BR112012028893A2 - composições imunoestimuladoras e de vacina - Google Patents
composições imunoestimuladoras e de vacinaInfo
- Publication number
- BR112012028893A2 BR112012028893A2 BR112012028893A BR112012028893A BR112012028893A2 BR 112012028893 A2 BR112012028893 A2 BR 112012028893A2 BR 112012028893 A BR112012028893 A BR 112012028893A BR 112012028893 A BR112012028893 A BR 112012028893A BR 112012028893 A2 BR112012028893 A2 BR 112012028893A2
- Authority
- BR
- Brazil
- Prior art keywords
- immunostimulatory
- vaccine compositions
- mananas
- provides
- present
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 230000003308 immunostimulating effect Effects 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 125000003172 aldehyde group Chemical group 0.000 abstract 1
- 238000001415 gene therapy Methods 0.000 abstract 1
- 238000002255 vaccination Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55583—Polysaccharides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
composições imunoestimuladoras e de vacina. a presente invenção fornece uma composição imunoestimuladora compreendendo mananas ,em que pelo menos 75% das mananas são maiores do que cerca de 1000 kda e/ou têm pelo menos 150 grupos aldeído .a presente invenção. a presente invenção também fornece a utilização desta composição em métodos de terapia de vacinação e de gene, juntamente com processos para sua preparação.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33308610P | 2010-05-10 | 2010-05-10 | |
AU2010901997A AU2010901997A0 (en) | 2010-05-10 | Immunostimulatory and vaccine compositions | |
AU2010904060A AU2010904060A0 (en) | 2010-09-09 | Immunostimulatory and vaccine compositions | |
PCT/AU2011/000542 WO2011140595A2 (en) | 2010-05-10 | 2011-05-10 | Immunostimulatory and vaccine compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112012028893A2 true BR112012028893A2 (pt) | 2017-12-12 |
Family
ID=44914748
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112012028893A BR112012028893A2 (pt) | 2010-05-10 | 2011-05-10 | composições imunoestimuladoras e de vacina |
Country Status (9)
Country | Link |
---|---|
US (1) | US9597392B2 (pt) |
EP (1) | EP2574170A4 (pt) |
JP (1) | JP6096111B2 (pt) |
CN (1) | CN102985095B (pt) |
AU (1) | AU2011226992B2 (pt) |
BR (1) | BR112012028893A2 (pt) |
CA (1) | CA2798856C (pt) |
RU (1) | RU2578420C2 (pt) |
WO (1) | WO2011140595A2 (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3061462B1 (en) | 2007-07-02 | 2019-02-27 | Etubics Corporation | Methods and compositions for producing an adenovirus vector for use with multiple vaccinations |
JP2014532799A (ja) * | 2011-11-09 | 2014-12-08 | アセンド・バイオファーマシューティカルズ・リミテッド | 免疫調節結合体 |
WO2014031178A1 (en) | 2012-08-24 | 2014-02-27 | Etubics Corporation | Replication defective adenovirus vector in vaccination |
ES2503516B1 (es) | 2013-04-03 | 2015-09-09 | Inmunotek, S.L. | Complejo inmunogénico para vacunación y método de obtención |
AU2016205215B2 (en) | 2015-01-09 | 2021-03-11 | Etubics Corporation | Methods and compositions for combination immunotherapy |
EP3256140B1 (en) | 2015-01-09 | 2020-04-01 | Etubics Corporation | Compositions for ebola virus vaccination |
WO2016172249A1 (en) * | 2015-04-20 | 2016-10-27 | Etubics Corporation | Methods and compositions for combination immunotherapy |
AU2017291321B2 (en) | 2016-06-22 | 2020-06-18 | Alkermes, Inc. | Compositions and methods for modulating IL-10 immunostimulatory and anti-inflammatory properties |
KR20210044805A (ko) * | 2018-08-06 | 2021-04-23 | 닐슨 바이오사이언스, 아이엔씨. | 사마귀의 치료 |
US11197910B1 (en) * | 2020-08-19 | 2021-12-14 | Vitruviae LLC | Fusion proteins for the diagnosis, prophylaxis and treatment of infectious diseases |
