CN110327264A - The effectively Recipe and preparation method of desalination striae of pregnancy - Google Patents
The effectively Recipe and preparation method of desalination striae of pregnancy Download PDFInfo
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- CN110327264A CN110327264A CN201910732280.8A CN201910732280A CN110327264A CN 110327264 A CN110327264 A CN 110327264A CN 201910732280 A CN201910732280 A CN 201910732280A CN 110327264 A CN110327264 A CN 110327264A
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- China
- Prior art keywords
- pregnancy
- striae
- desalination
- composition according
- mixture
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Links
- 206010040925 Skin striae Diseases 0.000 title claims abstract description 54
- 230000035935 pregnancy Effects 0.000 title claims abstract description 54
- 238000010612 desalination reaction Methods 0.000 title claims abstract description 26
- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- 239000000203 mixture Substances 0.000 claims abstract description 60
- 230000000694 effects Effects 0.000 claims abstract description 19
- 239000002994 raw material Substances 0.000 claims abstract description 14
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 9
- 239000004909 Moisturizer Substances 0.000 claims abstract description 7
- 239000003963 antioxidant agent Substances 0.000 claims abstract description 7
- 230000003078 antioxidant effect Effects 0.000 claims abstract description 7
- 239000004519 grease Substances 0.000 claims abstract description 7
- 230000001333 moisturizer Effects 0.000 claims abstract description 7
- 239000002562 thickening agent Substances 0.000 claims abstract description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 6
- 239000003755 preservative agent Substances 0.000 claims abstract description 5
- 230000002335 preservative effect Effects 0.000 claims abstract description 5
- 239000008367 deionised water Substances 0.000 claims abstract description 3
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 33
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims description 14
- 235000011187 glycerol Nutrition 0.000 claims description 12
- 238000003756 stirring Methods 0.000 claims description 12
- 238000010792 warming Methods 0.000 claims description 10
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims description 9
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims description 9
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 8
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 claims description 8
- 235000008390 olive oil Nutrition 0.000 claims description 8
- 239000004006 olive oil Substances 0.000 claims description 8
- 229920005573 silicon-containing polymer Polymers 0.000 claims description 8
- 235000010384 tocopherol Nutrition 0.000 claims description 8
- 239000011732 tocopherol Substances 0.000 claims description 8
- 229960001295 tocopherol Drugs 0.000 claims description 8
- 229930003799 tocopherol Natural products 0.000 claims description 8
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 8
- 239000000230 xanthan gum Substances 0.000 claims description 8
- 229920001285 xanthan gum Polymers 0.000 claims description 8
- 229940082509 xanthan gum Drugs 0.000 claims description 8
- 235000010493 xanthan gum Nutrition 0.000 claims description 8
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims description 8
- 244000146462 Centella asiatica Species 0.000 claims description 7
- 235000004032 Centella asiatica Nutrition 0.000 claims description 7
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims description 7
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 7
- 239000010931 gold Substances 0.000 claims description 7
- 229910052737 gold Inorganic materials 0.000 claims description 7
- 229960003966 nicotinamide Drugs 0.000 claims description 7
- 235000005152 nicotinamide Nutrition 0.000 claims description 7
- 239000011570 nicotinamide Substances 0.000 claims description 7
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims description 7
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims description 6
- PMMYEEVYMWASQN-DMTCNVIQSA-N Hydroxyproline Chemical compound O[C@H]1CN[C@H](C(O)=O)C1 PMMYEEVYMWASQN-DMTCNVIQSA-N 0.000 claims description 6
- 235000018936 Vitellaria paradoxa Nutrition 0.000 claims description 6
- 241001135917 Vitellaria paradoxa Species 0.000 claims description 6
- 229960003237 betaine Drugs 0.000 claims description 6
- PMMYEEVYMWASQN-UHFFFAOYSA-N dl-hydroxyproline Natural products OC1C[NH2+]C(C([O-])=O)C1 PMMYEEVYMWASQN-UHFFFAOYSA-N 0.000 claims description 6
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims description 6
- 229960002591 hydroxyproline Drugs 0.000 claims description 6
- 229940057910 shea butter Drugs 0.000 claims description 6
- FGMPLJWBKKVCDB-UHFFFAOYSA-N trans-L-hydroxy-proline Natural products ON1CCCC1C(O)=O FGMPLJWBKKVCDB-UHFFFAOYSA-N 0.000 claims description 6
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 5
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims description 5
- 229960004889 salicylic acid Drugs 0.000 claims description 5
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 5
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 5
