CN101152138A - Face-painting product having function of dispelling stria gravidarum and method for preparing the same - Google Patents
Face-painting product having function of dispelling stria gravidarum and method for preparing the same Download PDFInfo
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- CN101152138A CN101152138A CNA2007100612953A CN200710061295A CN101152138A CN 101152138 A CN101152138 A CN 101152138A CN A2007100612953 A CNA2007100612953 A CN A2007100612953A CN 200710061295 A CN200710061295 A CN 200710061295A CN 101152138 A CN101152138 A CN 101152138A
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- removing effect
- stretch marks
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- 238000000034 method Methods 0.000 title description 2
- 238000010422 painting Methods 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 45
- 206010040925 Skin striae Diseases 0.000 claims abstract description 37
- 239000002537 cosmetic Substances 0.000 claims abstract description 26
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 18
- 239000000203 mixture Substances 0.000 claims abstract description 11
- 101800003838 Epidermal growth factor Proteins 0.000 claims abstract description 10
- 229940116977 epidermal growth factor Drugs 0.000 claims abstract description 10
- 239000004006 olive oil Substances 0.000 claims abstract description 10
- 235000008390 olive oil Nutrition 0.000 claims abstract description 10
- VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 claims abstract description 10
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- 210000000582 semen Anatomy 0.000 claims description 25
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- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims description 8
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims description 8
- LLEMOWNGBBNAJR-UHFFFAOYSA-N biphenyl-2-ol Chemical compound OC1=CC=CC=C1C1=CC=CC=C1 LLEMOWNGBBNAJR-UHFFFAOYSA-N 0.000 claims description 8
- 239000011259 mixed solution Substances 0.000 claims description 8
- -1 octadecyl glucosides Chemical class 0.000 claims description 8
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- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 7
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims description 7
- 229920002125 Sokalan® Polymers 0.000 claims description 7
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 7
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- 239000008367 deionised water Substances 0.000 claims description 7
- 229910021641 deionized water Inorganic materials 0.000 claims description 7
- 229930182478 glucoside Natural products 0.000 claims description 7
- 150000001413 amino acids Chemical class 0.000 claims description 6
- 239000003637 basic solution Substances 0.000 claims description 6
- 229940119170 jojoba wax Drugs 0.000 claims description 6
- 244000025272 Persea americana Species 0.000 claims description 5
- 235000008673 Persea americana Nutrition 0.000 claims description 5
- WYQVAPGDARQUBT-FGWHUCSPSA-N Madecassol Chemical compound O([C@@H]1[C@@H](CO)O[C@H]([C@@H]([C@H]1O)O)OC[C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O)OC(=O)[C@]12CC[C@H]([C@@H]([C@H]1C=1[C@@]([C@@]3(CC[C@H]4[C@](C)(CO)[C@@H](O)[C@H](O)C[C@]4(C)[C@H]3CC=1)C)(C)CC2)C)C)[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O WYQVAPGDARQUBT-FGWHUCSPSA-N 0.000 claims description 4
- 230000002421 anti-septic effect Effects 0.000 claims description 4
- JXSVIVRDWWRQRT-UYDOISQJSA-N asiatic acid Chemical compound C1[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CC[C@@H](C)[C@H](C)[C@H]5C4=CC[C@@H]3[C@]21C JXSVIVRDWWRQRT-UYDOISQJSA-N 0.000 claims description 4
- 229940011658 asiatic acid Drugs 0.000 claims description 4
- LBGFKBYMNRAMFC-PYSQTNCISA-N asiatic acid Natural products C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@@]34C)[C@]2(C)[C@H]1C)C(=O)O LBGFKBYMNRAMFC-PYSQTNCISA-N 0.000 claims description 4
- WYQVAPGDARQUBT-XCWYDTOWSA-N asiaticoside Natural products O=C(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@H]2[C@H](O)[C@H](O)[C@H](O[C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O3)[C@@H](CO)O2)O1)[C@@]12[C@@H]([C@@H](C)[C@H](C)CC1)C=1[C@](C)([C@@]3(C)[C@@H]([C@@]4(C)[C@H]([C@@](CO)(C)[C@@H](O)[C@H](O)C4)CC3)CC=1)CC2 WYQVAPGDARQUBT-XCWYDTOWSA-N 0.000 claims description 4
