CL2013003160A1 - Compuestos derivados de 4h-cromen-4-ona moduladores de la proteina cinasa pi3k; compuestos intermediarios; composicion farmaceutica que los comprende; y utiles en el tratamiento del cancer, agentes antinflamatorios, inmunosupresores, esteroides, analgesicos, leucemia, entre otros. - Google Patents
Compuestos derivados de 4h-cromen-4-ona moduladores de la proteina cinasa pi3k; compuestos intermediarios; composicion farmaceutica que los comprende; y utiles en el tratamiento del cancer, agentes antinflamatorios, inmunosupresores, esteroides, analgesicos, leucemia, entre otros.Info
- Publication number
- CL2013003160A1 CL2013003160A1 CL2013003160A CL2013003160A CL2013003160A1 CL 2013003160 A1 CL2013003160 A1 CL 2013003160A1 CL 2013003160 A CL2013003160 A CL 2013003160A CL 2013003160 A CL2013003160 A CL 2013003160A CL 2013003160 A1 CL2013003160 A1 CL 2013003160A1
- Authority
- CL
- Chile
- Prior art keywords
- compounds
- chromen
- immunosuppressants
- analgesics
- steroids
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 229940035676 analgesics Drugs 0.000 title abstract 2
- 239000000730 antalgic agent Substances 0.000 title abstract 2
- 239000002260 anti-inflammatory agent Substances 0.000 title abstract 2
- 229940121363 anti-inflammatory agent Drugs 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title abstract 2
- OTAFHZMPRISVEM-UHFFFAOYSA-N chromone Chemical compound C1=CC=C2C(=O)C=COC2=C1 OTAFHZMPRISVEM-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003444 immunosuppressant agent Drugs 0.000 title abstract 2
- 239000003018 immunosuppressive agent Substances 0.000 title abstract 2
- 208000032839 leukemia Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000003431 steroids Chemical class 0.000 title abstract 2
- 102000001253 Protein Kinase Human genes 0.000 title 1
- 108060006633 protein kinase Proteins 0.000 title 1
- 102000038030 PI3Ks Human genes 0.000 abstract 1
- 108091007960 PI3Ks Proteins 0.000 abstract 1
Classifications
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- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
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Abstract
La presente invención proporciona compuestos derivados de 4H-cromen-4-ona moduladores de la proteína cinasa PI3K, de formula I; compuestos intermediarios; composición farmacéutica que los comprende; y útiles en el tratamiento del cáncer, agentes antinflamatorios, inmunosupresores, esteroides, analgésicos, leucemia, entre otros.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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IN1542CH2011 | 2011-05-04 | ||
IN81CH2012 | 2012-01-09 |
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CL2013003160A1 true CL2013003160A1 (es) | 2014-09-26 |
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CL2013003160A CL2013003160A1 (es) | 2011-05-04 | 2013-11-04 | Compuestos derivados de 4h-cromen-4-ona moduladores de la proteina cinasa pi3k; compuestos intermediarios; composicion farmaceutica que los comprende; y utiles en el tratamiento del cancer, agentes antinflamatorios, inmunosupresores, esteroides, analgesicos, leucemia, entre otros. |
Country Status (29)
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US (5) | US9775841B2 (es) |
EP (1) | EP2705029B1 (es) |
JP (2) | JP6118314B2 (es) |
KR (1) | KR101992311B1 (es) |
CN (2) | CN107337659A (es) |
AP (1) | AP4075A (es) |
AU (1) | AU2012250576B2 (es) |
BR (1) | BR112013027774B1 (es) |
CA (1) | CA2833935C (es) |
CL (1) | CL2013003160A1 (es) |
CO (1) | CO6852069A2 (es) |
CY (1) | CY1121170T1 (es) |
DK (1) | DK2705029T3 (es) |
EA (1) | EA024842B9 (es) |
ES (1) | ES2710874T3 (es) |
HR (1) | HRP20190128T1 (es) |
HU (1) | HUE042322T2 (es) |
LT (1) | LT2705029T (es) |
MX (1) | MX365160B (es) |
MY (1) | MY168757A (es) |
PH (1) | PH12013502240B1 (es) |
PL (1) | PL2705029T4 (es) |
PT (1) | PT2705029T (es) |
RS (1) | RS58326B1 (es) |
SG (1) | SG194718A1 (es) |
SI (1) | SI2705029T1 (es) |
SM (1) | SMT201900056T1 (es) |
WO (1) | WO2012151525A1 (es) |
ZA (1) | ZA201307964B (es) |
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