 125000002877 alkyl aryl group Chemical group 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 229960000892 attapulgite Drugs 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 238000004166 bioassay Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 150000004657 carbamic acid derivatives Chemical class 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- DKVNPHBNOWQYFE-UHFFFAOYSA-N carbamodithioic acid Chemical compound NC(S)=S DKVNPHBNOWQYFE-UHFFFAOYSA-N 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 230000035613 defoliation Effects 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000012990 dithiocarbamate Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- DNVPQKQSNYMLRS-SOWFXMKYSA-N ergosterol Chemical compound C1[C@@H](O)CC[C@]2(C)[C@H](CC[C@]3([C@H]([C@H](C)/C=C/[C@@H](C)C(C)C)CC[C@H]33)C)C3=CC=C21 DNVPQKQSNYMLRS-SOWFXMKYSA-N 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
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- HYFPVPNWNRFTMP-UHFFFAOYSA-N formic acid;manganese Chemical compound [Mn].OC=O HYFPVPNWNRFTMP-UHFFFAOYSA-N 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
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- 230000002070 germicidal effect Effects 0.000 description 1
- 230000035784 germination Effects 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 230000001665 lethal effect Effects 0.000 description 1
- YKSNLCVSTHTHJA-UHFFFAOYSA-L maneb Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S YKSNLCVSTHTHJA-UHFFFAOYSA-L 0.000 description 1
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- 229940124561 microbicide Drugs 0.000 description 1
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- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
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- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
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- 150000003839 salts Chemical class 0.000 description 1
- 235000021003 saturated fats Nutrition 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- PYODKQIVQIVELM-UHFFFAOYSA-M sodium;2,3-bis(2-methylpropyl)naphthalene-1-sulfonate Chemical compound [Na+].C1=CC=C2C(S([O-])(=O)=O)=C(CC(C)C)C(CC(C)C)=CC2=C1 PYODKQIVQIVELM-UHFFFAOYSA-M 0.000 description 1
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- 238000006365 thiocyanation reaction Methods 0.000 description 1
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- 239000013638 trimer Substances 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a bactericidal composite containing metconazole and thiocarbamate compounds, which comprises A and B, wherein A is selected from any one of the following thiocarbamate bactericides: propineb, polyram, zineb and mancozeb, and B is metconazole, weigh part ratio of A to B is 64:1-1:1. The bactericidal composite has obvious synergy, can be used for preventing various diseases and has the advantages of good safety to crops, rain wash resistance, long-lasting pesticide effect and the like.
Description
Technical field
The invention belongs to the disinfectant use in agriculture field, relate to a kind of preparation and application that contains the bactericidal composition of metconazole.
Background technology
Metconazole (tridemorph) is the morpholine series bactericidal agent.Molecular formula is C
17H
22ClN
3O, chemical name: 2,6-dimethyl-4-tridecyl morpholine.
Metconazole is a kind of broad spectrum activity systemic fungicide with protection and therapeutic action, can be absorbed by the root of plant, stem, leaf, and the plurality of plant diseases that basidiomycetes, sac fungi and imperfect fungus are caused is effective, mainly is the biosynthesis that suppresses the ergosterol of germ.
The agent of metconazole list is used for a long time, and disease is developed immunity to drugs, and causes the problem that dosage strengthens, preventive effect reduces, the lasting period shortens, and is unfavorable for environment sustainable development.And that the active ingredient of the different mechanisms of action is carried out is composite, is to delay the disease method commonly used that develops immunity to drugs, and according to the effect in the production application, judge this composite be synergistic effect or antagonism.Complex role is more significantly filled a prescription, and can obviously improve preventive effect, reduces the dosage of agricultural chemicals greatly, also can enlarge fungicidal spectrum, improves germicidal efficiency.
Summary of the invention
The objective of the invention is to propose a kind of generation or delaying drug resistance speed that can prevent disease drug resistance, the bactericidal composition that contains metconazole that use cost is low, preventive effect is good.
The inventor is by a large amount of indoor biometricses and field control effectiveness test, finds the use that is mixed within the specific limits of metconazole and dithiocarbamate fungicide unexpectedly, and diseases such as powdery mildew, anthracnose disease, rust disease, glume blight are had good synergistic effect.
