BR9510422A - Formulação em pó para administração de polipeptídeos medicamente úteis uso do pó e processos para fabricação da formulação e para tratamento de um paciente carente de terapia - Google Patents

Formulação em pó para administração de polipeptídeos medicamente úteis uso do pó e processos para fabricação da formulação e para tratamento de um paciente carente de terapia

Info

Publication number: BR9510422A
Authority: BR; Brazil
Prior art keywords: formulation; powder; therapy; administration; patient
Prior art date: 1994-12-22

Application number

BR9510422A

Other languages

English (en)

Inventor

Helena Linden

Ann Johansson

Kjell Backstrom

Original Assignee

Astra Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-12-22

Filing date

1995-12-19

Publication date

1998-07-07

1995-12-19 Application filed by Astra Ab filed Critical Astra Ab

1998-07-07 Publication of BR9510422A publication Critical patent/BR9510422A/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pulmonology (AREA)
Diabetes (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Otolaryngology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Endocrinology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Zoology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Toxicology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Peptides Or Proteins (AREA)

BR9510422A 1994-12-22 1995-12-19 Formulação em pó para administração de polipeptídeos medicamente úteis uso do pó e processos para fabricação da formulação e para tratamento de um paciente carente de terapia BR9510422A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9404468A SE9404468D0 (sv)	1994-12-22	1994-12-22	Powder formulations
PCT/SE1995/001541 WO1996019207A1 (en)	1994-12-22	1995-12-19	Powder formulations containing melezitose as a diluent

Publications (1)

Publication Number	Publication Date
BR9510422A true BR9510422A (pt)	1998-07-07

Family

ID=20396435

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9510422A BR9510422A (pt)	1994-12-22	1995-12-19	Formulação em pó para administração de polipeptídeos medicamente úteis uso do pó e processos para fabricação da formulação e para tratamento de um paciente carente de terapia

Country Status (34)

