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BRPI0821286A8 - Métodos e composições para imunizar porcos contra circovirus suino - Google Patents

Métodos e composições para imunizar porcos contra circovirus suino

Info

Publication number
BRPI0821286A8
BRPI0821286A8 BRPI0821286A BRPI0821286A BRPI0821286A8 BR PI0821286 A8 BRPI0821286 A8 BR PI0821286A8 BR PI0821286 A BRPI0821286 A BR PI0821286A BR PI0821286 A BRPI0821286 A BR PI0821286A BR PI0821286 A8 BRPI0821286 A8 BR PI0821286A8
Authority
BR
Brazil
Prior art keywords
porcine circovirus
compositions
methods
pigs against
porcine
Prior art date
Application number
BRPI0821286A
Other languages
English (en)
Inventor
Qitu Wu Stephen
Original Assignee
Wyeth Llc
Pah W Llc
Zoetis W Llc
Zoetis Services Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40436491&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0821286(A8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Llc, Pah W Llc, Zoetis W Llc, Zoetis Services Llc filed Critical Wyeth Llc
Publication of BRPI0821286A2 publication Critical patent/BRPI0821286A2/pt
Publication of BRPI0821286A8 publication Critical patent/BRPI0821286A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

MÉTODOS E COMPOSIÇÕES PARA IMUNIZAR PORCOS CONTRA CIRCOVÍRUS SUÍNO. A presente invenção refere-se ao isolamento e identificação de duas novas cepas de circovírus suíno do tipo 2B. Estas duas novas cepas de circovirus suíno podem ser usadas para a preparação de vacina ou composições imunogênicas para imunizar porcos contra a síndrome multissistêmica do definhamento do leitão desmamado (PMWS). Consequentemente, a invenção fornece métodos para evocar uma resposta imune protetora contra um circovírus suíno patogênico, através da administração de uma quantidade imunogenicamente eficaz de uma vacina ou composição imunogênica de circovírus suíno do tipo 2B ao um porco, compreendendo pelo menos um dos circovírus suínos tendo uma sequência de ácidos nucléicos, conforme apresentado na SEQ ID NOs: 1 ou 2, ou pelo menos uma proteína de pelo menos uma das duas novas cepas do tipo 2B de circovírus suíno, conforme descrito neste relatório. A invenção refere-se ainda à proteção de um porco a qualquer um ou mais dos sintomas ou sequelas associados com PMWS.
BRPI0821286A 2007-12-21 2008-12-18 Métodos e composições para imunizar porcos contra circovirus suino BRPI0821286A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1589407P 2007-12-21 2007-12-21
PCT/US2008/087361 WO2009085912A1 (en) 2007-12-21 2008-12-18 Methods and compositions for immunizing pigs against porcine circovirus

Publications (2)

Publication Number Publication Date
BRPI0821286A2 BRPI0821286A2 (pt) 2014-10-14
BRPI0821286A8 true BRPI0821286A8 (pt) 2017-08-15

Family

ID=40436491

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0821286A BRPI0821286A8 (pt) 2007-12-21 2008-12-18 Métodos e composições para imunizar porcos contra circovirus suino

Country Status (16)

