[go: up one dir, main page]

BR8605043A - Efetuacao de alteracoes somaticas em plantas atraves do uso de rna de linhagens negativas - Google Patents

Efetuacao de alteracoes somaticas em plantas atraves do uso de rna de linhagens negativas

Info

Publication number
BR8605043A
BR8605043A BR8605043A BR8605043A BR8605043A BR 8605043 A BR8605043 A BR 8605043A BR 8605043 A BR8605043 A BR 8605043A BR 8605043 A BR8605043 A BR 8605043A BR 8605043 A BR8605043 A BR 8605043A
Authority
BR
Brazil
Prior art keywords
rna
plants
effectiveness
somatic changes
negative
Prior art date
Application number
BR8605043A
Other languages
English (en)
Inventor
Francis P Mccormick
Kenneth A Barton
William F Swain
Original Assignee
Agracetus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25143142&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR8605043(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Agracetus filed Critical Agracetus
Publication of BR8605043A publication Critical patent/BR8605043A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y105/00Oxidoreductases acting on the CH-NH group of donors (1.5)
    • C12Y105/01Oxidoreductases acting on the CH-NH group of donors (1.5) with NAD+ or NADP+ as acceptor (1.5.1)
    • C12Y105/01019D-Nopaline dehydrogenase (1.5.1.19), i.e. D-nopaline synthase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/11Antisense
    • C12N2310/111Antisense spanning the whole gene, or a large part of it

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
BR8605043A 1985-10-16 1986-10-15 Efetuacao de alteracoes somaticas em plantas atraves do uso de rna de linhagens negativas BR8605043A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/788,002 US6617496B1 (en) 1985-10-16 1985-10-16 Effecting virus resistance in plants through the use of negative strand RNAs

Publications (1)

Publication Number Publication Date
BR8605043A true BR8605043A (pt) 1987-07-14

Family

ID=25143142

Family Applications (1)

Application Number Title Priority Date Filing Date
BR8605043A BR8605043A (pt) 1985-10-16 1986-10-15 Efetuacao de alteracoes somaticas em plantas atraves do uso de rna de linhagens negativas

Country Status (7)