The bactericidal composition that the present invention proposes contains two kinds of active components of A, B.
Active component A is selected from any one Carbamates bactericidal agent: comparatively preferred active component is Propineb, Carbatene, zineb, mancozeb.
Described Propineb (propineb), molecular formula are (C
5H
8N
2S
4Zn)
x, chemical name: acrylic bisdithiocarbamic zinc.Propineb belongs to the benzene thiocarbamates, acts on the synthetic of fungal cell wall and protein, can suppress infecting and sprouting of spore, can suppress mycelial growth simultaneously, causes its distortion, death.And this medicine contains and is easy to the zinc element that absorbed by crop, the quality that helps promoting plant growth and improve fruit.
Described Carbatene (metriam), molecular formula: (C
4H
6N
2S
4Zn) x chemical name: the co-ordination complex of two two sulphur deoxidation base formic acid manganese of ethylene and zinc ion.Carbatene is a kind of good protective fungicide, belongs to low-toxin farm chemicals.Because wide, the difficult resistance that produces of its bactericidal range, control efficiency obviously is better than other same series bactericidal agents, so consumption is a large tonnage product in the world always.Be the substitute products of present other protective fungicides; domestic most composite bactericide is all formulated with Carbatene processing; by field application in recent years; remarkable to preventing and treating effects such as pear scab, alternaria leaf spot of apple, vegetable category eqpidemic disease, downy mildew, field crop rust, steady quality, reliable.
Described zineb (zineb), molecular formula are C
4H
6N
2S
4Zn, chemical name: zinc ethylenebisdithiocarbamate.Zineb belongs to the benzene thiocarbamates; it is the protectant that a kind of foliage spray is used; to plant safety; the active ingredient chemical property is more active, easily is oxidized to different thiocyanation compound in water, to the cause of disease thalline contain-enzyme of SH base has had strong inhibitory effects; and the direct kill pathogens spore of energy; suppress the germination of spore, stop in the germ invaded plants body, but very little to the mycelial lethal effect of cause of disease in the invaded plants body.
Mancozeb (mancozeb) is the complex of maneb and zinc composition, and molecular formula is C
4H
6N
2S
4MnZn, chemical name: the complex salt of two two thiocarbamoyl manganese of ethylene and zinc.Mancozeb is the wider protective fungicide of fungicidal spectrum.It mainly is the oxidation that suppresses pyruvic acid in the thalline.Effective to multiple diseases such as the anthracnose on fruit tree, the vegetables, early blight, simultaneously its normal and systemic fungicide is mixed, and is used for the generation of delaying drug resistance.
Active component B is a metconazole.
The ratio of weight and number of A, two kinds of active components of B is 64: 1 to 1: 1, and preferred ratio of weight and number is 32: 1 to 2: 1, and preferred ratio of weight and number is 16: 1 to 2: 1.
The described bactericidal composition that contains metconazole is characterized in that: the percentage by weight of active component zineb and metconazole is 16: 1 to 2: 1, is preferably 8: 1 to 4: 1.
The described bactericidal composition that contains metconazole is characterized in that: the percentage by weight of active component Propineb and metconazole is 16: 1 to 2: 1, is preferably 8: 1 to 4: 1.
The described bactericidal composition that contains metconazole is characterized in that: the percentage by weight of active component Carbatene and metconazole is 16: 1 to 2: 1, is preferably 8: 1 to 4: 1.
The described bactericidal composition that contains metconazole is characterized in that: the percentage by weight of active component mancozeb and metconazole is 16: 1 to 2: 1, is preferably 8: 1 to 4: 1.
Amount of application when the content of active component depends on independent use in the present composition also depends on the mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, and the while is also relevant with the target fungi.Usually active weight percentage is 1～90% of a gross weight in the composition, and preferable is 10%～80%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1～70% active substance by weight, preferably is 5～50%; Solid pharmaceutical preparation contains 5～85% active substance by weight, preferably is 10～80%.
