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AU2001269836A1 - Proteases - Google Patents

Proteases

Info

Publication number
AU2001269836A1
AU2001269836A1 AU2001269836A AU6983601A AU2001269836A1 AU 2001269836 A1 AU2001269836 A1 AU 2001269836A1 AU 2001269836 A AU2001269836 A AU 2001269836A AU 6983601 A AU6983601 A AU 6983601A AU 2001269836 A1 AU2001269836 A1 AU 2001269836A1
Authority
AU
Australia
Prior art keywords
proteases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001269836A
Inventor
Chandra S. Arvizu
Janice Au-Young
Yalda Azimzai
Mariah R. Baughn
Narinder K. Chawla
Debopriya Das
Angelo M Delegeane
Vicki S. Elliott
Ameena R. Gandhi
April Hafalia
Deborah A. Kallick
Liam Kearney
Farrah A. Khan
Preeti Lal
Ernestine A. Lee
Dyung Aina M. Lu
Yan Lu
Danniel B. Nguyen
Jayalaxmi Ramkumar
Roopa Reddy
Y. Tom Tang
Catherine M. Tribouley
Roderick T. Walsh
Yuming Xu
Monique G. Yao
Henry Yue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Publication of AU2001269836A1 publication Critical patent/AU2001269836A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2001269836A 2000-06-16 2001-06-13 Proteases Abandoned AU2001269836A1 (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US21233600P 2000-06-16 2000-06-16
US60/212,336 2000-06-16
US21395500P 2000-06-22 2000-06-22
US60/213,955 2000-06-22
US21539600P 2000-06-29 2000-06-29
US60/215,396 2000-06-29
US21682100P 2000-07-07 2000-07-07
US60/216,821 2000-07-07
US21894600P 2000-07-14 2000-07-14
US60/218,946 2000-07-14
PCT/US2001/019178 WO2001098468A2 (en) 2000-06-16 2001-06-13 Proteases

Publications (1)

Publication Number Publication Date
AU2001269836A1 true AU2001269836A1 (en) 2002-01-02

Family

ID=27539651

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001269836A Abandoned AU2001269836A1 (en) 2000-06-16 2001-06-13 Proteases

Country Status (5)

Country Link
EP (1) EP1292684A2 (en)
JP (1) JP2004515217A (en)
AU (1) AU2001269836A1 (en)
CA (1) CA2411971A1 (en)
WO (1) WO2001098468A2 (en)

Families Citing this family (67)

