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BRPI0413403A - método para produzir ácido succìnico - Google Patents

método para produzir ácido succìnico

Info

Publication number
BRPI0413403A
BRPI0413403A BRPI0413403-6A BRPI0413403A BRPI0413403A BR PI0413403 A BRPI0413403 A BR PI0413403A BR PI0413403 A BRPI0413403 A BR PI0413403A BR PI0413403 A BRPI0413403 A BR PI0413403A
Authority
BR
Brazil
Prior art keywords
succinic acid
produced
react
allowing
raw material
Prior art date
Application number
BRPI0413403-6A
Other languages
English (en)
Inventor
Makoto Murase
Ryusuke Aoyama
Miki Ikuta
Kenji Yamagishi
Mika Moriya
Jun Nakamura
Hiroyuki Kojima
Original Assignee
Mitsubishi Chem Corp
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Chem Corp, Ajinomoto Kk filed Critical Mitsubishi Chem Corp
Publication of BRPI0413403A publication Critical patent/BRPI0413403A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"MéTODO PARA PRODUZIR áCIDO SUCCìNICO". Produz-se o ácido succínico permitindo que uma bactéria modificada para intensificar -a atividade da fumarato reductase, ou uma preparação celular da mesma reaja com uma matéria prima orgânica em uma solução de reação contendo um entre um íon carbonato, um íon bicarbonato e gás dióxido de carbono para gerar ácido, succínico. Mais preferivelmente, o ácido succínico é produzido permitindo-se que uma bactéria modificada para intensificar as atividades da fumarato reductase e da piruvato carboxilase e reduzir a atividade da lactato deidrogenase, ou uma preparação celular da mesma, reaja com uma matéria prima orgânica em uma solução de reação contendo um entre um íon carbonato, um íon bicarbonato e gás dióxido de carbono para gerar ácido succínico. O ácido succínico é obtido coletando-se o ácido succínico produzido.
BRPI0413403-6A 2003-08-28 2004-08-27 método para produzir ácido succìnico BRPI0413403A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003304443 2003-08-28
PCT/JP2004/012404 WO2005021770A1 (ja) 2003-08-28 2004-08-27 コハク酸の製造方法

Publications (1)

Publication Number Publication Date
BRPI0413403A true BRPI0413403A (pt) 2006-10-17

Family

ID=34269270

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0413403-6A BRPI0413403A (pt) 2003-08-28 2004-08-27 método para produzir ácido succìnico

Country Status (5)

