BRPI0907381A2 - Derivados de carboxamidas azabicíclicos, o respectivo preparo e a respectiva aplicação em terapêutica. - Google Patents

Derivados de carboxamidas azabicíclicos, o respectivo preparo e a respectiva aplicação em terapêutica.

Info

Publication number: BRPI0907381A2
Authority: BR; Brazil
Prior art keywords: preparation; therapeutic application; carboxamide derivatives; azabicyclic; azabicyclic carboxamide
Prior art date: 2008-01-22

Application number

BRPI0907381-7A

Other languages

English (en)

Inventor

Laurent Dubois

Yannick Evanno

David Machnik

André Malanda

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-01-22

Filing date

2009-01-20

Publication date

2015-07-14

2009-01-20 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2015-07-14 Publication of BRPI0907381A2 publication Critical patent/BRPI0907381A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Virology (AREA)
Dermatology (AREA)
Pain & Pain Management (AREA)
Communicable Diseases (AREA)
Psychiatry (AREA)
Ophthalmology & Optometry (AREA)
Oncology (AREA)
Obesity (AREA)
Reproductive Health (AREA)
Biotechnology (AREA)
Hematology (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Hospice & Palliative Care (AREA)
Pulmonology (AREA)
Endocrinology (AREA)
Molecular Biology (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

BRPI0907381-7A 2008-01-22 2009-01-20 Derivados de carboxamidas azabicíclicos, o respectivo preparo e a respectiva aplicação em terapêutica. BRPI0907381A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0800308A FR2926554B1 (fr)	2008-01-22	2008-01-22	Derives de carboxamides azabicycliques, leur preparation et leur application en therapeutique
PCT/FR2009/000052 WO2009112678A2 (fr)	2008-01-22	2009-01-20	Derives de carboxam i d es azabicycliques, leur preparation et leur application en therapeutique.

Publications (1)

Publication Number	Publication Date
BRPI0907381A2 true BRPI0907381A2 (pt)	2015-07-14

Family

ID=39843820

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0907381-7A BRPI0907381A2 (pt)	2008-01-22	2009-01-20	Derivados de carboxamidas azabicíclicos, o respectivo preparo e a respectiva aplicação em terapêutica.

Country Status (29)