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims description 4
- 108010020346 Polyglutamic Acid Proteins 0.000 claims description 4
- 239000004721 Polyphenylene oxide Substances 0.000 claims description 4
- 244000299461 Theobroma cacao Species 0.000 claims description 4
- 235000009470 Theobroma cacao Nutrition 0.000 claims description 4
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims description 4
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims description 4
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims description 4
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 4
- GHBFNMLVSPCDGN-UHFFFAOYSA-N caprylic acid monoglyceride Natural products CCCCCCCC(=O)OCC(O)CO GHBFNMLVSPCDGN-UHFFFAOYSA-N 0.000 claims description 4
- 229920002643 polyglutamic acid Polymers 0.000 claims description 4
- 239000002253 acid Substances 0.000 claims description 3
- 229920000570 polyether Polymers 0.000 claims description 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 2
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims description 2
- 229920002125 Sokalan® Polymers 0.000 claims description 2
- 229960000458 allantoin Drugs 0.000 claims description 2
- 229960001631 carbomer Drugs 0.000 claims description 2
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 claims description 2
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 claims description 2
- 229940074410 trehalose Drugs 0.000 claims description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims 1
- 241000283153 Cetacea Species 0.000 claims 1
- OBETXYAYXDNJHR-UHFFFAOYSA-N alpha-ethylcaproic acid Natural products CCCCC(CC)C(O)=O OBETXYAYXDNJHR-UHFFFAOYSA-N 0.000 claims 1
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 claims 1
- 229960005323 phenoxyethanol Drugs 0.000 claims 1
- 229940119485 safflower extract Drugs 0.000 claims 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims 1
- 230000006651 lactation Effects 0.000 abstract description 6
- 231100000331 toxic Toxicity 0.000 abstract description 3
- 230000002588 toxic effect Effects 0.000 abstract description 3
- 238000012360 testing method Methods 0.000 description 11
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 9
- 229940082500 cetostearyl alcohol Drugs 0.000 description 7
- OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 description 7
- 230000015572 biosynthetic process Effects 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 description 4
- 102000008186 Collagen Human genes 0.000 description 3
- 108010035532 Collagen Proteins 0.000 description 3
- 229920001436 collagen Polymers 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 description 3
- 239000002344 surface layer Substances 0.000 description 3
- 238000003786 synthesis reaction Methods 0.000 description 3
- 150000003626 triacylglycerols Chemical class 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- 102000016942 Elastin Human genes 0.000 description 2
- 108010014258 Elastin Proteins 0.000 description 2
- 102000004887 Transforming Growth Factor beta Human genes 0.000 description 2
- 108090001012 Transforming Growth Factor beta Proteins 0.000 description 2
- 230000003796 beauty Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 229920002549 elastin Polymers 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 239000003102 growth factor Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 229960000581 salicylamide Drugs 0.000 description 2
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 description 2
- 210000000689 upper leg Anatomy 0.000 description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- 208000002863 Abdominal Pregnancy Diseases 0.000 description 1
- 241000288570 Chionochloa conspicua Species 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 208000013427 abdominal ectopic pregnancy Diseases 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 210000001217 buttock Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000035606 childbirth Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- WQPDQJCBHQPNCZ-UHFFFAOYSA-N cyclohexa-2,4-dien-1-one Chemical compound O=C1CC=CC=C1 WQPDQJCBHQPNCZ-UHFFFAOYSA-N 0.000 description 1
- 235000015177 dried meat Nutrition 0.000 description 1
- 201000003511 ectopic pregnancy Diseases 0.000 description 1
- 210000004177 elastic tissue Anatomy 0.000 description 1
- 229960005150 glycerol Drugs 0.000 description 1
- 230000003054 hormonal effect Effects 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 229960004063 propylene glycol Drugs 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of desalination striae of pregnancy composition, the raw material including following parts by weight: emulsifier 2-4%, grease 5-40%, thickener 0.05-3%, moisturizer 0.05-20%, antioxidant 0.05-1%, preservative 0.2-1%, efficacy activity object 0.2-10%, deionized water surplus.A kind of desalination striae of pregnancy composition of the invention and preparation method thereof, exist for solving the problems, such as that non-lactation period has educated Ms's striae of pregnancy, and after tested statistics indicate that the composition, which has educated Ms for non-lactation period, has the effect of good desalination striae of pregnancy, there is no toxic side effect, meets the use demand of people.