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CN1163594C (en) 1997-09-29 2004-08-25 尖端医疗有限公司 Stimulation of hematopoietic cells in vitro
US6979697B1 (en) 1998-08-21 2005-12-27 Point Therapeutics, Inc. Regulation of substrate activity
US20030096391A1 (en) * 2000-12-22 2003-05-22 Millennium Pharmaceuticals, Inc. 17903, a novel human aminopeptidase and uses therefor
US6716613B1 (en) * 1999-11-11 2004-04-06 Yamanouchi Pharmaceutical Co., Ltd. Metalloprotease having aggrecanase activity
US7700341B2 (en) 2000-02-03 2010-04-20 Dendreon Corporation Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon
AU2001257594A1 (en) * 2000-04-18 2001-10-30 Millennium Pharmaceuticals, Inc. 21953, a novel human prolyl oligopeptidase family member and uses thereof
US20030083244A1 (en) * 2000-04-26 2003-05-01 Vernet Corine A.M. Novel proteins and nucleic acids encoding same
WO2001083782A2 (en) * 2000-05-04 2001-11-08 Sugen, Inc. Novel proteases
EP1297006B1 (en) 2000-06-23 2006-02-08 Bayer HealthCare AG Regulation of human prostasin-like serine protease
EP1297154A2 (en) * 2000-06-26 2003-04-02 Bayer Aktiengesellschaft Regulation of human caspase-1-like protease
AU2002222937A1 (en) * 2000-07-18 2002-01-30 Millennium Pharmaceuticals, Inc. 14087, a serine protease molecule and uses therefor
JP2004526407A (en) * 2000-08-07 2004-09-02 バイエル アクチェンゲゼルシャフト Regulation of human membrane serine protease
GB0020345D0 (en) * 2000-08-17 2000-10-04 Glaxo Group Ltd Protein
CA2420487A1 (en) * 2000-08-22 2002-02-28 Lexicon Genetics Incorporated Novel human proteases and polynucleotides encoding the same
AU2002215312A1 (en) * 2000-09-29 2002-04-08 Lexicon Genetics Incorporated Human proteases and polynucleotides encoding the same
CZ20031301A3 (en) * 2000-10-12 2003-10-15 Ferring Bv Isolated nucleic acid, polypeptide, expression vector and antibody
US20020119555A1 (en) * 2000-12-22 2002-08-29 Rajasehkar Bandaru 53014, a human metalloprotease family member and uses therefor
GB0101760D0 (en) * 2001-01-23 2001-03-07 Glaxo Group Ltd Novel protein
WO2002072786A2 (en) 2001-03-13 2002-09-19 Corvas International, Inc. Nucleic acid molecules encoding a transmembrane serine protease 7, the encoded polypeptides and methods based thereon
WO2002077263A2 (en) * 2001-03-22 2002-10-03 Dendreon San Diego Llc Nucleic acid molecules encoding serine protease cvsp14, the encoded polypeptides and methods based thereon
US7034134B2 (en) 2001-04-26 2006-04-25 Bristol-Myers Squibb Company Polynucleotide encoding a novel metalloprotease highly expressed in the testis, MMP-29
WO2002092841A2 (en) * 2001-05-14 2002-11-21 Dendreon San Diego Llc Nucleic acid molecules encoding a transmembrane serine protease 10, the encoded polypeptides and methods based thereon
WO2003012038A2 (en) 2001-07-27 2003-02-13 Wyeth Aggrecanase molecules
JP2003180384A (en) * 2001-09-24 2003-07-02 Daiichi Fine Chemical Co Ltd Adamts-15, -16, -17, -18 and -19
WO2003042379A2 (en) * 2001-11-13 2003-05-22 Universite De Liege A new disintegrin and metalloproteinase with thrombospondin type i repeats polynucleotide and its encoded polypeptide
WO2003064651A2 (en) * 2002-01-28 2003-08-07 Bayer Healthcare Ag Regulation of human membrane-type serine protease
CA2532130C (en) * 2003-09-20 2016-07-19 Electrophoretics Limited Diagnostic method for brain damage-related disorders
WO2005040792A2 (en) * 2003-10-21 2005-05-06 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with arginyl aminopeptidase (aminopeptidase b)-like 1 (rnpepl1)
WO2005106021A1 (en) * 2004-04-28 2005-11-10 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with dipeptidyl-peptidase 8 (dpp8)
WO2005118632A1 (en) * 2004-05-27 2005-12-15 Vib Vzw A NOVEL HUMAN CARD-ONLY PROTEIN THAT INHIBITS PRO-IL-1β MATURATION
EP2032701B1 (en) * 2006-06-23 2013-11-27 Alethia Biotherapeutics Inc. Polynucleotides and polypeptides involved in cancer
US7572618B2 (en) 2006-06-30 2009-08-11 Bristol-Myers Squibb Company Polynucleotides encoding novel PCSK9 variants
JP5588175B2 (en) 2006-11-07 2014-09-10 メルク・シャープ・アンド・ドーム・コーポレーション PCSK9 antagonist
CA2680832A1 (en) 2007-03-27 2008-10-02 Merck & Co., Inc. Method for detecting autoprocessed, secreted pcsk9
JOP20080381B1 (en) 2007-08-23 2023-03-28 Amgen Inc Antigen Binding Proteins to Proprotein Convertase subtillisin Kexin type 9 (pcsk9)