Country	Link
US (1)	US8354425B2 (pt)
EP (1)	EP2235015B1 (pt)
JP (1)	JP5478512B2 (pt)
KR (1)	KR101593711B1 (pt)
CN (1)	CN101977911A (pt)
AR (1)	AR070206A1 (pt)
AU (1)	AU2009224533B2 (pt)
BR (1)	BRPI0907381A2 (pt)
CA (1)	CA2712609C (pt)
CO (1)	CO6280509A2 (pt)
CR (1)	CR11546A (pt)
DO (1)	DOP2010000213A (pt)
EA (1)	EA201070872A1 (pt)
EC (1)	ECSP10010337A (pt)
FR (1)	FR2926554B1 (pt)
HN (1)	HN2010001459A (pt)
IL (1)	IL207078A (pt)
MA (1)	MA32089B1 (pt)
MX (1)	MX2010007977A (pt)
MY (1)	MY150576A (pt)
NI (1)	NI201000124A (pt)
NZ (1)	NZ586938A (pt)
PA (1)	PA8812801A1 (pt)
PE (1)	PE20091320A1 (pt)
TW (1)	TWI428339B (pt)
UA (1)	UA102837C2 (pt)
UY (1)	UY31606A1 (pt)
WO (1)	WO2009112678A2 (pt)
ZA (1)	ZA201005202B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2926555B1 (fr)	2008-01-22	2010-02-19	Sanofi Aventis	Derives bicycliques de carboxamides azabicycliques, leur preparation et leur application en therapeutique
NZ587215A (en) *	2008-01-22	2012-08-31	Takeda Pharmaceutical	Tricyclic compounds having corticotropin-releasing factor antagonistic activity and pharmaceutical compositions containing them
AR090044A1 (es)	2011-12-21	2014-10-15	Novira Therapeutics Inc	Agentes antivirales para la hepatitis b
SG10201605291WA (en)	2012-08-28	2016-08-30	Janssen Sciences Ireland Uc	Sulfamoyl-arylamides and the use thereof as medicaments for the treatment of hepatitis b
JP6466348B2 (ja)	2013-02-28	2019-02-06	ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー	スルファモイル−アリールアミドおよびｂ型肝炎を処置するための医薬品としてのその使用
DK2981536T3 (en)	2013-04-03	2017-09-25	Janssen Sciences Ireland Uc	N-PHENYLC CARBOXAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICINES FOR THE TREATMENT OF HEPATITIS B
PT2997019T (pt)	2013-05-17	2018-11-21	Janssen Sciences Ireland Uc	Derivados de sulfamoíltiofenamida e o seu uso como medicamentos para o tratamento da hepatite b
JO3603B1 (ar)	2013-05-17	2020-07-05	Janssen Sciences Ireland Uc	مشتقات سلفامويل بيرولاميد واستخدامها كادوية لمعالجة التهاب الكبد نوع بي
NO3024819T3 (pt)	2013-07-25	2018-07-21
EA034448B1 (ru)	2013-10-23	2020-02-10	Янссен Сайенсиз Айрлэнд Юси	Производные карбоксамида и их применение в качестве медикаментов для лечения гепатита b
US9169212B2 (en)	2014-01-16	2015-10-27	Novira Therapeutics, Inc.	Azepane derivatives and methods of treating hepatitis B infections
US10392349B2 (en)	2014-01-16	2019-08-27	Novira Therapeutics, Inc.	Azepane derivatives and methods of treating hepatitis B infections
JP6466461B2 (ja)	2014-02-03	2019-02-06	ヴァイティーファーマシューティカルズ，インコーポレイテッド	Ｒｏｒガンマのジヒドロピロロピリジン阻害剤
EP3102225B1 (en)	2014-02-05	2020-03-25	Novira Therapeutics Inc.	Combination therapy for treatment of hbv infections
PL3102572T3 (pl)	2014-02-06	2019-04-30	Janssen Sciences Ireland Uc	Pochodne sulfamoilopirolamidu i ich zastosowanie jako leki do leczenia wirusowego zapalenia wątroby typu B
JP6564029B2 (ja)	2014-10-14	2019-08-21	ヴァイティーファーマシューティカルズ，エルエルシー	Ｒｏｒ−ガンマのジヒドロピロロピリジン阻害剤
US9845308B2 (en)	2014-11-05	2017-12-19	Vitae Pharmaceuticals, Inc.	Isoindoline inhibitors of ROR-gamma
US9663515B2 (en)	2014-11-05	2017-05-30	Vitae Pharmaceuticals, Inc.	Dihydropyrrolopyridine inhibitors of ROR-gamma
EA201792069A1 (ru)	2015-03-19	2018-04-30	Новира Терапьютикс, Инк.	Производные азокана и азонана и способы лечения инфекций гепатита в
US10875876B2 (en)	2015-07-02	2020-12-29	Janssen Sciences Ireland Uc	Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
EP3331876B1 (en)	2015-08-05	2020-10-07	Vitae Pharmaceuticals, LLC	Modulators of ror-gamma
WO2017059059A1 (en)	2015-09-29	2017-04-06	Novira Therapeutics, Inc.	Crystalline forms of a hepatitis b antiviral agent
MA53943A (fr)	2015-11-20	2021-08-25	Vitae Pharmaceuticals Llc	Modulateurs de ror-gamma
TW202220968A (zh)	2016-01-29	2022-06-01	美商維它藥物有限責任公司	ＲＯＲ－γ調節劑
JP2019511542A (ja)	2016-04-15	2019-04-25	ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー	カプシド集合阻害剤を含む組み合わせ及び方法
US9481674B1 (en)	2016-06-10	2016-11-01	Vitae Pharmaceuticals, Inc.	Dihydropyrrolopyridine inhibitors of ROR-gamma
WO2019018975A1 (en)	2017-07-24	2019-01-31	Vitae Pharmaceuticals, Inc.	INHIBITORS OF ROR GAMMA
SG11202000621VA (en)	2017-07-24	2020-02-27	Vitae Pharmaceuticals Llc	Inhibitors of ror?
EP3765011A1 (en)	2018-03-14	2021-01-20	Janssen Sciences Ireland Unlimited Company	Capsid assembly modulator dosing regimen
BR112021015618A2 (pt)	2019-02-22	2021-10-05	Janssen Sciences Ireland Unlimited Company	Derivados de amida úteis no tratamento da infecção pelo hbv ou doenças induzidas pelo hbv
MA55879A (fr)	2019-05-06	2022-03-16	Janssen Sciences Ireland Unlimited Co	Dérivés d'amide utiles dans le traitement d'une infection par le virus de l'hépatite b ou de maladies induites par le virus de l'hépatite b

