|
CH593992A5
(fr)
*
|
1972-12-23 |
1977-12-30 |
Roehm Gmbh |
|
|
GB1550819A
(en)
*
|
1975-06-04 |
1979-08-22 |
Nat Res Dev |
Polymeric support for biogically active materials
|
|
JPS5272284A
(en)
*
|
1975-12-12 |
1977-06-16 |
Dainippon Pharmaceutical Co |
Enzymeeimmunoassay reagent
|
|
US4108804A
(en)
*
|
1975-12-23 |
1978-08-22 |
Toru Seita |
Process for preparation of chromatography solid supports comprising a nucleic acid base-epoxy group containing porous gel
|
|
US4046723A
(en)
*
|
1976-04-22 |
1977-09-06 |
The Dow Chemical Company |
Azide bonding of a protein to a latex
|
|
US4206261A
(en)
*
|
1976-06-09 |
1980-06-03 |
Schenectady Chemicals, Inc. |
Water-soluble polyester imide resin wire coating process
|
|
US4179423A
(en)
*
|
1976-06-09 |
1979-12-18 |
Schenectady Chemicals, Inc. |
Water-soluble polyester imide resins
|
|
US4045384A
(en)
*
|
1976-07-23 |
1977-08-30 |
The Dow Chemical Company |
Method for forming an amide bond between a latex and protein
|
|
DE2708018A1
(de)
*
|
1977-02-24 |
1978-09-07 |
Boehringer Mannheim Gmbh |
An polyamid fixiertes biologisch aktives protein und verfahren zu seiner herstellung
|
|
DE2862449D1
(en)
*
|
1977-08-22 |
1984-11-22 |
Nat Res Dev |
Macromolecular covalent conjugates, methods for preparing and pharmaceutical compositions containing them
|
|
US4206286A
(en)
*
|
1977-11-14 |
1980-06-03 |
Technicon Instruments Corporation |
Immobilization of proteins on inorganic supports
|
|
US4338398A
(en)
*
|
1979-03-20 |
1982-07-06 |
Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo |
Immobilization of starch degrading enzymes
|
|
US4415665A
(en)
*
|
1980-12-12 |
1983-11-15 |
Pharmacia Fine Chemicals Ab |
Method of covalently binding biologically active organic substances to polymeric substances
|
|
DE3126551C2
(de)
*
|
1981-07-04 |
1983-12-15 |
Rolf Dr. 8700 Würzburg Siegel |
Herstellungsverfahren für Materialien zur Immobilisierung von Proteinen und Kohlenhydratgruppen
|
|
US4506019A
(en)
*
|
1982-09-24 |
1985-03-19 |
Leeco Diagnostics, Inc. |
Activated polymer container means and assay method employing the same
|
|
US4596777A
(en)
*
|
1983-08-10 |
1986-06-24 |
E. R. Squibb & Sons, Inc. |
Process for preparing (3S)-3-[[[2-(protected or unprotected amino)-4-thiazolyl]acetyl]amino]-2-oxo-1-azetidinesulfonic acid and 4-substituted derivatives thereof
|
|
DE142810T1
(de)
*
|
1983-11-10 |
1985-12-19 |
Genetic Systems Corp., Seattle, Wash. |
Integralpolypeptide enthaltende polymerisierbare verbindungen und deren anwendungen in immuntesten mit durch polymerisation induzierter trennung.
|
|
US4609707A
(en)
*
|
1983-11-10 |
1986-09-02 |
Genetic Systems Corporation |
Synthesis of polymers containing integral antibodies
|
|
US4843010A
(en)
*
|
1983-11-10 |
1989-06-27 |
Genetic Systems Corporation |
Polymerization-induced separation immunoassays
|
|
US4752638A
(en)
*
|
1983-11-10 |
1988-06-21 |
Genetic Systems Corporation |
Synthesis and use of polymers containing integral binding-pair members
|
|
US4511478A
(en)
*
|
1983-11-10 |
1985-04-16 |
Genetic Systems Corporation |
Polymerizable compounds and methods for preparing synthetic polymers that integrally contain polypeptides
|
|
US4711840A
(en)
*
|
1984-01-27 |
1987-12-08 |
Genetic Systems Corporation |
Polymerization-induced separation immunoassays
|
|
JPH0820447B2
(ja)
*
|
1984-01-27 |
1996-03-04 |
ジェネティック システムズ コーポレーション |
液体混合物から物質を分離する方法及び免疫評価法
|
|
US4695624A
(en)
*
|
1984-05-10 |
1987-09-22 |
Merck & Co., Inc. |
Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency
|
|
US4749647A
(en)
*
|
1984-06-22 |
1988-06-07 |
Genetic Systems Corporation |
Polymerization-induced separation assay using recognition pairs
|
|
EP0257758B1
(fr)
*
|
1986-08-07 |
1993-03-10 |
Minnesota Mining And Manufacturing Company |
Emulsions fluorochimiques biologiquement actives, stables
|
|
US4808530A
(en)
*
|
1986-09-05 |
1989-02-28 |
The Ohio State University |
Protein immobilization by adsorption of a hydrophobic amidine protein derivative to a hydrophobic surface
|
|
US4885250A
(en)
*
|
1987-03-02 |
1989-12-05 |
E. I. Du Pont De Nemours And Company |
Enzyme immobilization and bioaffinity separations with perfluorocarbon polymer-based supports
|
|
US5063109A
(en)
*
|
1988-10-11 |
1991-11-05 |
Abbott Laboratories |
Covalent attachment of antibodies and antigens to solid phases using extended length heterobifunctional coupling agents
|
|
US5116964A
(en)
|
1989-02-23 |
1992-05-26 |
Genentech, Inc. |
Hybrid immunoglobulins
|
|
DE69116034T2
(de)
*
|
1990-08-15 |
1996-06-20 |
Abbott Lab |