Country	Link
US (1)	US6004574A (pt)
EP (2)	EP1224929B1 (pt)
JP (1)	JPH10510828A (pt)
KR (1)	KR100391873B1 (pt)
CN (1)	CN1080114C (pt)
AR (1)	AR002261A1 (pt)
AT (2)	ATE220900T1 (pt)
AU (1)	AU702898B2 (pt)
BR (1)	BR9510422A (pt)
CA (1)	CA2206803A1 (pt)
CZ (1)	CZ288487B6 (pt)
DE (2)	DE69533294T2 (pt)
DK (2)	DK0799030T3 (pt)
EE (1)	EE03381B1 (pt)
ES (2)	ES2222306T3 (pt)
FI (1)	FI972654A0 (pt)
HK (1)	HK1003619A1 (pt)
HU (1)	HU217975B (pt)
IL (1)	IL116459A (pt)
IS (1)	IS1848B (pt)
MY (1)	MY114211A (pt)
NO (1)	NO315966B1 (pt)
NZ (1)	NZ298168A (pt)
PL (1)	PL183944B1 (pt)
PT (2)	PT799030E (pt)
RU (1)	RU2144819C1 (pt)
SA (1)	SA95160484B1 (pt)
SE (1)	SE9404468D0 (pt)
SK (1)	SK283147B6 (pt)
TR (1)	TR199501632A1 (pt)
TW (1)	TW474823B (pt)
UA (1)	UA44757C2 (pt)
WO (1)	WO1996019207A1 (pt)
ZA (1)	ZA9510753B (pt)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5830853A (en)	1994-06-23	1998-11-03	Astra Aktiebolag	Systemic administration of a therapeutic preparation
US6632456B1 (en) *	1993-06-24	2003-10-14	Astrazeneca Ab	Compositions for inhalation
US6794357B1 (en) *	1993-06-24	2004-09-21	Astrazeneca Ab	Compositions for inhalation
TW402506B (en) *	1993-06-24	2000-08-21	Astra Ab	Therapeutic preparation for inhalation
US6524557B1 (en) *	1994-12-22	2003-02-25	Astrazeneca Ab	Aerosol formulations of peptides and proteins
EE9700138A (et)	1994-12-22	1997-12-15	Astra Aktiebolag	Aerosoolravimvormid
US5898028A (en) *	1997-03-20	1999-04-27	Novo Nordisk A/S	Method for producing powder formulation comprising an insulin
US6043214A (en) *	1997-03-20	2000-03-28	Novo Nordisk A/S	Method for producing powder formulation comprising an insulin
JP2001518916A (ja) *	1997-03-20	2001-10-16	ノボノルディスクアクティーゼルスカブ	結晶インスリンを含有する肺投与のための治療用粉末調合物
AU779869B2 (en) *	1999-04-13	2005-02-17	Nektar Therapeutics	Pulmonary administration of dry powder formulations for treating infertility
WO2000061178A1 (en) *	1999-04-13	2000-10-19	Inhale Therapeutics Systems, Inc.	Pulmonary administration of dry powder formulations for treating infertility
US7169889B1 (en)	1999-06-19	2007-01-30	Biocon Limited	Insulin prodrugs hydrolyzable in vivo to yield peglylated insulin
GB0011807D0 (en) *	2000-05-16	2000-07-05	Quadrant Holdings Cambridge	Formulation for inhalation
AU2001281113B2 (en) *	2000-08-07	2006-07-20	Nektar Therapeutics	Inhaleable spray dried 4-helix bundle protein powders having minimized aggregation
US6867183B2 (en)	2001-02-15	2005-03-15	Nobex Corporation	Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
US7060675B2 (en)	2001-02-15	2006-06-13	Nobex Corporation	Methods of treating diabetes mellitus
US6835802B2 (en)	2001-06-04	2004-12-28	Nobex Corporation	Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties
US6858580B2 (en)	2001-06-04	2005-02-22	Nobex Corporation	Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6828305B2 (en)	2001-06-04	2004-12-07	Nobex Corporation	Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6828297B2 (en)	2001-06-04	2004-12-07	Nobex Corporation	Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US7713932B2 (en)	2001-06-04	2010-05-11	Biocon Limited	Calcitonin drug-oligomer conjugates, and uses thereof