Country Link
US (1) US6617496B1 (pt)
EP (1) EP0223399B1 (pt)
AT (1) ATE104699T1 (pt)
AU (1) AU607122B2 (pt)
BR (1) BR8605043A (pt)
CA (1) CA1341556C (pt)
DE (1) DE3689802T2 (pt)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751181A (en) * 1984-12-31 1988-06-14 Duke University Methods and compositions useful in the diagnosis and treatment of autoimmune diseases
EP1213348A2 (en) * 1985-03-21 2002-06-12 Johnston, Stephen, Ph.D. Parasite-derived resistance
US6608241B1 (en) 1985-10-29 2003-08-19 Monsanto Technology Llc Protection of plants against viral infection
US5453566A (en) * 1986-03-28 1995-09-26 Calgene, Inc. Antisense regulation of gene expression in plant/cells
IL81737A (en) * 1986-03-28 1992-11-15 Calgene Inc Regulation of gene expression in plant cells
US5107065A (en) * 1986-03-28 1992-04-21 Calgene, Inc. Anti-sense regulation of gene expression in plant cells
DE3751393T2 (de) * 1986-04-02 1996-02-22 Pioneer Hi Bred Int Pflanzen, resistent gegen den Anti-sens RNS aufweisenden Virus.
EP0323473A4 (en) * 1986-08-26 1990-02-21 Univ Macquarie Transformation of an organism using antisense rna or promoter occlusion technique.
US5356799A (en) 1988-02-03 1994-10-18 Pioneer Hi-Bred International, Inc. Antisense gene systems of pollination control for hybrid seed production
US6255564B1 (en) 1988-02-03 2001-07-03 Paladin Hybrids, Inc. Molecular methods of hybrid seed production
US6737560B1 (en) 1988-02-03 2004-05-18 Pioneer Hi-Bred International, Inc. Molecular methods of hybrid seed production
US5728926A (en) * 1988-02-03 1998-03-17 Pioneer Hi-Bred International, Inc. Antisense gene systems of pollination control for hybrid seed production
NL8800756A (nl) * 1988-03-25 1989-10-16 Vereniging Voor Christelijk Wetenschappelijk Onderwijs Genetisch gemanipuleerde plantecellen en planten, alsmede daarvoor bruikbaar recombinant dna.
DE3810286A1 (de) * 1988-03-25 1989-10-12 Max Planck Gesellschaft Transgene pflanze mit modifizierter physiologie, morphologie und modifiziertem hormonmetabolismus, gewebekulturen dieser pflanze und verfahren zu ihrer herstellung
US5260205A (en) * 1990-11-14 1993-11-09 Philip Morris Incorporated Method of purifying putrescine N-methyltransferase from tobacco plant extract with a polyamine
US6013859A (en) * 1994-07-14 2000-01-11 Pioneer Hi-Bred International, Inc. Molecular methods of hybrid seed production
US6586661B1 (en) 1997-06-12 2003-07-01 North Carolina State University Regulation of quinolate phosphoribosyl transferase expression by transformation with a tobacco quinolate phosphoribosyl transferase nucleic acid
CN101818145A (zh) 1998-03-20 2010-09-01 联邦科学和工业研究组织 控制基因表达
AUPP249298A0 (en) 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
US8598332B1 (en) 1998-04-08 2013-12-03 Bayer Cropscience N.V. Methods and means for obtaining modified phenotypes
US20040214330A1 (en) 1999-04-07 2004-10-28 Waterhouse Peter Michael Methods and means for obtaining modified phenotypes
EP1068311B2 (en) 1998-04-08 2020-12-09 Commonwealth Scientific and Industrial Research Organisation Methods and means for obtaining modified phenotypes
US6759574B1 (en) 1998-11-05 2004-07-06 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Plants having enhanced gall resistance and methods and compositions for producing same
DK1131450T3 (da) 1998-11-12 2012-05-14 Max Planck Gesellschaft Kimære promotorer, der kan formidle genekspression i planter ved patogeninfektion, og anvendelser heraf
ATE305718T1 (de) 1999-07-20 2005-10-15 Gvs Ges Fuer Erwerb Und Verwer Neues verfahren zur herstellung und auswahl von transgenen flachspflanzen und leinsamen
US6423885B1 (en) 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
US7192771B2 (en) 2000-08-30 2007-03-20 North Carolina State University Plant promoter sequence
EP1368467B1 (en) 2000-11-07 2007-04-25 North Carolina State University Putrescine-n-methyltransferase promoter
AU1480402A (en) 2000-11-09 2002-05-21 Commw Scient Ind Res Org Barley with reduced SSII activity and starch containing products with a reduced amylopectin content
NZ530238A (en) 2001-06-08 2004-08-27 Vector Tobacco Ltd Modifying nicotine and nitrosamine levels in tobacco
WO2003076619A1 (en) 2002-03-14 2003-09-18 Commonwealth Scientific And Industrial Research Organisation Modified gene-silencing rna and uses thereof
CN1771327B (zh) 2003-04-11 2010-04-28 作物培植股份有限公司 逆境耐受性
US7812221B2 (en) 2003-06-30 2010-10-12 Commonwealth Scientific And Industrial Research Organization Wheat with altered branching enzyme activity and starch and starch containing products derived therefrom
EP2868749B1 (en) 2004-01-20 2017-10-04 Monsanto Technology LLC Chimeric promoters for use in plants
US7453025B2 (en) 2004-09-22 2008-11-18 Arborgen, Llc Reproductive ablation constructs
WO2006069422A1 (en) 2004-12-30 2006-07-06 Commonwealth Scientific And Industrial Research Organisation Method and means for improving bowel health