At least contain a kind of surfactant in the bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5～30% of a total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of bactericidal composition of the present invention is known in those skilled in the art: can be selected from dispersant, wetting agent, emulsifier or the defoamer one or more.According to different dosage form, can also contain disintegrant known in those skilled in the art, antifreeze etc. in the preparation.
Described dispersant is selected from alkylnaphthalene sulfonate, two (alkyl) naphthalenesulfonate formaldehyde condensation compound, naphthalene sulfonic acid-formaldehyde condensation product, aryl phenol polyoxyethylene succinate sulfonate, octylphenol polyethylene oxyethylene group ether sulfate, polycarboxylate, lignosulfonates, the phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkyl benzene sulfonate calcium salt, the naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy is phonetic, aliphatic amine polyoxyethylene is phonetic, polyoxyethylene carboxylate, during the ester polyoxyethylene is phonetic one or more.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, silkworm excrement, the soapberry powder.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, glucose, the aluminium chloride.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, the polyethylene glycol.
Described defoamer is selected from: silicone, C
8～10Aliphatic alcohols, C
10～20In saturated fat acids (as capric acid) and acid amides, silicone oil, the silicone compound one or more.
Described emulsifier is selected from: farming breast 500
#(alkyl benzene calcium sulfonate), 600
#Phosphate (phenyl phenol polyoxy ethyl ether phosphate), farming breast 400
#(benzyl dimethyl phenol polyoxy ethyl ether), farming breast 600
#(phenyl phenol polyoxy ethyl ether), Nongru-700
#(alkylphenol-formaldehyde resin polyoxy ethyl ether), farming breast 1600
#In (phenethyl phenol polyoxy ethyl polypropylene-base ether), the ethylene oxide-propylene oxide block copolymer one or more.
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, the precipitated calcium carbonate.
Composition of the present invention can be by the user before use through dilution or directly use.Its preparation can be by the preparation of common processing method, is about to active substance and after liquid flux or solid carrier mix, and adds in surfactant such as dispersant, stabilizing agent, wetting agent, emulsifier, binding agent, the defoamer etc. one or more again.
Bactericidal composition of the present invention can be processed into acceptable forms on any agricultural chemicals on demand.Wherein preferred dosage form is wetting powder, water dispersible granules, suspending agent, suspension emulsion.
Microbicide compositions of the present invention has protection concurrently, treats and roots out activity; available and many kind of crop is for example: fruit tree, wheat, paddy rice, potato, tomato, grape, various vegetables and flowers etc., the germ plant disease of preventing and treating Ascomycetes, Basidiomycetes, Oomycete and Fungi Imperfecti.Powdery mildew, anthracnose, rust, glume blight, downy mildew, eqpidemic disease, scab, spot defoliation etc. all there is good active.
Composition of the present invention has following advantage: the one, and said composition shows significant synergistic effect in certain ratio range, both improved protection effect, has reduced mu dosage and cost, has enlarged fungicidal spectrum again; The 2nd, because the mechanism of action difference of single agent in the said composition, the problem that does not have cross resistance is so the application of said composition can reach and delay drug-fast generation of pathogen and development, help to prolong the result of use of this medicament, reduce the purpose that pesticide resistance produces probability; The 3rd, improved safety, being mixed will be lower to the influence of environment, safer.
Embodiment
To further instruction of the present invention, the percentage among the embodiment all is weight percentage below in conjunction with embodiment, but the present invention is not limited thereto.
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.
Implementation of an application example one:
Active components A (A be selected from Propineb, zineb, Carbatene, the mancozeb a kind of) is composite to target germ Toxicity Determination with metconazole
Target: apple mildew, wheat rust, wheat glume blight, sigatoka.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
After the effective inhibition concentration scope of each medicament was determined in prerun, each medicament was established 5 dosage respectively by active constituent content and is handled, and established the clear water contrast.Carry out with reference to " agricultural chemicals indoor bioassay test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament the target germ.Measure colony diameter with the right-angled intersection method behind the 72h, calculate and respectively handle clean amount of growth, mycelial growth inhibition rate.