US6713452B2 (en)	2001-06-04	2004-03-30	Nobex Corporation	Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US7030082B2 (en) *	2001-09-07	2006-04-18	Nobex Corporation	Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith
US7196059B2 (en)	2001-09-07	2007-03-27	Biocon Limited	Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
US7166571B2 (en)	2001-09-07	2007-01-23	Biocon Limited	Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US7312192B2 (en)	2001-09-07	2007-12-25	Biocon Limited	Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US6913903B2 (en)	2001-09-07	2005-07-05	Nobex Corporation	Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US6770625B2 (en)	2001-09-07	2004-08-03	Nobex Corporation	Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith
KR20050044523A (ko)	2001-11-19	2005-05-12	벡톤 디킨슨 앤드 컴퍼니	입자 형태의 약제학적 조성물
SE0200657D0 (sv) *	2002-03-04	2002-03-04	Astrazeneca Ab	Novel Formulation
US7601688B2 (en)	2002-06-13	2009-10-13	Biocon Limited	Methods of reducing hypoglycemic episodes in the treatment of diabetes mellitus
KR101309770B1 (ko)	2004-07-19	2013-09-30	바이오콘 리미티드	인슐린―올리고머 접합체，제형 및 이들의 용도
US20090047347A1 (en) *	2005-07-29	2009-02-19	Aegis Therapeutics, Inc.	Compositions for Drug Administration
US8268791B2 (en) *	2004-08-25	2012-09-18	Aegis Therapeutics, Llc.	Alkylglycoside compositions for drug administration
US9895444B2 (en)	2004-08-25	2018-02-20	Aegis Therapeutics, Llc	Compositions for drug administration
US20060046962A1 (en)	2004-08-25	2006-03-02	Aegis Therapeutics Llc	Absorption enhancers for drug administration
EP2457580A1 (en) *	2004-08-25	2012-05-30	The UAB Research Foundation	Absorption enhancers for drug administration
US20140162965A1 (en)	2004-08-25	2014-06-12	Aegis Therapeutics, Inc.	Compositions for oral drug administration
US8226949B2 (en)	2006-06-23	2012-07-24	Aegis Therapeutics Llc	Stabilizing alkylglycoside compositions and methods thereof
KR101234540B1 (ko)	2007-10-16	2013-02-19	바이오콘 리미티드	경구 투여가능한 고형 약제학적 조성물 및 그 제조방법
AU2009228093B2 (en)	2008-03-28	2014-08-07	Neurelis, Inc.	Administration of benzodiazepine compositions
CN101618023B (zh) *	2008-06-30	2011-11-30	江苏先声药物研究有限公司	一种制备微粉化蛋白的方法
US8440631B2 (en)	2008-12-22	2013-05-14	Aegis Therapeutics, Llc	Compositions for drug administration
WO2011131720A1 (en)	2010-04-20	2011-10-27	Octapharma Ag	New stabilizing agent for pharmaceutical proteins
EP2720699B1 (en)	2011-06-14	2018-05-16	Hale Biopharma Ventures, Llc	Administration of benzodiazepine
US9480966B2 (en) *	2012-04-30	2016-11-01	General Electric Company	Substrates and methods for collection, stabilization and elution of biomolecules
AU2015235211B2 (en) *	2014-03-25	2020-01-30	Matsutani Chemical Industry Co., Ltd.	Malaria transmission prevention agent having rare sugar as effective component thereof and malarial parasite growth regulating agent
CN106572690A (zh) *	2014-06-30	2017-04-19	泰特及莱尔组分美国公司	用于消耗品的涂层组合物
US10806770B2 (en)	2014-10-31	2020-10-20	Monash University	Powder formulation
CN108473932B (zh)	2015-09-09	2022-07-15	集联健康有限公司	用于样品收集、稳定化和保存的系统、方法和装置
WO2019157099A1 (en)	2018-02-06	2019-08-15	Aegis Therapeutics, Llc	Intranasal epinephrine formulations and methods for the treatment of disease