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2677358B1 (fr)	1991-06-05	1994-09-30	Rhone Poulenc Chimie	Composes organosilyles et leur procede de synthese.
JP2001151771A (ja)	1999-09-10	2001-06-05	Kyowa Hakko Kogyo Co Ltd	含窒素芳香族複素環誘導体
EP2033953A1 (en)	2002-02-15	2009-03-11	Glaxo Group Limited	Vanilloid receptor modulators
US7338950B2 (en)	2003-10-07	2008-03-04	Renovis, Inc.	Amide compounds as ion channel ligands and uses thereof
JP2007518816A (ja)	2004-01-23	2007-07-12	アムジエン・インコーポレーテツド	バニロイド受容体リガンド及び炎症性及び神経因性疼痛の治療におけるこれらの使用
GB0403780D0 (en)	2004-02-20	2004-03-24	Astrazeneca Ab	Therapeutic agents
CA2566332A1 (en) *	2004-05-14	2005-11-24	Pfizer Products Inc.	Pyrimidine derivatives for the treatment of abnormal cell growth
FR2874015B1 (fr) *	2004-08-05	2006-09-15	Sanofi Synthelabo	Derives de n-(1h-indolyl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique
CA2581516C (en)	2004-10-12	2013-06-11	Astrazeneca Ab	Quinazoline derivatives
FR2880625B1 (fr) *	2005-01-07	2007-03-09	Sanofi Aventis Sa	Derives de n-(heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique
FR2888848B1 (fr) *	2005-07-22	2007-09-28	Sanofi Aventis Sa	Derives de n-(arylalkyl)-1h-pyrrrolopyridine-2-carboxamides, leur preparation et leur application en therapeutique
FR2888847B1 (fr) *	2005-07-22	2007-08-31	Sanofi Aventis Sa	Derives de n-(heteriaryl)-1-heteorarylalkyl-1h-indole-2- carboxamides, leur preparation et application en therapeutique
FR2897061B1 (fr)	2006-02-03	2010-09-03	Sanofi Aventis	Derives de n-heteroaryl-carboxamides tricycliques contenant un motif benzimidazole, leur preparation et leur application en therapeutique.
FR2904316B1 (fr) *	2006-07-31	2008-09-05	Sanofi Aventis Sa	Derives de n-(amino-heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique.
FR2910473B1 (fr) *	2006-12-26	2009-02-13	Sanofi Aventis Sa	Derives de n-(amino-heteroaryl)-1h-pyrrolopyridine-2- carboxamides, leur preparation et leur application en therapeutique.
FR2911605B1 (fr) *	2007-01-19	2009-04-17	Sanofi Aventis Sa	Derives de pyrrolopyridine-2-carbowamides, leur preparation et leur application en therapeutique
FR2911604B1 (fr) *	2007-01-19	2009-04-17	Sanofi Aventis Sa	Derives de n-(heteroaryl-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique
FR2926556B1 (fr) *	2008-01-22	2010-02-19	Sanofi Aventis	Derives de carboxamides n-azabicycliques, leur preparation et leur application en therapeutique
FR2926555B1 (fr) *	2008-01-22	2010-02-19	Sanofi Aventis	Derives bicycliques de carboxamides azabicycliques, leur preparation et leur application en therapeutique
FR2926553B1 (fr) *	2008-01-23	2010-02-19	Sanofi Aventis	Derives d'indole-2-carboxamides et d'azaindole-2- carboxamides substitues par un groupe silanyle, leur preparation et leur application en therapeutique

