[go: up one dir, main page]

BG107770A - Извлечени от кръв на човешка пъпна връв свободни соматични стволови клетки - Google Patents

Извлечени от кръв на човешка пъпна връв свободни соматични стволови клетки Download PDF

Info

Publication number
BG107770A
BG107770A BG107770A BG10777003A BG107770A BG 107770 A BG107770 A BG 107770A BG 107770 A BG107770 A BG 107770A BG 10777003 A BG10777003 A BG 10777003A BG 107770 A BG107770 A BG 107770A
Authority
BG
Bulgaria
Prior art keywords
cells
stem cells
somatic stem
ussc
cells according
Prior art date
Application number
BG107770A
Other languages
Bulgarian (bg)
English (en)
Inventor
Peter Wernet
Original Assignee
Kourion Therapeutics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kourion Therapeutics Gmbh filed Critical Kourion Therapeutics Gmbh
Publication of BG107770A publication Critical patent/BG107770A/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Developmental Biology & Embryology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Neurosurgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Psychology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
BG107770A 2000-11-03 2003-04-30 Извлечени от кръв на човешка пъпна връв свободни соматични стволови клетки BG107770A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24516800P 2000-11-03 2000-11-03
PCT/EP2001/012768 WO2002036751A2 (en) 2000-11-03 2001-11-03 Human cord blood derived unrestricted somatic stem cells (ussc)

Publications (1)

Publication Number Publication Date
BG107770A true BG107770A (bg) 2004-02-27

Family

ID=22925565

Family Applications (1)

Application Number Title Priority Date Filing Date
BG107770A BG107770A (bg) 2000-11-03 2003-04-30 Извлечени от кръв на човешка пъпна връв свободни соматични стволови клетки

Country Status (25)