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE556587A (pt) *	1957-01-31	1957-04-11
GB1144905A (en) *	1965-03-25	1969-03-12	Fisons Pharmaceuticals Ltd	Substituted bis-(2-carboxy-chromonyl-oxy) derivatives and preparation and pharmaceutical compositions thereof
DE2750090A1 (de) *	1976-11-19	1978-06-01	Sandoz Ag	Neue verabreichungsformen fuer organische verbindungen
SE7812207L (sv) *	1977-12-01	1979-06-02	Welsh Nat School Med	Apparat, forfarande och framstellda produkter for anvendning vid administration av antihistaminer
JPS6034925B2 (ja) *	1979-07-31	1985-08-12	帝人株式会社	持続性鼻腔用製剤およびその製造法
JPS59163313A (ja) *	1983-03-09	1984-09-14	Teijin Ltd	経鼻投与用ペプチドホルモン類組成物
DE3326089A1 (de) *	1983-07-20	1985-02-07	Gödecke AG, 1000 Berlin	Zur inhalation bestimmte darreichungsform von calcium-antagonisten
JPS61267528A (ja) *	1984-11-26	1986-11-27	Yamanouchi Pharmaceut Co Ltd	吸収促進剤を含有するカルシトニン経鼻剤
WO1986006959A1 (en) *	1985-05-22	1986-12-04	Liposome Technology, Inc.	Liposome inhalation method and system
IT1204826B (it) *	1986-03-04	1989-03-10	Chiesi Farma Spa	Composizioni farmaceutiche per inalazione
US5179079A (en) *	1986-12-16	1993-01-12	Novo Nordisk A/S	Nasal formulation and intranasal administration therewith
NZ222907A (en) *	1986-12-16	1990-08-28	Novo Industri As	Preparation for intranasal administration containing a phospholipid absorption enhancing system
EP0360340A1 (en) *	1988-09-19	1990-03-28	Akzo N.V.	Composition for nasal administration containing a peptide
JPH02104531A (ja) *	1988-10-14	1990-04-17	Toyo Jozo Co Ltd	経鼻投与用生理活性ペプチド組成物
US5011678A (en) *	1989-02-01	1991-04-30	California Biotechnology Inc.	Composition and method for administration of pharmaceutically active substances
US5176132A (en) *	1989-05-31	1993-01-05	Fisons Plc	Medicament inhalation device and formulation
JP2642486B2 (ja) *	1989-08-04	1997-08-20	田辺製薬株式会社	難溶性薬物の超微粒子化法
JPH05963A (ja) *	1990-04-13	1993-01-08	Toray Ind Inc	ポリペプチド類組成物
GB9010742D0 (en) *	1990-05-14	1990-07-04	Quadrant Bioresources Ltd	Stabilization of biological macromolecular substances
JP3507486B2 (ja) *	1991-03-15	2004-03-15	アムジエン・インコーポレーテツド	顆粒球コロニー刺激因子の肺内投与
CA2127877A1 (en) *	1992-01-21	1993-07-22	Robert M. Platz	Improved process for preparing micronized polypeptide drugs
WO1994007514A1 (en) *	1992-09-29	1994-04-14	Inhale Therapeutic Systems	Pulmonary delivery of active fragments of parathyroid hormone
IS1796B (is) *	1993-06-24	2001-12-31	Ab Astra	Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband
TW402506B (en) *	1993-06-24	2000-08-21	Astra Ab	Therapeutic preparation for inhalation
US5506203C1 (en) *	1993-06-24	2001-02-06	Astra Ab	Systemic administration of a therapeutic preparation

