BG104903A - Метод за получаване на свързани със смола циклични пептиди - Google Patents

Метод за получаване на свързани със смола циклични пептиди Download PDF

Info

Publication number: BG104903A
Authority: BG; Bulgaria
Prior art keywords: peptide; asp; lys; amino acid; formula
Prior art date: 1998-04-15

Application number

BG104903A

Other languages

Bulgarian (bg)

English (en)

Inventor

Adam SLEDESKI

James Mencel

Original Assignee

Aventis Pharmaceuticals Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-04-15

Filing date

2000-11-02

Publication date

2001-07-31

2000-11-02 Application filed by Aventis Pharmaceuticals Inc. filed Critical Aventis Pharmaceuticals Inc.

2001-07-31 Publication of BG104903A publication Critical patent/BG104903A/bg

Links

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IZTQOLKUZKXIRV-YRVFCXMDSA-N sincalide Chemical class C([C@@H](C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](N)CC(O)=O)C1=CC=C(OS(O)(=O)=O)C=C1 IZTQOLKUZKXIRV-YRVFCXMDSA-N 0.000 description 1
BAZAXWOYCMUHIX-UHFFFAOYSA-M sodium perchlorate Chemical compound [Na+].[O-]Cl(=O)(=O)=O BAZAXWOYCMUHIX-UHFFFAOYSA-M 0.000 description 1
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NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical class C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 description 1
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USFPINLPPFWTJW-UHFFFAOYSA-N tetraphenylphosphonium Chemical compound C1=CC=CC=C1[P+](C=1C=CC=CC=1)(C=1C=CC=CC=1)C1=CC=CC=C1 USFPINLPPFWTJW-UHFFFAOYSA-N 0.000 description 1
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/02—Peptides being immobilised on, or in, an organic carrier
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06182—Dipeptides with the first amino acid being heterocyclic and Pristinamycin II; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Endocrinology (AREA)
Analytical Chemistry (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

BG104903A 1998-04-15 2000-11-02 Метод за получаване на свързани със смола циклични пептиди BG104903A (bg)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US8189798P	1998-04-15	1998-04-15
PCT/US1999/008435 WO1999052933A1 (en)	1998-04-15	1999-04-15	Process for the preparation of resin-bound cyclic peptides

Publications (1)

Publication Number	Publication Date
BG104903A true BG104903A (bg)	2001-07-31

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ID=22167111

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Application Number	Title	Priority Date	Filing Date
BG104903A BG104903A (bg)	1998-04-15	2000-11-02	Метод за получаване на свързани със смола циклични пептиди

Country Status (20)

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US (1)	US6569993B1 (zh)
EP (1)	EP1093458A4 (zh)
JP (1)	JP2002511483A (zh)
KR (1)	KR20010085236A (zh)
CN (2)	CN1163504C (zh)
AP (1)	AP1117A (zh)
AU (1)	AU744812B2 (zh)
BG (1)	BG104903A (zh)
BR (1)	BR9909634A (zh)
CA (1)	CA2325572A1 (zh)
CZ (1)	CZ20003798A3 (zh)
EA (1)	EA200001071A1 (zh)
HU (1)	HUP0101629A2 (zh)
IL (1)	IL138338A0 (zh)
NO (1)	NO20005165L (zh)
OA (1)	OA11501A (zh)
PL (1)	PL347103A1 (zh)
SK (1)	SK15352000A3 (zh)
UA (1)	UA72460C2 (zh)
WO (1)	WO1999052933A1 (zh)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA72460C2 (en)	1998-04-15	2005-03-15	Aventic Pharmaceuticals Inc	A process for the preparation of polymer- bound cyclic peptides
GB9912911D0 (en) *	1999-06-04	1999-08-04	Zeneca Ltd	Chemical process
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1999
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- 1999-04-15 AP APAP/P/2000/001972A patent/AP1117A/en active
- 1999-04-15 JP JP2000543489A patent/JP2002511483A/ja active Pending
- 1999-04-15 EP EP99917595A patent/EP1093458A4/en not_active Withdrawn
- 1999-04-15 AU AU35679/99A patent/AU744812B2/en not_active Ceased
- 1999-04-15 CA CA002325572A patent/CA2325572A1/en not_active Abandoned
- 1999-04-15 EA EA200001071A patent/EA200001071A1/ru unknown
- 1999-04-15 WO PCT/US1999/008435 patent/WO1999052933A1/en not_active Application Discontinuation
- 1999-04-15 KR KR1020007011446A patent/KR20010085236A/ko not_active Application Discontinuation
- 1999-04-15 HU HU0101629A patent/HUP0101629A2/hu unknown
- 1999-04-15 CZ CZ20003798A patent/CZ20003798A3/cs unknown
- 1999-04-15 CN CNB998119709A patent/CN1163504C/zh not_active Expired - Fee Related
- 1999-04-15 IL IL13833899A patent/IL138338A0/xx unknown
- 1999-04-15 BR BR9909634-0A patent/BR9909634A/pt not_active IP Right Cessation
- 1999-04-15 CN CNA2004100386677A patent/CN1552737A/zh active Pending
- 1999-04-15 SK SK1535-2000A patent/SK15352000A3/sk unknown
- 1999-04-15 PL PL99347103A patent/PL347103A1/xx not_active Application Discontinuation
- 1999-11-18 US US09/442,989 patent/US6569993B1/en not_active Expired - Fee Related
2000
- 2000-10-13 OA OA1200000283A patent/OA11501A/en unknown
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JP2002511483A (ja)	2002-04-16
AP1117A (en)	2002-11-02
CN1323313A (zh)	2001-11-21
CN1552737A (zh)	2004-12-08
PL347103A1 (en)	2002-03-25
NO20005165D0 (no)	2000-10-13
CA2325572A1 (en)	1999-10-21
CZ20003798A3 (cs)	2001-08-15
CN1163504C (zh)	2004-08-25
EA200001071A1 (ru)	2001-08-27
US6569993B1 (en)	2003-05-27
EP1093458A4 (en)	2001-07-18
KR20010085236A (ko)	2001-09-07
UA72460C2 (en)	2005-03-15
NO20005165L (no)	2000-12-15
AP2000001972A0 (en)	2000-12-31
OA11501A (en)	2004-05-14
AU3567999A (en)	1999-11-01
SK15352000A3 (sk)	2001-04-09
EP1093458A1 (en)	2001-04-25
IL138338A0 (en)	2001-10-31
WO1999052933A1 (en)	1999-10-21
AU744812B2 (en)	2002-03-07
HUP0101629A2 (en)	2003-03-28
BR9909634A (pt)	2001-10-16

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