Country Link
US (3) US7560280B2 (zh)
EP (1) EP1404815B1 (zh)
JP (2) JP4799804B2 (zh)
CN (1) CN100480375C (zh)
AT (1) ATE340255T1 (zh)
AU (2) AU2953302A (zh)
BG (1) BG107770A (zh)
CA (1) CA2426987C (zh)
CY (1) CY1106287T1 (zh)
CZ (1) CZ20031165A3 (zh)
DE (1) DE60123293T2 (zh)
DK (1) DK1404815T3 (zh)
EA (1) EA008619B1 (zh)
EE (1) EE200300205A (zh)
ES (1) ES2272563T3 (zh)
HK (1) HK1071771A1 (zh)
HU (1) HUP0301600A3 (zh)
IL (2) IL155608A0 (zh)
MX (1) MXPA03003844A (zh)
NO (1) NO20031999L (zh)
PL (1) PL362293A1 (zh)
PT (1) PT1404815E (zh)
SK (1) SK5242003A3 (zh)
UA (1) UA81390C2 (zh)
WO (1) WO2002036751A2 (zh)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2338928A1 (en) * 1998-07-30 2000-02-10 Hynda K. Kleinman Thymosin .beta.4 promotes wound repair
US7927587B2 (en) * 1999-08-05 2011-04-19 Regents Of The University Of Minnesota MAPC administration for the treatment of lysosomal storage disorders
US8075881B2 (en) 1999-08-05 2011-12-13 Regents Of The University Of Minnesota Use of multipotent adult stem cells in treatment of myocardial infarction and congestive heart failure
US10638734B2 (en) 2004-01-05 2020-05-05 Abt Holding Company Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
US8609412B2 (en) * 1999-08-05 2013-12-17 Regents Of The University Of Minnesota Mapc generation of lung tissue
CA2852534A1 (en) * 1999-08-05 2001-02-15 Abt Holding Company Multipotent adult stem cells and methods for isolation
US8252280B1 (en) 1999-08-05 2012-08-28 Regents Of The University Of Minnesota MAPC generation of muscle
US7015037B1 (en) * 1999-08-05 2006-03-21 Regents Of The University Of Minnesota Multiponent adult stem cells and methods for isolation
JP2004529621A (ja) * 2001-02-14 2004-09-30 ティー ファークト，レオ 多能性成体幹細胞、その起源、それを得る方法および維持する方法、それを分化させる方法、その使用法、ならびにそれ由来の細胞
AU2002336408B2 (en) * 2001-08-29 2006-12-21 Regenerx Biopharmaceuticals, Inc. Methods of healing or preventing inflammation, damage and other changes that occur prior to, during or immediately after a myocardial event with thymosin beta 4, analogues, isoforms and other derivatives
DE10144326B4 (de) * 2001-09-10 2005-09-22 Siemens Ag Verfahren und System zur Überwachung eines Reifenluftdrucks
DE10158680B4 (de) * 2001-11-30 2004-04-08 Universitätsklinikum Hamburg-Eppendorf Verfahren zur ex vivo-Expansion und -Differenzierung von multipotenten Stammzellen
KR20040075957A (ko) * 2002-01-23 2004-08-30 유니버시티 오브 유타 리서치 파운데이션 별아교세포 제한 전구체 세포의 순수한 집단과 그것을분리하고 이용하는 방법
ATE365793T1 (de) * 2002-02-19 2007-07-15 Medipost Co Ltd Verfahren zur isolierung und kulturexpansion mesenchymaler stamm-/vorläuferzellen aus nabelschnurblut sowie verfahren zur differenzierung von aus nabelschnurblut stammenden mesenchymalen stamm-/vorläuferzellen in unterschiedliche mesenchymgewebe
EP1571910A4 (en) 2002-11-26 2009-10-28 Anthrogenesis Corp CYTOTHERAPEUTIC AGENTS, CYTOTHERAPEUTIC UNITS AND METHODS OF TREATMENT IN WHICH THEY INTERVENE
US20060228798A1 (en) 2002-11-27 2006-10-12 Catherine Verfaillie Homologous recombination in multipotent adult progenitor cells
EP1583422B1 (en) * 2002-12-05 2016-03-30 Case Western Reserve University Cell-based therapies for ischemia
US7470538B2 (en) * 2002-12-05 2008-12-30 Case Western Reserve University Cell-based therapies for ischemia
JP3762975B2 (ja) * 2003-03-18 2006-04-05 学校法人慶應義塾 単球由来多能性細胞ｍｏｍｃ
US20040203142A1 (en) * 2003-04-14 2004-10-14 Reliance Life Sciences Pvt. Ltd. Growth of neural precursor cells using umbilical cord blood serum and a process for the preparation thereof for therapeutic purposes
US9579351B2 (en) 2003-06-27 2017-02-28 DePuy Synthes Products, Inc. Postpartum cells derived from placental tissue, and methods of making and using the same
US8790637B2 (en) 2003-06-27 2014-07-29 DePuy Synthes Products, LLC Repair and regeneration of ocular tissue using postpartum-derived cells
WO2005001081A1 (en) 2003-06-27 2005-01-06 UNIVERSITé LAVAL Method of isolating cells from umbilical cord