1994
- 1994-12-22 SE SE9404468A patent/SE9404468D0/xx unknown
1995
- 1995-12-18 ZA ZA9510753A patent/ZA9510753B/xx unknown
- 1995-12-19 TW TW084113557A patent/TW474823B/zh not_active IP Right Cessation
- 1995-12-19 AU AU43592/96A patent/AU702898B2/en not_active Ceased
- 1995-12-19 AT AT95942342T patent/ATE220900T1/de not_active IP Right Cessation
- 1995-12-19 BR BR9510422A patent/BR9510422A/pt not_active Application Discontinuation
- 1995-12-19 US US08/617,753 patent/US6004574A/en not_active Expired - Fee Related
- 1995-12-19 PT PT95942342T patent/PT799030E/pt unknown
- 1995-12-19 ES ES01130870T patent/ES2222306T3/es not_active Expired - Lifetime
- 1995-12-19 SK SK812-97A patent/SK283147B6/sk unknown
- 1995-12-19 AT AT01130870T patent/ATE271382T1/de not_active IP Right Cessation
- 1995-12-19 DE DE69533294T patent/DE69533294T2/de not_active Expired - Fee Related
- 1995-12-19 RU RU97112496A patent/RU2144819C1/ru not_active IP Right Cessation
- 1995-12-19 HU HU9800493A patent/HU217975B/hu not_active IP Right Cessation
- 1995-12-19 EP EP01130870A patent/EP1224929B1/en not_active Expired - Lifetime
- 1995-12-19 DK DK95942342T patent/DK0799030T3/da active
- 1995-12-19 MY MYPI95003942A patent/MY114211A/en unknown
- 1995-12-19 DK DK01130870T patent/DK1224929T3/da active
- 1995-12-19 NZ NZ298168A patent/NZ298168A/en unknown
- 1995-12-19 PT PT01130870T patent/PT1224929E/pt unknown
- 1995-12-19 CA CA002206803A patent/CA2206803A1/en not_active Abandoned
- 1995-12-19 IL IL11645995A patent/IL116459A/en not_active IP Right Cessation
- 1995-12-19 DE DE69527542T patent/DE69527542T2/de not_active Expired - Fee Related
- 1995-12-19 KR KR1019970704254A patent/KR100391873B1/ko not_active Expired - Fee Related
- 1995-12-19 JP JP8519731A patent/JPH10510828A/ja active Pending
- 1995-12-19 PL PL95320751A patent/PL183944B1/pl not_active IP Right Cessation
- 1995-12-19 UA UA97073876A patent/UA44757C2/uk unknown
- 1995-12-19 ES ES95942342T patent/ES2177674T3/es not_active Expired - Lifetime
- 1995-12-19 EE EE9700135A patent/EE03381B1/xx not_active IP Right Cessation
- 1995-12-19 CN CN95196965A patent/CN1080114C/zh not_active Expired - Fee Related
- 1995-12-19 CZ CZ19971946A patent/CZ288487B6/cs not_active IP Right Cessation
- 1995-12-19 EP EP95942342A patent/EP0799030B1/en not_active Expired - Lifetime
- 1995-12-19 WO PCT/SE1995/001541 patent/WO1996019207A1/en active IP Right Grant
- 1995-12-21 AR ARP950100706A patent/AR002261A1/es active IP Right Grant
- 1995-12-21 TR TR95/01632A patent/TR199501632A1/xx unknown
- 1995-12-30 SA SA95160484A patent/SA95160484B1/ar unknown
1997
- 1997-06-03 IS IS4495A patent/IS1848B/is unknown
- 1997-06-10 NO NO19972660A patent/NO315966B1/no unknown
- 1997-06-19 FI FI972654A patent/FI972654A0/fi unknown
1998
- 1998-04-02 HK HK98102788A patent/HK1003619A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE69533294T2 (de)	2005-05-19
CN1080114C (zh)	2002-03-06
EP1224929A2 (en)	2002-07-24
SK81297A3 (en)	1997-11-05
UA44757C2 (uk)	2002-03-15
IS1848B (is)	2003-02-07
NO972660L (no)	1997-06-10
US6004574A (en)	1999-12-21
PT1224929E (pt)	2004-10-29
ES2177674T3 (es)	2002-12-16
IS4495A (is)	1997-06-03
TW474823B (en)	2002-02-01
NO315966B1 (no)	2003-11-24
HU217975B (hu)	2000-05-28
EP0799030B1 (en)	2002-07-24
ATE271382T1 (de)	2004-08-15
DK1224929T3 (da)	2004-10-04
CN1171049A (zh)	1998-01-21
RU2144819C1 (ru)	2000-01-27
MY114211A (en)	2002-08-30
TR199501632A1 (tr)	1997-03-21
HK1003619A1 (en)	1998-11-06
DK0799030T3 (da)	2002-09-16
PT799030E (pt)	2002-11-29
NZ298168A (en)	1999-08-30
EP0799030A1 (en)	1997-10-08
EE9700135A (et)	1997-12-15
SK283147B6 (sk)	2003-03-04
WO1996019207A1 (en)	1996-06-27
IL116459A (en)	2002-11-10
AR002261A1 (es)	1998-03-11
PL320751A1 (en)	1997-10-27
DE69527542D1 (de)	2002-08-29
AU4359296A (en)	1996-07-10
CZ288487B6 (en)	2001-06-13
NO972660D0 (no)	1997-06-10
FI972654L (fi)	1997-06-19
JPH10510828A (ja)	1998-10-20
CZ194697A3 (en)	1997-10-15
EP1224929B1 (en)	2004-07-21
IL116459A0 (en)	1996-03-31
CA2206803A1 (en)	1996-06-27
SA95160484B1 (ar)	2005-10-01
ES2222306T3 (es)	2005-02-01
DE69533294D1 (de)	2004-08-26
KR100391873B1 (ko)	2003-10-17
ZA9510753B (en)	1996-06-24
AU702898B2 (en)	1999-03-11
PL183944B1 (pl)	2002-08-30
FI972654A0 (fi)	1997-06-19
SE9404468D0 (sv)	1994-12-22
HUT77648A (hu)	1998-07-28
ATE220900T1 (de)	2002-08-15
DE69527542T2 (de)	2003-01-30
EE03381B1 (et)	2001-04-16
EP1224929A3 (en)	2002-12-18
MX9704551A (es)	1997-10-31