- 229940022757 asiaticoside Drugs 0.000 claims description 4
- QCYLIQBVLZBPNK-UHFFFAOYSA-N asiaticoside A Natural products O1C(C(=O)C(C)C)=CC(C)C(C2(C(OC(C)=O)CC34C5)C)C1CC2(C)C3CCC(C1(C)C)C45CCC1OC1OCC(O)C(O)C1O QCYLIQBVLZBPNK-UHFFFAOYSA-N 0.000 claims description 4
- 239000000470 constituent Substances 0.000 claims description 4
- CLXOLTFMHAXJST-UHFFFAOYSA-N esculentic acid Natural products C12CC=C3C4CC(C)(C(O)=O)CCC4(C(O)=O)CCC3(C)C1(C)CCC1C2(C)CCC(O)C1(CO)C CLXOLTFMHAXJST-UHFFFAOYSA-N 0.000 claims description 4
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- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 2
- 239000008158 vegetable oil Substances 0.000 claims description 2
- 102000008186 Collagen Human genes 0.000 abstract description 9
- 108010035532 Collagen Proteins 0.000 abstract description 9
- 235000015097 nutrients Nutrition 0.000 abstract description 4
- 230000008439 repair process Effects 0.000 abstract description 4
- 229920001436 collagen Polymers 0.000 abstract description 3
- 210000004177 elastic tissue Anatomy 0.000 abstract description 3
- 238000004519 manufacturing process Methods 0.000 abstract description 3
- 235000004626 essential fatty acids Nutrition 0.000 abstract description 2
- 235000021122 unsaturated fatty acids Nutrition 0.000 abstract description 2
- 150000004670 unsaturated fatty acids Chemical class 0.000 abstract description 2
- 244000144725 Amygdalus communis Species 0.000 abstract 1
- 235000011437 Amygdalus communis Nutrition 0.000 abstract 1
- 102000012422 Collagen Type I Human genes 0.000 abstract 1
- 108010022452 Collagen Type I Proteins 0.000 abstract 1
- 102000009024 Epidermal Growth Factor Human genes 0.000 abstract 1
- 240000006677 Vicia faba Species 0.000 abstract 1
- 235000010749 Vicia faba Nutrition 0.000 abstract 1
- 235000002098 Vicia faba var. major Nutrition 0.000 abstract 1
- 239000008168 almond oil Substances 0.000 abstract 1
- 230000003712 anti-aging effect Effects 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
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- 230000003592 biomimetic effect Effects 0.000 abstract 1
- 229940059958 centella asiatica extract Drugs 0.000 abstract 1
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Landscapes
- Cosmetics (AREA)
Abstract
The present invention relates to a cosmetic product with dispelling striae gravidarum effectiveness and a manufacturing method. Nutrient components synergy and can repair the elastic fiber effectively. Sweet almond oil and olive oil in the formula are rich in unsaturated fatty acid, which is totally identical with fats secretory of human; so essential fatty acid is added; the skin is repaired. Vitamin E has anti-aging and antioxidant effectiveness; small molecule faba bean peptide and nanometer parcel epidermal growth factor biomimetic peptide have strong physiological excitation signal which is easily absorbed by the skin; so the skin is stimulated to compose collagen which markedly amends the striae gravidarum. Centella asiatica extract can promote the composition of collagen I and III and can promote the composition of polysaccharide, which effective prevents and repairs the striae gravidarum.
Description
Technical field
The invention belongs to cosmetic field, relate to skin protection cream goods, especially a kind of cosmetic product and preparation method thereof with pregrant abdominal stretch marks-removing effect with the striae gravidarum effect of dispelling.
Background technology
Later stage of pregnancy, some waveform decorative patterns different in size can appear in women's abdominal part, divided the puerperium, took off though these decorative patterns can progressively disappear, and can stay argenteous cicatrix line-transect stricture of vagina, medically were referred to as " striae gravidarum ".In addition, the women that some are not conceived is because its acth secretion goes out a kind of glucocorticoid, perhaps because of fat-reducing or take reason such as sugared sebum steroid hormone for a long time, the skin pattern of similar striae gravidarum also can appear in abdominal part, and these striae gravidarum (or skin pattern) bring endless worry for many Mies, the especially Ms that likes to be beautiful.