ATE494777T1 (de) * 2003-10-09 2011-01-15 Core Dynamics Ltd Verfahren zum tiefgefrieren, auftauen und transplantieren von lebensfähigem knorpel
CA2549404A1 (en) 2003-12-04 2005-06-23 Regents Of The University Of Minnesota Compositions and methods for the treatment of lysosomal storage disorders
EP1544290A1 (en) * 2003-12-19 2005-06-22 Yu-Show Fu A cell system for generating somatic cells
AU2004308927A1 (en) * 2003-12-19 2005-07-14 Viacell, Inc. Use of human cord blood-derived pluripotent cells for the treatment of disease
GB0329449D0 (en) * 2003-12-19 2004-01-28 Omnicyte Ltd Stem cells
US7935478B2 (en) * 2004-02-02 2011-05-03 Core Dynamics Limited Biological material and methods and solutions for preservation thereof
US8196416B2 (en) * 2004-02-02 2012-06-12 Core Dynamics Limited Device for directional cooling of biological matter
US7863043B2 (en) 2004-02-11 2011-01-04 Aldagen, Inc. Stem cell populations and methods of use
US7622108B2 (en) 2004-04-23 2009-11-24 Bioe, Inc. Multi-lineage progenitor cells
WO2005108559A2 (en) * 2004-04-23 2005-11-17 Bioe, Inc. Multi-lineage progenitor cells
US20070298015A1 (en) * 2004-04-28 2007-12-27 Viacell, Inc. Treatment of Muscular Dystrophy with Mobilized Peripheral Blood Pluripotent Cells
US7790458B2 (en) 2004-05-14 2010-09-07 Becton, Dickinson And Company Material and methods for the growth of hematopoietic stem cells
DE602005019998D1 (de) * 2004-06-07 2010-04-29 Core Dynamics Ltd Verfahren zur sterilisation von biologischen präparaten
EP1778007A1 (en) * 2004-08-12 2007-05-02 I.M.T. Interface Multigrad Technology Ltd. Method and apparatus for freezing or thawing of a biological material
WO2006074308A2 (en) * 2005-01-07 2006-07-13 Wake Forest University Health Sciences Regeneration of pancreatic islets by amniotic fluid stem cell therapy
CA2597757C (en) * 2005-02-10 2016-06-28 Regents Of The University Of Minnesota Vascular/lymphatic endothelial cells
EP1850661A2 (en) * 2005-02-22 2007-11-07 Interface Multigrad Technology (IMT) Ltd. Preserved viable cartilage, method for its preservation, and system and devices used therefor
CN101575590B (zh) * 2005-02-28 2012-05-23 中国医学科学院血液学研究所泰达生命科学技术研究中心 人脐带间充质干细胞的制备方法
EP1874922A4 (en) * 2005-04-19 2009-10-28 Univ Johns Hopkins METHOD USING STROMA CELLS FROM UMBILICAL CORD BLOOD TO DEVELOP AND GRAFT NUCLEAR CELLS DERIVED FROM UMBILICAL CORD BLOOD
CN101218341A (zh) * 2005-05-05 2008-07-09 明尼苏达大学董事会 Nk细胞抑制作用用于促进定植的mhc-i阴性细胞持续存在的用途
WO2006121454A2 (en) * 2005-05-05 2006-11-16 Regents Of The University Of Minnesota Use of mapc or progeny therefrom to populate lymphohematopoietic tissues
EP2662439A1 (en) * 2005-05-27 2013-11-13 Viacord, LLC Treatment of ischemia using stem cells
US20080194024A1 (en) * 2005-07-29 2008-08-14 Mays Robert W Culture of Non-Embryonic Cells at High Cell Density
US8198085B2 (en) * 2005-08-03 2012-06-12 Core Dynamics Limited Somatic cells for use in cell therapy
ATE449165T1 (de) * 2005-08-26 2009-12-15 Seoul Nat Univ Ind Foundation Multipotente blutstammzellen aus der nabelschnur und zellbehandlungsmittel damit zur behandlung der ischämischen krankheit
NZ567082A (en) 2005-10-14 2012-08-31 Univ Minnesota Differentiation of non-embryonic stem cells to cells having a pancreatic phenotype
JP5289970B2 (ja) 2005-12-16 2013-09-11 エシコン・インコーポレイテッド 組織適合性不適合な移植における逆免疫反応を抑制するための組成物および方法
US9125906B2 (en) 2005-12-28 2015-09-08 DePuy Synthes Products, Inc. Treatment of peripheral vascular disease using umbilical cord tissue-derived cells
PT2471906T (pt) 2005-12-29 2019-02-06 Celularity Inc Populações de células estaminais da placenta
CA2646491A1 (en) 2006-04-17 2007-10-25 Bioe, Inc. Differentiation of multi-lineage progenitor cells to respiratory epithelial cells
US7875453B2 (en) * 2006-06-14 2011-01-25 Bioe Llc Differentiation of multi-lineage progenitor cells to hepatocytes
PL2089511T3 (pl) 2006-11-13 2015-02-27 Depuy Synthes Products Llc Rozrost in vitro komórek pochodzących z tkanki pępowinowej wykorzystujących mikronośniki