Immunotestreagenzien und Verfahren zur Bestimmung von Cyclosporin
|
|
US5612034A
(en)
*
|
1990-10-03 |
1997-03-18 |
Redcell, Inc. |
Super-globuling for in vivo extended lifetimes
|
|
US5482996A
(en)
*
|
1993-12-08 |
1996-01-09 |
University Of Pittsburgh |
Protein-containing polymers and a method of synthesis of protein-containing polymers in organic solvents
|
|
US6057287A
(en)
*
|
1994-01-11 |
2000-05-02 |
Dyax Corp. |
Kallikrein-binding "Kunitz domain" proteins and analogues thereof
|
|
PT739355E
(pt)
|
1994-01-11 |
2005-01-31 |
Dyax Corp |
Proteinas de 'dominio de kunitz' inibidoras de calicreina e seus analogos
|
|
US6045797A
(en)
*
|
1994-03-14 |
2000-04-04 |
New York University Medical Center |
Treatment or diagnosis of diseases or conditions associated with a BLM domain
|
|
US5877016A
(en)
|
1994-03-18 |
1999-03-02 |
Genentech, Inc. |
Human trk receptors and neurotrophic factor inhibitors
|
|
US5708142A
(en)
|
1994-05-27 |
1998-01-13 |
Genentech, Inc. |
Tumor necrosis factor receptor-associated factors
|
|
US5736624A
(en)
*
|
1994-12-02 |
1998-04-07 |
Abbott Laboratories |
Phosphatase activated crosslinking, conjugating and reducing agents; methods of using such agents; and reagents comprising phosphatase activated crosslinking and conjugating agents
|
|
US5837815A
(en)
*
|
1994-12-15 |
1998-11-17 |
Sugen, Inc. |
PYK2 related polypeptide products
|
|
US5837524A
(en)
*
|
1994-12-15 |
1998-11-17 |
Sugen, Inc. |
PYK2 related polynucleotide products
|
|
US5807989A
(en)
*
|
1994-12-23 |
1998-09-15 |
New York University |
Methods for treatment or diagnosis of diseases or disorders associated with an APB domain
|
|
US6300482B1
(en)
|
1995-01-03 |
2001-10-09 |
Max-Flanck-Gesellschaft Zuer For{Overscore (D)}Erung Der |
MDKI, a novel receptor tyrosine kinase
|
|
US6565842B1
(en)
*
|
1995-06-07 |
2003-05-20 |
American Bioscience, Inc. |
Crosslinkable polypeptide compositions
|
|
US7005505B1
(en)
|
1995-08-25 |
2006-02-28 |
Genentech, Inc. |
Variants of vascular endothelial cell growth factor
|
|
US6020473A
(en)
*
|
1995-08-25 |
2000-02-01 |
Genentech, Inc. |
Nucleic acids encoding variants of vascular endothelial cell growth factor
|
|
AU725399B2
(en)
|
1995-09-15 |
2000-10-12 |
Baylor College Of Medicine |
Steroid receptor coactivator compositions and methods of use
|
|
US6046048A
(en)
*
|
1996-01-09 |
2000-04-04 |
Genetech, Inc. |
Apo-2 ligand
|
|
US6998116B1
(en)
*
|
1996-01-09 |
2006-02-14 |
Genentech, Inc. |
Apo-2 ligand
|
|
US20050089958A1
(en)
*
|
1996-01-09 |
2005-04-28 |
Genentech, Inc. |
Apo-2 ligand
|
|
US6030945A
(en)
*
|
1996-01-09 |
2000-02-29 |
Genentech, Inc. |
Apo-2 ligand
|
|
JP2000507829A
(ja)
*
|
1996-04-01 |
2000-06-27 |
ジェネンテック インコーポレーテッド |
Apo―2liおよびapo―3アポトーシスポリペプチド
|
|
US20020165157A1
(en)
*
|
1996-04-01 |
2002-11-07 |
Genentech, Inc. |
Apo-2LI and Apo-3 polypeptides
|
|
US6100071A
(en)
|
1996-05-07 |
2000-08-08 |
Genentech, Inc. |
Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production
|
|
US6159462A
(en)
*
|
1996-08-16 |
2000-12-12 |
Genentech, Inc. |
Uses of Wnt polypeptides
|
|
US5851984A
(en)
*
|
1996-08-16 |
1998-12-22 |
Genentech, Inc. |
Method of enhancing proliferation or differentiation of hematopoietic stem cells using Wnt polypeptides
|
|
US6462176B1
(en)
*
|
1996-09-23 |
2002-10-08 |
Genentech, Inc. |
Apo-3 polypeptide
|
|
WO1998033924A1
(fr)
|
1997-01-31 |
1998-08-06 |
Genentech, Inc. |
O-fucosyltransferase
|
|
US20040241645A1
(en)
*
|
1997-01-31 |
2004-12-02 |
Genentech, Inc. |
O-fucosyltransferase
|
|
US20020102706A1
(en)
*
|
1997-06-18 |
2002-08-01 |
Genentech, Inc. |
Apo-2DcR
|
|
DE69838249T3
(de)
|
1997-05-15 |
2012-01-19 |
Genentech, Inc. |
Anti-apo-2 antikörper
|
|
US6342369B1
(en)
*
|
1997-05-15 |
2002-01-29 |
Genentech, Inc. |
Apo-2-receptor
|
|
US20100152426A1
(en)
*
|
1997-05-15 |
2010-06-17 |
Ashkenazi Avi J |
Apo-2 receptor fusion proteins
|
|
JP2001523977A
(ja)
|
1997-06-05 |
2001-11-27 |
ザ ユニバーシティ オブ テキサス システム ボード オブ リージェンツ |
Apaf−1、ced−4ヒト相同体、カスパーゼ−3の活性化因子
|
|
AU740227B2
(en)
*
|
1997-06-18 |
2001-11-01 |
Genentech Inc. |
Apo-2DcR
|
|
US6506550B1
(en)
|
1997-07-11 |
2003-01-14 |
Brandeis University |
Method of including apoptosis by reducing the level of thiamin
|
|
US20030175856A1
(en)
*
|
1997-08-26 |
2003-09-18 |
Genetech, Inc. |
Rtd receptor
|
|
PT1009817E
(pt)
*
|
1997-08-26 |
2009-12-30 |
Genentech Inc |
Receptor de rtd
|
|
US20060141036A1
(en)
*
|
1997-12-12 |
2006-06-29 |
Andrx Labs Llc |
HMG-CoA reductase inhibitor extended release formulation
|
|
ES2316182T3
(es)
|
1998-01-15 |
2009-04-01 |
Genentech, Inc. |
Ligando apo-2.