By understanding, do not find to have the special-purpose cosmetic product of pregrant abdominal stretch marks-removing effect as yet.
Summary of the invention
One of purpose of the present invention provides a kind of cosmetic product of realizing dispeling striae gravidarum (skin pattern) by the mutual synergism of various nutrients such as Herba Centellae extract and biological polypeptide.
Another object of the present invention provides above-mentioned preparation method with cosmetic product of pregrant abdominal stretch marks-removing effect.
The technical scheme that the present invention takes is:
A kind of cosmetic product with pregrant abdominal stretch marks-removing effect is made of mutually A phase, B phase, C, and each mutually contained constituent and percentage by weight thereof is respectively:
A phase Semen pruni armeniacae oil 7.5～8.5%
Olive oil 5.5～6.5%
Herba Centellae extract 0.1～2.0%;
B is 16 octadecyl glucosides 2.0～2.5% mutually
Carbomer 0.08～0.09%
Glycerol 3.0～5.0%
Trehalose 2.0～2.5%
Disodiumedetate 0.04～0.06%
Triethanolamine 0.07～0.1%
Antiseptic 0.2～0.5%
Deionized water 65～75%;
C phase micromolecule Semen Viciae fabae polypeptide 1.0～4.0%
The bionical peptide 1.0～6.0% of epidermal growth factor
Vitamin grain 0.05～0.06%.
And, also can add Vegetable oil lipoprotein Jojoba oil or American Avocado Tree oil at A in mutually, the weight ratio of interpolation is 1.5～2.5%.
And, also can add vitamin E at A in mutually, the weight ratio of interpolation is 0.4～0.5%.
And, be Buddhist nun's uncle's tortoise beetle ester and/or phenyl phenol at the antiseptic described in the B phase, its weight ratio is respectively: Buddhist nun uncle tortoise beetle ester 0.15～0.20%
Phenyl phenol 0.1～0.3%.
And described Herba Centellae extract adopts high performance liquid chromatography to extract and forms, and includes Asiaticoside 37～43% and asiatic acid 57～63%, is produced by German Bayer AG.
And the micromolecule Semen Viciae fabae polypeptide of C in mutually is by the macromole polypeptide that extracts in the Semen Viciae fabae and obtains that its polypeptide molecular weight is below 1200Kda after the ferment hydrolysis.
And the skin factor bionical peptide of C in mutually is a kind of 12 amino acid whose micromolecule polypeptides that contain, and molecular weight is 1477 dalton, adopts nanotechnology to wrap up, and mean diameter is 140nm.
A kind of preparation method with cosmetic product of pregrant abdominal stretch marks-removing effect, the step of its preparation method is:
(1). by weight ratio with Semen pruni armeniacae oil, olive oil, Herba Centellae extract mix homogeneously, be heated to 80～85 ℃ afterwards, form A phase solution;
(2). by weight ratio with 16 octadecyl glucosides, carbomer, glycerol, trehalose, Buddhist nun's uncle's tortoise beetle ester and/or phenyl phenol, disodiumedetate, triethanolamine, deionized water mixing and stirring so that resin dispersion is even, be heated to 80～85 ℃ afterwards, form B phase solution;
(3). A phase solution is filtered the back add B phase solution formation mixed solution, and this mixed solution is filtered back suction vacuum still, emulsion reaction 4～6 minutes, insulation be progressively cooling after 15～25 minutes, wants evacuation, stirring in temperature-fall period; When temperature is reduced to 40～50 ℃, filter, form basic solution;
(4). in basic solution, add C phase material by weight ratio respectively---micromolecule Semen Viciae fabae peptide, the bionical peptide of epidermal growth factor, vitamin grain, mix homogeneously and discharging when temperature is reduced to 39～42 ℃, formed milky mastic is the cosmetic product finished product with pregrant abdominal stretch marks-removing effect.
And described mixed solution is in temperature-fall period, and the vacuum of institute's evacuation is 0.06mpa, and the rotating speed of stirring is 40rpm.
And, in described A phase solution, also can add Jojoba oil or American Avocado Tree oil and vitamin E.