Country Link
US (1) US7763447B2 (pt)
EP (1) EP1672077B1 (pt)
CN (1) CN100575496C (pt)
BR (1) BRPI0413403A (pt)
WO (1) WO2005021770A1 (pt)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4469568B2 (ja) 2003-07-09 2010-05-26 三菱化学株式会社 有機酸の製造方法
CN100575496C (zh) 2003-08-28 2009-12-30 三菱化学株式会社 产生琥珀酸的方法
WO2005026349A1 (ja) 2003-09-17 2005-03-24 Mitsubishi Chemical Corporation 非アミノ有機酸の製造方法
BRPI0414764B8 (pt) * 2003-09-30 2018-09-18 Ajinomoto Kk método para purificar ácido succínico à partir de caldo de fermentação
WO2005113744A1 (ja) 2004-05-20 2005-12-01 Ajinomoto Co., Inc. コハク酸生産菌及びコハク酸の製造方法
JP5572279B2 (ja) * 2004-05-20 2014-08-13 味の素株式会社 コハク酸生産菌及びコハク酸の製造方法
EP1882712B1 (en) * 2005-04-22 2010-04-21 Mitsubishi Chemical Corporation Biomass-resource-derived polyester and production process thereof
JP4760121B2 (ja) * 2005-05-17 2011-08-31 三菱化学株式会社 コハク酸の製造方法
WO2007046389A1 (ja) 2005-10-18 2007-04-26 Ajinomoto Co., Inc. コハク酸の製造方法
US7993888B2 (en) 2006-02-24 2011-08-09 Mitsubishi Chemical Corporation Bacterium having enhanced 2-oxoglutarate dehydrogenase activity
KR100780324B1 (ko) * 2006-07-28 2007-11-29 한국과학기술원 신규 순수 숙신산 생성 변이 미생물 및 이를 이용한 숙신산제조방법
JP2010041920A (ja) 2006-12-19 2010-02-25 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
WO2008126896A1 (ja) 2007-04-10 2008-10-23 Ajinomoto Co., Inc. 有機酸の製造方法
WO2008133131A1 (ja) 2007-04-16 2008-11-06 Ajinomoto Co., Inc. 有機酸の製造方法
CN101688176B (zh) 2007-04-17 2013-11-06 味之素株式会社 具有羧基的酸性物质的生产方法
DE102007019184A1 (de) * 2007-04-20 2008-10-23 Organo Balance Gmbh Mikroorganismus zur Herstellung von Bernsteinsäure
WO2008143015A1 (ja) 2007-05-18 2008-11-27 Ajinomoto Co., Inc. コハク酸およびコハク酸アンモニウム溶液の製造方法
EP2192189B1 (en) * 2007-08-23 2018-08-22 Mitsubishi Chemical Corporation Method for production of succinic acid at high temperatures
DE102007047206B4 (de) * 2007-10-02 2016-08-11 Insilico Biotechnology Ag Biotechnologische Fixierung von Kohlenstoffdioxid
WO2009065778A1 (en) 2007-11-20 2009-05-28 Dsm Ip Assets B.V. Succinic acid production in a eukaryotic cell
US8735112B2 (en) 2007-11-20 2014-05-27 Dsm Ip Assets B.V. Dicarboxylic acid production in a recombinant yeast
EP2241630B1 (en) 2007-12-06 2016-06-01 Ajinomoto Co., Inc. A method for producing an organic acid
CN102781900A (zh) 2009-12-31 2012-11-14 麦兰特公司 从含有琥珀酸铵的发酵液纯化琥珀酸
BR112012022486A2 (pt) 2010-03-09 2015-10-06 Mitsubishi Chem Corp método de produção de ácido sucínico
US20130130339A1 (en) 2010-07-31 2013-05-23 Myriant Corporation Fermentation process for the production of organic acids
CN102249889B (zh) * 2010-12-13 2014-07-23 日照金禾博源生化有限公司 一种从柠檬酸母液中提取丁二酸的方法
EP2687591B1 (en) 2011-03-18 2021-01-06 Mitsubishi Chemical Corporation Method for producing polymer, method for producing organic acid, and organic acid-producing microorganism
WO2013069786A1 (ja) * 2011-11-11 2013-05-16 三菱化学株式会社 コハク酸の製造方法
MY173771A (en) 2011-11-11 2020-02-20 Ajinomoto Kk A method for producing a target substance by fermentation
KR20140066553A (ko) 2012-11-23 2014-06-02 삼성전자주식회사 코리네박테리움 속 균주의 신규 프로모터
JP2014150748A (ja) * 2013-02-06 2014-08-25 Sekisui Chem Co Ltd 変異微生物、並びに、コハク酸の生産方法
JP2016165225A (ja) 2013-07-09 2016-09-15 味の素株式会社 有用物質の製造方法
KR20150112575A (ko) 2014-03-28 2015-10-07 삼성전자주식회사 GlnD 또는 GlnK의 활성이 증가되도록 유전적으로 조작된 박테리아 세포 및 그를 이용하여 유기산을 생산하는 방법
CN104975050B (zh) * 2014-04-10 2019-01-01 中国石化扬子石油化工有限公司 一种富马酸的制备方法
JP2017216881A (ja) 2014-12-26 2017-12-14 味の素株式会社 ジカルボン酸の製造方法
CN105754963A (zh) * 2016-05-19 2016-07-13 江南大学 一种提高延胡索酸产量的方法
CN111073864B (zh) * 2018-10-19 2022-06-28 中国科学院天津工业生物技术研究所 提高苹果酸产量的新突变蛋白
CN113046283B (zh) * 2021-03-01 2023-06-13 江南大学 一株通过还原tca途径生产己二酸的工程菌株及其构建方法