Clean amount of growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, tries to achieve virulence regression equation (y=a+bx) with method of least squares, and calculates the EC of every kind of medicament thus
50Value.Calculate the different proportioning synergy ratios (SR) of two medicaments according to the Wadley method simultaneously, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active components A (Propineb, zineb, Carbatene, mancozeb) and metconazole shared ratio in combination;
A is a kind of in the active components A (A is selected from Propineb, zineb, Carbatene, mancozeb);
B is a metconazole.
It is as shown in the table for result of the test:
Toxicity test result one
Table 1 Propineb, metconazole and composite toxicity test analysis of results table thereof to apple mildew
As shown in Table 1, Propineb, metconazole are to the EC of apple mildew
50Be respectively 21.75mg/L and 1.13mg/L.The virulence of Propineb is lower than the virulence of metconazole.Propineb and metconazole were mixed in the scope at 64: 1 to 1: 1 and all show synergistic effect, wherein synergistic effect is comparatively desirable when Propineb and metconazole weight ratio are in 32: 1 to 2: 1 scopes, and synergistic effect is the most obvious when Propineb and metconazole weight ratio are in 16: 1 to 4: 1 scopes.
Toxicity test result two
Table 2 zineb, metconazole and composite toxicity test analysis of results table thereof to wheat rust
As shown in Table 2, zineb, metconazole are to the EC of wheat rust
50Be respectively 31.57mg/L and 1.43mg/L.The virulence of zineb is lower than the virulence of metconazole.Zineb and metconazole were mixed in the scope at 64: 1 to 1: 1 and all show synergistic effect, wherein synergistic effect is comparatively desirable when zineb and metconazole weight ratio are in 32: 1 to 2: 1 scopes, and synergistic effect is the most obvious when zineb and metconazole weight ratio are in 16: 1 to 4: 1 scopes.
Toxicity test result three
Table 3 Carbatene, metconazole and composite toxicity test analysis of results table thereof to wheat glume blight
As shown in Table 1, Carbatene, metconazole are to the EC of wheat glume blight
50Be respectively 22.88mg//L and 1.09mg//L.The virulence of Carbatene is lower than the virulence of metconazole.Carbatene and metconazole were mixed in the scope at 64: 1 to 1: 1 and all show synergistic effect, wherein synergistic effect is comparatively desirable when Carbatene and metconazole weight ratio are in 16: 1 to 1: 8 scopes, and synergistic effect is the most obvious when Carbatene and metconazole weight ratio are in 16: 1 to 4: 1 scopes.
Toxicity test result four
Table 4 mancozeb, metconazole and composite toxicity test analysis of results table thereof to sigatoka
As shown in Table 1, mancozeb, metconazole are to the EC of sigatoka
50Be respectively 28.56mg/L and 1.15mg/L.The virulence of mancozeb is lower than the virulence of metconazole.Mancozeb and metconazole were mixed in the scope at 64: 1 to 1: 1 and all show synergistic effect, wherein contemporary gloomy MnZn and metconazole weight ratio in 32: 1 to 2: 1 scopes the time synergistic effect comparatively desirable, contemporary gloomy MnZn and metconazole weight ratio in 16: 1 to 4: 1 scopes the time synergistic effect the most obvious.
Implementation of an application example two:
The embodiment 1 80% mancozeb metconazole wetting powder control apple anthracnose test of pesticide effectiveness
Mancozeb 70%, metconazole 10%, polycarboxylate 5%, lauryl sodium sulfate 3%, spaonin powder 2%, white carbon add to 100%, and mixture carries out comminution by gas stream, make 80% mancozeb metconazole wetting powder.This proportioning is by 5000 times of dilution sprayings, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 3 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.7 days, 14 days control apple anthracnose effects are respectively 91.2%, 96.7% behind the medicine, 80% mancozeb wettable powder and 60g/L metconazole aqueous emulsion are according to same quadrat method, dilute 500 times and 5500 times of uses respectively, 14 days preventive effects are respectively 62.1% and 72.4% behind the medicine.