WO2008085229A2 (en) * 2006-11-15 2008-07-17 Arteriocyte Inc. Cell-based therapies for treating liver disease
US9005964B2 (en) * 2006-11-24 2015-04-14 Regents Of The University Of Minnesota Endodermal progenitor cells
AU2007326171B2 (en) 2006-11-30 2012-11-15 Medipost Co., Ltd. Use of a composition contaning human umbilical cord blood-derived mesenchymal stem cell for inducing differentiation and proliferation of neural precursor cells or neural stem cells to neural cells
WO2009015343A2 (en) * 2007-07-25 2009-01-29 Bioe, Inc. Differentiation of multi-lineage progenitor cells to chondrocytes
WO2009058365A1 (en) * 2007-10-31 2009-05-07 Cryo-Cell International, Inc. Methods for co-culturing cord blood derived cells with menstrual stem cells
US20120156134A1 (en) 2007-12-20 2012-06-21 Shayne Squires Compositions and methods for detecting or eliminating senescent cells to diagnose or treat disease
US20110111492A1 (en) * 2008-01-18 2011-05-12 Regents Of The University Of Minnesota Stem Cell Aggregates and Methods for Making and Using
US20090202978A1 (en) * 2008-02-13 2009-08-13 Ginadi Shaham Method and apparatus for freezing of a biological material
US20090233993A1 (en) * 2008-03-06 2009-09-17 Burnham Institute For Medical Research Compositions and methods for inhibiting gsk3 activity and uses thereof
CN101543644B (zh) * 2008-03-27 2012-07-25 中国人民解放军总医院 无支架工程软骨组织的构建方法及其产品
EP2294187A2 (en) * 2008-05-21 2011-03-16 BioE LLC Differentiation of multi-lineage progenitor cells to pancreatic cells
ES2426241T3 (es) 2008-08-22 2013-10-22 Anthrogenesis Corporation Métodos y composiciones para el tratamiento de defectos óseos con poblaciones de células placentarias
HRP20211788T1 (hr) 2008-08-26 2022-02-18 City Of Hope Postupak i pripravci za poboljšanje anti-tumorskog efektorskog funkcioniranja t stanica
GB0818725D0 (en) 2008-10-13 2008-11-19 Habib Nagy A Pharmaceutical composition
EP2182055A1 (en) 2008-10-14 2010-05-05 Heinrich-Heine-Universität Düsseldorf Human cord blood derived unrestricted somatic stem cells (USSC)
US9057051B2 (en) 2008-10-31 2015-06-16 Katholieke Universiteit Leuven Optimized methods for differentiation of cells into cells with hepatocyte progenitor phenotypes, cells produced by the methods, and methods of using the cells
KR20100054711A (ko) 2008-11-14 2010-05-25 메디포스트(주) 간엽 줄기세포 또는 이의 배양액을 포함하는 신경질환의 예방 또는 치료용 조성물
US10179900B2 (en) 2008-12-19 2019-01-15 DePuy Synthes Products, Inc. Conditioned media and methods of making a conditioned media
EP2456853B1 (en) 2009-07-21 2020-10-28 ABT Holding Company Use of stem cells to reduce leukocyte extravasation
SG10201404281YA (en) * 2009-07-21 2014-09-26 Abt Holding Co Use of stem cells to reduce leukocyte extravasation
US9081008B2 (en) 2009-12-04 2015-07-14 James Sherley Detecting and counting tissue—specific stem cells and uses thereof
US8759098B2 (en) 2009-12-04 2014-06-24 Boston Biomedical Research Institute, Inc. Method for cloning pluripotent stem cells
US20110206647A1 (en) * 2010-02-25 2011-08-25 Abt Holding Company Modulation of Angiogenesis
WO2011106476A1 (en) * 2010-02-25 2011-09-01 Abt Holding Company Modulation of microglia activation
EP2539436B1 (en) 2010-02-25 2021-09-22 ABT Holding Company Modulation of macrophage activation
TW201138792A (en) 2010-04-08 2011-11-16 Anthrogenesis Corp Treatment of sarcoidosis using placental stem cells
EP2568991B3 (en) 2010-05-12 2018-11-28 ABT Holding Company Modulation of splenocytes in cell therapy
US9090878B2 (en) 2010-06-17 2015-07-28 Katholieke Universiteit Leuven Methods for differentiating cells into hepatic stellate cells and hepatic sinusoidal endothelial cells, cells produced by the methods, and methods for using the cells
EP2609425A1 (en) 2010-08-23 2013-07-03 President and Fellows of Harvard College Optogenetic probes for measuring membrane potential
SG10201914007YA (en) 2010-08-24 2020-03-30 Univ Minnesota Non-static suspension culture of cell aggregates
EP2625264B1 (en) 2010-10-08 2022-12-07 Terumo BCT, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