|
|
JP2002517223A
(ja)
*
|
1998-06-12 |
2002-06-18 |
ジェネンテック・インコーポレーテッド |
モノクローナル抗体、交叉反応性抗体およびそれを生成する方法
|
|
US6984719B1
(en)
|
1998-09-17 |
2006-01-10 |
Hospital Sainte-Justine |
Peptide antagonists of prostaglandin F2α receptor
|
|
US6368793B1
(en)
*
|
1998-10-14 |
2002-04-09 |
Microgenomics, Inc. |
Metabolic selection methods
|
|
US6660843B1
(en)
*
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
|
DK2319928T3
(da)
*
|
1998-10-23 |
2013-06-24 |
Kirin Amgen Inc |
Dimere trombopoietiske peptidomimetika, der binder til MPL-receptor og har trombopoietisk aktivitet
|
|
US6982153B1
(en)
|
1998-12-03 |
2006-01-03 |
Targanta Therapeutics, Inc. |
DNA sequences from staphylococcus aureus bacteriophage 77 that encode anti-microbial polypeptides
|
|
US6861442B1
(en)
*
|
1998-12-30 |
2005-03-01 |
Sugen, Inc. |
PYK2 and inflammation
|
|
CA2376717A1
(fr)
*
|
1999-06-16 |
2000-12-21 |
Icos Corporation |
Materiaux poly(adp-ribose) polymerase 2 humains et procedes
|
|
US20040235749A1
(en)
*
|
1999-09-15 |
2004-11-25 |
Sylvain Chemtob |
G-protein coupled receptor antagonists
|
|
US20030138771A1
(en)
*
|
1999-09-30 |
2003-07-24 |
Jerry Pelletier |
DNA sequences from S. pneumoniae bacteriophage DP1 that encode anti-microbal polypeptides
|
|
US6808902B1
(en)
|
1999-11-12 |
2004-10-26 |
Amgen Inc. |
Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
|
|
KR100749982B1
(ko)
|
1999-11-16 |
2007-08-16 |
제넨테크, 인크. |
혈관 내피 성장 인자용 elisa
|
|
DK1290013T3
(da)
|
2000-04-21 |
2006-06-26 |
Amgen Inc |
Apo-A1/All-peptidderivater
|
|
US6667300B2
(en)
|
2000-04-25 |
2003-12-23 |
Icos Corporation |
Inhibitors of human phosphatidylinositol 3-kinase delta
|
|
US6677136B2
(en)
|
2000-05-03 |
2004-01-13 |
Amgen Inc. |
Glucagon antagonists
|
|
MXPA03001142A
(es)
*
|
2000-08-11 |
2004-08-02 |
Favrille Inc |
Metodo y composicion para alterar una patologia mediada por celulas t.
|
|
US6911204B2
(en)
*
|
2000-08-11 |
2005-06-28 |
Favrille, Inc. |
Method and composition for altering a B cell mediated pathology
|
|
CN1970078A
(zh)
|
2001-05-11 |
2007-05-30 |
安姆根有限公司 |
与tall-1结合的肽和相关分子
|
|
ES2466024T3
(es)
|
2001-10-10 |
2014-06-09 |
Ratiopharm Gmbh |
Remodelación y glicoconjugación de factor de crecimiento de fibroblastos (FGF)
|
|
US7138370B2
(en)
|
2001-10-11 |
2006-11-21 |
Amgen Inc. |
Specific binding agents of human angiopoietin-2
|
|
US7332474B2
(en)
*
|
2001-10-11 |
2008-02-19 |
Amgen Inc. |
Peptides and related compounds having thrombopoietic activity
|
|
US20040054082A1
(en)
*
|
2001-12-03 |
2004-03-18 |
Bank David H |
Toughened polymer blends with improved surface properties
|
|
US20070122406A1
(en)
|
2005-07-08 |
2007-05-31 |
Xencor, Inc. |
Optimized proteins that target Ep-CAM
|
|
US20100311954A1
(en)
*
|
2002-03-01 |
2010-12-09 |
Xencor, Inc. |
Optimized Proteins that Target Ep-CAM
|
|
ES2348230T3
(es)
*
|
2002-06-07 |
2010-12-01 |
Dyax Corp. |
Prevención y reducción de la isquemia.