AU2022234358A1 (en) * | 2021-03-12 | 2023-10-19 | Children's Medical Center Corporation | Polysaccharide adjuvants for virus vaccines |
CN113616799B (zh) * | 2021-07-13 | 2023-08-29 | 中国科学院长春应用化学研究所 | 一种疫苗载体、其制备方法及应用 |
WO2024117232A1 (ja) * | 2022-11-30 | 2024-06-06 | 国立大学法人九州大学 | 免疫原性複合体及び医薬組成物 |
Family Cites Families (37)
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US3362951A (en) | 1965-12-21 | 1968-01-09 | Farkas Alexander | Polysaccharide product derived from the juice of the aloe plant and methods for preparing same |
US5308838A (en) | 1982-05-07 | 1994-05-03 | Carrington Laboratories, Inc. | Uses of aloe products |
US4735935A (en) | 1985-12-17 | 1988-04-05 | Carrington Laboratories, Inc. | Process for preparation of aloe products products, produced thereby and compositions thereof |
US4861761A (en) | 1984-06-28 | 1989-08-29 | Dr. Madis Laboratories, Inc. | Aloeferon isolation, manufacturing and its applications |
FR2573656B1 (fr) | 1984-11-29 | 1987-02-27 | Sanofi Sa | Medicament comportant en tant qu'association au moins une immunotoxine et au moins un polymere contenant du mannose |
CA1339204C (en) | 1987-01-07 | 1997-08-05 | Joyce Taylor-Papadimitriou | Mucin core polypeptide, antibodies and probes |
US6054438A (en) | 1987-01-07 | 2000-04-25 | Imperial Cancer Research Technology Limited | Nucleic acid fragments encoding portions of the core protein of the human mammary epithelial mucin |
US5643578A (en) | 1992-03-23 | 1997-07-01 | University Of Massachusetts Medical Center | Immunization by inoculation of DNA transcription unit |
US5744144A (en) | 1993-07-30 | 1998-04-28 | University Of Pittsburgh University Patent Committee Policy And Procedures | Synthetic multiple tandem repeat mucin and mucin-like peptides, and uses thereof |
AUPM322393A0 (en) | 1993-12-24 | 1994-01-27 | Austin Research Institute, The | Mucin carbohydrate compounds and their use in immunotherapy |
EP0740704A1 (en) | 1994-01-27 | 1996-11-06 | University Of Massachusetts Medical Center | Immunization by inoculation of dna transcription unit |
US5939400A (en) | 1996-02-26 | 1999-08-17 | The Board Of Trustees Of The Leland Stanford Junior University | DNA vaccination for induction of suppressive T cell response |
WO1997044446A1 (en) | 1996-05-24 | 1997-11-27 | University Of Maryland At Baltimore | Dna vaccines for eliciting a mucosal immune response |
US5824659A (en) | 1996-09-04 | 1998-10-20 | Board Of Regents, The University Of Texas System | Cytoprotective oligosaccharide from Aloe preventing damage to the skin immune system by UV radiation |
CA2275259C (en) | 1996-12-20 | 2008-02-12 | Merck & Co., Inc. | Formulations of recombinant papillomavirus vaccines |
ES2357960T3 (es) | 1997-05-08 | 2011-05-04 | Oncothyreon Inc. | Procedimiento para generar células t activadas y células presentadoras de antígenos pulsadas con antígenos. |
US6573245B1 (en) | 1998-04-28 | 2003-06-03 | Galenica Pharmaceuticals, Inc. | Modified polysaccharide adjuvant-protein antigen conjugates, the preparation thereof and the use thereof |
IL125608A0 (en) | 1998-07-30 | 1999-03-12 | Yeda Res & Dev | Tumor associated antigen peptides and use of same as anti-tumor vaccines |
DE19917195B4 (de) | 1999-04-16 | 2006-09-28 | Immatics Biotechnologies Gmbh | Peptid zur Auslösung einer Immunreaktion gegen Tumorzellen, diese enthaltende pharmzeutische Zusammensetzungen, dessen Verwendungen, dafür codierende Nukleinsäure und diese Nukleinsäure enthaltender Expressionsvektor |
EP1210430B1 (en) | 1999-09-08 | 2006-08-30 | Transgene S.A. | Muc-1 derived peptides |
CA2399026A1 (en) | 2000-02-01 | 2001-08-09 | The Austin Research Institute | Mucin-1 derived antigens and their use in immunotherapy |
WO2008037033A1 (en) | 2006-09-29 | 2008-04-03 | The Macfarlane Burnet Institute For Medical Research And Public Health Limited | Flu vaccine admixture of mannan and flu antigen |