Country Link
US (2) US20090162398A1 (pt)
EP (1) EP2225367A1 (pt)
JP (2) JP2011507522A (pt)
KR (1) KR20100094587A (pt)
CN (1) CN101932700A (pt)
AR (1) AR069882A1 (pt)
AU (1) AU2008343172B2 (pt)
BR (1) BRPI0821286A8 (pt)
CA (1) CA2710247C (pt)
CL (1) CL2008003813A1 (pt)
CO (1) CO6290791A2 (pt)
ME (1) ME01156B (pt)
NZ (1) NZ586238A (pt)
RU (1) RU2493254C9 (pt)
UA (1) UA99495C2 (pt)
WO (1) WO2009085912A1 (pt)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR078253A1 (es) 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
WO2011048215A1 (en) * 2009-10-22 2011-04-28 Universität Leipzig Detection of a circovirus in calves suffering from bovine neonatal pancytopenia
WO2011091389A2 (en) * 2010-01-25 2011-07-28 Blood Systems, Inc. Cyclovirus and method of use
CN102971425A (zh) 2010-03-16 2013-03-13 弗吉尼亚科技知识产权有限公司 活的减毒嵌合猪圆环病毒疫苗
KR101675185B1 (ko) * 2010-07-08 2016-11-10 유나이티드 바이오메디칼 인크. 디자이너(designer) 펩티드-기반 pcv2 백신
CN101920012B (zh) * 2010-07-22 2012-12-12 普莱柯生物工程股份有限公司 利用家蚕生物反应器生产猪圆环病毒2型重组衣壳蛋白亚单位疫苗的方法及其产品
KR101030792B1 (ko) * 2010-09-16 2011-04-27 주식회사 코미팜 돼지 써코바이러스２(ｐｃｖ２) 유전자의 표면발현용 벡터 및 이로 형질전환된 살모넬라 백신 균주
CN102199571B (zh) * 2011-04-06 2013-07-31 华中农业大学 一种表达猪2型圆环病毒orf2基因片段的重组支气管败血波氏杆菌株、疫苗及应用
CN102988978B (zh) * 2011-08-01 2016-02-03 普莱柯生物工程股份有限公司 含有猪圆环病毒2型抗原与副猪嗜血杆菌抗原的疫苗组合物及其制备方法与应用
HUP1100470A2 (en) 2011-08-30 2013-03-28 Mezoegazdasagi Biotechnologiai Kutatokoezpont Nanoparticle-based veterinary vaccine
EP2564869A1 (en) 2011-09-02 2013-03-06 Ceva Sante Animale Synthetic capsid proteins and uses thereof
CN103083655B (zh) * 2011-11-02 2015-08-26 普莱柯生物工程股份有限公司 预防和治疗猪圆环病毒2型、副猪嗜血杆菌和猪肺炎支原体感染的疫苗组合物及其制备方法
CN103033622B (zh) * 2011-12-26 2015-03-25 武汉中博生物股份有限公司 猪圆环病毒2型elisa抗原检测试剂盒及其制备方法和其应用
CN102517331A (zh) * 2011-12-26 2012-06-27 武汉中博生物股份有限公司 一种猪圆环病毒2型亚单位疫苗及其制备方法和其应用
US9474692B2 (en) 2012-01-13 2016-10-25 Boehringer Ingelheim Vetmedica Gmbh Kit for the preparation of a vaccinating agent
US9982239B2 (en) 2012-06-12 2018-05-29 Alternative Gene Expression S.L. Baculoviral DNA elements for the expression of recombinant proteins in a host cell
EP2884997B1 (en) 2012-08-17 2020-01-22 Intervet International B.V. An immunogenic composition of killed leptospira bacteria
CN102824634B (zh) * 2012-09-14 2014-03-19 范红结 表达猪圆环病毒2型Cap蛋白的重组猪痘病毒载体疫苗及其制备方法
CN103920146A (zh) * 2013-01-14 2014-07-16 普莱柯生物工程股份有限公司 猪圆环病毒ⅱ型与猪伪狂犬病二联疫苗及其制备方法和应用
BR102013001893B1 (pt) * 2013-01-25 2022-01-25 Fundação De Amparo À Pesquisa Do Estado De Minas Gerais - Fapemig Antígenos recombinantes do porcine circovirus 2 (pcv-2) para formulações vacinais, kit de diagnóstico e uso
EP2789346A1 (en) 2013-04-11 2014-10-15 CEVA Santé Animale SA Fusion polypeptides and vaccines
CN103275938B (zh) * 2013-05-07 2015-02-25 上海市农业科学院 猪圆环病毒弱毒疫苗株的制备方法
PL2994162T3 (pl) 2013-05-08 2021-10-18 Pharmgate Biologics Inc. Szczepionka przeciwko pcv2 i mykoplazmie
EP4176899A1 (en) 2013-08-23 2023-05-10 Boehringer Ingelheim Animal Health USA Inc. Porcine circovirus type 2 (pcv2) subunit vaccine
CA2925281C (en) 2013-09-25 2022-05-03 Zoetis Services Llc Pcv2b divergent vaccine composition and methods of use
ES2778425T3 (es) 2013-10-02 2020-08-10 Boehringer Ingelheim Animal Health Usa Inc Variante de la proteína ORF2 del PCV2 y partículas similares a virus compuestas por esta
CN104248759B (zh) * 2013-11-19 2017-05-10 普莱柯生物工程股份有限公司 一种疫苗组合物及其制备方法和应用
CN104250640A (zh) 2014-08-22 2014-12-31 普莱柯生物工程股份有限公司 猪伪狂犬病病毒基因缺失株、疫苗组合物及其制备方法和应用
CN105709220B (zh) * 2014-12-03 2020-03-31 普莱柯生物工程股份有限公司 用于猪圆环病毒与猪流感的疫苗组合物及制备方法和应用
EP3034609A1 (en) 2014-12-19 2016-06-22 Ceva Sante Animale Recombinant swinepox virus and vaccines
CN104984335A (zh) * 2015-07-14 2015-10-21 浙江诺倍威生物技术有限公司 猪圆环病毒双亚型orf2共表达载体构建及疫苗制备
WO2017066772A1 (en) * 2015-10-16 2017-04-20 Kansas State University Research Foundation Porcine circovirus type 3 immunogenic compositions and methods of making and using the same
SG11201805379QA (en) * 2015-12-28 2018-07-30 Merial Inc M hyo multivalent vaccine and uses thereof
CN105785037B (zh) * 2016-03-30 2017-09-19 中国农业科学院兰州兽医研究所 猪圆环病毒2型抗体快速检测层析试纸条及制备方法
EP3254692A1 (en) 2016-06-10 2017-12-13 Ceva Sante Animale Multivalent recombinant spv
CN106435016B (zh) * 2016-08-30 2019-07-26 中国农业科学院兰州兽医研究所 一种快速显色一步法检测猪圆环病毒2型的lamp试剂盒
CN107937354A (zh) * 2017-11-10 2018-04-20 南京天邦生物科技有限公司 2型猪圆环病毒及其应用
WO2019110822A1 (en) 2017-12-08 2019-06-13 Ceva Sante Animale Recombinant swinepox virus and vaccines
KR102133632B1 (ko) * 2018-03-29 2020-07-13 충남대학교산학협력단 재조합 돼지 써코바이러스 및 이를 포함하는 돼지 써코바이러스 감염 질환의 예방용 백신 조성물
MX2020013484A (es) 2018-06-11 2021-05-27 Ceva Sante Animale Vacunacion contra circovirus porcinos.
CN109381696A (zh) * 2018-08-27 2019-02-26 长沙创西生物科技有限公司 一种用于防治猪圆环病毒病的缓释微囊的制备方法
CN111088396A (zh) * 2019-11-14 2020-05-01 河南科技学院 一种同时检测副猪嗜血杆菌、猪细小病毒、猪圆环病毒2型的三重实时荧光pcr方法
RU2747468C1 (ru) * 2020-06-23 2021-05-05 Федеральное Казенное Предприятие "Щелковский Биокомбинат" Способ получения вакцины против цирковируса свиней (варианты)
CN113907044A (zh) * 2021-11-09 2022-01-11 福建省连江县刘氏兔业养殖场 一种抗病猪品系的培育方法及其应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0138854B1 (en) * 1983-03-08 1992-11-04 Chiron Mimotopes Pty. Ltd. Antigenically active amino acid sequences
US4567043A (en) * 1983-06-15 1986-01-28 American Home Products Corporation (Del.) Canine corona virus vaccine
US5238662A (en) * 1987-07-31 1993-08-24 Chevron Research Company Processes for recovering precious metals
US5147966A (en) * 1990-07-31 1992-09-15 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Polyimide molding powder, coating, adhesive and matrix resin
FR2769322B1 (fr) * 1997-10-03 2002-03-08 Merial Sas Nouveaux circovirus porcins, vaccins et reactifs de diagnostic
US6391314B1 (en) * 1997-10-03 2002-05-21 Merial Porcine circoviruses vaccines diagnostic reagents
UA78180C2 (uk) * 1997-10-03 2007-03-15 Меріаль Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти
FR2781159B1 (fr) * 1998-07-06 2000-10-06 Merial Sas Vaccin circovirus et parvovirus porcin
US20040062775A1 (en) * 1997-12-05 2004-04-01 Agence Francaise De Securite Sanitaire Des Aliments Circovirus sequences associated with piglet weight loss disease (PWD)
FR2772047B1 (fr) * 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
US6287856B1 (en) * 1998-03-13 2001-09-11 University Of Georgia Research Foundation, Inc. Vaccines against circovirus infections
PT1379671E (pt) * 2001-03-27 2009-07-20 Univ Saskatchewan Métodos de cultura de circovírus
US20030096377A1 (en) * 2001-06-28 2003-05-22 Virginia Tech Intellectual Properties, Inc. Differential PCR-RFLP assay for detecting and distinguishing between nonpathogenic PCV-1 and pathogenic PCV-2
US7279166B2 (en) * 2001-12-12 2007-10-09 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
US7276353B2 (en) * 2001-12-12 2007-10-02 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
PT2371383E (pt) * 2005-12-29 2015-11-24 Boehringer Ingelheim Vetmed Utilização de uma composição imunogénica de pcv2 para atenuar os sintomas clínicos em porcos