Publication	Publication Date	Title
BR9510422A (pt)	1998-07-07	Formulação em pó para administração de polipeptídeos medicamente úteis uso do pó e processos para fabricação da formulação e para tratamento de um paciente carente de terapia
BR9510501A (pt)	1998-01-13	Formulação em aerossol uso da mesma e processos para fabricação da mesma e para tratamento de um paciente carente de terapia
BR9510510A (pt)	1998-07-07	Formulação em aerossol farmacêutica uso da mesma e processos para fabricação da mesma para tratamento de um paciente carente de terapia
BR9006924A (pt)	1991-12-10	Formulacao para tratamento de sintomas e doencas,uso de formulacao para o tratamento de sintomas e doencas,metodo para o tratamento de sintomas e doencas,distribuicao de agentes medicinais e terapeuticos para o tratamento de sintomas e doencas e combinacao para administracao em mamiferos
BR9510512A (pt)	1998-07-07	Pó de prolipossoma composição farmacêutica processos para fabricação de um pó de prolipossoma e para tratamento de um paciente que necessita de terapia uso de um pó de prolipossoma e dispositivo inalador de pó seco
EE04021B1 (et)	2003-04-15	7a-( -aminoalküül)östratrieenid, nende valmistamise meetod, 7a-( -aminoalküül)östratrieene sisaldavad farmatseutilised preparaadid ja nende kasutamine ravimite valmistamiseks
BR9610248A (pt)	1999-07-06	Composto composição farmacêutica processos para o tratamento da dor e para a preparação de um composto e uso do composto
CY2007001I1 (el)	2009-11-04	Φαρμακευτικο σκευασμα για χρηση στη θεραπεια του διαβητη
EE9700060A (et)	1997-10-15	2-arüül-asendatud püridiinid,nende valmistamismeetod, kasutamine ravimite valmistamiseks ja nimetatud ühendeid sisaldavad ravimid
IL113844A (en)	2005-05-17	N-(alpha-ETHYLBENZYL)-3-HYDROXY-2-PHENYLQUINOLINE-4-CARBOXAMIDE AND ITS USE IN THE PREPARATION OF MEDICAMENTS
BR9510302A (pt)	1997-11-11	Forma de dosagem farmacêutical de liberação controlada método para tratamento sintomático da tosse método para preparar uma forma de dosagem farmacêutica de liberação controlada composição para uso no tratamento sintomático da tosse e aplicação de uma forma dosagem de moguisteina de liberação controlada
DE69600065D1 (de)	1997-10-23	Dermatologische und/oder pharmazeutische Zubereitung, ihre Herstellung und Anwendung
BR9510516A (pt)	1998-07-07	Preparação terapêutica uso da mesma dispositivo de inalação de pó seco processo de produção da preparação terapêutica e de tratamento de osteoporose
IL130784A0 (en)	2001-01-28	Use of an anti-cd40l compound in the manufacture of a medicament for treating a patient with immune complex disease and pharmaceutical compositions containing the same
FI944600A0 (fi)	1994-10-03	Imidatsol-4-yylipiperidiinijohdannaisia, niiden valmistus ja niiden käyttö terapiassa
FI971188L (fi)	1997-05-20	Terapeuttinen vitamiini-kalsium yhdistelmä yksikköannoksena galeenisen tabletin muodossa, menetelmä sen valmistamiseksi ja sen käyttö
NO307930B1 (no)	2000-06-19	Benzo[f]kinolinoner, farmasøytisk formulering omfattende samme og anvendelse av samme for fremstilling av formulering for behandling
HU904007D0 (en)	1990-12-28	Medical preparations providing regulated active agent discharge and processes for the preparation thereof
BR9611234A (pt)	1999-07-13	Composto formulação farmacêutica uso do composto e processos para tratamento de uma dor e para a preparação de compostos
BR9607169A (pt)	1997-11-11	Uso de meletonina e formulação farmacêutica para uso no tratamento de um viciado em drogas múltiplas
DE59505714D1 (de)	1999-05-27	Kosmetische und/oder pharmazeutische zubereitungen
FI940186A (fi)	1994-07-16	9H-imidatso/1,2-a/bentsimidatsoli-3-asetamidijohdannaisia, niiden valmistus ja niiden käyttö terapiassa
IL164513A0 (en)	2005-12-18	Pyrazolopyrimidines, pharmaceutical compositions containing them, and their use in the preparation of medicaments
FI956353L (fi)	1995-12-29	Farmaseuttiset valmisteet ja niiden käyttö etenkin neurodegeneratiivisten sairauksien hoidossa
IL91451A0 (en)	1990-04-29	Pharmaceutical compositions comprising azapiron compounds and their use in the treatment of addiction

Legal Events

Date	Code	Title
2003-05-27	EG	Technical examination (opinion): publication of technical examination (opinion)
2003-09-09	HJEG	Technical examination (opinion): technical examination (opinion) related to article 229 of industrial property law
2005-04-26	B07B	Technical examination (opinion): publication cancelled [chapter 7.2 patent gazette]
2005-07-26	B09B	Patent application refused [chapter 9.2 patent gazette]