Description
Technical field
The present invention relates to cosmetic technical fields, specially effectively desalinate the Recipe and preparation method of striae of pregnancy.
Background technique
With the continuous improvement of people's living standards, the Ms that likes to be beautiful is higher and higher to the perfect degree requirement of autologous skin,
The especially arrival in summer, has educated that Ms wants to wear dew waist, the hope of revealing thigh clothes is just not being met, because striae of pregnancy is deposited
?.
The formation of striae of pregnancy is mainly due to the gestational period hormonal influence, and abdominal distention makes the elastic fibers of skin in addition
It damages or is broken with collagenous fibres, skin of abdomen is thinning to attenuate, and it is different, different in size pink or purplish red some width occur
The wavy decorative pattern of color.After childbirth, these decorative patterns can fade away, and leave white or argenteous glossiness scar strain line,
That is striae of pregnancy.Striae of pregnancy mainly appears on stomach wall, it is also possible to appear in outside, buttocks, chest, rear waist and arm in thigh
Etc..Primipara is the most obvious.Once striae of pregnancy occur would not disappear.
Mainly use accumulated snow grass as raw material to striae of pregnancy position for preventing and desalinating the product of striae of pregnancy on the market at present
Skin is repaired, and collagen is promoted to accelerate synthesis, to play the role of desalination or removal striae of pregnancy.But such way compared with
It is single, striae of pregnancy cannot be acted on from the every aspect of skin, effect is not ideal enough.
Summary of the invention
The purpose of the present invention is to provide the Recipes and preparation method of effective desalination striae of pregnancy, are used for solution lactation by no means
Phase educated Ms's striae of pregnancy there are the problem of.
To achieve the above object, the invention provides the following technical scheme: a kind of desalination striae of pregnancy composition, including it is following heavy
Measure the raw material of part: emulsifier 2-4%, grease 5-40%, thickener 0.05-3%, moisturizer 0.05-20%, antioxidant
0.05-1%, preservative 0.2-1%, efficacy activity object 0.2-10%, deionized water surplus.
Preferably, the emulsifier includes one or more of emulsifier of A165, M68, M82, M202.
Preferably, the grease include olive oil, caprylic/capric triglyceride, cocoa seed rouge, dimethyl silicone polymer,
One or more of white pond flower seed oil, shea butter.
Preferably, the thickener includes one or more of xanthan gum, cetostearyl alcohol, carbomer.
Preferably, the moisturizer includes glycerol, propylene glycol, butanediol, dipropylene glycol, glycerin polyether -26, hyaluronic acid
One or more of sodium, trehalose, allantoin, polyglutamic acid, glycine betaine.
Preferably, the antioxidant includes tocopherol.
Preferably, the preservative includes 1,2- pentanediol, parahydroxyacet-ophenone, 1,2- hexylene glycol, decoyl hydroximic acid, benzene
One or more of oxyethanol, glycerol caprylate.
Preferably, the efficacy activity object includes gold sarranine flower extract, Gotu Kola P.E, salicylic acid, hydroxyl dried meat ammonia
Acid, niacinamide.
A kind of preparation method for desalinating striae of pregnancy composition, the specific steps are as follows:
Step 1: the emulsifier, grease, antioxidant are mixed and are warming up to 75-80 DEG C, obtains mixture one, it is standby
With；
Step 2: the moisturizer, thickener are mixed and are warming up to 75-80 DEG C, obtains mixture two, it is spare；
Step 3: mixture one is added in mixture two, and homogeneous 5 minutes, then low speed vacuum stirs 15 minutes,
It is cooled to 40 DEG C after stirring, obtains mixture three；
Step 4: remaining raw material being added in mixture three and is stirred evenly and is combined to get to final desalination striae of pregnancy
Object.
Preferably, the speed of homogeneous is 2500-3000rpm in the step 3, and the revolving speed of low speed vacuum stirring is 50-
70rpm, vacuum degree are -0.06Mpa~-0.08Mpa.
Preferably, cooling rate is 1 DEG C/min in the step 3.