RU2458133C2 (ru) 2005-09-20 2012-08-10 Дж.Р. Симплот Компани Пищевые продукты с низким содержанием акриламида
US7838729B2 (en) 2007-02-26 2010-11-23 Monsanto Technology Llc Chloroplast transit peptides for efficient targeting of DMO and uses thereof
US20090123626A1 (en) * 2007-09-28 2009-05-14 J.R. Simplot Company Reduced acrylamide plants and foods
EP2222859A2 (en) 2007-12-21 2010-09-01 Keygene N.V. Trichome specific promoters
EP2100962A1 (en) 2008-03-12 2009-09-16 Biogemma Plants having improved resistance to pathogens
ES2457218T3 (es) 2008-04-07 2014-04-25 Monsanto Technology Llc Elementos reguladores de plantas y usos de los mismos
US20120277117A1 (en) 2009-02-27 2012-11-01 Adel Zayed Hydroponic apparatus and methods of use
CN102459615B (zh) 2009-06-08 2017-05-03 纽海姆有限公司 耐旱植物
US8937214B2 (en) 2009-10-23 2015-01-20 Monsanto Technology Llc Methods and compositions for expression of transgenes in plants
ES2736037T3 (es) 2010-01-14 2019-12-23 Monsanto Technology Llc Elementos reguladores de las plantas y usos de los mismos
CN107974457A (zh) 2010-05-28 2018-05-01 纽海姆有限公司 果实大小增大的植物
ES2657233T3 (es) 2010-08-30 2018-03-02 Dow Agrosciences, Llc Potenciador viral baciliforme de la caña de azúcar (SCBV) y su uso en la genómica vegetal funcional
US8648230B2 (en) 2011-03-18 2014-02-11 Ms Technologies, Llc Regulatory regions preferentially expressing in non-pollen plant tissue
RU2644205C2 (ru) 2011-03-25 2018-02-08 Монсанто Текнолоджи Ллс Регуляторные элементы растений и их применение
EA031839B1 (ru) 2011-05-13 2019-02-28 Монсанто Текнолоджи Ллс Регуляторные элементы растений и их применение
CN104411827B (zh) 2012-02-29 2018-01-02 陶氏益农公司 甘蔗杆状病毒(scbv)增强子及其在植物功能基因组学中的用途
WO2013134651A1 (en) 2012-03-09 2013-09-12 Board Of Trustees Of Michigan State University Method of enhancing plant drought tolerance by expression of ndr1
US9663793B2 (en) 2012-04-20 2017-05-30 Monsanto Technology, Llc Plant regulatory elements and uses thereof
EP3434771B1 (en) 2012-12-19 2023-09-13 Monsanto Technology LLC Plant regulatory elements and uses thereof
WO2014159434A1 (en) 2013-03-14 2014-10-02 Monsanto Technology Llc Plant regulatory elements and uses thereof
MX352666B (es) 2013-03-14 2017-12-01 Monsanto Technology Llc Elementos reguladores de plantas y sus usos.
EP3274462A4 (en) 2015-03-26 2018-12-26 The Texas A&M University System Conversion of lignin into bioplastics and lipid fuels
AU2016318051B2 (en) 2015-09-04 2022-11-03 Keygene N.V. Diplospory gene
CN115125253A (zh) 2016-03-11 2022-09-30 孟山都技术公司 植物调控元件及其用途
CR20180607A (es) 2016-05-24 2019-03-26 Monsanto Technology Llc Elementos reguladores de plantas y sus usos
WO2018005589A1 (en) 2016-06-28 2018-01-04 Cellectis Altering expression of gene products in plants through targeted insertion of nucleic acid sequences
ES2986585T3 (es) 2017-01-19 2024-11-12 Monsanto Technology Llc Elementos reguladores de plantas y sus usos
WO2019139616A1 (en) 2018-01-12 2019-07-18 The Texas A&M University System Increasing plant bioproduct yield
AR125216A1 (es) 2021-03-26 2023-06-28 Flagship Pioneering Innovations Vii Llc Producción de polirribonucleótidos circulares en un sistema eucariota
TW202305130A (zh) 2021-03-26 2023-02-01 美商旗艦先鋒創新有限責任(Vii)公司 原核系統中環狀多核糖核苷酸之產生
TW202300650A (zh) 2021-03-26 2023-01-01 美商旗艦先鋒創新有限責任(Vii)公司 真核系統中環狀多核糖核苷酸的產生
WO2023077118A1 (en) 2021-11-01 2023-05-04 Flagship Pioneering Innovations Vii, Llc Polynucleotides for modifying organisms
AU2023209447A1 (en) 2022-01-20 2024-07-18 Flagship Pioneering Innovations Vii, Llc Polynucleotides for modifying organisms
AU2023337091A1 (en) 2022-09-09 2025-03-06 Eidgenössische Technische Hochschule Zürich Plant regulatory elements and uses thereof
WO2024229347A1 (en) 2023-05-03 2024-11-07 Flagship Pioneering Innovations Vii, Llc Artificial tombusviridae satellite rnas
WO2024229395A1 (en) 2023-05-03 2024-11-07 Flagship Pioneering Innovations Vii, Llc Partitiviral satellite rna amplification systems for plants
WO2024229403A1 (en) 2023-05-03 2024-11-07 Flagship Pioneering Innovations Vii, Llc Endornaviral satellite rna amplification systems for plants
WO2024229385A1 (en) 2023-05-03 2024-11-07 Flagship Pioneering Innovations Vii, Llc Artificial ghabrivirales satellite rnas
WO2024229362A1 (en) 2023-05-03 2024-11-07 Flagship Pioneering Innovations Vii, Llc ARTIFICIAL MARTELLIVIRALES SATELLITE RNAs
WO2024229398A1 (en) 2023-05-03 2024-11-07 Flagship Pioneering Innovations Vii, Llc Artificial amalgavirus satellite rnas
WO2024229351A1 (en) 2023-05-03 2024-11-07 Flagship Pioneering Innovations Vii, Llc Artificial secoviridae satellite rnas
WO2024229359A2 (en) 2023-05-03 2024-11-07 Flagship Pioneering Innovations Vii, Llc Artificial tymovirales satellite rnas
WO2024229356A2 (en) 2023-05-03 2024-11-07 Flagship Pioneering Innovations Vii, Llc Artificial solemoviridae satellite rnas
US20250075226A1 (en) 2023-08-29 2025-03-06 University Of Freiburg Proteins for regulation of symbiotic infection and associated regulatory elements