Advantage of the present invention and good effect are:
Among the present invention the oil phase of cream with Semen pruni armeniacae oil, olive oil, dimension E etc. as basic grease, water is equipped with the compositions of preserving moisture such as glycerol, trehalose, with alkyl polyglucoside class raw material as emulsifying agent, and add micromolecule Semen Viciae fabae peptide, the bionical peptide of epidermal growth factor, and the natural plants Herba Centellae extract, common synergism.The cream series products is easier in skin absorbs, active matter mass-energy infiltration epiderm skin faster and more, and skin corium can go directly.
2. the present invention utilizes the synergistic function of various nutrients such as Herba Centellae extract and micromolecule biological polypeptide, infiltrate the Elastic tissue of skin, promote the synthetic of skin collagen protein, improve the toughness of skin, recover skin vigor and elasticity, thereby reach the purpose of dispeling striae gravidarum.Natural Herba Centellae extract wherein is a kind of known substance, its pharmacological property is distinguished to some extent because of the difference of region, the Herba Centellae of BAYER company then from the best vegetatively-Madagascar and Kenya, the employing high-efficient liquid phase chromatogram technology extracts, and is milky crystalloid powder, odorless, bitter in the mouth, the Asiaticoside that wherein contains (content 37～43%), and asiatic acid (content 57～63%), water insoluble.Herba Centellae has very long use history as conventional medicament in India, Asia, Africa, Madagascar, be mainly used in the disease of treatment skin and mucosa, be applied in the cosmetics because of its potent corium reorganization activity subsequently, make the fibroblast gene activation, impel Proteometabolism, promote collagen synthetic, increase the mucopolysaccharide secretion, have antiinflammatory simultaneously and resist all active.By test, use the repairing and nursing stria gravidarum cream that contains Herba Centellae extract 0.1～1% every day, after six months, can make the width of striae gravidarum reduce 26%, and length reduces 40%, and the striae gravidarum color weakens 50%.
3. polypeptide of the present invention is to extract from Semen Viciae fabae, and through the ferment resolution process, the aminoacid that obtains forms micromolecule polypeptide with the mode combination of peptide.The aminoacid of the approximate ser structure of micromolecule polypeptide, the molecular weight of the polypeptide of generation have excellent affinity to skin below 1200Kda, make the easier absorption of skin.After this micromolecule polypeptide infiltrates deep skin, can send out the aging signal that reverses and give collagen protein, and stimulation generates new fibroblast, make it to produce more collagen protein, promote that the supporting construction of epidermal area collagen protein is strengthened, improve skin elasticity, improve striae gravidarum.
4. the bionical peptide of the skin factor of nano-encapsulated of the present invention, contain 12 amino acid whose micromolecule polypeptides for a kind of, molecular weight is 1477 dalton, adopt nanotechnology to wrap up, average nanometer particle size is 140nm, can arrive the epidermal area and the skin corium of skin, promote the growth of horn cell and fibroblast, increase cell adhesion, increase collagen protein in horn cell and the fibroblast and hyaluronic synthetic, effectively improve and repair striae gravidarum.
5. the component nutrient synergism among the present invention can effectively be repaired elastic fiber.Wherein the Semen pruni armeniacae oil in the prescription, olive oil contain abundant unsaturated fatty acid, and be in full accord with human fat secretion gland, replenishes essential fatty acid, repairs skin; Dimension E defying age, anti-oxidation efficacy; Micromolecule Semen Viciae fabae peptide and the bionical peptide of nano-encapsulated epidermal growth factor have intensive physiological arousal signal, very easily by skin absorbs, excite skin to synthesize collagen protein, make striae gravidarum be improved significantly; Herba Centellae extract can promote the synthetic of collagen protein I and III, promotes the synthetic of mucopolysaccharide, effectively prevention and maintenance striae gravidarum.
The specific embodiment
Below in conjunction with embodiment technology contents of the present invention is described further; Following embodiment is illustrative, is not determinate, can not limit protection scope of the present invention with following embodiment.