Compared with prior art, beneficial effects of the present invention are as follows: it is extensive that the beneficial effects of the present invention are raw material sources,
Preparation process is simple.Salicylic acid and niacinamide can help striae of pregnancy skin quickly to update surface layer cuticula, make the striae of pregnancy of white
Seem less obvious.Hydroxyproline, gold sarranine flower extract, Gotu Kola P.E three can act synergistically on corium
Layer promotes the synthesis of collagen and elastin laminin, and function and effect, which can match in excellence or beauty, converts growth factor TGF-β.The composition is from skin
Skin surface layer cuticula and skin corium are started with, and are worked along both lines, after tested statistics indicate that the composition has educated Ms for non-lactation period
Have the effect of that good desalination striae of pregnancy meets the use demand of people without toxic side effect.
Detailed description of the invention
Fig. 1 is 1 material component schematic diagram of the embodiment of the present invention；
Fig. 2 is 2 material component structural schematic diagram of the embodiment of the present invention；
Fig. 3 is 3 material component structural schematic diagram of the embodiment of the present invention；
Fig. 4 is the schematic diagram of test result of the present invention.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
Referring to Fig. 1, the present invention provides embodiment 1:
A kind of composition for desalinating striae of pregnancy, the raw material including following parts by weight: water surplus, glycerol 5.0%, butanediol
3.0%, Sodium Hyaluronate 0.1%, trehalose 1.0%, xanthan gum 0.05%, M681.0%, A1652.0%, olive oil
8.0%, cocoa seed ester 2.0%, dimethyl silicone polymer 3.0%, cetostearyl alcohol 3.0%, caprylic/capric triglyceride
5.0%, white pond flower seed oil 3.0%, tocopherol 0.5%, parahydroxyacet-ophenone 0.5%, 1,2- hexylene glycol 0.5%, gold sarranine
Flower extract 0.5%, Gotu Kola P.E 0.5%, salicylic acid 0.5%, hydroxyproline 0.5%, niacinamide 3.0%.
A kind of preparation method for desalinating striae of pregnancy composition, includes the following steps:
Step 1, by A165, M68, olive oil, cocoa seed ester, dimethyl silicone polymer, cetostearyl alcohol, caprylic/capric
Triglycerides, white pond flower seed oil, tocopherol mix and are warming up to 75-80 DEG C, obtain mixture one, spare.
Step 2, glycerol, butanediol, Sodium Hyaluronate, trehalose, xanthan gum are mixed and is warming up to 75-80 DEG C, obtained
Mixture two, it is spare.
Step 3, mixture one is added in mixture two, and homogeneous 5 minutes, then low speed vacuum stirs 15 minutes,
It is cooled to 40 DEG C after stirring, obtains mixture three.
Step 4, remaining raw material is added in mixture three and is stirred evenly and combined to get to final desalination striae of pregnancy
Object.
Referring to Fig. 2, the present invention provides embodiment 2:
A kind of composition for desalinating striae of pregnancy, the raw material including following parts by weight: water surplus, glycerol 5.0%, glycerol are poly-
Ether -263.0%, polyglutamic acid 0.1%, glycine betaine 1.0%, xanthan gum 0.05%, M821.0%, A1652.0%, olive oil
5.0%, shea butter 4.0%, dimethyl silicone polymer 3.0%, cetostearyl alcohol 2.5%, caprylic/capric triglyceride
5.0%, white pond flower seed oil 5.0%, tocopherol 0.5%, 1,2- pentanediol 3.0%, 1,2- hexylene glycol 0.5%, gold safron
Extract 2.0%, Gotu Kola P.E 0.8%, salicylic acid 0.5%, hydroxyproline 0.8%, niacinamide 5.0%.
A kind of preparation method for desalinating striae of pregnancy composition, includes the following steps:
Step 1, by A165, M82, olive oil, shea butter, dimethyl silicone polymer, cetostearyl alcohol, caprylic/capric
Triglycerides, white pond flower seed oil, tocopherol mix and are warming up to 75-80 DEG C, obtain mixture one, spare.
Step 2, glycerol, glycerin polyether -26, polyglutamic acid, glycine betaine, xanthan gum are mixed and is warming up to 75-80 DEG C, obtained
It is spare to mixture two.
Step 3, mixture one is added in mixture two, and homogeneous 5 minutes, then low speed vacuum stirs 15 minutes,
It is cooled to 40 DEG C after stirring, obtains mixture three.
Step 4, remaining raw material is added in mixture three and is stirred evenly and combined to get to final desalination striae of pregnancy
Object.
