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BG61484B1 - 3'-(2')-амино-и тиолмодифицирани, свързани с флуоресциращо багрило нуклеозиди,нуклеотиди и олигонуклеотиди и метод за тяхното получаване и приложението им - Google Patents

3'-(2')-амино-и тиолмодифицирани, свързани с флуоресциращо багрило нуклеозиди,нуклеотиди и олигонуклеотиди и метод за тяхното получаване и приложението им Download PDF

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Publication number
BG61484B1
BG61484B1 BG95575A BG9557591A BG61484B1 BG 61484 B1 BG61484 B1 BG 61484B1 BG 95575 A BG95575 A BG 95575A BG 9557591 A BG9557591 A BG 9557591A BG 61484 B1 BG61484 B1 BG 61484B1
Authority
BG
Bulgaria
Prior art keywords
group
amino
synthesis
formula
oligonucleotides
Prior art date
Application number
BG95575A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG95575A (bg
Inventor
Joachim Engels
Mathias Herrlein
Renate Konrad
Matthias Mag
Original Assignee
Hoechst Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Aktiengesellschaft filed Critical Hoechst Aktiengesellschaft
Publication of BG95575A publication Critical patent/BG95575A/bg
Publication of BG61484B1 publication Critical patent/BG61484B1/bg

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • C07H19/20Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG95575A 1990-12-11 1991-12-04 3'-(2')-амино-и тиолмодифицирани, свързани с флуоресциращо багрило нуклеозиди,нуклеотиди и олигонуклеотиди и метод за тяхното получаване и приложението им BG61484B1 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4039488 1990-12-11

Publications (2)

Publication Number Publication Date
BG95575A BG95575A (bg) 1993-12-24
BG61484B1 true BG61484B1 (bg) 1997-09-30

Family

ID=6420050

Family Applications (1)

Application Number Title Priority Date Filing Date
BG95575A BG61484B1 (bg) 1990-12-11 1991-12-04 3'-(2')-амино-и тиолмодифицирани, свързани с флуоресциращо багрило нуклеозиди,нуклеотиди и олигонуклеотиди и метод за тяхното получаване и приложението им

Country Status (27)

Country Link
US (3) US5679785A (sh)
EP (1) EP0490281B1 (sh)
JP (1) JP3140127B2 (sh)
KR (1) KR920012107A (sh)
AT (1) ATE142222T1 (sh)
AU (1) AU643856B2 (sh)
BG (1) BG61484B1 (sh)
BR (1) BR9105335A (sh)
CA (1) CA2057475A1 (sh)
CS (1) CS374391A3 (sh)
DE (1) DE59108143D1 (sh)
DK (1) DK0490281T3 (sh)
ES (1) ES2093671T3 (sh)
FI (1) FI915779A (sh)
GR (1) GR3021041T3 (sh)
HU (1) HUT60505A (sh)
IE (1) IE75726B1 (sh)
IL (1) IL100298A (sh)
MX (1) MX9102468A (sh)
NO (1) NO914859L (sh)
NZ (1) NZ240900A (sh)
PL (1) PL168874B1 (sh)
PT (1) PT99747A (sh)
RO (1) RO111575B1 (sh)
RU (1) RU2073682C1 (sh)
TR (1) TR27715A (sh)
YU (1) YU187991A (sh)

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ATE352586T2 (de) * 2000-09-29 2007-02-15 Molecular Probes Inc Modifizierte carbocyaninfarbstoffe und deren konjugate
US7563618B2 (en) 2001-03-23 2009-07-21 Geron Corporation Oligonucleotide conjugates
KR100762261B1 (ko) 2001-04-27 2007-10-04 (주)바이오니아 전장 상보 디옥시리보핵산 제조 방법과 이에 사용되는앵커와 프라이머
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JP4177123B2 (ja) * 2003-01-10 2008-11-05 富士通株式会社 配線図形検証方法、プログラム及び装置
BRPI0408967B8 (pt) 2003-03-31 2021-07-27 Hoffmann La Roche kit e métodos para detecção de um ácido nucléico de vários membros do sorogrupo do vírus da encefalite japonesa em uma amostra biológica sob condições de hibridização rigorosas
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JP2008519108A (ja) * 2004-10-29 2008-06-05 モレキュラー プローブス, インコーポレイテッド 官能化蛍光性ナノ結晶、並びにそれらの調製及び使用方法
US20090118132A1 (en) * 2004-11-04 2009-05-07 Roche Molecular Systems, Inc. Classification of Acute Myeloid Leukemia
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Also Published As

Publication number Publication date
GR3021041T3 (en) 1996-12-31
NZ240900A (en) 1994-07-26
US5679785A (en) 1997-10-21
FI915779A (fi) 1992-06-12
US5668269A (en) 1997-09-16
IE914301A1 (en) 1992-06-17
PT99747A (pt) 1992-11-30
IL100298A0 (en) 1992-09-06
JP3140127B2 (ja) 2001-03-05
YU187991A (sh) 1994-09-09
PL168874B1 (pl) 1996-04-30
AU643856B2 (en) 1993-11-25
EP0490281B1 (de) 1996-09-04
CA2057475A1 (en) 1992-06-12
FI915779A0 (fi) 1991-12-09
PL292701A1 (en) 1992-09-21
AU8892791A (en) 1992-06-18
HUT60505A (en) 1992-09-28
ES2093671T3 (es) 1997-01-01
DE59108143D1 (de) 1996-10-10
TR27715A (tr) 1995-06-22
ATE142222T1 (de) 1996-09-15
RU2073682C1 (ru) 1997-02-20
KR920012107A (ko) 1992-07-25
HU913885D0 (en) 1992-02-28
IE75726B1 (en) 1997-09-24
BG95575A (bg) 1993-12-24
BR9105335A (pt) 1992-08-25
CS374391A3 (en) 1992-06-17
RO111575B1 (ro) 1996-11-29
JPH04290896A (ja) 1992-10-15
IL100298A (en) 1997-03-18
NO914859L (no) 1992-06-12
DK0490281T3 (sh) 1997-02-10
US5659025A (en) 1997-08-19
NO914859D0 (no) 1991-12-10
EP0490281A1 (de) 1992-06-17
MX9102468A (es) 1992-06-01

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