Embodiment 1:
A kind of cosmetic product with pregrant abdominal stretch marks-removing effect is made of mutually A phase, B phase, C, and each mutually contained constituent and percentage by weight thereof is respectively:
The composition addition
A phase Semen pruni armeniacae oil 8.00%
Olive oil 6.00%
Jojoba oil 2.00%
Vitamin E 0.50%
Herba Centellae extract 0.20%
B is 16 octadecyl glucosides 2.50% mutually
Carbomer 0.08%
Glycerol 4.00%
Trehalose 2.00%
Buddhist nun uncle tortoise beetle ester 0.15%
Disodiumedetate 0.05%
Phenyl phenol 0.20%
Triethanolamine 0.08%
Deionized water 67.19%
C phase micromolecule Semen Viciae fabae peptide 3.00%
The bionical peptide 4.00% of epidermal growth factor
Vitamin grain 0.05%.
Wherein, the middle mutually Herba Centellae extract of A adopts high performance liquid chromatography to extract and forms, include Asiaticoside 37～43% and asiatic acid 57～63%, produced by German Bayer AG.
The micromolecule Semen Viciae fabae polypeptide of C in mutually is by the macromole polypeptide that extracts in the Semen Viciae fabae and obtains that its polypeptide molecular weight is below 1200Kda after the ferment hydrolysis.
The skin factor bionical peptide of C in mutually is a kind of 12 amino acid whose micromolecule polypeptides that contain, and molecular weight is 1477 dalton, adopts nanotechnology to wrap up, and mean diameter is 140nm.
The vitamin grain of C in mutually is outside for cellulose and be enclosed with the spherical particle of vitamin E in it, is the commercially available prod.
A kind of preparation method with cosmetic product of pregrant abdominal stretch marks-removing effect, the step of its preparation method is:
(1). by weight ratio with Semen pruni armeniacae oil, olive oil, Jojoba oil, vitamin E, Herba Centellae extract mix homogeneously, be heated to 80 ℃ afterwards, form A phase solution;
(2). by weight ratio with 16 octadecyl glucosides, carbomer, glycerol, trehalose, Buddhist nun uncle tortoise beetle ester, disodiumedetate, phenyl phenol, triethanolamine, deionized water mixing and stirring so that resin dispersion is even, be heated to 80 ℃ afterwards, form B phase solution;
(3). A phase solution is filtered the back add B phase solution formation mixed solution, and with this mixed solution filtration back suction vacuum still, emulsion reaction 5 minutes, insulation be progressively cooling after 20 minutes, wants evacuation in temperature-fall period, the vacuum of evacuation is 0.06mpa, stirs under the 40rpm rotating speed; When temperature is reduced to 45 ℃, filter, form basic solution;
(4). in basic solution, add C phase material by weight ratio respectively---micromolecule Semen Viciae fabae peptide, the bionical peptide of epidermal growth factor, vitamin grain, mix homogeneously and discharging when temperature is reduced to 40 ℃, formed milky mastic is the cosmetic product finished product with pregrant abdominal stretch marks-removing effect.
Embodiment 2:
A kind of cosmetic product with pregrant abdominal stretch marks-removing effect is made of mutually A phase, B phase, C, and each mutually contained constituent and percentage by weight thereof is respectively:
The composition addition
A phase Semen pruni armeniacae oil 8.20%
Olive oil 5.50%
American Avocado Tree oil 2.10%
Vitamin E 0.40%
Herba Centellae extract 1.20%
B is 16 octadecyl glucosides 2.10% mutually
Carbomer 0.09%
Glycerol 3.00%
Trehalose 2.50%
Buddhist nun uncle tortoise beetle ester 0.20%
Disodiumedetate 0.04%
Triethanolamine 0.07%
Deionized water 69.54%
C phase micromolecule Semen Viciae fabae peptide 2.00%
The bionical peptide 3.00% of epidermal growth factor
Vitamin grain 0.06%.
Other are same as embodiment 1.
Its preparation method is same as embodiment 1.
Claims (10)
1. cosmetic product with pregrant abdominal stretch marks-removing effect is characterized in that: be made of mutually A phase, B phase, C, each mutually contained constituent and percentage by weight thereof is respectively:
A phase Semen pruni armeniacae oil 7.5～8.5%
Olive oil 5.5～6.5%
Herba Centellae extract 0.1～2.0%;
B is 16 octadecyl glucosides 2.0～2.5% mutually
Carbomer 0.08～0.09%
Glycerol 3.0～5.0%
Trehalose 2.0～2.5%
Disodiumedetate 0.04～0.06%
Triethanolamine 0.07～0.1%
Antiseptic 0.2～0.5%
Deionized water 65～75%;
C phase micromolecule Semen Viciae fabae polypeptide 1.0～4.0%
The bionical peptide 1.0～6.0% of epidermal growth factor
Vitamin grain 0.05～0.06%.