|
|
US7153829B2
(en)
*
|
2002-06-07 |
2006-12-26 |
Dyax Corp. |
Kallikrein-inhibitor therapies
|
|
US7521530B2
(en)
*
|
2002-06-11 |
2009-04-21 |
Universite De Montreal |
Peptides and peptidomimetics useful for inhibiting the activity of prostaglandin F2α receptor
|
|
PT2386310T
(pt)
*
|
2002-08-28 |
2019-02-05 |
Dyax Corp |
Métodos para preservar órgãos e tecidos
|
|
US6919426B2
(en)
|
2002-09-19 |
2005-07-19 |
Amgen Inc. |
Peptides and related molecules that modulate nerve growth factor activity
|
|
US20070026485A1
(en)
|
2003-04-09 |
2007-02-01 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
|
US20050043239A1
(en)
*
|
2003-08-14 |
2005-02-24 |
Jason Douangpanya |
Methods of inhibiting immune responses stimulated by an endogenous factor
|
|
US20050054614A1
(en)
*
|
2003-08-14 |
2005-03-10 |
Diacovo Thomas G. |
Methods of inhibiting leukocyte accumulation
|
|
US20060134105A1
(en)
*
|
2004-10-21 |
2006-06-22 |
Xencor, Inc. |
IgG immunoglobulin variants with optimized effector function
|
|
US8883147B2
(en)
|
2004-10-21 |
2014-11-11 |
Xencor, Inc. |
Immunoglobulins insertions, deletions, and substitutions
|
|
US8399618B2
(en)
|
2004-10-21 |
2013-03-19 |
Xencor, Inc. |
Immunoglobulin insertions, deletions, and substitutions
|
|
WO2005079779A1
(fr)
*
|
2003-10-22 |
2005-09-01 |
Merz Pharma Gmbh & Co. Kgaa |
Utilisation de derives de 1-aminocyclohexane pour modifier le depot de peptides a$g(b) fibrillogenes dans des amyloidopathies
|
|
ATE507240T1
(de)
|
2004-03-05 |
2011-05-15 |
Vegenics Pty Ltd |
Materialien und verfahren für wachstumsfaktorbindende konstrukte
|
|
AU2005241431A1
(en)
*
|
2004-04-16 |
2005-11-17 |
Genentech, Inc. |
Assay for antibodies
|
|
RS55551B1
(sr)
|
2004-05-13 |
2017-05-31 |
Icos Corp |
Hinazolinoni kao inhibitori humane fosfatidilinozitol 3-kinaze delta
|
|
WO2005114218A2
(fr)
*
|
2004-05-15 |
2005-12-01 |
Genentech, Inc. |
Système de criblage croisé et méthodes pour détecter une molécule ayant une affinité de liaison pour une molécule cible
|
|
JP2008500338A
(ja)
*
|
2004-05-25 |
2008-01-10 |
イコス・コーポレイション |
造血細胞の異常増殖を治療及び/又は予防する方法
|
|
EP1773400A2
(fr)
*
|
2004-07-08 |
2007-04-18 |
Amgen Inc. |
Peptides therapeutiques
|
|
CN101103045B
(zh)
*
|
2004-09-24 |
2015-11-25 |
安姆根有限公司 |
修饰的Fc分子
|
|
US7235530B2
(en)
*
|
2004-09-27 |
2007-06-26 |
Dyax Corporation |
Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
|
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
AU2005304624B2
(en)
|
2004-11-12 |
2010-10-07 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
EP1833970A2
(fr)
|
2004-12-22 |
2007-09-19 |
Genentech, Inc. |
Procedes pour la production d'une pluralite de proteines transmembranaires solubles
|
|
AU2006214190A1
(en)
*
|
2005-02-17 |
2006-08-24 |
Icos Corporation |
Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
|
|
US8008453B2
(en)
|
2005-08-12 |
2011-08-30 |
Amgen Inc. |
Modified Fc molecules
|
|
US20070161089A1
(en)
*
|
2005-11-08 |
2007-07-12 |
Genentech, Inc. |
Method of Producing Pan-Specific Antibodies
|
|
AR056806A1
(es)
|
2005-11-14 |
2007-10-24 |
Amgen Inc |
Moleculas quimericas de anticuerpo rankl- pth/ pthrp
|
|
US7276480B1
(en)
|
2005-12-30 |
2007-10-02 |
Dyax Corp. |
Prevention and reduction of blood loss
|
|
US9012605B2
(en)
|
2006-01-23 |
2015-04-21 |
Amgen Inc. |
Crystalline polypeptides
|
|
JP2009529542A
(ja)
*
|
2006-03-10 |
2009-08-20 |
ダイアックス コーポレーション |
エカランチドに関する配合物
|
|
JO3324B1
(ar)
|
2006-04-21 |
2019-03-13 |
Amgen Inc |
مركبات علاجية مجففة بالتبريد تتعلق بالعصارة الهضمية
|
|
US7981425B2
(en)
|
2006-06-19 |
2011-07-19 |
Amgen Inc. |
Thrombopoietic compounds
|
|
AU2007265475B2
(en)
|
2006-06-26 |
2010-08-19 |
Amgen Inc. |
Methods for treating atherosclerosis
|
|
ATE531727T1
(de)
*
|
2006-09-18 |
2011-11-15 |
Compugen Ltd |
Bioaktive peptide und verfahren zu ihrer verwendung
|
|
US7767206B2
(en)
|
2006-10-02 |
2010-08-03 |
Amgen Inc. |
Neutralizing determinants of IL-17 Receptor A and antibodies that bind thereto
|
|
AR063125A1
(es)
|
2006-10-04 |
2008-12-30 |
Genentech Inc |
Ensayo elisa para la deteccion de vegf
|
|
WO2008051383A2
(fr)
*
|
2006-10-19 |
2008-05-02 |