Embodiment 2 65% zineb metconazole wetting powders are prevented and treated the pear scab test of pesticide effectiveness
Zineb 64%, metconazole 1%, lignosulfonates 4%, tea are withered 4%, white carbon 10%, kaolin add to 100%, and mixture carries out comminution by gas stream, makes 65% zineb metconazole wetting powder.This proportioning is by 2000 times of dilution sprayings, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 3 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.Prevent and treat the pear scab effect in 7 days, 14 days behind the medicine and be respectively 92.3%, 96.8%, 70% Zineb wettable powder and 60g/L metconazole aqueous emulsion are according to same quadrat method, dilute 300 times and 5000 times of uses respectively, 14 days preventive effects are respectively 62.8% and 73.3% behind the medicine.
The embodiment 3 60% Carbatene metconazole wetting powders control cucumber downy mildew test of pesticide effectiveness
Carbatene 50%, metconazole 10%, alkylaryl APEO 4%, soapberry powder 4%, white carbon 12%, kaolin add to 100%, and mixture carries out comminution by gas stream, make 60% Carbatene metconazole wetting powder.This proportioning is by 4000 times of dilution sprayings, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 3 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.7 days, 14 days control cucumber downy mildew effects are respectively 91.8%, 95.6% behind the medicine, 70% thioneb wettable powder and 60g/L metconazole aqueous emulsion are according to same quadrat method, dilute 800 times and 6000 times of uses respectively, 14 days preventive effects are respectively 68.4% and 75.6% behind the medicine.
Embodiment 4 55% Propineb metconazole wetting powders control capsicum epidemic disease is imitated test
Propineb 50%, metconazole 5%, lignosulfonates 4%, lauryl sodium sulfate 4%, white carbon 9%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 55% Propineb metconazole wetting powder.This proportioning is by 3500 times of dilution sprayings, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 3 times, investigates disease index respectively in 7 days, 14 days, 30 days after the last dispenser and calculates preventive effect.7 days, 14 days control capsicum epidemic disease effects are respectively 90.7%, 95.1% behind the medicine, 80% Wettable propineb powder and 60g/L metconazole aqueous emulsion are according to same quadrat method, dilute 300 times and 1500 times of uses respectively, 14 days preventive effects are respectively 62.5% and 74.4% behind the medicine.
Embodiment 5 70% Carbatene metconazole water dispersible granules are prevented and treated the downy mildew of garpe test of pesticide effectiveness
Carbatene 60%, metconazole 10%, polycarboxylate 3%, lignosulfonates 3%, lauryl sodium sulfate 4%, aluminium chloride 2%, starch add to 100%, the mixed 70% Carbatene metconazole water dispersible granules that gets.This proportioning is by 4500 times of dilution sprayings, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 3 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.Prevent and treat the downy mildew of garpe effect in 7 days, 14 days behind the medicine and be respectively 91.2%, 95.1%, 70% thioneb wettable powder and 60g/L metconazole aqueous emulsion are according to same quadrat method, dilute 800 times and 5500 times of uses respectively, 14 days preventive effects are respectively 62.8% and 74.8% behind the medicine.
The embodiment 6 68% mancozeb metconazole water dispersible granules control cucumber downy mildew test of pesticide effectiveness
Mancozeb 64%, metconazole 4%, pelopon A 3%, polyoxyethylene carboxylate 3%, soapberry powder 4%, sodium bicarbonate 3%, starch 22%, kaolin add to 100%, the mixed 68% mancozeb metconazole water dispersible granules that gets.This proportioning is by 3500 times of dilution sprayings, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 2 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.7 days, 14 days control cucumber downy mildew effects are respectively 91.2%, 96.8% behind the medicine, 80% mancozeb wettable powder and 60g/L metconazole aqueous emulsion are according to same quadrat method, dilute 300 times and 5500 times of uses respectively, 14 days preventive effects are respectively 64.3% and 74.6% behind the medicine.
Embodiment 7 80% zineb metconazole water dispersible granules are prevented and treated the wheat rust test of pesticide effectiveness
Zineb 60%, metconazole 20%, alkyl benzene sulfonate calcium salt 3%, sodium phosphate trimer 3%, wetting and penetrating agent F 3%, ammonium sulfate 2%, starch add to 100%, the mixed 80% zineb metconazole water dispersible granules that gets.This proportioning is by 5000 times of dilution sprayings, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 2 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.Prevent and treat the wheat rust effect in 7 days, 14 days behind the medicine and be respectively 91.7%, 95.8%, 70% Zineb wettable powder and 60g/L metconazole aqueous emulsion are according to same quadrat method, dilute 300 times and 5000 times of uses respectively, 14 days preventive effects are respectively 65.4% and 72.1% behind the medicine.