Referring to Fig. 3, the present invention provides embodiment 3:
A kind of composition for desalinating striae of pregnancy, the raw material including following parts by weight: water surplus, glycerol 5.0%, propylene glycol
3.0%, Sodium Hyaluronate 0.1%, glycine betaine 1.0%, xanthan gum 0.05%, M2021.0%, A1652.0%, olive oil
5.0%, shea butter 4.0%, dimethyl silicone polymer 3.0%, cetostearyl alcohol 2.5%, caprylic/capric triglyceride
5.0%, white pond flower seed oil 5.0%, tocopherol 0.5%, 1,2- pentanediol 3.0%, 1,2- hexylene glycol 0.5%, gold safron
Extract 1.0%, Gotu Kola P.E 0.5%, salicylic acid 0.3, hydroxyproline 1.0%, niacinamide 3.0%.
A kind of preparation method for desalinating striae of pregnancy composition, includes the following steps:
Step 1, by A165, M202, olive oil, shea butter, dimethyl silicone polymer, cetostearyl alcohol, caprylic/capric
Triglycerides, white pond flower seed oil, tocopherol mix and are warming up to 75-80 DEG C, obtain mixture one, spare.
Step 2, glycerol, propylene glycol, Sodium Hyaluronate, glycine betaine, xanthan gum are mixed and is warming up to 75-80 DEG C, obtained
Mixture two, it is spare.
Step 3, mixture one is added in mixture two, and homogeneous 5 minutes, then low speed vacuum stirs 15 minutes,
It is cooled to 40 DEG C after stirring, obtains mixture three.
Step 4, remaining raw material is added in mixture three and is stirred evenly and combined to get to final desalination striae of pregnancy
Object.
The following are test process and results:
1, experiment product: embodiment 1-3；
2, crowd: 40 people is tested；
3, the age: between 25-35 years old；
4, test request: can cooperate well testing experiment, and regular uses test sample as requested, and non-lactation period is
It educates women and has obvious striae of pregnancy；
5, test method: experimenter abdominal pregnancy line position is as test area, it is specified that subject's each use sooner or later daily
Once, according to striae of pregnancy area size, appropriate amount of sample is taken uniformly to smear, until absorbing.Experimenter is divided into 4 groups, every group 10
People, 1,2,3 group of experimental group use 1,2, No. 3 sample of embodiment respectively, and 4 groups as a control group, select certain commercially available famous brand name pregnant
It is pregnent line body lotion.It tests after starting 1 week, 2 weeks, 1 month, 2 months, test result was collected in progress follow-up in 3 months；
6, effect criterion: whether effective for the effect assessment after using sample by collecting experimenter.1: effect
Obvious: striae of pregnancy lines color is obviously desalinated or obvious lines is reduced, that is, determines effective.2: effect is general: striae of pregnancy lines
There are faint desalination or the faint reduction of lines.3: invalid: test front and back is without significant change；
7, test result is shown in Fig. 4.
From test data as can be seen that after final use in 3 months, 3 groups of embodiments for desalination striae of pregnancy quantity and
The effective percentage of lines is 90% or more, and 4 groups of control group final effective percentage only rest on 60%.Illustrate to desalinate striae of pregnancy combination
The effect of object is quite obvious.It is especially optimal with the 2nd group of collocation.
Above-described embodiment is only the present invention preferably embodiment, cannot limit claimed model with this
It encloses, the modification and replacement for any substance that those skilled in the art is done on the basis of the present invention belong to the present invention and want
Seek the range of protection.
Working principle: raw material sources of the invention are extensive, and preparation process is simple.Salicylic acid and niacinamide can help striae of pregnancy
Skin quickly updates surface layer cuticula, and the striae of pregnancy of white is made to seem less obvious.Hydroxyproline, gold safron are extracted
Object, Gotu Kola P.E three can act synergistically on skin corium, promote the synthesis of collagen and elastin laminin, function and effect energy
It matches in excellence or beauty and converts growth factor TGF-β.The composition is started with from skin surface cuticula and skin corium, is worked along both lines, and is counted after tested
According to showing that the composition educated Ms and have the effect of good desalination striae of pregnancy for non-lactation period, without toxic side effect, expire
The foot use demand of people.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding
And modification, the scope of the present invention is defined by the appended.
Claims (11)
1. a kind of desalination striae of pregnancy composition, it is characterised in that: the raw material including following parts by weight: emulsifier 2-4%, grease 5-
40%, thickener 0.05-3%, moisturizer 0.05-20%, antioxidant 0.05-1%, preservative 0.2-1%, efficacy activity object
0.2-10%, deionized water surplus.