Amgen Inc. |
Utilisation de co-solvants d'alcool pour améliorer les rendements de réaction de pegylation
|
|
US7820623B2
(en)
|
2006-10-25 |
2010-10-26 |
Amgen Inc. |
Conjugated toxin peptide therapeutic agents
|
|
WO2008079322A1
(fr)
*
|
2006-12-22 |
2008-07-03 |
Beckman Coulter, Inc. |
Procédés, coffrets et matériels pour diagnostiquer des états de maladie par la mesure d'isoformes ou de proformes de la myéloperoxydase
|
|
AU2008262490B2
(en)
|
2007-05-22 |
2011-11-17 |
Amgen Inc. |
Compositions and methods for producing bioactive fusion proteins
|
|
AU2008273813B2
(en)
|
2007-07-12 |
2013-06-13 |
Compugen Ltd. |
Bioactive peptides and method of using same
|
|
DK2181190T3
(da)
|
2007-07-26 |
2014-03-31 |
Amgen Inc |
Modificerede lecithin-kolesterol-acyltransferase-enzymer
|
|
US8715684B2
(en)
|
2007-08-28 |
2014-05-06 |
Ramot At Tel Aviv University Ltd. |
Peptides inducing a CD4i conformation in HIV gp120 while retaining vacant CD4 binding site
|
|
PL2235059T3
(pl)
|
2007-12-26 |
2015-08-31 |
Xencor Inc |
Warianty FC o zmodyfikowanym wiązaniu do FCRN
|
|
US8129341B2
(en)
*
|
2008-08-25 |
2012-03-06 |
New York University |
Methods for treating diabetic wounds
|
|
CN102271683B
(zh)
|
2008-11-13 |
2014-07-09 |
吉里德卡利斯托加公司 |
恶性血液病的治疗
|
|
US9492449B2
(en)
|
2008-11-13 |
2016-11-15 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
|
US8637454B2
(en)
*
|
2009-01-06 |
2014-01-28 |
Dyax Corp. |
Treatment of mucositis with kallikrein inhibitors
|
|
CA2756347A1
(fr)
|
2009-03-24 |
2010-09-30 |
Gilead Calistoga Llc |
Atropisomeres de derives de 2-purinyl-3-tolyl-quinazolinone et procedes d'utilisation
|
|
CA2759724A1
(fr)
*
|
2009-04-20 |
2010-10-28 |
Calistoga Pharmaceuticals, Inc. |
Procedes de traitement de tumeurs solides
|
|
CA2768843A1
(fr)
|
2009-07-21 |
2011-01-27 |
Gilead Calistoga Llc |
Traitement de troubles du foie par des inhibiteurs de pi3k
|
|
TW201117824A
(en)
|
2009-10-12 |
2011-06-01 |
Amgen Inc |
Use of IL-17 receptor a antigen binding proteins
|
|
WO2011049625A1
(fr)
|
2009-10-20 |
2011-04-28 |
Mansour Samadpour |
Procédé de criblage d'aflatoxine dans des produits
|
|
MY182750A
(en)
*
|
2009-10-26 |
2021-02-05 |
Genentech Inc |
Assays for detecting antibodies specific to therapeutic anti-ige antibodies and their use in anaphylaxis
|
|
HUE035059T2
(hu)
|
2009-11-05 |
2018-05-02 |
Rhizen Pharmaceuticals S A |
Új benzopirán-kinát modulátorok
|
|
RS62853B1
(sr)
|
2010-01-06 |
2022-02-28 |
Takeda Pharmaceuticals Co |
Proteini koji vezuju kalikrein plazme
|
|
WO2011097527A2
(fr)
|
2010-02-04 |
2011-08-11 |
Xencor, Inc. |
Immunoprotection de fractions thérapeutiques avec des régions fc améliorées
|
|
US20110189178A1
(en)
*
|
2010-02-04 |
2011-08-04 |
Xencor, Inc. |
Immunoprotection of Therapeutic Moieties Using Enhanced Fc Regions
|
|
DK2547359T3
(en)
|
2010-03-15 |
2016-06-06 |
The Board Of Trustees Of The Univ Of Illionis |
Inhibitors of beta integrin G-protein alpha subunit-BINDING INTERACTIONS
|
|
KR101871436B1
(ko)
|
2010-05-17 |
2018-06-27 |
인코젠 쎄라퓨틱스 프라이빗 리미티드 |
단백질 키나제의 조절제로서의 신규한 3,5-디치환-3h-이미다조[4,5-b]피리딘 및 3,5- 디치환 -3h-[1,2,3]트리아졸로[4,5-b] 피리딘 화합물
|
|
US9254310B2
(en)
|
2010-06-17 |
2016-02-09 |
New York University |
Therapeutic and cosmetic uses and applications of calreticulin
|
|
WO2012030738A2
(fr)
|
2010-08-30 |
2012-03-08 |
Beckman Coulter, Inc. |
Profils complexes d'activation de phosphoprotéines
|
|
EP3219731A1
(fr)
|
2010-10-01 |
2017-09-20 |
Oxford BioTherapeutics Ltd |
Anticorps anti-ror1
|
|
US9029502B2
(en)
|
2010-12-20 |
2015-05-12 |
The Regents Of The University Of Michigan |
Inhibitors of the epidermal growth factor receptor-heat shock protein 90 binding interaction
|
|
JOP20210044A1
(ar)
|
2010-12-30 |
2017-06-16 |
Takeda Pharmaceuticals Co |
الأجسام المضادة لـ cd38
|
|
CN103635489B
(zh)
|
2011-01-06 |
2016-04-13 |
戴埃克斯有限公司 |
血浆前激肽释放酶结合蛋白
|
|
AU2012228990B2
(en)
|
2011-03-16 |
2017-04-06 |
Amgen Inc. |
Potent and selective inhibitors of Nav1.3 and Nav1.7
|
|
EP2702076A1
(fr)
|
2011-04-29 |
2014-03-05 |
Bristol-Myers Squibb Company |
Schémas posologiques à doses progressivement croissantes d'anticorps anti-ip-10