Also Published As

Publication number Publication date
BRPI0821286A2 (pt) 2014-10-14
CO6290791A2 (es) 2011-06-20
JP2011507522A (ja) 2011-03-10
CN101932700A (zh) 2010-12-29
US20110305725A1 (en) 2011-12-15
AU2008343172B2 (en) 2015-02-19
JP2017060473A (ja) 2017-03-30
RU2493254C9 (ru) 2013-12-20
KR20100094587A (ko) 2010-08-26
AR069882A1 (es) 2010-02-24
RU2010124791A (ru) 2012-01-27
RU2493254C2 (ru) 2013-09-20
US20090162398A1 (en) 2009-06-25
WO2009085912A1 (en) 2009-07-09
ME01156B (me) 2013-03-20
NZ586238A (en) 2012-10-26
EP2225367A1 (en) 2010-09-08
UA99495C2 (ru) 2012-08-27
CA2710247C (en) 2014-02-18
AU2008343172A1 (en) 2009-07-09
CL2008003813A1 (es) 2009-03-20
CA2710247A1 (en) 2009-07-09

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Legal Events

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B25A Requested transfer of rights approved

Owner name: PAH W LLC (US)

B25D Requested change of name of applicant approved

Owner name: ZOETIS W LLC (US)

B15K Others concerning applications: alteration of classification

Free format text: A CLASSIFICACAO ANTERIOR ERA: C12N 7/00

Ipc: C12N 7/00 (2006.01), A61K 39/12 (2006.01)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25A Requested transfer of rights approved

Owner name: ZOETIS SERVICES LLC (US)

B25G Requested change of headquarter approved

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B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07B Technical examination (opinion): publication cancelled [chapter 7.2 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]