2. a kind of cosmetic product with pregrant abdominal stretch marks-removing effect according to claim 1 is characterized in that: also can add Vegetable oil lipoprotein Jojoba oil or American Avocado Tree oil at A in mutually, the weight ratio of interpolation is 1.5～2.5%.
3. a kind of cosmetic product with pregrant abdominal stretch marks-removing effect according to claim 1 is characterized in that: also can add vitamin E at A in mutually, the weight ratio of interpolation is 0.4～0.5%.
4. a kind of cosmetic product with pregrant abdominal stretch marks-removing effect according to claim 1 is characterized in that: be Buddhist nun's uncle's tortoise beetle ester and/or phenyl phenol at the antiseptic described in the B phase, its weight ratio is respectively: Buddhist nun uncle tortoise beetle ester 0.15～0.20%
Phenyl phenol 0.1～0.3%.
5. a kind of cosmetic product according to claim 1 with pregrant abdominal stretch marks-removing effect, it is characterized in that: described Herba Centellae extract adopts high performance liquid chromatography to extract and forms, include Asiaticoside 37～43% and asiatic acid 57～63%, produce by German Bayer AG.
6. a kind of cosmetic product with pregrant abdominal stretch marks-removing effect according to claim 1 is characterized in that: the micromolecule Semen Viciae fabae polypeptide of C in mutually is by the macromole polypeptide that extracts in the Semen Viciae fabae and obtains that its polypeptide molecular weight is below 1200Kda after the ferment hydrolysis.
7. a kind of cosmetic product according to claim 1 with pregrant abdominal stretch marks-removing effect, it is characterized in that: the skin factor bionical peptide of C in mutually is a kind of 12 amino acid whose micromolecule polypeptides that contain, molecular weight is 1477 dalton, adopts nanotechnology to wrap up, and mean diameter is 140nm.
8. preparation method with cosmetic product of pregrant abdominal stretch marks-removing effect as claimed in claim 1 is characterized in that:
The step of preparation method is:
(1). by weight ratio with Semen pruni armeniacae oil, olive oil, Herba Centellae extract mix homogeneously, be heated to 80～85 ℃ afterwards, form A phase solution;
(2). by weight ratio with 16 octadecyl glucosides, carbomer, glycerol, trehalose, Buddhist nun's uncle's tortoise beetle ester and/or phenyl phenol, disodiumedetate, triethanolamine, deionized water mixing and stirring so that resin dispersion is even, be heated to 80～85 ℃ afterwards, form B phase solution;
(3). A phase solution is filtered the back add B phase solution formation mixed solution, and this mixed solution is filtered back suction vacuum still, emulsion reaction 4～6 minutes, insulation be progressively cooling after 15～25 minutes, wants evacuation, stirring in temperature-fall period; When temperature is reduced to 40～50 ℃, filter, form basic solution;
(4). in basic solution, add C phase material by weight ratio respectively---micromolecule Semen Viciae fabae peptide, the bionical peptide of epidermal growth factor, vitamin grain, mix homogeneously and discharging when temperature is reduced to 39～42 ℃, formed milky mastic is the cosmetic product finished product with pregrant abdominal stretch marks-removing effect.
9. a kind of preparation method with cosmetic product of pregrant abdominal stretch marks-removing effect according to claim 8 is characterized in that: described mixed solution is in temperature-fall period, and the vacuum of institute's evacuation is 0.06mpa, and the rotating speed of stirring is 40rpm.
10. a kind of preparation method with cosmetic product of pregrant abdominal stretch marks-removing effect according to claim 8 is characterized in that: also can add Jojoba oil or American Avocado Tree oil and vitamin E in described A phase solution.
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| CN2007100612953A CN101152138B (en) | 2007-09-29 | 2007-09-29 | Face-painting product having function of dispelling stria gravidarum and method for preparing the same |
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| CN2007100612953A CN101152138B (en) | 2007-09-29 | 2007-09-29 | Face-painting product having function of dispelling stria gravidarum and method for preparing the same |
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