AUPQ797700A0 (en) | 2000-06-06 | 2000-06-29 | Austin Research Institute, The | Vaccine |
AU2002218748A1 (en) | 2000-07-10 | 2002-01-21 | The University Of Mississippi | High molecular weight polysaccharide fraction from aloe vera with immunostimulatory activity |
ES2220800T3 (es) * | 2000-08-10 | 2004-12-16 | Ocean Nutrition Canada Ltd. | Preparaciones de chlorella que muestran propiedades inmunomoduladoras. |
ES2355819T3 (es) | 2002-08-15 | 2011-03-31 | 3M Innovative Properties Company | Composiciones inmunoestimuladoras y métodos para estimular una respuesta inmune. |
EP2181595A1 (en) | 2002-08-16 | 2010-05-05 | Yeda Research And Development Company Ltd. | Tumor associated antigen, peptides thereof, and use of same as anti-tumor vaccines |
WO2005044861A1 (en) * | 2003-10-31 | 2005-05-19 | Wyeth Holdings Corporation | Polysaccharides of helicobacter pylori |
EP1697515A4 (en) | 2003-11-12 | 2008-02-06 | Austin Research Inst | CONJUGATE DNA-EXCIPIENT |
US20060084629A1 (en) | 2004-10-15 | 2006-04-20 | Alvin Needleman | Immune system activating formula composed of selected long chain polysaccharides from natural sources |
JP2006241023A (ja) * | 2005-03-01 | 2006-09-14 | Asahi Breweries Ltd | 消化管組織における抗菌ペプチドの発現誘導または産生促進剤 |
JP2006241020A (ja) * | 2005-03-01 | 2006-09-14 | Asahi Breweries Ltd | 免疫系賦活剤 |
EP3085373A1 (en) | 2006-02-22 | 2016-10-26 | 3M Innovative Properties Company | Immune response modifier conjugates |
CA2648099C (en) | 2006-03-31 | 2012-05-29 | The Brigham And Women's Hospital, Inc | System for targeted delivery of therapeutic agents |
EP2046812A4 (en) | 2006-07-25 | 2010-04-14 | 4G Vaccines Pty Ltd | A CANCER VACCINE CONTAINING PEPTIDE DERIVED FROM MUCIN-1 (MUC1) T-CELL EPITOP |
US20080152648A1 (en) | 2006-09-26 | 2008-06-26 | Alexion Pharmaceuticals, Inc. | Compositions and methods for enhancing an adjuvant |
US20080149123A1 (en) | 2006-12-22 | 2008-06-26 | Mckay William D | Particulate material dispensing hairbrush with combination bristles |
-
2011
- 2011-05-10 WO PCT/AU2011/000542 patent/WO2011140595A2/en active Application Filing
- 2011-05-10 US US13/696,853 patent/US9597392B2/en not_active Expired - Fee Related
- 2011-05-10 JP JP2013509404A patent/JP6096111B2/ja not_active Expired - Fee Related
- 2011-05-10 CA CA2798856A patent/CA2798856C/en not_active Expired - Fee Related
- 2011-05-10 AU AU2011226992A patent/AU2011226992B2/en not_active Ceased
- 2011-05-10 EP EP11779973.4A patent/EP2574170A4/en not_active Withdrawn
- 2011-05-10 BR BR112012028893A patent/BR112012028893A2/pt not_active Application Discontinuation
- 2011-05-10 RU RU2012152952/15A patent/RU2578420C2/ru not_active IP Right Cessation
- 2011-05-10 CN CN201180033660.4A patent/CN102985095B/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU2011226992A1 (en) | 2011-11-24 |
CN102985095B (zh) | 2016-05-18 |
WO2011140595A3 (en) | 2012-01-05 |
RU2578420C2 (ru) | 2016-03-27 |
CA2798856C (en) | 2019-04-23 |
US20130251741A1 (en) | 2013-09-26 |
CA2798856A1 (en) | 2011-11-17 |
EP2574170A4 (en) | 2013-11-20 |
EP2574170A2 (en) | 2013-04-03 |
CN102985095A (zh) | 2013-03-20 |
US9597392B2 (en) | 2017-03-21 |
RU2012152952A (ru) | 2014-06-20 |
AU2011226992B2 (en) | 2012-03-22 |
WO2011140595A2 (en) | 2011-11-17 |
JP2013527854A (ja) | 2013-07-04 |
JP6096111B2 (ja) | 2017-03-15 |
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Legal Events
Date | Code | Title | Description |
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
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B07E | Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 10A ANUIDADE. |
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B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] |