Family Cites Families (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6696561B1 (en) 1909-07-09 2004-02-24 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding proteins involved in membrane synthesis and membrane transport
JPS57134500A (en) 1981-02-12 1982-08-19 Kyowa Hakko Kogyo Co Ltd Plasmid pcg1
JPS57183799A (en) 1981-04-17 1982-11-12 Kyowa Hakko Kogyo Co Ltd Novel plasmid
JPS5835197A (ja) 1981-08-26 1983-03-01 Kyowa Hakko Kogyo Co Ltd プラスミドｐｃｇ２
ZA816779B (en) 1981-09-30 1982-09-29 American Cyanamid Co Process for trimerizing isocyanic acid to make cyanuric acid
JPS5867679A (ja) 1981-09-30 1983-04-22 アメリカン・サイアナミド・カンパニ− イソシアン酸を三量化してシアヌル酸をつくる方法
JPS5877895A (ja) 1981-11-02 1983-05-11 Ajinomoto Co Inc プラスミドｐｈｍ１５１９
JPS58192900A (ja) 1982-05-04 1983-11-10 Ajinomoto Co Inc 複合プラスミド
JPS61209596A (ja) 1985-03-12 1986-09-17 Kanegafuchi Chem Ind Co Ltd 固定化微生物による有機酸の製法
JPH0636746B2 (ja) 1985-08-24 1994-05-18 味の素株式会社 Ｌ―グルタミン酸の製造方法
JPH0796522B2 (ja) 1986-04-08 1995-10-18 軽質留分新用途開発技術研究組合 カルボン酸アンモニウム水溶液からのカルボン酸の製造法
JPS62238232A (ja) 1986-04-09 1987-10-19 Res Assoc Util Of Light Oil カルボン酸アンモニウム水溶液からのカルボン酸の製造法
US5143834A (en) 1986-06-11 1992-09-01 Glassner David A Process for the production and purification of succinic acid
US5168055A (en) 1986-06-11 1992-12-01 Rathin Datta Fermentation and purification process for succinic acid
ES2036188T3 (es) 1986-06-11 1993-05-16 Michigan Biotechnology Institute Un procedimiento para la produccion de acido succinico por fermentacion anaerobia.
JPH01191686A (ja) 1988-01-26 1989-08-01 Mitsubishi Petrochem Co Ltd 複合プラスミド
JP2678995B2 (ja) 1988-09-08 1997-11-19 三菱化学株式会社 トリプトフアンシンターゼの製造法
US5185262A (en) 1988-07-27 1993-02-09 Mitsubishi Petrochemical Co., Ltd. DNA fragment containing gene which encodes the function of stabilizing plasmid in host microorganism
US5034105A (en) 1989-07-27 1991-07-23 Michigan Biotechnology Institute Carboxylic acid purification and crystallization process
JP2820279B2 (ja) 1989-08-11 1998-11-05 日本合成化学工業株式会社 ソルビン酸の製造方法
JP2973446B2 (ja) 1990-01-11 1999-11-08 三菱化学株式会社 新規プラスミドベクター
US5142834A (en) 1990-07-12 1992-09-01 Donnelly Corporation Vehicle trim assembly and fastener therefor
US5132456A (en) 1991-05-07 1992-07-21 The Regents Of The University Of California Sorption of carboxylic acid from carboxylic salt solutions at PHS close to or above the pKa of the acid, with regeneration with an aqueous solution of ammonia or low-molecular-weight alkylamine
JP2526836B2 (ja) 1991-08-23 1996-08-21 味の素株式会社 酢酸資化性遺伝子
JP3151884B2 (ja) 1991-12-03 2001-04-03 大日本インキ化学工業株式会社 ポリウレタンポリ尿素粒子
US5363179A (en) * 1993-04-02 1994-11-08 Rexham Graphics Inc. Electrographic imaging process
CA2126365C (en) 1993-07-06 1999-08-24 Steven W. Felman Recovery of citric acid from impure process streams by addition of strong acids and salts thereof