|
|
ES2710874T3
(es)
|
2011-05-04 |
2019-04-29 |
Rhizen Pharmaceuticals S A |
Compuestos novedosos como moduladores de proteína cinasas
|
|
WO2013016220A1
(fr)
|
2011-07-22 |
2013-01-31 |
Amgen Inc. |
Récepteur a de il-il-17 requis pour biologie il-17c
|
|
MY173865A
(en)
|
2011-09-22 |
2020-02-25 |
Amgen Inc |
Cd27l antigen binding proteins
|
|
US12466897B2
(en)
|
2011-10-10 |
2025-11-11 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對bcma之e3以及cd3的結合分子
|
|
AR090253A1
(es)
|
2012-03-05 |
2014-10-29 |
Gilead Calistoga Llc |
Formas polimorficas de (s)-2-(1-(9h-purin-6-ilamino)propil)-5-fluor-3-fenilquinazolin-4(3h)-ona
|
|
US20150079100A1
(en)
|
2012-03-23 |
2015-03-19 |
Bristol-Myers Squibb Company |
Methods of treatments using ctla-4 antibodies
|
|
EP2831119A1
(fr)
*
|
2012-03-28 |
2015-02-04 |
F. Hoffmann-La Roche AG |
Anticorps idiotypiques anti-hcmv et leurs utilisations
|
|
CN104321322A
(zh)
|
2012-03-30 |
2015-01-28 |
理森制药股份公司 |
作为c-met蛋白激酶调节剂的新型3,5-二取代-3h-咪唑并[4,5-b]吡啶和3,5-二取代-3h-[1,2,3]三唑并[4,5-b]吡啶化合物
|
|
WO2013155346A1
(fr)
|
2012-04-11 |
2013-10-17 |
The Regents Of The University Of California |
Outils diagnostiques pour la réponse au traitement par 6-thiopurines
|
|
UY34813A
(es)
|
2012-05-18 |
2013-11-29 |
Amgen Inc |
Proteínas de unión a antígeno dirigidas contra el receptor st2
|
|
TW201425336A
(zh)
|
2012-12-07 |
2014-07-01 |
Amgen Inc |
Bcma抗原結合蛋白質
|
|
WO2014099984A1
(fr)
|
2012-12-20 |
2014-06-26 |
Amgen Inc. |
Agonistes du récepteur apj et leurs utilisations
|
|
JO3519B1
(ar)
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
تركيبات أجسام مضادة لأجل cdh19 و cd3
|
|
EP2948478B1
(fr)
|
2013-01-25 |
2019-04-03 |
Amgen Inc. |
Anticorps ciblant cdh19 pour un mélanome
|
|
AU2014214037A1
(en)
|
2013-02-06 |
2015-07-02 |
Pieris Ag |
Novel lipocalin-mutein assays for measuring hepcidin concentration
|
|
SI2956476T1
(sl)
|
2013-02-18 |
2020-03-31 |
Vegenics Pty Limited |
Molekule za vezavo na ligande in uporabe le-teh
|
|
US9701743B2
(en)
|
2014-02-20 |
2017-07-11 |
Allergan, Inc. |
Complement component C5 antibodies
|
|
UY35397A
(es)
|
2013-03-12 |
2014-10-31 |
Amgen Inc |
INHIBIDORES POTENTES Y SELECTIVOS DE NaV1.7
|
|
US9546203B2
(en)
|
2013-03-14 |
2017-01-17 |
Amgen Inc. |
Aglycosylated Fc-containing polypeptides with cysteine substitutions
|
|
EP3421495A3
(fr)
|
2013-03-15 |
2019-05-15 |
Xencor, Inc. |
Modulation de cellules t avec des anticorps bispécifiques et des fusions fc
|
|
EP2970446A1
(fr)
|
2013-03-15 |
2016-01-20 |
Amgen Research (Munich) GmbH |
Constructions d'anticorps pour m2 et cd3 de grippe
|
|
US9260527B2
(en)
|
2013-03-15 |
2016-02-16 |
Sdix, Llc |
Anti-human CXCR4 antibodies and methods of making same
|
|
ES2993671T3
(en)
|
2013-03-15 |
2025-01-03 |
Univ Texas |
Peptide fttftvt for use in treating fibrosis
|
|
US20160122436A1
(en)
|
2013-03-15 |
2016-05-05 |
Amgen Research (Munich) Gmbh |
Single chain binding molecules comprising n-terminal abp
|
|
CN111138543B
(zh)
|
2013-03-15 |
2024-06-11 |
Xencor股份有限公司 |
异二聚体蛋白
|
|
KR101882366B1
(ko)
|
2013-05-30 |
2018-07-30 |
키닉사 파마슈티컬스, 리미티드 |
온코스타틴 m 수용체 항원 결합 단백질
|
|
EP3055695A1
(fr)
|
2013-09-12 |
2016-08-17 |
Institut National de la Santé et de la Recherche Médicale |
Procédé d'allo-anticorps de quantification in vitro, d'auto-anticorps et/ou d'anticorps thérapeutiques
|
|
EP4331605A3
(fr)
|
2013-09-13 |
2024-05-22 |
F. Hoffmann-La Roche AG |
Procedes et compositions comprenant des polypeptides recombinants purifies
|
|
TWI688401B
(zh)
|
2013-09-13 |
2020-03-21 |
美商安進公司 |
用於治療骨髓性白血病的表觀遺傳因子與靶向cd33及cd3之雙特異性化合物的組合
|
|
JP6546178B2
(ja)
|
2013-09-13 |
2019-07-17 |
ジェネンテック, インコーポレイテッド |
細胞株中の宿主細胞タンパク質及び組換えポリペプチド産物を検出及び定量化するための組成物並びに方法
|
|
RS61620B1
(sr)
|
2013-10-11 |
2021-04-29 |
Oxford Bio Therapeutics Ltd |
Konjugovana antitela prema ly75 za lečenje kancera
|
|
JP2017500319A
(ja)
|
2013-12-20 |
2017-01-05 |
ギリアード カリストガ エルエルシー |
(s)−2−(1−(9h−プリン−6−イルアミノ)プロピル)−5−フルオロ−3−フェニルキナゾリン−4(3h)−オンの塩酸塩の多形形態
|
|
MX2016008259A
(es)
|
2013-12-20 |
2016-10-13 |
Gilead Calistoga Llc |
Metodo de proceso para inhibidores de fosfatidilinositol 3-cinasa.