2008
- 2008-01-22 FR FR0800308A patent/FR2926554B1/fr not_active Expired - Fee Related
2009
- 2009-01-20 PE PE2009000064A patent/PE20091320A1/es not_active Application Discontinuation
- 2009-01-20 EP EP09719730.5A patent/EP2235015B1/fr not_active Not-in-force
- 2009-01-20 WO PCT/FR2009/000052 patent/WO2009112678A2/fr active Application Filing
- 2009-01-20 MX MX2010007977A patent/MX2010007977A/es active IP Right Grant
- 2009-01-20 CN CN2009801100023A patent/CN101977911A/zh active Pending
- 2009-01-20 AU AU2009224533A patent/AU2009224533B2/en not_active Ceased
- 2009-01-20 MY MYPI20103439 patent/MY150576A/en unknown
- 2009-01-20 EA EA201070872A patent/EA201070872A1/ru unknown
- 2009-01-20 NZ NZ586938A patent/NZ586938A/en not_active IP Right Cessation
- 2009-01-20 BR BRPI0907381-7A patent/BRPI0907381A2/pt not_active IP Right Cessation
- 2009-01-20 AR ARP090100166A patent/AR070206A1/es unknown
- 2009-01-20 CA CA2712609A patent/CA2712609C/fr not_active Expired - Fee Related
- 2009-01-20 KR KR1020107018566A patent/KR101593711B1/ko active Active
- 2009-01-20 JP JP2010543539A patent/JP5478512B2/ja not_active Expired - Fee Related
- 2009-01-20 UA UAA201010237A patent/UA102837C2/ru unknown
- 2009-01-21 TW TW098102268A patent/TWI428339B/zh not_active IP Right Cessation
- 2009-01-21 PA PA20098812801A patent/PA8812801A1/es unknown
- 2009-01-22 UY UY031606A patent/UY31606A1/es not_active Application Discontinuation
2010
- 2010-06-29 CR CR11546A patent/CR11546A/es not_active Application Discontinuation
- 2010-07-09 DO DO2010000213A patent/DOP2010000213A/es unknown
- 2010-07-12 EC EC2010010337A patent/ECSP10010337A/es unknown
- 2010-07-19 IL IL207078A patent/IL207078A/en not_active IP Right Cessation
- 2010-07-21 US US12/840,659 patent/US8354425B2/en not_active Expired - Fee Related
- 2010-07-21 NI NI201000124A patent/NI201000124A/es unknown
- 2010-07-21 ZA ZA2010/05202A patent/ZA201005202B/en unknown
- 2010-07-21 HN HN2010001459A patent/HN2010001459A/es unknown
- 2010-07-22 CO CO10089487A patent/CO6280509A2/es not_active Application Discontinuation
- 2010-08-17 MA MA33097A patent/MA32089B1/fr unknown

Also Published As

Publication number	Publication date
NZ586938A (en)	2012-06-29
EP2235015A2 (fr)	2010-10-06
PE20091320A1 (es)	2009-09-26
JP2011510050A (ja)	2011-03-31
TW200936585A (en)	2009-09-01
CA2712609A1 (fr)	2009-09-17
JP5478512B2 (ja)	2014-04-23
CR11546A (es)	2010-10-05
NI201000124A (es)	2010-12-17
EP2235015B1 (fr)	2016-08-24
AU2009224533B2 (en)	2013-12-05
FR2926554A1 (fr)	2009-07-24
EA201070872A1 (ru)	2011-02-28
KR101593711B1 (ko)	2016-02-12
IL207078A (en)	2015-09-24
ZA201005202B (en)	2011-09-28
CO6280509A2 (es)	2011-05-20
MX2010007977A (es)	2010-08-04
UA102837C2 (ru)	2013-08-27
CA2712609C (fr)	2016-03-08
HN2010001459A (es)	2013-07-29
KR20100105783A (ko)	2010-09-29
WO2009112678A3 (fr)	2009-12-30
CN101977911A (zh)	2011-02-16
TWI428339B (zh)	2014-03-01
MA32089B1 (fr)	2011-02-01
MY150576A (en)	2014-01-30
PA8812801A1 (es)	2009-08-26
US20110009364A1 (en)	2011-01-13
ECSP10010337A (es)	2010-08-31
AU2009224533A1 (en)	2009-09-17
UY31606A1 (es)	2009-08-31
IL207078A0 (en)	2010-12-30
AR070206A1 (es)	2010-03-25
FR2926554B1 (fr)	2010-03-12
WO2009112678A2 (fr)	2009-09-17
US8354425B2 (en)	2013-01-15
DOP2010000213A (es)	2010-07-31

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