JP2844511B2 (ja) 1993-09-02 1999-01-06 味の素株式会社 酢酸資化性遺伝子及びその利用
JP3394593B2 (ja) 1994-05-11 2003-04-07 昭和高分子株式会社 生分解性脂肪族ポリエステルの製造方法
BR9508022A (pt) 1994-06-14 2002-05-21 Ajinomoto Kk Bactéria corineforme produtora de ácido l-glutâmico, processo para produzir ácido l-glutâmico, gene codificando para uma enzima, dna recombinante, bactéria corineforme, e, processo para produzir l-lisina
JP3210184B2 (ja) 1994-08-12 2001-09-17 明健株式会社 火山灰の精製方法および火山灰用分級装置
US5504004A (en) 1994-12-20 1996-04-02 Michigan Biotechnology Institute Process for making succinic acid, microorganisms for use in the process and methods of obtaining the microorganisms
US5869301A (en) 1995-11-02 1999-02-09 Lockhead Martin Energy Research Corporation Method for the production of dicarboxylic acids
US5770435A (en) 1995-11-02 1998-06-23 University Of Chicago Mutant E. coli strain with increased succinic acid production
JP3072891B2 (ja) 1996-08-14 2000-08-07 川崎製鉄株式会社 熱間圧延巻取装置における抜取異常処置方法
JP4168463B2 (ja) 1996-12-05 2008-10-22 味の素株式会社 Ｌ−リジンの製造法
KR19990013007A (ko) 1997-07-31 1999-02-25 박원훈 형질전환된 대장균 ｓｓ373(ｋｃｔｃ 8818ｐ)과 이를 이용한숙신산의 생산방법
US5958744A (en) 1997-08-18 1999-09-28 Applied Carbochemicals Succinic acid production and purification
JP4197754B2 (ja) 1997-10-09 2008-12-17 三菱化学株式会社 乳酸又はコハク酸の製造方法
JP3480274B2 (ja) 1997-10-29 2003-12-15 三菱化学株式会社 脂肪族ポリエステル共重合体の製造方法
JPH11196887A (ja) 1998-01-16 1999-07-27 Mitsubishi Chemical Corp ホスホエノールピルビン酸カルボキシラーゼ遺伝子組み換え菌体による有機酸の製造法
JP3967812B2 (ja) 1998-01-16 2007-08-29 三菱化学株式会社 ピルビン酸カルボキシラーゼ遺伝子組み換え菌体による有機酸の製造法
JP4074365B2 (ja) 1998-01-28 2008-04-09 三菱化学株式会社 ラクテートデヒドロゲナーゼ遺伝子及び該遺伝子破壊株
US20030087381A1 (en) 1998-04-13 2003-05-08 University Of Georgia Research Foundation, Inc. Metabolically engineered organisms for enhanced production of oxaloacetate-derived biochemicals
EP2194122B1 (en) 1998-04-13 2015-12-02 The University Of Georgia Research Foundation, Inc. Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells
JP4132253B2 (ja) 1998-07-24 2008-08-13 株式会社武蔵野化学研究所 アンモニア耐性ｌ（＋）−乳酸産生能菌およびｌ（＋）−乳酸の生産方法
DE19951975A1 (de) 1999-10-28 2001-05-03 Degussa Neue für das poxB-Gen codierende Nuleotidsequenzen
DE19959650A1 (de) * 1999-12-10 2001-06-13 Degussa Neue für die Gene sdhA, sdhB und sdhC codierende Nukleotidsequenzen
JP4623825B2 (ja) 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド
US6670505B1 (en) 2000-03-07 2003-12-30 Eastman Chemical Company Process for the recovery of organic acids from aqueous solutions
DE10044681A1 (de) * 2000-09-09 2002-03-21 Degussa Neue für das lldD2-Gen kodierende Nukleotidsequenzen
US6911329B2 (en) 2000-09-23 2005-06-28 Degussa Ag Process for the fermentative preparation of D-pantothenic acid using coryneform bacteria
ATE274575T1 (de) 2000-09-30 2004-09-15 Degussa Prozess zur fermentativen herstellung von d- pantothensäure mit coryneformen bakterien