WO2012092485A1 (en) 2010-12-31 2012-07-05 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory rna molecules
EP2697360A1 (en) * 2011-04-11 2014-02-19 Jaffar Ali Bin M. Abdullah Protein-free culture media products
CN102776150A (zh) * 2011-05-13 2012-11-14 上海交通大学医学院附属第九人民医院 一种诱导脐带间充质干细胞分化为内皮细胞的方法
WO2012166844A2 (en) 2011-06-01 2012-12-06 Anthrogenesis Corporation Treatment of pain using placental stem cells
ES2763331T3 (es) 2011-06-06 2020-05-28 ReGenesys BVBA Expansión de células madre en biorreactores de fibra hueca
GB201119335D0 (en) 2011-11-09 2011-12-21 Univ Leuven Kath Hepatitis virus infectable stem cells
US9861660B2 (en) 2013-04-12 2018-01-09 Saverio LaFrancesca Organs for transplantation
AU2014266935B2 (en) 2013-04-30 2020-06-11 Katholieke Universiteit Leuven Cell therapy for myelodysplastic syndromes
EP3068867B1 (en) 2013-11-16 2018-04-18 Terumo BCT, Inc. Expanding cells in a bioreactor
EP2952578A1 (de) 2014-06-03 2015-12-09 Peter Wernet Epigenetische Reprogrammierung von fötalen Stammzellen
IL308324A (en) 2014-09-19 2024-01-01 Hope City IL13RA2-targeted chimeric antigen receptor T cells
TW201613622A (en) * 2014-10-14 2016-04-16 Bionet Corp Composition for skincare and pharmaceutical composition and preparation method thereof
AU2016387339B2 (en) 2016-01-21 2022-11-17 Abt Holding Company Stem cells for wound healing
CN106377547B (zh) * 2016-09-30 2019-05-31 孔五一 脐带血再生粒子的提取方法及其用途
CN113637633B (zh) * 2021-08-16 2023-11-03 浙江大学 一种促进间充质干细胞向成骨细胞分化的方法
CA3232099A1 (en) 2021-09-23 2023-03-30 Adam Ezra Cohen Genetically encoded voltage indicators and uses thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3639949A1 (de) * 1986-11-22 1988-06-09 Diagen Inst Molekularbio Verfahren zur trennung von langkettigen nukleinsaeuren
US5192553A (en) * 1987-11-12 1993-03-09 Biocyte Corporation Isolation and preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood and methods of therapeutic use
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5851832A (en) * 1991-07-08 1998-12-22 Neurospheres, Ltd. In vitro growth and proliferation of multipotent neural stem cells and their progeny
US5672346A (en) * 1992-07-27 1997-09-30 Indiana University Foundation Human stem cell compositions and methods
US6482231B1 (en) * 1995-11-20 2002-11-19 Giovanni Abatangelo Biological material for the repair of connective tissue defects comprising mesenchymal stem cells and hyaluronic acid derivative
US5842477A (en) * 1996-02-21 1998-12-01 Advanced Tissue Sciences, Inc. Method for repairing cartilage
AU2730497A (en) * 1996-04-17 1997-11-07 Case Western Reserve University Cryopreservation and extensive subculturing of human mesenchymal stem cells
US5843633A (en) * 1996-04-26 1998-12-01 Amcell Corporation Characterization of a human hematopoietic progenitor cell antigen
JPH10295369A (ja) 1997-02-26 1998-11-10 Japan Tobacco Inc 造血幹細胞の製造方法
JPH10306027A (ja) 1997-03-07 1998-11-17 Otsuka Pharmaceut Co Ltd 免疫寛容誘導剤
EP1007631B2 (en) * 1997-07-14 2009-02-18 Osiris Therapeutics, Inc. Cardiac muscle regeneration using mesenchymal stem cells
DE19833476B4 (de) 1998-07-24 2005-08-25 Huss, Ralf, Dr. Genetisch modifizierte CD34-Negative, adhärent wachsende hämatopoetische Stammzellen und deren Verwendung in der Gentherapie
EP1180036B1 (en) 1999-04-27 2009-10-07 Layton Bioscience, Inc. Cell therapy for chronic stroke
US20020142457A1 (en) * 1999-12-28 2002-10-03 Akihiro Umezawa Cell having the potentiality of differentiation into cardiomyocytes
ATE365793T1 (de) * 2002-02-19 2007-07-15 Medipost Co Ltd Verfahren zur isolierung und kulturexpansion mesenchymaler stamm-/vorläuferzellen aus nabelschnurblut sowie verfahren zur differenzierung von aus nabelschnurblut stammenden mesenchymalen stamm-/vorläuferzellen in unterschiedliche mesenchymgewebe
US20040197310A1 (en) * 2003-02-12 2004-10-07 Sanberg Paul R. Compositions and methods for using umbilical cord progenitor cells in the treatment of myocardial infarction