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0126546B2 (en) * 1983-04-15 1994-03-30 Lubrizol Genetics Inc. Plant structural gene expression
EP0140308B2 (en) 1983-10-20 2001-10-17 The Research Foundation Of State University Of New York Regulation of gene expression by employing translational inhibition utilizing mRNA interfering complementary RNA
US5580716A (en) * 1985-03-21 1996-12-03 Stephen A. Johnston Parasite-derived resistance
IL81737A (en) * 1986-03-28 1992-11-15 Calgene Inc Regulation of gene expression in plant cells
ATE123528T1 (de) * 1986-07-25 1995-06-15 Univ Louisiana State Verfahren zum verleihen bei pflanzen eines widerstands gegen krankheiten und pest sowie neue gene in pflanzen die hierfür kodieren.
AU7918387A (en) * 1986-08-26 1988-03-24 Macquarie University Transformation of an organism using antisense rna or promoter occlusion technique

Also Published As

Publication number Publication date
DE3689802D1 (de) 1994-05-26
AU6392486A (en) 1987-04-30
ATE104699T1 (de) 1994-05-15
EP0223399B1 (en) 1994-04-20
DE3689802T2 (de) 1994-11-17
US6617496B1 (en) 2003-09-09
CA1341556C (en) 2007-10-09
EP0223399A1 (en) 1987-05-27
AU607122B2 (en) 1991-02-28

Similar Documents

Publication Publication Date Title
BR8605043A (pt) Efetuacao de alteracoes somaticas em plantas atraves do uso de rna de linhagens negativas
CY1108712T1 (el) Μεθοδος για την παραγωγη ανθεκτικων φυτων σε διαφορες μορφες στρες
OA06809A (fr) Dérivés 1-hydroxyéthyl-azoliques, leur procédé de production ainsi que leur utilisation comme substances de croissance des plantes et comme fongicides.
EP0227264A3 (en) Transformation and foreign gene expression with woody species
ES2168510T3 (es) Transformacion de plantas de algodon.
ATE213019T1 (de) Chimäre oligomere mit einer rns- spaltungsaktivität
FI880383A0 (fi) Transformation och expression av en fraemmande gen i brassicaarter.
ES2195993T3 (es) Metodo para inhibir la produccion de etileno en plantas.
FR2724934B1 (fr) Oligonucleotide chimere et son utilisation dans l'obtention de transcrits d'un acide nucleique
IE870201L (en) "a method for the expression of genes in plants, parts of¹plants, and plant cell cultures, and dna fragments,¹plasmids, and transformed microorganisms to be used when¹carrying out the method, as well as the use thereof for the¹expression of genes in plants parts of plants, and plant¹cell cultures"
ES2180641T3 (es) Inhibicion citoplasmica de la expresion genetica.
SE8801070D0 (sv) Method for immobilizing a dna sequence on a solid support
MX9800500A (es) Inhibicion de la expresion de genes.
GR3017682T3 (en) Virus resistant plants having antisense RNA.
BR8806136A (pt) Metodo para regeneracao de uma planta algodoeira a partir de celulas somaticas
ES2114531T3 (es) Inhibicion de la transformacion de celulas que tienen una actividad enzimatica elevada del metabolismo de purinas.
OA06866A (fr) Dérivés de triazolylpropénol, leur procédé de production et leur utilisation comme substances de croissance des plantes et comme fongicides.
BR9811014A (pt) "região concentrada reguladora de gene especìfica para semente precoce"
ATE443772T1 (de) Verfahren zur unterdrückung der genexpression in pflanzen
BR8502281A (pt) Aplicacao de amidas,processo para aperfeicoar a tolerabilidade de plantas de cultura de heteroariloxiacetamidas de acao herbicida,composicoes e processo para o combate seletivo de ervas daninhas,aplicacao e processo para a preparacao de composicoes
IT7922818A0 (it) Procedimento per mantenere attiva la cultura di fermenti.
ES8302089A1 (es) Procedimiento para la preparacion microbiologica de un polipeplido que contiene total o parcialmente la secuencia de aminoacidos del interferon de fibrobastos humanos.
IT7823506A0 (it) Impianto per fermentazione anaerobica.
BR9305489A (pt) Plantas resistentes contra vírus plural e processo para produzir as mesmas
ES2074105T3 (es) Arn con actividad de endorribonucleasa contra arnm de genes de maduracion, su preparacion y su utilizacion en plantas.

Legal Events

Date Code Title Description
NF Application restored
FD3 Appl. lapsed due to non-payment of renewal fee
NF Application restored
EG Technical examination (opinion): publication of technical examination (opinion)
FB36 Technical and formal requirements: requirement - article 36 of industrial property law
FC Decision: refusal
CKFC Appeal: appeal against refusal