|
|
EP3094976B1
(fr)
|
2014-01-17 |
2020-03-25 |
Minomic International Ltd. |
Antigène de surface cellulaire du cancer de la prostate destiné au diagnostic
|
|
CN106232624B
(zh)
|
2014-02-27 |
2020-01-21 |
阿勒根公司 |
补体因子Bb抗体
|
|
KR102555955B1
(ko)
|
2014-03-27 |
2023-07-18 |
다케다 파머수티컬 컴패니 리미티드 |
당뇨병성 황반 부종의 치료를 위한 조성물 및 방법
|
|
LT3122781T
(lt)
|
2014-03-28 |
2020-03-25 |
Xencor, Inc. |
Bispecifiniai antikūnai, kurie jungiasi prie cd38 ir cd3
|
|
WO2015191781A2
(fr)
|
2014-06-10 |
2015-12-17 |
Amgen Inc. |
Polypeptides d'apéline
|
|
AU2015274696B2
(en)
|
2014-06-13 |
2018-09-27 |
Gilead Sciences, Inc. |
Phosphatidylinositol 3-kinase inhibitors
|
|
AR101669A1
(es)
|
2014-07-31 |
2017-01-04 |
Amgen Res Munich Gmbh |
Constructos de anticuerpos para cdh19 y cd3
|
|
TW201609812A
(zh)
|
2014-07-31 |
2016-03-16 |
安美基研究(慕尼黑)公司 |
最佳化之跨物種特異性雙特異性單鏈抗體構築體
|
|
US20170275373A1
(en)
|
2014-07-31 |
2017-09-28 |
Amgen Research (Munich) Gmbh |
Bispecific single chain antibody construct with enhanced tissue distribution
|
|
US10227411B2
(en)
|
2015-03-05 |
2019-03-12 |
Xencor, Inc. |
Modulation of T cells with bispecific antibodies and FC fusions
|
|
SG11201707186YA
(en)
|
2015-03-06 |
2017-10-30 |
Genentech Inc |
Ultrapurified dsba and dsbc and methods of making and using the same
|
|
WO2016149537A1
(fr)
|
2015-03-17 |
2016-09-22 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Protéine de prion du campagnol roussâtre utilisée comme substrat à large spectre pour détection et discrimination de souches de prions basées sur une conversion induite par agitation en temps réel (rt-quic)
|
|
IL283764B2
(en)
|
2015-04-10 |
2024-01-01 |
Amgen Inc |
Interleukin-2 muteins for the expansion of t-regulatory cells
|
|
CA2982682A1
(fr)
|
2015-04-17 |
2016-10-20 |
Amgen Research (Munich) Gmbh |
Constructions d'anticorps bispecifiques pour cdh3 et cd3
|
|
TWI717375B
(zh)
|
2015-07-31 |
2021-02-01 |
德商安美基研究(慕尼黑)公司 |
Cd70及cd3抗體構築體
|
|
TW202346349A
(zh)
|
2015-07-31 |
2023-12-01 |
德商安美基研究(慕尼黑)公司 |
Dll3及cd3抗體構築體
|
|
EA039859B1
(ru)
|
2015-07-31 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究(慕尼黑)公司 |
Egfrviii及cd3抗體構築體
|
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Flt3及cd3抗體構築體
|
|
TWI796283B
(zh)
|
2015-07-31 |
2023-03-21 |
德商安美基研究(慕尼黑)公司 |
Msln及cd3抗體構築體
|
|
EP3341415B1
(fr)
|
2015-08-28 |
2021-03-24 |
H. Hoffnabb-La Roche Ag |
Anticorps anti-hypusine et leurs utilisations
|
|
CN108602893A
(zh)
|
2015-12-11 |
2018-09-28 |
戴埃克斯有限公司 |
血浆激肽释放酶抑制剂及其治疗遗传性血管性水肿发作的用途
|
|
JOP20170017B1
(ar)
|
2016-01-25 |
2021-08-17 |
Amgen Res Munich Gmbh |
تركيب صيدلي يتضمن تركيبات جسم مضاد ثنائي الاختصاص
|
|
MA43959A
(fr)
|
2016-02-03 |
2018-12-12 |
Amgen Res Munich Gmbh |
Constructions d'anticorps impliquant des cellules t bispécifiques psma et cd3
|
|
JP6959011B2
(ja)
|
2016-02-03 |
2021-11-02 |
アムゲン リサーチ (ミュンヘン) ゲーエムベーハーAMGEN Research(Munich)GmbH |
Bcmaおよびcd3に対する二重特異性を有するt細胞エンゲージ抗体コンストラクト
|
|
JOP20170091B1
(ar)
|
2016-04-19 |
2021-08-17 |
Amgen Res Munich Gmbh |
إعطاء تركيبة ثنائية النوعية ترتبط بـ cd33 وcd3 للاستخدام في طريقة لعلاج اللوكيميا النخاعية
|
|
CN109071623B
(zh)
|
2016-05-04 |
2022-05-27 |
美国安进公司 |
用于扩增t调节性细胞的白细胞介素-2突变蛋白
|
|
SG11201809642TA
(en)
|
2016-05-16 |
2018-11-29 |
Baxalta Inc |
Anti-factor ix padua antibodies
|
|
CN117330747A
(zh)
|
2016-07-15 |
2024-01-02 |
武田药品工业株式会社 |
用于评估对于成浆细胞和浆细胞耗竭性疗法的应答的方法和材料
|
|
WO2018136553A1
(fr)
|
2017-01-18 |
2018-07-26 |
Genentech, Inc. |
Anticorps idiotypiques dirigés contre des anticorps anti-pd-l1 et leurs utilisations
|
|
JOP20190189A1
(ar)
|
2017-02-02 |
2019-08-01 |
Amgen Res Munich Gmbh |
تركيبة صيدلانية ذات درجة حموضة منخفضة تتضمن بنيات جسم مضاد يستهدف الخلية t
|
|
GB201703876D0
(en)
|
