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BG107047A - Method for the preparation of citalopram - Google Patents

Method for the preparation of citalopram

Info

Publication number
BG107047A
BG107047A BG107047A BG10704702A BG107047A BG 107047 A BG107047 A BG 107047A BG 107047 A BG107047 A BG 107047A BG 10704702 A BG10704702 A BG 10704702A BG 107047 A BG107047 A BG 107047A
Authority
BG
Bulgaria
Prior art keywords
citalopram
preparation
alkylation
fluorophenyl
present
Prior art date
Application number
BG107047A
Other languages
Bulgarian (bg)
English (en)
Inventor
Hans Petersen
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of BG107047A publication Critical patent/BG107047A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Furan Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
BG107047A 2000-03-13 2002-09-02 Method for the preparation of citalopram BG107047A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200000401 2000-03-13
DKPA200000415 2000-03-14
PCT/DK2001/000168 WO2001068631A1 (en) 2000-03-13 2001-03-13 Method for the preparation of citalopram

Publications (1)

Publication Number Publication Date
BG107047A true BG107047A (en) 2003-04-30

Family

ID=26068790

Family Applications (1)

Application Number Title Priority Date Filing Date
BG107047A BG107047A (en) 2000-03-13 2002-09-02 Method for the preparation of citalopram

Country Status (22)

Country Link
US (2) US6762308B2 (hu)
EP (1) EP1265883A1 (hu)
JP (1) JP2003527387A (hu)
KR (1) KR20020080481A (hu)
CN (1) CN1429219A (hu)
AU (1) AU2001242298A1 (hu)
BG (1) BG107047A (hu)
BR (1) BR0109176A (hu)
CA (1) CA2402388A1 (hu)
CZ (1) CZ20023384A3 (hu)
EA (1) EA200200969A1 (hu)
HR (1) HRP20020744A2 (hu)
HU (1) HUP0300274A2 (hu)
IL (1) IL151490A0 (hu)
IS (1) IS6529A (hu)
MX (1) MXPA02008869A (hu)
NO (1) NO20024213L (hu)
NZ (1) NZ521201A (hu)
PL (1) PL360110A1 (hu)
SK (1) SK14602002A3 (hu)
TR (1) TR200202166T2 (hu)
WO (1) WO2001068631A1 (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA004033B1 (ru) * 1999-04-14 2003-12-25 Х.Лундбекк А/С Способ получения циталопрама
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
CA2402388A1 (en) 2000-03-13 2001-09-20 Hans Petersen Method for the preparation of citalopram
NZ521204A (en) 2000-03-13 2004-03-26 H Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)- 1,3-dihydroisobenzofurans for preparing citalopram, an anti depressant
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
EA005094B1 (ru) 2000-03-14 2004-10-28 Х.Лундбекк А/С Способ получения циталопрама
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
AR040970A1 (es) 2002-08-12 2005-04-27 Lundbeck & Co As H Metodo para la separacion de intermediarios que pueden ser utilizados para la preparacion de escitalopram
US20050154052A1 (en) * 2003-03-24 2005-07-14 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
TWI339651B (en) 2004-02-12 2011-04-01 Lundbeck & Co As H Method for the separation of intermediates which may be used for the preparation of escitalopram
US7613106B2 (en) * 2005-01-04 2009-11-03 Avaya Inc. Dial plan transparency for fragmented networks
GB0601286D0 (en) 2006-01-23 2006-03-01 Sandoz Ag Asymmetric synthesis

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143702A (hu) 1965-03-18
GB1526331A (en) 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
CN1206207C (zh) 1997-07-08 2005-06-15 H.隆德贝克有限公司 氰酞氟苯胺的制备方法
UA62985C2 (en) * 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
BR9714925A (pt) 1997-11-11 2003-07-22 Lundbeck & Co As H Método para preparação de citalopran, composto e composição farmacêutica antidepressiva
JP3892667B2 (ja) 1998-10-20 2007-03-14 ハー・ルンドベック・アクチエゼルスカベット シタロプラムの製造方法
UA70979C2 (uk) 1998-12-23 2004-11-15 Х. Луннбек А/С Спосіб одержання 5-ціанофталіду
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
EA004033B1 (ru) 1999-04-14 2003-12-25 Х.Лундбекк А/С Способ получения циталопрама
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
GB2360281B (en) 1999-10-25 2002-01-16 Lundbeck & Co As H Method for the preparation of citalopram
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
PT1246812E (pt) 1999-12-28 2004-08-31 Lundbeck & Co As H Metodo para a preparacao de citalopram
CZ20022627A3 (cs) 1999-12-30 2002-10-16 H. Lundbeck A/S Způsob výroby citalopramu
JP2003519691A (ja) 2000-01-14 2003-06-24 ハー・ルンドベック・アクチエゼルスカベット ５−シアノフタリドの製造方法
US6433196B1 (en) 2000-02-17 2002-08-13 Sumika Fine Chemicals Co., Ltd. Production method of citalopram, intermediate therefor and production method of the intermediate
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
CA2402388A1 (en) 2000-03-13 2001-09-20 Hans Petersen Method for the preparation of citalopram
EA005094B1 (ru) 2000-03-14 2004-10-28 Х.Лундбекк А/С Способ получения циталопрама
ES2159271B1 (es) 2000-03-16 2002-05-01 Lundbeck & Co As H Metodo para la preparacion de 5-ciano-1-(4-fluorofenil)-1,3-dihidroisobenzofuranos
CZ2002832A3 (cs) 2000-07-06 2002-05-15 H. Lundbeck A/S Způsob výroby citalopramu
FI20011622L (fi) 2000-08-18 2002-02-19 Lundbeck & Co As H Menetelmä sitalopraamin valmistamiseksi
PL205724B1 (pl) 2000-12-22 2010-05-31 Lundbeck & Co As H Sposób wytwarzania citalopramu
JP2003519121A (ja) 2000-12-28 2003-06-17 ハー・ルンドベック・アクチエゼルスカベット 純粋なシタロプラムの製造方法

Also Published As

Publication number Publication date
CA2402388A1 (en) 2001-09-20
SK14602002A3 (sk) 2003-02-04
MXPA02008869A (es) 2003-02-10
JP2003527387A (ja) 2003-09-16
NZ521201A (en) 2004-02-27
PL360110A1 (en) 2004-09-06
KR20020080481A (ko) 2002-10-23
US6762308B2 (en) 2004-07-13
IL151490A0 (en) 2003-04-10
IS6529A (is) 2002-08-27
EA200200969A1 (ru) 2003-02-27
HRP20020744A2 (en) 2004-12-31
NO20024213L (no) 2002-11-13
US20040215025A1 (en) 2004-10-28
US20030092919A1 (en) 2003-05-15
HUP0300274A2 (hu) 2003-06-28
WO2001068631A1 (en) 2001-09-20
CZ20023384A3 (cs) 2003-01-15
BR0109176A (pt) 2003-04-22
AU2001242298A1 (en) 2001-09-24
TR200202166T2 (tr) 2002-12-23
NO20024213D0 (no) 2002-09-04
US6992198B2 (en) 2006-01-31
CN1429219A (zh) 2003-07-09
EP1265883A1 (en) 2002-12-18

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