Also Published As

Publication number Publication date
EA200300536A1 (ru) 2003-12-25
CN1553951A (zh) 2004-12-08
HUP0301600A2 (hu) 2003-10-28
DE60123293T2 (de) 2007-05-10
UA81390C2 (en) 2008-01-10
US20090238803A1 (en) 2009-09-24
NO20031999L (no) 2003-07-02
ATE340255T1 (de) 2006-10-15
AU2002229533B2 (en) 2007-07-26
IL155608A0 (en) 2003-11-23
EE200300205A (xx) 2003-08-15
DK1404815T3 (da) 2007-01-08
CY1106287T1 (el) 2011-10-12
CA2426987A1 (en) 2002-05-10
SK5242003A3 (en) 2003-11-04
HK1071771A1 (en) 2005-07-29
US20050142118A1 (en) 2005-06-30
CA2426987C (en) 2013-06-11
US7560280B2 (en) 2009-07-14
AU2953302A (en) 2002-05-15
US7556801B2 (en) 2009-07-07
HUP0301600A3 (en) 2005-12-28
CN100480375C (zh) 2009-04-22
IL155608A (en) 2009-08-03
JP2008179642A (ja) 2008-08-07
JP4799804B2 (ja) 2011-10-26
DE60123293D1 (de) 2006-11-02
WO2002036751A3 (en) 2004-01-08
EA008619B1 (ru) 2007-06-29
PT1404815E (pt) 2006-12-29
ES2272563T3 (es) 2007-05-01
MXPA03003844A (es) 2004-10-15
US20020164794A1 (en) 2002-11-07
EP1404815A2 (en) 2004-04-07
WO2002036751A2 (en) 2002-05-10
EP1404815B1 (en) 2006-09-20
NO20031999D0 (no) 2003-05-02
PL362293A1 (en) 2004-10-18
JP4805960B2 (ja) 2011-11-02
JP2004521617A (ja) 2004-07-22
CZ20031165A3 (cs) 2003-10-15

Similar Documents

Publication Publication Date Title
CA2426987C (en) Human cord blood derived unrestricted somatic stem cells (ussc)
Silini et al. Perinatal derivatives: where do we stand? A roadmap of the human placenta and consensus for tissue and cell nomenclature
AU2002229533A1 (en) Human cord blood derived unrestricted somatic stem cells (ussc)
Kulus et al. Mesenchymal stem/stromal cells derived from human and animal perinatal tissues—origins, characteristics, signaling pathways, and clinical trials
Dominici et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement
Sabapathy et al. Human Wharton’s jelly mesenchymal stem cells plasticity augments scar-free skin wound healing with hair growth
Lodie et al. Systematic analysis of reportedly distinct populations of multipotent bone marrow-derived stem cells reveals a lack of distinction
ES2328460T3 (es) Poblaciones de celulas progenitoras, expansion de las mismas y crecimiento de tipos de celulas no hematopoyeticas y tejidos provenientes de las mismas.
Pascucci et al. Flow cytometric characterization of culture expanded multipotent mesenchymal stromal cells (MSCs) from horse adipose tissue: towards the definition of minimal stemness criteria
Wei et al. Primordial germ cell–like cells derived from canine adipose mesenchymal stem cells
KR20140143363A (ko) 기질 줄기 세포
KR20170036105A (ko) 치료학적 용도의 줄기 세포 조성물 및 줄기 세포의 제조 방법
Frontini López et al. Adipose-derived mesenchymal stem/stromal cells: from the lab bench to the basic concepts for clinical translation
Cetrulo et al. Perinatal stem cells
Yousaf et al. Multipotent potential of human adult mesenchymal stem cells
Calavul et al. The role of stem cell in plastic reconstructive and aesthetic surgery
Pavlovic Very small embryonic like cells (VSELs): pros and cons—review and perspectives in the light of critical data and controversies
JP2018501189A (ja) 骨欠損を治療するための体性幹細胞
WO2023227972A1 (en) Process for preparation and cryopreservation of dental pulp from definitive teeth and products thereof based on isolated mesenchymal stem cells
Zheng et al. Bone Marrow Stem Cells: Source, Characterization, Isolation, Culture, and Identification
Lindroos Characterization and optimization of in vitro culture conditions of adult stem cells for clinical cell therapy
JP2022103137A (ja) 多能性幹細胞を含む細胞画分の製造方法
Giovanni Amniotic fluid-derived stems isolation, characterization and differentiation
Messaggio MESENCHYMAL STEM CELLS FROM HUMAN ADIPOSE TISSUE: CHARACTERIZATION AND IMMUNOMODULATORY PROPERTIES OF TISSUE AND CELLULAR PRODUCT
Malagola Isolation and characterization of mesenchymal stromal cells from the canine liver