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BR112014021602A2 - uso, kit e derivado de retinal sintético para melhorar a função visual em distúrbios visuais associados com a deficiência de produção endógena de retinóide - Google Patents

uso, kit e derivado de retinal sintético para melhorar a função visual em distúrbios visuais associados com a deficiência de produção endógena de retinóide

Info

Publication number
BR112014021602A2
BR112014021602A2 BR112014021602A BR112014021602A BR112014021602A2 BR 112014021602 A2 BR112014021602 A2 BR 112014021602A2 BR 112014021602 A BR112014021602 A BR 112014021602A BR 112014021602 A BR112014021602 A BR 112014021602A BR 112014021602 A2 BR112014021602 A2 BR 112014021602A2
Authority
BR
Brazil
Prior art keywords
visual
deficiency
disorders associated
kit
synthetic retinal
Prior art date
Application number
BR112014021602A
Other languages
English (en)
Inventor
Cadden Suzanne
Original Assignee
Quadra Logic Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quadra Logic Tech Inc filed Critical Quadra Logic Tech Inc
Publication of BR112014021602A2 publication Critical patent/BR112014021602A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/11—Aldehydes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

uso, kit e derivado de retinal sintético para melhorar a função visual em distúrbios visuais associados com a deficiência de produção endógena de retinóide. são aqui descritos regimes terapêuticos para melhorar a função visual na retinite pigmentosa e outros distúrbios visuais associados com uma deficiência na produção endógena de retinóide em um indivíduo mediante a administração de uma quantidade terapeuticamente eficaz de um derivado de retinal sintético, por exemplo, um éster de 9- ou de 11-cis-retinila, de acordo com o regime terapêutico que leva à recuperação local das funções visuais, tais como do campo visual, acuidade visual e sensibilidade retinal, entre outros.
BR112014021602A 2012-03-01 2013-03-01 uso, kit e derivado de retinal sintético para melhorar a função visual em distúrbios visuais associados com a deficiência de produção endógena de retinóide BR112014021602A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261605729P 2012-03-01 2012-03-01
US201261642212P 2012-05-03 2012-05-03
US201261644360P 2012-05-08 2012-05-08
PCT/CA2013/050155 WO2013134867A1 (en) 2012-03-01 2013-03-01 Therapeutic regimens and methods for improving visual function in visual disorders associated with an endogenous retinoid deficiency

Publications (1)

Publication Number Publication Date
BR112014021602A2 true BR112014021602A2 (pt) 2021-06-08

Family

ID=49160185

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014021602A BR112014021602A2 (pt) 2012-03-01 2013-03-01 uso, kit e derivado de retinal sintético para melhorar a função visual em distúrbios visuais associados com a deficiência de produção endógena de retinóide

Country Status (16)

Country Link
US (2) US20160296478A1 (pt)
EP (1) EP2819667B8 (pt)
JP (3) JP6576636B2 (pt)
KR (1) KR102133608B1 (pt)
CN (2) CN104470511A (pt)
AU (3) AU2013232697B2 (pt)
BR (1) BR112014021602A2 (pt)
CA (1) CA2865935C (pt)
DK (1) DK2819667T3 (pt)
ES (1) ES2780357T3 (pt)
IL (1) IL234306B (pt)
MX (2) MX389866B (pt)
NZ (1) NZ629267A (pt)
PT (1) PT2819667T (pt)
RU (1) RU2635536C2 (pt)
WO (1) WO2013134867A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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CA2796991A1 (en) 2010-04-19 2011-10-27 Qlt Inc. Therapeutic regimen and methods for treating or ameliorating visual disorders associated with an endogenous retinoid deficiency
MX389866B (es) 2012-03-01 2025-03-20 Retinagenix LLC El uso de 9-cis-retinil acetato para mejorar la funcion visual de un sujeto que padece de perdida de la funcion visual originada por una deficiencia retinoide endogena de 11-cis retinal.
WO2015164419A1 (en) * 2014-04-22 2015-10-29 Acucela Inc. Pupillometric assessment of retinal pharmacodynamics and responses therefrom
US12029715B2 (en) * 2015-05-08 2024-07-09 University Of Debrecen Precursor compounds for providing retinoids of the vitamin A5 pathway and uses thereof
US20180170867A1 (en) * 2015-05-08 2018-06-21 University Of Debrecen Stereoselective synthesis of 9-cis.13,14-dihydroretinoic acid and its ethyl esters
WO2018091937A1 (en) 2016-11-17 2018-05-24 University Of Debrecen Precursor compounds for providing retinoids of the vitamin a5 pathway and uses thereof
RU186184U1 (ru) * 2018-06-06 2019-01-11 Федеральное государственное бюджетное учреждение "33 Центральный научно-исследовательский испытательный институт" Министерства обороны Российской Федерации Устройство для оценки углов обзора и поля зрения испытателей в противогазе
AU2021289331A1 (en) * 2020-06-09 2022-12-15 Eluminex Biosciences (Suzhou) Limited Methods of treating visual disorders using daily low dosing of a retinoid compound
WO2024110625A1 (en) 2022-11-24 2024-05-30 Universität Bern Cralbp based therapeutics for retinal disorders

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Also Published As

Publication number Publication date
AU2019283995A1 (en) 2020-01-23
PT2819667T (pt) 2020-03-31
EP2819667B1 (en) 2019-12-25
MX370928B (es) 2020-01-08
US20190054039A1 (en) 2019-02-21
EP2819667A4 (en) 2015-08-05
KR102133608B1 (ko) 2020-07-13
AU2013232697B2 (en) 2017-10-19
CN104470511A (zh) 2015-03-25
DK2819667T3 (da) 2020-03-30
US20160296478A1 (en) 2016-10-13
KR20150000881A (ko) 2015-01-05
AU2018200415A1 (en) 2018-02-08
MX389866B (es) 2025-03-20
JP2020073597A (ja) 2020-05-14
AU2018200415B2 (en) 2019-09-26
JP6576636B2 (ja) 2019-09-18
NZ629267A (en) 2016-11-25
MX2014010457A (es) 2015-04-08
CA2865935A1 (en) 2013-09-19
RU2014139666A (ru) 2016-04-20
CN109248163A (zh) 2019-01-22
JP2017197588A (ja) 2017-11-02
AU2013232697A1 (en) 2014-09-18
WO2013134867A1 (en) 2013-09-19
HK1205469A1 (en) 2015-12-18
IL234306B (en) 2022-02-01
RU2635536C2 (ru) 2017-11-13
AU2019283995B2 (en) 2021-11-11
US10828267B2 (en) 2020-11-10
EP2819667A1 (en) 2015-01-07
EP2819667B8 (en) 2020-03-04
JP2015508783A (ja) 2015-03-23
ES2780357T3 (es) 2020-08-25
CA2865935C (en) 2021-12-14

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