2. desalination striae of pregnancy composition according to claim 1, it is characterised in that: the emulsifier include A165, M68,
One or more of emulsifier of M82, M202.
3. desalination striae of pregnancy composition according to claim 1, it is characterised in that: the grease include olive oil, octanoic acid/
One or more of Triglyceride DDD, cocoa seed rouge, dimethyl silicone polymer, white pond flower seed oil, shea butter.
4. desalination striae of pregnancy composition according to claim 1, it is characterised in that: the thickener includes xanthan gum, whale
One or more of wax stearyl alcohol, carbomer.
5. desalination striae of pregnancy composition according to claim 1, it is characterised in that: the moisturizer includes glycerol, the third two
Alcohol, butanediol, dipropylene glycol, glycerin polyether -26, Sodium Hyaluronate, trehalose, allantoin, polyglutamic acid, one in glycine betaine
Kind is two or more.
6. desalination striae of pregnancy composition according to claim 1, it is characterised in that: the antioxidant includes tocopherol.
7. desalination striae of pregnancy composition according to claim 1, it is characterised in that: the preservative includes 1,2- penta 2
One or more of alcohol, parahydroxyacet-ophenone, 1,2- hexylene glycol, decoyl hydroximic acid, Phenoxyethanol, glycerol caprylate.
8. desalination striae of pregnancy composition according to claim 1, it is characterised in that: the efficacy activity object includes gold kind
Safflower extract, Gotu Kola P.E, salicylic acid, hydroxyproline, niacinamide.
9. desalinating the preparation method of striae of pregnancy composition, which is characterized in that specific step is as follows:
Step 1: the emulsifier, grease, antioxidant are mixed and are warming up to 75-80 DEG C, obtains mixture one, it is spare；
Step 2: the moisturizer, thickener are mixed and are warming up to 75-80 DEG C, obtains mixture two, it is spare；
Step 3: mixture one being added in mixture two, and homogeneous 5 minutes, then low speed vacuum stirs 15 minutes, stirring
After be cooled to 40 DEG C, obtain mixture three；
Step 4: remaining raw material being added in mixture three and is stirred evenly and desalinates striae of pregnancy composition to get to final.
10. the preparation method of desalination striae of pregnancy composition according to claim 9, it is characterised in that: in the step 3
The speed of matter be 2500-3000rpm, low speed vacuum stirring revolving speed be 50-70rpm, vacuum degree be -0.06Mpa~-
0.08Mpa。
11. the preparation method of desalination striae of pregnancy composition according to claim 9, it is characterised in that: dropped in the step 3
Warm speed is 1 DEG C/min.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112451460A (en) * | 2020-12-31 | 2021-03-09 | 广州市医康生物科技有限公司 | Extraction method of crocus sativus extract and stretch mark removing cream containing extract |
| CN112545949A (en) * | 2021-01-15 | 2021-03-26 | 东晟源研究院(广州)有限公司 | Composition with effects of resisting oxidation and homogenizing skin color and preparation method thereof |
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| CN103655355A (en) * | 2013-12-19 | 2014-03-26 | 栾晓健 | Lotion capable of removing stretch marks |
| CN106963677A (en) * | 2017-03-24 | 2017-07-21 | 宁波希诺亚海洋生物科技有限公司 | One kind is except striae of pregnancy frost |
| CN109125173A (en) * | 2018-09-19 | 2019-01-04 | 李燕 | A kind of face cream and preparation method thereof removing striae of pregnancy |
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| CN101152138A (en) * | 2007-09-29 | 2008-04-02 | 天津盛世恒安科技发展有限公司 | Face-painting product having function of dispelling stria gravidarum and method for preparing the same |
| CN103655355A (en) * | 2013-12-19 | 2014-03-26 | 栾晓健 | Lotion capable of removing stretch marks |
| CN106963677A (en) * | 2017-03-24 | 2017-07-21 | 宁波希诺亚海洋生物科技有限公司 | One kind is except striae of pregnancy frost |
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| CN112451460A (en) * | 2020-12-31 | 2021-03-09 | 广州市医康生物科技有限公司 | Extraction method of crocus sativus extract and stretch mark removing cream containing extract |
| CN112545949A (en) * | 2021-01-15 | 2021-03-26 | 东晟源研究院(广州)有限公司 | Composition with effects of resisting oxidation and homogenizing skin color and preparation method thereof |
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Application publication date: 20191015 |