AR070315A1 (en) 2008-02-07 2010-03-31 Merck & Co Inc ANTIBODIES 1B20 ANTAGONISTS OF PCSK9
AR070316A1 (en) 2008-02-07 2010-03-31 Merck & Co Inc PCSK9 ANTAGONISTS (SUBTILISINE-KEXINA TYPE 9 PROPROTEIN)
MX336869B (en) 2008-11-03 2016-02-04 Alethia Biotherapeutics Inc Antibodies that specifically block the biological activity of a tumor antigen.
WO2010068526A1 (en) 2008-12-12 2010-06-17 Merck Sharp & Dohme Corp. Pcsk9 immunoassay
IN2012DN03824A (en) 2009-10-30 2015-08-28 Merck Sharp & Dohme
CN102596249A (en) 2009-10-30 2012-07-18 默沙东公司 AX1 and AX189 PCSK9 antagonists and variants
CN106146664B (en) 2011-03-31 2021-09-07 Adc治疗股份有限公司 Antibodies against kidney-associated antigen 1 and antigen-binding fragments thereof
JOP20200043A1 (en) 2011-05-10 2017-06-16 Amgen Inc Ways to treat or prevent cholesterol disorders
PL2802351T3 (en) 2012-01-09 2019-11-29 Adc Therapeutics Sa Agents for treating triple negative breast cancer
WO2013188855A1 (en) 2012-06-15 2013-12-19 Genentech, Inc. Anti-pcsk9 antibodies, formulations, dosing, and methods of use
CA2909442A1 (en) 2013-04-17 2014-10-23 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
US9067998B1 (en) 2014-07-15 2015-06-30 Kymab Limited Targeting PD-1 variants for treatment of cancer
US9017678B1 (en) 2014-07-15 2015-04-28 Kymab Limited Method of treating rheumatoid arthritis using antibody to IL6R
US9914769B2 (en) 2014-07-15 2018-03-13 Kymab Limited Precision medicine for cholesterol treatment
US8992927B1 (en) 2014-07-15 2015-03-31 Kymab Limited Targeting human NAV1.7 variants for treatment of pain
US8980273B1 (en) 2014-07-15 2015-03-17 Kymab Limited Method of treating atopic dermatitis or asthma using antibody to IL4RA
US8986694B1 (en) 2014-07-15 2015-03-24 Kymab Limited Targeting human nav1.7 variants for treatment of pain
US8883157B1 (en) 2013-12-17 2014-11-11 Kymab Limited Targeting rare human PCSK9 variants for cholesterol treatment
US9023359B1 (en) 2014-07-15 2015-05-05 Kymab Limited Targeting rare human PCSK9 variants for cholesterol treatment
US9051378B1 (en) 2014-07-15 2015-06-09 Kymab Limited Targeting rare human PCSK9 variants for cholesterol treatment
US9045548B1 (en) 2014-07-15 2015-06-02 Kymab Limited Precision Medicine by targeting rare human PCSK9 variants for cholesterol treatment
US8945560B1 (en) 2014-07-15 2015-02-03 Kymab Limited Method of treating rheumatoid arthritis using antibody to IL6R
US9034332B1 (en) 2014-07-15 2015-05-19 Kymab Limited Precision medicine by targeting rare human PCSK9 variants for cholesterol treatment
US8986691B1 (en) 2014-07-15 2015-03-24 Kymab Limited Method of treating atopic dermatitis or asthma using antibody to IL4RA
US9045545B1 (en) 2014-07-15 2015-06-02 Kymab Limited Precision medicine by targeting PD-L1 variants for treatment of cancer
GB201403775D0 (en) 2014-03-04 2014-04-16 Kymab Ltd Antibodies, uses & methods
US9150660B1 (en) 2014-07-15 2015-10-06 Kymab Limited Precision Medicine by targeting human NAV1.8 variants for treatment of pain
US9139648B1 (en) 2014-07-15 2015-09-22 Kymab Limited Precision medicine by targeting human NAV1.9 variants for treatment of pain
SG11201810509PA (en) 2016-06-20 2018-12-28 Kymab Ltd Anti-pd-l1 antibodies
US11779604B2 (en) 2016-11-03 2023-10-10 Kymab Limited Antibodies, combinations comprising antibodies, biomarkers, uses and methods
WO2018119354A1 (en) 2016-12-23 2018-06-28 President And Fellows Of Harvard College Gene editing of pcsk9
JP7457833B2 (en) 2020-04-09 2024-03-28 ヴァーヴ・セラピューティクス，インコーポレーテッド Base editing of ANGPTL3 and methods of using it to treat disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5932422A (en) * 1997-11-14 1999-08-03 Millennium Pharmaceuticals, Inc. Modulation of drug resistance via ubiquitin carboxy-terminal hydrolase
JP2002539811A (en) * 1999-03-26 2002-11-26 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド 48 human secreted proteins
JP2004501637A (en) * 2000-06-26 2004-01-22 スージェン・インコーポレーテッド New protease

Also Published As

Publication number Publication date
CA2411971A1 (en) 2001-12-27
JP2004515217A (en) 2004-05-27
EP1292684A2 (en) 2003-03-19
WO2001098468A2 (en) 2001-12-27
WO2001098468A3 (en) 2003-01-03

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