Embodiment 8 50% Propineb metconazole water dispersible granules are prevented and treated the sigatoka test of pesticide effectiveness
Propineb 40%, metconazole 10%, octylphenol polyethylene oxyethylene group ether sulfate 3%, naphthalene sulfonic acid-formaldehyde condensation product 3%, spaonin powder 4%, ammonium sulfate 3%, starch 12%, bentonite add to 100%, the mixed 80% Propineb metconazole water dispersible granules that gets.This proportioning is by 3000 times of dilution sprayings, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 3 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.Prevent and treat the sigatoka effect in 7 days, 14 days behind the medicine and be respectively 91.7%, 96.3%, 70% Wettable propineb powder and 60g/L metconazole aqueous emulsion are according to same quadrat method, dilute 300 times and 1500 times of uses respectively, 14 days preventive effects are respectively 68.7% and 73.8% behind the medicine.
The embodiment 9 50% Propineb metconazole suspension emulsions control alternaria leaf spot of apple test of pesticide effectiveness
Propineb 45%, metconazole 5%, alkyl benzene calcium sulfonate 6%, polyoxyethylene carboxylate 4%, soapberry powder 5%, silicone compound 0.1%, hydroxyethylcellulose 0.1%, ethylene glycol 2%, deionized water add to 100%, the mixed 50% Propineb metconazole suspension emulsion that gets.This proportioning is by 3000 times of dilution sprayings, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 2 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.7 days, 14 days control alternaria leaf spot of apple effects are respectively 91.5%, 96.3% behind the medicine, 70% Wettable propineb powder and 60g/L metconazole aqueous emulsion are according to same quadrat method, dilute 300 times and 1500 times of uses respectively, 14 days preventive effects are respectively 69.5% and 73.6% behind the medicine.
The embodiment 10 33% zineb metconazole suspension emulsions control wheat glume blight test of pesticide effectiveness
Zineb 32%, metconazole 1%, phenyl phenol polyoxy ethyl ether phosphate 6%, sodium lignin sulfonate 4%, silkworm excrement 2%, silicone compound 0.1%, hydroxyethylcellulose 0.2%, propane diols 2%, deionized water add to 100%, the mixed 48% zineb metconazole suspension emulsion that gets.This proportioning is by 2000 times of dilution sprayings, and in the dispenser of wheat glume blight their early stage, dispenser in per 7 days once is total to dispenser 2 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.7 days, 14 days control wheat glume blight effects are respectively 92.6%, 96.8% behind the medicine, 70% Zineb wettable powder and 60g/L metconazole aqueous emulsion are according to same quadrat method, dilute 350 times and 1500 times of uses respectively, 14 days preventive effects are respectively 67.4% and 71.3% behind the medicine.
Embodiment 11 48% mancozeb metconazole suspension emulsions are prevented and treated the sigatoka test of pesticide effectiveness
Mancozeb 40%, metconazole 8%, sodium lignin sulfonate 3%, alkylphenol-formaldehyde resin polyoxy ethyl ether 7%, naphthalene sulfonic acid-formaldehyde condensation product 2%, draw back powder 2%, silicone compound 0.1%, polyethylene glycol 0.5%, glycerine 4%, deionized water and add to 100%, mixed 50% mancozeb metconazole suspension emulsion.This proportioning is by 3000 times of dilution sprayings, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 3 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.Prevent and treat the sigatoka effect in 7 days, 14 days behind the medicine and be respectively 91.4%, 96.2%, 70% mancozeb wettable powder and 60g/L metconazole aqueous emulsion are according to same quadrat method, dilute 300 times and 1600 times of uses respectively, 14 days preventive effects are respectively 67.8% and 76.4% behind the medicine.