2017-03-10 |
2017-04-26 |
Berlin-Chemie Ag |
Pharmaceutical combinations
|
|
IL270239B2
(en)
|
2017-05-05 |
2025-01-01 |
Amgen Inc |
Pharmaceutical composition containing bispecific antibody constructs for improved storage and delivery
|
|
AU2018347521A1
(en)
|
2017-10-12 |
2020-05-07 |
Immunowake Inc. |
VEGFR-antibody light chain fusion protein
|
|
EA202091422A1
(ru)
|
2017-12-11 |
2020-08-28 |
Эмджен Инк. |
Способ непрерывного производства продуктов на основе биспецифических антител
|
|
UY38041A
(es)
|
2017-12-29 |
2019-06-28 |
Amgen Inc |
Construcción de anticuerpo biespecífico dirigida a muc17 y cd3
|
|
AR114437A1
(es)
|
2018-04-30 |
2020-09-02 |
Medimmune Ltd |
Conjugados para el direccionamiento hacia agregados y para la eliminación de los mismos
|
|
GB201809746D0
(en)
|
2018-06-14 |
2018-08-01 |
Berlin Chemie Ag |
Pharmaceutical combinations
|
|
JP7633810B2
(ja)
|
2018-07-02 |
2025-02-20 |
アムジェン インコーポレイテッド |
抗steap1抗原結合タンパク質
|
|
MA53325A
(fr)
|
2018-07-30 |
2021-06-09 |
Amgen Inc |
Administration prolongée d'une construction d'anticorps bispécifique se liant à cd33 et cd3
|
|
CN112789058A
(zh)
|
2018-10-11 |
2021-05-11 |
安进公司 |
双特异性抗体构建体的下游加工
|
|
WO2020081493A1
(fr)
|
2018-10-16 |
2020-04-23 |
Molecular Templates, Inc. |
Protéines de liaison pd-l1
|
|
CA3137494A1
(fr)
|
2019-06-13 |
2020-12-17 |
Amgen Inc. |
Commande de perfusion contenant de la biomasse automatisee dans la fabrication de produits biologiques
|
|
TW202120534A
(zh)
|
2019-08-13 |
2021-06-01 |
美商安進公司 |
用於擴增調節性t細胞之介白素-2突變蛋白
|
|
EP4028416A1
(fr)
|
2019-09-10 |
2022-07-20 |
Amgen Inc. |
Procédé de purification de polypeptides de liaison à un antigène bispécifique présentant une capacité de liaison dynamique de capture de protéine l améliorée
|
|
CA3156683A1
(fr)
|
2019-11-13 |
2021-05-20 |
Amgen Inc. |
Procede de reduction de la formation d'agregats dans le traitement en aval de molecules de liaison a l'antigene bispecifiques
|
|
PE20221506A1
(es)
|
2019-12-17 |
2022-10-04 |
Amgen Inc |
Agonista doble de interleucina-2/receptor de tnf para uso en terapia
|
|
JP2023510854A
(ja)
|
2020-01-13 |
2023-03-15 |
武田薬品工業株式会社 |
小児遺伝性血管性浮腫発作を治療するための血漿カリクレイン阻害剤及びその使用
|
|
CN115461375A
(zh)
|
2020-04-30 |
2022-12-09 |
基因泰克公司 |
Kras特异性抗体及其用途
|
|
US12312412B2
(en)
|
2020-05-19 |
2025-05-27 |
Amgen Inc. |
MAGEB2 binding constructs
|
|
MX2022014902A
(es)
|
2020-05-29 |
2023-01-04 |
Amgen Inc |
Administracion mitigadora de efectos adversos de un constructo biespecifico que se une a cd33 y cd3.
|
|
KR20230017822A
(ko)
|
2020-06-01 |
2023-02-06 |
제넨테크, 인크. |
세포외 소포를 만들기 위한 방법 및 이들의 용도
|
|
CN116670285A
(zh)
|
2020-06-23 |
2023-08-29 |
江苏康缘药业股份有限公司 |
抗cd38抗体及其用途
|
|
CA3188134A1
(fr)
|
2020-07-14 |
2022-01-20 |
F. Hoffmann-La Roche Ag |
Dosages pour des combinaisons de doses fixes
|
|
AU2021374839A1
(en)
|
2020-11-06 |
2023-06-08 |
Amgen Inc. |
Multitargeting bispecific antigen-binding molecules of increased selectivity
|
|
EP4314078A1
(fr)
|
2021-04-02 |
2024-02-07 |
Amgen Inc. |
Constructions de liaison à mageb2
|
|
WO2022234102A1
(fr)
|
2021-05-06 |
2022-11-10 |
Amgen Research (Munich) Gmbh |
Molécules de liaison à l'antigène ciblant cd20 et cd22 destinées à être utilisées dans des maladies prolifératives
|
|
CN113372514B
(zh)
*
|
2021-06-22 |
2022-06-14 |
安徽农业大学 |
一种刀豆蛋白聚合物水凝胶的制备方法、制得的水凝胶及其应用
|
|
WO2023218027A1
(fr)
|
2022-05-12 |
2023-11-16 |
Amgen Research (Munich) Gmbh |
Molécules bispécifiques multicibles à chaînes multiples de liaison à un antigène à sélectivité accrue
|
|
JP2025533434A
(ja)
|
2022-09-14 |
2025-10-07 |
アムジエン・インコーポレーテツド |
二重特異性分子安定化組成物
|
|
AU2024302269A1
(en)
|
2023-06-14 |
2025-11-13 |
Amgen Inc. |
T cell engager masking molecules
|