EP1330526B1 (en) 2000-11-04 2010-04-21 Evonik Degussa GmbH Process for the fermentative preparation of l-amino acids using strains of the enterobacteriaceae family
DE10112102A1 (de) 2001-03-14 2002-09-19 Degussa Verfahren zur fermentativen Herstellung von D-Pantothensäure und/oder deren Salzen
JP2002291477A (ja) * 2001-03-30 2002-10-08 Mitsubishi Chemicals Corp フマラーゼをコードするｄｎａ及びその利用
US6743610B2 (en) 2001-03-30 2004-06-01 The University Of Chicago Method to produce succinic acid from raw hydrolysates
JP3754014B2 (ja) 2001-09-26 2006-03-08 株式会社東芝 共重合体樹脂組成物およびその製造方法
US7026379B2 (en) 2001-09-26 2006-04-11 Kabushiki Kaisha Toshiba Copolymer resin composition and production process thereof
DE10154175A1 (de) 2001-11-05 2003-05-15 Basf Ag Gene die für Homeostase-und Adaptions-Proteine codieren
JP2003199522A (ja) 2002-01-09 2003-07-15 Inobakkusu Kk 食用調味料
JP4032765B2 (ja) * 2002-02-13 2008-01-16 三菱化学株式会社 有機酸の製造方法
JP2003235592A (ja) * 2002-02-13 2003-08-26 Mitsubishi Chemicals Corp 有機酸の製造方法
JP4469568B2 (ja) 2003-07-09 2010-05-26 三菱化学株式会社 有機酸の製造方法
US7368268B2 (en) 2003-07-29 2008-05-06 Research Institute Of Innovative Technology For The Earth Coryneform bacterium transformant and process for producing dicarboxylic acids using the same
CN100575496C (zh) 2003-08-28 2009-12-30 三菱化学株式会社 产生琥珀酸的方法
JP4575086B2 (ja) 2003-08-28 2010-11-04 三菱化学株式会社 コハク酸の製造方法
WO2005026349A1 (ja) 2003-09-17 2005-03-24 Mitsubishi Chemical Corporation 非アミノ有機酸の製造方法
BRPI0414764B8 (pt) 2003-09-30 2018-09-18 Ajinomoto Kk método para purificar ácido succínico à partir de caldo de fermentação
WO2005113744A1 (ja) 2004-05-20 2005-12-01 Ajinomoto Co., Inc. コハク酸生産菌及びコハク酸の製造方法
JP5572279B2 (ja) 2004-05-20 2014-08-13 味の素株式会社 コハク酸生産菌及びコハク酸の製造方法
US7262046B2 (en) 2004-08-09 2007-08-28 Rice University Aerobic succinate production in bacteria
JP4771437B2 (ja) 2004-08-27 2011-09-14 ライス ユニバーシティー 増加したコハク酸産生を有する変異Ｅ．ｃｏｌｉ株
WO2006069174A2 (en) 2004-12-22 2006-06-29 Rice University Simultaneous anaerobic production of isoamyl acetate and succinic acid
JP2006238843A (ja) 2005-03-07 2006-09-14 Mitsubishi Heavy Ind Ltd コハク酸の製造方法、コハク酸、生分解性プラスチックの製造方法および生分解性プラスチック
JP4760121B2 (ja) 2005-05-17 2011-08-31 三菱化学株式会社 コハク酸の製造方法
WO2007046389A1 (ja) 2005-10-18 2007-04-26 Ajinomoto Co., Inc. コハク酸の製造方法
US7993888B2 (en) 2006-02-24 2011-08-09 Mitsubishi Chemical Corporation Bacterium having enhanced 2-oxoglutarate dehydrogenase activity

Also Published As

Publication number Publication date
US20060205048A1 (en) 2006-09-14
US7763447B2 (en) 2010-07-27
EP1672077A1 (en) 2006-06-21
EP1672077A4 (en) 2011-10-12
CN1875108A (zh) 2006-12-06
CN100575496C (zh) 2009-12-30
EP1672077B1 (en) 2015-01-21
WO2005021770A1 (ja) 2005-03-10

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