The embodiment 12 20% Carbatene metconazole suspension emulsions control wheat powdery mildew test of pesticide effectiveness
Carbatene 10%, metconazole 10%, polycarboxylate 2%, phenethyl phenol polyoxy ethyl polypropylene-base ether 6%, lauryl sodium sulfate 2%, silicone compound 0.1%, polyethylene glycol 0.5%, glycerine 4%, deionized water add to 100%, the mixed 20% Carbatene metconazole suspension emulsion that gets.This proportioning is by 1500 times of dilution sprayings, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 2 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.7 days, 14 days control wheat powdery mildew effects are respectively 91.8%, 95.6% behind the medicine, 70% thioneb wettable powder and 60g/L metconazole aqueous emulsion are according to same quadrat method, dilute 450 times and 1500 times of uses respectively, 14 days preventive effects are respectively 65.4% and 78.2% behind the medicine.
Embodiment 13 40% mancozeb metconazole suspending agents are prevented and treated the rice sheath blight disease test of pesticide effectiveness
Mancozeb 35%, metconazole 5%, polycarboxylate 2%, sodium lignin sulfonate 2%, silicone compound 0.1%, polyethylene glycol 0.5%, glycerine 4%, deionized water add to 100%, the mixed 35% mancozeb metconazole suspending agent that gets.This proportioning is by 2500 times of dilution sprayings, and in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 2 times, investigates disease index respectively in 7 days, 14 days after the last dispenser and calculates preventive effect.Prevent and treat the rice sheath blight disease effect in 7 days, 14 days behind the medicine and be respectively 91.4%, 96.1%, 80% mancozeb wettable powder and 60g/L metconazole aqueous emulsion are according to same quadrat method, dilute 400 times and 4500 times of uses respectively, 14 days preventive effects are respectively 64.4% and 73.2% behind the medicine.
In the foregoing description, the ratio of active component A and B all can be adjusted in 64: 1 to 1: 1 synergy scope, thereby forms new embodiment.
Claims (8)
1. bactericidal composition that contains metconazole and thiocarbamates compound, it is characterized in that: the ratio of weight and number of two kinds of active component A and B is 64: 1 to 1: 1, described A is selected from Propineb, Carbatene, zineb, mancozeb, and the B component is a metconazole.
2. a kind of bactericidal composition that contains metconazole according to claim 1 is characterized in that: the ratio of weight and number of A, two kinds of active components of B is 32: 1 to 2: 1.
3. according to the described bactericidal composition that contains metconazole of claim 2, it is characterized in that: the percentage by weight of active component zineb and metconazole is 16: 1 to 2: 1.
4. according to the described bactericidal composition that contains metconazole of claim 2, it is characterized in that: the ratio of weight and number of active component Propineb and metconazole is 16: 1 to 2: 1.
5. according to the described bactericidal composition that contains metconazole of claim 2, it is characterized in that: the ratio of weight and number of active component Carbatene and metconazole is 16: 1 to 2: 1.
6. according to the described bactericidal composition that contains metconazole of claim 2, it is characterized in that: the ratio of weight and number of active component mancozeb and metconazole is 16: 1 to 2: 1.
7. the bactericidal composition that contains metconazole according to claim 1 is characterized in that: wherein the effective active component content accounts for 1～85% of gross weight.
8. the bactericidal composition that contains metconazole according to claim 7 is characterized in that: wherein the effective active component content accounts for 10～80% of gross weight.
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| WO2007093535A1 (en) * | 2006-02-14 | 2007-08-23 | Basf Se | A method of using a micronutrient as safener for a triazole for controlling harmful fungi |
| CN101069511A (en) * | 2006-05-09 | 2007-11-14 | 陶氏农业科学公司 | Stabilized fungus-killing agent composition |
| CN101302217A (en) * | 2008-07-02 | 2008-11-12 | 南开大学 | Triazole compounds, preparation and use thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007093535A1 (en) * | 2006-02-14 | 2007-08-23 | Basf Se | A method of using a micronutrient as safener for a triazole for controlling harmful fungi |
| CN101069511A (en) * | 2006-05-09 | 2007-11-14 | 陶氏农业科学公司 | Stabilized fungus-killing agent composition |
| CN101302217A (en) * | 2008-07-02 | 2008-11-12 | 南开大学 | Triazole compounds, preparation and use thereof |
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Application publication date: 20110420 |